LOCUS       DAVLZG010000001       114832 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLZG010000001 DAVLZG010000000
VERSION     DAVLZG010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 114832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114832
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.001"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            68..430
                     /locus_tag="VYO72_000001"
     CDS             68..430
                     /locus_tag="VYO72_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706458.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQAKRIHRA
                     FCVRLCLKAQFLLSNNDS"
     gene            611..910
                     /locus_tag="VYO72_000002"
     CDS             611..910
                     /locus_tag="VYO72_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706459.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1005..1442)
                     /locus_tag="VYO72_000003"
     CDS             complement(1005..1442)
                     /locus_tag="VYO72_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706460.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1544..2209)
                     /locus_tag="VYO72_000004"
     CDS             complement(1544..2209)
                     /locus_tag="VYO72_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1706461.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(2397..3047)
                     /locus_tag="VYO72_000005"
     CDS             complement(2397..3047)
                     /locus_tag="VYO72_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1706462.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3159..4001
                     /locus_tag="VYO72_000006"
     CDS             3159..4001
                     /locus_tag="VYO72_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1706463.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQENFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4077..4514
                     /locus_tag="VYO72_000007"
     CDS             4077..4514
                     /locus_tag="VYO72_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1706464.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4583..4885
                     /locus_tag="VYO72_000008"
     CDS             4583..4885
                     /locus_tag="VYO72_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706465.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(4976..6049)
                     /locus_tag="VYO72_000009"
     CDS             complement(4976..6049)
                     /locus_tag="VYO72_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1706466.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            6205..6882
                     /locus_tag="VYO72_000010"
     CDS             6205..6882
                     /locus_tag="VYO72_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1706467.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            6875..7849
                     /locus_tag="VYO72_000011"
     CDS             6875..7849
                     /locus_tag="VYO72_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1706468.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLFLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(7898..9841)
                     /gene="thrS"
                     /locus_tag="VYO72_000012"
     CDS             complement(7898..9841)
                     /gene="thrS"
                     /locus_tag="VYO72_000012"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1706469.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNIAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVNYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(9899..10222)
                     /locus_tag="VYO72_000013"
     CDS             complement(9899..10222)
                     /locus_tag="VYO72_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1706470.1"
                     /translation="MELQELVEHSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            11087..11632
                     /locus_tag="VYO72_000014"
     CDS             11087..11632
                     /locus_tag="VYO72_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1706471.1"
                     /translation="MKLAVIAANGQVGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            11858..12127
                     /gene="rpsO"
                     /locus_tag="VYO72_000015"
     CDS             11858..12127
                     /gene="rpsO"
                     /locus_tag="VYO72_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1706472.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            12943..13557
                     /locus_tag="VYO72_000016"
     CDS             12943..13557
                     /locus_tag="VYO72_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1706473.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(13850..14599)
                     /locus_tag="VYO72_000017"
     CDS             complement(13850..14599)
                     /locus_tag="VYO72_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1706474.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMILKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            14732..17068
                     /locus_tag="VYO72_000018"
     CDS             14732..17068
                     /locus_tag="VYO72_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1706475.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            17169..17846
                     /locus_tag="VYO72_000019"
     CDS             17169..17846
                     /locus_tag="VYO72_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1706476.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            17833..18630
                     /locus_tag="VYO72_000020"
     CDS             17833..18630
                     /locus_tag="VYO72_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1706477.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18647..19750
                     /locus_tag="VYO72_000021"
     CDS             18647..19750
                     /locus_tag="VYO72_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1706478.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWLSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLSILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            19757..19948
                     /locus_tag="VYO72_000022"
     CDS             19757..19948
                     /locus_tag="VYO72_000022"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706479.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20051..21070
                     /gene="galE"
                     /locus_tag="VYO72_000023"
     CDS             20051..21070
                     /gene="galE"
                     /locus_tag="VYO72_000023"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1706480.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21072..22037
                     /locus_tag="VYO72_000024"
     CDS             21072..22037
                     /locus_tag="VYO72_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1706481.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(22088..22294)
                     /locus_tag="VYO72_000025"
     CDS             complement(22088..22294)
                     /locus_tag="VYO72_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1706482.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            22346..22822
                     /locus_tag="VYO72_000026"
     CDS             22346..22822
                     /locus_tag="VYO72_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1706483.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            22831..23502
                     /locus_tag="VYO72_000027"
     CDS             22831..23502
                     /locus_tag="VYO72_000027"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1706484.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            23632..23970
                     /locus_tag="VYO72_000028"
     CDS             23632..23970
                     /locus_tag="VYO72_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1706485.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIHIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            23973..24602
                     /locus_tag="VYO72_000029"
     CDS             23973..24602
                     /locus_tag="VYO72_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1706486.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            24842..25993
                     /locus_tag="VYO72_000030"
     CDS             24842..25993
                     /locus_tag="VYO72_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1706487.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGARLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            26311..27060
                     /gene="truA"
                     /locus_tag="VYO72_000031"
     CDS             26311..27060
                     /gene="truA"
                     /locus_tag="VYO72_000031"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1706488.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            27050..27823
                     /locus_tag="VYO72_000032"
     CDS             27050..27823
                     /locus_tag="VYO72_000032"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1706489.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            27801..28262
                     /locus_tag="VYO72_000033"
     CDS             27801..28262
                     /locus_tag="VYO72_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1706490.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(28521..28724)
                     /locus_tag="VYO72_000034"
     CDS             complement(28521..28724)
                     /locus_tag="VYO72_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1706491.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(28717..29799)
                     /locus_tag="VYO72_000035"
     CDS             complement(28717..29799)
                     /locus_tag="VYO72_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1706492.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(29925..30707)
                     /locus_tag="VYO72_000036"
     CDS             complement(29925..30707)
                     /locus_tag="VYO72_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1706493.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(30707..32050)
                     /locus_tag="VYO72_000037"
     CDS             complement(30707..32050)
                     /locus_tag="VYO72_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1706494.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDVQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(32149..33465)
                     /locus_tag="VYO72_000038"
     CDS             complement(32149..33465)
                     /locus_tag="VYO72_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1706495.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDINGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            33658..34884
                     /locus_tag="VYO72_000039"
     CDS             33658..34884
                     /locus_tag="VYO72_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1706496.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            35083..36657
                     /locus_tag="VYO72_000040"
     CDS             35083..36657
                     /locus_tag="VYO72_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1706497.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            36921..37709
                     /gene="codY"
                     /locus_tag="VYO72_000041"
     CDS             36921..37709
                     /gene="codY"
                     /locus_tag="VYO72_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1706498.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            37709..38284
                     /locus_tag="VYO72_000042"
     CDS             37709..38284
                     /locus_tag="VYO72_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1706499.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            38366..38451
                     /locus_tag="VYO72_000043"
     tRNA            38366..38451
                     /locus_tag="VYO72_000043"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38400..38402,aa:Leu,seq:aag)
     gene            38734..39864
                     /gene="ugpC"
                     /locus_tag="VYO72_000044"
     CDS             38734..39864
                     /gene="ugpC"
                     /locus_tag="VYO72_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1706500.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(39986..40156)
                     /locus_tag="VYO72_000045"
     CDS             complement(39986..40156)
                     /locus_tag="VYO72_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706501.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEYKEHHNIDA"
     gene            40363..41121
                     /locus_tag="VYO72_000046"
     CDS             40363..41121
                     /locus_tag="VYO72_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1706502.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            41209..41721
                     /locus_tag="VYO72_000047"
     CDS             41209..41721
                     /locus_tag="VYO72_000047"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1706503.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            41903..42847
                     /locus_tag="VYO72_000048"
     CDS             41903..42847
                     /locus_tag="VYO72_000048"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1706504.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            42856..43533
                     /locus_tag="VYO72_000049"
     CDS             42856..43533
                     /locus_tag="VYO72_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1706505.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            43631..44389
                     /locus_tag="VYO72_000050"
     CDS             43631..44389
                     /locus_tag="VYO72_000050"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1706506.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            44427..45932
                     /gene="lytC"
                     /locus_tag="VYO72_000051"
     CDS             44427..45932
                     /gene="lytC"
                     /locus_tag="VYO72_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1706507.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRNGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            46428..46946
                     /locus_tag="VYO72_000052"
     CDS             46428..46946
                     /locus_tag="VYO72_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1706508.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            47076..47582
                     /locus_tag="VYO72_000053"
     CDS             47076..47582
                     /locus_tag="VYO72_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1706509.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            47582..47752
                     /locus_tag="VYO72_000054"
     CDS             47582..47752
                     /locus_tag="VYO72_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706510.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            47784..49016
                     /gene="clpX"
                     /locus_tag="VYO72_000055"
     CDS             47784..49016
                     /gene="clpX"
                     /locus_tag="VYO72_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1706511.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            49025..49612
                     /locus_tag="VYO72_000056"
     CDS             49025..49612
                     /locus_tag="VYO72_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1706512.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            49623..50003
                     /locus_tag="VYO72_000057"
     CDS             49623..50003
                     /locus_tag="VYO72_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1706513.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            50055..50945
                     /gene="rapZ"
                     /locus_tag="VYO72_000058"
     CDS             50055..50945
                     /gene="rapZ"
                     /locus_tag="VYO72_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1706514.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            50942..51919
                     /locus_tag="VYO72_000059"
     CDS             50942..51919
                     /locus_tag="VYO72_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1706515.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            51916..52827
                     /gene="whiA"
                     /locus_tag="VYO72_000060"
     CDS             51916..52827
                     /gene="whiA"
                     /locus_tag="VYO72_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1706516.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(52861..53829)
                     /locus_tag="VYO72_000061"
     CDS             complement(52861..53829)
                     /locus_tag="VYO72_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1706517.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            53965..54822
                     /locus_tag="VYO72_000062"
     CDS             53965..54822
                     /locus_tag="VYO72_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1706518.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            54809..55588
                     /locus_tag="VYO72_000063"
     CDS             54809..55588
                     /locus_tag="VYO72_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1706519.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            55612..56964
                     /locus_tag="VYO72_000064"
     CDS             55612..56964
                     /locus_tag="VYO72_000064"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1706520.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGNIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            57038..57412
                     /locus_tag="VYO72_000065"
     CDS             57038..57412
                     /locus_tag="VYO72_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1706521.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            57414..58262
                     /locus_tag="VYO72_000066"
     CDS             57414..58262
                     /locus_tag="VYO72_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1706522.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            58539..59306
                     /locus_tag="VYO72_000067"
     CDS             58539..59306
                     /locus_tag="VYO72_000067"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1706523.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMHIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            59318..60502
                     /locus_tag="VYO72_000068"
     CDS             59318..60502
                     /locus_tag="VYO72_000068"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1706524.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            60499..62370
                     /locus_tag="VYO72_000069"
     CDS             60499..62370
                     /locus_tag="VYO72_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1706525.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(62513..63697)
                     /gene="mntE"
                     /locus_tag="VYO72_000070"
     CDS             complement(62513..63697)
                     /gene="mntE"
                     /locus_tag="VYO72_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1706526.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            64001..66697
                     /locus_tag="VYO72_000071"
     CDS             64001..66697
                     /locus_tag="VYO72_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1706527.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVDLATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            66710..67501
                     /gene="yghU"
                     /locus_tag="VYO72_000072"
     CDS             66710..67501
                     /gene="yghU"
                     /locus_tag="VYO72_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1706528.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRQTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QENLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            67617..68027
                     /locus_tag="VYO72_000073"
     CDS             67617..68027
                     /locus_tag="VYO72_000073"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1706529.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            68039..69634
                     /locus_tag="VYO72_000074"
     CDS             68039..69634
                     /locus_tag="VYO72_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706530.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            69801..69965
                     /locus_tag="VYO72_000075"
     CDS             69801..69965
                     /locus_tag="VYO72_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1706531.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            70044..70772
                     /gene="yaaA"
                     /locus_tag="VYO72_000076"
     CDS             70044..70772
                     /gene="yaaA"
                     /locus_tag="VYO72_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1706532.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(71050..71598)
                     /locus_tag="VYO72_000077"
     CDS             complement(71050..71598)
                     /locus_tag="VYO72_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1706533.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            71919..72428
                     /locus_tag="VYO72_000078"
     CDS             71919..72428
                     /locus_tag="VYO72_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1706534.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GLWNYPTVF"
     gene            72404..73591
                     /locus_tag="VYO72_000079"
     CDS             72404..73591
                     /locus_tag="VYO72_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1706535.1"
                     /translation="MELSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            73584..73949
                     /locus_tag="VYO72_000080"
     CDS             73584..73949
                     /locus_tag="VYO72_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1706536.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            73965..75311
                     /gene="asnS"
                     /locus_tag="VYO72_000081"
     CDS             73965..75311
                     /gene="asnS"
                     /locus_tag="VYO72_000081"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1706537.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            75464..75754
                     /locus_tag="VYO72_000082"
     CDS             75464..75754
                     /locus_tag="VYO72_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1706538.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            75766..76236
                     /gene="ssbA"
                     /locus_tag="VYO72_000083"
     CDS             75766..76236
                     /gene="ssbA"
                     /locus_tag="VYO72_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1706539.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            76268..76507
                     /locus_tag="VYO72_000084"
     CDS             76268..76507
                     /locus_tag="VYO72_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1706540.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            76802..78202
                     /locus_tag="VYO72_000085"
     CDS             76802..78202
                     /locus_tag="VYO72_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1706541.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            78204..78563
                     /locus_tag="VYO72_000086"
     CDS             78204..78563
                     /locus_tag="VYO72_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1706542.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            78617..79366
                     /locus_tag="VYO72_000087"
     CDS             78617..79366
                     /locus_tag="VYO72_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1706543.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            79356..79655
                     /locus_tag="VYO72_000088"
     CDS             79356..79655
                     /locus_tag="VYO72_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1706544.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            79726..80661
                     /locus_tag="VYO72_000089"
     CDS             79726..80661
                     /locus_tag="VYO72_000089"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1706545.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            80747..81259
                     /locus_tag="VYO72_000090"
     CDS             80747..81259
                     /locus_tag="VYO72_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1706546.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            81284..81892
                     /locus_tag="VYO72_000091"
     CDS             81284..81892
                     /locus_tag="VYO72_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1706547.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            81993..82190
                     /locus_tag="VYO72_000092"
     CDS             81993..82190
                     /locus_tag="VYO72_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1706548.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(82233..83678)
                     /locus_tag="VYO72_000093"
     CDS             complement(82233..83678)
                     /locus_tag="VYO72_000093"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1706549.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            83784..85406
                     /locus_tag="VYO72_000094"
     CDS             83784..85406
                     /locus_tag="VYO72_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1706550.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEDSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            85609..87567
                     /locus_tag="VYO72_000095"
     CDS             85609..87567
                     /locus_tag="VYO72_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1706551.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            87739..88284
                     /locus_tag="VYO72_000096"
     CDS             87739..88284
                     /locus_tag="VYO72_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706552.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            88293..88832
                     /locus_tag="VYO72_000097"
     CDS             88293..88832
                     /locus_tag="VYO72_000097"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706553.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETSFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            88868..89413
                     /locus_tag="VYO72_000098"
     CDS             88868..89413
                     /locus_tag="VYO72_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706554.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            89570..90664
                     /locus_tag="VYO72_000099"
     CDS             89570..90664
                     /locus_tag="VYO72_000099"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1706555.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            90672..91838
                     /locus_tag="VYO72_000100"
     CDS             90672..91838
                     /locus_tag="VYO72_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1706556.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            91931..95029
                     /locus_tag="VYO72_000101"
     CDS             91931..95029
                     /locus_tag="VYO72_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1706557.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGLTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            95077..95694
                     /locus_tag="VYO72_000102"
     CDS             95077..95694
                     /locus_tag="VYO72_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1706558.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            95705..97039
                     /locus_tag="VYO72_000103"
     CDS             95705..97039
                     /locus_tag="VYO72_000103"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1706559.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            97049..97513
                     /locus_tag="VYO72_000104"
     CDS             97049..97513
                     /locus_tag="VYO72_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1706560.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            97510..98004
                     /locus_tag="VYO72_000105"
     CDS             97510..98004
                     /locus_tag="VYO72_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1706561.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            98085..99740
                     /gene="mltG"
                     /locus_tag="VYO72_000106"
     CDS             98085..99740
                     /gene="mltG"
                     /locus_tag="VYO72_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1706562.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            99811..100293
                     /gene="greA"
                     /locus_tag="VYO72_000107"
     CDS             99811..100293
                     /gene="greA"
                     /locus_tag="VYO72_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1706563.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            100621..101019
                     /locus_tag="VYO72_000108"
     CDS             100621..101019
                     /locus_tag="VYO72_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1706564.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            101464..102471
                     /locus_tag="VYO72_000109"
                     /pseudo
     CDS             101464..102471
                     /locus_tag="VYO72_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            102546..102746
                     /locus_tag="VYO72_000110"
     CDS             102546..102746
                     /locus_tag="VYO72_000110"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1706565.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            102781..103497
                     /gene="atpB"
                     /locus_tag="VYO72_000111"
     CDS             102781..103497
                     /gene="atpB"
                     /locus_tag="VYO72_000111"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1706566.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQTIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            103511..104005
                     /gene="atpF"
                     /locus_tag="VYO72_000112"
     CDS             103511..104005
                     /gene="atpF"
                     /locus_tag="VYO72_000112"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1706567.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            104005..104541
                     /locus_tag="VYO72_000113"
     CDS             104005..104541
                     /locus_tag="VYO72_000113"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1706568.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            104556..106061
                     /locus_tag="VYO72_000114"
     CDS             104556..106061
                     /locus_tag="VYO72_000114"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1706569.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            106077..106955
                     /locus_tag="VYO72_000115"
     CDS             106077..106955
                     /locus_tag="VYO72_000115"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1706570.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            107041..108447
                     /gene="atpD"
                     /locus_tag="VYO72_000116"
     CDS             107041..108447
                     /gene="atpD"
                     /locus_tag="VYO72_000116"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1706571.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            108458..108877
                     /locus_tag="VYO72_000117"
     CDS             108458..108877
                     /locus_tag="VYO72_000117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1706572.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(108922..109935)
                     /locus_tag="VYO72_000118"
     CDS             complement(108922..109935)
                     /locus_tag="VYO72_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1706573.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            110079..111245
                     /locus_tag="VYO72_000119"
     CDS             110079..111245
                     /locus_tag="VYO72_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1706574.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            111235..112464
                     /locus_tag="VYO72_000120"
     CDS             111235..112464
                     /locus_tag="VYO72_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1706575.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            112610..113251
                     /locus_tag="VYO72_000121"
     CDS             112610..113251
                     /locus_tag="VYO72_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1706576.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            113261..113890
                     /locus_tag="VYO72_000122"
     CDS             113261..113890
                     /locus_tag="VYO72_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1706577.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            113903..114739
                     /locus_tag="VYO72_000123"
     CDS             113903..114739
                     /locus_tag="VYO72_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1706578.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
BASE COUNT        33812 a        21283 c        25991 g        33746 t
ORIGIN      
        1 acttaattta cgggataaaa aaaccacctt agaaaggtgt gataatgtgc aaaaagagaa
       61 tgttagaatg cgtttagcgt ctgaatccag acagatatta gataagctta aagatgatgt
      121 ttacaataaa ttaggctatg aagtaagcta ttccagtatt gttagtcaag ctgttagaga
      181 atacgttcct aaaaaagaac gtatagattg gataaaatta aaagagacag ctataccctt
      241 ttcatcgtta aaacagagca ataattggga gtaccagaca tcacttatgt tagaggaaga
      301 tgtattaatc ttactgtctg aactacaaaa ttttttctta gatgtcttcc aagcgaaacg
      361 tatacatagg gcattttgtg tacgcctatg cttgaaagca caatttttat taagtaataa
      421 tgattcttaa tactatcaat attaatgcgg agtgtaatgc tccgctaaaa taaaacctat
      481 tacgggataa aaacactact ttatttagga tggaaagagg aacgaatgaa gatgaaagct
      541 agagattcac cattgaattg attttgtttt tagaaaaaat caataattag aaaaaatacg
      601 aggtaaaaaa atgaatagag atgtattaga gtttctgaga acagagaccg ctgaaaaaat
      661 tagtctttat ataagcgagg ctaatagatt ggagggcgat gtaactctac tcgcacctag
      721 ttctcaagat ttggaagata ttaaaaatgc tatgctttcc aattctaatc tcggattaaa
      781 agttgcgaga ctggatgtga tgaagaaaat agcatatgct tctacaagaa atcattattt
      841 aacaggggct acgatttttg gggatatttc gaaaggaaca tacaattgtg atcctaaaag
      901 ttatgtctaa tataagggag gttaatccct ccccttgttt ttgaaaatcg aaaggaaaag
      961 tataaaaatg aaagttaatg aatatttctg gagaacgagc tgtcttatac taaaaaagaa
     1021 gaaatcgata aaatagtata cgtgttagag atgtgtttgt cgtaaaagtc tggatagttt
     1081 tctcctaggt agtcagctgt catataataa aaagtagaat ggcaagcagt gataattggc
     1141 ataagagatg aaaaacgctg agaactaatg aaggctaaga gaacaaaaaa tagaaaatca
     1201 atggtgagaa cccctaaata gtagaagcga atctttttat tgatttgagg ataaatctca
     1261 gcgaattgat gtttgagtcg gacgaccaag agaaatagca ggagtccttg agcaaggaag
     1321 aaaattaaac cagagagcaa gagccactca aaagatgtct cgagtctagt gataaaaaat
     1381 gcaaatagta gcaaatcaat aactgcaatt gctataaaat ggattctata gagttttttc
     1441 atgacaagac cttcctcttt tatctaactt cattctactc caaaagaatg ggagttacaa
     1501 ctaaaatgat aaaaatagca gaagggagat tctcttaagt tggctagtat tctttatttg
     1561 agtttccttc tatgtatcta acttcttcat cattccagac aaataaagct ccgattgcat
     1621 tgaggatata aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg
     1681 tcagctgaac gaaattgtaa atcaaccaaa agccccactg agttgttagt ttcaatgcat
     1741 tcaaagcatt ggcaatgagg gacagtgcaa aggcaatagt tgttacgtag gcaaggagat
     1801 tcatcttgcc ctcatatccg atatagttgg tcacaaaggc aaagaggaag gcgatgatgg
     1861 aaatgatgat ggccgccaat tttacctgtt tttggctcat ttggttgggt ctgccttctt
     1921 gcgaagcttt ccatttcttt atagcaaagg tataaatgag gaaggtgacg ggataggtaa
     1981 tgatggccgc cttatttcca aggatataat caatagcacc ggacaaaatg gtattaacaa
     2041 taccaaagta atttccccat ttgcttaatt tccccgtgaa acgagtggac aacatggaaa
     2101 tcccaacgtt ggttacggaa atcaatccaa agggtacaag agctgtccat ggtccccagt
     2161 ctacaaattt atcgaggcgt gagttgaggt aaccagatgc aatcgcaatc caacgaccaa
     2221 agcaaccccg aagaggtcaa actatttaga tgtagcaaaa atttttagtg attttttcat
     2281 aggttaaact acctttcttt ttttcaaata ttctcccacc aaatgaaagt aaaataaaat
     2341 gatagaaata aaaccctgaa aataaaactt tcagggttgg taggggactt gagaaattag
     2401 ttgattttct cgacatagag ttgttttgca atgtccatat tcacttgtaa atcctcgtcg
     2461 ttactgagga tagtgaaggt attgctgaag ccatcaaact gcttgacttg gagctggtca
     2521 ccgatgtgaa gtgagtgctt gtccagataa tggagaatgt caaaactatc gtgcacccga
     2581 gtcaggcggt aggcgccagc ttccttgata tcagctagtg ggaggttatt gatttcaacg
     2641 aggagttctc ccttggcagg aatagttcct ccgtgggggc aggttttagg gaaacctagc
     2701 agtttatcta gtctttccac gaacaggtca gagacagtgt gttccaagac ctcagcttcc
     2761 tcgtgaatct ggtcacttgt atagtctaaa tgatgaacta gaaaaacttc aatcaagcgg
     2821 tgcttacgat agagctcaga gaccagtttg agaccgaggt cagtcagtag atagccacat
     2881 tccttgtcct ttaggatgag attttcactt ttcattcgtt tgatcatttc agttacggca
     2941 gggggagaga cttgcatgcg agccgcaatt tccttgttgg taatcttatg caggtctatg
     3001 ccaatttcat aaatacattt tagatagtct tctttgtttg gggtcattcg tttcctcttg
     3061 tctaatatct ttatctagta tatcaaaaaa agctagattt ctctagctgt gactttttat
     3121 gttatactta ttgcaagaga aaaaacgagg agatggatat gacgaaaata gctcttcttt
     3181 cagatattca tggaaatacc accgccttgg aggctgtttt ggcagatgct cagcagctag
     3241 gagtggatga atactggctt ttgggagata ttctcatgcc agggacagga cgtagaagga
     3301 ttttggactt gttggatcaa ctaccgatta cggctagagt tttgggaaac tgggaagaca
     3361 gtctttggca tggtgtccgt aaggaattgg atagtactcg ccctagtcaa cgctatctct
     3421 tgcgccagtg ccagtatgtt ttagaggaaa tttccctaga agaaattgaa gtgctccaca
     3481 atcaacctct tcaaattcat cgtcagtttg gggatttgac agtgggaatt agccatcatc
     3541 tgcctgataa gaactggggg cgagagttga ttcatactgg caaacaagag aattttgacc
     3601 gcttggtgac tcatcctccc tgtgatattg ctgtttatgg acatattcac cagcagttgc
     3661 ttcgtcacgg gactggtggg caattgattg tcaatccggg ttcgattggc caacctttct
     3721 ttttggacgc tcagctacgg aaggacttgc gggcccagta tatgattttg gagtttgatg
     3781 gcaagggcct ggtagatatg gacttccgac gggtagacta cgatgtggca gctgaattgc
     3841 agctggctaa agacctgaga cttccctatt ttgaggttta ctatgaaagt ctggtcaatg
     3901 ggatccacca tactcatcat caggaatttt tgagagaatt ggctcagaaa gagggttgcg
     3961 atcgggagtt agacgactgg ttgaaaagtg gtaacgattg acattacaac taaaaagggt
     4021 ataataatag aaaaagaaga gtagaggcag ggtagcctcg taaaaaggag aagaggatgc
     4081 aaattccaag tagatttacc attgcgactc atatgctgat aatcattgcc ctcgagggga
     4141 aggaaagcaa ggtgaccagt gattttctgg ctgctagtgt cggggtcaat cctgtcatta
     4201 tcagaaagat cttgtcccag ttgaagaagg cagagctgat ttcagtagcg cgtggaacgg
     4261 gcggaacaga gattgtcaag gaccttaagg atattagtct tttagatgtt tatcaggcgg
     4321 tcgaatgtct tggtaagaca ggtcaactct tcagtttcca tgacaatccg aatccaaatt
     4381 gccctgtagg agctcatatt catgatgttt tggatcaaaa attggagaga attcagttga
     4441 ctatggaggc agaacttggt cagaccagtc tagaaaaagt cgtggccgat gcagagagtc
     4501 agatgaagga ttaagaggga taaatgccct ctttttttct ttggataatt atgataaaat
     4561 gtagctatta aaggagtaag aaatgtatct cgttatagaa attgtattag cctttatagt
     4621 gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat tatccctcat
     4681 ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga atgttcagtt
     4741 agctttttat gtatttacct ttgtcttact tccttttttg ctttttctaa gtggcatctt
     4801 tttaatctat aatggggtca ttttgttgaa acgagaggga cgttccaagc cccattatct
     4861 ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact tagaatgcac
     4921 atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa gagtattatc
     4981 tatttttcca tgcatggtaa cgagtatcaa tcaataactg ggtaaggcga cccaaggttt
     5041 ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg tattcaagcg
     5101 cctttaagga agccaagtca ttgatagagc taataccagc atcaagaata gtgccaaaga
     5161 agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat tctttaaagg
     5221 ttgtgtctac ttgccggcta tcactgttgg tcttatccag ttgaacgaag tgcttgtcct
     5281 caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta ctctgaacga
     5341 tgatttggtg agcaggaatt tccagcatca taccgataat agacccttgt ggaatgaata
     5401 tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct tgatggagac
     5461 caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc tcaatttggc
     5521 tagcagcata gatagcgaga tttcctccct tggaatgccc agccagaata accttttgct
     5581 taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga gcaggaattt
     5641 ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca tctgtcccac
     5701 gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca aattgctttt
     5761 gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg aagcgcttgt
     5821 gttgagccaa ttcatctaat aattgaaggc gatttttgct agtaagcatg gtgggctctc
     5881 ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc agattatcaa
     5941 aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag ggaaggtcgt
     6001 aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata agagctcctt
     6061 tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc ctgtttgtac
     6121 tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga aaaatctgtt
     6181 ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga tgatcaggtc
     6241 attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt cctggtagaa
     6301 gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt cctcatggat
     6361 attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa gatttccaag
     6421 gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat ggcaatcaat
     6481 atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt agctaaggtt
     6541 cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct ggaatatgct
     6601 ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt cttgaatttg
     6661 accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa catcgtagca
     6721 cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga taataccctc
     6781 tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt aggatttatc
     6841 gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac aattttttct
     6901 agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttttttgg catttcttgt
     6961 cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact ttttcttctt
     7021 gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa cgcaggtcta
     7081 tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa tagctttagc
     7141 agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag cagaaagaaa
     7201 actgacggat ttgctggatt actatacctt gtgggttcat cagataaaga cccccattgc
     7261 agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc agctagaaca
     7321 ggaaattttc aaaatcgact cctataccaa cctagtttta cagtacctgc gtttagaaag
     7381 tttccatgat gatttggtct taaagcaggt tcaaattgag gacttggtca aggaaataat
     7441 tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac atgaccttga
     7501 taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa tcatctcaaa
     7561 cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc aagagctttg
     7621 tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat ttgaacgtgg
     7681 cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc tttatctatc
     7741 taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg tcggaaaagg
     7801 aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa aatagatgag
     7861 aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg cgtgatttgt
     7921 tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt tgtgtttctt
     7981 tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct ccaacaatta
     8041 attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt ttttcattgc
     8101 gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggccact tcccaagcgt
     8161 agttcacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt gccagccatg
     8221 ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc atagttgaga
     8281 taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg atgtatttga
     8341 ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt tcttcttttc
     8401 caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct tcaccttcgg
     8461 cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt tgggcatttt
     8521 cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga agagagaggc
     8581 ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac tgaagggcac
     8641 gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg ttgagtgaca
     8701 tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg tgcatcatac
     8761 cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt ttgaaaactt
     8821 ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca cccatgtcca
     8881 tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg taaagctcaa
     8941 cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct ttgtttacga
     9001 tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat ggcaaacctt
     9061 gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta cggtggtcac
     9121 gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg tcaaaccaag
     9181 ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag taagcaccag
     9241 ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga ggtccacggc
     9301 agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct tctgagtgtt
     9361 cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc tcgtctttag
     9421 tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt tcttcttcga
     9481 tacgaggaag gtcttcgtta gagatttgac cagctatgtt gtcagtatcg tagtagaaac
     9541 catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga cgagctgctt
     9601 gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatcttcg tgatcaggtg
     9661 tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg agtttgccgt
     9721 tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg gcaatttcaa
     9781 aagttgttac gccagattcg aattcacgaa cagcgccatc tgggaaagta atgttaatca
     9841 tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta tcagcagact
     9901 acttccaagt cctaacgttc aattgctttt ctttatcaga gaggaagttt tccatttccg
     9961 tcagaatgtc tatatccaaa cgttgagaaa gttctaatag ccaccagata ttttctgaaa
    10021 gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt gtcatcacca
    10081 atcgttggaa atttccaata tcattagata aagccaagag gtcttcttct accgtccact
    10141 tggaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc caactgtgct
    10201 ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac atcctcgaaa
    10261 ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg acacctctga
    10321 tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt agtatcagtt
    10381 tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga ctaagtgact
    10441 tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg tgaaagtttt
    10501 ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat gcccaccaga
    10561 gcaactgttt catagattag caagtaaatt agtataaact caccaaagat tatgatagtg
    10621 aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa acggtagcta
    10681 tagagtaacg atacaatcaa gattaccaga ggtgtaaaga agagaagatt gtttatatag
    10741 agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata aagtggccaa
    10801 taaatatgac cagatagtag gggagatggg aatagaatct acgcatgata atcacctcgt
    10861 tttaaaaaaa acagacaact tagatctctt gctatgatta ttataagcat gtttaaaaca
    10921 agaaagtaaa tttgttgaca aagaagattt ttcttttcac tagaatcata gttagttttc
    10981 ttggtagaaa tattttgata ataattaagc aagactattg acattgatta ttaagagtgt
    11041 cacaattgct gtaactaaaa taattacaac aagagaggta taaaaaatga aactagcagt
    11101 tattgcagca aatggacaag tggggaaagc aattgttgaa gaagcagtca aacgaggaca
    11161 tgaagtaacg gctattgttc gttctgaaaa caaaagtcaa gctgagtcta ttattaaaaa
    11221 agatttattt gagttgacaa aagatgatct tactggattt gatgctgtta tttcagcgtt
    11281 tggtgcttat acaccagata cgctaccgct ccatagcaaa tcaatcgaac tatttaatca
    11341 gcttcttgct ggaacacaga cacgttttct agttgtaggg ggagcagaaa gtctttatat
    11401 agatgaaaca aaaacgacac gacttttaga tacgtctgat tttcctgaag aatttaagtc
    11461 actagcaaaa gctcaagcgg atgaattgga tcttcttcgt acaaaaaata atctcaactg
    11521 gacttttgtc agtcctgctg tagattttat tcccgatggt gaaaaaacag gaaactacat
    11581 tctagcagga gaaattttta ctactaatga aaaaaggaat aagccagatt agttatgcag
    11641 attatgctat tggattggta gatgaacttg aaaaaggtca tcatataaaa gaacgtatct
    11701 ctttacttga aaaataataa ctatgagagt attaatgttt gacagaaaat ttaaatcttg
    11761 gtaaaatagg gattgtcgta aagacaaata acttcttctt ggttacaggc atgccaacct
    11821 gtcactcgga tgaagccaaa taaaaaggag aaacatcatg gcaatctcaa aagagaaaaa
    11881 aaatgaaatc attgcacaat atgcacgtca cgaaggtgat acaggttcag tagaggttca
    11941 agttgctgtc cttacttggg aaatcaacca ccttaacgaa cacatcaaac aacacaaaaa
    12001 agaccacgct acttaccgtg gattgatgaa aaaaatcggt cgtcgtcgta acttgcttgc
    12061 atacttgcgt aaaaacgacg ttaaccgtta ccgtgagttg atcaactctc taggacttcg
    12121 tcgctaattc aagatacaaa ggccgtcaaa agcacaaagc aaaaatagga aaattgacga
    12181 agaaacttca gtttctagga gattttatct tttttgccaa gtgcttaggc cgtgttcaat
    12241 tgagcatatc ttgataataa agctactcta aattgggtag cttttttgcg ttgtcacctt
    12301 acctcgctat actcaagtat aatctttggt tacggttcct agcactgtaa ggtaaaataa
    12361 accagctttt ctcccttcgg ggagattttt tttgtttcac tgaaagtttc gtacgatctt
    12421 cgcctcgtcg cctagtctat aaacgattta tctagcaaga atcatgatgc taagggcgtc
    12481 aaaaatccgt atgaaaatag ggaaatgaca cagtgttcga tgagcacaag gagtttcatc
    12541 tttttcacta ggattttagc ccgggctaaa atcagctctc tgacttcaga gggctttttt
    12601 attgaggttt tatcggtaac aattttggag actacaaaaa cctcaaatgg tatcagctaa
    12661 ttacaccata aaggtgcgca gttactcggc ttttcaagcc gagtagctgt atgcaagccc
    12721 cctagaagag cccactcttt acaaagtaaa gtatagtatg ttatacttta catggaagta
    12781 gtcactgaat tccagttaga aattactttg taactacgtt ttgaggagga gtaaaatgct
    12841 ttcctacgtt cgacattacc cactagcgat agctaaatta atgtgtctgt gctctcctga
    12901 aatctgctga tttattactg actaatacag gaggtttttt ttatgggaca gacaatcata
    12961 tctgctattg gtgtttatat ttccaccagt atcgattatt taattatttt aattatttta
    13021 tttgcacagc tatcacagaa taaacagaaa tggcatattt atgcggggca atatctaggc
    13081 acaggcttac ttgtaggggc gagtttagtt gctgcttatg tcgttaattt cgtgcctgaa
    13141 gaatggatgg ttggattgct tggtttaatc cctatctatt tagggattcg ctttgcaatt
    13201 gttggagaag atgcggaaga agaagaggaa gaaattattg aaagattaga acaaagcaag
    13261 gcaaatcaac tgttttggac agttacattg ctgacaattg cgtctggcgg agataattta
    13321 ggtatctata taccttattt tgcttcgtta gattggtcac agaccctcgt ggccttgctt
    13381 gtgtttgtaa tcggcataat tatcttttgc gagattagtc gggtgttatc ctctattccg
    13441 ttaatattcg agacaattga aaaatacgag cgaatcattg tgcccttagt attcattcta
    13501 cttggactat acatcatgta tgaaaatggc acgatagaga cttttctgat cgtgtagatt
    13561 tttttgtttc actaggattt tagcccgagc tcaaatcagc tctctgattt tcagagggct
    13621 ttttcattga gtataaatgg acaatcttaa agttactcta ttgtagagtg gcttttgatt
    13681 tgattaggag attcttataa atatagtaaa atgaaacaaa aacaggacaa atcgatcagg
    13741 acagtcaaat cgatttctaa aaatgtttta agaagtagag gtgtactatt ctagtttcaa
    13801 tttgctatat aaatgaaaac cttagctgtt tggccaaggt tcatttcttc tatgcaagtt
    13861 cttctctttt cttatctggg ttccagatga agcttgcgat aaagctaaag atgatggtta
    13921 ggatagcgag gataatagca aggatgaggg cagggatgcg gataaaccac cagagtggat
    13981 ttggtttttt atcattgtgc cattgtttcg tttcttcgtc cagacgttgg aattctgttt
    14041 gaatacgatt ggcgactgtt tcaatgcctt catcattcat tttcttgata tctgagatat
    14101 cgattggatt tccaaagttc atatcgacac gttcacggct aatcaagccc ttcaaaatca
    14161 tgggaccggt gtaggtaacc ggcatgatac ggaccttggc cattttggca atcagtgctg
    14221 cgcccccctt gacatcgttt gagtggcggc taccacttgg aaacatgatg agagagcggt
    14281 cacttttttt gagaacgttg ataggatatt tgatggctga ggcgctggga ttttcacggt
    14341 cgatgggaaa ggcgccacac atacgaatcc accaaccaaa gatacggttg gtaaagagtt
    14401 ctttttttgc cataaagatg aactgttttg gcttggtcgc aaaggccata taaacaggat
    14461 cccaccaggt acggtgaggc gcaactaaaa tataattttc atcttgatta ggaattttat
    14521 cagtattatg atagtgagca ttgccattga tggaccataa gagcaacaca actaatccac
    14581 gcaaataagt ataaaacatg cgatctcctt cgattgtttt cttgttatta ttatacctta
    14641 tcaaaggagg gctggcaaac ttttcccttg actagatgca tatttgggat gaaattagaa
    14701 ttctgttaaa aaaaatggta taatagaatt tatggataaa aataagatta tgggattaac
    14761 ccaaagagaa gtcaaggaaa gacaggctga gggtttggtc aatgacttta ccgcatcagc
    14821 cagtaccagc acttggcaaa tcgttaaacg aaatgtcttt acccttttta acgctttgaa
    14881 ctttgccatt gctttggccc ttgcctttgt gcaggcttgg agcaatctgg tcttctttgc
    14941 tgttatctgc tttaacgctt tttctgggat tgtgaccgag ctacgagcca aacacatggt
    15001 ggacaagctc aatctcatga ccaaggaaaa ggtcaaaacc atccgtgatg gtcaggaagt
    15061 tgctcttaat cctgaagaat tagtgctagg agatgtcatt cgtttgtctg caggagagca
    15121 gattcctagt gatgccttgg ttttggaagg ctttgcggaa gtcaatgaag ccatgttaac
    15181 gggagaaagt gatttggtgc aaaaggaagt tgacggctta cttttgtcag gaagtttcct
    15241 agccagtggg tcagttttat ctcaagttca ccatgtcggt gcagacaact atgctgccaa
    15301 actcatgctt gaggctaaga ccgttaaacc catcaactcc cgtatcatga aatcgctgga
    15361 caagttggct ggttttactg ggaagattat cattcccttt ggtctggctc tcttgctgga
    15421 agccttgctt ttaaaaggcc tgcctctcaa gtcatccgtt gtaaactcgt cgacagctct
    15481 tttgggaatg ttgcctaagg gaattgccct tttgaccatt acttcgctct tgactgcagt
    15541 gattaagttg ggcttgaaaa aggtcttggt gcaggagatg tactctgttg agaccttggc
    15601 gcgcgtggat atgctctgtc tggacaagac gggcaccatc acccaaggaa agatgcaggt
    15661 ggaggctgtt cttccactga cggaaactta cggtgaagag gctattgcca gcatcttgac
    15721 tagctacatg gcccatagtg aggataagaa tccaactgcc caagccattc gccagcgttt
    15781 tgtgggagat gttgcttatc ctatgatttc caatcttccc ttctcgagcg accgcaagtg
    15841 gggggctatg gagttagaag gcttggggac agttttctta ggggcacctg agatgttgct
    15901 ggattctgaa gtcccagaag ccagggaggc cttggagaga ggatcacgtg tcttggtctt
    15961 agctctcagt caggagaaat tagaccatca caaaccacag aaaccatctg atattcaggc
    16021 tctagccttg ctggaaatct tggaccccat tcgagaggga gcagcagaga cgctggacta
    16081 tctccgttct caggaggtgg gactcaagat tatctctggt gacaatccag ttacggtgtc
    16141 cagcattgcc cagaaggctg gttttgcgga ctatcacagc tatgtagatt gctcaaaaat
    16201 caccgatgag gaattgatgg ccatggcgga ggagacagct attttcggac gtgtttcccc
    16261 tcatcaaaag aaactcatca tccaaacgtt gaaaaaagcg ggtcatacaa cggctatgac
    16321 aggggacggg gttaatgata tcttggccct tcgtgaggcg gattgttcta tcgtgatggc
    16381 ggagggggat ccagcaaccc gtcagattgc caatctggtt ctcttgaact cagactttaa
    16441 tgatgttcct gagattctct tcgagggtcg tcgcgtggtc aataacattg cccacatcgc
    16501 cccgattttc ttgataaaga ccatctattc cttcctgtta gcagtcatct gtattgccag
    16561 tgctttacta ggtcggtcag agtggatttt gattttcccc ttcattccga tccagattac
    16621 catgattgac cagtttgtgg aaggtttccc accattcgtt ctgacttttg agcgaaatat
    16681 caaacctgtt gagccaaatt tcctcagaaa atccatgctt cgtgccctac caagcgctct
    16741 catggtcgtc ttcagcgtcc tgtttgtgaa aatatttggg agtagccaag gttggtctga
    16801 gttagaaatc tcaactctac tctattatct cttggggtca attggtttct tatccgtatt
    16861 tagagcctgc atgccattta ccctatggcg tgtcctcttg attgtttggt cagtaggagg
    16921 tttcctagcc acagctctct tcccaagaat tcaaaaactg cttgaaattt caaccttaac
    16981 aggacaaaca ttacctgttt atggtgtcat gatgttggtc tttaccgtga ttttcatcct
    17041 gaccagtcgt taccaagcga aaaaataaag aaagactgca atctgtggat tgcggttttt
    17101 ttaggtacaa gattgccagc cgaaatgtgg tataataaga ggtaatagag tttggaaagt
    17161 gagagaaaat gatttcaaag agattagaat tggtagcttc ctttgtgtca cagggggcta
    17221 ttttactaga tgtgggaagt gaccatgctt atctgcctat cgagttggtt gagagaggcc
    17281 aaatcaaaag cgctattgca ggtgaggtgg tggaaggtcc ctatcagtct gcggttaaaa
    17341 atgttgaggc tcacggccta aaggagaaaa tccaagtccg tttagccaat ggcttggcag
    17401 cttttgaaga gactgaccaa gtgtctgtca ttaccattgc tggcatgggt ggtcgtttga
    17461 ttgctaggat tttagaagaa ggtttgggga agttagctaa tgtagagcgt ttgatcctcc
    17521 agcccaataa tcgtgaagac gacttgcgta tctggctaca ggatcatgga ttccagattg
    17581 tagcagaaag catcttagaa gaagctggaa agttttatga gattttggtg gtggaagcag
    17641 gacaaatgaa gctatcagcc agtgatgttc gctttggtcc cttcttgtcc aaagaagtca
    17701 gtccagtatt tgtccaaaaa tggcaaaaag aagctgagaa gctagagttc gccctcggac
    17761 aaatcccaga aaaaaatctg gaagaacgtc aagttctagt agataagatt caagctatca
    17821 aggaggtgcc ccatgttagc aagtgaagtg atccaagctt atgaagcctt ttgccctcag
    17881 gaattttcta tggagggaga cagccgtggt ctgcaaattg gcactttaga caagggtatc
    17941 caaagggtca tggttgccct cgatattcgt gaagagacag tggcagaggc cattgaaaag
    18001 ggtgtggact tgattatcgt caagcacgcg cctatctttc gtcctatcaa ggacttgctt
    18061 gccagccgtc cgcaaaatca gatttacatc gacctgatta agcatgatat cgcagtttat
    18121 gtcagccata ccaatattga tatcgttgaa aatgggctca atgactggtt ttgtcagatg
    18181 ctaggaatcg aggagacgac ttatctgcag gaaacaggtc cagaacgtgg aattggacgt
    18241 attgggaata ttcagcctca gacattttgg gaattggccc aacaggtcaa gcaagtcttt
    18301 gacctagata gccttcgaat ggtgcattat caagagaatg atttgcagaa gcctatttca
    18361 agagtagcaa tttgtggtgg aagcgggcag tctttctata aggatgcttt ggcaaagggg
    18421 gcagatgtct atatcactgg tgatatctac taccatactg ctcaggatat gctgtctgat
    18481 ggcttgttag cattggatcc aggtcactat atcgaagtgc tttttgtgga aaaaatcgca
    18541 gcactcctta ctcaatggaa agagaaaaaa ggctgggaac tagagatttt acctagtcaa
    18601 gcatcgacca atcctttccg tcatatctag ttagaaagtg aagacaatga aaaaagttgc
    18661 cattattgga gcaggaattg tgggagcaac agctgcctac tacctctcga gagaaagtga
    18721 cctagaggtg accgtttttg accatgagca aggtcaagcc accaaggccg cagcaggaat
    18781 tatcagtcct tggctttcaa aacgccgcaa taaggcctgg tacaagatgg cgcgattggg
    18841 ggctgacttt tatgtggatt tattagctga tttagagaaa tcaggacaag aaatcgactt
    18901 ttaccagcgt tcgggagtct ttctcttgaa aaaggatgaa tccaagttgg aagaactcta
    18961 tcaactggct ctccagcgca gagaagaatc tcccttgata ggccagttat ccattctgga
    19021 ccaagcccca gctaatgaat tattccctgg cttgcaggga ttcgacaact tgctctatgc
    19081 ttctggtgga gcgagagtag atggtcacct cttagtaact cgtttgctgg aagccagtca
    19141 ggtcaagttg gtcaaagaaa aagtgactct gacactctta tcatcaggct accagattgg
    19201 cgaagaggtg tttgatcagg ttattttggc aacgggagct tggttggggg acatgttaga
    19261 gcctttaggt tatgaagtgg atgtccgtcc tcaaaaagga caactacgag attatcagct
    19321 tgcccaagac atggaagatt accctgttgt catgccagaa ggggagtggg atttgattcc
    19381 ctttgcaggt gggaaattat ccttgggcgc tacccatgaa aatgacatgg gatttgattt
    19441 gacggtagat gaacccttgc tccaacaaat ggaggaggcg gccttgcctc attacccagt
    19501 tttagctaga gtgacttcaa gggctgagcg tgtgggaatc cgtgcctata ccagtgattt
    19561 ctctcccttc tttgggcagg tgccagaatt ggcaggtgtc tatgcagcca gtggactagg
    19621 ttcatcaggc ctcacaactg gtcctatcat tggttaccat ctagcccaac tgatccaaga
    19681 caaggagttg accttggacc ctgaaaacta cccaattgaa aactatgtca aacgagtaaa
    19741 aagcgaataa tactcaatga aaatcaaaga acaaactagg aaactagccg cggattactc
    19801 aaagcactgc tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga
    19861 ggttgtggat agaactgacg aagtcagtaa ccatacccat ggcaaggcga cgttgacgtg
    19921 gtttgaattg gattttcgaa gagtataagc attttactga aattttatca ggtagtttag
    19981 gatggcaaat gacattccct gtcaaaaatg gtaaaataag aaaaaataat ctgagaatcg
    20041 aggaaaaaag atgcaagaaa agattttggt aactggtggt gccggtttta ttggaaccca
    20101 cactgttatt gaattgatcc aagcaggcca tcaagttgtt gtggtggata atcttgtcaa
    20161 tagcaatcgt aagagtttag aagttgttga aagaatcaca ggagttgaga ttcctttcta
    20221 tgaggcagat attcgtgaca cagataccct cagagatatt ttcaagcagg aagaaccgac
    20281 tggtatcatt cactttgctg gtttgaaggc tgttggcgaa tcaacacgta tccctcttgc
    20341 ctactatgac aacaatatcg ctggaactgt cagccttttg aaagccatgg aagaaaacaa
    20401 ctgtaaaaac atcatcttca gttcttctgc gacagtttac ggggatccgc acacagtgcc
    20461 catcttggaa gatttcccac tttcagtgac caacccatac ggtcgtacta agctcatgct
    20521 agaggaaatt ttgactgata tttacaaagc agactcagaa tggaatgttg tcttgcttcg
    20581 ttactttaac ccaatcggag cccatgagag tggtgatttg ggagaaaatc caaacggtat
    20641 tccaaacaat ctcttgccat atgtgactca agtagccgtt ggaaaattag agcaagtgca
    20701 agtgtttgga gacgattacg atacggaaga tggaacaggt gttcgtgatt atatccacgt
    20761 tgtcgatttg gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag gttcaggact
    20821 aaacgtttat aaccttggaa ctggtaaagg ttactcagtt cttgaaatta tccaaaacat
    20881 ggaaaaagcg gtgggacgtc ctattcctta ccgcatcgta gaacgtcgcc caggtgatat
    20941 cgctgcctgc tactcagacc cagcaaaagc taaagcagaa ctcggttggg aagcagaact
    21001 cgacatcacc caaatgtgtg aagacgcatg gcgttggcaa agcaagcatc caaatggatt
    21061 tgaagactaa gatgatgatt tcaatcatcg tcccttgttt aaacgaagag gaagtacttc
    21121 ctctttttta tcaggctctg gaagctttac ttccagattt ggaaacagaa atcgagtatg
    21181 tctttgtcga tgatggatca agtgatggga ccttggaact cttaaaggcc tatcgggagc
    21241 aaaatccggc agtccattat atttctttct ctcgaaattt tggcaaagaa gcagcccttt
    21301 atgcaggctt gcaatatgcg acaggagatt tggtggtggt gatggatgca gacctccaag
    21361 atcctcctag tatgttgttt gagatgaaaa atgtactaga caaaaatgta gacttggact
    21421 gcgttgggac acggagaact agtcgggagg gagaaccctt ctttcgcagt ttctgtgctg
    21481 ttctctttta tcgcctcatg caaaaaatca gcccagtagc tctgccgtcg ggtgtccgtg
    21541 attttcgtat gatgagaagg tctgtagtcg atgccatttt aagcttgacc gagtccaatc
    21601 gtttttcaaa ggggctcttc gcctgggtgg gtttcaaaac ctactatttg gactatccaa
    21661 atgtcgaaag gcaggctggc aagacaagtt ggagttttag gcaactcttt ttctactcca
    21721 ttgaagggat tattaatttt tcagattttc ccttgattat agcctttgta gctggtctcc
    21781 tatcttgttt tctttctctg ctgatgacct tttttgttgt ggttcggacc ctcattttgg
    21841 gcaatccgac atctggttgg acctctctga tggctgttat tctctttctt ggaggcattc
    21901 aactcttgac cattgggatt ctcggcaagt atatcagtaa gatttattta gagactaaaa
    21961 aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata
    22021 aagtgaaaag actataattt tacatggaaa tgtgctaaac tagagggagt ggattatcgc
    22081 cattgattta ggcttcctgg tttccaatca gggcgcgcgt tgggcaattt ttaacagcct
    22141 ctaagacatc ctgactagga gaaatttctt tttccagttg gtcagggtca tcgtaaaaac
    22201 gcacgattcc attatcgtgg taatcaaata aatcagaata agtttggcaa agcccacagg
    22261 cgatacatcg ttcaggtata agtgtgattt tcatgttcat atttatattg taataagaaa
    22321 agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg tggcaagaag atatctatga
    22381 tcaagaagaa tcaagagcag agcgtcggca tcgaaaccac ggaggggctg ataggatggc
    22441 taatcgtatt ttgacgatcc tagctagtat tttctttgta attgtggtgg tgatggtcat
    22501 cgttctcatc tatctatcat cggggggaag taatcgcaca gcagccttaa aagactttca
    22561 tgattctgat gcaagtgtag tacaaatctc atcttcaagc agttctcagc ctgagcagag
    22621 ttcagagcca gaatctactt ctagtagttc agaagaagct gctaatcctg aaggaacgat
    22681 taaagttctc gcaggagaag gggaagcagc tattgccgct cgtgcaggaa tctccattgc
    22741 tcagttagag gccttgaatc ctgggcacat ggctacagga tcttggtttg ctaatccagg
    22801 tgatgttata aaaataaaat aggagccgat atgaaaacaa ttcaaattgc tattgatggt
    22861 cctgcttcca gcggtaagag tacggtcgca aagattattg ctaaggattt tggattcacc
    22921 taccttgata caggagctat gtatcgtgca gcgacctata tggctcttaa gaaccaatta
    22981 ggagttgaag aagtcgaagc ccttctagcc ttgttggacc agcatccaat cagctttgga
    23041 cgttcagaaa ctggagacca gcttgttttt gtaggagatg tggatattac ccatcctatc
    23101 cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag caattcctga agtgcgtgag
    23161 aaactggttt ctctccaaca agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc
    23221 gatattggaa ctgttgtatt gccacaagca gaattgaaaa ttttcctagt agcttctgtt
    23281 gatgagagag cagagcgtcg ttacaaggaa aatattgcca agggaattga aacagacctt
    23341 gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg atagtcatcg tgagacttct
    23401 cctctcaaac aagcagagga tgctgtctac cttgatacaa ctggtttgaa cattcaagaa
    23461 gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt aaatgtagaa aagccgatag
    23521 attgatatcg gttttttcta aatttgtcaa aatgctgatt ttagggtata atagttgctg
    23581 ttcgagaaat tttgattttc aaagaatagt gaatgatgat aaggagaaat catgaacaat
    23641 ttaccaaatt gtccaaaatg taactcagag tatgtctacg aagacggtgc cctactggtt
    23701 tgcccagagt gtgctcatga gtggaatcct gctgaagttg cagaagtaga agaaggtctt
    23761 gtcgctatcg atgccaacgg aaataaattg gctgatggtg atacagtaac tctcatcaag
    23821 gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag ggacgcgcgt gaaaaatatc
    23881 cacatcgtag aaggcgacca caatatcgac tgtaagattg atggttttgg tgccatgaaa
    23941 cttaaatcag agtttgtgag gaagatttaa gcatgtcaaa acactataaa cttgtatttt
    24001 atagccgtat cttcttgttt ctagcggctt ttacgggagt ttatcttgaa attactaagc
    24061 atggtggttt tgggatgctt ctctattaca cggttctgtc caacctcttg gtaactattt
    24121 ttacccttta tcttctaaag gttatgagcc gtgtaggtga aaattggcaa agaccaagtc
    24181 tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat tacctgtgtg atttaccatt
    24241 tcctcttggc gcccattgcg actaatttct ataccctaga aaatttcctt tgccactata
    24301 tcgttcccat ctggttttta gcggataccc tcttttttga caaacagggt caatacaaga
    24361 tttgggatcc agcagtgtgg accattttac cctttctgta tatgatgttt gctcttttta
    24421 atggcttggt tctaaaactc aatattccaa atgccaagga taatcctttc ccttacttct
    24481 ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg gtgtctgatt atctttgttg
    24541 cctatatggt agcaggattt attttctact ttatcaagca aatcaagaga aagtcatcct
    24601 aatactcttc gaaaatctct tcaaaccacg tcagtttcca tctgcaacct caaaacactg
    24661 ttttgaacaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagat
    24721 acaagggatt cattttcgaa tttaagaagg agtctacaaa ccaatgaggc ttcttctttt
    24781 cttgcttatt tgataactat caaaaaagta gaagattaag agaaatatag aaagagattt
    24841 catgaaacaa tttttagaac gggccagcat tttggctctc tccctcgttt tgattacctc
    24901 cttttccatt tcgagtgccc taccagccat gtttgactat tatcagggtt attctaagga
    24961 acaaattgag ctcttggtga gcttgccttc ctttggaatc atgatgatgt tactgctaaa
    25021 tggtttctta gaaaaaatat ttcctgagcg cttacagatt agtttgggct tgctgatttt
    25081 atcattgagc ggtacagctc ccttctggta ccaagcctat ccctttgtct ttggagcacg
    25141 gcttctcttt ggtttgggtc ttgggatgat caatgccaag gccatttcta ttatcagtga
    25201 acgctaccaa ggaaaaaggc gaattcagat gttagggcta cgcgcttctg cagaggtcgt
    25261 tggagcttct ctcattacct tggccgtcgg tcagttgttg gcctttggtt ggacagctat
    25321 ctttctagcc tatagtgctg gatttttggt gctgcccctt tatctgctct ttgtccctta
    25381 tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa gcaagtcgtt taactcgaga
    25441 aatgaaaggc ttgattttta ccttagctat cgaagcggca gttgtagttt gtaccaatac
    25501 agctattacc atccgtattc caagtttgat ggtggaaaga ggattggggg atgcccagtt
    25561 atctagtttt gttcttagta tcatgcagtt gatcgggatt gtggctgggg tgagtttttc
    25621 tttcttgatt tctatcttta aagagaaact gctcctctgg tctggtatta cctttggctt
    25681 ggggcaaatt gtgattgcct tgtcttcatc cttgtgggtg gtagtagcag gaagtgttct
    25741 ggctggattt gcctatagtg tagtcttgac gacggtcttt caacttgtct ctgaacgaat
    25801 tccagctaaa ctcctcaatc aagcaacttc atttgctgta ttaggctgta gtttcggagc
    25861 ctttacgacc ccatttgttc taggtgcaat tggcttacta actcacaatg ggatgttggt
    25921 ctttagtatc ttaggaggtt ggttgattgt aatctctatc tttgtcatgt acctacttca
    25981 gaagagagct taggattgat tcctaagttt ttcttttgat actcaatgaa aatcaaagag
    26041 caaactatag ttgattgagt ttggaatagt acgctgtagc tgctaaaata tttctagaaa
    26101 ttaatttgac tttcctaata gagttattca tatcttattt caatctacta tagaaagcta
    26161 gccgcaggtt gctcaaaata gtgttttgag gttgcagatg gaaactgacg tggtttgaag
    26221 agattttcga agagtatgag atttttatac ccatacaata tttgttttag gtccttgttt
    26281 acagactaat ttcttgataa aatagaggtt atgacgagat ataaagcaac tatttcctat
    26341 gatggttatg cctttgctgg ctttcagcgc cagtctcatg cgcgtagcgt tcaggaagaa
    26401 attgaaaaaa ccttgaccag attaaataaa gggcaagcca ttactgttca cggtgctggt
    26461 aggacagata gtggggttca tgccctggga caggtcattc attttgacct gccttatcag
    26521 attgatgagg agaaactccg ttttgccttg gatacccagt ctcctgaaga tattgatgtg
    26581 atttcgattg agcttgtggc agatgatttt cattgccgtt atgccaagca tagcaagacc
    26641 tatgagttta ttgtggatag aggacgtccc aaaaatccga tgcgccgtca ctatgccacc
    26701 cactttccct acccactcga tgtggaacga atgcagattg caatcaaaaa gctagaggga
    26761 acccatgatt ttaccggttt tacagcctct gggactagtg tagaggataa ggttcgcacc
    26821 atcacagaag ctagtttaat agtcgatgag acaggacaat ttttgacctt taccttttcc
    26881 ggaaatggtt tcttgtataa acagattcgc aatatggtgg ggactcttct caaaatcggt
    26941 aacaaccgca tgccagtaga gcagattgat ctcatcttgg agaagaagga caggcaactt
    27001 gcaggtccca ctgcagcacc aaatggtttg tatttaaagg agattcgtta tgaagaataa
    27061 tcgtatttta gcactttctg gaaatgatat ttttagtggt ggtggactgt cagctgattt
    27121 ggctacctat accttgaacg gcttgcatgg gtttgtagca gtgacttgtt tgacagcctt
    27181 gacagaaaaa ggatttgaag tctttccaac tgatgatacc atttttcaac atgaattaga
    27241 tagcttgcgt gatgtggaat ttgggggaat taagattggt cttctcccta ctgtcagtgt
    27301 ggctgagaag gccttggact ttatcaaaca acgcccagga gtacctgtgg tgttggatcc
    27361 tgtcttggtc tgcaaggaaa cgcatgatgt agctgtcagt gagctctgcc aagagttgat
    27421 tcgctttttc ccttatgtca gtgtgattac gcctaatctc ccagaagcag aattattatc
    27481 cggtcaggaa attaaaacct tggaagacat gaaaactgca gcgcagaaat tgcatgattt
    27541 aggagcgcca gcagtcatta tcaagggagg caatcgtctt agtcaggaca aggctgtgga
    27601 tgtcttttat gatggacaga cctttactat cctagaaaat ccagttatcc aaggccaaaa
    27661 tgctggtgca ggttgtacct ttgcctctag cattgccagt cacttgatta aaggtgataa
    27721 acttttgcca gcagtagaaa gctctaaggc tttcgtttat cgtgctattg cacaagcaga
    27781 tcagtatgga gtaagacaat atgaagcaaa caaaaacaac taaaatcgcc cttgtatccc
    27841 tattaaccgc cctttctgtg gttctaggtt atttcttaaa aatcccaaca cctacaggaa
    27901 ttctaactct tttagatgct ggtgtcttct ttgcggcctt ttactttggt agtcgtgaag
    27961 gagcggtagt cggaggacta gcaagtttct tgattgacct cttatcaggc taccctcagt
    28021 ggatgttctt tagcttggtc aaccatggct tgcagggatt tttcgcagga tttaaaggaa
    28081 aaagtcagtg gttaggcctt attttagcaa ctattgccat ggtaggaggc tacgccttgg
    28141 gttctacttt gatgaatggc tgggcagcag ccctcccaga aattctacca aatttcatgc
    28201 aaaatatggt agggatgatt gtaggattta ttcttagtca aagtatcaag aagattaagt
    28261 aatactcttc gaaaatctct tcaaaccacg tcagtttcca tctgcaacct caaaacactg
    28321 ttttgagcag cctgcggcta gctttctagt ctgattttca ttgagcataa agaggttgag
    28381 taaaaagtct ttcaaataag aaaaacgcat agtatcaggt gttgaatgaa cacctgatac
    28441 tatgcgtttt attgtgggaa gattttcctc attttctagt gaaattgaac tttttctaac
    28501 atcttttgat agatgacttc ttaatcaatt atcatttcca ttgttgtttc ttggggtttc
    28561 atcccttgtc tttgataaaa gcggagagca ccctcgttat cattccagac acttagggtt
    28621 agattattgc agccaatttc tttagcataa tagcagaaaa atgacaataa aatagcccct
    28681 agatattttg aaaggaaagc ataggggcta tatagtttaa tcaaaataaa gcaaatcttt
    28741 gctggtgctt gtaaagaggt cgaagccatc cttggtaaca acaccgcagt cttcaatacg
    28801 aacaccgact ttaccaggga tatagatacc tggttcaaca gagaagcaca tgccttcttc
    28861 gatgaccatg tcgtttcctt ccatgataga tgggaattca tggacatcca taccgatacc
    28921 atgcccgaga cggtggttga agtactcacc ataaccagct ttttcgatga cctcacgggc
    28981 agcgcggtcc acttcatgag cagtcacacc tggcttgata aagtcaagag cagcttgttg
    29041 ggcttcaaga gtcaagttgt aaatatcttt cttgaattgg tctggtttgc cgacagcgac
    29101 tgtacgagtc atatctgacg catagccatt gaccagaaca cccaggtcaa agaggagaag
    29161 agcatcattt tcaaccttat tagctgctgg aatgccgtgt ggattcgcag cattatcacc
    29221 agtcaagacc atggtatcaa agctcatttc gtaaccttca cgtttcatgg caaagtcaat
    29281 ttgtgcgatg atatctgtct cagtcttatc aagagaaata ttgtcaaaac caacatgaac
    29341 agccttgtca gcataaagac ctgcaaccat cattttttgc acttcatcag ctgatttgat
    29401 gaggcgcatg cgttggatac gaggagtgag gttgtcaaac tcagcagtct caaaaactgt
    29461 tttcaaacca tggtatttgg tcaagatgag attgtcaaac tcaacagcga cacgtttgaa
    29521 gtcaagttgt ggaagagcat gtttgatttt ttgccatgga ttttcagaat cgacatagcc
    29581 cactactggg aaggaaacgg tgctacttgc acgttctact tcaagagctg ggacaaagag
    29641 gagaggttcc tgatctgcta ggacaaagag gaacatttgg cgttcatggg gatcactgta
    29701 aaaaccagtg aggtaattga ttgtgacggg gtcagatacg acagcgacgt ctagtttttc
    29761 tgattcaaga tatgttagga tttgttgtaa tttagacata tgctaccttc tttctatccc
    29821 tctattttgg caaaaaatga gagaaaatgc aagggagaag ggtaaaagaa aagacaaaaa
    29881 actccgacaa gataacggag ttctttgata tcattttcct ttgtttaaga aaagtcagcc
    29941 ttgcttttga cgtcactgta ctcttcagcg atttcttggc tgaggatatc ctcataggca
    30001 gggagttgga tgtcctgacc atatttcttc ttgagggcag tagtaactag gcgataagcc
    30061 agattggcat tacgagagag gataggcccg tggaagtagg aaccaaagac attcttataa
    30121 tgaacccctt caccgacctt ttcttcgttg tttccatttc catagacaac ctgtcccagc
    30181 ggtttttggt catcagagag gaaggtacgg ccttggtgat tttcaaatcc atagtaggtt
    30241 tcatcgaaat cttcattgtg aatcttgatg tcaccgataa aacggttatt ggtctggttg
    30301 agcgtgtagt gtcccatgac ccctagccct tcgatacgtt ttcctgaagc ttcaacataa
    30361 tattgaccca atagttggaa accaccgcag atagccagaa ctacaccgtc gttttggatg
    30421 tagttgtcaa tgctctcttt tttagcaggt aggtcgtctg caatgatact ttgttcaaag
    30481 tcttgaccac caccgaaaaa ggcgatgtcg tagtgatttt catcaaagtc atcatggaga
    30541 gaaacgatgt caacggtcac atgggctccc agtttttcag ccacatactt gagcatgagg
    30601 atgtttccat tgtccccgta ggtattcatg agatttccgt agaggtgggc aatgttgagc
    30661 tgataggggt aattgccatc ttttgaggaa agtgaagtat aaaccattag ttcatctcct
    30721 ttctaacaat ctgacgacta gccagcagtt cacgaaattc cagcatggca gtataagttg
    30781 ccagaatata ggcatgcttg cagtcttgat tctcaatggt cttgagaact tgctccagat
    30841 tactcgtttc agtgattttc tcagctggat agccagtcac tcggaggcga cgagcgattt
    30901 cagaatgacg aacaccgcca gcgttgattt caggaatgtc catgtcagtg atttgttcaa
    30961 agtctgcatc ccagatccag ctagtgtcaa ttccatctgc atagttggca ttaaggagga
    31021 cagataggct aaatggataa ggtgctagtt tgatcatttc gatagcttgg gttgcaccga
    31081 ctggattttt aatcaagaca agggtacatt ccttgtcacc gatatgaaag gtttcttggc
    31141 gtccaaagac agcacggctc ttgtcaaatc cctgtttgat gagttgcgaa tcggcaccta
    31201 ggaaacgggc gatggccaca gcagctaggg cgttatagat attatagagc ccgccgattt
    31261 ggataccgta ttcttggacg tctatgacaa agcgagagcg attgttggtc aactcaacca
    31321 gttttgtcaa acgatagtcg agatcaggac gtttacatcc acaaccttca cagatatagg
    31381 tacccaagtt tgcataggta ttatgctcat atttgaggat gccttggcag tcaggacaga
    31441 gaatcccttc ggtattgtag tgagccagtt gggctggtcc tttttccaag tcaaaaccaa
    31501 aatactctat agggtttgga atagttggct tgtagaaaag tggactgtct ccgttaagga
    31561 gaacagtagc agttggaact ttccgaatgg catccaatat catgttatag gtagtataga
    31621 tttcaccgaa acggtccatc tggtcacgga agatattagt aatgacaaaa agactaggct
    31681 ggatatagtc acagatacga gatagactgg cttcgtcaat ttcgaggacg gcaatatttt
    31741 ttccagtttt agaagatttg gctgttagga aggttgttgc aatccctgta atcatgttgg
    31801 caccgcttgg attggttaga acttgaccat agacctcttt taaaatgccg acagtgaggg
    31861 cagttgtcag ggtttttcca tttgttccag tgacaacgac aatctcgtag ttcttagcta
    31921 ggttttgtaa aatatcttta tcaaattgaa gggcgacttt acctgggagc gtacttccac
    31981 ggccaagacg gcttaaaatg aagtgggaag aacgcccagc aagaaggccc aaagtagttt
    32041 ttaagttcat gtttctatta tatcataaaa gaggagaaag acagatttga gattccgcag
    32101 aagtaaaaac agcccaaaga gggctgttcg atacgattaa atctcaactt aaatcgcaaa
    32161 caagtcattc aagttctcag ccaaggttgg gtgagtgaag atttgttttg tgaagtaagt
    32221 gtaaggaatc ttgttgtcca tagcaacagt gatgatgttg atgatttctt gagaaccttc
    32281 tgagaagatg cttgctccaa gaatttcttt tgtttcagta ttgacaacag ctttgaaggc
    32341 accgcgaagg tctccattta cgtgaccacg aggcatggct gcaacgggga tttccttaac
    32401 agcgtatgga agtttcaaat cagctgcttg gctttcagtc aaaccaactt gtgaaagtgc
    32461 aggtgtgatg aacatagtat ttggcacatt gagacggtct tcaagtgtgt agctgccatc
    32521 tccagcaagg tagctgtaaa caacacggaa gtcatcaagt gaaatgtaag taaattgaag
    32581 gccaccgttg atatctccaa ctgcaaagac accaggaacg tttgtttgac agtgtttgtc
    32641 tactttaata gcaccacgtt cagttagttc aatatctgta ttttcaagtt gaagtggttc
    32701 tacatttggt ttgcgtccag ttgcgtagag aagggcgtcg aaacggtaag tttcgtcttc
    32761 agttacgaca agcacttggt caccatcgtt tttgatttca gtagtatgga tattttgaag
    32821 caattcaatg ccatcttctt ccatgtattg tttagcaaga gctgcgatgg aaggttctgc
    32881 acgaggaagg aaagtatcca aggcatctag gactgtgacc ttgcttccaa gtttgttgta
    32941 aaggccggca aattcaagac cgatatttcc gccaccaagg attccaagtt tttcaggtaa
    33001 tttgtccaag ttttggatac ctgttgagtc aaagatgttt ttgcttgtag caagtccagg
    33061 gattggcaag acgtttgaaa cagcaccagt gttgatgacg attgtttcag cagtcagttc
    33121 tttcttttca tcaccagctt ggatttcgat gactttattt gaaaggaagt gagcttccgc
    33181 atcaaagata tctacgcctg taccagcaac agtcgcatag tttttaccgt tgaggcgacc
    33241 agtgatcgtg tttttagtag caatcacttc ttcaaaagac aagtcctttt cagcagcaac
    33301 tagcaaggtt ttagttggga tacaaccaat gttgatacaa gttccaccgt acatagcctt
    33361 gctgcgttca acgagggcaa cttttttgcc agctgaagcc aatttacctg ctagtgtttt
    33421 accagcttta ccaaatccaa taacaattaa atcgtatgtt aacatttatc ttcctcctat
    33481 tcgaatttca ttctagcaca agaaaaaaac ttttgcacaa ttctgctacg gaaaagacag
    33541 aaaaagataa aaacgctttc cagacaaaaa actagtaatt ttttgacaag cttgataaac
    33601 taaaatccta tctattttta tataagatag aataaatgtt cgaaaatagg aggttttatg
    33661 aaatcgaatc gttatattat tgcctttgct ggggtcattt tacacttaat gctgggttcg
    33721 acttatgctt ggagtgttta tcgtaaccct attattgaaa aaacgggatg ggatcaggct
    33781 tctgttgcct ttgcctttag tctagcaatc ttttgtttgg gcttatcggc tgcatttatg
    33841 gggcgtttgg tagaaaaatt tggtccgaga gtcatgggga gtctatctgc ttttctatac
    33901 gcaggtggaa atatcttaac aggatttgca atagaccgtc aggagctgtg gttgttgtat
    33961 ctcgcttatg gcattttagg tgggcttggt ttgggagcag gctatattac ccctgtgtcg
    34021 acgattataa aatggtttcc tgataaacgt ggtctcgcaa caggtttagc gattatgggg
    34081 tttggttttg cttctttatt gactagtccc atagcgcaac acctcatcgc aggggtaggg
    34141 cttgtagaaa ctttttatat tttaggagca agttacttta ttatcatgct cctagcttca
    34201 caattcatta agcgtccaaa tgagcaagag cttgcaattt tatcttcttc agggaaagaa
    34261 aaaacagcct ctttgacgca aggaatggct gcaaatcagg ctctaaaaag caatcggttt
    34321 tatatacttt ggattatttt ctttatcaac atagcttgtg gtttaggctt aatttcagcg
    34381 gcatcgccaa tggcacagga gatggctggc ttgtctacaa gtcatgcagc agtaatggtg
    34441 ggcgttttag ggattttcaa tggatttggt cgcttgctct gggcgagctt atctgactat
    34501 atcggtcgcc ctctaacctt tagtatatta ctgcttgtta atcttttctt ttctctctca
    34561 ctttggctct ttacagattc cgttttattt gtagtcgcta tgtctatttt gatgacttgc
    34621 tatggagctg gtttttcatt gatcccagct tatctcagtg atatttttgg aaccaaggaa
    34681 ttggccgctc tgcatggata tattttaaca gcttgggcaa tggctggttt agcgggacct
    34741 attttattag cagagactta taaaatggct cattcgtaca cacaaacctt gttcgttttt
    34801 ctcattttat acagtatcgc cttggctttg tcttattatc taggtcgttc aatcaaaaaa
    34861 gaaagtcaaa aaccgcttac atgattttct gtagaaatgg ggctatcttt tgctctggtc
    34921 ttgtgttata ctagataggt tgcaaagaaa acagtacttt tcttttgtgg aaaagaagca
    34981 acacgatttt atatctagtt atatgaaaat acgtcataaa aagaaaagta taaactaagc
    35041 cctatagggt ggcttcgcac cacctttaga aagaagaata acgtgaaatt taatgaatta
    35101 aacttgtctg ctgatttgct ggcagaaatt gaaaaagctg gttttgtaga agctagtcct
    35161 atccaagaac aaactattcc tttggccctt gaaggcaagg atgttatcgg tcaagctcag
    35221 actggtacag gaaaaactgc agcctttggc ttgcctaccc ttgaaaaaat ccgtacagaa
    35281 gaagcgacta tccaagcctt ggtcatcgct ccaactcgtg aactagctgt ccaaagtcaa
    35341 gaagaactct tccgctttgg tcgtagtaag ggagtcaaag tccgttcagt atatggcgga
    35401 tcaagcattg aaaaacaaat taaggctctt aaatctggtg cccatatcgt ggtgggaact
    35461 ccaggtcgcc tcttggactt gattaaacgc aaggccttga aattacaaaa cattgaaacc
    35521 cttatccttg acgaagcgga tgaaatgctt aacatgggct tccttgaaga catcgaagcc
    35581 attatttccc gtgtacctga gaaccgtcaa actttgcttt tctcagcaac tatgccagat
    35641 gccatcaaac gtatcggtgt tcagtttatg aaagcccctg aacatgtcaa gattgcagct
    35701 aaggaattga caacagaatt ggttgaccag tactatatcc gtgttaagga acaagaaaaa
    35761 tttgacacca tgactcgtct catggatgtg gcacaaccag aactcgctat tgtatttggt
    35821 cgtaccaaac gccgtgtgga tgaattgact cgtggtttga aaattcgtgg cttccgtgca
    35881 gaaggaattc atggcgacct agaccaaaac aaacgtcttc gtgtccttcg tgactttaaa
    35941 aatggcaatc ttgatgtttt ggttgcgaca gacgttgcag cgcgtggttt ggatatttca
    36001 ggtgtgaccc atgtctacaa ctacgatatt ccacaagatc ctgagagtta tgttcaccgt
    36061 atcggtcgta caggtcgtgc tggtaagtca ggtcaatcta ttacttttgt tgctccaaac
    36121 gaaatgggtt accttcaaat cattgaaaac ttgactaaga aacgcatgaa aggtctcaaa
    36181 cctgcaagtg tagaagaatc cttccaatca aaaaaacagg tagctctcaa gaaaatcgaa
    36241 cgtgattttg cagatgaaac cattcgtgcc aactttgaga aatttggtaa ggatgctcgc
    36301 aaattggctg ctgagtttac tccagaagaa ttggcaatgt atatcttgag tctgacagtc
    36361 caagacccag atagccttcc agaagtggag attgcacgtg aaaaaccact accgtttaaa
    36421 ccatcaggta atggtttcgg tggtaaagct aagggaggtc gtggaggccg tcgtggggac
    36481 gaccgtcgag agcgtgatcg ccgtggcaat ggtcgccgtg atgagttcaa aaaaggaagt
    36541 cgtggcaacg atcgttttga taaggaaaaa cgttaccgta aggataataa aaaaccacgc
    36601 aatactttaa gcgaaaagca aacaggcttt gttattcgta acaaaggcga taaataagaa
    36661 aaagcggttc aaaatgaatc gcttttttat ataaggagac cgaatgtgaa aagacaaata
    36721 aaattattat attatctttt ataatgttat gatacacaaa aataggcaac ttgtcaatag
    36781 aaaaggaaca atttaattaa aaatattctg gtttttaatt aaattgtaag tcaatgcaag
    36841 tcaataagga attttcagat aattattgaa aaagagacgt ttttatgtta taatgatagc
    36901 gattaaattc gaggtgaaaa atggcacatt tattagaaaa aactagaaaa attacatcaa
    36961 ttttgaaacg ctcagaggag cagttgcagg atgagctccc ttacaacgct attacgcgtc
    37021 agttagcgga tattattcat tgcaatgcct gcattatcaa tagtaaggga cgtctgcttg
    37081 gctattttat gcgttataaa acaaatacag atcgcgtaga gcaattcttc caaactaaga
    37141 ttttcccaga tgactacgtt caaggggcta atatgattta cgaaacagaa gcaaacttgc
    37201 ctgttgagca tgatatgagt attttccctg ttgagagtag agatgatttt ccagatggct
    37261 tgacgactat tgcaccgatt catgtatcgg ggattcgcct tggttctttg attatttggc
    37321 gtaatgataa aaaattcgaa gatgaggact tggttcttgt tgagattgcc agtaccgttg
    37381 ttgggattca gcttcttaac ttccaacgtg aagaagatga gaaaaatatt cgtcgtcgta
    37441 ctgctgtcac catggcggtc aatacccttt cttactccga actccgtgct gtttcagcaa
    37501 ttttagggga attaaatgga aatgaagggc agttgactgc gtcagtgatt gcagatcgta
    37561 tcggaatcac tcgctctgtg attgtcaatg ctcttcgtaa acttgagtct gcggggatta
    37621 ttgaaagtcg ctcacttgga atgaagggaa cctatcttaa ggtcttgatt tcagatattt
    37681 ttgaagaagt gaagaaaaga gattactaat gacaaaggct ttaatttcga ttgattatac
    37741 agaagatttt gttgctgata gtgggaagct gacagcaggt gctccagctc aggcgatttc
    37801 ggatgccatt agcaaggtaa ctcgattagc ttttgaacga ggagattata tcttctttac
    37861 tattgatgct catgaagaaa acgatttttt ccatccggaa agtaagttat ttcctcctca
    37921 taatctgatt gggacgagtg gacggaattt atatggagat ttggggatct tttatcaaga
    37981 gcatggttca gacagtcgtg tcttttggat ggataaacgc cattactcag ctttttcagg
    38041 gactgaccta gatattcgtt tgagagagcg tagagtgtct accgttatct taacaggtgt
    38101 cttgacggat atctgtgtcc tacatacagc tatagatgcc tataatctag gatatgacat
    38161 cgagattgtt aaaccagctg ttgcttccat ctggcctgaa aatcatcaat ttgccctagg
    38221 tcatttcaaa aatacactcg gagctaagtt agtagatgaa aatctaaatg aactttctga
    38281 gtaacctggt tggtgaaaat gaaaaaattt gaaaaaaagt gttgacaagc atcccaaaag
    38341 ttgatatact agtaaagtaa tcgatgcggg gatggcggaa ttggcagacg cgcaggacta
    38401 aggatcctgt gaccgcttta ggtcgtgagg gttcaagtcc ctctctccgc ataggaaaag
    38461 agttagctaa agctagctct tttgtatttc tctaaaaaat tagaatccag tcaaatgtag
    38521 tggagaatca gcgaaaatat gggaaaactg atccttgttt ctgcttttgt catagaagaa
    38581 taataaagat tatcttcttc aaattctccg atattctcta aagttttgtg caagttgcac
    38641 agaacttttt tatttttttg gtcatcttgc catagaaata taaagcgttt tcatatataa
    38701 tataattatc aaaagacaaa aggagttcac ctcatggtag aattgaatct taaaaatatt
    38761 tacaaaaaat atccaaacag cgaacactat tcagttgaag atttcaactt gaacataaaa
    38821 gataaagaat ttatcgtttt cgtaggacct tcaggatgtg gtaaatcaac tacactccgt
    38881 atgattgctg gtcttgaaga cattacagaa ggtactgcat ctatcgatgg cgtggttgtc
    38941 aacgacgtag ctccaaaaga ccgtgatatc gccatggtat tccaaaacta cgctctttac
    39001 ccacacatga ctgtttatga caacatggct ttcggcttga aattgcgtaa atacagcaaa
    39061 gaagacatta acaaacgtgt tcaagaagca gctgaaatac ttggattgaa agaattcttg
    39121 gaacgtaaac cagctgacct ttcaggtggt caacgtcaac gtgttgccat ggggcgtgcg
    39181 attgtccgtg atgcgaaagt attcttgatg gacgaacctt tgtcaaactt ggatgccaaa
    39241 cttcgtgtat caatgcgtgc tgaaatcgct aaaattcacc gtcgtatcgg agctacaact
    39301 atctatgtaa ctcacgacca aacagaagcg atgacacttg cagaccgtat cgttattatg
    39361 tcagctacta agaaccctgc tggtacaggt actatcggac gtgtagaaca aatcggtact
    39421 cctcaagaag tttacaaaaa tccagttaac aaattcgttg caggattcat cggaagccca
    39481 gctatgaact tcatcaccgt gaaattggtt ggtagcgaaa ttgtttctga cggtttccgt
    39541 ttgaaagtgc cagaaggagc attgaaagtt cttcgtgaaa aaggctacga aggaaaagaa
    39601 ttgatctttg gtatccgtcc agaagacgtg aatgcagaac ctgctttcct tgaaacattc
    39661 ccagactgtg ttgtaaaagc gactatctct gtatcagaac tgcttggttc agaatctcac
    39721 ctttactgcc aagttggtaa agacgagttt gttgcaaaag ttgatgctcg tgactacttg
    39781 caaacaggtg caacagttga gcttggattt gacttgaaca aagcacactt cttcgatgta
    39841 gaaactgaaa aaacaatcta ctaaaataaa taaaattcaa agcactacaa gaaaagatat
    39901 ctctttatca attgtagtgg agagatatca gttaatctag ggagagaaac aaaatgcttc
    39961 tctccttttt gctagggaag tcatattatg catctatatt gtgatgctct ttatactctt
    40021 cgaaaatctc ttcaaaccac gtcaacgtcg ccttgccgta cgtatgatta ctgatttcgt
    40081 cagttttatc tgcaacctca aagatgtact ttgagcagct tacggctagt ttcctagttt
    40141 gctctttgat ttccattgag tattattgtg agtaccatct acaagtgaag ctatatgcgt
    40201 aaactacgtg agcaattgaa ttcgaactag agaggtaata ataaatttat gctatagtta
    40261 tggtgacttg tatgcttttg attctagttt atcaaataat agattagaat tgtcagataa
    40321 tatcattttg tgttataatg aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat
    40381 aagtttttag caaaattggg gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat
    40441 tggttaattg cagaaggagg attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat
    40501 aggggaacta cagcaattga gttggcacag cgttttggtt gcaagataac tgctgttgat
    40561 atggatgctc aagctttaga agtggctaaa aaatctgctg gaacggcagg tgttgctcat
    40621 ttaatcagtt ttgaaagagc aaatgcaatg aaacttcctt atcaagatgc tagttttgat
    40681 attgttataa atgaagctat gctgactatg caagccgatc aagctaagaa aaaatgtgta
    40741 atggaatatc taagggtatt aaaacctgga ggtcttctct tgacacatga tgtgcttctt
    40801 aaggaagcta aagagtctat cagacaggaa ttatcacaag caattcatgt aaatgtaggt
    40861 cctttaactc aagatggttg ggaacaggtg atgatagaat caggttattg tgatgtgaaa
    40921 gcattgactg gtgaaatgac attaatgaaa ttatcgggta tgatttatga cgaaggtttg
    40981 ctaggaactt tgaaaatttg tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta
    41041 actatgtata aaatgtttgc taagaataaa cagaaattgg gctttattgc gatggctagt
    41101 tataaatcgt caaaacgtta gataattatt gaagttaact tttccttttt tctttcttaa
    41161 aaaatatgct ataatagaga gtaaaaaact ttgaaagaaa gaaaaaagat gaatttaaaa
    41221 gattacattg caacaattga aaattatcca aaggaaggca ttaccttccg tgatattagt
    41281 cctttgatgg ctgatggaaa tgcttatagc tacgctgttc gtgaaatcgt tcagtatgct
    41341 actgacaaga aagtcgacat gatcgtggga cctgaagctc gtggatttat cgtgggttgt
    41401 ccagttgcct ttgagttggg aattggtttt gcgcctgttc gtaagccagg taaattgcca
    41461 cgtgaagtta tttctgctga ctatgaaaaa gagtacggtg tcgatacctt gactatgcac
    41521 gcggatgcca ttaagccagg tcaacgtgtt cttattgtag atgacctttt ggcgacaggt
    41581 ggaactgtta aggcaactat cgagatgatt gaaaaacttg gtggtgttat ggcaggttgt
    41641 gccttccttg ttgaattgga tgaattgaac ggccgtgaaa aaattggtga ctacgactac
    41701 aaagttctta tgcattatta atgaaaacag tccctagggc tgttttctct acactaggat
    41761 ataaaaatag actataacta gttagagaaa aactataatt gaaaactata tcttcttgca
    41821 gtataataaa aggactaagt gtttgagatt tgtcttcaaa catatgcaat tattcctgaa
    41881 agagtacagt taggagaggg ttatgccgat tcgaattgat aaaaaattgc cagctgttga
    41941 gattttacgg acagagaata tctttgtcat ggatgatcaa cgtgctgccc accaagatat
    42001 ccgtcctttg aagattttaa ttttaaatct catgccacag aaaatggtca cagagaccca
    42061 gttgttgcgc cacttggcta atacacccct acaactggat attgattttc tctatatgga
    42121 gagccaccgt tctaaaacaa ctcgttcaga gcacatggag accttctata aaacttttcc
    42181 tgaagtcaag gatgagtatt ttgatgggat gatcatcacg ggtgctccag ttgagcattt
    42241 accatttgag gaagtggact attgggagga atttagacag atgcttgagt ggtctaagac
    42301 tcatgtctat tcgacccttc atatctgttg gggggctcag gctgggcttt atctgcgcta
    42361 tggtgtagaa aaataccaga tggacagtaa gctatcaggt atttatcctc aggacaccct
    42421 aaaagagggt caccttctat ttagaggctt tgatgatagc tatgtatccc ctcattcacg
    42481 gcacacggag atttctaagg aagaggtctt aaacaagacc aatctcgaga ttttatcaga
    42541 aggacctcag gttggggttt ctattttggc cagtcgtgat ttacgagaaa tttatagttt
    42601 tggtcatttg gagtatgacc gtgatacctt ggcaaaagag tattttcgag atcgtgatgc
    42661 aggtttcgac ccacatattc cagaaaatta ctttaaagat gatgatgtta atcaggtacc
    42721 ttgtctttgt tggtcttcat ctgcagccct ctttttcagt aattgggtaa accatgcggt
    42781 ctatcaggag acgccttttg attggagaaa gatagaagat gatgcatctg catatgggta
    42841 tttataagag gaattatgac atatttagac gcttttaaat caggtacctt ggttttaccg
    42901 agtgccctgc tcttgcattt taaggaactc tttccttcta gcgacgattt tctggtttgg
    42961 caatttttct atttgcaaaa tacgacaggc ttagaagaaa tgtcgccaag ccagattgct
    43021 gaaaggattg gcaaggaaat ttcggatgtc aaccagtcca tttctaatct gacggaaagg
    43081 ggactgctcc agtatcgtac tatcgaatta aatggcgaaa ttgaattgct ctttgatgct
    43141 agtttggcct tggaacgttt ggatgacctg tttggagcag ttcattcaag ttcagaccag
    43201 ctaacacctc aaaaccagct caaggatttg gtggaaacct tccagcagga gttgggacga
    43261 ttgttgacgc cttttgagat tgaggatttg accaagacac taaaggaaga tggaaccagt
    43321 gctgacttga ttaaggaggc tcttcgtgaa gctgttttga atggaaaacc aaactggaag
    43381 tacattcagg ctattttgag aaactggcgc catgaaggaa tcaagagtgt ggctcaaatt
    43441 gaggccaaga gagcagaaag agaagcaagc aatcctcagt tgacacaggt atctgcagat
    43501 ttcagaaatg ccatggatct ctggaaggat taatccatgc aagtaggctt gaaatccgag
    43561 taagatttgc aagctgtgta taattgtgat agaataaata gaaaataaat tgaaaaaaga
    43621 ggtatgtgaa atgtcacgta aaccatttat cgctggtaac tggaaaatga acaaaaatcc
    43681 agaagaagct aaagcattcg ttgaagcagt tgcatcaaaa cttccttcat cagatcttgt
    43741 tgaagcaggt atcgctgctc cagctcttga tttgacaact gttcttgctg ttgcaaaagg
    43801 ctcaaacctt aaagttgctg ctcaaaactg ctactttgaa aatgcaggtg ctttcactgg
    43861 tgaaactagc ccacaagttt tgaaagaaat cggtactgac tacgttgtta tcggtcactc
    43921 agaacgccgt gactacttcc atgaaactga cgaagatatc aacaaaaaag caaaagcaat
    43981 ctttgcgaac ggtatgcttc caatcatctg ttgtggtgaa tcacttgaaa cttacgaagc
    44041 tggtaaagct gctgaattcg taggtgctca agtatctgct gcattggctg gattgactgc
    44101 tgaacaagtt gctgcctcag ttatcgctta tgagccaatc tgggctatcg gtactggtaa
    44161 atcagcttca caagacgatg cacaaaaaat gtgtaaagtt gttcgtgacg ttgtagctgc
    44221 tgactttggt caagaagtcg cagacaaagt tcgtgttcaa tacggtggtt ctgttaaacc
    44281 tgaaaatgtt gcttcataca tggcttgccc agacgttgac ggtgcccttg taggtggtgc
    44341 gtcacttgaa gctgaaagct tcttggcttt gcttgacttt gtaaaataat cagtaagtag
    44401 caaaagctag gtggaacagc attcagatgt ctgttacatt ttttatagga gagcaaagat
    44461 tgaaaacaaa aattggatta gcaagtatct gtttactagg cttggcaact agtcatgtcg
    44521 ctgcaaatga aactgaagta gcaaaaactt cgcaggatac aacgacagct tcaagtagtt
    44581 cagagcaaaa tcagtcttct aataaaacgc aaacgagcgc agaagtacag actaatgctg
    44641 ctgcccactg ggatggggat tattatgtaa aggatgatgg ttctaaagct caaagtgaat
    44701 ggatttttga caactactat aaggcttggt tttatattaa ttcagatggt cgttactcgc
    44761 agaatgaatg gcatggaaat tactacctga aatcaggtgg atatatggcc caaaacgagt
    44821 ggatctatga cagtaattac aagagttggt tttatctcaa gtcagatggg gcttatgctc
    44881 atcaagaatg gcaattgatt ggaaataagt ggtactactt caagaagtgg ggttacatgg
    44941 ctaaaagcca atggcaagga agttatttct tgaatggtca aggagctatg atgcaaaatg
    45001 aatggctcta tgatccagcc tattctgctt atttttatct aaaatccgat ggaacttatg
    45061 ctaaccaaga gtggcaaaaa gtgggcggca aatggtacta tttcaagaag tggggctata
    45121 tggctcggaa tgagtggcaa ggcaactact atttgactgg aagtggtgct atggcgactg
    45181 acgaagtgat tatggatggt gctcgctata tctttgcggc ctctggtgag ctcaaagaaa
    45241 agaaagattt gaatgtcggc tgggttcaca gaaacggtaa acgctatttc tttaataata
    45301 gagaagaaca agtgggaacc gaacatgcta agaaaatcat tgatattagt gagcacaatg
    45361 gtcgtatcaa tgattggaaa aaggttattg atgagaacga ggtggatggt gtcattgttc
    45421 gtctaggtta tagcggtaaa gaagacaagg aattggcgca taacattaag gagttaaacc
    45481 gtctgggaat tccttatggt gtctatctct atacctatgc tgaaaatgag accgatgctg
    45541 agaatgacgc taaacagacc attgaactta taaagaaata caatatgaac ctgtcttacc
    45601 ctatctatta tgatgttgag aactgggaat atgtaaataa gagcaagaga gctccaagtg
    45661 atacagacac ttgggttaaa atcatcaaca agtacatgga cacgatgaag caggcgggtt
    45721 atcaaaatgt gtatgtctat agctatcgta gtttattaca gacgcgttta aaacacccag
    45781 atattttaaa acatgtaaac tgggtagcgg cctatacgaa tgctttagaa tgggaaaacc
    45841 cttattattc aggagaaaaa ggttggcaat atacctcttc tgaatacatg aaaggaatcc
    45901 aagggcgcgt agatgtcagc gtttggtatt aagcgatgat ttgaaagagg gatgtgatag
    45961 tagcaccctc tttttctttg ttttatgata gttcatcctc gagtaaattc aagatcttgc
    46021 tcggaaatga agcttatata gtagattgaa tatagacaaa taccttgtga ttggtaaaac
    46081 attttagaaa ttcatttacc tttcctaatc gacttggttt catcttattt caatctatta
    46141 tagtattggg gaatttcttc aaaccacatc agcttggtca gttctacctg cgacctcaaa
    46201 acttgtgctt tggtcaagct gggtttagtt tcctagtttg ctgatggatt tccattgact
    46261 ataagcatcc aaccctcttt ttgtcttcta aagaattctt aaattatcag tctattgcaa
    46321 cttttctcat ataagttctt tgtcttgcta tttgttttcc ttagtagtat actaaggtag
    46381 taatcattaa gaagtggtta caaaaaataa tgaatgaggt aaagaaaatg gtagaattga
    46441 aaaaagaagc agtaaaagac gtaacatcat tgacaaaagc agcgccagta gcattggcaa
    46501 aaacaaagga agtcttgaac caagctgttg ctgatttgta tgtagctcac gttgctttgc
    46561 accaagtgca ctggtatatg catggtcgtg gtttccttgt atggcatcca aaaatggatg
    46621 agtacatgga agctcttgac ggtcaattgg atgaaatcag cgaacgcttg attacactcg
    46681 gtggaagccc attctctaca ttgacagagt tccttcaaaa tagtgaaatc gaagaagaag
    46741 ctggtgaata ccgtaatgtt gaagaaagct tggaacgtgt tcttgttatc taccgttact
    46801 tgtcagaact tttccaaaaa ggtttggatg tcactgatga agaaggtgac gatgtgacaa
    46861 acggtatctt tgcaggcgct aaaactgaaa cagataaaac aatttggatg cttgcagccg
    46921 aacttggaca agcacctggt ttgtaagaaa taaggaaaca tagataaatc tgtaggaaat
    46981 ttcttacaga ttttttctat tttgtaagct attccaaacc agtctttttt tgagtttttt
    47041 gataaaatag tactatcagt gaaaaggatg gaagcatgac taagaaaatc gtagctattt
    47101 gggcccagga tgaagagggt gtgattggta aggaaaatcg tctgccttgg catttgccag
    47161 cagaattgca gcactttaaa gaaacaactc tgaatcatgc tatcttgatg gggcgtgtga
    47221 cctttgatgg gatggggcgt cgcttgcttc caaaacggga aaccctgatt ttgacgcgta
    47281 atccggaaga aaagatagat ggggttgcta cttttcagga cgtccagtct gttcttgact
    47341 ggtatcagga tcaagaaaag aatctctaca ttatcggtgg gaagcaaatt tttcaggctt
    47401 ttgaacctta ccttgatgaa gtgattgtca ctcacattca tgctcgggtg gaaggagata
    47461 cctatttccc tgaagagctt gacttgtctc tttttgagac agtttcaagc aaattttacg
    47521 ccaaagatga gaagaatcct tatgatttta ccatccaata ccgcaagaga aaggaagtat
    47581 aatggaacgg agtttatttg gtctattcac ggcttttctg tgtttcatct gctttctggc
    47641 aggagcacag gcttttcgta aaaagcgtta cgggctttct atcctccttt ggttaaatgc
    47701 ctttaccaat ctggtcaata gtattcatgc tttttacatg accttatttt agatagaatg
    47761 acagtataga atggaaggaa atcatgtcta caaatagaaa aaatgatatg atggtttatt
    47821 gctcattttg tggcaaaaac caagaagaag tacaaaaaat aattgctggc aacaatgctt
    47881 ttatttgtaa tgaatgcgtg gagttagctc aggaaatcat tcgagaagaa ttggttgagg
    47941 aagtcttggc agacttgtct gaggtgccaa aaccaattga actcctccat atcttgaacc
    48001 actatgtaat tggtcaagat cgtgccaagc gtgccttggc agtggcggtt tataaccact
    48061 acaaacgcat caatttccac gatacacgcg aagagtcaga agatgtggat ttgcagaagt
    48121 caaacatttt gatgattggc ccaactggtt cagggaaaac tttccttgcc cagaccttgg
    48181 ctaagagctt gaatgtgcct tttgctattg cggatgcgac agctctgacg gaggctggtt
    48241 atgtgggtga ggacgtggaa aatatcctcc tcaaactctt gcaggttgct gactttaaca
    48301 tcgaacgtgc agagcgtggc attatctatg tggatgaaat tgacaagatt gccaagaaga
    48361 gtgagaatgt gtctatcaca cgtgatgttt ctggtgaagg ggtgcaacaa gcccttctca
    48421 agattatcga gggaactgtt gctagcgtgc cgcctcaagg tggacgcaaa catccacaac
    48481 aagagatgat tcaagtggat acaaaaaata tcctcttcat cgtgggtggt gcttttgatg
    48541 gtattgaaga aattgtcaaa caacgtctgg gtgaaaaagt catcggattt ggtcaaaata
    48601 ataaggcgat tgacgaaaac agctcatata tgcaagaaat catcgctgaa gacattcaaa
    48661 aatttggtat tatccctgag ttgattggac gcttgcctgt ttttgcggct cttgagcaat
    48721 tgaccgttga tgacttggtt cgcatcttga aagagccaag aaatgccttg gtgaaacaat
    48781 accaaacttt gctttcttat gatgatgttg agttggaatt tgacgacgaa gcccttcaag
    48841 agattgctaa taaagcaatc gaacggaaga caggggcgcg tggacttcgc tccattatcg
    48901 aagaaaccat gctagatgtt atgtttgagg tgccgagtca ggaaaatgtg aaattggttc
    48961 gcatcactaa agaaactgtc gatggaacgg ataaaccgat cctagaaaca gcctagaggt
    49021 gactatggaa cttaatacac acaatgctga aatcttgctc agtgcagcta ataagtccca
    49081 ctatccgcag gatgaactgc cagagattgc cctagcaggg cgttcaaatg ttggtaaatc
    49141 cagctttatc aacactatgt tgaaccgtaa gaatctcgcc cgtacatcag gaaaacctgg
    49201 taaaacccag ctcctgaact tttttaacat tgatgacaag atgcgctttg tggatgtgcc
    49261 tggttatggc tatgctcgtg tttctaaaaa ggaacgtgaa aagtgggggt gcatgattga
    49321 ggagtactta acgactcggg aaaatctccg tgcggttgtc agtctagttg accttcgtca
    49381 tgacccgtca gcagatgatg tgcagatgta cgaatttctc aagtattatg agattccagt
    49441 catcattgtg gcgaccaagg cggacaagat tcctcgtggt aaatggaaca agcatgaatc
    49501 agcaatcaaa aagaaattaa actttgaccc gagtgacgat ttcatcctct tttcatctgt
    49561 cagcaaggca gggatggatg aggcttggga tgcaatctta gaaaaattgt gaggaaaaga
    49621 aaatggcaaa aacaattcat acagataagg ccccaaaggc tatcggaccc tatgttcaag
    49681 gaaaaatcgt tggcaacctt ttgtttgcta gcggtcaagt tcccctatcc cctgaaactg
    49741 gggaaattgt aggagagaat atccaagaac agacagagca agtcttgaaa aacatcggtg
    49801 ctattttggc agaagcagga acagactttg accatgttgt caaaacaact tgtttcttga
    49861 gcgatatgaa cgactttgtt ccttttaatg aggtttacca aacggccttc aaagaggaat
    49921 tcccagctcg ttcagctgtg gaggtagctc gtcttcctcg tgatgtaaaa gtcgaaattg
    49981 aagtcatcgc agagattgga taagctagtt gaagtttggt gttgccaaac ttcttttgat
    50041 ataaggagaa aaagatgaca aagaaacaac ttcacttggt gattgtgaca gggatgagtg
    50101 gcgcagggaa aactgtagcc attcagtcct tcgaggatct aggttatttc accattgata
    50161 atatgccgcc agctctcttg cctaagtttt tgcagctggt tgaaattaag gaagacaatc
    50221 ctaagttggc cttggtagtg gatatgcgta gccgttcttt cttttcagag attcaagctg
    50281 ttttggatga gttggaaaat caagatggtt tggatttcaa aatcctcttt ttggatgcgg
    50341 ctgataagga attggtcgct cgttacaagg aaaccagacg gagtcaccca ctagcagcag
    50401 acggtcgtat tttagatgga atcaagttgg aacgtgaact cttggcacct ttgaaaaata
    50461 tgagccaaaa tgtggtggat acgactgaac tcactccacg tgagctgcgc aaaacccttg
    50521 cagagcagtt ttcagaccaa gaacaagccc agtctttccg tatcgaagtc atgtctttcg
    50581 gatttaagta tggaatcccg attgatgcgg acttggtctt tgatgtccgt ttcttgccaa
    50641 atccctatta tttaccagaa ctgagaaacc aaacgggtgt ggatgaacct gtttatgatt
    50701 atgtcatgaa ccatcctgag tcagaagact tttatcaaca tttattggcc ttgattgagc
    50761 cgattctgcc aagttaccaa aaggaaggta agtccgtttt gaccattgcc atgggatgta
    50821 cgggtggaca acaccgtagt gtggcatttg ctaaacgctt ggtgcaggac ttatccaaga
    50881 attggtctgt taatgaaggg catcgcgaca aagaccgcag aaaggaaacg gtaaaccgtt
    50941 catgagaaaa ccaaagataa cggtgattgg tggagggact ggaattcccg tcattctaaa
    51001 aagtctgcgg gaaaaagatg tggaaatcgc agctatcgtg acggtggcag atgatggtgg
    51061 ttcttcaggt gaactccgaa aaaatatgca acagttgaca ccgccaggtg attttcgtaa
    51121 tgtccttgtg gccatgtcgg atatgcctaa gttttatgag aaggtctttc agtatcggtt
    51181 ctctgaggat gccggagcct ttgctggcca tccattggga aatctcatca ttgctggctt
    51241 gtcagaaatg cagggttcaa cctataatgc catgcagtta ttgagcaaat ttttccatac
    51301 aacagggaaa atttatcctt ccagtgacca tcctttgacc cttcatgcag tctttcagga
    51361 tgggacagaa gtggctggag agagtcatat tgtagaccat cgaggcataa ttgacaatgt
    51421 ctatgtgacc aatgccctaa acgatgatac gcctctggcc agccgtcgag tagtgcagac
    51481 catccttgaa agtgacatga ttgtcctagg gccaggttct ctctttacct ctattttgcc
    51541 caatatcgtg attaaggaaa ttgggcgggc tcttttggaa accaaggcag aaattgccta
    51601 tgtctgcaat atcatgaccc aacgtgggga gacggaacac tttacagata gcgaccacgt
    51661 ggaagtcttg catcgtcacc ttggtcgccc ttttatcgac actgtcttgg tgaatattga
    51721 aaaagtgcct caggaataca tgaattccaa ccgttttgat gaatacttgg tgcaagtgga
    51781 acacgatttt gtaggtcttt gtaagcaagt ttcgcgcgtg atttcatcta acttccttcg
    51841 tctggaaaat ggcggtgcct tccacgatgg agatttgatt gtggacgagt tgatgcgcat
    51901 tatacaggtg aaaaaatgag tttcacagta gcagtaaaag aagaaatcct gggccaacac
    51961 catctgagct ggcatgaatt atctgccatt atcaaaatgt ctggtagcat cggtctctcg
    52021 acttcgggct tgactttgtc agttgtgaca gaaaatgcca aactggcccg tcacctctat
    52081 gagtcctttc tccatttcta tgaaatcaaa tctgaaattc gtcaccacca acggagcaat
    52141 cttcgcaaga atcgcgtcta taccgttttt acagatgaaa aggtgcagga tttgttaagt
    52201 gatttgcact tggcagactc tttctttggc ctggaaacag gtattgatga ggcgatttta
    52261 tcggatgagg aagcaggtcg tgcctatctc tgtggcgctt tcttggcaaa tgggagcatt
    52321 cgtgaccctg agtcaggcaa gtaccagttg gaaatcagtt ctgtttatct ggaccacgcg
    52381 caaggaattg cctcccttct ccaacagttt ttactggatg ccaaggtgct tgagcgcaag
    52441 aagggggctg tgacctatct ccagcgagca gaagacatta tggacttctt gatagtaatc
    52501 ggagccatgc aggcacgtga tgattttgag cgggttaaga ttttgcgaga aacccgtaac
    52561 gacctcaatc gggctaataa tgccgagaca gctaatatcg ctcggacagt ttctgccagc
    52621 atgaagacca ttaacaatat cagtaaaata aaagatatca tgggcttaga aaatttgcca
    52681 gtagatttgc aggaagtggc gcaactgagg attcagcacc cagactactc tatccaacag
    52741 ttggcagata gcctcagcac ccctctgacc aaaagtggtg ttaatcacag actcagaaaa
    52801 atcaataaga tagccgatga attataaaac cacgaatcct atgtgactcg tggttctttt
    52861 ttataaacta gtagagtgtt ttggttgtac tttttgttca gggtcaatgt agttgatagc
    52921 gttgttgaca gcagttggag cttctccgag gcctgtcgca atcagatcaa tttttccgtc
    52981 atagtagcag cagtcaccga tagcatagat acctgcttgg ctggattcct gtttgctgtt
    53041 gacgataatc ttgtgacggt tgaggtcgag cccccagttt ttaaggttac cgacagaaga
    53101 tttgaaacca tagttgacaa agaggtggtc taggtcaatg gtttcagttt catcagattt
    53161 gacttttgtg atttcaagtt tatcaagtgt ttttccattt ccaaggagtt ggctaggggc
    53221 gaatggtgtc ttgatggtta cagatgattc ttgcaaggct tgaacactgt gttccaaggc
    53281 acggaaatta tctctgcggt gaacaagggt agttggtgcg attttttcaa aagccaaagc
    53341 ccaatccaca gccgagtctc ccccaccaag aatcgtcact ttcttaccag cgtattgctg
    53401 aatgttagaa acgtggtagt ggatattttc atagccctca acactttcaa gttccagcgg
    53461 acgtggtttg aaggcaccgc cacccatagc gatgataact gttttagtca ggtgacttcc
    53521 tttagaagtt gtgatggcaa attcttcttc ttgtttgtca atctcaagaa ccgtttcatt
    53581 gagatgaata ggggtatcaa atccatttag ctgttcaatc aagcggttag tcaactcttc
    53641 tccagtcagg tttgggaagc ctggtacgtc taggatttcc ttttcagggt agagaatagc
    53701 aggttgtcca cctagctggg gaagagagtc gatgatttga accttggctt ggcgtaggtg
    53761 ggcataaaag gctgcaaaaa gcccgacagg accaccaccc acaatggtaa tatcatagag
    53821 ttgagacata gtttctcctt tgttttttct agtcagttta ttttatcata tttttgttca
    53881 atgtaaaatg gactaggata gggaaaaaaa tgccagaaaa tggtataata ggacgaaagt
    53941 gttttgatag ggaggatatc agggatgaat tttcaacaat tatccaatct gcaatattgg
    54001 accagtttgt ttgcaagtcc atggacgata gctatcaatc tgattgatat tttgattgtt
    54061 gcttatattt tataccattt tacaaaagct attgcaggaa ccaagattat gattttggta
    54121 cgtggagttt tggtgtttat tttagctcaa atccttgcaa atatgattgg tttgactacg
    54181 atttcttggt taatcaatca aattattact tatggggtta ttgcggcggt tgttatcttc
    54241 tctccagaga ttcggactgg tttggaacgt ttgggaagag cgacagattt cttttccaat
    54301 gcccctatta gtgctgagga acagatgatt cgtgcctttg ttaagtctgt tgaatacatg
    54361 agtcctcgta aaatcggggc cttggttgct attcagcgtg tacgtacctt gcaggagtat
    54421 atgtcgacag gaattccctt ggatgctaag atttctgcag aacttctcat taacattttt
    54481 attcccaaca ctcccctaca tgacggtgcg gtgattatca aagaagaacg tatcgctgtg
    54541 acgtctgcct atctgccctt gacaaaaaac acagggattt ccaaggaatt tgggaccaga
    54601 caccgggcgg ctatcggttt atcagaagtc tcagatgcct tgacttttgt cgtatcagag
    54661 gaaacgggag gaatttcgat aacctataat ggaaggttta agcacaacct aacacttgat
    54721 gaatttgaaa cagaattacg tgaaatctta cttccaaaag aggaagtggg tcttagtttt
    54781 aaagaacgat tgctaggagg atggaaacat gaaaaaaaat agtttatata tcatatcctc
    54841 actctttttt gcttgtgtct tatttgtcta tgctacggcg acgaattttc aaaacagtac
    54901 cagtgctagg caggtaaaaa cggaaaccta tactaataca gtaacaaatg tccctattga
    54961 catacgctat aatagtgata agtattttat tagcggtttt gcttcagaag tatcagtggt
    55021 cttgactggt gcaaatcgcc tatcgctagc tagtgaaatg caagaaagta cacgtaaatt
    55081 caaggttact gctgacctaa cagatgccgg tgttggaacg attgaagttc ctttgagcat
    55141 tgaagattta cccaatgggc tgaccgctgt ggcgactccg caaaaaatta cagtcaagat
    55201 tggtaagaag gctcaaaagg ataaggtaaa gattgtacca gagattgacc ctagtcaaat
    55261 tgatagtcgg gtacaaattg aaaatgtcat ggtgtcagat aaagaagtgt cgattacgag
    55321 tgaccaagag acattggata gaattgataa gattatcgct gttttgccaa ctagcgaacg
    55381 tataacaggt aattacagtg gttcagtacc tttgcaggca atcgaccgca atggtgttgt
    55441 cttaccggca gttatcactc cgtttgatac aataatgaag gtgactacaa aaccagtagc
    55501 accaagttca agcacatcaa attcaagtac aagcagttca tcggagacat cttcgtcaac
    55561 gaaagcaact agttcaaaaa cgaattaaaa atagaaaagg attttataac aatgggtaaa
    55621 tattttggga ctgatggagt ccgtggagaa gctaacctag aactaacacc agaattagcc
    55681 tttaaactag gacgttttgg aggctatgtt cttagtcaac atgaaacgga agcgccgaaa
    55741 gtctttgtag gacgtgacac acgtatttca ggggaaatgc tggaatcggc cttggtggca
    55801 ggtctccttt cagtagggat tcacgtatac aaacttggtg tccttgcaac accagcagta
    55861 gcttacttgg ttgaaactga aggagcaagt gccggtgtca tgatttctgc tagccacaac
    55921 ccagcccttg ataacggaat caagttcttt ggcggtgatg gcttcaaact agatgatgaa
    55981 aaagaagcag aaattgaagc cttgctagat gctgaggaag acactcttcc tcgtccaagt
    56041 gcagaaggct taggaatttt ggtagattat ccagaaggct tgcgtaagta tgaaggatac
    56101 cttgtttcaa ctggaactcc tcttgatgga atgaaggttg ccttggatac agctaatgga
    56161 gcagcttcta ccagtgcccg tcaaatcttt gcagaccttg gtgcccaatt gacggttatc
    56221 ggggaaacac cagacggtct taacatcaac cttaatgttg gttcaacaca tccagaagcc
    56281 cttcaagaag tggtcaaaga aagtgggtca gctattggtt tggcctttga tggagacagt
    56341 gaccgcttga ttgctgttga tgagaatggt aacatcgtcg atggtgacaa gattatgtac
    56401 atcatcggaa aatacctttc tgaaaaagga caattggctc aaaatacaat tgtgacaact
    56461 gttatgtcta accttggttt ccacaaggcc ttgaatcgcg aaggtattaa caaggcagtt
    56521 actgcagttg gtgaccgcta cgttgttgaa gaaatgagaa aatcaggcta caaccttggt
    56581 ggtgaacagt ctggtcacgt tatcttgatg gattacaata ccacaggtga tggtcaatta
    56641 tcagcagttc aattgactaa aatcatgaag gaaactggta agagcttatc agagttggcg
    56701 gcagaagtaa cgatttatcc acaaaaatta gttaatatcc gagtggaaaa cgtcatgaag
    56761 gaaaaggcca tggaagtgcc agctatcaag gccatcatcg agaagatgga agaagaaatg
    56821 gcggggaacg gccgtatcct tgttcgtcca agtggaacag aacccctctt gcgtgttatg
    56881 gcagaagcgc ctacaacaga agaagtagac tactatgttg ataccatcac agatgtagtt
    56941 cgtgctgaaa ttgggattga ctaaatccta gaaaactaga tgaaaataaa aaattatggt
    57001 acaatagctt ataatattgt agccgatgga gaaagacatg aatcttaaac gtgaacaaga
    57061 atttgttagt cagtatcatt ttgatgcgcg taattttgaa tgggaaaatg aaaatggagc
    57121 tcctgaaacc aaggtggatg tgaatttcca attgctccaa catgaccaag aaaatcaagt
    57181 gacttccttg attgtcatct tgagctttat gattgtattt gataagtttg tcattagtgg
    57241 aacaatctca caagtaaacc atatcgatgg ccgtattgtc aatgaaccaa gtgaattgaa
    57301 ccaagaagag gtggaaacct tggctcgtcc atgtttgaac atgctcaatc gtttgactta
    57361 cgaagtgact gaaattgcat tagacttacc aggaattaat ttggagttct aatatgaaat
    57421 tagctgtttt cacagattcc tctgcttatc tcagtgaaga gaccttgcaa agagaagact
    57481 tgtttgtctt ggatattcct gtcaatattg atggtgagga atatgtcgaa ggcatcaatc
    57541 tgtctgctga ggaattttac caaaaaatgg ctcaggcttc tgaattgcct aagaccagtc
    57601 aaccaagtat tgccaagtta gatgagatct taacttcgct caaagaacaa ggctatacac
    57661 atgccttggg gcttttccta tcttctggaa tttcaggttt ttaccaaaat atccagtata
    57721 tggtcgatga ctatgagggc ttaaccattg ctttcccaga cactttgatt acaagtgctc
    57781 ccctaggcat catggttgaa agcgtcttta attggcgtga tcagggcgat gattttgcca
    57841 gcattcagga taagctagcc attcaaatca gccgtacgtc agcctttatc atggtagatg
    57901 acttggatca tttggtaaaa ggtggacgcc tttcaaatgg ggctgccatt ttgggcaatt
    57961 tgcttagcat taagccaatc ctttatttta acgatcaagg tgtgattgaa gtttacgaaa
    58021 aagttcgtac tgaaaagaag gccaccaagc gcttaattga aattatcaag gaaacaacgg
    58081 cttcaggtca ataccgggtc attgtcattc atgggaatgc tcctgaaaag gctgaagaat
    58141 tgcgtcagca cttgcttgat tttggcttgg gttcggatgt ttcacttgct acatttggta
    58201 gtgtcattgg aacgcaccta ggagcaggaa gtattgctct gggttatatt ccagtgattt
    58261 agttggcgct tctaggctag ttaagatgcc ttgtatctta gaaattgaac acggactacc
    58321 tgcctcttga aaaaagatgc ctgtcttgcc tttcgtggaa agtcagtgcc attccctatt
    58381 tttcagaggc agctaaggtc ctttgtatct tgataattga acacgcctgg aaccctgtgt
    58441 gaaaaagata gttcttccaa gaagtagaca cttcttgatt ggaattccta ttttcacttt
    58501 gtgttcttac ggactttgta tcttagacag gagtagagat gagtattcga gtaattattg
    58561 ccggttttaa gggaaagatg ggccaggctg cttgtcagat ggtattgact gatccagact
    58621 tggacttggt agcagttttg gatccttttg agtctgagtc agaatggcag ggtattcctg
    58681 ttttcaagga taaggctgat ttagctggtt ttgaagcgga tgtctgggta gattttacta
    58741 ctccagctgt tgcctacgaa aatacacgtt ttgctcttga aaatggcttt gctccagtag
    58801 ttggaacgac tggtttcacg agtgaagaaa ttgcagagct aaaagaattt tctcgtgccc
    58861 aagacttggg tggcctgatt gcccctaact ttgccttggg tgctgtctta ctcatgcaat
    58921 ttgcgacgca ggctgccaaa tatttcccaa atgtggagat tattgagctc catcatgaca
    58981 agaaaaagga tgctccgagt ggaacagcca ttaaaacagc tgagttgatg gcagaggttc
    59041 gagagtccat tcagcaaggc gcagcagatg aggaagagct gattgctggt gctcgtggtg
    59101 ctgactttga tggtatgcac atccactcag ttcgtttgcc aggtttggta gcccatcagg
    59161 aagtcatctt tggcaatcag ggagaagggt tgaccctccg tcatgactcc tatgatcgca
    59221 tctccttcat gacaggagtc aatttgggaa ttaaagaagt tgtcaagcgt catgagcttg
    59281 tctatggatt agaacactta ttatgagatt aacgcaaatg ccttctgaat ttcagaaggc
    59341 tttaccagta ttagaaaaaa ttaaagaagc aggctttgag gcttattttg ttgggggctc
    59401 tgttcgagat gcccttctcc ataaccctat ccacgatgtg gatattgcga cgtcttctta
    59461 tccagaagag accaagcaga tttttccgcg aacagccgat atcggaatcg agcatggaac
    59521 cgtcttggtc ttagatgggg atgaggagta tgaggtaaca acctttcgga cagaggatgt
    59581 ctatgtggac tatcgcagac ccagtgcggt ttcctttgtg cgctcgctag aagaagacct
    59641 caaacgccgt gatttcacag tcaacgcctt tgccttggat gagacaggag aaatcgttga
    59701 cttgttccat ggtttagaag atttggaaaa gcaagtcttg cgagcagttg gagtggctag
    59761 tgagcgtttc aacgaagatg ctttacggat tatgcgtggt ttccgttttc aggctagtct
    59821 tggttttgca cttgaaccag aaacatttaa agctatgaag accttgacgc cgcttttgga
    59881 gaacatttct gtagagcgta ccttcgtcga gtttgataaa ctcttgctgg ctccattttg
    59941 gagaaggggc ttggcttcca tgattgagag tcaagcttat gactatctcc ctgatatggc
    60001 atctagccag gacaagctca acagactgtt tgatttggag actgatttta cttttgaatc
    60061 ctctgaacaa gcctgggcgg ctttactatg ggctttggag attgaaaatg cgcagtcatt
    60121 tttgaaatct tggaagacct cacgccagtt tgccaagcaa gttcaggatt tgctgattat
    60181 tttggctctg cgtgaaaatg gagaattgag caagcgagat tgttatcgct ttgacataga
    60241 tttgctttta caggctgaaa atcttcgtca agctcaagga aaagaagtca acccacaagc
    60301 catcacagaa aaataccaaa gcttgactat ccatgacaag aaagagattc agattaatgg
    60361 cggtattttg atcaaggaat atggctatca gccaggccca gacttgggag agattttaac
    60421 agagattgag tttgccattg tcgatggaga attggagaat aatcgtgaag ccatccatgc
    60481 ttacctgagg gagaaaaaat gagtgatttt atcgttgaaa aactaagtaa atccgttggt
    60541 gacaagaccg tttttaggga tatttccttt attatccatg acttagacag aattggttta
    60601 atcggtgtca atgggactgg caagaccacc cttttggacg tcctttctgg tgtttctgga
    60661 tttgatgggg atgtcagtcc tttttcagct aaaaatgatt accagattgg ttacttgact
    60721 caggatcctg attttgatga tagaaagaca gttttggata cggttctatc tagtgaactc
    60781 aaggaaatcc agctcattcg tgagtatgaa ttgattatgc tcgactatag tgaggacaag
    60841 caggcgcgtt tggaacgtgt catggcagag atggactctc tccaagcttg ggaaatcgaa
    60901 agtcaggtca agaccgttct tagcaaattg ggcattcaag acttatctac tcctgttggg
    60961 gaattgtcag gtggtctgag aagacgggta cagttggcac aagtcttact tggcaaccac
    61021 gacctcttgc ttttggatga gccgaccaac catctggata ttgcgattat tgagtggctg
    61081 accctctttt tgaaaaattc taagaagacc gtccttttta tcactcacga tcgttatttc
    61141 ttagacgctt tgtcaacacg gattttcgag ttggatcgtg caggcttgac cgagtaccag
    61201 ggaaattacc aggactatgt tcgcctaaag gcggaacagg atgagcgcga cgcggctctt
    61261 cttcacaaaa aagaacaact ctacaaacaa gaattggcct ggatgcgcag acaaccgcag
    61321 gcgcgtgcga ccaagcagca ggcccgtatc aatcgattcc atgatctgaa aaaggaagtt
    61381 tcaggcagta gtgctgagac agacttgacc atgaactttg aaaccagtcg gattgggaag
    61441 aaagtcatcg agtttcaggc tgtttccttt gcctatgaaa acaagcctat tttgcaagat
    61501 tttaatctct tggtgcaggc caaagaccgt atcggaatcg ttggggacaa tggtgttgga
    61561 aaatcaaccc tgctcaactt gattgcagga agtcttgagc caactaaagg acaagttgtg
    61621 attggggaaa ctgttcgcat cgcctatttc tctcagcaaa ttgagggttt ggatgaaagc
    61681 aagagagtta tcaattacct gcaggaagtg gcagaagagg tcaagaccag tggcggttct
    61741 acgacttcga ttgcagagtt gctggagcag ttccttttcc cacgttcgac gcatggaacc
    61801 ttgattgaga aattgtcagg gggtgagaaa aaacgtcttt atctcctcaa actgcttttg
    61861 gaaaaaccaa atgttcttct tttagacgag ccaaccaatg acctagatat tgcaactttg
    61921 acagtcttag agaatttctt gcaaggtttt gcaggtcccg ttttaacagt cagtcacgac
    61981 cgctatttct tggataaggt agcgaccaag attctcgctt ttgaggatgg caagattcgt
    62041 cctttctttg gtcattacac cgactatctt gatgaaaaag cttttgaaac agatatggcc
    62101 aatcaagtgc aaaaggtcga aaaggaaaaa gtggtcaagg ttcgagaaga caagaaacgc
    62161 atgacctacc aagaaaagca ggagtgggca agtattgaag gtgatattga aaccttggaa
    62221 aaacgtatcg ctgctattga agaggaaatg caggctaacg gctctgactt tggtaagctg
    62281 gctactctcc aaaaagaatt ggatgagaaa aatgaagcac tccttgaaaa atacgaacgc
    62341 tatgagtatc tcagtgaatt tgatagttaa gactattcga aaatcaaagt gcaaactatg
    62401 tcggcttcac attgccgact caagtacagc ctgtgaccgg cttcctaatt tgcactttga
    62461 tttttattga gtataaacga atagaaaaat cccgtctcat gaaaggattt ctctattctt
    62521 ttttggtttc ttgatgaaag atattttgcc aggtttcgtg gcgacgccag atactggtat
    62581 ggatgatacc atctaactca tagcagataa gtttggtttt ttgactgatg gaagtaattt
    62641 gaatgtcctt gatagcagaa tttaactctt ttttggtctt ataagcctct ttatccatct
    62701 gctctccatc ttggcgaata tagacaaaat catcagtcaa gagttcttct agttggtttc
    62761 cttggtcgat caattgttca cgcataagca attttttata gacattgtct aaaatttcat
    62821 cctcagggat aggtgctggt tcgatatgga catcggtatc aaagacgcca aaacgctcct
    62881 ccagcataga ctcgacctga tccgcgattt catggctttc aaaaacagac aagtcaggat
    62941 tcatctctag tgtaatatcc aggtagatgt tgctaccgta ggtgcgacct ctttgcgatt
    63001 tgaccttgct gattttggga atttccatga tagccttttg gtagtcctcg agcaggcggt
    63061 cgtcaaagcc atctgaaaga ctaaaggaag actcgatgaa gatatcatag gcagtcttca
    63121 agataaagaa agtgatgatg atagcaacca gtttatccac aatcggataa ttgaaactac
    63181 tagctaggat ggcaatggcg gttccaagtg aggtaacagc gtcagaaaga ttgtccttag
    63241 cagctgcctt cagcgccttg gagttggatt tcttactgag gcgagtattg tagagataga
    63301 ccacaaacat aatcgctgca gaaatgattc ctagagttgc accaagagga tcaatgaccg
    63361 tttcttcccg actgagaatc ttttgaatgg tatctcttag aacatcgaaa ccgacataga
    63421 acatgatgat agaagtgatc aagcttgcca aatcttcaat cttccaatga ccaaaacggt
    63481 ggtcacggtc tgcaggctgg cgcgccatcc gaatcccgat taagagggcc acatttccaa
    63541 tgatgtccga tacgttatta aaaccatcgg ccaccaaact ggatgaatga aggagatgac
    63601 cagttgctaa tttggctgca gacaagatca aataggtcga aatactgata atggctccac
    63661 gctcagctaa cttgagattt gagatagatt gcttcattca acttcctttc tagtcacata
    63721 gcattctacc attatactgg ttttcaagga aaaattcaaa taaggcagtt tttactcttt
    63781 gaaaactccc caaaatttgg tataatggta ctactcaagg gagtagctgg cagaaacctg
    63841 tgatagtgtc gtcattccga attttatgct gaaaagtatg ctttccggcc ctatcttaaa
    63901 cagcgagact tgttatgatt aacaggtctc tttttgtttg tcgtgaaaag atatgacaga
    63961 aagagagtct gttttgcaca caatgtcaag gaggagacac atgtcaaaag aacaaaaacg
    64021 ccaagcgttt tatactcaga gccctgaaga ggtcttgcag gctgtggatg cgaccgagca
    64081 aggtttgtca tcaagtgagg cggaaaagcg ccttgccgaa tttgggcaca atgaactcga
    64141 agaaggcgag aaacgatcaa tcttggtcaa attcatcgag caatttaagg atttgatgat
    64201 tatcatccta gttgcggcag caatcttgtc agtcgtgact tctggtgggg aagatatcgc
    64261 agatgccatt atcatcctag ctgtggttat catcaacgct gcctttggtg tttaccaaga
    64321 aggaaaagct gaagaagcta tcgaagccct caaatccatg tctagtccag ttgcccgcgt
    64381 tcttcgtgat ggacacatgg cagagattga ctctaaagaa ttggtaccag gcgatatcgt
    64441 tgcccttgaa gcaggtgacg tggtaccagc ggacctacgt ttgctagaag ccaactctct
    64501 taaaattgaa gaagcagcct tgacaggtga atctgtacca gtcgaaaaag acttgtcagt
    64561 cgatcttgcg acagatgctg gtattggtga ccgtgtcaac atggccttcc aaaactcaaa
    64621 cgtaacctat ggtcgtggga tgggtgttgt tgtcaataca ggtatgtata ctgaagttgg
    64681 tcatattgct ggtatgcttc aagatgcgga tgagactgat acaccactca aacaaaactt
    64741 gaacaacctt tctaaggtct tgacctatgc tatcttggtc attgcccttg ttacttttgt
    64801 agtgggtgtc ttcattcaag ggaaaaatcc acttggtgag ttgttgactt ctgttgccct
    64861 tgccgttgca gccattccag aaggacttcc tgctatcgtt accatcgttc tttctcttgg
    64921 tactcaagtt ttggccaaac gacattccat cgttcgtaag ttgccagcag ttgaaacact
    64981 tggttcaact gaaatcatcg cttctgataa gactggtacg ctgactatga acaagatgac
    65041 agtcgaaaaa gtcttctacg atgcggttct acatgactca gctgatgata ttgaactagg
    65101 tcttgaaatg ccactacttc gttcagttgt cttggccaat gatacgaaaa tcgatgtgga
    65161 aggtaacttg attggtgacc caaccgaaac agcctttatc caatatgcct tggacaaggg
    65221 ctatgatgtc aaaggtttct tagagaaata tcctcgtgta gctgaattgc catttgactc
    65281 tgaccgtaag ctcatgtcaa cagttcaccc attgccagat ggtcgtttcc ttgtagcagt
    65341 caagggtgcg ccagaccaac tcttaaaacg ttgtcttctt cgtgataagg ctggggatat
    65401 tgctccgatt gatgagaagg ttacaaatct cattcataca aacaattctg aaatggctca
    65461 tcaagccttg cgtgtccttg caggtgctta taagattatc gatagtattc cagaaaatct
    65521 cacttctgaa gagcttgaaa atgatttaat ttttactggt ttgattggga tgattgaccc
    65581 tgaacgtcct gaagccgctg aggctgttcg tgtggctaag gaagcgggaa tccgtccaat
    65641 tatgattaca ggtgaccacc aagacacagc ggaagccatt gccaaacgtt tgggaatcat
    65701 tgacgcaaac gatacagaag gtcacgtttt aactggtgct gaactcaatg aactgtcaga
    65761 tgaagaattt gaaaaagtcg ttggtcaata ctctgtttat gcccgtgtgt ctccagaaca
    65821 caaggttcgt atcgtcaagg cttggcaaaa acaaggtaaa gtcgttgcca tgacaggtga
    65881 cggtgtcaat gacgcgccag ctctgaaaac agccgatatc ggtatcggta tgggaatcac
    65941 tggtacagag gtttctaagg gggcttctga catgattctt gcagatgata actttgcgac
    66001 tattatcgtc gcagtggaag aaggacgtaa ggtcttctca aacattcaaa agactattca
    66061 gtacctactt tctgctaata ctgctgaagt attaaccatc ttcctatcaa ccttgtttgg
    66121 ttgggatgtc ttgcagccgg ttcatctttt gtggatcaac ttggtaacgg ataccttccc
    66181 agctatcgct cttggtgttg aacccgcgga gcctggtgtc atgaatcata aaccacgtgg
    66241 acgcaaggca agcttcttct caggtggtgt tttgagttct atcatttatc aaggtgtact
    66301 ccaagcagct cttgttatga gtgtttatgg ccttgcgatt gcttacccag ttcatgtggg
    66361 tgacaatcat gctattcatg cagatgccct aacgatggcc tttgcaaccc ttggtttgat
    66421 tcagctcttc catgcctaca atgtcaagtc tgtctaccaa tccatcttga cagttggccc
    66481 attcaagtct aagaccttta actggtccat cttggtatcc tttatccttc tcatggcaac
    66541 aatcgttgta gaaccgcttg aaggaatctt ccacgtaacc aaactagact tgtcacaatg
    66601 gggaattgtt atggctggaa gcttctcaat gattatcatc gtcgaaatcg ttaagtttat
    66661 tcaacgcaaa ctcggttttg acaagaatgc gatttaaggg aggtttcgga tgtcagcata
    66721 tcaattaccg accgtatggc aggatgaagc tagtaatcaa ggagctttta cggggctaaa
    66781 cagacaaaca gcaggtgccc gtttcgaaca aaacttgcca aaaggagaac aagcttttca
    66841 gctttattca ctgggaacac caaatggtgt gaaggttact atcttattgg aagaattact
    66901 agaagctggt tttaaggaag cggcttacga cttgtataag attgctatca tggatgggga
    66961 tcaattcgga tcagactttg tgaagctcaa tccaaattcc aagattccag ccttattgga
    67021 ccagtcaggt actgaagatg taagagtctt tgagtctgct catattcttc tttaccttgc
    67081 tgagaaattt ggagcctttt taccaagtaa tcctgtggaa aaggtagaag ttttgaattg
    67141 gctattctgg caagcaggtg cagcaccttt tctaggtggg ggatttggac atttcttcaa
    67201 ttatgctcct gaaaaattgg aatatcctat taaccgtttt acgatggaag tgaaacgcca
    67261 gttggattta ttggataagg aattggctca gaaaccttat attgcaggca atgactatac
    67321 gattgcagat attgctatct ggtcttggta tggacagtta gttcaagaaa atctttacca
    67381 aggttctgca aaattcttgg atgcctcaag ttatcaaaat ctagtaaaat gggcagaaaa
    67441 aattgccaat cgtccagctg ttaagcgtgg cttggaagta acttatacag aaattaaata
    67501 gcaaaaaagt catcttcgga tggctttttg ctacagttga gggaaagggt ttgcagttat
    67561 cggcttttgt gctataattg ctataatata gtaaaaagca agaggagtgt gaggaagtgg
    67621 aaaagaaaat tgtgaaggat aacttatttt tatctcaagt gtctcagccg gcaagtcagg
    67681 aggaccttta tcttgccaga gatttgcagg atacactctt agcaaatcgt gatacctgtg
    67741 ttggtctagc tgccaatatg attggggtgc agaagcgcgt gattatcttt aatcttggct
    67801 tggttcccgt ggtcatgttt aacccagtgc ttctgtcctt tgaaggatcc tatgaggcag
    67861 aagaaggctg tttgtccttg gtaggtgtga gatcaactaa gcgttatgaa accataaggc
    67921 ttgcctatcg tgacagcaag tggcaggaac agaccattac cttgacaggc ttcccagctc
    67981 agatttgcca gcatgagctg gatcacttgg aaggacgaat catttaggag gaaagcaaat
    68041 gaaacgaata gtctttgaac ttatttttat cgcaacgacc tggtatatct ttttaccgcc
    68101 ccttaacctg accagctggg aatttctctt cttcctctgt gggcatttgt tagttgtggc
    68161 aatcttattt ggctttggca aggggataaa ccttgtcaaa acggttcatg tgcgccacgg
    68221 taaggcggaa gctgccttaa atcttgaggg tttcaaaatc aatcggttag ggaaaattct
    68281 gttagcttcg attggaggaa ttcttctctt ggcagctttg gtttccttgg taacttccag
    68341 catgtttcag gctaaaaatt atgccaatgt agtcacggtt acggaaaaag actttactga
    68401 atttcctagg agtgacacca gtaaggttcc tatcctagat agaagtactg ctgaaaaaat
    68461 tggagaccgc tacttgggtt ccctaaccga taaggtgtcg caatacgtag cggcagatac
    68521 ctatacccaa ttgacaattg atgggaaacc ttatcgggtc acaccactag aatatgcaga
    68581 ccctatcaaa tggtttaaca atcaagccaa gggaatcggt gagtatatca aggtggacat
    68641 ggtaactgga aatgcggatt tggtggactt gaagacacca atcaagtatt cagactcgga
    68701 gtattttaac cgtgatgtca aacgtcacct gcgcttgaag tacccgacca aaatctttaa
    68761 aactccatct tttgaggtgg acgatgaggg caatcctttc tatgtagcaa cggtttacca
    68821 aaagcaattt ggacttgctg ttcctcgtcc tgcttcagtc attatcttgg atgctacaaa
    68881 tggagaaacc aaggaataca gcttatcaga tgttccagaa tgggtggaca ggatctatcc
    68941 agcagaggaa accattgagc aaattaacta caacggcaag tacaaggacg gtttcttgaa
    69001 tgccatgatt tccaagaaaa acgtgaccca gactaccaag ggctataatt acttgtctat
    69061 cggtaatgac atctatctct acacaggtgt gacgtcggct aatgcggatg agagtaatct
    69121 tggtttcatc cttgaaaata tgcgaacagg agaaatcact aagtatagct tggcttctgc
    69181 gacagaagaa tcagcccgtg aatcagcaga aggtgctgtt caggagaaat cctacaaagc
    69241 aaccttccca atcctcatca acctcaatga caagcctctc tacatcatgg gcttgaagga
    69301 caatgctggc ttggtcaaag agtacgccct ggtagacgca gtcgagtacc aaaatgttat
    69361 cgttgctact acagtggaag agatgctcag caagtatgcc aataaaaacg accttgaaat
    69421 tgacaatgca acgacagaaa gcatcaatgg agtagtagca gacctcaaat cagctgttat
    69481 caagggagac actgtctact tctttaaagt tgatggcaag atatacaagg tcaaggcttc
    69541 agtatccgat gaccttcctt accttgaaaa tggtaaaacc ttcgaaggtc aagtaggaaa
    69601 agacaattat ctcaagacct ttaaagtaca ataatactct tcgaaaatct ctagctctat
    69661 ctgcaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt tgctttttga
    69721 ttttcattga gtataaaaaa ggtttattta ataaatatat gttataataa ggtaaattaa
    69781 gcctaatgga ggacaaagaa atgggttttt atttgatggt tgcttcaatg ctactcggac
    69841 tgctcgcttt gaagataggt ttttctcagt tcaaggagaa aaaagataaa ttcttatcta
    69901 tcttaacaag tttagctggc acagcccttg ttctcgtggc tgtctggtta ggatggccca
    69961 aataaataga aaaacctcgg tcaaaccgag gtttttcaaa tgaatttctt ggttgtggct
    70021 aaaaaatatg ctacactatc aatatgaaaa ttttaatccc aacagcaaaa gaaatgaaca
    70081 cagacttgcc aagtatcgag gcaattcctt taaaaccaga aagtcagacc gtgcttgatg
    70141 ccttggctct ctattctgcc agtcaattgg agagtttcta caaggtatca gctgagaaag
    70201 cggcggaaga atttcaaaat atccaagctt tgaaaaggca aactgctcaa cactatccag
    70261 ccttgaaact ttttgatggg cttatgtacc gcaacattaa gagagataag ctgaccgagg
    70321 cggaacaaga ttatcttgaa aatcatgtct tcattacctc ggctttgtac ggtgttgttc
    70381 cagccttgtc acccatggct cctcaccgtt tggatttttt gatgaaatta aaagtcgctg
    70441 gtaagacttt gaagagccat tggaaggcag tctatgatga agctctgaag aaggaagaag
    70501 tgattttctc tctcttgtca tcagagtttg agactgtatt ttctaaggaa atcagagcaa
    70561 agatggtgac cttcaaattc atggaggata gaggcggtca gctgaagatt cactcaacta
    70621 tctccaagaa agcgcgcggg gcctttctaa cagctttaat agaaaatcaa gtacaaactg
    70681 tgggggaagc acgtcgcttg aactttgctg gatttgttta ccgagaagat ttgtcacaac
    70741 cacagggatt ggtttttgta aaggaagtat agaaatcaga tattttgtat ttggcaatat
    70801 gtatcatcag ctgttttagt ttataaatga gaaaaaaagc gaacaagcta gtcttctgag
    70861 tgtcagaaaa gtagtcttgt tcgcttttat tatgttatac tcttcgaaaa tctcttcaag
    70921 ccacgtcagc gtcgccttac cgtatatatg tcactgactt cgtcagttct atctacaacc
    70981 tcaaagcagt gctttgagca gcttgcggct agcttcctag tttgcttttt gatttttatt
    71041 gagtgttagt tacttgatag cttcgaccaa gtcttgagct tgtttttcaa gtgagtttag
    71101 gactgtttct tcaagaacca attttccgtc tgcccaggca gagtcattaa cacgtgcagc
    71161 agtgaaatca ccaacgcctt gtgtacggat aaatggcaag aggtctttgt agatagcgaa
    71221 aagttgatcg tgccctgcat tggctacaga tgatactgtg acaaacttgt cttgaagggc
    71281 agaaacgcca cgtgtatcag acaagtcaag ggcacgagat agccagtcaa gcaagttttt
    71341 cactgtacca gggatagaga agttgtagac tggagagaaa atccagatag catccgcaac
    71401 gagaactgct tcacgagcgg cagctacagc tggatgtgtt gggacttcca aatcttggct
    71461 gaagagaggg agggctgaat aatcaaggta gctaacttcc gctttactag caagtgcttt
    71521 ctcagcttcg agcgccattt ggtggttgaa agaaccttga cgtagtgatc cgacgataaa
    71581 taatactttt ttagacatga tgtgtctcct ttttcttaaa atttcgagaa ctctctcgtt
    71641 gttataaaat atattacaac aaaacaaaag aacttgcaag aaatttgctc agagtttatt
    71701 tgaaaattgt aaaatttcgg aaactctagt catttgtgac tgaaaaagta agaactgttt
    71761 cactttcaaa atcggttttg tttgaaggga gaaatagaat tggttgctca aagcacagct
    71821 ttgaggttgc agataaagct gacgtggttt gaagagattt tcgaagagta ttcttatatt
    71881 cacttgtaat aaagcttaat agatggtaaa atagacgagt gaaaaaaaga caaaacaaag
    71941 caaaaaataa tctactgtgg cagtatggtc tagggatgac gattttgttt gtggttatca
    72001 gtggttcctt tctgtatatg gtttctctta gcatgaaacc ctatcaaaca gctaaaagtg
    72061 aaggagaaaa attagctcag cagtatgcag gattagagca ggtcgatcag gttgatttat
    72121 acaatggctt ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa gaagcgcttg
    72181 ctgtcctgat tggtaaagat gatcataaga tttacgttta tcagctaaat cagggtgttt
    72241 cacaagaaaa agcagaaacg gtttctaagg aaaagggagc tggcgaaatt gacaagatta
    72301 tctttggtcg ttatcaagat aagccaatct gggaagtcaa gtcaggatct gatttttatc
    72361 tagtagattt tgaaacagga gcattggtca acaaggaggg cctatggaat tatccaaccg
    72421 tgttttagaa atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca aagcactgaa
    72481 ggctgagggt agagatattt tgtctctaac cttgggtgag ccagatttca ctactcccaa
    72541 aaatatccaa gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt tttatacagt
    72601 aacctcaggt ctgccagagc ttaaggcggc ggtcaatagc tactttgagc gcttttacgg
    72661 ctattctgta gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt ctctctatac
    72721 cttctttatg gctgtggtca atccaggtga tgaagtcatc atcccaaccc catactgggt
    72781 tagctatgga gatcaggtca agatggcaga aggcgttccc gtctttgttt ctgctaagga
    72841 agacaatcac tttaaggtga ccgtagagca gttagaagca gctcgcactg acaagaccaa
    72901 ggttttggtg ctgaattcgc catctaatcc cacaggtatg atttacaccc gtgaggaact
    72961 cttggcaatt ggaaactggg ctgtagaaaa tgatattctc atcctagcag atgatatcta
    73021 tggccgcttg gtttataatg gtcatgagtt cacaccgatt tctagcctat cggaagcgat
    73081 tcgcaagcaa acagtggtca tcaatggtgt gtctaaaacc tatgccatga ctggttggcg
    73141 gattggttat gccgttggag aagcagacat tatcgctgcc atgtccaaga ttgcaggtca
    73201 aacaacttcg aatccgtcag cagtagccca atatgcagca gttgaggctc tatcaggtga
    73261 gcaagatact gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata ccatctatcc
    73321 cctccttgca gaagtgccag gatttgaagt ggtcaaaccg caaggggcct tctatctctt
    73381 cccaaatgtc aaaaaggcca tggagatgaa aggctacacg gatgtgacag actttacaac
    73441 tgttatctta gaagaagccg aagtggcctt ggtaacagga gctggatttg gagcaccaga
    73501 aaatgtccgc ctcagctatg cgacagacct agacacgctt aaagaagcag tcgaacgctt
    73561 gaaagcattt atgggtagtg agaatgattg atcattttga gattaaggta aaggatttac
    73621 aaatttcaga aggattttat aggagttttc tcgctccttt ggactataaa ttggctttta
    73681 agactagttc tctaattagt tttctatccc cgaacagccc tcatcctggt ggtgattttt
    73741 ggctgactca gggaacacaa gatcctgttc attttgcttt tttagcagaa aataaggaag
    73801 aagttcaggc ttgttatgag gctggcttag aggcaggtgg gcgagacaat ggggctcctg
    73861 gttatcgaag tgagcatccg atttactatg ctgcttttat gattgacctg gatgggaaca
    73921 atatagaggt ggtttgccat aaagaataaa aaagaaaagg aaaaataatg acaaaacgtg
    73981 taacgattat tgacgtaaaa gactatgttg gtcaggaagt gacgattggc gcttgggttg
    74041 ccaacaaatc aggaaaaggg aaaatcgctt tcttacaatt gcgtgatgga acagccttct
    74101 ttcaaggtgt ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa gtgggacttg
    74161 agaagtttga tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg acaggtattg
    74221 tcaaagagga cgaacgttct aaatttggct atgagttgga catcacagac atcgaagtga
    74281 tcggtgaatc tcaagactac ccaatcacac caaaagaaca cggaacagac tttttgatgg
    74341 ataaccgtca cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa atccgtaacg
    74401 ctattatcta tgcaacttat gagttctttg acaagaacgg ttttatgaag tttgacagcc
    74461 caattctttc aggaaatgcg gcagaagatt ctacagaact ctttgaaact gactacttcg
    74521 gaacgccagc ctacttgagc caatcaggtc aactttacct agaagcaggg gctatggctc
    74581 ttggtcgtgt ctttgacttt ggtccagttt tccgtgctga aaaatcaaaa acacgccgtc
    74641 acttgactga gttctggatg atggatgctg agtactcata cttgacacat gatgagtcgc
    74701 ttgacttgca agaagcttat gtgaaagctc ttctacaagg tgttcttgac cgcgcgcctc
    74761 aagccttgga aaccttggaa cgtgatacag aactcttgaa acgctacatt gcagagccat
    74821 tcaaacgtat cacttacgat caagccattg acctcttgca agagcatgaa aatgatgaag
    74881 atgctgacta cgagcatctt gagcatggtg atgactttgg gtcaccacac gaaacttgga
    74941 tttcaaacca ctttggtgtg ccaacatttg tcatgaacta tccagcagcc atcaaggcct
    75001 tctacatgaa accagttcct ggaaatccag agcgcgtgct ttgtgcagac ttgcttgctc
    75061 cagaaggcta tggagaaatt atcggtgggt ctatgcgtga ggaagattac gatgcccttg
    75121 tcgctaagat ggatgaactt ggcatggatc gtacagaata tgaattctac cttgaccttc
    75181 gtaaatacgg tacagttcca cacggaggat ttggtatcgg tatcgaacgt atggtaacct
    75241 tcgcagcagg aacaaaacat atccgtgaag ctattccatt cccacgtatg ttgcaccgta
    75301 tcaaaccata agaacaggaa aacgcccatg tggcgttttt tcgaattcta gtgtttttac
    75361 ttgcgtaaaa aaattttttc tagtataata gtttattgtg agcgaacctc acttacccct
    75421 tgcaaagtct tggggtcatt agaccaaaag gaggaacata tcaatggcta aatacgaaat
    75481 tctttatatc attcgtccaa acattgaaga agaagctaaa aacgctttgg tagcacgttt
    75541 tgactctatt ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt gggaaaaacg
    75601 tcgtcttgca tacgaaatcc aagatttccg tgaaggactt taccacatcg ttaacgttga
    75661 agcaaatgac gatgcagctc ttaaagagtt tgaccgtctt tcaaaaatca acgctgacat
    75721 tcttcgtcac atgatcgtca aaattgacgc gtaagaaggt aaactatgat taacaatgtt
    75781 gtacttgtag ggcgtatgac acgtgacgct gagttgcgtt ataccccatc aaatgtagca
    75841 gttgcgactt ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg tgaacgtgag
    75901 gctgatttta tcaatgtcgt tatgtggcgc caacaggctg aaaatcttgc taactgggct
    75961 aaaaaaggct cacttatcgg ggtgacaggt cgtatccaga ctcgtagtta cgataaccag
    76021 caaggacaac gtgtctacgt gacagaggtc gtggctgaga atttccaaat gttggaaagc
    76081 cgtagtgtgc gtgagggcca cacaggtgga gcttactctg caccaactgc aaactattca
    76141 gcacctacaa attcagtacc agacttttca cgtaatgaaa atccatttgg agcaacaaac
    76201 ccattggata tttcagatga tgatttacca ttctaatgga caactaaact tataaaggag
    76261 aaaaaacatg gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag ttgattacat
    76321 cgcagcaaac aaaattgaat atgttgatta caaagatact gagcttctta gccgtttcgt
    76381 ttcagaacgt gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta aaaaccaacg
    76441 taaagtaaca acagctatca aacgcgctcg cgtaatggct ttgatgcctt tcgtaaacga
    76501 agattaaaga aaagacccgg ttgggtctct ttttcatgag cttgaaaaca agaaagcgaa
    76561 ttaagacccc aacgggtctt ttttcacaag ctttgaaatg agagagcgag ttaggctcag
    76621 tggctccctt tttacgagtt tgaaaacaag agaacacatt aaaagcacga tggagctttt
    76681 tcataaatat gtcttttttc tcatccaaga aattaaaata aaaatgataa actttttgaa
    76741 aataggggat ttgcctactt tatgatataa tggaaagagt tagattgaaa gaggtagtga
    76801 gatggacgcg aaattaagat acaaggcaaa gaagatcaag attgtctttt ttgatattga
    76861 tgatacattg cggaattcaa agacagggtt tattccaact acaattccca ctgtttttaa
    76921 acagttgcgt gaaaaaggaa ttttaacagg aatcgcctct ggacgtggca tttttggtgt
    76981 tgttccagag attcgtgatc tcaagcctga cttttttgta actttgaatg gagcttatat
    77041 cgaagataaa aaaggtcagg tcatttatca gcatcagatt gaaaagtcag atgttgagga
    77101 gtatatctct tgggctaagc aagaaggaat tgaatatggc ttggttggga gtcatgatgc
    77161 caagttgtcg actcgcaccg atatgatgag tgaagctatc aatccaattt atcccgactt
    77221 agatgtagat cccgatttcc atgaaaaaga agatatctat cagatgtgga cttttgaaga
    77281 taagggagat gacttgcact tgcctgacag tctctcagac aaacttcgca tggttcgttg
    77341 gcatcaacat tcgtctgata ttgtgccgat ttcaggctcc aaagcgacgg gggtggaaaa
    77401 ggttgtggaa caccttggct tgaaaccaga gaaggtcatg gtttttggag atggtctcaa
    77461 cgacttggaa ctctttgatt atgctggaat cagcgttgcc atgggaattt ctcatgataa
    77521 aatcaaagaa aaagcagatt atattacaaa aacattagaa gaagatggca tttttgatgc
    77581 cttagaagta tttggtatgg tagaaaaaga attgcatttt ccacaagtag acattgaaac
    77641 agtagaaggt cctcttgcga ctattaagac caatcacgga gacttacgta tcaagctttt
    77701 ccctgaacat gctcctaaaa cagtggctaa ctttgtatct ctttcaaaag atggctacta
    77761 tgatggtgtc attttccacc gtattatcaa ggactttatg atccaaggtg gagacccaac
    77821 tggaactggt atgggtggcg agtcaatcta cggcgaatct tttgaggatg aattctcaga
    77881 agagctttac aatatccgtg gtgctctttc catggcaaat gctggtccaa ataccaacgg
    77941 cagccagttc tttatcgtgc aaaaccaaca cctaccttat tcgaagaaag aaattactcg
    78001 tggtggttgg ccagaaccga ttgcagaaat ctatgccaat caaggtggga cacctcacct
    78061 agaccgccgt cacacggttt ttggtcagtt agctgatgaa gcatcttacg ctgtcttgga
    78121 tgccattgct gctgttgaga caggagctat ggacaagcca gttgaagatg ttgtaattga
    78181 aactattgaa atcgaggact aagatgaaaa tcggtgataa gctaaagggg cgtattacag
    78241 ggattcagcc ctacggtgcc tttgttgagt tagagacggg tgatacgggg ctgattcaca
    78301 tttcagaaat tcggacagga tttattgaaa atattcatga aaccttgaaa gtcgatgaag
    78361 aggttcaagt tcaggtagtg gatttagatg aatttacggg gaaagccagt ctttctatcc
    78421 gcactttgga ggaagaaaag taccagtttc ctagacggag acgcttttca agcgaccgct
    78481 ttaactacgg ttttgctccc tttcgacgaa tgctaccaat ctggactgga gaagccctgc
    78541 accatttaaa aaagaagaag tagtttagag ttttatattt tttgtaatgt taatatgaat
    78601 ttgctataat aggaccatgg aagaagaaca attattaaaa tcaggagagc gcattaacca
    78661 gctcttttcg acagatatca aaatcattca aaatagagag gtttttagct attcggtgga
    78721 tagtgttctc ttatcacgat ttccacgttt tcctaagaag gggttgattg tggatttctg
    78781 tgctgggaat ggagcagtgg ggctttttgc tagcactcgt actcaagcac agatattgtc
    78841 tgttgagatt caggagcgtt tggcggatat ggctgaacgc tctgtccgtt tgaatggatt
    78901 agaggagcaa atgcaggtca tctgcgatga tttgaaaaat atgcctgctc acattcaggg
    78961 gagtaaggtg gatatgattt tgtgtaatcc accctatttc aaggtgaatc cttattctaa
    79021 tctgaacgag agtgaacatt atctcttggc tcgacacgaa atcacgacta atttggaaga
    79081 aatctgtcgt agtgcccaga gtattctcaa gtctaatggg cgtttggcca tggttcatcg
    79141 tcctgatcga cttctggata ttttggatac gttaaaacga cataatctag cccctaagcg
    79201 cctgcagttt gtttatccaa aaagagaaaa ggaagccaat atgcttttga ttgaggcgat
    79261 caaggatggc tcaacaagtg gctttaaggt cttacctcct ttgattgtcc acaatgatga
    79321 tggctcttat acgcccgaaa tcgaagagat ttattatgga tcataaggct tatatgtacg
    79381 ttctggagtg tcgtgatgga tcctactata taggctatac gactgatatg agaagacgcc
    79441 tcgctatcca caatagtggg aagggagcca aatatacacg agcacgcttg ccagtcaaac
    79501 ttatctatgc tcaaggtttt gccagtaagg aagaagccat gtcggctgaa gctcttctca
    79561 agcgtaagaa gaggccacag aaggaagaat ttttatctga aaatcaagat agaaatttac
    79621 tcagttattt tgaagaatcg tggggagtcc tttgactcct cttacctttg tcaaaaagcg
    79681 aaaaaaatgc tacaataaag aaaataaaca aaatgaggta ttatcatgtc caagattcta
    79741 gtatttggtc accaaaatcc agactcagat gccatcggat catctgtagc ttttgcctac
    79801 cttgcaaaag aagcttacgg tttggatacg gaagctgttg cccttggaac tccaaatgaa
    79861 gaaacagcct ttgtcttgaa ctattttggt gtggaagcac cacgtgttat cacttctgcc
    79921 aaagcagagg gggcagagca agttatcttg actgaccaca atgaattcca acaatctgta
    79981 tcagatatcg ctgaagtaga agtttacggt gttgtagacc accaccgtgt ggctaacttt
    80041 gaaactgcaa gcccacttta catgcgtttg gagccagttg gatcagcgtc ttcaatcgtt
    80101 taccgtatgt tcaaagaaca tggtgtagct gtgcctaaag agattgcagg tttgatgctt
    80161 tcaggtttga tttcagatac ccttcttttg aaatcaccaa caacacaccc aacagataaa
    80221 atcattgctc ctgaattggc tgaattggct ggtgtgaact tggaagaata tggtttggca
    80281 atgttgaaag ctggtaccaa cttggctagc aaatctgctg aagaattgat tgatatcgat
    80341 gctaagactt ttgaactcaa cggaaataat gtccgtgttg cccaagtgaa cacagttgac
    80401 atcgctgaag ttttggaacg ccaagcagaa attgaagctg caatgcaagc tgccaacgaa
    80461 tcaaacggct actctgactt tgtcttgatg attacagata tcgtcaactc aaactcagaa
    80521 atcttggctc ttggtgccaa tatggacaag gtcgaagcgg ctttcaactt caaacttgaa
    80581 aacaatcatg ccttccttgc tggtgccgtt tcacgtaaga aacaagtggt acctcaattg
    80641 actgaaagct ttaatgcgta agattttggg tgtcagctca aaatcggaaa gtctagtttg
    80701 ccttatatcg aaaggagttt cggctccttt tttctaggag tgaagtatgt tagaaaatgg
    80761 cgatttgatt tttgtgagag atgggtcaga catgggacag gccatccaga cttccacagg
    80821 taactatagc catgttgcca tttatttgga tgggatgatt tatcatgcta gtggacaggc
    80881 tggtgttgtc tgtcaagaac cggcagactt ctttgagtcc aatcatttat acgacctcta
    80941 tgtttaccca gaaatggata tccagtcggt gaaggaaaga gcttgcaaac atcttggagc
    81001 accctacaat gcttctttct atccagatgc acctggtttc tactgctccc agtatatagc
    81061 agaaatccta cctatttttg aaactattcc tatgaaattt ggagatgggg agcaggagat
    81121 tagtgatttt tggagggagt attacataga actaggtctg cctgttcctc tgaaccaagc
    81181 tggtaccaat cctagtcagt tggcagcatc gcctctgtta caatgtaaag aaaggaatct
    81241 tcatgattca gatttttaat ccatctcgtt tgacgagaca gccatttttg gagaattgat
    81301 ccgctatctg gaccagtatg aggatgtgat tctacgggaa attaaggctc aatttccaga
    81361 tgttgcagtt gataaactca tggaagagta tataaaggca ggcttgattc tacgtgaaaa
    81421 taagcgctat tacctcaatt ttcctacgct tgaatcactt gatagtcttg aactggatca
    81481 agagattttt gtcagagaag ctagtccggt ctatcaagcc ttgttggagc agagttttga
    81541 gacggaattg cgcaatcaaa tcaatgcagc tattttagtt gaaaagacgg actttgcgcg
    81601 cattaaaatg actctgtcca attattttta caaggtcaaa cagcagtatc ctttgacaga
    81661 aaaacagcag gagctctatg acattttagg agatgttaat cctgagtatg cactcaagta
    81721 tatgacggct tttttgttga aatttctcaa aaaagaccag cttatgcaga aatgccgtga
    81781 tatctttgtg gacagtttgg ttgtcttagg ctatattgtg caaaatgaag atggaaagta
    81841 tgagttggct atcgattttg ataaggagag attaactttc tacttagcgt gatttcttgt
    81901 ttctgagtac attgtttgac tttccttagt attcggtata aactatatgt aaccggtaac
    81961 acatatcgga ataaactaaa ggagacaatc atatgtcact tgaaaacaaa ttggaacaag
    82021 caacaggcgc tgtcaaagaa ggttttggta aagttactgg agacagcaag acagaacttg
    82081 aaggagctgt tgaaaaaaca gttgctaagg caaaagacgt tgtagaagac gcaaaaggtg
    82141 ctgtagaagg tgccgttgaa ggtttgaaaa acgtttttac taaagaatag gaaaaaatca
    82201 agggtttcat tttcccttga ttttttctat tcttataaat aattttctgc gacggctgta
    82261 tctcctgggt aggattcttt cttgccctgg atgatttggt aacaatcggc tcccttaccc
    82321 gcaataataa ctgcatctaa ttcgtgattt gtgatagcca ttgccgcctt gatggcttct
    82381 tggcgatccg caatcttctc aacaggatga ttgatgtagc tactaatttc atctgcaatg
    82441 gccattgggt cttcatagtt agggtcatca gcagtcagaa agacttgaat ctcagggtgt
    82501 tgattgagga ggaggccaaa gtccttacga cgactttctc ccttgtttcc tgttgatccc
    82561 agaaccagag caatctttcc ggtttgatga gtttcaacca cattgatgag ttttttcaga
    82621 ctatccccat tgtgggcata gtcgatgaag accttggctc catttttctg agtgaggact
    82681 tccatacgac caggaacgcg ggttgcagcg atgccttttt tgatgtcctc aagacttgct
    82741 ccgagacgga gacaagcaag tccagcagca actgcatttt cttggttgaa gttgccaatg
    82801 agttggatat cataatctcc agcgagttta cccgtagctg aaaagctaaa ggctttggaa
    82861 ttctcgattt ggttatcaaa ttggctacca tagaaatcat ggtcttgatc ttcaacctgt
    82921 tctttcaaga ctgagaagtg gtccatgtca ctgttaatga tgactgctcg gctattttcc
    82981 atcaagagac gcttgtggta gaaatagtct tcaaagctag ggtgttcaat cgggccgata
    83041 tggtctgggc tgatattgag gaaaactccc acatcaaagg ttagaccata gacacgtctg
    83101 accagatagg attgactgga gacttccatg atgaggtggg tacggtcatt ttgcacagcc
    83161 tgattcatca tgtcaaagag gtcaatactc tcaggggttg tcaacgctga cttaaagaaa
    83221 gtctcgccat caagagttgt gttcatggtc gacaacatag caggtcgatg cccttgagat
    83281 aagatgttat aggcgaaata ggctgctgtt gtcttaccct tagtaccagt aaaggcaagg
    83341 agtttgagtt tttcctgtgg attaccatag aactccatgg caatcaaact catggctttc
    83401 tttatatcgt tcacaatgat gacagggata ccgacttcgt agtccttttc agctacatac
    83461 caagctaagc cttgtgttat agcagaaaga aggtattctt ttttaaaggc agcgcctttt
    83521 gcaaaaaaaa gagtgtcttc tgttactttt cggctatcgt agctgatgct atcaaaaaca
    83581 actttgctgt agttgtagtg gtaatgacct tggtcaataa tttcgcgaaa aaggccatct
    83641 ttctttaaaa tatctaatac agtttcaatt tttatcatac tttctattgt aaaccgaaag
    83701 tcgcaaattt acaagtaaca aggaaaagtt tataatggaa gataaggagt ttttcctagt
    83761 tatcaaaatt gaatgaggaa tctatgtcgc acgaaaacaa tcaccagcag gcccagatgt
    83821 tacgggggac tgcttggcta acggctagta actttatcag tcgcctactc ggggctgttt
    83881 acattatccc ttggtacatc tggatggggg cttatgcagc taaggcaaat ggtctcttta
    83941 ccatgggtta caatatctat gcttggttct tgttggtttc aacagcgggg attccagttg
    84001 cggtggccaa gcaagttgcc aagtataata ccatgcgaga agaagaggat agctttgccc
    84061 tgattcggag cttcttaggc tttatgacag gactaggcct ggtttttgct ttagtcttgt
    84121 atgtctttgc tccttggcta gcagacttgt ctggtgtggg caaagacttg atcccaatca
    84181 tgcaaagctt ggcttgggga gtcttgattt tcccgtctat gagtgttatc cgaggatttt
    84241 tccaagggat gaataacctc aaaccttatg ccatgagcca aattgctgag caggtcattc
    84301 gtgttatctg gatgctccta gcaaccttta tcattatgaa gctcggttca ggagattatc
    84361 tagcagccgt tacccaatca acctttgctg cctttgtcgg tatggtagcc agttttgcag
    84421 tcttgattta tttccttgcc caagaaggtt cactcaaaag agtctttgaa acaggagata
    84481 agattaacag taagcgtctc ttggttgata ccattaagga agccattcct tttatcctga
    84541 cagggtctgc catccagctc ttccagattt tggatcagct gacctttatc aatagtatga
    84601 gctggtttac caactacagc aatgaggact tggttgtcat gttttcttat ttctcagcca
    84661 atcctaataa aatcacgatg attttgattt ctgtaggggt ttcgattggg agtgttggtt
    84721 tgccactttt gacggaaaac tatgtcaagg gggacttgaa agcagcttct cgtctggttc
    84781 aggacagtct caccctactc tttatgttct tgctaccagc aacggttgga gtggttatgg
    84841 taggagaacc tctatataca gtcttctatg gtaagccaga tagtttggct ctgggcttat
    84901 ttgtctttgc agttttgcag tctattattt taggcttgta catggtcttg tctccaatgc
    84961 ttcaggccat gttccgcaac cgcaaggccg ttctctattt tatctatggt tctattgcca
    85021 agctagtctt gcaactacct accatcgccc tcttccacag ttatggtcct ttgatttcaa
    85081 caaccattgc tctcatcatt cctaacgtct tgatgtatcg ggatatttgt aaagtaactg
    85141 gtgtcaagcg caaggtgatt ttgaagcgaa ccattttaat cagtttgctg accctagtca
    85201 tgtttctgtt aataggaacc atccagtggc tgttaggatt tttcttccaa ccaagtggac
    85261 gtttgtggag cttcttttat gtagctcttg tcggtgccat ggggggtgga ctttatatgg
    85321 ttatgagtct gcgtacctat ttattagata aggtaatagg aaaagcccaa gcagatcgcc
    85381 tgcgagcaaa atttaagctt tcgtaaggta gcatttataa ataaaaggaa taagttgaac
    85441 aatcttttag gagaacttga aacttattcc ttttttagcg tcaaaatagc taaaattatc
    85501 tttcaaaaat agaaaatgag gtttttttga ttttttggaa aaaacaattg actaaacaaa
    85561 ccaagagttg tataataaaa caaatattta aagcaggagg ttctggaaat gaaaaagtct
    85621 aagagcaaat atctaacctt ggcaggtctt gtcctgggta caggagtttt attgagcgcg
    85681 tgtggaaatt ctagcactgc atcaaaaacc tataactatg tttattcaag tgatccatct
    85741 agtttgaact atctagcaga aaaccgcgca gcaacatccg atattgttgc aaatttggta
    85801 gacgggttat tagaaaatga ccaatatggg aatattattc catcattagc agaggattgg
    85861 actgtttctc aggacggttt gacctatacc tacaaacttc gtaaggatgc caagtggttt
    85921 acttctgagg gagaagaata tgcgcctgta actgcccagg attttgtgac aggtttgcaa
    85981 tatgcagctg ataaaaaatc agaagctttg tatctagtgc aggactctgt tgctggtttg
    86041 gatgactata tcactggtaa aacaagcgac ttttcaactg tcggtgtcaa ggcacttgat
    86101 gaccaaacgg ttcaatatac tttggttaaa ccagaacttt actggaattc aaaaacactt
    86161 gcaacgatac tttttcctgt taatgcagat ttcctgaaat caaaagggga tgattttggg
    86221 aaggcggatc catctagtat tttgtacaat ggacctttct tgatgaaagc acttgtctca
    86281 aaatctgcta ttgaatataa gaaaaaccct aattactggg atgctaagaa tgtctttgta
    86341 gacgatgtga aattgaccta ctatgatggt agcgaccaag aatcactgga acgtaatttt
    86401 acagctggtg cttatactac ggctcgtctt tttcctaaca gctccagcta tgaagggatt
    86461 aaagaaaaat acaaaaacaa tatcatctat agtatgcaaa attcaacttc atatttcttt
    86521 aattttaacc tagataggaa gtcttacaat tatacttcta aaacaagtga cattgaaaag
    86581 aaatcgaccc aggaagcagt tctcaataaa aacttccgtc aggctatcaa ttttgctttt
    86641 gacagaacat cttatggggc tcagtctgaa gggaaagaag gtgcaacaaa gattttgcgt
    86701 aacctagtgg ttcctccaaa ctttgtcagt atcaagggaa aagactttgg tgaagttgta
    86761 gcctctaaga tggtcaacta tggtaaggaa tggcaaggta tcaactttgc ggatggtcaa
    86821 gacccttact acaatcctga gaaagccaag gctaagtttg cggaagctaa gaaagaactc
    86881 gaagcaaagg gtgttcaatt cccaatccac ttggataaga ctgtggaagt aacagataaa
    86941 gtaggcatac aaggagttag ttctatcaaa caatcaattg aatctgtttt aggttctgat
    87001 aatgtagtga ttgacattca gcaattaaca tcagatgagt ttgacagttc aggctacttt
    87061 gctcaaacag ctgctcagaa agactatgat ttatatcatg gcggttgggg acctgattat
    87121 caagacccgt caacctatct cgatattttt aatactaata gtggaggagt tctacaaaat
    87181 cttggactag agcctggaga agccaatgac aaggctaagg cagttggact ggatgtctat
    87241 actcaaatgt tggaagaagc taataaagag caagatccag ccaaacgtta tgagaaatat
    87301 gctgatattc aagcttggtt gattgatagt tctttagttc ttccaagtgt ttcgcgtggg
    87361 ggaacaccat cattgagaag aaccgtacca tttgctgctg cctatggttt aaccggtaca
    87421 aaaggggttg aatcatataa atacctcaaa gtacaagata agattgtcac aacagacgaa
    87481 tatgcaaaag ccagagaaaa atggttgaaa gaaaaagaag aatccaataa aaaagcccaa
    87541 gaagaattgg caaaacatgt caaataaaat ctaattgtag ataagtttgt gtaagaagtc
    87601 tttgtgctta aaaacgcata atatcaggta tataaaatcc tagatgttat gcgttttgtt
    87661 ataggaagat ttattagatt ttatcctcaa attgagttat tcccgacttt atccgttgaa
    87721 atattataag gagtatttat gaaattaaaa ttattaagag tagatactaa ggtgattatg
    87781 gggagtttct tacttgttct gtctagtcta cttgctttgt tgcttcccct tatcttaaag
    87841 ggtttaatag atgggagttc tattgaaaat ataggttcca aagtatttca atcgtttttg
    87901 atttttattg gtcaagcctt gttttcttct attggttact atctgtttag tcaatcgggt
    87961 gaaaaaaaga tagcaaaaat caggaaaaaa gtgatagagg ggttgattta tgcagagaaa
    88021 tccttctttg ataagagcca aagtggggag ttgacttctg ccattgtcaa tgacatgagt
    88081 gtcattcgtg agtttttaat tacgactttc ccaaatatta ttctgagttt agttatggta
    88141 cttggttcca ttgtagtctt atttagtctt gattggaatc tttctctact tttattcatc
    88201 actcttcctt gtatgatgtt tattatcttg cccctttcca atatcagtga aaagtatagt
    88261 cgtcgtttac aggaggaaat ttaacagggc aattgactga aaagattcaa gaacatgaat
    88321 taattaagac taaccaagca gagaaaagtg tacaggatgt tttggataat tgtattgaaa
    88381 gggtacaaaa caattcactg aaatcagata gggttacttc ttttgagacc tcgtttgctc
    88441 tcttatttat ctttgcgact atagttgtga tgctaaccta tgggggttat cgggtcagcg
    88501 caggatatat atctgtggga accttggttt cgtttttgat ttacctcttt caattactta
    88561 atcctattag taatatagct aattttgtaa ctgtttattc taggagcaag ggatcttcag
    88621 ttgcactgga taacttgctt gcagttccta aagaaaaatt tgagggagga aaatcggtat
    88681 caggacaagg gttgaatttt aaccatgtct attttggtta tgatgaaaat cgacctgtct
    88741 taaaggatat tacttgttca attttcaagg ggcaaaaatt gcttttgttg gaccatctgg
    88801 atcaggaaaa tcaacgattg tgcgtttgtt agagcggttt tataaaccgc tttcaggaga
    88861 tattctaatg gagcaatcaa gtatatatga ttttaactta aaagaatgga gaagtaaaat
    88921 cgcttgggtt tcacaaaata atgcagtctt atctggcagt attcgtgaca atctttgtct
    88981 cggtttgaat cgcttagtaa ctgatgatga attgatgaaa gtgctagact tagtatcact
    89041 aggtgatgag attcgctcca tgaaagaggg actagatact gaagttggtg aacgcggacg
    89101 attcttgtca ggggggcaaa gccaaagact tcaaatagct agaacctact taaaagatgc
    89161 tgaaattctt atatttgatg aagctactgc taatcttgat gcggattctg agtatgcgat
    89221 tatcagtagc ctctattctg tattaaagga gaagacggtt gtgattatag cgcatagttt
    89281 gtcaacggta aaagatgtgg attgtatttt cttcttagag gaggggaaaa tcactggctc
    89341 aggaactcat aaggaactac tggaaaatca tgagcgttat gctcgttttg tgcaggagca
    89401 aatgatagag tgaagtgtct tttgagattc accattttat agtctattaa agggagcagg
    89461 aaaaactccc tttttatata gtttgaaact ataactagct cttgaaaaga agaaaatgag
    89521 ttgatgaaaa taagtggtac aatagttact atagatttgg aggtattgta tgagcaagga
    89581 attacacatt aacacaattt tggcccaggc gggtattaag tcagatgaag cgacaggtgc
    89641 attggtgaca ccgcttcatt tttcaacgac ctatcagcat ccagagtttg gtcgatctac
    89701 tgggtttgac tatacgcgca ctaaaaatcc aactcgtagt aaggctgagg aagtcttggc
    89761 ggctattgag tcagcagact atgccttagc gactagctca gggatgtcag ctattgtact
    89821 ggcctttagc ggctttccag taggaagtaa ggtcttggca gtgcgtgatc tttacggcgg
    89881 ttcttttcgc tggtttaacc aagtggagca ggaaggtcgt ttccatttta cctatgccaa
    89941 tacagaagaa gagttgattg ccgagttaga aaaggatgtg gatgttctct atatcgaaac
    90001 cccaaccaat cccttgatgt tggaatttga tatcgaaaaa ctagcaaaat tggctcatgc
    90061 taagggtgcc aaagtggtgg tggacaatac cttctatagc cctatctacc aacgtccgat
    90121 tgaagatgga gcagatatcg ttctccattc agcaaccaag tatctagcag gccacaatga
    90181 tgtcttggct ggagtggttg tgaccaatag tttagaacta tacgagaagc ttttttacaa
    90241 tcttaataca acaggggcag tcttgtctcc atttgacagc tatcagttgc ttcgtggtct
    90301 caagaccttg tctcttcgta tggagcgctc aacagctaac gcccaagaag tggttgcctt
    90361 tttgaaggat tctccagcag ttaaggaagt tctctacact ggtcgtggag gcatgatttc
    90421 ctttaaagta gccgatgaaa cacgcattcc tcatattttg aacagtctca aggtcttctc
    90481 ttttgcggaa agtttgggtg gagtggaaag tcttattact tatccaacga ctcaaactca
    90541 tgctgatatt ccagcagagg tacgccattc ttatggtttg acagatgacc tcttgcgttt
    90601 gtctattggg attgaggatg ctagagattt gattgcagat ttgcgccaag ccatagaagg
    90661 ataagacaaa gatgggaaaa tatgatttta caagcctgcc caaccgttta gggcaccata
    90721 cctataaatg gaaagaaaca gaaacggata gtgaagttct accagcttgg atagcggata
    90781 tggactttgt ggtcttgcct gaaatccgcc aagccgtgca aacttacgca gaccaactgg
    90841 tttatggtta tacctatgcc agtgaagact taattaagga agttcaaaag tgggaagcta
    90901 cacaatacgg ttacaacttt gacaaagagg ctcttgtctt tatcgagggt gtggtaccag
    90961 ccatctcaac agctattcaa acctttacaa aagaaggcga ggcggtttta attaacacgc
    91021 ctgtctaccc accctttgct cgcagtgtca agttgaataa tcgtagattg attactaatt
    91081 ccttagtgga aaaggatggt ctgtttgaga ttgactttga ccaacttgaa aaggatttgg
    91141 tggaagagga ggttaaactc tatattcttt gcaaccctca caatcctggt ggacgtgttt
    91201 gggaaaaaga agtgttggag aagattggcc aactctgcca aaaacacggt gttttgttag
    91261 tttcggatga gattcaccaa gatttgaccc tctttggtca caaacaccag tctttcaata
    91321 ccatcaatcc tgccttcaaa aattttgcta tcgtcttgag cagtgccact aaaacattta
    91381 atattgctgg aacaaaaaat tcctatgcag tcattgaaaa tcctaagttg agactagctt
    91441 tccagaaacg cctgttggcc aataatcagc atgaaatttc aggcttgggt tatttggcga
    91501 cagaagctgc ctatcgatac ggtaaagatt ggctagagga actcaagcaa gtctttgaag
    91561 accacatcaa ttatgtggtg gatctatttg gaaaagagac taaaatcaag gtcatgaaac
    91621 cgcaaggtac ctacttgatt tggcttgact tttcagctta tgacctgact gatgaaacat
    91681 tgcaagagtt gttgagaaat gaagccaagg ttatcctcaa ccgtggtttg gattttggag
    91741 aggaaggaag tctccatgcc cgcatcaata tagctatgcc caaatctctg ttgcaagaag
    91801 tctgtcagcg gattgtggct acttttgcca aacgttaaaa atccagcctt ctaggagaaa
    91861 agtcttccta gaaggctatt ttcataggcg aaaatatggt ataataaaaa gataaggtaa
    91921 aggtgaaaat atggctaaat tgattccggg gaaaattcgt atcgaaggtg ttgcccttta
    91981 tgaaactggt aaggttgata tcatcaagga aaagaacaat cggctctacg ctcgcgttgc
    92041 agaagaagaa ctgcgctata gtttagagga tgatttggtt ttttgtgcct gtgatttttt
    92101 tcaaaagagg ggttactgtg tgcatttggc agcgctagag cattttctga aaaatgatga
    92161 gcgtggtcag gaaatcttgt ggagtctgga agaaggtcat gaagaaaaag aggctgttga
    92221 aaccaaggtg accttgggtg gcaagttttt ggatcgaatt ttatctccaa aatcagaatg
    92281 cgcctatgag ttatcagctg tgggtcaggt ggaagcagga accaatcata tcttgtggac
    92341 tctgagaatc ggccaaatca atagccaaaa atactatgtc attcgggata ttccactttt
    92401 tttaaggatt gtcgagcaga gaaagtcgta tatgattggc aagatttatg aggagtctct
    92461 ttcttgggaa gcctttgatg atgccagcca agaacttttg actttcttgc acggactaac
    92521 ggaggaaggg ctggtttcag acctcttttt ccaaaaccaa ggtcggcacc tctttttccc
    92581 tctgaccttt tttgagcagg gtgtgaattt actgatggcc ttgccccatt ttcaatttga
    92641 ccatcaagtg gatagctacc aaaccctgct ttttcaggat atgcatgctg atgccaatct
    92701 atttgccttt acagtaacag aatactcgga ctattttgaa atggaaatca gtgagagtcc
    92761 tagggtcaat gtcttttatc agggagcagt acttttccat aaaggtcagg tttatttttt
    92821 aacagaccag cagatgcgtc ttctcaagga aattaaagcg ttacctgtgg gtcaacaagg
    92881 aaagaaatac ctgcaatttg atagcagtga tcgagacaaa ttggcctcct gtctgactct
    92941 ttttatccag atgggcaccg tttcagctcc agaacgtcta caaatcaaaa cttttgcgcc
    93001 ctctttttac tttgacaggg aagaagataa tcggattcgt ttagaaattc agtttgatta
    93061 tggaaataga caggtatcta gccgacaaga gctagaagaa ttaccatttt caagtgacgc
    93121 ggacttagaa gaaagaattt tccaagtctg tttggctgcg ggctttgaag ccgattttca
    93181 atcttggcgt caggccttaa aagcggagtc tgtctatcat ttttttcatg atatcattcc
    93241 agtctttgaa aaactcgggc atgttgacct atcagataaa ctagaagagc tttatagcct
    93301 agcgagtcct caggtgcaga ttgcctccaa gggaggtctc ttggaaatcc agtttgattt
    93361 tcaagatatt gcccaggagg aaatcgacca agccatgcag gccttggttg ccaatcagga
    93421 tttttatatt gattcgtcta atcaagttta ctttttcgat gaagaaacca agaaaattcg
    93481 ccaaaatcta caggaactgg ggcaatttga attaaaagat gggaccttgc aggctcggaa
    93541 atccttggcc tacagtttag ctcatctctt tgaagggcga gaccgtgttt ctttttcaca
    93601 agaattccag aatctggccc aggatttgac acatccagag gactttcctc gacaggcaac
    93661 tcaggttcag gctgacttgc gagattatca ggaaaaggga attggctggt tgcagatgct
    93721 ccatcattat ggttttggtg ggattttggc tgatgatatg ggacttggga aaacccttca
    93781 gaccattgct tttttgacta gtcaagtgac aaaagaaagt cgggttttga ttctcgctcc
    93841 gtcaggtttg atttacaact gggcagatga gtttcagaaa tttgccccac agttggatgt
    93901 ggctgttgtt catggtttga aagcaagtcg tgaggagatt cttgccgaga gccatcaaat
    93961 ctatgtgact agctatgcca ccttccgtca ggacagtgag ttttatcagg ggatggcctt
    94021 tgacttcctt ttcttagatg aggctcaggt catgaaaaat gcccagacca agattgccca
    94081 gaccttgaga caatttgtgg tgccgtcggt ctttgccttg tcaggaactc cgattgaaaa
    94141 ccatctgggt gagttgtggt ctattttcca aatcgtcatg cccggacttt tgccaagcaa
    94201 gaaagaattt atgaaattgc cagcagagcg agtggctcag tttatcaagc ctttcgtgat
    94261 gcgacgcaag aaagaagaag ttctgactga attgccagac ttgattgagg tggtttataa
    94321 aaatgaactg gaagaccagc aaaaggctat ttaccttgcc cagttacaac agatgcgaga
    94381 ccatctggct caagtgtcag aacaggaatt tcagcgaagt cgtgtggaaa ttttatctgg
    94441 tttgatgcgc ttgcgtcaaa tatgtgacac tcctgccctg tttatggaag attatcaggg
    94501 agccagcggc aaactagata gtctccgaga tctactggta caggtggcag acggcggaca
    94561 ccgtgtcttg attttctctc agttcaaggg aatgttggaa aaaattgaac aagaactgcc
    94621 agacttgggc ctgacatcct ttaaaattac gggtttaacc ccagccaagg aaagacaaga
    94681 catgaccaag gcctttaacc aaggagaaag agatgccttt ctgatttccc tcaaggctgg
    94741 tggggtcggt ctgaacctga caggtgcaga tacagtgatc ttggttgacc tttggtggaa
    94801 tcctgcggtg gaagcgcaag ccattggccg tgcccatcgg atgggtcagg aagaaacggt
    94861 tgaggtctat cgcttggtga ccaagggaac cattgaagaa aaaattcagg aactccaaga
    94921 acaaaagaaa catctggtgt cacaagtatt ggatggcaca gagtcacgtg gtagtctgac
    94981 cctagcagaa attagagaaa ttttgggaat ttctgaagcc agcacttgaa aaatcaagac
    95041 aatacgctat aatgaagtgt tgaaaggaaa tagaaaatga aacaagaacg atttccattg
    95101 gtgtcagatg acgaggtcat gttgactgaa atgccagtca tgaatctcta tgatgagtct
    95161 gatctgatca gtaatatcaa gggtgagtat cgagataaaa attatttaga atgggctcct
    95221 attactgaag aaaaaccagt aaaaccgatt gaaaagcaag tcgaaaaacc taaaaaggct
    95281 cctttagggg ttaaaaaaga aggaaagagc tatgcggagg tggcgcgtga agaagcgcgt
    95341 gcggacttga aaaagaaacg ctctgctaac tacctaactc aggatttcag ccttgcgaga
    95401 cgtcattctc agcccagtct agttagacag ggcaatcaac cgacaactcc tttccaaaag
    95461 gaaaatcctg gtgaatttgt caaatatagc caaaaattga cccagtctca ttatatcttg
    95521 gcggaagaag ttcattctat ccctaccaag aatgaagaag tgtcagcacc tgctccaaag
    95581 aaaaacaatt atgattttct aaagaagagc caaatctaca ataaaaaaag taaacaaaca
    95641 gaacaagaac gtcgggttgc ccaagagttg aatctgacca gaatgacaga ataggggaga
    95701 aaacatgtca aagacatatc attttatcgg aattaaggga tcagggatga gtgccttggc
    95761 cttgatgttg caccagatgg ggcacaaggt tcagggatca gatgttgaaa agtactactt
    95821 tacccaacgc ggtcttgagc aggcaggaat taccattctt ccttttgatg aaaagaatct
    95881 agacggtgat atggaaatta tcgctggaaa tgcctttcgt ccagataaca acgtcgaaat
    95941 tgcctatgcg gaccaaaatg gtatcagcta caaacgttac catgagtttc taggtagctt
    96001 tatgcgtgac tttgttagca tgggagtagc aggagcacat ggaaaaactt caacgacagg
    96061 tatgttgtct catgtcttgt ctcacattac agataccagc ttcttgattg gagatgggac
    96121 aggtcgtggt tcggctaatg ccaaatattt tgtctttgaa tctgacgaat atgagcgtca
    96181 cttcatgcct taccacccag aatactctat tatcaccaac attgactttg accatccaga
    96241 ttatttcaca agtctcgagg atgttttcaa tgcctttaac gactatgcca aacaaattac
    96301 caagggtctt tttgtctatg gtgaagatgc tgaattgcgt aagattacgt ctgatgcacc
    96361 aatttattat tatggttttg aagctgaagg caatgacttt gtagctagtg atcttcttcg
    96421 ttcaacaact ggttcaacct tcaccgttca tttccgtgga caaaacttgg ggcaattcca
    96481 cattccaacc tttggtcgtc acaatatcat gaatgcgaca gccgttattg gtcttcttta
    96541 cacagcagga tttgatttga acttggtgcg tgagcacttg aaaacatttg ccggtgttaa
    96601 acgtcgtttc actgagaaaa ttgtcaatga tacagtgatt attgatgact ttgcccatca
    96661 tccaacagaa attattgcga ccttggatgc ggctcgtcag aaatacccaa gcaaggaaat
    96721 tgtagcagtc tttcaaccgc atacctttac aagaaccatt gccctgttgg acgactttgc
    96781 ccatgcttta aaccaagcag atgctgttta tctagcgcaa atttatggct cggctcgtga
    96841 agtagatcat ggtgacgtta aggtagaaga cctagccaat aaaatcaaca aaaaacacca
    96901 agtgattact gttgaaaatg tttctccact cctagaccat gacaatgctg tttacgtctt
    96961 tatgggagca ggagacatcc aaacctatga atactcattt gagcgtctct tgtctaactt
    97021 gacaagcaat gttcaatagg atgttcccat ggaaattcca attaagatca ttcaggcaag
    97081 caagtttgat ttgcctgaga taggggcact tcagacctcg tcttttccag ctgaaaagca
    97141 gcaactttcc catattttag aagaaagtat ccgtaagtgt gcggatacct ttcttctagc
    97201 tagggatgaa aatcaacttt taggctatat tttatcaagt ccccagtcag acaatccgca
    97261 atgtctaaaa gtacattctt tagtcatcga gtctgaccat cagagacagg gcctgggaac
    97321 acttcttctt gcagccttga aagaggtggc agttgagctg gattacaaag ggattcgttt
    97381 ggagagtcct gatgagctgc tttcctattt tgaaatgaac ggttttgttg atgaagaaga
    97441 aattttgctc tatgcaacta gccagggcta tagtatgatt tggtttaatc ccttttatct
    97501 ggaggaacaa tgaaaatcag acaagcaaga ttagaagatt tggatcggat tgttgaactt
    97561 gaatttgaaa atttttcggt cgaagaagcc attcctcctt ctgtctttga agcacatttg
    97621 agagaaattc agacctcttt tctggttgct gaaaaagaag gaagaatcat gggttatatc
    97681 gaaggaccag ttggcctgca ccgccatctg caagaccagt cttttacaga agaaataaaa
    97741 gactatagtc atgagcctgg tggttatatc tctgtgacct gtctgtctat tgccaaggag
    97801 gcacagggac tcggactggg tcagaaattg ctgacagcct tgaaagaagt tgctcttgaa
    97861 gatgagagag atggcattaa tctaacctgt catgactatc tcatcgccta ttatgaaaaa
    97921 catggatttg tcaacgaagg ccagtcccag tcaacctttg caggggaaac atggtatgat
    97981 atggtctggg aaatgaaaaa ataagttagg aaaagtatca tagattgctt tttttggact
    98041 tttaagatat aatattatgg attatcaaca aggaggaaaa acttttgagt gaaaagtcaa
    98101 gagaagaaga gaaattaagc tttaaagagc agattctgag agatttagaa aaagtaaaag
    98161 gctatgatga agttctgaaa gaagatgagg cagtagttcg cactcctgca aatgaacctt
    98221 cagctgaaga actcatggct gattccttgt caacggtaga ggagattatg agaaaagctc
    98281 ctaccgtgcc tactcaccca agtcaaggtg taccagcttc tccagcagat gagattcaaa
    98341 gagaaactcc tggtgttcca agtcatccaa gtcaagatgt accttcttct ccagcggaag
    98401 aaagtggatc aagaccaggt ccaggtcctg ttagacctaa gaaacttgaa agagaataca
    98461 atgaaacccc aacaagggta gctgtttcct atacgacggc agagaaaaaa gcagaacaag
    98521 caggtccaga aacacctacg cctgctacag aaacagtgga tatcatcaga gatacatcac
    98581 gtcgtagccg tagagaagga gcaaaacccg ttaagcctaa gaaagagaag aagtcacatg
    98641 tgaaagcttt tgtgatttca ttccttgtat tccttgcctt gctctcagca ggtggttact
    98701 ttggttacca gtacgtgcta gattccttat tacctatcga tgctaattct aagaaatatg
    98761 tgacggttgg aattccagaa ggttcaaacg ttcaagaaat cggtacgacg cttgaaaaag
    98821 ctggtttggt aaagcatggt ctgattttta gtttttatgc caagtataaa aattataccg
    98881 acttgaaagc aggttactac aatttgcaaa agagtatgag tacagaagac ttactcaaag
    98941 agttgcaaaa aggtggaaca gatgaaccgc aagaacctgt acttgcgact ttgacaattc
    99001 cagaaggtta taccttggat cagattgctc aaactgtggg tcaattgcaa ggtgacttca
    99061 aagagtcttt gacagcggag gctttcttgg ctaaagttca agatgagacg tttatcagtc
    99121 aagcagtagc gaaatatcct actttactgg aaagtttgcc tgtaaaagac agcggtgcgc
    99181 gttatcgttt ggaaggatac cttttcccag ctacatactc tatcaaggaa agcacaacta
    99241 ttgagagctt gattgatgag atgttagctg ctatggataa gaacctatct ccttactata
    99301 gtactatcaa atctaaaaac ttgactgtca atgagttgtt gaccattgct tccttggtcg
    99361 aaaaagaagg tgccaagaca gaagatcgta agctcattgc aggtgtattc tacaatcgtt
    99421 tgaatcgtga tatgccactt caaagtaata ttgcaatctt gtatgcccaa ggaaaactgg
    99481 ggcaaaatat cagtctagct gaggatgttg cgattgatac caacattgat tcaccttata
    99541 atgtttataa aaatgtaggt ctcatgcctg gtccagtcga tagtccaagt ctggatgcga
    99601 ttgagtcaag catcaatcaa actaagagcg ataacctcta ctttgtagca gatgtcacag
    99661 aaggcaaggt ctactatgct aacaatcaag aagaccacga ccgcaatgtc gctgaacatg
    99721 tcaacagcaa attaaactaa acaaactaaa attatgtgat acttcacata attttcttta
    99781 gaaaatatta tcagaagaaa gttgagaaaa atggcagaaa aaacatatcc tatgaccctt
    99841 gaggaaaagg aaaaacttga aaaagaatta gaagaattga aattggttcg tcgaccagaa
    99901 gtggtagaac gcattaagat tgcccgttca tacggtgacc tttcagaaaa cagtgagtac
    99961 gaagcagcta aggatgaaca agcctttgtc gaaggacaaa tctctagctt agaaacaaaa
   100021 atccgctatg ctgaaatcgt caatagcgac gcagttgccc aggacgaagt agcgattggt
   100081 aaaacagtca ccatccaaga aattggtgag gacgaagaag aagtttatat tatcgtaggt
   100141 tcagctggtg cggatgcctt tgcaggtaag gtttcaaatg aaagcccaat tgggcaggcc
   100201 ttgattggca agaaaacagg tgatacagca accattgaaa cgcctgttgg tagctatgat
   100261 gtaaaaatct tgaaggttga aaaaacagcc taaaaacaga aaaaggagtg gggaggcgat
   100321 gtgcttcact cactcctttt tccattttgc tactcttcga aaatctcttc aaaccacgtc
   100381 agcgtcgcct tgccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa
   100441 cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt tattgagtat
   100501 tagatgtata gtgcattgaa gttaaaatag tacactttga tttctaagac attgttagaa
   100561 attagattaa attccttaat cgatttgcgc atgttttatt tcatttcact atactttaga
   100621 ttggaaaata aggaatcaca taaatcgcaa gaaataggga atctgattcg tgtttataac
   100681 cgttcaaaaa gagaagaggc tgaaagtgag ccacttaatc tttatgtcga agatgaaaag
   100741 ggcaatctcc tggcaggttt gatagcagag acttttggaa attggctaga aatcgagtat
   100801 ttgtttgtaa aagaggaact gcgagggcaa ggaatcggtt caaaactatt gcaacaggca
   100861 gaaagtgaag ctaagaatcg aaattgttgt tttgcctttg tcaatactta ccagttccag
   100921 gcaccggact tttatcagaa acatggctac aaggaagttt tttctttgca agactatctc
   100981 tacattaggc aaagatatta ttaccaaaag aatctgtaag gtgagtatgg aggtataata
   101041 caaagagagg ctcgcacata agtatggagg tggactgatg tatatgagta actattgata
   101101 aataccagtt ataacctaga aattgtgtct ttctagacga tattgaggac aatataatcg
   101161 tagccccaaa attaggaatc aagacttatc aggttaagaa aagaagtgat gttgttgata
   101221 ttttaaacaa tttatttaaa ctaaaaactc tctatctatt aatccgagat tcccctctcg
   101281 gattttgtgt tgctttcatt aaatttacag gtaagacttg ctagcttcag taaatataca
   101341 caagtttttc agaatagagt gaaatccaaa agaaaatgga aataatgaaa gctcttgtag
   101401 gcataagaaa acacctctgt gttatacttg ttgttcaacc acaaacacaa gaaaggcaca
   101461 gaaatgcaag acaattatac tacaaaaggt aaacatttga caatcgatag ccgtcgctta
   101521 atcgaaagat ggaaaaaaga aggaaaatca aatagagaaa ttgcctctct acttggaaaa
   101581 gctcctcaaa ctatccacac taaaatcaag cgtaggacag tccgaaaatg tcttggaaaa
   101641 gggcgcttca aagaggttta ttctgccgac tatgctcaac agtcttatga aaataatcgc
   101701 aagcactcgg tcaagagatc aagcgtgacc aaggaactaa aggaaaagat tctccactat
   101761 cataaccaaa aatttttgcc tgaaatgatg gttatggcta aaggggttaa cgtgggaatt
   101821 tcaaccattt actattggat tcatcatgga aaattggggt aaagcaagca ggatctgctt
   101881 taccctagaa aaggaaaagc gcttaagaaa caggccagca ccaactttaa acctgctggt
   101941 caatccatcg aacagcggcc tgaagctatc aattttcgct tggagaatgg gcattatgag
   102001 attgatacgg ttctacttac gagagcgaaa aactactgct tgcttgtctt gacggatcga
   102061 aaaagtagac atcagatcat ccgattgatt ccaaataaaa gtgctgaggt ggtcaatcag
   102121 gctctaaaac tcatcttaaa acaacacaag attctttcca tcacggcaga taatggaacg
   102181 gaattcaatc gcttgtctaa tgtattttct gaggagcaca tttattatgc acatccctat
   102241 gcctcttggg aaaggggaac taatgagaat cacaacaggc tcattcgtag atggttacct
   102301 aagggaacca agaaaatgac tcccaaagaa gtcgcattca tcgaaaagtg gattaacaac
   102361 tatcctaaaa aatgcttgga ctacaagtca cccagagaag acttctggat ggctaacttg
   102421 aacttgaaat ttagcaaaat ggaaataatt tttattaaac gcttccaata gcggttaaaa
   102481 gttgacaaat ttaaatttta ggactacact aagtaagtaa attttatttt aaaggagaat
   102541 ttgttatgaa tttaacattt ttaggcttat gtattgcctg tatgggcgta tctgtcggtg
   102601 aaggtttatt gatgaatgga ctgtttaaat cagtagcacg ccaaccagat atgctttctg
   102661 agtttcgtag tttgatgttt ttaggtgttg cctttattga aggaactttc tttgtaactc
   102721 ttgtcttctc atttattatc aaataaatac atggaacgag aagaaaaggg aggattttag
   102781 atggaagaaa gtattaatcc aatcatctct attggtcctg ttatcttcaa tctgactatg
   102841 ttagccatga ctttgttgat tgtgggagtt atttttgtct ttatttattg ggcaagccgc
   102901 aatatgacct tgaaacccaa aggaaagcaa aatgtacttg agtatgtcta tgactttgtt
   102961 attggattta cagaacctaa cattggttcg cgctacatga aagattactc actctttttc
   103021 ctttgtttat tccttttcat ggtgattgcc aataaccttg gcttaatgac aaagcttcaa
   103081 acgatcgatg ggactaactg gtggagttcg ccaaccgcta atttacagta tgacttaacc
   103141 ttatcttttc ttgtcatttt gttgacacat atagaaagcg ttcgtcgtcg tggatttaaa
   103201 aaaagtataa aatcttttat gagtcctgtt tttgtcatac cgatgaatat cttggaagaa
   103261 tttacaaact tcttatcttt ggctttgcgg atttttggga atatctttgc aggagaggtc
   103321 atgacgagtt tgttacttct tctttcccac caaactattt attggtatcc agtagccttt
   103381 ggagctaatt tggcttggac tgcattttct gtctttattt cctgcatcca agcttatgtt
   103441 tttactcttt tgacatctgt gtatttaggg aataagatta atattgaaga ggaatagaaa
   103501 ggagtaactg atgcacgtaa cagtaggtga attaattggt aattttattt taatcactgg
   103561 ctcttttatt cttttgctag tcttgattaa aaaatttgca tggtctaata ttacaggcat
   103621 tttcgaagaa agagctgaaa aaattgcttc agatattgac agagctgaag aagcccgtca
   103681 aaaagcagaa gtattggctc aaaaacgcga agatgaattg gctggtagcc gtaaagaagc
   103741 taagacaatc attgaaaatg caaaggaaac agctgagcaa agtaaggcta atatcttagc
   103801 agatgctaaa ctagaagcag gacacttaaa agaaaaagcc aatcaagaaa ttgctcaaaa
   103861 taaagtagaa gctttacaga gtgttaaggg tgaggtcgca gatttgacca tcagcttagc
   103921 tggtaaaatc atctcacaaa accttgacag tcatgcccat aaagcactca ttgatcagta
   103981 tatcgatcag ctaggagaag cttaatggac aagaaaacag taaaggtaat tgaaaaatac
   104041 agcatgcctt ttgtccaatt ggtacttgaa aaaggagaag aagaccgtat cttttcagac
   104101 ttgactcaaa tcaagcaagt tgttgaaaaa acaggtctgc cttctttttt aaaacaagtg
   104161 gcagtagacg agtcggataa ggaaaaaaca attgcttttt tccaagattc tgtgtcgcct
   104221 ttattacaaa actttatcca ggttctggcc tacaatcaca gagcaaatct tttttatgat
   104281 gtgcttgtag attgcttgaa ccgacttgaa aaagaaacaa atcgatttga agtgacgatt
   104341 acgtctgctc atcctctaac tgatgaacag aagactcgtt tgctcccttt gattgagaaa
   104401 aaaatgtctc tgaaagtaag gagtgtaaaa gaacaaatcg atgaaagtct cattggtggt
   104461 tttgtcattt ttgccaatca caagacaatt gatgtgagta ttaaacaaca acttaaagtt
   104521 gttaaagaaa atttgaaata gaaagtggtg ttcttttggc aattaacgca caagaaatca
   104581 gcgctttaat taagcaacaa attgaaaatt tcaaacccaa ttttgatgtg actgaaacag
   104641 gtgttgtaac ctatatcggg gacggtatcg cgcgtgctca tggccttgaa aatgtcatga
   104701 gtggagagtt gttgaatttt gaaaacggct cttatggtat ggctcaaaac ttggagtcaa
   104761 cagacgttgg tattatcatc ctaggtgact ttacagatat ccgtgaaggc gatacaatcc
   104821 gccgtacagg gaaaatcatg gaagtccctg taggtgaaag tctgattggt cgtgttgtgg
   104881 atccgcttgg tcgtccagtt gacggtcttg gagaaatcca cactgataaa actcgtccag
   104941 tagaagcacc agctcctggt gttatgcaac gtaagtctgt ttcagaacca ttgcaaactg
   105001 gtttgaaagc tattgacgcc cttgtaccga ttggtcgtgg tcaacgtgag ttgattatcg
   105061 gtgaccgtca gacagggaaa acaaccattg cgattgatac aatcttgaac caaaaagatc
   105121 aagatatgat ctgtatctac gtcgcgattg gacaaaaaga atcaacagtt cgtacgcaag
   105181 tagaaacact tcgtcagtac ggtgccttgg actacacaat cgttgtgaca gcctctgctt
   105241 cacaaccatc tccattgctc ttcctagctc cttatactgg ggttgctatg gcggaagaat
   105301 ttatgtatca aggtaagcat gttttgattg tatacgatga tctatcaaaa caagcggtag
   105361 cttatcgtga actatcgctc ttgcttcgtc gtcctccagg tcgtgaagcc ttcccagggg
   105421 atgttttcta tctccacagc cgtttgcttg agcgctcagc taaagtttct gatgaacttg
   105481 gtggtggatc aattacagcc ctaccattta tcgagacaca agcaggagat atctcagcct
   105541 atatcgcaac caacgtgatt tctatcactg atggacaaat cttccttggc gatggcctct
   105601 tcaatgcagg tattcgtcca gccatcgatg cgggttcatc tgtatctcgt gtaggtggtt
   105661 ctgcacaaat caaagccatg aagaaggttg ctggtacact tcgtatcgac cttgcttcat
   105721 accgtgagtt ggaagccttt actaagtttg gttctgactt ggacgcagca acacaggcta
   105781 agttgaaccg tggacgtcgt accgttgagg tcttgaaaca acctgttcac aaaccattac
   105841 ctgttgagaa acaagtaacc attctttatg ctttgacaca tggtttcttg gatactgttc
   105901 cagtagatga tattgttcgt ttcgaggaag agttccatgc cttctttgat gctcaacatc
   105961 cagagatttt ggaaaccatt cgtgatacaa aagacttgcc agaagaagca gtcttggatg
   106021 ctgcgattac agagtttctc aatcaatcta gcttccaata agaatagagg tgtcagatgg
   106081 cagtgtctct aaatgatatt aaaacaaaaa tcgcctcaac aaaaaatacg agtcaaatca
   106141 ctaatgccat gcaaatggta tcggctgcta agttaggtcg ctctgaagaa gctgctcgca
   106201 acttccaagt ttacgctcag aaagtgcgta aacttttgac agatatcctt catggtaatg
   106261 gagctggtgc ttcaactaat ccgatgttga ttagccgttc tgtgaagaag acaggctata
   106321 tcgttatcac ttcagaccgc ggtttggttg gaggttataa ttcctctatt ttgaaagctg
   106381 ttatggagtt gaaagaagaa taccacccag acggtaaagg ttttgaaatg atctgtatcg
   106441 gtgggatggg agctgatttc tttaaggctc gcggtattca accactttat gaattacgtg
   106501 gcttggcaga ccaacctagc tttgatcaag ttcgtaagat tatttcaaaa actgttgaaa
   106561 tgtaccaaaa tgaactcttt gatgagcttt atgtttgcta caaccaccat gtcaatacgc
   106621 taaccagtca aatgcgtgtg gaacaaatgc ttccgattgt tgacttggat ccaaatgaag
   106681 cggatgaaga gtacagcttg acttttgaat tggaaaccag ccgagaagaa attctggagc
   106741 agttgttgcc tcagtttgca gaaagtatga tttacggtgc cattatcgat gccaagacag
   106801 ctgagaatgc tgcgggtatg acagccatgc aaacagcgac agataatgct aagaaagtca
   106861 tcaatgattt gacaattcag tataaccgtg ccagacaggc ggcgattaca caagaaatta
   106921 cagaaatcgt agcaggtgct agtgccttag aataggccct agtccagctc gtatgaaaat
   106981 gaacttagga cctagttgag ctaggaaccg acagtatctt atatagaata ggagaaggag
   107041 atgagttcag gtaaaattgc tcaggttatc ggtcccgttg tagacgtttt gtttgcagca
   107101 ggggaaaaac ttcctgagat taacaatgca cttgtcgtct acaaaaatga cgaaagaaaa
   107161 acaaaaatcg tccttgaagt agccttggag ttaggagatg gtatggttcg tactatcgcc
   107221 atggaatcaa cagatgggtt gactcgtgga atggaagtat tggacacagg tcgtccaatc
   107281 tctgtaccag taggtaaaga aactttggga cgtgtcttca acgttttggg agataccatt
   107341 gatttggaag ctccttttac agaagacgca gagcgtcagc caattcataa aaaagctcca
   107401 acttttgatg agttgtctac ctcttctgaa atccttgaaa cagggatcaa ggttattgac
   107461 cttcttgccc cttaccttaa aggtggtaaa gttggacttt tcggtggtgc cggagttggt
   107521 aaaaccgtct taatccaaga attgattcac aacattgccc aagagcacgg tggtatttca
   107581 gtatttgctg gtgttgggga acgtactcgt gaggggaatg acctttactg ggaaatgaaa
   107641 gaatcaggcg ttatcgagaa aacagccatg gtctttggtc agatgaatga gccaccagga
   107701 gcacgtatgc gtgttgccct tactggtttg acaatcgctg aatacttccg tgatgtggaa
   107761 ggccaagacg tgcttctctt tatcgataat atcttccgtt tcactcaggc tggttcagaa
   107821 gtatctgccc ttttgggtcg tatgccatca gccgttggtt accaaccaac acttgctacg
   107881 gaaatgggtc aattgcaaga acgtatcaca tcaaccaaga agggttctgt aacctctatc
   107941 caggctatct atgtgccagc ggatgactat actgacccag cgccagcaac agccttcgct
   108001 cacttggatt caacaacaaa cttggaacgt aagttggtac aattgggtat ctacccagcc
   108061 gttgacccac ttgcttcaag ctcacgtgcc ttggcacctg aaatcgttgg agaagagcac
   108121 tatgcagttg ctgctgaagt aaaacgtgtc cttcaacgtt accatgaatt gcaagatatc
   108181 attgctatcc ttggtatgga tgagctttct gatgaagaaa agaccttggt tgctcgcgcc
   108241 cgtcgtatcc agttcttctt gtcacaaaac ttcaacgttg cggaacaatt tactggtcag
   108301 ccaggttctt atgttccagt tgctgaaact gtacgtggct ttaaggaaat ccttgatggt
   108361 aaatacgacc acttgccaga agatgccttc cgtggtgtag gttctatcga agatgtgatt
   108421 gcaaaagctg aaaaaatggg attttaagag gtgatctatg gctcagttaa ctgtccagat
   108481 cgtgacacca gatggtctcg tctatgatca ccatgccagc tatgtatcgg ttcgaactct
   108541 ggatggtgag atggggatct tgccacgaca tgaaaatatg attgcagttt tagcagttga
   108601 tgaagtaaag gtaaaacgta tcgatgataa agatcacgtg aactggattg cagtaaacgg
   108661 tggtgttatt gaaattgcca atgatatgat cacaatcgtc gctgactctg cagaacgtgc
   108721 tcgtgatatc gatatcagtc gtgcagaacg tgccaaactt cgtgcagaac gtgcaattga
   108781 agaagcacaa gacaaacatt tgattgacca agaacgtcgt gctaagattg ctttgcaacg
   108841 tgctattaac cgtattaatg tcggaaatag actataagaa aaaatgaact tgaaaatacc
   108901 aagttcattt tttatggtgt tttaaggagc aaaacggatg cagactgctt cgggaacatg
   108961 gaagtcgttg gagagttctg ctagacgacc attgtcacaa ttacgtttaa agacagttgc
   109021 attgtcagag tcttgatgga caacaatgag aaatttttgg tcgggtgtca aatcaaaatc
   109081 acgtggagtc tgaccatgcg ttggaacgat ttctaataac tctaagctac cgtccgcaag
   109141 gatggtatat actgcgatag aatcatggcc acggttagaa gcgtagaggt atttaccgtc
   109201 tttagagaga tgaatagcag cggttccatt aaagccttcg taagcttccg gtaaagttga
   109261 aatgacctgc atacgttcaa attcgccaac gccatcgtag attaaaactt cgatagtact
   109321 attgagttca caaatgagat aagcgatttt atagtggtta tggaaaatga tatggcgtga
   109381 gcctgctcct ggcttgctgt gataggtata gagcttagat aattttcctt cttgatcgag
   109441 gtcataggtg atgacttggt cagttcccaa gtcgcaggtc actagatagt ggtcaggtgt
   109501 taaatctgta tagtgaacat ggggggaagc ttgattttca tgtggacctt ggccactgtg
   109561 ttgatccata tcactaagta gaagactacc atcttcctgg cgtttataaa caaggacttg
   109621 tcccttgtga tagttggctg cgtaaaccaa atcacgcttt tcatcgacag caacataaca
   109681 gtggggagct ccttcttcaa caacatgatt taacacagtc ccgtcagttt gataggctgc
   109741 aattcccccc ttatcgtctt ggctaccaac agtgtataaa tgttggtgct ggtcaaaggc
   109801 aaggtaggtt ggacttggct cagctgcaaa aagttctaga tttgaaagct gaccagtttc
   109861 tgtatcaaag tctgccttgt aaatcccttg agaagtacga cgtgtataag ttccaaaata
   109921 aacagtttct ttcattacta tacctctgtg taaagataag actattatat cacaaaaaca
   109981 agcaaattaa agacattcaa ttagatgtaa gcactttaaa aaagagttat tttgtttcaa
   110041 aaatggtata atgagagaac aatagaaagg aagtatttat ggagcaaaaa gagaaacatt
   110101 ttagcctatc ttggtttttc aagtggtttt tagataacaa ggcaattacg gtatttttag
   110161 taaccttatt attgggattg aatcttttta ttttaagtaa gattagtttt ctattttcac
   110221 ctgttttaga ctttttagca gttgtgatgt tgccagtcat tttgtctggt ttgttatatt
   110281 atttgttgaa tcctattgtt gattggatgg agaagcataa ggttaatcgt gttatagcta
   110341 tcactattgt ctttgttatc atcgctctct ttatcatttg gggcttggca gtcgccattc
   110401 caaatctgca acgtcaggtt ttgacctttg caagaaacgt tcctgtttac ttagaagata
   110461 tagataggat tgttaatgga ttggtagccc agcatctgcc agatgatttc agacctcaat
   110521 tagagcaagt tttgaccaat ttttctagcc aggctacagt tttggcaagt aaggtttcat
   110581 ctcaggcagt caactgggtg agtgccttta ttagcggggc ttctcaagtg attgttgcct
   110641 tgattatcgt tcctttcatg ctcttttatc tcttgcgtga tgggaaaggc ttgcgtaact
   110701 atttgaccca attcattcca agaaaattga aggaacctgt tggacaagtt ctatcagatg
   110761 tgaatcaaca gttgtccaac tatgttcgag ggcaagtgac agtggctatt attgtagcag
   110821 taatgtttat catcttcttc aagattattg gtctacgcta tgcggttacg ctgggggtta
   110881 ctgctggtat tttaaatctg gtcccttatc ttggtagctt tctagccatg cttcctgccc
   110941 tagtattggg tttgattgct ggtccagtca tgcttttgaa agtagtgatt gtctttattg
   111001 tagaacaaac tattgaaggc cgttttgtct ctccattgat tttgggaagt caattaaaca
   111061 tccaccctat taatgttctc tttgttttgt taacttcagg atctatgttt ggtatctggg
   111121 gagttttact tggtattcca gtttatgcct ctgctaaggt tgtcatttca gccattttcg
   111181 aatggtataa ggtagtcagt ggtctatatg aattagaggg tgaggaagtc aagagtgaac
   111241 aatagtcaac agatgttaca ggctttggag gagcaagatt taactaaggc tgagcattat
   111301 ttcgccaaag ctttagaaaa tgattcaagt gatcttctgt atgagttggc aacttatctt
   111361 gaagggattg gtttctatcc tcaggccaag gaaatttacc tgaaaattgt agaggatttt
   111421 ccagaggttc atcttaatct agctgcaatt gctagcgagg atggtcaaat agaagaagcc
   111481 tttacctatc ttgaggaaat ccaagctgac agtgactggt atgtctcgtc tttggttttg
   111541 aaggcagacc tttaccagct ggaaggtttg acagatgtgg cacgtgagaa attattggag
   111601 gccttgacct actcagagga ttctctcttg atattgggtt tggcagagtt ggatagtgag
   111661 ttggaaaatt accaagcggc tattcaagcc tatgcccagt tagataatcg ctcgatttat
   111721 gagcaaacgg gcatttccac ctatcaacga attggctttg cctatgctca gttagggaaa
   111781 tttgaaacgg ctactgagtt tttagaaaaa gccctggagt tagaatacga tgacttaaca
   111841 gcttttgagt tggccagtct ttattttgat caagaagaat atcaaaaagc caccctctac
   111901 tttaagcagc ttgataccat ttctcctgac tttgaaggct atgagtatgg gtacagtcag
   111961 gctttacata aggaacatca agttcaagaa gccctgcgta tcgctaagca aggattagag
   112021 aaaaatccct ttgaaactcg cctcttgcta gctgcttcac aattttctta tgaattgcat
   112081 gatgctagtg gtgcagaaaa ttatctcctt actgcaaaag aagacgctga ggatacagaa
   112141 gaaatcttgc ttcgtttagc cactatttat ctggagcagg agcgttatga ggatattcta
   112201 gacttgcaga gtgaggagcc agaaaatctt ttgaccaagt ggatgattgc tcgttcttat
   112261 caagaaatgg acgatttgga tactgcttat gagcattatc aagagttgac aggagatttg
   112321 aaggacaatc cagaatttct ggaacactat atctatctct tgcgtgaatt gggacatttt
   112381 gaagaagcaa aagtccatgc tcacacttac ttaaaactgg ttccagatga tgtgcaaatg
   112441 caagaactgt ttgagagatt gtaagaatgt ttaaacatat agaactgtag tttatctctt
   112501 ttgatagctg cggtttttat ttgtatatgg tagaatcttt ttacaaaaat acttggtaat
   112561 cttgtttatt catgctataa taggaacaat tacttttagg aggtgcagta tgtcttattt
   112621 atttgagata ttaccgagtt tactgaatgg tgcgagcacg actgtacagg tctttgcact
   112681 ggtcttgcta ttttcgattc cgttgggcgt tttgattgcc tttgccttgc aagtccattg
   112741 gaagcccctc cattatctga ttaacattta catctgggtt atgcgaggaa cccccttact
   112801 cttgcaactg atttttatct attatgtgct cccaagtatt gggattcgtt tagaccgcct
   112861 tcctgcagct attattgcct ttgttctcaa ctatgcagct tactttgcag aaattttccg
   112921 tgggggaatt gacactattc caagaggaca gtatgaggct gccaaggtct tgaagtttag
   112981 cccttttgac agagtgcgct atattatctt gccccaagtg accaagatcg ttcttcctag
   113041 tgtctttaat gaagttatga gtttggtcaa ggatacttct ttggtctatg ctctcggaat
   113101 ttcagacctt atcttggcta gtcgaacagc tgctaaccgc gatgctagtc tggttcctat
   113161 gttcttggca ggagccattt acttgatttt aattgggatt gtgacaatta tttccaaaaa
   113221 agttgagaag aagtatagtt attatagata gggggcagct atgttagaat tacgaaatat
   113281 caataaagtc tttggagaca aacaaatcct gtctgatttc agtctaagta ttcctgaaaa
   113341 gcaaatcctg gctatcgttg gaccttctgg tggaggtaag acaactcttt tacgtatgct
   113401 tgcaggtctt gaaaccattg attcagggca aatcttttat aatggacaac ctttagagct
   113461 agatgaattg cagaagcgca acctactggg atttgtcttc caagattttc aactatttcc
   113521 tcatctatca gttctggaaa atttgacttt atcgcctgtg aagaccatgg gaatgaagca
   113581 ggaagaggct gagaagaagg cgagtgaact cttggaacag ttaggactag gaggacacgc
   113641 agaggcctat cctttctcac tatctggtgg gcaaaagcag cgggtggctt tggcgcgtgc
   113701 tatgatgatt gacccagaaa tcattggcta cgatgaacca acttctgccc tggatccaga
   113761 attacgtttg gaagtggaga agctaatctt gcaaaatagg gaacttggga tgacccagat
   113821 tgtggttacc catgatttgc agtttgctga aaatatcgca gatgtattat tgaaagtaga
   113881 acctaaatag gaggaaaaat ggatgaaaaa atggatgctt gtattagtca gtctgatgac
   113941 tgctttgttc ttagtagctt gtgggaaaaa ttctagcgaa actagtggag ataattggtc
   114001 aaagtaccag tctaacaagt ctattactat tggatttgat agtacttttg ttccaatggg
   114061 atttgctcag aaagatggtt cttatgcagg atttgatatt gatttagcta cagctgtttt
   114121 tgaaaaatac ggaatcacgg taaattggca accgattgat tgggatttga aagaagctga
   114181 attgacaaaa ggaacgattg atctgatttg gaatggctat tccgctacag acgaacgccg
   114241 tgaaaaggtg gctttcagta actcatatat gaagaatgag caggtattgg ttacgaagaa
   114301 atcatctggt atcacgactg caaaggatat gactggaaag acattaggag ctcaagctgg
   114361 ttcatctggt tatgcggact ttgaagcaaa tccagaactt ttgaagaata ttgtcgctaa
   114421 taaggaagcg aatcaatacc aaacctttaa tgaagccttg attgatttga aaaacgatcg
   114481 aattgatggt ctattgattg accgtgtcta tgcaaactat tatttagaag cagaaggtgt
   114541 tttaaacgat tataatgtct ttacagttgg actagaaaca gaagcttttg cggttggagc
   114601 ccgtaaggaa gatacaacct tggttaagaa gataaatgaa gctttttcta gtctttacaa
   114661 ggacggcaag ttccaagaaa tcagccaaaa atggtttgga gaagatgtag caaccaaaga
   114721 agtaaaagaa ggacagtaag ataaaatagt ggctgaaact gcgttttgat tagcaaaacg
   114781 tagttttttt gtaatctagg aaaacgataa tagcgattga atctggataa tt
//
LOCUS       DAVLZG010000002        79884 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLZG010000002 DAVLZG010000000
VERSION     DAVLZG010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.002"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            169..1650
                     /locus_tag="VYO72_000124"
     CDS             169..1650
                     /locus_tag="VYO72_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1706579.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2012..3013
                     /locus_tag="VYO72_000125"
     CDS             2012..3013
                     /locus_tag="VYO72_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1706580.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3164..4081
                     /locus_tag="VYO72_000126"
     CDS             3164..4081
                     /locus_tag="VYO72_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1706581.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4092..4982
                     /locus_tag="VYO72_000127"
     CDS             4092..4982
                     /locus_tag="VYO72_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1706582.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5011..6627
                     /locus_tag="VYO72_000128"
     CDS             5011..6627
                     /locus_tag="VYO72_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1706583.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISDNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6637..7956
                     /locus_tag="VYO72_000129"
     CDS             6637..7956
                     /locus_tag="VYO72_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1706584.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8166..8238)
                     /locus_tag="VYO72_000130"
     tRNA            complement(8166..8238)
                     /locus_tag="VYO72_000130"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8203..8205),aa:Lys,seq:ctt)
     gene            complement(8503..9774)
                     /locus_tag="VYO72_000131"
     CDS             complement(8503..9774)
                     /locus_tag="VYO72_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1706585.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10044..10244
                     /locus_tag="VYO72_000132"
     CDS             10044..10244
                     /locus_tag="VYO72_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706586.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10448..10627
                     /locus_tag="VYO72_000133"
     CDS             10448..10627
                     /locus_tag="VYO72_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706587.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10764..10943
                     /locus_tag="VYO72_000134"
     CDS             10764..10943
                     /locus_tag="VYO72_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1706588.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10980..11432
                     /locus_tag="VYO72_000135"
     CDS             10980..11432
                     /locus_tag="VYO72_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1706589.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11723..12193
                     /locus_tag="VYO72_000136"
     CDS             11723..12193
                     /locus_tag="VYO72_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1706590.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12249..12791
                     /locus_tag="VYO72_000137"
     CDS             12249..12791
                     /locus_tag="VYO72_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706591.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFEDLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            12841..13005
                     /locus_tag="VYO72_000138"
     CDS             12841..13005
                     /locus_tag="VYO72_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV1706592.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGKSVRENLI"
     gene            13115..14149
                     /locus_tag="VYO72_000139"
     CDS             13115..14149
                     /locus_tag="VYO72_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1706593.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14151..16394
                     /locus_tag="VYO72_000140"
     CDS             14151..16394
                     /locus_tag="VYO72_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV1706594.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            16445..17464
                     /locus_tag="VYO72_000141"
     CDS             16445..17464
                     /locus_tag="VYO72_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1706595.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            17477..18427
                     /locus_tag="VYO72_000142"
     CDS             17477..18427
                     /locus_tag="VYO72_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1706596.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18429..19172
                     /locus_tag="VYO72_000143"
     CDS             18429..19172
                     /locus_tag="VYO72_000143"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1706597.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19183..20979
                     /gene="pepF"
                     /locus_tag="VYO72_000144"
     CDS             19183..20979
                     /gene="pepF"
                     /locus_tag="VYO72_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1706598.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(21039..21311)
                     /locus_tag="VYO72_000145"
                     /pseudo
     CDS             complement(21039..21311)
                     /locus_tag="VYO72_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            21299..21481
                     /locus_tag="VYO72_000146"
                     /pseudo
     CDS             21299..21481
                     /locus_tag="VYO72_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
     gene            complement(21605..21694)
                     /locus_tag="VYO72_000147"
                     /pseudo
     CDS             complement(21605..21694)
                     /locus_tag="VYO72_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21691..22224)
                     /gene="queF"
                     /locus_tag="VYO72_000148"
     CDS             complement(21691..22224)
                     /gene="queF"
                     /locus_tag="VYO72_000148"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1706599.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISINPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(22529..22843)
                     /gene="trxA"
                     /locus_tag="VYO72_000149"
     CDS             complement(22529..22843)
                     /gene="trxA"
                     /locus_tag="VYO72_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1706600.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(22860..23081)
                     /locus_tag="VYO72_000150"
     CDS             complement(22860..23081)
                     /locus_tag="VYO72_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1706601.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(23180..23560)
                     /locus_tag="VYO72_000151"
     CDS             complement(23180..23560)
                     /locus_tag="VYO72_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1706602.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(23703..24656)
                     /locus_tag="VYO72_000152"
     CDS             complement(23703..24656)
                     /locus_tag="VYO72_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1706603.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(24724..25935)
                     /gene="sstT"
                     /locus_tag="VYO72_000153"
                     /pseudo
     CDS             complement(24724..25935)
                     /gene="sstT"
                     /locus_tag="VYO72_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012962425.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            26074..26634
                     /locus_tag="VYO72_000154"
     CDS             26074..26634
                     /locus_tag="VYO72_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEV1706604.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            26691..27599
                     /locus_tag="VYO72_000155"
     CDS             26691..27599
                     /locus_tag="VYO72_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1706605.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            27551..28141
                     /locus_tag="VYO72_000156"
     CDS             27551..28141
                     /locus_tag="VYO72_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1706606.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            28144..29250
                     /gene="yqeH"
                     /locus_tag="VYO72_000157"
     CDS             28144..29250
                     /gene="yqeH"
                     /locus_tag="VYO72_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1706607.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPSLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            29464..29775
                     /gene="yhbY"
                     /locus_tag="VYO72_000158"
     CDS             29464..29775
                     /gene="yhbY"
                     /locus_tag="VYO72_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1706608.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            29827..30456
                     /locus_tag="VYO72_000159"
     CDS             29827..30456
                     /locus_tag="VYO72_000159"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1706609.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVAYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            30456..31049
                     /gene="yqeK"
                     /locus_tag="VYO72_000160"
     CDS             30456..31049
                     /gene="yqeK"
                     /locus_tag="VYO72_000160"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1706610.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            31050..31550
                     /locus_tag="VYO72_000161"
     CDS             31050..31550
                     /locus_tag="VYO72_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1706611.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            31563..31916
                     /gene="rsfS"
                     /locus_tag="VYO72_000162"
     CDS             31563..31916
                     /gene="rsfS"
                     /locus_tag="VYO72_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1706612.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            32019..32765
                     /locus_tag="VYO72_000163"
     CDS             32019..32765
                     /locus_tag="VYO72_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1706613.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            32775..33872
                     /locus_tag="VYO72_000164"
     CDS             32775..33872
                     /locus_tag="VYO72_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1706614.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            34110..34340
                     /locus_tag="VYO72_000165"
     CDS             34110..34340
                     /locus_tag="VYO72_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1706615.1"
                     /translation="MEGVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            34609..36222
                     /locus_tag="VYO72_000166"
     CDS             34609..36222
                     /locus_tag="VYO72_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1706616.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            36352..36978
                     /gene="gmk"
                     /locus_tag="VYO72_000167"
     CDS             36352..36978
                     /gene="gmk"
                     /locus_tag="VYO72_000167"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1706617.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            37003..37317
                     /locus_tag="VYO72_000168"
     CDS             37003..37317
                     /locus_tag="VYO72_000168"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1706618.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            37383..39779
                     /locus_tag="VYO72_000169"
     CDS             37383..39779
                     /locus_tag="VYO72_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1706619.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYRHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQFGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            39792..40727
                     /locus_tag="VYO72_000170"
     CDS             39792..40727
                     /locus_tag="VYO72_000170"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1706620.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            40720..42033
                     /gene="rsmB"
                     /locus_tag="VYO72_000171"
     CDS             40720..42033
                     /gene="rsmB"
                     /locus_tag="VYO72_000171"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1706621.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            42048..42788
                     /locus_tag="VYO72_000172"
     CDS             42048..42788
                     /locus_tag="VYO72_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1706622.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            42785..44764
                     /gene="pknB"
                     /locus_tag="VYO72_000173"
     CDS             42785..44764
                     /gene="pknB"
                     /locus_tag="VYO72_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1706623.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKTPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPIQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            44895..45653
                     /locus_tag="VYO72_000174"
     CDS             44895..45653
                     /locus_tag="VYO72_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1706624.1"
                     /translation="MEESKELNTVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            45655..46104
                     /locus_tag="VYO72_000175"
     CDS             45655..46104
                     /locus_tag="VYO72_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1706625.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            46166..46789
                     /locus_tag="VYO72_000176"
                     /pseudo
     CDS             46166..46789
                     /locus_tag="VYO72_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            46857..47105
                     /locus_tag="VYO72_000177"
     CDS             46857..47105
                     /locus_tag="VYO72_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706626.1"
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            47236..48408
                     /locus_tag="VYO72_000178"
     CDS             47236..48408
                     /locus_tag="VYO72_000178"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1706627.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            48408..49682
                     /locus_tag="VYO72_000179"
     CDS             48408..49682
                     /locus_tag="VYO72_000179"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1706628.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(49717..50682)
                     /locus_tag="VYO72_000180"
     CDS             complement(49717..50682)
                     /locus_tag="VYO72_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1706629.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(50663..52117)
                     /locus_tag="VYO72_000181"
     CDS             complement(50663..52117)
                     /locus_tag="VYO72_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1706630.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            52494..54377
                     /locus_tag="VYO72_000182"
     CDS             52494..54377
                     /locus_tag="VYO72_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1706631.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            54526..55413
                     /locus_tag="VYO72_000183"
     CDS             54526..55413
                     /locus_tag="VYO72_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1706632.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(55733..56350)
                     /locus_tag="VYO72_000184"
     CDS             complement(55733..56350)
                     /locus_tag="VYO72_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1706633.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(56765..56978)
                     /locus_tag="VYO72_000185"
                     /pseudo
     CDS             complement(56765..56978)
                     /locus_tag="VYO72_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(57463..57543)
                     /locus_tag="VYO72_000186"
                     /pseudo
     CDS             complement(57463..57543)
                     /locus_tag="VYO72_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            57659..58552
                     /locus_tag="VYO72_000187"
     CDS             57659..58552
                     /locus_tag="VYO72_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706634.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            58549..59748
                     /locus_tag="VYO72_000188"
     CDS             58549..59748
                     /locus_tag="VYO72_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1706635.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(60101..60868)
                     /locus_tag="VYO72_000189"
     CDS             complement(60101..60868)
                     /locus_tag="VYO72_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706636.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(60885..61580)
                     /locus_tag="VYO72_000190"
     CDS             complement(60885..61580)
                     /locus_tag="VYO72_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706637.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(61585..61950)
                     /locus_tag="VYO72_000191"
     CDS             complement(61585..61950)
                     /locus_tag="VYO72_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1706638.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            62090..62563
                     /gene="nrdR"
                     /locus_tag="VYO72_000192"
     CDS             62090..62563
                     /gene="nrdR"
                     /locus_tag="VYO72_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1706639.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            62564..63733
                     /locus_tag="VYO72_000193"
     CDS             62564..63733
                     /locus_tag="VYO72_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1706640.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            63734..64630
                     /gene="dnaI"
                     /locus_tag="VYO72_000194"
     CDS             63734..64630
                     /gene="dnaI"
                     /locus_tag="VYO72_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1706641.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            64627..65340
                     /locus_tag="VYO72_000195"
     CDS             64627..65340
                     /locus_tag="VYO72_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1706642.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            65354..66664
                     /gene="der"
                     /locus_tag="VYO72_000196"
     CDS             65354..66664
                     /gene="der"
                     /locus_tag="VYO72_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1706643.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            66755..67090
                     /locus_tag="VYO72_000197"
     CDS             66755..67090
                     /locus_tag="VYO72_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706644.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            67230..67565
                     /locus_tag="VYO72_000198"
     CDS             67230..67565
                     /locus_tag="VYO72_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706645.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNVADIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            67750..68541
                     /locus_tag="VYO72_000199"
     CDS             67750..68541
                     /locus_tag="VYO72_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706646.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            68534..69175
                     /locus_tag="VYO72_000200"
     CDS             68534..69175
                     /locus_tag="VYO72_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706647.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            69179..69829
                     /locus_tag="VYO72_000201"
     CDS             69179..69829
                     /locus_tag="VYO72_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1706648.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGNNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISKDISDLCTDVLAVENGHIQYVKDIQS"
     gene            69840..70127
                     /locus_tag="VYO72_000202"
     CDS             69840..70127
                     /locus_tag="VYO72_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706649.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            70273..72786
                     /gene="secA"
                     /locus_tag="VYO72_000203"
     CDS             70273..72786
                     /gene="secA"
                     /locus_tag="VYO72_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1706650.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            72867..73898
                     /locus_tag="VYO72_000204"
     CDS             72867..73898
                     /locus_tag="VYO72_000204"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1706651.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            73900..74931
                     /locus_tag="VYO72_000205"
     CDS             73900..74931
                     /locus_tag="VYO72_000205"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1706652.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMELENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            74970..75338
                     /locus_tag="VYO72_000206"
     CDS             74970..75338
                     /locus_tag="VYO72_000206"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1706653.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            75328..76431
                     /locus_tag="VYO72_000207"
     CDS             75328..76431
                     /locus_tag="VYO72_000207"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1706654.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            76450..78465
                     /gene="recG"
                     /locus_tag="VYO72_000208"
     CDS             76450..78465
                     /gene="recG"
                     /locus_tag="VYO72_000208"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1706655.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            78781..79761
                     /locus_tag="VYO72_000209"
     CDS             78781..79761
                     /locus_tag="VYO72_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1706656.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        24179 a        14830 c        17813 g        23062 t
ORIGIN      
        1 gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta gtgttattat
       61 acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc tttgtggtat
      121 aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat gagagattta
      181 ttatctaaaa aaagtcatag gcaattagaa ttattagaat tattatttga acataaacgt
      241 tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc agtcaaagat
      301 gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc tactaatggt
      361 atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca tttctttaaa
      421 cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg tcaagctgag
      481 agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat tagccaaatc
      541 aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt tcaaatcatt
      601 ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa atattatttc
      661 ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt agaattggtt
      721 tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa gttgctccta
      781 gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa agattctttt
      841 aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt tgctcagagt
      901 tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt atttgtgtct
      961 tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt aaaaaaggat
     1021 agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat ttcagtcaag
     1081 tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa taccgcacat
     1141 ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg gaatacaatc
     1201 aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga gctttctcac
     1261 tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct atcttatacc
     1321 ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc taaactaaag
     1381 gttttagtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga gacactttct
     1441 tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt atcaaaggaa
     1501 tctttagaag attcacctta tgatatcatt atttctaatt ttattattcc tcctattgaa
     1561 aataagagac tcatctattc aaataatata aacacggtct cactcatata cttgttaaat
     1621 gccatgatgt ttattcgatt agatgagtaa ccaaaaataa caaaaaaacg ctatttcgcg
     1681 tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg tttttgttaa
     1741 gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc tctaaaactc
     1801 ttgctttttt tgtagaagat acgaaaaaag ccataaaacc aaggcttttc ctgttttatg
     1861 tagatgttta cacatgaaaa ttgaagtatt ttcaaaagct aattggagtg attttattca
     1921 tgatgggata aatgatctgg ccaaaaatga ttgagaaata gttgcttaaa aagcatttgc
     1981 atgatactat atattgaaag gaggtgataa tatggtagaa caaagaaaat caattaccat
     2041 gaaagatgtt gctttagaag caggagttag tgttggaact gtttcacgtg taattaataa
     2101 agaaaaaggc attaaagaag taactttgaa aaaagtggaa caagcgatta aaactttgaa
     2161 ttacattcca gattactatg ctagaggaat gaaaaaaaat cgaacagaaa cgattgcaat
     2221 cattgtacca agtatctggc atcccttctt ttcagaattt gctatgcatg tggaaaatga
     2281 agtctataag agaaataaca aattactctt atgttctata aatggtacaa atagagagca
     2341 agactatctg gagatgttgc gtcataataa agttgatgga gtggttgcca ttacctatag
     2401 tccaattgaa cattacttga cgtcaggaat tccctttgtt agtattgacc gcacatactc
     2461 agatattgcc attccttgtg tttcatcaga taatgatgca ggtggaagag aagcagctaa
     2521 acaattaatt agtaaaggat gtcagcattt agcctttgtg ggcggacata atacaaccat
     2581 taatgaaacc aaacgtcgta gaatttcatt tgaaaagtat gtccaagagc ataaaatacc
     2641 tcttagtatt tttgatttgg atgagacagt tactgactat tatggaaagc tagagagttt
     2701 cttggaagaa aattcttcta tagatggaat ttttacaatc aacgatttta cagctttgga
     2761 tgtgattgaa atactagaaa aaaatggcaa acgtattcct catgatgtcc aaattattgg
     2821 atacgatgga attaaaatgg ctggagatag agattatcta ctttcaacta ttgaacaacc
     2881 attggaagaa atggcaaaag aagcggttcg tattttgttt gatataattg atggaaagac
     2941 tgttaatttg cagacaatcc taccagtaaa atttgttgaa ggaaaaacaa caaaaaatga
     3001 aaataagtct tgacagaaag cgctatcaat gatagaatga attcagataa aaagatttat
     3061 ttttaaaaca aaaatgaaac gtttcaaaaa aagaaataaa aagacagcgc caagcgctat
     3121 cttttataga aaaaatgaaa cgtttcaaaa aaaggaggtt gctatgaata gcaaagcgaa
     3181 gcaagtttct ctttgggaaa gaatcaagaa acaaaaactc ttgttattga tgactgtccc
     3241 cggtttagtt ttaaccttta tctttaaata catccctatg tatggggttt taatcgcatt
     3301 taaagattac aatcctttaa aaggaatttt agggagtgat tggattggtt tttctgagtt
     3361 tacaaaattc atatcctctc ccaactttgg tatcttgtta gccaacacat taaaattaag
     3421 tatctatggt ttattgcttg gctttttacc accaatcatt cttgcgatta tgctcaatca
     3481 actcttgagt gaaaaagtca aaaaacgaat tcagctcatt ttatacgcac caaactttat
     3541 ctcagtcgtt gttattgtcg gtatgatttt cctcttcttt tcagtgggag gaccaatcaa
     3601 caattttctt tctatgtttg gaatgaaggc tgacttcttg acaaatccag acttctttag
     3661 acccttatac atctttagtg gtatctggca aggaatgggc tgggcttcaa cgctctacac
     3721 ggcaacattg gtaaatgtag atccagcctt agtagaagca gctcgactgg atggagccaa
     3781 tatcttccaa cgaatctggc acattgatat tccagctctt aagcctatta tggttatcca
     3841 atttgtttta gctgcaggtg gaattatgaa tgtcggatat gaaaaagcat tcttgatgca
     3901 gacatcgtta aatttgccaa cttctgaaat tatctcgaca tatgtctata aagttggtct
     3961 tgtatcagga gactattctt actcaacagc ggttggtttg tttaatgcag tgattaacgt
     4021 agtattgctt gttgcagtta accaaatcgt taaacgcatg aataatggtg aaggaattta
     4081 aggaggaaag tatgaaaaat tcgattatgg atacaaaatt tgatagacgt atcttactct
     4141 taaataaaat cattattgtc tttatcgttt tgatgacttt gcttccttta ctttatatcg
     4201 tcgtagcatc ctttatggat cctaaggttc tggttagtag agggattagc tttaatccag
     4261 ccgattggac tgtagaaggt taccagcgtg tattcagtga ccaatctatt ctaagaggtt
     4321 ttatcaattc tctactatac tcttttggat ttgcagcttt aacagtattg ctatctgtgt
     4381 ttacagctta tcctctttct aagaaagact tggttggacg tcgttggatt aactacttct
     4441 tgattgtgac tatgttcttt ggtggtggtt tagtcccaac ttacttgctc gtaaaagaat
     4501 tgggaatgct caatactcca tgggctatca ttgttccagg tgctgtcaat gtttggaata
     4561 ttattcttgc tagggcctat ttccaaggat tgcctgaaga attagttgaa gctgctgtca
     4621 ttgatggagc gaatgacttg cagattttct ttaaaatcat gcttcctctt gcaaaaccaa
     4681 ttatgtttgt tctcttcctc tatgcttttg taggacagtg gaactcatac tttgatgcaa
     4741 tgatttatat caaggatcca aacttggaac cattgcaact tgtacttcgt aaaattctca
     4801 ttcagagcca accaggtcaa gacatgattg gagcacaagc ggctatgaat gaaatgaaac
     4861 gtttagctga attgattaaa tacgcaacta ttgtcatttc cagcttgcca ttgattgtta
     4921 tgtatccatt cttccaaaaa tactttgata aaggaattat ggctggttca cttaaaggat
     4981 aaaaaaagaa aaaataaaag gagttttctc atgaaattca aaacattctc aaaatcagca
     5041 gttttgttga cagctagttt agcagtactt gcagcctgtg gctcaaaaaa tacagcttca
     5101 agtccagatt ataagttgga aggtgtaaca ttcccgcttc aagaaaagaa aacattgaag
     5161 tttatgacag ccagttcacc gttatctcct aaagacccaa atgaaaagtt aattttgcaa
     5221 cgtttggaga aggaaactgg cgttcatatt gactggacca actaccaatc cgactttgca
     5281 gaaaaacgta acttggatat ttctagtggt gatttaccag atgctatcca caacgacgga
     5341 gcttcagatg tggacttgat gaactgggct aaaaaaggtg ttattattcc agttgaaaat
     5401 ttgattgata aatacatgcc aaatcttaag aaaattttgg atgagaaacc agagtacaag
     5461 gccttgatga cagcacctga tgggcacatt tactcattcc catggattga agagcttgga
     5521 gatggtaaag agtctattca cagcgtcaac gatatggctt ggattaacaa agattggctt
     5581 aagaaacttg gtcttgaaat gccaaaaact actgatgatt tgattaaagt cctagaagct
     5641 ttcaaaaacg gggatccaaa tggaaatgga gaggctgatg aaattccatt ttcatttatt
     5701 agtgataacg gaaacgaaga ttttaaattc ctatttgctg catttggtat aggggataac
     5761 gatgatcatt tagtagtagg aaatgatggc aaagttgatt tcacagcaga taacgataac
     5821 tataaagaag gtgtcaaatt tatccgtcaa ttgcaagaaa aaggcttgat tgataaagaa
     5881 gctttcgaac atgattggaa tagttacatt gctaaaggtc atgatcagaa atttggtgtt
     5941 tactttacat gggataagaa taatgttact ggaagtaacg aaagttatga tgttttacca
     6001 gtacttgctg gaccaagtgg tcaaaaacac gtagctcgta caaacggtat gggatttgca
     6061 cgtgacaaga tggttattac cagtgtaaac aaaaacctag aattgacagc taaatggatt
     6121 gatgcacaat acgctccact ccaatctgtg caaaataact ggggaactta cggagatgac
     6181 aaacaacaaa acatttttga attggatcaa gcgtcaaata gtctaaaaca cttaccacta
     6241 aacggaactg caccagcaga acttcgtcaa aagactgaag taggaggacc actagctatt
     6301 ctagattcat actatggtaa agtaacaacc atgcctgatg atgccaaatg gcgtttggat
     6361 cttatcaaag aatattatgt tccttacatg agcaatgaca ataactatcc aagagtcttt
     6421 atgacacagg aagatttgga caagattgcc catatcgaag cagatatgaa tgactatatc
     6481 taccgtaaac gtgctgaatg gattgtaaat ggcaatattg atactgagtg ggatgattac
     6541 aagaaagaac ttgaaaaata cggactttct gattacctcg ctattaaaca aaaatactac
     6601 gatcaatacc aagcaaacaa aaactagagg ttgattatgg gagataagaa atacacagta
     6661 gaaaaagcca atcgttttat agcagaaaat aaacatctcg ttaatactca atataagcct
     6721 gaagaacatt tttcagctga gattggttgg atcaatgatc caaatggatt tgtctatttt
     6781 cgtggagaat accatctctt ttatcaattc tatccatatg atagtgtttg ggggcctatg
     6841 cactggggac atgctaaaag taaggacttg gtgacttggg agcacttgcc agtggcactt
     6901 gctcctgacc aagattatga ccgaaatggt tgtttctcag gctctgccat tgtcaaggat
     6961 gatcgcctct ggctcatgta cactggacat atcgaagaag aaaccggtgt ccgccaagtg
     7021 caaaatatgg cattttcaga tgacgggatt cactttgaaa agattgaaca aaatccagtt
     7081 gcaactggat cagacttgcc agatgagttg attgctgctg attttcgtga tccaaaactc
     7141 tttgaaaaag atggacgcta ttactccgta gtagctgcca aacacaagaa taatgtgggc
     7201 tgtatcgttc tactagggtc cgataaccta gtagaatggc agttcgaatc catcttttta
     7261 aaaggggtag aacaccaagg ctttatgtgg gaatgcccag attacttcga gttagatggg
     7321 aaagattgcc ttattatgtc acccatgcgt tatcagcgtg agggagactc atatcataac
     7381 atcaactcat cgcttttgtt cacgggtaag gtagattggg gagaaaaatg ttttatccca
     7441 gaatcagttc aagaaattga tcatggccaa gacttctatg cgcctcaaac attgttggac
     7501 gatcaaaatc gtcgtatcct gattgcttgg atgcagacat gggggcgtac ccttccaacc
     7561 catgaccaag aacacaaatg ggcatgtgcc atgactttac ctagaatttt aagattggaa
     7621 gatggcaaac taagacaatt ccctgttaaa aaaggccaat atcaaatcca aatagataaa
     7681 gattgtcatt accacttagg aaatgatata gattatcttg aatttggtta tgatagtaat
     7741 gcgcagcaag tttacattga tcgtagccat cttattcaaa aaattctagg tgaagaagaa
     7801 caggacacta gtcgacggta tgtagatatt gaagctaaag aattggaagt tgttctagat
     7861 aaaaattcca tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc aacttattac
     7921 ttaacggtgc cagctgagct atcacgaatt gattaaaaat taagttattt ctcctaaaga
     7981 aaaagttctc tttctaaaat agtggaaaga ggactttttg tgttttgggt atataagctt
     8041 agtttatggt atttgtaaaa ttggtgttgg attatgattt aagctagttt tctaaagaat
     8101 ttgaaaaaaa ttttatttaa gcaaaaaaaa cccttggttc caaggctttt cctgttgtat
     8161 ttatatgccc cctacaggga tcgaacctgt gacccacgga ttaagagtcc gctgctctgc
     8221 cagctgagct aaggaggcaa agaaaaaagc tgtattggtg ccgaaacttc acggtttgta
     8281 ttgaacccgc gcaattaagc aggtgggcaa ctcgctctaa ctgaagctgt ttccgtgtga
     8341 gacggcctac atgctgttag aagacttttg tttccctaat aatacaaaaa atagtcggtc
     8401 aacacttaag tgtgaagtcg tacaccacag cgtttctata cttatatgat accacttttt
     8461 caaaaaaaat caagaggaaa gtgcaatttt ttgaaaagga tttcagattt ttcgcaaacg
     8521 gtcgatagct tcctttcttt gagccaaagc ccgttcatat ttaccagtat cttctgcttg
     8581 gaaatagtga tgattacgaa ttttttctgg cagatagtct tgcttgaccc aatttccagg
     8641 atagttgtgt ggatagagat agtcttgggc attccccagt tccttgcttc cactgtagtg
     8701 cccatcacgt aggtgtcgcg gaataggcaa gtgccctgat gttttgaggt cagcaagtgc
     8761 cttatccata gctacatagg ctgagttgga ttttggagaa agggccaaat caatcacgac
     8821 attggcaatg agaatgcggg cttctgggaa cccaatcttc tgggcagcat ccagagcagt
     8881 cacggtatga atctgggcct caggattggc taagccgata tcttcatagg cgataacagt
     8941 caagcgacga gcgagactag gcagatcccc agcctcaatc aagcgggcag tatagtggag
     9001 actggcatcc acatctgagc cacgaataga cttttgcagg gcagatagaa catcatagtg
     9061 accgtctcca tccttgtcca tagtgatgta gcttctctga agactatttt ccatgatgtc
     9121 taaggtgatg tggcgaatgc cctcgtcatt ctcaggggta gagagaacag ctaagtccag
     9181 tgagttaaag gcagagcgaa ggtctccgtt tgtagaggtt gcgatgaaat ccagcgcatc
     9241 ctcatctagt tctattggaa aatcaaaacc acgttcaggg ttacttagag ctatctgcag
     9301 ggcctctttg acgtcttggt tagacagagg ttccaactcg aaaatttgaa ctcggctacg
     9361 aatggcagga gtgacagaga agaaaggatt ttcagtcgtt gctccaatca tgatgaccag
     9421 tccactttcc aagagaggca agaggaagtc ttgcttggtc ttatctagtc gatgaatttc
     9481 gtctagcaat aggacgagac caccagaaaa tttagcttct tccgagattt cttgcagtcg
     9541 ctttttacta tcaactgtcg cattgaaagt tcgaaaggca tacttggtcg ttccagcgat
     9601 ggcagaggca atactggttt tgccgattcc aggagggcca tatagaatca tggaggacag
     9661 gcggttggct tccaccatgc ggcggatgat ttttccaggt ccgaccagat gctcctgacc
     9721 gatgacctgg tcgatggttt tagggcgcat gcgaagcgcg agattgtctg gcatagcagt
     9781 cctttctagc gtggatttga gtagaatgac tcatctacta tatcttacta tgtccattct
     9841 agcctattag ttgtgatatt tcaatggttt tgtaataatc agggagtgag atagaatctt
     9901 ttttactatt taatttaatg aggagaggta tcagcatgag agatttgatt ttccttaaag
     9961 ctcaaaatag gatagttgag cctaaagaag tggaagtgct gacttgagaa ataatattgc
    10021 tgaatgtcat tgtatgaact ataatgaaaa gagaggtgat aagcaatgga aatgatggac
    10081 caagtcagga aattttgatt tttacaaaac aaattcgtca ttggattctt agtgatcaag
    10141 ttatttcagg gaaaagaaaa cttttcttcc gggaagatac tccaaaagag attttagatt
    10201 tgtacgaaaa cattaaatct aaacttgatt ttgcttacca ataagtttat tctaataatg
    10261 ggttgaaaaa atatgaaaaa tagaataatt gatgtttttg aagtagtaaa tcgcatcctt
    10321 gtaataactg ttgaaaatcc tgatttcgaa gacttgagag ttaatcatac tcaatgaaaa
    10381 tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggtaa ggcgacgttg
    10441 acgtggtttg aatttgattt tcgaagagta tcagtttgta aaaattggag ataaaaaata
    10501 tagagtacgc agtgttccta tgattcattc aactccgcct caatctgtct tagatcgaga
    10561 tacttttaca attgactata cagatgatga attgctcgat aaagaagcag tttttactac
    10621 tcattagaaa aataggtctg aataaattgg cttcccttag aaccacatct aggggctttt
    10681 atgtataata gaataataag tatcactcct ttacaatacg tgtaacacgt gttataatgg
    10741 tgttgtcagg aggtaaaagc gctatgccta tgacacaaaa agagatggtt aaactcctta
    10801 cggcccatgg ttggataaag actagaggcg gtaaaggctc ccatattaaa atggagaagc
    10861 aaggggaaag acttatcaca atccctcatg gtgagctgaa taagtacact gaaagaggga
    10921 taagaaagca agctgggttg taaaattcag cccctgtttt ttgatatgga ggtagtgaaa
    10981 tgttagttac gtatccagct ttattttatt atgacgacac agacggaaca gaagcgactt
    11041 attttgtcca tttcccagat tttgaatact cagctacaca aggagagggg atttctgagg
    11101 ctttggctat ggggtcggag tggctaggga taactgttgc agatttgata gagagtgatg
    11161 gagagttacc tcagccatca gatatcaata gcttgtcttt aattgataat gatcctttta
    11221 aagatgatga agatttcgtg tcaacctatg accttgataa atcttttatt tctatggtat
    11281 ctgttgatgt atcagaatac ctaggaagtc aggaacccat aaaaaagact ttgaccatac
    11341 caaaatgggc agataagttg ggacgagaaa tgggacttaa cttttctcag actttgacag
    11401 acgctattgc agataagaaa gttcaagcct aagattaagc gtggtatcgt ggtaatagtc
    11461 aataaaaaag cacgtccact tgtgctagtt actcgcctat tgattttata gatttattag
    11521 ccctttcgag ggctttttat attgattttt atgagaaatg aagaaatcag acttttaaga
    11581 aaatcactga taccaagggt ttaaatgagg taatatggta taattaggac ataaaataat
    11641 tttgtggtaa gatggtagta tctattttag catatttccg agcaatcggg gcgattaaag
    11701 agtcgcatag aaagaggaca aaatggcaac atacggattt ttagatgttt tagaggaaga
    11761 gttggacaag aactttccct ttgactttga gattagctgg gacaaacgca accatgcggt
    11821 agaagtgagt tttctattgg aagcgcaaaa tgctgcaggt gtggagatgg tggatgaaga
    11881 cggagaggtt tcatcagatg acattctttt tgaggaagcg gtccttttct acaatcctgc
    11941 caagtcaaca gtcaatgagg aagactattt gactgttatt ccttacctgc ctaaaaaagg
    12001 attttcccgt gaatttttag cttattttgc gcttttcctt aaagatactg ctgaggttgg
    12061 gctagatgtc ctcatggact ttttggaaga cccagaagca gaggaattta tcatggaatg
    12121 gaaccaagaa gtctttgaag aaggaaaagt tggcttggaa gagggagaat tttatcctta
    12181 tccaaggtat tagaaaagat tctaagtgga catttttaaa taatgaattc aaggagaagg
    12241 gggagattat gctagaaaaa gtcaaacagt ttttcaggag caggtcagct aaaactgagc
    12301 cgtcagttga tattcttccc cgcaatcgct ttgaggatct agatttcgag agagtattga
    12361 agtcaggagc tcgtcgcctt gttaatgagg aaggacgcta tgctgaggat gggaaaatca
    12421 cagaacttga atttcctgaa gattttgcgg aatttgaatt tctagttggt tttaagacgg
    12481 aggaagaaga gcagtttcag caactattag ctcgtttaaa tagtattgac aatgctattc
    12541 agtcctattt ggaaagtgag atgcaacaac ccatccctca gtatgccaag gatctcggct
    12601 atactcagaa gaggtgggag aaaacctttt acttccatcc ttggatatta agtggtgagg
    12661 aaaacccgcc taatcttcgc tatgttgcag attatgtaaa tgatgagttt acggtttatt
    12721 ttgctaaaaa acatggcaga tggcaagcat actgggatgc agagtgccaa aaagtaatcg
    12781 aagaaagcta gctcgtattt tcctagagag taattgttat catagaaaag agtaaatatc
    12841 atggaattat tgaatagcag aatggatttc caaggttgca agattgccct cttttgtggg
    12901 gataagctac tgacgatttt gcgtgatgac aaggacgata tcccttgtcc caacatgtgg
    12961 gagttgccag gtgggggaaa gagtgtcagg gaaaatctga tatagttttg cattaaaaga
    13021 atatcctttc aaggttattc ttttttaatt ttgtcccaaa ataattgact ttgtcccaaa
    13081 aatatagtat tatttgtata aggaggaatg aatcatgaaa aaatcagatg ttcttgattt
    13141 aataaagtat cattatgagg gcagagagac agaatttaga aatcaatcca tagcaattgc
    13201 tcggaacttc aataaacatg gtgatacaca aatagcacaa tatattatgg ggttaatgtc
    13261 tcaaagtgat agattcatgc cacaaataga aaatcctagt gagtatttga ctcctgctaa
    13321 actagatatt ggtcctctcc cattgcctct ttcaattatg aatgatttaa aaggaataat
    13381 aaacgctgtc aatcatcata ttggaataaa taaattttta tttgtgggat ctccaggtac
    13441 tggaaaaact gaaagtgtaa agcaggtggc tagacttatt ggcaaggaat tacttgtagt
    13501 agatttcagt cacttagtag atagtaagct agggcaaaca gtcaaaaact tagcaactct
    13561 ttttaatgaa atcaataatc ttcctttcaa gcaaaattat atcatcctat ttgatgaaat
    13621 tgattccata gtgttggata gggttaatca gaatgattta agagaaatgg gacgagtgac
    13681 ttctgccttt ttaaaggagt tggataggct gtcaccagaa attgtattaa ttgcaacaac
    13741 aaatcttttt gaaaatcttg ataaagcagt tacgagaaga ttcgatgcca taattgactt
    13801 tgaccgttat actgatgaag ataaagtaga agtagctact attattttaa atgagttatt
    13861 aaagcaattt aagaatgtag ctagagattt aaaattattt aaaaaaatta tcaatagtgc
    13921 caatgtaata ccgaatcctg gtgatttgag aaactcaata agaacgtcat tggcatttag
    13981 tgacccatca gatccgcatg attaccaaaa acgcctgcta agaagtttgc ataatggtag
    14041 aaatttatct atttctaaat tatcgaagct aggttttact gttagagaaa ttgagatttt
    14101 gacaggtatt tctaagagta gtgtatcacg agagttaagc gaggattaaa atgaatacat
    14161 tattgacatt acgaggtaaa agttttacac caaagtcagc aaaggggagg ggaccgataa
    14221 cgattcccgc agattctatt gttacgctaa accatttaaa tgaactttat acatcccttg
    14281 aacgagtaaa agaatattgg tctaataaca caatcattga tggagtactt attagtgtgt
    14341 attataatcg tgtcctagct aagagcaatc gtatcgatgg tttttttaat gtgggtggcg
    14401 gaaatgcaat tccaaatgaa acgattgtgg gtgcaaaatt tagtaatgat aagagtaggc
    14461 atattattac acactacatt tcaaaggaag tgttagataa gacaattgag catactaaaa
    14521 aagttataac aatattcaaa gattattttg ctagtgctcc catgacgagt atggtgttct
    14581 ccgactcttc aaaatttaat caaattgatt attctaagta tggtctgtcg aaatcaaaat
    14641 tcaaacaata cttaagagac gcttgctttg tcaaaggatt tggtattgaa caggcagata
    14701 tgtctactat acgtaattct attgtaacaa tctacgatgt aaaaactaat ctcttaacat
    14761 tacttaaaca acttgatatt gatgtttcag aagctaacat catggaccag acaactgttt
    14821 tacttgacga aaaaaatatt gagttactac tgctaaaagc accttatcta gtatcaatga
    14881 tagtagaaga tttttctagc ctgtcaccag agaattttta taatgatggg aacacttttt
    14941 ataataatct cccttttcca actaatgaac ctattattgg tgtcatcgat acgttgtttg
    15001 atgatagagt ttatttcaat gagtgggtag agtatcatga tttaatttca ccagatatta
    15061 gcaaaggaag tcaagactat aagcacggta cagcagtttc ctcggtaata gtagatggag
    15121 ctagtttgaa tccaaaacta gatgacggat gtggaagatt tagagtcaga cattttggga
    15181 tatctttaca gagtggtttc aattccttca caattatcaa acagattaga gaaattgtgt
    15241 ctcaaaatcc tgatattaag gtttggaacc tttcgcttgg atcaaatgat gaaattaggg
    15301 aaaactttat ttctgtcgag ggttcgttgt tagacgagat tcaatttgat aacgatgtaa
    15361 tttttattat tgcaggcact aatgggattg cccctgatgg acaacgaaaa aagattggag
    15421 caccagcaga ttcactcaat tcaattattg taaattctgt tgattttagc aatcaagtcg
    15481 tttcttattc acgcgaagga gttgtcctgt ctttctttat caaacctgat gtttcatact
    15541 atggcggggg gaacggagac ttcataaatg tttgtgaacc actagggctg gctcgagtag
    15601 ctgggaccag ttttgcggct ccatttattg ctagaaaaat ggcttacctc attcatatta
    15661 tgggattaag tcgtgaagaa gcaaaggctt tattaattga ttcagcgata ccatggaatg
    15721 ataaaaaaac attcgcagac atttctttac ttggatatgg ggttgtgcca atcaaaatag
    15781 aagatatttt gtctacacct gatgatgaaa ttaaatttat agtctcagat gtttctagag
    15841 catatgaaac ttataattat gatttcccag ttccaatttc taaagaacac tatccatatg
    15901 tagcaaaggc cactatgtgc tattttccaa agtgttctag aaatcaagga gttgactata
    15961 ctaatacgga aatgcaactt agtttgggag ttttagataa gaaaggcatt aaaacaatta
    16021 ataacgacaa tcaatattct gaaaatgcac caggatatgt gagagaaaag tcggcacgaa
    16081 atatttttag gaaatgggat aatgtcaaac atttaggaga aaaattttct tctcgtaaaa
    16141 aagctaagcc gattctgaat ccttctaatc ctcaatgggg aatgagtgta aaaacaattg
    16201 aacggttaag aaatgatgat ggttatggta tccgttttgg agtagttgtt actctaaagg
    16261 agttgaatgg tgtcaataga atcgaagatt ttattcaaca agccgaatta cgcggttggc
    16321 tagttaatag attgcaagta gaagctcaag tagacctctt taatagttta aatgaagaaa
    16381 ttgaatttga atagtggata ttttatcctt attctagatc ttaggaacac aagagggcaa
    16441 agatatgaat attacttata tagttggaaa tggtttggat ttgcaatatg gtttgaaaac
    16501 aagatataaa gatttctatg aatttcaaaa taggacttac ataagtagga aagagaacga
    16561 ggaagaatat tcaaatctca tttatgagtc tctattttct gatacagtaa atgattatga
    16621 aaattggtca gattttgaat tgtcaattgg taaattaaca aaagataacg acctcatctc
    16681 ctcaagtata gaaataaagg agaaatttat agatgatttt agtgaaatag ttgatgattt
    16741 aagagaatat ctacgcatac aacaagaaaa aaatcttgag aaaggtaatg caattgactt
    16801 tataagcact ctagataata tgaggacctc tctccctgta attaatcaac ctgctatcga
    16861 taaaaaatat aatgaaaatc tatatcaaca cgatattgtg aatatattaa ctcttaatta
    16921 cacaaatgta atcgataaat tatataatga gtcagcaaaa tcatttagca atcaattacg
    16981 aactaataat tataaatttc acattgcgcc tccaattcat gcacatggaa cggtagatat
    17041 ttgcacagtt ttaggagtta gtgacgagac acagatttca aatagttttg atgaagaaca
    17101 aaaagaatcc ttaataaaaa atttagtttt gaagaactat agagaaaata tggatgttaa
    17161 aaatagcgat attataaaaa attctgacat cataattctt tatggggttt ctttgggaga
    17221 gactgatggg tatatctgga atcagattgc tgaacaatca atcagaagtt ctgttcctgt
    17281 cataatttac cattatgtac ctcattttga tgcaggaaac cccactagag taaaacgctt
    17341 atatagaaat gtagaagaca aattcataca aaatagtgga attgatttag agttagagaa
    17401 gaaattaaga gataacctta ttgttgttat tggaaagact atttttaatc tgatggaaag
    17461 gtaagcaaaa tacataatgg aaacatggca agagttaaaa gttacagtga agcgtgaggg
    17521 agaggagttg gtttccaatc tcttgattga gctgggagcg caaggagtcg caatcgaaga
    17581 cagtatggac tatgtgggaa atgttgaccg ctttggcgag attttcccag aggtggagca
    17641 gcaagaagaa atcgtagtga cagcctacta ccctgacacg gtggatgtga cagtggttga
    17701 ggcggatttg caggctcgtc tagcagaatt gacagatttt atggatttgg gagagttaaa
    17761 aataggtacg actgccttgg ctgaggaaga ctgggcagac aactggaaga aatactatga
    17821 acctgctcgc atcactcatg atttgaccat cgttccctct tggacagact atgaggcgac
    17881 tgcgggagaa aaaattatca agctggatcc tggcatggct tttggtacgg gaacccaccc
    17941 aactaccaag atgagcattt ttgccttgga acaggttctt cgtggtggcg aaacggtgct
    18001 agatgtggga actggttcag gggttctctc tattgccagc tcgcttctgg gggctaaaga
    18061 aattttcgcc tatgacctgg atgatgtggc agttcgtgtg gctcaggaaa atattgagct
    18121 caaccctgga atggaaaata tccatgtagt ggcaggcgat ttgcttaaag gcgtggagat
    18181 tgaagcagat gtcatcgtgg caaacatctt ggcggatatc ctcattcatc tgacagagga
    18241 tgcttatcgc ttggttaagg atgaaggtta cctgatcatg agtggcatta tcaaggataa
    18301 gtgggacatg gtgcgcgagt tggctgaatc agctggattt ttcctcgaaa ctcacatggt
    18361 tcaaggggaa tggaatgcct gtgtctttaa gaaaaccaag gatatctctg gtgtgattgg
    18421 aggctagcat gcagcagtat tttgtaaaag gcagtgctat ctctcctgtc actatcgaga
    18481 acaaggaaac cagtaagcat atgtttcagg ttatgcgctt gaaagaagag gatgaggtta
    18541 ccttagtctt tgatgatggc atcaagcgct tggcgcgcgt gctggatatg gaaaatcgtc
    18601 agtttgagtt ggtccaagaa ttaaatgaca atgtggaact accagtccaa gtgaccatcg
    18661 catctggatt tcccaaggga gacaagctgg agttcatcgc tcaaaaagta accgaactgg
    18721 gtgctagcca aatctgggcc tttcctgcag actggtcagt tgccaagtgg gatggcaaga
    18781 aattgggtaa aaaagttgaa aaactagaaa aaattgccct tggagcagcc gagcaaagca
    18841 agcgtaatat tgtaccaagt attaaacttt tcgagaaaaa agcagatttt ctagctcagc
    18901 tggaccagtt tgactctatc atagtagcct atgaagaatc agctaaagaa ggagaagccg
    18961 ctgcgcttct gcaagcagtc actggtcttg aaacaggagc caaactgctc tttatctttg
    19021 gtccagaagg cggtctctca cctgcagaaa tcgaaagttt tgaagctaag ggagccgttt
    19081 tggcaggcct aggtcctcgt attttgcgag cagaaacagc accgctttac gctttatcag
    19141 cccttagtgt tttagtagaa ttagagaaat aagaggaaga aaatggaaca aaaacaccgt
    19201 tcagaatttc cagagaagga actctgggac ttaacagccc tataccaaga ccgtgaggat
    19261 ttcttgcgtg caatcgagaa agctcgcgaa gacatcaacc agtttagccg tgattacaag
    19321 ggcaatcttc acacttttga ggatttcgag aaggcctttg cggaattgga acagatctac
    19381 attcagatga gccatattgg caactatgct tttatgcctc agacgacgga ctatagcaat
    19441 gacgaatttg ccaatattgc ccaagctggg atggaatttg aaacagctgc cagcgtagcc
    19501 ttgaccttct ttgacgatgc cttggtggca gcagacgagg aagtcttgga ccgtttgggt
    19561 aaattgccac atttaacagc tgccattcgt caggctaaaa tcaaaaaagc ccactactta
    19621 ggggcagatg tggagaaggc cttgacaaat ctcggtgaag ttttctatag tccgcaggac
    19681 atttatacta agatgcgagc tggggatttt gaaatggctg actttgaagc ccatggcaag
    19741 acctataaaa acagctttgt cacctatgag aatttctacc aaaatcacga ggatgctgag
    19801 gttcgtgaga aatccttccg ttccttctca gagggacttc gtaagcacca aaatacggct
    19861 gcagcagcct atctggctca ggtcaagtct gaaaaactct tggctgatat gaagggatac
    19921 gactctgtct ttgactatct tctagctgaa caagaagtgg accgtgtcat gtttgaccgc
    19981 cagattgacc tcatcatgaa ggactttgca ccagtcgctc agagatacct caagcatgtt
    20041 gccaaggtaa atggtcttga aaagatgacc tttgcagact ggaaattgga cttggacagc
    20101 gccctgaatc ctgaagtgac tattgacgat gcctatgatt tggtcatgaa gtcggtagaa
    20161 cctttggggc aagaatattg tcaggaagtt gctcgttacc aagaagagcg ctgggtggat
    20221 tttgctgcta acagtggcaa ggattccggt ggttatgcgg cggacccata tcgcgtacac
    20281 ccttatgtac tcatgagctg gacaggccgt ttgagcgatg tctatacctt gattcatgaa
    20341 atcgggcatt ctggtcaatt catcttttca gacaatcacc aaagctattt caacgcccac
    20401 atgtcgacct attatgttga agcaccgtca accttcaatg aattgctact cagtgattac
    20461 ttagagaacc agtctaatga cccacgtcaa aaacgcttcg ctctggctca tcgcttgaca
    20521 gacacctact tccataattt catcacccac ctcttggaag ccgccttcca gcgtaaggtg
    20581 tatacattga ttgaagaagg ggagaccttt ggagcaagca agctcaacag cattatgaag
    20641 gaagttttga cagatttttg gggcgatgcc attgaaatcg acgacgatgc agctttgact
    20701 tggatgcgcc aagctcacta ctatatgggc ttgtatagtt acacttactc tgctggtctt
    20761 gtcatctcga cagctggtta ccttcatctt aaaaactcag aaactggagc tgaagactgg
    20821 ctcaatctcc tcaaatcagg tggtagcaag acaccacttg agtcagccat gattatcggt
    20881 gctgatattt caacagacaa accactccgt gataccatcc aattcttgtc tgacacagtt
    20941 gaccagatta tcgcctacag tgctgagttg ggggagtaag gggatagaga ggttgttata
    21001 gaatgggtat ggacagttat ttgcttaaaa gtccatgttt aaatccccca ttccttttcg
    21061 aggaattctt tgcccttctc tgtaatggta agtgaacgtg gcgtttgtgc agggatgacc
    21121 aattgttttt cactgaaaaa ttctaaaaga gcattgccga gagctccgcc gacatgattt
    21181 ttacgttcgc tccaatccaa acatttaggg caaaatttcc gttttttctt tttcaattca
    21241 tccgtatcaa tgtgtaattt tctttggaaa taagacttcc cagcttcagt gagttggaag
    21301 tctttttctg atcggattga agattactgg actttcagta aacccagctc gtagcttggc
    21361 accagctgtc ttggtgggcg gcgcagccct tcaacaagtt tggattttca tccttgcacc
    21421 aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa cagaagaata
    21481 attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc gtatgatact
    21541 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtaggtatgg ttactgactt
    21601 cgtcagttct atccacaacc tcaaaacagt gttttgagta acctgcggct aacttcctag
    21661 tttgctcttt gattttcatt gagtatgact ttagcggttg tcaattttct ctggataaag
    21721 gtcgtgttgg aagaggcgtt gttctgccaa gccctcatac ttagttcctt gcttaccgta
    21781 gttgtagtag gggttgattg aaatgccacc gcgcggagtg aatttccccc agacttctaa
    21841 atagcgaggg tctagcaagt tgaccaagtc tttcccgatg gtgttgatac agttttcgtg
    21901 gaaatctccg tggtttcggt agctaaatag atatagtttg agggattttg actcgacaca
    21961 gagtttgtca ggaatgtagg aaatatgaat cgtcgcaaag tctggctgag cagtgatttg
    22021 tcccagcaga gacatatcga ggatatggtg acgaatgccc tgttccttag cgatttctct
    22081 attaatttga atttcgaggt gatgacgttg gccgtaggca aaggtgacag cttcgactgt
    22141 ttcatagtgt tgcatggccc agaaaaggca ggttgttgaa tcttgaccac cactaaagac
    22201 gaccaaggct gattgacgtt tcatagtact ccttccaaaa tgggaaatgt tcagagcatg
    22261 caaaaagctc ccattaggga gctaaaaaat accaaatcga gtttttttag cgatggcata
    22321 tcccaaacat cgtaatattc tacttatata gtaaaatgaa ataagaacag gacaaatcga
    22381 tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt
    22441 tcaatctgct atagtctagc atattttttg aaaaatggca aagggcaaga aaaaagagac
    22501 caaagaaagt acttggtctc tcgtttgatt agctcaattc agcaatgatg gccttgattt
    22561 gttctgctgt gtgaacacct gcaacttgtt tgacaacttg gccgtctttt ttgaagagaa
    22621 gagttggaat agacatgatt ccaaaagcac gagctgtgtt tggattttca tcaacgtcca
    22681 ttttaacgat tttcaagaca tcttctgaaa gttcttcaga caatttgtcc aagattggac
    22741 cttgcatacg acatggacca caccaagttg cccagaagtc tactaagacc aaaccgtctt
    22801 ttgtttcttg ttcgaatgtt gcatctgtaa ttgcttttgc cattgtattt ctcctttttt
    22861 tagttatatt ggcttaaatc ttgtttcatg agatagaaga agatatctcc ataagtccca
    22921 tggtagtcca aattatgacc cttgtaagtt aatttttgga cagggtagta gtctgcgacg
    22981 ccgataaggc aagcttgttg cgaacgttca aagtcttcat aagactcgaa agtcacagtt
    23041 ctttcgttct tgctggcatc tatataggta atttcaatca tgtttaaaac tcctttgttt
    23101 aatgctaact ttattttact ccttataaaa gagaatgtca agaaaaatga ttgcgcacgc
    23161 aacttttttt aaaatcatct taaatcaaga aatccaaacc tgcttccaag ctttcttcga
    23221 cagtcttttg tagcgaggcc agtgtctttt gcccatcatt tgtcaggcag ataaaactag
    23281 agcgtctatc ttgatggcaa cacatgcgac tgagtagacc gcaattttta gcttccaagc
    23341 gagccaccat cctagaaact gcgctcgggc tcagatgaag cttatctggc aggtcaatct
    23401 ggcgtagaga tttttcttca gccaagtcca gatagtagag caggtagaac tctttcaagg
    23461 tcagactttg ctcgctctgt tgggcaatgg tctcttccaa gagactttca atttctttct
    23521 gacgccgatt gaagtcaaac catttttcca aataggtcat agtgtctcct ttctttttag
    23581 agtcataaat agaagaaagt ccattaacgg gcagtctctg cgtcacaaga tgattgcgca
    23641 tgcaataatt atactacttt tcaagaatgc tggcaagctc tgttttttag tggttttatt
    23701 ttttactgtc tatatttttg gtaaaaatca acttttactt ggatgaaggt tttggcttca
    23761 cgtaggagtt gaagaagggt ggcgcgggtt tcaaactctt ctcttgtttt gggcagactg
    23821 cggttccgga agacttccag ataacgttca atttcatcta gcaaatcaga agcaggattg
    23881 gtctggctca gttgacctgc aatttttgaa aagagttgcg ctaagatcag gctttcactg
    23941 gcggcaaggt gacaagtgtt aatctgttgg gccatgtttc tcaggatacg actttgtcgc
    24001 tgtctcatct caaagtagtg gatatggtag tcggtctggt gaaagaggtg gtcagagtga
    24061 tccaaataga ccagtctgag ggcttctttc aaaagcgtgt ctaattctgc taccagctgt
    24121 gctcggttgc gtccgtctcc tctggataaa tagtatttga agcgctggag gatatctttt
    24181 aacttttctt ccaccagcgt gtggtagtgc tggatttcct cttctcgtga aggcatatag
    24241 agattaacaa gcaaggcaaa tcctgtacca atagcaaaga gaaggaattc gttgactagg
    24301 aggtctggag aggttgactc ttgaaccaag agatggctaa ccaaaaccgt gcttggtgtg
    24361 atgccaattt cccagcccat cttgtaggct aaaggaacgt agaaggccag atagaggccg
    24421 agactccaga tatgaaatcc gctcaagtga aaagctagaa caccgatagc cagagctaga
    24481 agcatagaaa aaagacgatt gcgagccagt tttaaagtac ttctacgcgt atcagatagg
    24541 ctcaagagag cgataattcc agccgaaact gctgacgaaa gattgagaaa ataagcaagc
    24601 aggcaggcaa gacaggtagc taagatgagc ttggtcgtac gttggctaat agacataaga
    24661 atttcctaat aagttagaat aaaagcgtaa aagacaagac atgagcaggc ttgccttgat
    24721 gagttatttt ttacgggttg ctgcgtattc ggcaacggcg gtaaagagga catctgtaga
    24781 agaattaagg gctgtttcac atgagtcttg gatgacacca atcacaaaac caaccccaac
    24841 aacttgtatg gcaatatcgt tagaaatacc gaaaaggcta caagcaactg ggataagaag
    24901 gagggaacct ccggcaatac ctgaagcacc acaggctgag atagctgcta ccacactgag
    24961 gacaaaggct gtggcaaagt caacaggaat tccaagagtg ttaactgcag caagggtcaa
    25021 aaggttaatg gtaatcgcta ctccagccat attgatagta gaaccgagtg ggatagaaac
    25081 agaataggta tctgggttga gtccaaggtc atggcagagt ttcatgttga caggaatgtt
    25141 agtcgcagaa ctacgagtga aaaaggctgt cacaccgctg acacggaggc agttccaaac
    25201 tagagagtaa ggattgcgtc tcataaagaa gaaggcaatc aaagggttga ccacaggggc
    25261 aacaaaaagc atagtcgtta ctaatggaac caataaaata ccgtagttgg caaggcttcc
    25321 gactcccttg tcagaaatgg ttttaaaaac aagaccaagg attccaaatg gagccagatt
    25381 gatgatccat tcgacaattt tagaagtcac gtcagcgata gtttttagca attctttact
    25441 atttttactg gcttctctca tagcgattcc aaaaatgact gcccaagata agattccaat
    25501 atagttagca gtaaacaggg cgcgttgact gggctgtcaa ccagtttgag caagaggttg
    25561 ctgaggatct gcccaacccc atctggtggt gcaatttcag tattggcact atttagggta
    25621 atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc gaaagtccct
    25681 atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc ttttgatgtt
    25741 gggaaagggc attggcaacg agggcaaaga ctaggatagg agcaacagct tttagacctc
    25801 caacgaataa atccccgagt agcccaatcc ctgagagatt aggaagggtc agtcctagga
    25861 ttccccacaa agcataccaa tcaagatacg cttgacaagg cttgccttat tccaagcatg
    25921 aatgattctt ttcataataa tctccttttt gtgtagtgat tatgattata gtataaatga
    25981 tagacaaaat caagaatttt ctgtctattt tttgaatatt tatggagaat gagactgatg
    26041 aaaatatggt ataatgaaat aaaggagttt tatatgcaaa aatttattca ggcttatatt
    26101 gaaaagctag atgtgacaac cattatcgag aatattctaa ccaaggtcat ttctctttta
    26161 ctgcttttga ttgtatttta tattgctaaa aaaatgcttc ataccatggt gcagagaatt
    26221 gtcaaacctt ctctaaaaat gtctcgtcat gatgttggac gccaaaaaac catctcacgt
    26281 ttactagaaa atgtgtttaa ttatacgcta tatttctttt tactctactg cattttgtcg
    26341 attttaggtt tgccagtttc tagtttgctg gctggagctg gtattgctgg ggtagcgatt
    26401 ggtatgggag cccaaggctt tctgtctgat gtcatcaatg gctttttcat cctctttgaa
    26461 cgtcaactgg atgtgggaga tgaggtcgtt ctgacaaatg gaccgattac tgtatcgggt
    26521 aaggttgtca gtgtgggaat tcgtacgaca cagcttcgta gcgaggagca agtccttcac
    26581 tttgtcccta accgaaatat cacagttgtt agcaatttct cacgcacaga ctagacctgt
    26641 tattttaagt aatttgtggt acaatagagg gagtttaata aggagaaaag atggttttag
    26701 aaaagcagtt gggcaatggt tgtacctgga tagacctaga cctaggaaag ttgaataaac
    26761 tagaagacct ttctgaaatt tacggtttgg acaaggaaac cattgaatac gcactggata
    26821 gaaacgagcg cgcccacatg gactaccacc gtgaaagtgg gacggttacc tttatctata
    26881 atgtcctaga cgtaaaaaag gacaaggcct actatgagac ttttcccatg acctttattg
    26941 tcgagcatcg tcgcctgatt accattagta ataccaagaa cgcctatgtc attgaacaga
    27001 tgactcgtta tctggagagc catgacacgc tttcgattta taagtttctc tttgccagtc
    27061 tggaaattat cagcaatgcc tactatcctg tcattgagca gatggacaag agtagggatg
    27121 aggtcaatga cctcttgcgc cagcgaacta ccaagaaaaa cctctttgcc ctgtctgatt
    27181 tggagactgg tatggtttat ctgacggcag ctgccaaaca aaatcggatt ttgttagagc
    27241 atattcaagg tcatgccttg tatcgtagtt ttgatgagat tgagagagaa cagtttgatg
    27301 atgccatgat tgaggctcat cagctggtat ccatgacaga cctaatctct cagattttac
    27361 agcagctttc agcctcttac aacaatattc taaacaataa tctgaatgac aatttgacaa
    27421 ccttgactat catttcagtc ttgctagctg ttttggcagt cgtgacaggc tttttcggaa
    27481 tgaatgttcc cttaccttta acagatgagc cccatgcttg gctctatatc agtttggcta
    27541 gtgcaggttt gtggattgtt ttatccttgt tactaaggaa aattgcgaaa aaaagttaag
    27601 aaaaggagcc agaatggcga ttgaaaatta tataccagat tttgctgtgg aagcagtcta
    27661 tgatctgaca gtcccaagcc tgcaggcgca gggaatcaag gctgttttgg tcgatttgga
    27721 taataccctc attgcttgga acaaccctga tggaacgcca gagatgaagc aatggctaca
    27781 tgaccttcgg gacgcgggta ttggcattat cgtagtgtca aataacacca aaaaacgcgt
    27841 tcaacgagca gttgagaaat ttgggattga ttacgtttac tgggccttga agcccttcac
    27901 atttggtatt gaccgtgcta tgaaggaatt ccactatgac aaaaaggaag tggtcatggt
    27961 tggtgaccag ctcatgacag atatacgagc agcccaccgt gcagggattc ggtcaatttt
    28021 agtcaaaccc ttggtccaac atgactcaat caaaacgcag attaaccgaa ctcgtgagcg
    28081 tcgtgttatg agaaaaatca ctgaaaagta cggaccgatt acatataaaa aaggaattta
    28141 actatggaag aaattctctg tattggttgt ggagcaacca ttcagacgac agataaagct
    28201 ggtcttggtt ttacccccca gtcggcactt gaaaaaggtt tggagactgg cgaagtctat
    28261 tgccaacgct gtttccgtct ccgccactac aatgaaatca cagatgtcca gttgacgaac
    28321 gatgatttcc tcaagctctt gcacgaggtg ggagacagtg atgctttagt ggtcaatgtt
    28381 attgatatct ttgattttaa tggatctgtc atcccaggtt taccacgttt cgtctcgggc
    28441 aatgatgtcc tcttggtagg aaataaaaaa gatatccttc ctaagtcagt taagtctggt
    28501 aagattagcc agtggctcat gaaacgtgcc catgaagaag gtcttcgtcc agtcgatgtg
    28561 gtcctaactt cagcacaaaa taaacatgcc attaaggaag tcattgacaa gattgaacac
    28621 taccgtaagg gccgcgatgt ctatgtggtc ggtgtgacca acgttggaaa atcaactcta
    28681 atcaatgcta ttatccaaga aatcacgggt gatcagaatg tcatcactac ttcacgcttc
    28741 ccagggacaa ccttggacaa aatagagatt ccgcttgacg acggatctta tatttacgat
    28801 acgccgggaa ttatccaccg ccaccagatg gctcactact tgacggccaa aaacctcaag
    28861 tatgtcagtc ctaaaaagga aatcaagcct aagacctatc agcttaatcc tgagcaaacc
    28921 ctatttttag gtggtttggg acgctttgac tttatagcag gagaaaagca aggatttact
    28981 gctttctttg ataatgaact caaactccat cgtagcaagc ttgaaggagc tagtgctttc
    29041 tacgataagc acctgggaac tcttctgaca ccaccaaata gcaaggaaaa agaagatttc
    29101 ccaagtctag tccagcatgt ctttaccatt aaagataaga cagacctagt catctcaggc
    29161 ctaggctgga ttcgtgtaac aggcatagca aaagtcgccg tctgggcacc agaaggcgtc
    29221 gccgtcgtca cacgaaaagc aattatttaa aacaaaatcg ctgagcgaac aaagtgagct
    29281 catatagcga tagttattgc cgtggtgtga ttgccaatct gtagattggc aaggggcaca
    29341 attgagacca aggctcaatt gtgaggtcag gaaatccatt tttcaaagat gaaatctttg
    29401 gaaaattagt tccgaccgtc cctcaccacc taaaataact atccaaaaac aaggaagaaa
    29461 attatgtcat taacatcaaa acaacgtgcc ttcctcaaca gccaggcaca caccctcaaa
    29521 cctatcatcc aaatcgggaa aaatggactc aacgaccaaa tcaaaaccag cgtccgtcaa
    29581 gctcttgatg cgcgtgaatt aatcaaggtt actctcttac aaaacacaga tgaaaacatc
    29641 cacgaagtag ctgaaatttt ggaagaagaa atcggtgtgg atacagtcca aaaaatagga
    29701 cgcatcttga ttttgtttaa acaatctagc aagaaagaaa atcgcaagat ttctaagaaa
    29761 gtcaaagaaa tctaagaccg aaactccaaa taactgtttt tatagagaaa taaaggggac
    29821 tagcctatga caatcgaact attgactccc tttaccaagg tagagttgga gccagaaatc
    29881 aaggagaaaa aacgcaaaca agttgggatt ttagggggga attttaaccc tgttcacaat
    29941 gcccatctca ttgttgcgga tcaagtacgg caacagttgg gactggatca agttcttctc
    30001 atgcctgaat accaacctcc tcacgttgat aaaaaggaaa ccatccctga acaccatcgt
    30061 ctcaagatgc ttgagttggc aattgagggg attgacggcc tagtcattga aaccattgag
    30121 ttggagcgca agggtatttc ctacacctac gataccatga agattttgac agagaagaat
    30181 ccagatacgg attattactt tatcatcggt gccgacatgg ttgcctatct gcctaagtgg
    30241 taccgaattg atgaactggt tgacatggtt cagtttgtgg gggttcagcg tccacgctac
    30301 aaggtaggga cttcctatcc agttatctgg gtggacgtac cgctcatgga tatctcgtcc
    30361 agcatggtgc gggacttcct tgcccaaggt cggaaaccca actttctcct acctcagcca
    30421 gtgctagact acatcgagaa ggaggggctc tactgatgtc ctatcaagac tatatcaact
    30481 gctcccgtga ggccttgttg gaaaaaatgg cagagcttct acctgagaaa cgtctaaccc
    30541 attgtctagg tgtggagcgt gccgctatgg aattagctca gcgctttggt gtagatgttg
    30601 agaaagcaag tctagcaggt cttcttcatg actatgctaa aaagttgtca gatcaggaat
    30661 ttctagcctt gattgaccgt taccagctag accctgacct caaaaactgg ggcaataatg
    30721 tctggcatgg tatggtcgga atttacaaaa ttcaggaaga tttggatttg catgattcag
    30781 aaatcctgcg agccattgaa gtccatacag tcggtgctgg tcaaatgaca gacctagata
    30841 aggtcatcta cgtcgcagac tatatcgagc acaatcgagc ctttcctgga gtagatgtgg
    30901 cgcgtgagat tgcaagtcta tcgctcaata aggcggtggc ctacgaaaca gctcgtaccg
    30961 tggagtatct agctcatcag ggattcccca tctatcccca aacccttgaa acctataacg
    31021 cctttgtgca ctatttgaaa gagaactaaa tgaagacggc ttttataatc attgatgttc
    31081 agaatgtttt agtagaaact gggttccaga caaaaagtct attgggaaaa atttcttatt
    31141 tacaaaacca ggctagaagc aagaatattg aaattatcta tgttcaacat attgagaact
    31201 ctgaagctca aacatcagaa gattggcagt tatctgcgct tttaaatcga aaacctgctg
    31261 aaaaggtctt tcagaagaag tataacagta ttttcaaaga aactggctta aaagaatact
    31321 tggataagca ggggattgaa aaattagttt tatgtggtat gcagacagaa tattgtgtgg
    31381 atacctctgt caaggttgcc tttgaatatg gctatcagct tattgttcca gaaggtgctg
    31441 tcacaacctt tgatggggat gacattccag cagaaacgat taatgaattt tatgaggaca
    31501 tttgggagga gcgctttgca gatgtcctag attacaaaca tattttctaa aaagaggatt
    31561 aaatgaacga aaaagaatta ctagaactag tcgtgaaagc ggctgatgag aaacgtgcgg
    31621 aggatatcct cgcacttgat gtacaagatt tgactagtgt gacggactac tttgtcatca
    31681 ctagctcaat gaatagccgt cagttggacg ctatcgcagc taatatccgt gaaaaagtag
    31741 ctcaagcggg ctttaaaggt agccatgtcg aaggcgatgc agctggaggc tgggtcttac
    31801 tggacctcgg tgctgttgtc gtgcatatct tttcagaaga aatgcgtgcc cattataatc
    31861 tagagaagct atggcatgag gcgaattcag tagatatttc agaagctctt gcttagaaga
    31921 tgaactcagt tgtagtcaac tgggtttctt tgcttatttt agaaaaattg atagaaaggt
    31981 aaagggctag tggtgtttac catggagctc ttagtatcat gattatggcg acttatgaaa
    32041 cctttgcggc ggtctatgat gcggtcatgg acgatagttt atacgacaaa tggacaaatt
    32101 tttctctgcg tcatttgcct aagaccaagg agaaaaagaa actcttggaa ctggcttgtg
    32161 ggacaggaat tcaatcagtg cgcttctctc aggctggttt tgatgtgact ggacttgact
    32221 tgagtgcgga tatgttgaag attgcggaga agagagcaac ttcagccaag caaaagattg
    32281 cttttataga aggtaatatg ctgaatttgt ccaaggcagg gaaatacgat tttgtcacgt
    32341 gttattcgga ctctatctgc tatatgcagg atgaggtgga agtaggggac gtctttaagg
    32401 acgtgtacaa tgcgctgaat gaagagggag ttttcatctt tgacgtgcac tcgacctacc
    32461 agacagatga agtattccct ggctattcct accatgaaaa tgcggaagat tttgccatgc
    32521 tttgggatac atatgaggac gaagctcctc actccatcgt gcatgagctg actttcttta
    32581 tcaaggaggc tgacggttcc tttagtcgcc acgatgaagt acatgaggag aggacctatg
    32641 agatcttgac ctatgatatc ttactggaac aggctggatt caagtccttc aaactctatg
    32701 cagactttga ggataaggaa ccaacagaaa ctagcacccg ttggtttttt gtggcgcaga
    32761 agtaggagat tagcatgacc atcacaggta ttatcgcgga gttcaatcct tttcataatg
    32821 gccataaata cctgctggat caggcagagg gactgaaaat tgttgccatg tcagggaatt
    32881 tcatgcagcg tggagagcct gctattgtgg ataagtggac aagggcccag atggcgctgg
    32941 aaaatggcgc agacttggta gtggaattgc cctttttagt cagtgttcag gcagctgatt
    33001 tctttggtca aggagctgtg gatatcttgg atcgcttggg cattgatagt ctagtttttg
    33061 ggacagagga agttcgagat tatcagaaaa tcgctgactt atacacagag aaaggtgctg
    33121 agatggagaa atttgtggaa aatctgcctg attccctttc ctatccccag aaaacccaat
    33181 ctatgtggaa ggaatttgct ggtcttgatt tttcaggtaa tacccccaat catgttcttg
    33241 ctctggccta tgcaaaggcg gttgcaggac gaaatatcaa gctgcatccg attcagcgtc
    33301 agggggcagg ttaccattct gtgaataaag atgtggactt tgcctcggcg acagccctcc
    33361 gtcaacatca gaaggaccaa gatttcttag aacgttttat gccttctgtt gccctatttg
    33421 agcaggccag taaggtgatc tgggaagact attttccctt gctccgctat caaatcttgt
    33481 caaatcccga cctaaccacc atctatcagg tcaatcaaga aatggctgtg cgcattaaag
    33541 aagctattaa aacagcccag tctgtggaag aattggtcga gttagtgact accaaacgtt
    33601 acaccaaggc gcgtgtcaga cgcctattga cctatatttt ggtgcaggct agggaaaatg
    33661 tcttgccaga agccattcat gtccttggat ttactgaaaa aggcaggcaa catctcaagt
    33721 ctctgaaagg acaggtcaat ctagtcagcc gaattggcaa agaaccttgg gatgctatga
    33781 cccaaaaagc agaccagatt taccaactag gaaagccaag tatagcagag caaaattttg
    33841 gaagagtgcc gattagaata gaaacaaact aagtctacta aaaggtaggc tttttgagat
    33901 tttttacgaa taatactctt cgaaaatcaa attcaaatcg cgtcaacgtc gctttgccgt
    33961 actcaagtac agcctgaggc tagtttccta gtttgctctt tgattttcat tgagtataaa
    34021 tagatagaaa agaaaatctt gtacaggttc ctgacaattt ctttcttttc gtgtataata
    34081 gtggaaaaga gctaaaacga ggtatggtta tggaaggagt tctttactca acattccgaa
    34141 atcatttaaa ggattacatg aagaaggtaa atgatgaatt tgagcctttg acggtggtca
    34201 ataaaaatcc agatgaggac attgtagttc tttcaaagag cgaatgggac agtattcagg
    34261 aaaccctgag aatcgcccaa aataaggagt tatcagacaa ggttttgcga ggaatggata
    34321 aaattcgcgc aggacactag tctaatttac agagaatacc tgagtgaaat cttgctgttg
    34381 ttagaaacaa acttcttgta ttgcataatc attaggaagt ctactgcaaa gtaggctttt
    34441 tctcaagtct ctactaaact actatttcta aacaacaagt ttattttggt aaatgtgttc
    34501 caaattcccc aaaacatatt ctattttagg tttgtgaaaa tcactttttt atggtagaat
    34561 gtaaaagaat gtatgtcatt cggaataaca ataaaatgag gtaaaaacat ggaaatcatg
    34621 tcgcttgcga ttgctgtttt tgccgtcatc attggtttag tcattggata tgtcagcatc
    34681 tcagctaaga tgaaatcatc tcaggaagct gcagagttga tgcttttaaa tgctgaacaa
    34741 gaagcaacta atttacgtgg acaagctgag cgtgaagcgg atttacttgt taatgaagcc
    34801 aaacgtgaaa gcaagtctct taaaaaagaa gcactattgg aggccaaaga agaagccaga
    34861 aaataccgtg aagaagtgga cgctgaattc aaatcagaac gtcaagaact caaacaaatc
    34921 gaaagtcgtt tgacagagag agctactagc cttgaccgta aggacgacaa tttgacgagt
    34981 aaagaacaaa cacttgaaca aaaagaacaa agtatttctg atagagcgaa aaaccttgat
    35041 gcgcgtgaag agcaattaga ggaagtcgaa agacaaaaag aagcagaact agagcgtatt
    35101 ggtgctctgt ctcaggcaga agcacgagat attatcttgg ctcagacaga ggaaaacttg
    35161 accagggaga ttgccagtcg cattcgcgaa gctgagcaag aggtcaagga acgttctgac
    35221 aaaatggcca aggacatctt ggttcaagct atgcaacgta tcgctggtga atatgtagcg
    35281 gagtcaacaa actcaacagt tcatctgcca gacgatacta tgaagggacg cattattggt
    35341 cgtgaaggtc gtaacattcg tacctttgaa agtttgacag gggtcgatgt gattatcgac
    35401 gatacaccag aagtggtgac cttgtcagga tttgatccga ttcgtcgtga gattgcccgt
    35461 atgactatgg aaatgttgct caaagatggt cgtatacatc cagctcgtat cgaagagttg
    35521 gttgagaaaa accgtcaaga gattgacaat aagattcgtg aatacggtga ggctgctgcc
    35581 tatgaaattg gtgcgccaaa ccttcatcca gacttgatga agattatggg acgtttgcag
    35641 ttccgtactt catatggaca aaatgttttg cgccattcga ttgaggttgc taagttggct
    35701 ggtatcatgg cgagcgaact tggtgaaaat gcggctcttg cccgtcgtgc tggattcctt
    35761 cacgatatcg ggaaagccat tgaccatgag gttgaaggta gccacgttga aatcggtatg
    35821 gaattggccc gtaagtacaa ggaaccccca gttgtggtga atacgattgc tagtcaccac
    35881 ggagatgttg aagctgagag cgtgatagca gttatcgtcg ctgcagcaga tgccttgagc
    35941 gcagcccgtc caggtgctcg tagtgagtct cttgaaagct acatcaagcg tctccatgat
    36001 ttggaagaaa ttgctaacgg ctttgaagga gtgcaaacta gctttgccct tcaagcagga
    36061 cgtgaaattc gtatcatggt caatccagga aaaatcaagg acgacaaagt cacaatcttg
    36121 gctcacaaag ttcgtaagaa aattgaaaac aatctcgatt atccaggaaa tatcaaggta
    36181 accgtgattc gcgagcttcg tgcagtagat tatgctaaat aaataagaaa gagcagttga
    36241 aaaattactg cttttttgtt acactagata gaaagactgt aaaggataat ctggcttttt
    36301 gccattattc tagagaaatg ttatttcaca gattgactaa aaggagacac aatggcagac
    36361 cgaggcttac taatcgtttt ttctggtcct tcaggggttg gaaaaggaac ggttagaaga
    36421 gagatttttg agagttctga aaaccaattt caatattctg tatcgatgac gacacgcgca
    36481 caacgtcctg gagaagtgga cggtgttgac tatttcttcc gtactcgtga agaatttgaa
    36541 gagctgattc gtcaaggaca gatgttggaa tacgcagaat atgtcggcaa ctactatgga
    36601 actcctctga cctatgtcaa tgaaaccttg gacaagggaa tcgatgtttt ccttgaaatt
    36661 gaagttcagg gtgctcttca ggtcaagaaa aaggttccag atgctgtctt tatcttcctg
    36721 acaccaccag atttggatga attgcaagat cgcttggtag gtcgtggaac agatagtgca
    36781 gaagtgattg cccaacgaat cgaaaaggcc aaggaagaaa ttgccctcat gcgtgagtat
    36841 gattatgcga ttgtcaacga tcaggtgccc ctagctgctg aacgtgtcaa atgtgtgatt
    36901 gaagcagaac acttctgtgt ggatcgtgtc attggtcact atcaggagat gttaccaaaa
    36961 tctccaacta cccgataaaa tttagaaaat aggtacaagc aaatgatgtt aaaaccctct
    37021 attgatacct tgctcgacaa ggttccttca aaatattcac tcgtaatctt ggaagcaaaa
    37081 cgtgcccacg aattggaagc aggtgcccca gcaactcaag gtttcaagtc tgaaaaatca
    37141 actcttcgcg ctttagaaga aatcgaatca ggaaacgtta caattcaccc agatccagaa
    37201 ggaaaacgtg aagcagtgcg tcgccgtatc gaagaagaaa aacgccgcaa agaagaagaa
    37261 gaaaagaaaa tcaaagagca aattgctaaa gaaaaagaag atggtgaaaa aatttaaggt
    37321 tggggggact caatcttatt ttttctattg caagaatgta ctgacaagga ggaggtgaga
    37381 agatggccct agctaagatt atcgtagatg tgcccttgat gcagacggac cagccctata
    37441 gttacaggat tccggaggaa tttgagggaa tgctggaagt tgggatgcgg gttcatgtgc
    37501 cttttggtaa ggggaatcgc ctgattcaag ggattgttct tggtttgaag tcccaatcag
    37561 atggagaaga gatggagcaa gatttaaaag atattgcaga ggtgctggat ttttctcctg
    37621 ttctcacgcc agaacaactc tggctggctg aggagttacg caaatctgtc ttctcctaca
    37681 aaatctctat cctcaaggcc atgcttccag ggtttctgaa ttctagctat gacaagattc
    37741 tctatcctct ggaaggcttg agtcaggaag aacgagtacg cctgtttggt tcagaagatt
    37801 cgctagcctt ttcttcacta gaccttgcca agcaagctga aatgatgcgt ttgactagaa
    37861 aaggcctgct tggtctggaa tatcaggcag tcgatcaaaa gaaggtcaag acccagtctt
    37921 ggtatgaggt tgaccatgcc caattagaag gtgttgagat ttctacacgt gccaagaaaa
    37981 agttggaact gagagattat ctgctgtctc atccagagag cgcttccttg gctagcttgt
    38041 tagagtccta ctcgcgagag caagtcaact tctttgtgga tcaaggtgct gttaccatag
    38101 tccaaaagga agttcaacgc tcggctgctt attttgaagg aattgaagca agtagacctt
    38161 tggagttaaa tccagaacaa agacaggcgc gtgatgcggt tgtgagttct attggcagtt
    38221 ctcaacctcc ctttctactt caagggatta caggaagtgg gaagaccgag gtttacttgc
    38281 agattatcca aggtgccctg gataagggta agacagctat tttgctggta cctgagattt
    38341 ccttgactcc tcagatgacc gagcgtttta tagcacgttt tggggacaag gtagccattc
    38401 ttcactcagg attatccaat ggcgaaaagt atgatgaatg gcgtaaggtg gagcgtggcg
    38461 atgcccaagt tgttgttggt gccagatctg ctatctttgc tcctctgaaa aatctgggtg
    38521 tcatgattat tgatgaagag catgaagcgg cttataagca ggacagcaat ccccgttacc
    38581 atgccagaga ggtagctatt ttacgggctc agtataatca agcaactctg gtacttggat
    38641 ctgcaacgcc gagcttagag agccgggcac gtgctggcaa aggcgtctat cgacacttac
    38701 gtctaaccca acgtgccaat cctttggcta caatccctga ggttcaagtg attgactttc
    38761 gagactatat cggacaaaat gagacgtcaa actttacgcc tcctttgcta gaggctatcc
    38821 aagaccgtct ggttaaaaaa gagcaggtgg ttctcatgct caatcgccgt ggttattcta
    38881 gctttgtcat gtgtcgggag tgtgggacgg tggatacttg tcccaactgc gatatttctc
    38941 tgaccttgca tatggatacc aagactatga actgccatta ttgtggtttc tcgaaggata
    39001 ttcctcaggt ctgtcctaac tgtaagagcc gcagtattcg ttactatggg acgggaactc
    39061 agaaggctta tgatgagcta gcagaactct ttccccaagc tcgcattttg aggatggatg
    39121 tggatacgac tcgaaagaaa ggcagtcacc aagccttgct tgaccagttt gggcgagggg
    39181 aagcggatat tttacttggt actcagatga ttgcaaaggg tttggatttt cccaatgtta
    39241 ccctagtcgg agttctaaat gcggatacgg ccttgaatct gcctgatttc cgttcttctg
    39301 agagaacctt ccagctcttg actcaggtgg caggtcgagc aggtcgggct gaaaaagcag
    39361 gtcaagtctt gatacagtcc tacaattcgc agcactatgc tattcgattt gccaaggatc
    39421 aagattacga aggcttttat gcctatgaaa tgggaatcag acgacaattc ggctatccac
    39481 cttactattt cacgattggt attacccttt ctcacaagaa agaagaagag gttttcaaac
    39541 gtgcctatga agtcatgaac attttgcggt caggcttgtc agagaccagt cccattctgg
    39601 ggccaacgcc aaaaccgatt gcccgtaccc acaacctcta tcattaccag attttaatta
    39661 aataccgttt agaagatgag ctggggccga ccctcaacca ggtcttggcc ttgactcaag
    39721 aacgggaaaa tagtgagctc cgtctcagca ttgaccatga gccgcagcaa tttttataag
    39781 aaggagaaga tatgacaaaa ctaatcttta tggggacccc cgacttttca gcaacagtct
    39841 taaaaggact tttgacagat gaccgttacg aaattctagc cgttgtgacc cagccagacc
    39901 gtgctgttgg tcgtaaaaaa gttatccaag aaaccccagt caagcaggct gccaaggaag
    39961 caggactatc tatctaccaa cctgaaaaat tatctggaag tccagagatg gaagatctta
    40021 tgaagctagg agcagatgga attgtgactg ctgcttttgg gcagtttctc ccaagcaaac
    40081 tccttgatag catggacttt gctgtcaacg ttcatgcctc cctccttcct agacaccgtg
    40141 gtggtgcgcc tatccattat gccttgattc aaggggatga ggaagctggt gtgaccatca
    40201 tggaaatggt taaggaaatg gatgcaggag atatgatttc tcgtcgcagc attccgatca
    40261 cagatgagga caatgttggc accttgtttg aaaaattggc gctagttggt tgtgatttgc
    40321 ttttggacac tctgcctgcc tatattgctg gtgatatcaa acctgaaccg caggatacga
    40381 gtcaggttac cttctctcca aatataaagc caaaggaaga aaaactggac tggaacaaaa
    40441 ccaatcgtca actctttaac caaattcgtg gaatgaaccc ctggcctgtt gcccatactt
    40501 tccttaaggg cgaccgcttt aagatttatg aagccctacc agtagaaggt cagggaaatc
    40561 caggtgagat tctctctatc ggcaagaaag aattgattgt cgcaacggct gaaggggctc
    40621 tatccctcaa acaagtgcag ccagctggta agcctaagat ggacattgct tccttcctca
    40681 atggagttgg acgtacattg actgtaggag aacgatttgg tgactaaagt agaaacggct
    40741 agaagtttag ctctagcagt gctagaggat gtttttgtga atcaagcata ttcaaatatt
    40801 gccttaaata aacacctcaa ggggagtcag ctctctgcag cagacaaggg cttagtgacc
    40861 gagctagtct atggaacggt agcccgtaaa ctgactctgg aatggtacct atcccacttt
    40921 atcgaagaca gagaccagtt agacagctgg ctctatgtcc ttcttctcat gagtgcctac
    40981 caactccgct atttggacaa aattccagat catgctgtgg tcaatgaagc agtggaatta
    41041 gccaaactcc gtaaaaaagg cagtgaaaaa ttggtcaacg ctgtccttcg ccgtatcttg
    41101 cgtgaaggct ggccagatat tgctagcatc aagcgaaaaa acaagcgtga ctccattgcc
    41161 tattctctcc cagtttggct agttgccaaa ctcaaggaag aatacggaga ggagagagca
    41221 aaagccatct ttgaaagcct gttagtgcga aacaaagcca gtattcgtgt aacagaccta
    41281 agtcgaaaag aggaaatcca agccttgttg gaggcgaatg attccctttt agcaaccact
    41341 ggtctggtta aggagcaggg gcattttgca gggcataatt tgtttgcgga tggagccatt
    41401 accatccaag acgagtccag tcagctggtt gctccgacgc ttgatttaca aggtgatgag
    41461 cgagtgcttg atgcctgtgc ggcgccaggt gggaaaacag cccatatagc ctcttatctt
    41521 acgacaggtc aggttactgc tctggacttg tacgaccaca agttggattt aattcaagaa
    41581 aatgcccaac gtctgggagt tgaagatcgg gttcaaactc aaaaattgga tgccagaaag
    41641 gtgcatgagt tttttgacca ggattccttt gataagattt tggtggatgc tccttgttca
    41701 ggaatcggtc ttttgcgccg aaaaccagat atcaaataca ataaagaaac ggcagatttc
    41761 gcgtccttgc aggaaattca gttagaaata ttaggtagtg tttgtcaaat actaggcaaa
    41821 ggtggtataa taacttatag cacctgcact atcgtctcag aggagaattt tcaagtcgtt
    41881 aaggcctttt tagagagtca tcccgagttc gagcaggtaa aactagaaca tgaatgtaag
    41941 gatatcatga aagacggctg tatcctcatt acacctgaat tgtatggaag tgatggattc
    42001 ttcatcagtc aatttcgcaa gatatcggat taggaaggaa ctgacacatg gaaatttcat
    42061 tattaacaga tgttggtcag aaacgaacaa ataaccaaga ctatgtcaac cactatgtca
    42121 atagagctgg acgtaccatg attattttag ctgatgggat gggaggtcat cgtgcaggga
    42181 atatcgctag tgaaatggcg gtcacagacc tgggtgtagc ttgggttgat acccagatcg
    42241 atacagtcaa tgaagtgcgt gaatggttcg cccattacct agaaattgaa aatcaaaaga
    42301 ttcaccagct tggtcaggat gaagcttaca gaggcatggg aactactttg gaagtccttg
    42361 ctattattga taatcaggct atctatgctc atattggtga ttcgcgtatc ggcttgattc
    42421 gtggagaaga ataccatcag ttgacgagcg atcattcctt ggttaatgaa ttgctcaagg
    42481 ctggtcaatt gacaccagaa gaggcagaag ctcatccgca aaaaaatatt atcacccagt
    42541 ctattgggca aaaagatgaa attcagcctg attttgggac agttatcctt gagtcaggtg
    42601 actatctctt gctcaatagt gacggcttga ccaacatgat ttcaggcagt gagattcgtg
    42661 atattgtaac cagtgatatt cctttagcag ataaaacgga gacacttgtt cgttttgcta
    42721 acaatgcagg aggtttagac aacattacgg ttgcccttgt ttctatgaac gaggaggatg
    42781 cagaatgatc caaatcggca agatttttgc cggacgctat cggattgtca aacagattgg
    42841 tcgaggaggt atggcggatg tctacctagc caaagactta atcttagatg gggaagaagt
    42901 ggcagtgaag gttctgagga ccaactacca gacggacccg atagctgtag ctcgttttca
    42961 gcgtgaagcg agagctatgg cagatctaga ccatcctcat atcgttcgga taacagatat
    43021 tggtgaggaa gacggtcaac agtatcttgc aatggagtat gttgctggac tagacctcaa
    43081 acgctatatc aaggaacatt atcctctttc taatgaagaa gcagtccgta tcatgggaca
    43141 aatcctccta gccatgcgtt tggcccatac cagaggaatt gttcacaggg acttgaaacc
    43201 tcaaaatatc cttttgacac cagatgggac tgcaaaggtc acagactttg ggattgctgt
    43261 agcctttgca gagacaagtc tgacccagac taactcgatg ttgggctcag ttcattactt
    43321 gtccccagag caggcgcgtg gttcgaaggc gactgtgcag agtgatatct atgctatggg
    43381 gattattttc tatgagatgt tgacaggcca tatcccttat gacggggata gcgcggtgac
    43441 cattgccctc cagcatttcc agaaacccct gccgtccgtt attgcagaaa atccatctgt
    43501 acctcaggct ttagaaaatg ttattatcaa ggcaactgct aaaaagttga ccaatcgcta
    43561 ccgctcggtt tcagagatgt atgtggactt gtctagtagc ttgtcctaca atcgtagaaa
    43621 tgaaagtaag ttaatctttg atgaaacgag caaggcagat accaagacct tgccgaaggt
    43681 ttctcagagt accttgacat ctattcctaa ggttcaagcg cagacagaac acaaatcaat
    43741 caaaacccca agccaggctg tgacagagga aacttaccaa ccacaagcac cgaaaaaaca
    43801 tagatttaag atgcgttacc tgattttgtt ggccagcctt gtattggtgg cagcttctct
    43861 tatttggata ctatccagaa ctcctgcaac cattgccatt ccagatgtgg caggtcagac
    43921 agttgcagag gccaaggcaa cgctcaaaaa agccaatttt gagattggtg aggagaagac
    43981 agaggctagt gaaaaggtgg aagaagggcg gattatccgt acagatcctg gcgctggaac
    44041 tggtcgaaaa gaaggaacga aaatcaattt ggttgtctca tcaggcaagc aatccttcca
    44101 aattagtaat tatgtcggtc ggaaatcctc tgatgtcatt gcggaattaa aagagaaaaa
    44161 agttccagat aatttgatta aaattgagga agaagagtcc aatgagagtg aggctggaac
    44221 ggtcctgaag caaagtctac cagaaggtac gacctatgac ttgagcaagg caactcaaat
    44281 tgttttgaca gtagctaaaa aagctacgac gattcaatta gggaactata ttggacggaa
    44341 ctctacagaa gtaatctcag aactcaagca gaagaaggtt cctgagaatt tgattaagat
    44401 agaggaagaa gagtccagcg aaagcgaacc aggaacgatt atgaaacaaa gtccaggtgc
    44461 cggaacgacc tatgatgtga gtaaacctat tcaaattgtc ttgacagtag ctaaaaaagt
    44521 tacaagtgtt gccatgccga gttacattgg ttccagcttg gagtttacta agaacaattt
    44581 gattcaaatt gttgggatta aggaagctaa tatagaagtt gtagaagtga cgacagcgcc
    44641 tgcaggtagt gcagaaggca tggttgttga acaaagtcct agagcaggtg aaaaggtaga
    44701 cctcaataag actagagtca agatttcaat ctacaaacct aaaacaactt cagctactcc
    44761 ttaaaagcag atggataatc aagcagatgg ataatcaaaa tgagtaatca atctttgtca
    44821 tgatttcatg gcaaagattt tttttgagtc cggatttgtg atagaataga gggagttgat
    44881 aaaaggagga aagcatggaa gaatcaaaag aattaaatac cgtcattgat gtgattatgc
    44941 tagcggggac tattctcctt aaaagtggct cagaaatcca tcgtgtagaa gataccatga
    45001 ttcgaatcgc gcattcgcag gggattgtgg attgcaatgt ccttgccatg cctgccgcta
    45061 tctttttctc tattgaaaat accaatattt cgcgcatgaa gcgcgtgacc tcctcttctt
    45121 ataacatcga aaaagtctgc gatgtgaacc agatttctcg tcagctggtt ggggggcaga
    45181 ttgatttaga aacagccttt aagcaattga cggccttgca agctcaaccc cttccctata
    45241 ctaagttgca ggtaactctg gctgcgacct ttagcgctcc tttcttttca gttatgttta
    45301 gcggaaatat ctacgacgca cttggggcag gagtggcgac cttatttggt tttgcctttt
    45361 ccctctatgt ggaaaaattt atccgaattc cctttgtgac agcctttgct ggagcctttg
    45421 tctttgggat aattgcccag ttttgggctc gctacacagg ttttccttca acggcagatt
    45481 tgattatagc tggtgcggtc atgccgtttg taccaggtat tgccttgacc aatgcggtcc
    45541 gtgatattat gaccaaccac ataaactctg gtatgagtaa gatgtttgaa tccctgctca
    45601 ttaccctcgc tttaggggca ggaacttctg tcgccttggt attgatgaac taatatgaca
    45661 ctaacaacct ttttattaca agcagtagca agttttcttg ccattatcac ttttttaatc
    45721 gtactcaatg tgcaacggtc tatgctctta cctggaggga ttttgggcat gactgtctgg
    45781 ctaatctatc tcttgctcaa ggagccgacc aatgtcattg tagctacctt cattgcagcc
    45841 attattggtt cttgtgtcag ccagatttta agtattcttt ataagacacc tgctgtggtc
    45901 tttatcttgg ccattttggc accgctggtt ccaggttatc tctcctaccg aacaactgcc
    45961 ttttttgtga caggggacta taataaagca ctggcaagtg cgaccttggt tgtcatgttg
    46021 gctttggtaa tctctattgg aatggctagc ggaacagtga ttctcagact gtatcattat
    46081 ataaaaacac atcgagtatc gtagacttta cacaaatgaa agaattttct gaaaaatgag
    46141 ataaataaat taacaacgct ttctatatgt gcgagaatac cgcacttatg aagaaattgc
    46201 ggctgatttt ggtatccacg aaagcaactt aatccgtcgg agccaatggg ttgaagtaac
    46261 tcttgttcaa agtggtttta cgatttcaag aactcctctc agttctgagg acacggtaat
    46321 gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa gaattagcga atgattctgg
    46381 taaaaagaaa tgccacgcta tgaaggctca agcgattgtc acaagtcaag ggagaattgt
    46441 ttctttggat atcgctgtga actattgtca tgatatgaag ttgttcaaaa tgagtcgcag
    46501 aaatatcgga caagctggta aaatcttgtc tgacagtggt tatcaagggc tcatgaagat
    46561 atatcctcaa gtacaaactc cacgtaaatc cagcaaactc aagccgctaa cagctgaaga
    46621 taaagcttgt aaccatgcgc tatccaagga gagaagcaag gttgagaaca tctttgccaa
    46681 agtaaaaacg tttaaaatgt tttcaacaat ctatcgaaat catcgtaaac gcttcggatt
    46741 acgaatgaat ttgattgctg gcattatcaa tcatgaacta ggattctagt tttgcaggaa
    46801 gtctactatt ttccttattg tctgtaagtc tactgacctt gttgtttatc ccagtcatgg
    46861 tttctagttg gggctcagag tttcaaagtg gatggcaaga gcatcaattg attgctgaga
    46921 aggttagtaa aacacttgac aagacatttg ataaggatgt cagagaaatt ccgaccagtc
    46981 agttttatca aaaatttgta gatgagatgg gaaggactta ctcaggaaat ttgatcctcc
    47041 aggagctgat aactgtgaat ggagcttata aagctactta tatcggtgaa ctctctagca
    47101 actaatcatt ctttaaaatg atgaccaata agaggcttga tttggtgaat caagtctttt
    47161 ttctctcttt tactgccatt tgtgataaaa tagtatagaa cgatttttta catgaatgat
    47221 aaaacagagg taaatatgac aatcggtatt gataagattg gttttgcgac cagtcaatat
    47281 gtcttgaaat tacaagactt agcagaagcg aggggaattg accctgaaaa attaagtaaa
    47341 ggactcttac tcaaggaatt gagtattgcg cccctaactg aggacatcgt gaccttggcg
    47401 gccagtgcta gtgactctat tttaactgag caagaaagac aagaagttga catggtcatt
    47461 gtggctaccg agtcaggaat tgaccagagt aaggctgcgg ccgtctttgt gcatggcttg
    47521 ctgggcatcc agccctttgc tcgtagtttc gagattaaag aagcctgcta tggggcgaca
    47581 gctgccctcc attatgccaa attgcatgtg gaaaattctc cggagtccaa ggtcttggtc
    47641 attgccagtg atattgccaa atatggtatt gaaactccgg gagaaccaac tcaaggtgct
    47701 ggaagtgtgg ctatgttgat tacacaaaat ccacgcatga tggcctttaa taatgacaat
    47761 gtagctcaga cccgtgacat catggatttc tggcgaccaa attactcgac aactccttat
    47821 gtaaatggtg tctattctac ccaacaatac ttggatagtt tgaaaacgac ttggcttgaa
    47881 tatcaaaaac gctaccagct tactttggat gattttgcgg ctgtttgttt ccacttgcct
    47941 tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg ataagagcct gcctcaagag
    48001 aaaaaagacc tcttacaaaa gcattttgac cagtctattc tctacagtca aaaggtgggg
    48061 aatatctaca caggttcact tttccttgga cttttgtctc tcttggaaaa tacagatagc
    48121 ttgaaagctg gggataaaat cgccctttat agttacggaa gtggagctgt ggctgagttc
    48181 ttcagtggtg aattggttga aggatatgaa gcttatttgg ataaagaccg tttgaacaag
    48241 ctcaaccaac gaactgccct atccgttgca gactatgaaa aggtcttttt tgaggaagta
    48301 aacttggatg aaacaaactc tgcccagttt gctggctatg aaaatcaaga ttttgccttg
    48361 gttgaaattc tcgaccacca acgccgttat agcaaggttg aaaaataatg aagataagtt
    48421 ggaatggatt ttctaaaaaa tcataccaag agcgcctcga gctgttaaaa gctcaggcgc
    48481 tccttagtcc tgagagacaa gctagtctgg agaaggatga acagatgagc gtgactgtgg
    48541 cagaccagct gagtgagaat gtagtgggaa ctttttctct gccttattca ctggttccgg
    48601 aggtacttgt caacggtcag gaatacaccg ttccctatgt gacagaagaa ccctctgtgg
    48661 ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc aggtggtttt actgcacaag
    48721 tccatcagcg ccagatgatt gggcaggtag ccctttatca agttgctaat cctaaactag
    48781 cgcaagagaa gattgccagc aagaaagcgg agctcttgga gcttgccaat caagcctatc
    48841 cttctatcgt taaacgtggg ggtggggcgc gtgatctgca tgtcgagcag ataaaaggcg
    48901 aaccagactt tctcgttgtt tatattcatg tcgataccca ggaagccatg ggtgccaata
    48961 tgctcaacac catgctggaa gccttgaaac cagtcttaga agaactcagt cagggacaga
    49021 gtctcatggg aatcctgtcc aactacgcga ctgattctct ggtgactgca agctgtcgca
    49081 tcgcctttcg ctacttgagc cgccaaaagg atcaaggacg agagattgcg gagaaaattg
    49141 cgttggctag tcagtttgcg caggctgatc cttaccgagc tgctactcat aataaaggaa
    49201 tttttaatgg tattgatgcg attttgattg ccactggtaa tgactggcgt gccatcgaag
    49261 ctggggccca tgcctttgcc agtcgagatg gacgctatca aggtcttagc tgctggacgc
    49321 tggaccttga aagagaagaa ttggtcggtg agatgaccct gcccatgcct gtagcgacta
    49381 agggtggctc tatcggcctc aacccacgtg tagctctcag tcatgatcta ctaggaaatc
    49441 cttctgccag agaattagcc cagattatcg tgtccatcgg tcttgctcaa aattttgcag
    49501 ccctcaaagc cttggtaagt acgggcatcc agcaaggcca catgaaacta caggccaaat
    49561 ccctagctct cctagctggg gctagtgaat ctgaagttgc tcccctagta gagcgcctca
    49621 tctcagataa aacctttaac ctagagacag cccagcgcta tctcgaaaat ttaagatcat
    49681 aaaaactcag acgaatcggt ctgagttttc ttgtgtttaa atactttttc ctggtaatag
    49741 cgtaactggt aagaagtaac cagttgtggc gacttccttg ccttcaatct tttgcaagag
    49801 aagatcaata gtgagacaag caatctcttc caaaggttgc ttgatagtag ccaattgagg
    49861 gtagtaattt tcgataaagt aggtcccatc atagccgatg accttgagct cttttgggac
    49921 agaaatgccc aattcttgag cgattttaat gaccagaata gctgtcaaat catccgaagc
    49981 aaaaatggca tctggttttt cccgggtcaa gatattcttg atttccattt cttttctgac
    50041 gggagaaaag tcactggaaa cattgataat aggagctttt gggagtacgg atgcaaaacc
    50101 agcgtggcgc agtccggttg gcgaattgga attgtcattc cctgtaatca tgatgataga
    50161 ctgggcacct gtcttgacca aggtttgggc agcaagaacc ccaccagcat agttgtcaga
    50221 ggagacaaca gggatgtctg gcgataggtt tcggtcaaag gaaataatcg gcgctgtcac
    50281 acgattgtag tcttcgattc ctaggttgtg actaccagaa atgatgccgt ctacctgatt
    50341 ggcttccaac atttcgatgt attcgcgttc cttctcagaa tcatgttcac tgttgcagat
    50401 gatggtcttg taaccatttt tgaagagttg gtgttccaat ttatcaatca attctgcata
    50461 gaaaacattg gaaatattgg ggaaaatcaa gccgattaac ttagctgatt ttccttgcag
    50521 actacgagcc aggttgttgg gtttatagcc taattctctc atggcttcat tgactttttg
    50581 gatggttttc tcagatagat atcctttttt attgataacc cgagaaacgg tagtaggact
    50641 gacgcctgca agtttggcga catcagttag ttttgcgacc ataatctaat tcatagtaag
    50701 ttccagttgg gtttccagat ttgatcagga taccattttg gtccgcatgt gggaagacac
    50761 gaccagaaaa tactttttct cctttattga tgaaaatttc aaagacagag ttatcgatga
    50821 agattgtagc agtagtagcc tgattctcga tagggcaaga acgagttgtc ccaaattctt
    50881 gggcatactg ttctccagcc tggctacgat ccactgtcac ttgaccgttt acaaggtcaa
    50941 agttgattga aagtccctta ccttctttat cagcaagtaa gacaatctcg ctctggctat
    51001 tagcttccaa gttgagttca agttcgtaag tgttcttggt ttgggaacgg tttgagaagg
    51061 cttcttcaga agcacgaagg tccttaatag cagcgactgg atactggtag agcttgtcgt
    51121 ctttgatagt gagttccttg accaaagaga aggttccttg gtggtcaaaa cggtcagatg
    51181 ggtaagaaac atctggcaaa ccaagccagc taactgctag agcacgccca tcaggagcgt
    51241 tgaaggcttg agttgcatag gcttcgaaac cgtaatccat gttttgaagt tgagacacat
    51301 ctaccatttt ggcattttta gggtcaaagg aagccccaat cttatacata tttggaaaga
    51361 tattatcgta gtctagaact ttcttatcca atccttgtgg acagtagaga aggacaggat
    51421 gttcctctac aaagaccaga ttaggacatt ccatcatgta ggcagtacgg tcgttagcaa
    51481 agtcaaggtc gccaactgct tgccagtttg tgtagtcgtt attgacagcc ttgtagagac
    51541 ggacgaagcc ttttttctcc aagtcctgtc caccgacgac agcatagtat tgacctttaa
    51601 agttaaaaat ttgtggatcg cggaagtggt cagtagagtc tgctggctgg tcaatcaaga
    51661 tcttgtcaat ctttgtaatc ttaccctcct tgtccatcaa agcaccgatc tggtatgggt
    51721 gacggatcca gttttcatcg cgaacatttc ctgtataaaa taggaataag ttatcgccaa
    51781 attgcatggc agaaccagag taggcaccgt ggctatctaa tggagtatct ggtaaaactt
    51841 tgattccagt ttctttaaag tgaaccaaat catcactttc tagctgtgcc caagatttca
    51901 aaccgtgggc tgcaccaaaa ggaaaattct ggtaaaagag gatccacttg ccatcaaagt
    51961 aagaaaagcc atttgggtcg ttgagaagtc ctgtttttgg ctcaacatgg taatgagtat
    52021 gccatggaga ttgtgccata ttttccttta tatgttgaat ttcttcttgc gtccaatctt
    52081 gataaagtct gtaacgacgc tcagttgtcc attccattca ttcctccaaa aatcttatca
    52141 cttttaatag taactgtttt cgataaaaaa tgcaagcctt ttatgttaaa aaagaggaaa
    52201 aactgtcaaa cgattatcat aaaataaata caggaaatca atcaaatttt tacgaaaatg
    52261 tgaaagataa tgaaataaaa gactttttaa ccaaggtttc aaacttattt ttcaaggaat
    52321 tcctgatgaa acagtcaaaa acaatcaatc taaaacttgc ccactaagtg gatagaatat
    52381 tttttctgca aaacgcttga catattttta aaacatgata aaataatagt cgtaagggcg
    52441 aataaaatcg ctttcaaaca agaacaaaat gttatataag gagatttttg caaatgaaca
    52501 atcaggaaat tgcaaaaaaa gtcatcgatg ccttgggcgg acgtgaaaat gtcaatagtg
    52561 ttgcccactg tgcgactcgt ctacgtgtca tggtcaaaga tgaagagaaa atcaataaag
    52621 aagtgattga gaacttggaa aaagttcaag gtgctttctt taactcaggg caataccaaa
    52681 ttatctttgg tacaggtaca gttaacaaaa tgtacgatga agttgttgta cttggcttac
    52741 caacatcatc taaggatgac atgaaagcag aagttgctaa acaagggaac tggttccaac
    52801 gtgctatccg tactttcggt gatgttttcg ttccaatcat cccagttatc gtagcgacag
    52861 gtctcttcat gggtgtgcgt ggtcttttca acgctcttga aatgccactt ccaggtgact
    52921 ttgcaactta cacacaaatc ttgacagata cagccttcat catcttgcca ggtttggttg
    52981 tgtggtcaac cttccgtgta tttggtggaa atcctgccgt tggtatcgtt cttggtatga
    53041 tgcttgtctc tggctcactt ccaaacgctt gggcagttgc tcaaggtggt gaagtaacag
    53101 cgatgaactt ctttggtttc atccctgttg ttggtttgca aggttccgtt cttccagcct
    53161 tcatcatcgg ggttgtcgga gctaaatttg aaaaagctgt ccgcaaggtt gttccagatg
    53221 tcattgacct cttggtaaca ccattcgtga cacttttggt catgtctatc cttggactct
    53281 ttgtcattgg accagttttc cacgttgttg aaaactacat ccttattgct acaaaagcga
    53341 ttcttagcat gccatttggt cttggtggtt tcttgattgg tggggttcac caattgatcg
    53401 tcgtgtcagg tgtgcaccac atcttcaact tgcttgaagt gcaattactt gctgctgacc
    53461 atgctaaccc attcaacgct atcatcacag ctgctatgac agctcaaggt gctgctactg
    53521 ttgcggttgg tgttaaaaca aaaaatccaa aactgaaaac acttgctttc ccggctgctc
    53581 tttctgcctt cctaggtatt acagagcctg ctatcttcgg ggtgaacttg cgcttccgta
    53641 aaccattctt cctttcattg attgctggtg caatcggtgg tggattggct tctatccttg
    53701 gacttgctgg tactggtaat ggtatcacca tcatccctgg tacaatgctt tatgttggta
    53761 acggacaact tccacaatac cttcttatgg tagctgtatc atttgccctt ggttttgctc
    53821 ttacttacat gtttggttac gaagatgaag tagacgcaac tgcagctgca aaacaagctg
    53881 aagtggctga agaaaaagaa gaagttgcgc cagcagctct tcaaaatgaa acacttgtaa
    53941 ctcctatcgt cggtgatgtt gtcgctcttg ctgatgtcaa tgacccagtc ttctcaagtg
    54001 gagctatggg acaaggtatc gctgtgaaac caagtcaagg cgtggtctat gcactagctg
    54061 atgctgaagt ttcaattgcc tttccaacag ggcacgcttt tggtttgaaa acaagaaatg
    54121 gtgctgaagt tttgattcac gttggtattg acactgtatc tatgaacggt gacggttttg
    54181 aagcaaaagt tgctcaaggt aataaggtga aagctggcga tgttcttgga acatttgact
    54241 caaacaaaat cgctgcagct ggacttgatg atacaacaat ggttatcgtt acaaatacag
    54301 ctgactacgc ttcagtagct ccagtcgcaa caggttcagt ttcgaagggg gatgctgtga
    54361 tcgaagtgaa aatctaatca atcctctcta atgtgaaaac gaacaaatga catgtttgtt
    54421 cgtttttatt agatagtaag atttacagag gaaaatctaa aaaatagaga catttagact
    54481 ttcgaagtat gctataataa agaaaataaa aacaagaggt ttatcatgac aaaattatat
    54541 ggaagcttgg aagcgggcgg tacaaagttt gtctgtgctg tcggtgatga aaactttaac
    54601 gttgtagaaa aaacacaatt tccaacaaca actccaatcg aaacaatcga taaaaccatt
    54661 gagttcttct caaaattcga taaccttgct ggtcttgcag ttggttcatt tgggccgatt
    54721 gatattgaca aaaactcaaa aacttatggc tttatcacga cgactccaaa accaaactgg
    54781 gcaaatgtag acttgcttgg tgcccttcgt cgcgccctaa acgtgccaat gtacttcaca
    54841 acagacgtaa acagctctgc ttacggtgaa atggttgccc gtaacaatgc tggtggtcgt
    54901 atcgaaaact tggtttacta cacaatcggt acaggtatcg gtgcaggcgt catccaacgt
    54961 ggtgagttta tcggtggtgt gggtcaccct gaaatgggtc attattatgt tgctagacac
    55021 ccaatggata ttgaaaaaga gtttaagggt gtttgtcctt tccataaggg atgtctagaa
    55081 ggttatgcag ctggtccaag tttggaagct cgtacaggtg tacgtgggga aaatattgaa
    55141 ctcaacaacc ctgtttggga tgttcaagcc tactatatcg ctcaagctgc ggttaatgcg
    55201 acagtgactt tccgcccaga cgtgattgtc tttggtggag gggtcatggc tcaacaacat
    55261 atgctggacc gtgtccgtga gaaatttaca tctcttctta atggttacct accagtacca
    55321 gatgtgcgtg actatatcgt gacgccagca gtcgcaggaa atggttctgc cacacttggg
    55381 aactttgttc ttgcaaaaga agtttcaaaa taaagcacaa aatccgcttg ggaaaccaaa
    55441 cggattttgt ggttgaaaac aatatttttg agcctttcct taagtgatta cggacggtag
    55501 cgactttctt cgaaattcca tacctaaact ttgagcctag tgtctcaaag tttccgaata
    55561 cctgaaacca ttagatttca ggtgtttcta tcacggcgga aaggctaggt aagtcctcgc
    55621 ctcactatcg aaaaatatgc ataatttcca taccaaagta tatttagtat caagctatag
    55681 ttaatctacg ctttaaaaat ccacttggga aaccaaacgg attttttacg tgtcaaagca
    55741 tttgccagaa aaagtcaata atataggtca aaccgtaggt ataaaccacg agggtaaagg
    55801 gtttggtcag aatgatgatg gtcatgtagc gcttgaaact catcttggtc agggcagcca
    55861 gcatacagag aaagtcagct gggctaatgg gccaaatcat cataaaaata aagaagcggt
    55921 caaaacgatt gcccttatct agccagccga tgtacttgtc gtaggtgcgc ttgctgacga
    55981 cagactggac aaaggcagct ccgtataggc gcactagata aaagataatg gcacagccaa
    56041 tcacgatgcc gatatagttg tagatagtcc cgatgatgtg cccgtagata aagaccccag
    56101 ccaccgaggt caaggcccct ggaatgatag ggacgacagt ctgtaaaatc tgtaaaaaga
    56161 taaagagagg tggaccccag atgcctgcct gctggataaa ggcagagagg gtttccttgg
    56221 attgtaaaat cccagcctga taagcccaaa tacagaaaat caaactccca accccaccga
    56281 caatcgatga gatattgata actcgctgca gaaggggaga aacagctttc atttgtttat
    56341 cctgtgacat gtaaactcct catagatagt atatttctac tataccatat tttggaggag
    56401 aaagggggaa tgagtctttt ttgataagga atagaaagta aatagccctt cgagacttag
    56461 aataggtctg tcaactaaag gttatatgca ttctaggttt cgaataatcg caattccata
    56521 aatttaaaag cattctaagt ttcgaatagc ttatctgaga taattttgag gcattcgcgc
    56581 tttcgaatag tcattttccc taaagtttag atgtattctg aagctagaaa gactaaaatc
    56641 taaaagtagt aagagtctct ctctgatgga cgtaatttat ggctagtatg aatcctttga
    56701 attgttagtt aattttaata ttaatcagtt ctgaaataat tactaaatat agttagatgg
    56761 tgaattaatt attgctaaat ttcaagttca agttagtcat ccagaagtct tctctggggg
    56821 acttgtagtt caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
    56881 cctttgtagt cgttttctta gttccctgag gtaaccatct atgaatgaac ttgttgtgat
    56941 ttttattaga tcctatagtg gtgtgcataa tagatatagc agattgaaac tagaatagta
    57001 tacatctact tctaaaacat tgttagaaat cgatttgact gtcccgatct atttgtcctg
    57061 tttttatttc attttactat ataatcctta gaaaatatat cggacaagcg gttgaattcc
    57121 gttccgtcca ttagtagata aaggattact ccttcttgaa atgacagatg aacttgtttc
    57181 ttataaaaat gttgtctgaa actattcgct tttttccaga agttttagag gaagaaaact
    57241 ttatgaggaa aaaggagtta ctcaaataac aattcaggat taaaaataga cagttgagga
    57301 gcggaaggta taaattgagt ttgctactgt ataatggatt tatcactaat actcttcgaa
    57361 aatctcttca aaccacgtta gcttcgcctt gccgtagata tagttactga cttcgtcagt
    57421 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttttat ctgcaacctc
    57481 aaagctgtac tttgagcagc ctacggctag cttcctagtt cgctctttgc ttttcattga
    57541 gtataaaagt gctccaggcc atattttaca cagcaatagt cttctaaaaa tggacaaaaa
    57601 cattgtaaag gctatcaaaa aggagtataa tgagtgcaag aaatttcgga ggtgaaagat
    57661 gctagaagta agaagtctag agaaaagttt tggctccaag caagttttgt ttggtattga
    57721 ctttcaagcg cgaccaggtc gtattttggg actagtcgga aaaaatggtg ctggaaaaac
    57781 aacgattttc catagtattt tgaaattcct agaatatcag ggagaaatcg gtctggatgg
    57841 tcaggatatt cgtcaggaga cctatgctcg gattggttat ctgcctgaag aacgcagtct
    57901 catgcctaaa ttgacagttc ttgaacaagt tcgctacttg gcgactctaa aaggcatgga
    57961 tgccaaagaa gtcaaagaaa aactccctca atggatgaag aggttggaag tgaaaggaaa
    58021 gctgacagat aaaatcaaga gtctgtcaaa aggaaatcag cagaagattc agctcattat
    58081 tactctgatt catgaaccag acctgattat cttggatgag ccttttagtg gattggaccc
    58141 agttaataca gaattgctca aacaagtcat ttttcaggaa aaagagcgcg gagcaaccat
    58201 tatcttttct gaccatgtca tgaccaatgt tgaggaactt tgtgacgata ttctgatgat
    58261 ccgagatggc cgtgtggtct tgcacggacc agttcaggat gtccgcaatc aatacgggaa
    58321 aacgcgtctc tttgtttcaa gtgaacgaag caaggaagaa ttggaaaatc ttcctcatgt
    58381 caaacaggtg agcttgacca aacaaggcag ttggaaattg attttggagg atgagagcgc
    58441 tggaagggaa ctcttcccaa tcttgactca aggtcaatat atcgcaacat ttgaccaaca
    58501 agcgccaact atcgatgaaa tctttaaact agaatcagga gtggaagtat gagaaatatg
    58561 tgggttgtaa tcaaggaaac ctatcttcga catgtcgagt catggagttt cttctttatg
    58621 gtgatttcgc cgttcctctt tttaggaatc tctgtaggaa ttgggcatat ccaaggttct
    58681 tctatggcta aaaataataa agtggcagta gtgacaacag tgccatctgt agcagaagga
    58741 ctgaagaatg taaatggtgt taacttcgac tataaagacg aagcaagtgc caaagaagca
    58801 attaaagaag aaaaattaaa aggttatttg accattgatc aagaagatag tgttctaaag
    58861 gcagtttatc atggcgaaac atcgcttgaa aatggaatta aatttgaggt tacaggtaca
    58921 ctcaatgaac tgcaaaatca gcttaatcgt tcaactgctt ccttgtctca agagcaggaa
    58981 aaacgcttag cgcagacaat tcaattcaca gaaaagattg atgaagccaa ggaaaataaa
    59041 aagtttattc aaacaattgc agcaggtgcc ttaggattct ttctttatat gattctgatt
    59101 acctatgcgg gtgtaacagc tcaggaagtt gccagtgaaa aaggcaccaa aattatggaa
    59161 gtcgtttttt ctagcataag ggcaagtcac tatttctatg cgcggatgat ggctctgttt
    59221 ctagtgattt taacgcatat tgggatctat gttgtaggtg gtctggctgc cgttttgctc
    59281 tttaaagatt tgccattctt ggctcagtct ggtattttgg atcacttggg agatgctatc
    59341 tcactgaata ccttgctctt tattttgatc agtcttttca tgtacgtagt cttggcagcc
    59401 ttcctaggat ctatggtttc tcgtcctgag gactcaggga aagccttgtc gcctttgatg
    59461 attttgatta tgggtggttt ttttggagtg acagctctag gtgcagctgg tgacaatctc
    59521 ctcttgaaga ttggttctta tattcccttt atttcgacct tctttatgcc gtttcgaacg
    59581 attaatggct atgcgggggg agcagaagca tggatttcac ttgctattac agtgattttt
    59641 gcggtggtag caacaggatt tatcggacgc atgtatgcta gtctcgttct tcaaacggat
    59701 gatttaggga tttggaaaac ctttaaacgt gccttatctt ataaatagaa gagccttgcg
    59761 aaagcgaggt ttttaaaggt gaaaagggtg gaatcacgaa cctaattatg tacacattat
    59821 gtaaacaggt tgcttgaaaa ctcaattgta tagtgaactg aatctggaat aggataatat
    59881 tacttctaaa acattcttat aaattgattt gaattccaaa atcccatcgt tccgttctta
    59941 tttcattttg cgatatagcg aaaggaaata agtcagctca caaaaaacgc ataatatcaa
    60001 ggatttttaa cacttgatac tatgcgtttt ctaattttaa agactttttg cctggtctct
    60061 tttgttctat gagtatgtta catatctagg taaaaattat ttaaagcaaa ttaaccttat
    60121 ttctcaagat gtagtaggtt ccgagataaa agatagctat gaatatgagt tctttaacaa
    60181 tggctatacc tgctcccata tagaaatggt cattgagtcc taccagtgaa ttgacataga
    60241 aattggaact aagattgaag aaaagttcaa taaatccaat gacgatttgg ataccaatgt
    60301 aggctgcaac agcgagtgct gtacggtatt cattgaaaag ctgtccaatg gaaatagcca
    60361 ggtagatgca gaggattcct gaaatggtat ttagtaggaa ggatatacct gtaagaaaga
    60421 tctgagggag atgtgtttct acaaatgtaa tcacataaga aagaggaatc cattctggag
    60481 ctgttaaagc cagaataata acagcactta gagccaatac agcggtgcta atcaatgacc
    60541 agataaaggc accgattagt ttggctgtga tgatatggtg ttcagaaact ggcaaggtca
    60601 aagtcagata gccttgtcgg tcgtagacac tacctttgaa gcgtttaata atcaagaaaa
    60661 tggttgaaat cgcaagtgta agcatcaagc caccaaagac tgtagctaga aaaagtagca
    60721 tagtagcctg actttcttgg taaggtagat ttttaaagcc ttgtgtctgt attccgatga
    60781 gggcagaaag gactagcacg gctgcgtaga gggctaaata ccacttgtta acatttttaa
    60841 attcgtagtg aactaaattc caaaacataa ataatctcct ttgcttaggc cttaaattcc
    60901 tgacggaaga gttggtcaat ggattcacct gactcgtagc gaatatcatc tacatttcct
    60961 tgacggacga cttttccgtc ttttaggaag acaatttcat ccaagattgg ctcgatatca
    61021 gaaatcaagt gggtagaaat caaaacggta gaagttggtg agtagttgtt gataatggta
    61081 ttgaggatat aagcacgggc tgctggatcc accccaccaa tgggttcatc caaaacatag
    61141 agacgagcat cacggctcat aaccaaaatc agttgaacct tttctttgtt tccttttgat
    61201 agtttcttga gacgactatt ttcatcaatg cccaggtctg caagtagatg atgggcgcgt
    61261 tcaagattga aatctttata gaaggtcttg aagtaggtta gggcttcttt gaccttcatt
    61321 tgctcattga gataggtcgt atcaggcaaa taagctacaa cggccttggt tgctgggctt
    61381 gggtccatgt cgttgatgag gacacgtcct tgatctggtt gtaagaggcc attaattagt
    61441 ttaatcaggg ttgtttttcc tgagccgttt ggcccaagaa ggccgacaat ttttccagct
    61501 ggaatgtcaa gagaaacatt ttcaagggct ggtgttgctc catatgattt ggatacattt
    61561 tcaaatgcta gtaatgacat aggcttaaac tcctttaata taatcactga ctacgcctgg
    61621 tagttcttct ttttcatagc caaaatgggt catggaggaa acgaagtgtt ccaattcttc
    61681 ttctgataat tgtttgcgtg actgagcgat tagctcctta tccttagtca caaatcgtcc
    61741 agttgttcgc ttgctgtaga caaatccttc tcgttcaagg tctgataagg ctctttggat
    61801 ggtattggga ttgacaccag cctcgctagc tagctccctc acggttggaa gttgttgatt
    61861 gggttccagt gtatgggaaa caatctgaag cttgattttc tccataatct gtaaatagat
    61921 gggttttttg ttgtcaaatg tccaggacat cttagtctcc tttcttttac ccttttgtct
    61981 taattaaata atacaacaaa acaaaaaact tgtcaagcaa aaagaagaat tgttttggga
    62041 atcgcttaaa aaatggtata atgaaaagaa aacgataagg agggaaagga tgcgttgtcc
    62101 aaaatgtggg gctaccaagt caagtgttat cgatagtcgc caagcagaag aagggaacac
    62161 cattcgtaga agacgtgagt gcgacgaatg ccaacaccgt tttacaacct acgaacgagt
    62221 agaagaaaga accttagtgg ttgttaaaaa agatggcaca cgggaacaat tctccagaga
    62281 taaaatcttt aatgggatta tccgctcagc ccagaaacgt cctgtgtcaa gtgatgaaat
    62341 caacatggta gtcaatcgta tcgaacagaa actccgtggt cgaaatgaaa atgaaattca
    62401 aagtgaggac attggttcac tcgtcatgga ggagttggct gaattggacg agattaccta
    62461 tgtacgtttt gctagtgtct atcgtagttt taaggatgtc agtgagttag agagcttgct
    62521 ccaacaaatc acccagtcct ctaaaaagaa aaaggaaaga taaatgaagc caattgaccg
    62581 tttttcttat ctaaagaata atcgggtgtc gcaagatacc tcatctctgg tacagtgcta
    62641 cctcccgatt atcggtcagg aggcactgag cctttatctt tatacaatca gtttttggga
    62701 taatggtaga aaggaatatc ttttttcaag cattctcaac catcttaact ttgggatgga
    62761 tagactgata aaatcattga aaatcttatc tgcttttaat ctcttgaccc tctatcaaaa
    62821 gggggatgtt tatcagctag tcctccatgc tcctctatct agtcaagact tcttggagca
    62881 tcctgtttat cgcagactct tagagaaaaa gattggcgat gtagctgtgg aggatttgaa
    62941 agttgaaagt gctgatggtg aagaaatacc tgtctcactc aatcaagtct ttccagaatt
    63001 ggcagaacta ggcagtcaag aagaccttgg tctcaagaag aaagtggcca acgattttga
    63061 cttggaccat tttcgccagc tgatggctcg agatggactt cgttttgcgg atgagcagtc
    63121 cgatgtctta aacctctttg ctattgccga ggagaagaaa tggacttggt ttgaaaccta
    63181 tcaattggcc aagtcaacag ctgtttctca ggttatttca accaaacgca tgcgggaaaa
    63241 aattgctcaa aaaccagttt cctctgactt tagtcttaag gaaacaacca ttatcaaaga
    63301 agccaaaagt aaaactgccc tgcagttctt ggcagaaatc aagcaaacac gcaagggaac
    63361 cattacccaa acagaaagag aactcttgca acagatggct ggcttgggct tgctggacga
    63421 agtcatcaat atcattcttt tattgacctt taataaggtc gattcggcaa atatcaatga
    63481 gaaatatgcc atgaaggtag ccaatgacta tgcctatcaa aagattcatt cggcagaaaa
    63541 ggcagtcttg cgcatccgtg agcgagaaca gaaagcaaaa acacaaaaac agaatcagac
    63601 tgccccagca aaaaccaata ttcctaaatg gagtaatcct gaatataaaa atacgtcatc
    63661 cgctgaggaa ttagaagaga tggaacgcca aaccctagaa ttattagcaa aattagataa
    63721 cggaggtgat tagatggaaa gtgtcggaga tgtactcaaa cgtcaaccaa gtcgttttca
    63781 ctatcaagat ttagttcaga aaatcatgaa ggatcctgat gttgcggcct ttgtccagca
    63841 agaatccctc aatcaggacg agttgaaccg tagtatttcc aagtttaacc aatacatcac
    63901 tgagagagat aaattcctcc gaggagatac agattatatt gccaaaggct acaagcctat
    63961 attagtcatg aaccatggct atgcagatgt ttcttatgaa gaaactcctg aactaatcgc
    64021 agctgaaaaa gaagcggcta tcaagaaacg tctcaactta attaattttc catctagcct
    64081 gaaaaatgtc agttttttag atgtttatcg tgatgatgtt cagcgcttaa ctgttctaaa
    64141 aagaatgata gaatttgtta acgattaccc caataatttg aaaggtcttt acttgtatgg
    64201 agactttggt gtgggtaaaa gtttcatggt ggctgcccta gctcatgatt tatcagaaaa
    64261 acgtggtgta tcatccactc tcctccacta tcctagcttt gtcattgatg tcaaaaatgc
    64321 tatcagtgat ggcaatgtta agaccttggt ggatgagatt aagctgtctg aggtcctgat
    64381 tttagatgat attggcgccg agcaatcaac cgtttgggtg cgtgacgaaa tcctgcaggt
    64441 cattctccaa tatcggatgc aggaaaattt accgaccttt ttcacatcca acttcaactt
    64501 tgaagatttg gagaagcatt ttgcgaaagt gaaacatgga aatgacgaaa cctgggaagc
    64561 cagacgggtc atggaacgca tccgttattt ggctgaggag actcgtttag aaggagtaaa
    64621 ccgtcgatga cagaaaccat taaattgatg aaggctcata cttcagtgcg caggtttaaa
    64681 gagcaagaaa ttccccaagt agacttaaat gagattttga cagcagccca gatggcatca
    64741 tcttggaaga atttccaatc ctactctgtg attgtggtac gaagtcaaga gaagaaagat
    64801 gccttgtatg aattggtacc tcaagaagcc attcgccagt ctgctgtttt ccttctcttt
    64861 gtcggagatt tgaaccgagc agaaaaggga gcccgacttc ataccgacac cttccaaccc
    64921 caaggtgtgg aaggtctctt gattagttcg gtcgatgcag ctcttgctgg acaaaacgcc
    64981 ttgttggcag ctgaaagctt gggctatggt ggtgtgatta tcggtttggt tcgatacaag
    65041 tctgaagaag tggcagagct ctttaaccta cctgactaca cctattctgt ctttgggatg
    65101 gcactgggtg tgccaaatca acatcatgat atgaaaccaa gactgccact agagaatgtt
    65161 gtctttgagg aagaatacca agaacagtca actgaggcaa tccaagctta tgaccgtgtt
    65221 caggctgact atgctggggc gcgtgcgacc acaagctgga gtcagcgcct agcagaacag
    65281 tttggtcaag ctgaaccaag ctcaactaga aaaaatcttg aacagaagaa attattgtag
    65341 aaagtgagaa attatggccc taccaactat tgccattgta ggacgtccca atgttgggaa
    65401 atcaacccta tttaatcgga tcgctggtga gcgaatctcc attgtagaag atgtcgaagg
    65461 agtgacacgt gaccgtattt atgcaacggg tgagtggctc aatcgttctt ttagcatgat
    65521 tgatacagga ggaattgatg atgtcgatgc tcctttcatg gaacaaatca agcaccaggc
    65581 agaaattgcc atggaagaag cagatgttat cgtttttgtc gtgtctggta aggaaggaat
    65641 tactgatgca gacgaatacg tagctcgtaa gctttataag acccacaaac cagttatcct
    65701 cgcagtcaac aaggtggaca accctgagat gagaaatgat atctatgatt tctatgctct
    65761 cggtttgggt gaaccattgc ctatctcatc tgtccatgga atcggtacag gggatgtgct
    65821 agatgcgatc gtagaaaatc ttccaaatga atatgaggaa gaaaatccag atgtcattaa
    65881 gtttagcttg attggtcgtc ctaacgttgg aaaatcaagc ttgatcaatg ctatcttggg
    65941 agaagaccgt gttattgcta gtcctgttgc tggaacaact cgtgatgcca ttgataccca
    66001 ctttacagat acagatggtc aagagtttac catgattgat acggctggta tgcgtaagtc
    66061 tggtaaggtt tatgaaaata ctgagaaata ctctgttatg cgtgccatgc gtgctattga
    66121 ccgttcagat gtggtcttga tggtcatcaa tgcggaagaa ggcattcgtg agtacgacaa
    66181 gcgtatcgca ggatttgccc atgaagctgg taaagggatg attatcgtgg tcaacaagtg
    66241 ggatacgctt gaaaaagata accacactat gaaaaactgg gaagaagata tccgtgagca
    66301 gttccaatac ctgccttacg caccgattat ctttgtatca gctttaacca agcaacgtct
    66361 ccacaaactt cctgagatga ttaagcaaat cagcgaaagt caaaatacac gtattccatc
    66421 agctgtcttg aacgatgtca tcatggatgc cattgccatc aacccaacac cgacagacaa
    66481 aggaaaacgt ctcaagattt tctatgcgac ccaagtggca accaaaccac caacctttgt
    66541 catctttgtc aatgaagaag aactcatgca cttttcttac ctgcgtttct tggaaaatca
    66601 aatccgcaag gcctttgttt ttgagggaac accgattcat ctcatcgcaa gaaaacgcaa
    66661 ataaaaaagt agaatctgga atgacagttc cggatttttt tgatataata aaataataga
    66721 aaacgctatc aaaagaagga gggtgatgtc ggtgatggaa catttgttta aattcttact
    66781 tttagcaccg tacttttatt ttgataactg gattgagaag gccaacagaa atagtaagtt
    66841 ttttccaatt ttttattatt tttactggtt ttacatcccc ttctattctc tttttagcct
    66901 tgcttggaca gttgtttcag ttctgttttt caataccgtc ttgagaaatg tgacagatat
    66961 caagttatgg ggcatttggt ttctttttat tctgctagct attggtatga attggttaac
    67021 ttattcctgt ttcaaagaaa tgtttcgctt gagacaggaa ctagggaagt ctaagggtgg
    67081 aaggcattga tttatatcgg tttctatttg taggaggtgg cttatggtac ctctaaaatc
    67141 atttattaca cgctattcca aggtttatat tggtaataac atttaataga acgaaactaa
    67201 agaaaacaat ttaaaaaagg aggcttgtga tggaacactt gtttaaaatg ataatcttat
    67261 taccctgttt ttactttttc agctggattg acaaggataa tagagaaagt aaatttttcc
    67321 caatttttta ctatttttac tggatttaca tcaccctcta tgctcttttt agccttgctt
    67381 ggacagtttt ttcagttctg tttttcaata tcgtcttgag aaatgtggca gacatcaagt
    67441 tatggggtat ttggctatta ttactactta tcgcttttgc tagtgactgg ttagactata
    67501 tctgtttcaa aaaaatgctt gacttgagac gggaactagg gaagtctaaa ggcggaaggc
    67561 attgatttat actcttcgaa aatctcttca aaccacgtca acgtcgcctt ggattatata
    67621 tgtaactgac ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacttgcgg
    67681 ctagtttcct agtttgctct ttgattttca ttgagtatta tattactttc tatttgtagg
    67741 aggtggctta tgaagattcc tctcttaact ttggcaaggc ataaatttgt ttatgtcttg
    67801 cttactttgc tttttcttgc tttggtttat cgtgatgttt tgatgactta tttctttttt
    67861 gatattcatg cgcccgatct agctaaattc gatggacaag caattaaaaa tgacttatta
    67921 aaatcagcat tagattttcg tattctccag ttcaatctag gtttttatca atcatttatt
    67981 attccaatca tcattgtttt gctaggtttt caatatattg agctgaaaaa taaagtttta
    68041 cgattgagta ttggaagaga agtgagttat caagggttaa aaagaaagtt gactttgcaa
    68101 gttgcaagta tcccttgttt gatatattta gtgactgtgc tgataattgc aattttaact
    68161 catttctttg ggactttttc tcctcttgga tggaattctc tattttctga tgggagtagt
    68221 ttacaaaggc tcctagatgg agagataaca agctatttgt tctttacttg tgtcctacta
    68281 atcggtattt tcatcaatgc agtctatttt ttacaaatag ttgattattt aggaaatgtg
    68341 actcgttcgg caatcaccta tttgatgttt ctttggcttg gttctatgct gctctatagt
    68401 gccttgcctt actatatggt tcctatgacg agtttgatgc aagctagcta tggggatgta
    68461 agtttgatga aactctttac tccttatatc ctttatattg tcccttacat ggtgcttgaa
    68521 aaatatgaag ataatgttta agaattttaa caatattttg ctaaagagaa agattgtttt
    68581 actacttcgt atagttctga tgatgatttt gataaaccat ctattgtcaa cagcggttca
    68641 aaagcaggat gctgttatct ttttcaagag agaattgatt tcaatttttt cctataatga
    68701 ctattctgaa gtgaatttag aaatccccaa actcttgtta aacctttcgc ttttcatggt
    68761 aggatggctc tctgtcattt tacttgaaag tgatttggca gaccattacc atcacttgat
    68821 tcgctatcaa tcaagctcct ttttcgatta tacaaggaaa cgattggttg tcatttctaa
    68881 attttttact caagatttgt ttgtctggtt tcttggttta cttcctctag gaattcattt
    68941 caaaacagtc gcacttttct ttttacttgc tcagttaatg atgttgtact tactactgtc
    69001 ttatctgata gcactgatta gtgcgggcgc tggtttttct ttttttctct attttttggc
    69061 atttgtggga caagaatgga tgatggatca tattgtaaca gtgtatttag tactcttaag
    69121 cttattagtt atgttgattc ttagtcgctt ggaagagaaa tttaagaaag gataaacgat
    69181 gagacttgaa attataaatg gacagaaaat ttatgggaaa agacctattt taaatcagtt
    69241 gaatttggtg tttcaatcag gaaaaattta tggacttaaa ggtaataatg gatctggcaa
    69301 gacggttctt ttaaagatac ttgctggtta tattaagctt gacaaaggaa aagttcttca
    69361 agatggtaaa gtttacgggg taaaaaatca ttatattcag gatgcaggaa ttttaattga
    69421 aaaagtcgag tttttatctc atttatccct gagagaaaat ttggaactgt taaggtattt
    69481 ttcatctaaa gttacggaaa aaagaattgc ctattggatt caatactatg atttacagga
    69541 atttgaagac gttgaatacc gtcatttatc cttgggaaca aagcaaaaaa tggccttgat
    69601 tcaagccttt atttcctctc cttctatact ctttctcgat gaacctatga atgctttgga
    69661 tgagaagagt gtgaggttaa ccaaacaggt cattttatct tacctgaaaa aagaaaatgg
    69721 tctggttatc ctgacgtcgc acatatcgaa agatatttca gacctttgta cagatgtatt
    69781 agctgtcgaa aatggacata tacaatatgt aaaggatata caatcctagg agatggctta
    69841 tggcacatct aaaatcattt attacacgct attccaaggt ttatattggt ttagttctgc
    69901 tgatctggct gactttcttc tttatccctt gggatagagc gattctgggg gtaaggattg
    69961 acatcttcat catacagaaa atcttgctag cttttggaat tctgtccatt ttgatggcct
    70021 tgctgtccaa gaaagtcagt ctctttgttt ttggactgat ttgctgtctt tctctttgga
    70081 ttaacttatt tatcacattt gccattttgc cgatttttgg caattaaagc atcataaaag
    70141 tcggagaggt tagcttgaaa actaacctct ttttcctttt caaaatgggg attcttcctt
    70201 gaaaataatc agtaattgtg ctaaaattaa aggaacattc taaaatattc ggaatttaaa
    70261 gtaaggaaaa acatggctaa tattttaaaa acaattatcg aaaatgataa aggagaaatc
    70321 cgtcgtctgg aaaagatggc tgacaaggtt ttcaaatacg aagaccaaat ggctgctttg
    70381 actgacgacc aactaaaagc aaaaacagtt gaatttaagg aacgttatca aaatggagaa
    70441 tcactggatt cattgcttta cgaagcattt gcggttgtcc gtgaaggtgc caaacgtgtc
    70501 ctaggtctct tcccttataa ggttcaggtc atggggggga ttgttcttca ccatggtgac
    70561 gtgccagaga tgcgtacagg ggaagggaaa accttgactg cgaccatgcc ggtatacctc
    70621 aatgcccttt caggtaaagg ggttcacgta gttacggtta atgaatacct gtcagaacgt
    70681 gacgcgactg agatgggtga attgtactct tggcttggtt tgtcagtagg gattaacttg
    70741 gctaccaaat ctccaatgga gaaaaaagaa gcctatgagt gtgatattac ttactcaact
    70801 aactcagaaa tcggatttga ctaccttcgt gacaatatgg tcgttcgcgc tgaaaacatg
    70861 gtacaacgtc cgcttaacta tgccttggtc gatgaggttg actctatctt gattgacgag
    70921 gctcgtacac ctttgattgt atcaggtgcc aatgcggttg aaaccagtca gttgtatcac
    70981 atggcagacc actatgtaaa atctttgaac aaagatgact acatcatcga tgtgcagtct
    71041 aagactattg gtttgtctga ttcagggatt gacagggctg aaagctactt caaacttgaa
    71101 aacctctatg acatcgaaaa cgtggctttg acccacttta tcgataacgc ccttcgtgcc
    71161 aactacatca tgcttctcga tattgactat gtggtgagcg aagagcaaga aatcttgatt
    71221 gtcgaccaat ttacaggtcg taccatggaa ggtcgtcgtt attctgatgg attgcaccaa
    71281 gctattgaag ccaaagaagg tgtgccaatc caggatgaaa ccaagacatc tgcctcaatc
    71341 acgtaccaaa accttttccg tatgtacaag aaattgtctg gtatgacggg tacaggtaag
    71401 actgaggaag aagaattccg tgaaatctac aacattcgtg ttattccaat cccaacaaac
    71461 cgtcctgttc aacgtattga ccactcagac cttctttatg caagtataga atctaagttt
    71521 aaagcggttg tcgaagacgt taaggctcgt taccaaaagg gtcaacctgt cttggttggt
    71581 acagtagcgg ttgaaactag tgactacatt tctaagaaat tggttgcagc tggtgttcct
    71641 cacgaagtct tgaatgccaa aaaccactat agagaagccc aaatcatcat gaatgctggt
    71701 caacgtggtg ccgttaccat cgcaaccaac atggcgggtc gtggtaccga catcaagctt
    71761 ggtgaaggtg ttcgtgaact tggaggactt tgtgttattg gtacagaacg tcatgaaagt
    71821 cgtcgtatcg ataaccagct tcgtggacgt tcaggtcgtc aaggagatcc aggtgagtca
    71881 caattctacc tatctcttga agatgatttg atgaaacgtt ttggttctga acgcttgaag
    71941 ggaatctttg aacgcttgaa catgtctgaa gaggcgattg agtctcgcat gttgacgcgt
    72001 caggttgaag cagctcagaa acgtgtcgaa ggaaataact acgatacccg taaacaagtc
    72061 cttcaatacg atgatgtcat gcgtgaacaa cgtgagatta tctatgctca acgttacgat
    72121 gtcatcactg cagatcgtga cttggcacct gaaattcagt ctatgatcaa acgcacgatt
    72181 gaacgtgtcg ttgatggtca tgcgcgtgcc aaacaagatg aaaaactaga ggcaattttg
    72241 aactttgcta agtacaactt gcttcctgaa gattctatta cgatggaaga cttgtcaggc
    72301 ttgtctgata aggccatcaa ggaagagctt ttccaacgtg ccttgaaggt ttacgatagt
    72361 caggtttcaa aactacgcga tgaagaagca gttaaagaat tccaaaaagt tttgattcta
    72421 cgagtggtgg ataacaagtg gacagatcat atcgatgccc ttgatcaatt gcgtaacgcg
    72481 gttggacttc gtggctatgc tcagaacaac cctgttgttg agtatcaggc agaaggtttc
    72541 cgtatgttta atgatatgat tggttcgatt gagtttgatg tgacacgctt gatgatgaaa
    72601 gcacaaattc atgaacaaga aagaccacag gcagaacgtc atatcagtac aacagcgact
    72661 cgcaatatcg ctgctcacca agcaagtatg ccagaagatt tggatttgag ccagattgga
    72721 cgcaatgaac tttgcccatg tggttctggt aagaaattta aaaactgtca cggtaaaaga
    72781 caataaaatg agatagttta gaggcggata tcttgtgaaa agtaaatttt tactgggtat
    72841 ccgtttgctt tataaggaga tgagttatgg tatttacagc aaaaagctct aaaataaata
    72901 tagaagaagt tcgtgccttg tcaaaattag aaggtcaggc tttggagagg aaatcacagc
    72961 gagatcaaga gctagaagcc attatacgtg gagaagacca gcgaattctc ttggtaatcg
    73021 ggccatgctc atctgacaac gaagaagctg tccttgaata cgctaagcgt ttggcagtcc
    73081 tacaagaaga agtggcagat cgtatcttta tggttatgcg tgtttatact gccaaacccc
    73141 gtaccaacgg agatggctat aagggcttga ttcaccagcc taacgcgaca gaagcgccta
    73201 gtcttatcaa tggaatcaaa gccgttcgcc atcttcacta tcgtgtcatc acagaaacag
    73261 ggatgacaac tgctgatgaa atgctttatc ctgaaaacct tccgcttgta gatgatttga
    73321 tttcttacat ggcagttggt gcccgttcag ttgaagacca gcaacaccgc tttgtggcaa
    73381 gtggggcagg attttctact ggttttaaaa atccaacctc tggaaatctc aatgtcatgt
    73441 ttaatgggat ttatgctgct caaaacaaac aaagtttcct tttcttagga aaagaagtag
    73501 aaacaactgg gaacccgctt tcacacgcta ttcttcgtgg tgctcttaat gagtatggaa
    73561 aaaatattcc caactactat tatgacaatt taattgatac cattgcccag tatgagaaaa
    73621 tgggcttgga aaatcctttt atcatcattg ataccaatca tgacaattct ggtaagcagt
    73681 atattgaaca gatccgaatt gtccgccaga ccttgattaa ccgtgcttgg aatgaaaaaa
    73741 ttaagcagtt cgttcgtggt tttatgattg agtcttatct ggaagatggt cgacaaaatg
    73801 agccagaagt atttggtaag tctatcacag acccttgcct gggttgggat aacacagaag
    73861 ctcttgtcag agaaatttac aaaacgttag gagaataaga tggcatttat tgaaaaaggt
    73921 caagaaatcg atatggaagt catcaaggct gaaacccaat tgtctgcgga agccttgaga
    73981 ctcaaggaaa gccgtgacag ggaattggca gatattattt caggggaaga tgaccgtatt
    74041 ctcttggtga ttggtccttg ctcttctgat aatgaagagg cggtcttgga atatgctcgc
    74101 cgtttatccg ccttgcaaaa gaaggtagcg gacaagattt tcatggtcat gcgcgtgtat
    74161 actgctaagc ctcgtaccaa tggagacggc tataaaggat tggttcacca gccagatact
    74221 tctaaggctc caagcctgat taacggcttg caggctgtgc gccagttgca ctaccgcgtg
    74281 attacagaga ctggtttgac aacggcagat gagatgcttt atccgtcaaa tctgatcttg
    74341 gtggatgact tggtcagcta ccatgccgtt ggagctcgtt ctgtggaaga ccaagagcac
    74401 cgctttgtgg cttctgggat tgatgcacca gtagggatga aaaatccaac ctcaggaaat
    74461 ttgggtgtta tgtttaacgc catctatgct gctcaaaaca agcaaacctt cctttatcat
    74521 gggcaggaag ttgagacatc aggtaatcct ttggcccatg ttatcctccg tggagcagtc
    74581 aacgagtatg gcaattatat gccgaattac tactatgaaa acctactcca agccattgaa
    74641 cgctatgaaa ccatggaact tgaaaatcct tttatcctca ttgacaccaa ccatgataac
    74701 tcaggcaagc aatatatgga gcagattcga attgttcgcc agaccttgca gaatcgtgat
    74761 tggaatgaga aaattaaaaa gacggttcga ggatttatga ttgaatctta cctagcagat
    74821 ggtcgtcaaa accaaccaga ggtctttggt tgctctatta ctgacccttg cctaggttgg
    74881 gaaaatacag aggccttggt agaagagatt tatgttacct tgacaaaata agtgaaaagg
    74941 atggagttgg ggaatctcaa ctccttttga tgagaatgat agttggacac ggaattgaca
    75001 tcgaagaatt ggcttcgata gaaagcgcag ttacacgaca tgaaggattt gctaagcgtg
    75061 tactgaccgc tcaggaaatg gagcgcttca ccagtctcaa aggacgcagg caaatagaat
    75121 atttagctgg tcgctggtcg gctaaggagg ccttttccaa ggctatggga acgggcatta
    75181 gcaagctcgg ttttcaggat ttggaagtct tgaacaatga acgtggggcg ccttatttta
    75241 gtcaggcacc attttcagga aagatttggc tgtctatcag ccacaccgat cagtttgtga
    75301 cagccagtgt cattttggag gaaaatcatg aaagctagtc cacatagacc aaccaaggct
    75361 ctgattcatc tgggagctat tcgacaaaat attcagcaaa tgggggctca tatccctcaa
    75421 ggaacgctca agttggctgt ggtcaaggcc aatgcttatg gtcatggagc tgttgccgtt
    75481 gccaaggcaa ttcaagatga tgttgatggc ttttgcgttt ccaatatcga tgaagccatt
    75541 gaactcagac aagctggact cagcaagcca atcctcattt taggagtttc tgaaatcgaa
    75601 gctgttgctc tagctaaaga atatgacttc accttgacag tggctggact ggagtggatt
    75661 caagcactct tagataagga agtggaccta actggattga cagtccacct caagattgat
    75721 tcagggatgg gacggattgg ttttagagag gccagtgagg ttgagcaggc tcaagatttg
    75781 ctacaacaac acggtgttcg tgttgaagga atctttaccc actttgctac tgctgatgag
    75841 gaatcagatg actattttaa tgcccagtta gaacggttta aaactatttt agctagtatg
    75901 aaggaagttc cagagctggt tcatgctagc aattctgcaa cgactctttg gcatgtagag
    75961 actattttca atgcggttcg tatgggagat gccatgtatg gcctcaatcc aagtggagcg
    76021 gtcttggatt tgccttatga tttgataccg gccttgacct tggagtctgc tctggttcat
    76081 gtcaagacag ttccagctgg agcttgcatg ggctatggag caacttatca agcggatagc
    76141 gagcaagtca tcgcgaccgt gccaatcggg tatgcagatg gatggacaag agacatgcaa
    76201 aatttctctg tcttggtaga tggccaagct tgcccaattg tcggcagggt ttcgatggac
    76261 caaatcacta ttcgattgcc taagctttat ccgctaggaa ccaaggtaac cttgattggc
    76321 tccaatgggg ataaggaaat cactgcaact caggtagcga cctaccgcgt aaccattaac
    76381 tatgaggtgg tttgcctcct cagcgaccgt attccgagag aatattatta gaaaagaaag
    76441 gagtggagca tgaatctaca tcaacccttg catgtcttgc ctggtgtggg accaaagtca
    76501 gcagaaaaat acgccaaact aggaattgaa aacttgcaag atctcttgct ctactttcct
    76561 ttccgttatg aagacttcaa aaccaagcag gtgctggagc tggaagacgg tgagaaggca
    76621 gttctttctg gtcaggtagt gactcctgct agtgtccagt attatggttt caagcgcaat
    76681 cgcctgcgtt ttagtctcaa gcagggagag gtcgtttttg cggtgaattt ctttaaccag
    76741 ccctatctgg ctgataaaat agagttggga gcaacccttg ctgtctttgg aaaatgggac
    76801 cgcgctaagg ctagtctgac tgggatgaag gttctggctc aggtagaaga tgacctccag
    76861 cctgtctatc gtctggctca gggaatcagt caggccagtc tggtcaaggt catcaagacg
    76921 gcttttgatc agggactgga cctcttgata gaagaaaatc tgccccagtc tttactagac
    76981 aaatacaaac tcatgtcccg ttgtcaggca gtccgagcta tgcattttcc aaaggatttg
    77041 gcagaataca agcaggctct tcgccgtatc aagtttgagg aactctttta tttccaaatg
    77101 cagctgcaga cgctcaagtc tgaaaataga gttcagggaa gtggtctggt tctggattgg
    77161 tctcaggaaa aagtgacagc agttaaagca agtcttcctt ttgccctgac ccaagctcag
    77221 gaaaagagtt tgcaggaaat tttaactgat atgaagtccg accaccacat gaatcgtctc
    77281 ctacaaggag atgtggggag tggaaaaacg gtagtcgctg gcttggccat gtttgcggca
    77341 gtgacagcag gttatcaggc tgccctaatg gtaccaacag aaatcctcgc agagcaacac
    77401 tttgagagtt tacagaacct ttttcccaat ttgaaactgg ctctcttgac aggttccttg
    77461 aaagctgcag aaaagagaga agtcttggag accattgcca agggtgaggc tgatttgatt
    77521 ataggaactc acgctctgat acaagatggg gtggagtatg ctcgtcttgg tttgattatt
    77581 atcgatgagc agcaccgttt tggtgtaggg caaaggcgta ttttacggga aaaaggtgac
    77641 aatccagatg tcctcatgat gacggcgact cccattccac ggacgcttgc catcacagcc
    77701 tttggagata tggatgtttc cattatcgac cagatgccag caggtcggaa gcctattgtg
    77761 acgcgctgga tcaaacatga gcaactacct caggtcttga cttggttaga gggggaaatt
    77821 caaaaaggtt cccaagccta tgtcatctct cctttgattg aagaatcaga agctctagat
    77881 ttgaaaaatg ccattgcctt atcagaggag ttgacgactc attttgcagg caaggcagag
    77941 gtggctcttc tacatggtag gatgaagagt gacgaaaaag accagatcat gcaggatttc
    78001 aaggagagaa agacggatat tctggtttcg acgacggtta ttgaggttgg ggtcaacgtt
    78061 cccaatgcga ctgtcatgat tatcatggat gccgatcgct tcggtctcag tcaacttcac
    78121 cagcttagag gtcgtgtcgg tcggggggac aagcagtcct acgctgttct cgttgccaat
    78181 cccaagacgg attctgggaa agaccgcatg cgcatcatga cagaaacgac caatggattt
    78241 gtccttgcgg aggaagattt gaaaatgcgt ggttctggtg agatttttgg aaccagacag
    78301 tcaggacttc cagagttcca agtggctgat attatcgaag attttccgat tttagaagaa
    78361 gcaagaaagg ttgctagcta cattagttct atagaagctt ggcaagaaga tccagagtgg
    78421 cgcatgattg cccttcatct ggaaaagaaa gaacatctgg attaagcttt ctctaaggaa
    78481 aacttaagct agtttttagg tttggctctt atactaaagt catcaaaaag aaacgaggac
    78541 tctcatatga cagtaacgat taaagtaaat taccaaacca ctttccaaaa gaaggaagca
    78601 aaaaactagt ataaacagaa gagagagcga aatgctcttt ttcgtttcta aaactacttt
    78661 cagcccatca tcctaaaagt aaagaatcta aattcacttt ctatttatcc ttctttcttg
    78721 cattgattac atagatatgc tacagttgtg gtaacgatta caaaataaaa ggagcatgct
    78781 atgaaaaatc cagctttgct agaagaaatt aagacctata gaggaaggga tgaggttccg
    78841 gaagactttg atgctttctg ggatggggaa gtgaaaaatg tttccacacc tccatcctac
    78901 cacttggagg aaagagattt ccacattcct caagtcaagt gctatgagtt aacatttgaa
    78961 ggaagcaagg aaggaaaggt ctatgcacgc attgttcttc caaagagtga ggagaaggtt
    79021 ccactaatct tccattttca tggttatatg ggacgtggct gggactgggc cgacatgctg
    79081 ggcttcaccg tagctggtta tggtgttgtt tccatggatg tgcggggcca gtcaggttac
    79141 tcacaagacg gcttgcgttc tcctttagga aataccgtga aggggcatat tatccgtggt
    79201 gctatggaag gtcgggacca cctcttttat aaggatgttt atctggatat ttaccagttg
    79261 gtcgaaattg ttgctagtct gtctcaggtt gatgagaagc gtctttctag ctatggtgcc
    79321 tcacaaggag gggctctagc tctagttgca gcagcgctca atcctcgaat tcagaaaaca
    79381 gttgccattt atcccttctt gtcagacttc agacgggtga ttgagattgg taatactagc
    79441 gaggcttacg acgaactttt ccgttatttc aagtttcacg accccttcca tgaaacagag
    79501 gaggaaatca tggcgaccct tgcctatatc gatgtcaaaa atcttgccca tcgtatccaa
    79561 ggtgaggtta agatgattac gggcttggac gacgatgttt gctatcccat tacccagttt
    79621 gcgatttata atcgtctgac ctgcgataaa acctatcgta tcatgcctga gtatgctcac
    79681 gaagccatga atgtatttgt caatgaccaa gtctacaact ggctctgtgg aagtgagatt
    79741 ccttttaaat atctaaaata aggagtcgac tctaagcaca aaatcttaaa aattacaaac
    79801 acgcatagta tcaggggatt aaaaaaactt gatactatgc gttttatcat ggaaatatag
    79861 taaaatgaaa caagaatagg acaa
//
LOCUS       DAVLZG010000003        56616 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLZG010000003 DAVLZG010000000
VERSION     DAVLZG010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.003"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            104..619
                     /locus_tag="VYO72_000210"
                     /pseudo
     CDS             104..619
                     /locus_tag="VYO72_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(849..1829)
                     /gene="dusB"
                     /locus_tag="VYO72_000211"
     CDS             complement(849..1829)
                     /gene="dusB"
                     /locus_tag="VYO72_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1706657.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1816..2688)
                     /gene="hslO"
                     /locus_tag="VYO72_000212"
     CDS             complement(1816..2688)
                     /gene="hslO"
                     /locus_tag="VYO72_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1706658.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2853..4280
                     /locus_tag="VYO72_000213"
     CDS             2853..4280
                     /locus_tag="VYO72_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1706659.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            4439..5947
                     /gene="glpK"
                     /locus_tag="VYO72_000214"
     CDS             4439..5947
                     /gene="glpK"
                     /locus_tag="VYO72_000214"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1706660.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5989..7815
                     /gene="glpO"
                     /locus_tag="VYO72_000215"
     CDS             5989..7815
                     /gene="glpO"
                     /locus_tag="VYO72_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1706661.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7885..8589
                     /locus_tag="VYO72_000216"
     CDS             7885..8589
                     /locus_tag="VYO72_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1706662.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPISNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8820..8951
                     /locus_tag="VYO72_000217"
     CDS             8820..8951
                     /locus_tag="VYO72_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1706663.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            8972..10522
                     /gene="dltA"
                     /locus_tag="VYO72_000218"
     CDS             8972..10522
                     /gene="dltA"
                     /locus_tag="VYO72_000218"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1706664.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     ITDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            10519..11763
                     /gene="dltB"
                     /locus_tag="VYO72_000219"
     CDS             10519..11763
                     /gene="dltB"
                     /locus_tag="VYO72_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1706665.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            11777..12016
                     /gene="dltC"
                     /locus_tag="VYO72_000220"
     CDS             11777..12016
                     /gene="dltC"
                     /locus_tag="VYO72_000220"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1706666.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            12009..13277
                     /gene="dltD"
                     /locus_tag="VYO72_000221"
     CDS             12009..13277
                     /gene="dltD"
                     /locus_tag="VYO72_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1706667.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            13432..13872
                     /gene="adcR"
                     /locus_tag="VYO72_000222"
     CDS             13432..13872
                     /gene="adcR"
                     /locus_tag="VYO72_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1706668.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            13872..14576
                     /locus_tag="VYO72_000223"
     CDS             13872..14576
                     /locus_tag="VYO72_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1706669.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            14569..15375
                     /locus_tag="VYO72_000224"
     CDS             14569..15375
                     /locus_tag="VYO72_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1706670.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            15385..16890
                     /gene="adcA"
                     /locus_tag="VYO72_000225"
     CDS             15385..16890
                     /gene="adcA"
                     /locus_tag="VYO72_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1706671.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(18018..18791)
                     /locus_tag="VYO72_000226"
     CDS             complement(18018..18791)
                     /locus_tag="VYO72_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1706672.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            18967..20370
                     /locus_tag="VYO72_000227"
     CDS             18967..20370
                     /locus_tag="VYO72_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1706673.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            20485..21123
                     /locus_tag="VYO72_000228"
     CDS             20485..21123
                     /locus_tag="VYO72_000228"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1706674.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            21135..21575
                     /locus_tag="VYO72_000229"
     CDS             21135..21575
                     /locus_tag="VYO72_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1706675.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            21568..21999
                     /locus_tag="VYO72_000230"
     CDS             21568..21999
                     /locus_tag="VYO72_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1706676.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            21990..22460
                     /locus_tag="VYO72_000231"
     CDS             21990..22460
                     /locus_tag="VYO72_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1706677.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            22485..23258
                     /locus_tag="VYO72_000232"
     CDS             22485..23258
                     /locus_tag="VYO72_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1706678.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            23255..24055
                     /locus_tag="VYO72_000233"
     CDS             23255..24055
                     /locus_tag="VYO72_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1706679.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            24114..26408
                     /locus_tag="VYO72_000234"
     CDS             24114..26408
                     /locus_tag="VYO72_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1706680.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            26418..29534
                     /locus_tag="VYO72_000235"
     CDS             26418..29534
                     /locus_tag="VYO72_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1706681.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            29617..31383
                     /locus_tag="VYO72_000236"
     CDS             29617..31383
                     /locus_tag="VYO72_000236"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1706682.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            31529..32680
                     /locus_tag="VYO72_000237"
     CDS             31529..32680
                     /locus_tag="VYO72_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1706683.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            32825..33709
                     /locus_tag="VYO72_000238"
     CDS             32825..33709
                     /locus_tag="VYO72_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1706684.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(33746..33949)
                     /locus_tag="VYO72_000239"
     CDS             complement(33746..33949)
                     /locus_tag="VYO72_000239"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706685.1"
                     /translation="MKIKEQTRKLATGCSKHCFEVVDKTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVADRTDEVSNIYTARRR"
     gene            34153..34404
                     /locus_tag="VYO72_000240"
     CDS             34153..34404
                     /locus_tag="VYO72_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1706686.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            34392..34682
                     /locus_tag="VYO72_000241"
     CDS             34392..34682
                     /locus_tag="VYO72_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706687.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(35086..36417)
                     /locus_tag="VYO72_000242"
     CDS             complement(35086..36417)
                     /locus_tag="VYO72_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1706688.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLTDKE
                     ELVELLTRCAQNYQLRYEEFDYLASLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(36439..37950)
                     /locus_tag="VYO72_000243"
     CDS             complement(36439..37950)
                     /locus_tag="VYO72_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1706689.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(38159..39106)
                     /gene="arcC"
                     /locus_tag="VYO72_000244"
     CDS             complement(38159..39106)
                     /gene="arcC"
                     /locus_tag="VYO72_000244"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1706690.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(39271..40287)
                     /gene="argF"
                     /locus_tag="VYO72_000245"
     CDS             complement(39271..40287)
                     /gene="argF"
                     /locus_tag="VYO72_000245"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1706691.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(40345..41574)
                     /gene="arcA"
                     /locus_tag="VYO72_000246"
     CDS             complement(40345..41574)
                     /gene="arcA"
                     /locus_tag="VYO72_000246"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1706692.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            42330..44009
                     /locus_tag="VYO72_000247"
     CDS             42330..44009
                     /locus_tag="VYO72_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1706693.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(44049..46133)
                     /locus_tag="VYO72_000248"
     CDS             complement(44049..46133)
                     /locus_tag="VYO72_000248"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1706694.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            46304..47584
                     /locus_tag="VYO72_000249"
     CDS             46304..47584
                     /locus_tag="VYO72_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1706695.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            47675..50320
                     /locus_tag="VYO72_000250"
     CDS             47675..50320
                     /locus_tag="VYO72_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1706696.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKVLHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            50404..51273
                     /locus_tag="VYO72_000251"
     CDS             50404..51273
                     /locus_tag="VYO72_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1706697.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            51267..53147
                     /locus_tag="VYO72_000252"
     CDS             51267..53147
                     /locus_tag="VYO72_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1706698.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVTIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            53501..53863
                     /locus_tag="VYO72_000253"
     CDS             53501..53863
                     /locus_tag="VYO72_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706699.1"
                     /translation="MPKTKTLAKLADVILWSFDFANDHAHAFFMDNVEWSHADSYFFS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(53915..54304)
                     /locus_tag="VYO72_000254"
     CDS             complement(53915..54304)
                     /locus_tag="VYO72_000254"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1706700.1"
                     /translation="MKAQAIVTSQGRIVSLDITVNYCHDMKLFKMSCRNIGQAGKILA
                     DSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKACNHALSKERSKVENIFAKVKTFKIIS
                     TTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(54330..54536)
                     /locus_tag="VYO72_000255"
     CDS             complement(54330..54536)
                     /locus_tag="VYO72_000255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1706701.1"
                     /translation="MREYRTYEEIAADFGIHESNFIRRSQWVEVTLVQSGFTVSRTPL
                     SSEDTVMIDATEVKINRPKKTISE"
     gene            complement(54719..54895)
                     /locus_tag="VYO72_000256"
                     /pseudo
     CDS             complement(54719..54895)
                     /locus_tag="VYO72_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            55230..>56616
                     /gene="pcpA"
                     /locus_tag="VYO72_000257"
     CDS             55230..>56616
                     /gene="pcpA"
                     /locus_tag="VYO72_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1706702.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT        17082 a        10396 c        12438 g        16700 t
ORIGIN      
        1 agaggtacca aaggttccag atacaccaaa ggctccggac acaccgcagg ttccagaagc
       61 accaaaggct ccagacacac cgcaaattcc ggaagcacca gctccagaaa ctccggctcc
      121 agctccagaa gctccaaaaa caggctggaa acaagaaaac ggtatgtggt acttctacaa
      181 tactgatggt tcaatggcaa caggctggct agaatacaat ggctcatggt actatctcaa
      241 cgctaatggt gctatggcaa caggttggct agaatacaat ggttcatggt actacctcaa
      301 tactaatggt gctatggaga caggttggct agaatacaat ggttcatggt actacctcaa
      361 tactaatggt gctatggaga caggttggct agaatacaat ggttcatggt actacctaaa
      421 tgctaacggt tcgatggcaa caggttggct gaaagatgga gatacatggt actatcttga
      481 agcatcaggg gctatgaaag aaagccaatg gttcaaagta tcagacaaat ggtactatgt
      541 caatggctca ggtgcccttg cagtcaacac aactgtaggt ggctatagag tcaatgccaa
      601 tggtaaatgg gtaaactaaa cctaatgtaa ctcgttaatg ctggcttcct gtaagaactc
      661 tttaaagtat tccctacaaa taccatatcc tttcagtaga tactataccc ttgtaggaag
      721 tttagattaa aaaataactc tgtaatctct agccggattt atggcgctag agactacgga
      781 gtttttttga tgaggaaaga atggcggcac tcaagagact ctttaagaga gttacgggtt
      841 ttaaactatt aagccttctc caattgcaag agagcttcaa tctctgccag ggtgctagct
      901 tgtgaaatgg ctccacggag tttggcagcg ccagatgttc cacggagata gtgaggagcg
      961 aggccgcgga attcacgaac ggcgacgttt tctcctttga ggttaatcaa tcgtttcaag
     1021 tgttcgtagg cgatcttcat cttgtcttca aaggtcaaat caggtaggat ttctcctgtt
     1081 tcaaagtaat ggttgatttg gttgaagagg taaggatttc ccatggcagc tcggccaatc
     1141 atgactgcgt cagcaccaac ttcttcgatg cgttgcttgg cttcttggac agtacggata
     1201 tcaccgttgg cgatgaatgg aatcttggtt agagcttggg caaccttgta aagggtctca
     1261 aggtctgcgt ggccagtata catttgttca cgggtacggc catgcatggc gagggcagaa
     1321 acacctgcag cttcagcagc gagggcattt tctactgcca gagatgggtc cgcccatccg
     1381 gtacgcattt tgacagtaag ggggatatca aggacagact gaaccttgtt gatgatagag
     1441 tagatcttgt caggatcctt gagccacata gctccagctt cgttcttcac gattttgttg
     1501 acagggcagc ccatgttgat atcgacgata tcggtcttgg tgttttcttg gatgaattct
     1561 gctgcgcgtg ctaggctgtc ttcatcgcta ccaaaaagtt ggatagagac agggttttcg
     1621 ccctcatcga tatgaagcat gtgcagggtt ttttcgttgt tgtattggat tcctttgtca
     1681 gagaccattt ccattacaac gagtccagct ccgagctctt ttgcgatggt acgaaaggct
     1741 gagttggtca cgccagccat aggcgctaaa acggtacgat tgggaatctc aacattgcca
     1801 atcataaaag gtgtattaag atttgtcacg aatgagttcc tccaggtcct tttcatcaaa
     1861 gttgtaagta gtttggcaga attgacaagt gatttctgcc ccgtggtctt cttctttcat
     1921 ttcctgtaag tctgagcttg gaaggctggc aagagcgttc ataaagcgtt catggctaca
     1981 gtcacattgg aaacggattt cttcttcaga aagacgcttg taggcttcgt ccccgtagat
     2041 agccttgagg agggcttcga tatggtcgtc gctttcgaga agagtagaga tagctggcat
     2101 ttcttggatg cgtttttcaa agcgagcaat ctcttctttc ttggctcctg gcaagacttg
     2161 aactaggaaa ccacctgcaa ccttgacctt gtcttcctcg tccaaaagga cattgaggcc
     2221 gaccgctgaa ggcgtttgtt ggctttcagt aaggtaaaag gcaaggtctt caccgatttc
     2281 tccggagatg aggggagtta tagagttgta aggatttcca gtaccgtagt ctgtgataac
     2341 gaggaattga ccatttccaa caaaaggtcc gactaggact tcaccagtcg cagtcttttt
     2401 gatgtcaaca ccaggatttt gaacgtagcc tttgacgttc cccttggtat cagcgacggt
     2461 gataatagca cctagagagc tagatcccaa caccttaact gtaagtttgg tatttccttt
     2521 ttcattggct gcgagaatct ggctagcgat aagagttcga ccaagcgcta cagttgagct
     2581 agcttgggtt tggtgttttt cttgagcagt gcggacggtt tccgtgctgt caaggacaaa
     2641 agcacgaaag gctccgcttt ctgatatagt tttaataatt ttattcatag ctactatttt
     2701 agcataaaaa tgcccagagg gggagccgtg tgtttactga ttttcaggat aatggaccag
     2761 gaaatcagca tgaaaataaa aagagaaaca gattatttca gcatttgtaa gatttatgct
     2821 atgcttaagg tagaaaatga aaggggtaac aaatgtattt aggagatttg atggagaaag
     2881 ctgagtgtgg tcaattttca atcctttcct ttctattaca agagtctcag acgaccgtca
     2941 aggctgtaat ggaagaaaca ggattttcaa aagcaaccct aaccaaatat gtcaccctgc
     3001 tcaatgacaa ggctttggat agtggcttag agctgactat tcactcagaa aatgaaaatt
     3061 tgcgtctgtc tatcggtgca gctaccaagg ggagagatat tcggagctta tttttggaga
     3121 gtgctgttaa ataccagatt ttggtttatc ttctctacca ccaacagttt ttagcccatc
     3181 agctggctca agaattggtg attagcgagg ctacgcttgg tcgtcacttg gctggtttaa
     3241 atcagattct gtcagaattt gatttatcca tccaaaatgg acgttggcga ggtccagagc
     3301 atcagattcg ctatttctat ttctgtcttt tccgaaaggt ctggtcgagt caggaatggg
     3361 aaggtcacat gcagaaacca gagagaaaac aggagattgc caatttagag gaaatctgcg
     3421 gtgcaagttt gtctgtgggg cagaaattgg acttggttct ctgggctcac atcagtcaac
     3481 aacgtcttcg ggtcaatgct tgtcagtttc aagtcataga agagaaaatg cgagggtatt
     3541 ttgacaatat cttttatctt cgtttgctga gaaaggttcc gtcctttttt gctgggcaac
     3601 atattccact aggagttgag gatggtgaga tgatgatatt cttctctttt ctcctatctc
     3661 atcgcattct tcctcttcat actatggagt atattcttgg ttttggaggg cagttggcag
     3721 atttactgac gcaattgatt caagaaatga agaaggagga actattgggg gattatacag
     3781 aggaccatgt cacctatgaa ctcagtcagc tttgtgctca agtctatctc tataagggct
     3841 atattttaca ggatcgctac aagtaccagt tagagaatcg tcatccatat ttactgatgg
     3901 aacatgattt taaagagaca gcagaggaga tttttcatgc tctacctact tttcaacagg
     3961 ggacagattt agataagaag attctctggg aatggctcca gttaatcgaa tatatggctg
     4021 aaaacggtgg ccagcatatg cggattggtc tggatttgac atctggtttt cttgtctttt
     4081 caaggatggc agccattttg aaacggtatt tggaatacaa tcgttttatt accattgaag
     4141 cttatgaccc tagtcggcat tatgatttgc tggttaccaa taacccgatt cataagaagg
     4201 aacagacacc agtctattat ttaaaaaatg acttggatat ggaggatttg gtagcgattc
     4261 gccagttatt attcacttaa aaggcttggt taatccaggt cttttttgtg aaattcacac
     4321 aatctcctca cattttttta aaaattaaaa aaagttgata aacaagaaag cgctttattt
     4381 tgtatactag taagtgtaaa gaggaaacac ctcaagatct ttatcaggag gacagtacat
     4441 gtcacaagaa aaatacatca tggccattga ccagggaact acaagttctc gtgccatcat
     4501 tttcaacaaa aaaggggaaa aggttagctc gagtcaaaaa gagtttaccc agattttccc
     4561 tcaggcaggt tgggttgagc acaatgccaa tgaaatttgg aactctgttc agtcagttat
     4621 tgcgggtgct ttcatcgaaa gtggtgtcaa gccaaatcaa atcgaggcaa tcgggattac
     4681 caaccaacgt gaaacaacgg ttgtctggga taagaaaaca ggacttccta tctacaatgc
     4741 tatcgtttgg cagtcacgcc agacagcacc tttggctgag caactaaaaa gccaaggtta
     4801 tgtggaaaaa ttccatgaaa agactggttt gattattgat gcttacttct ctgctaccaa
     4861 ggttcgttgg attttggatc atgtagaagg tgctcaagag cgagcagaaa aaggggaatt
     4921 gctctttggt actatcgata cttggttggt ttggaaattg actgacggtg cggctcacgt
     4981 gactgactac tcaaatgcag ctcgtaccat gctttataac attaaagaac tcaaatggga
     5041 tgatgagatt ttggaaatcc ttaacattcc gaaggctata cttccagaag ttcgttctaa
     5101 ctccgaaatc tacggcaaga cagctccatt ccatttctac ggtggagagg tgccaatctc
     5161 aggtatggct ggggaccaac aagcagccct ctttggacag ttggcttttg agccaggtat
     5221 ggttaagaat acttatggaa caggctcttt catcatcatg aatactgggg aagagatgca
     5281 gttgtctgaa aacaacctct tgacaaccat tggttacgga atcaacggta aggtttatta
     5341 tgccttggaa ggttctatct tcatcgcagg aagtgctatt cagtggcttc gtgacggtct
     5401 tcgcatggtt gaaaattcac cagaatctga aaaatacgct cgtgattctc acaacaacga
     5461 tgaagtttat gtcgttccag cctttacagg tctaggcgct ccatactgga accaaaatgc
     5521 tcgtggttcc gtctttggtt tgactcgtgg aacaagcaaa gaagacttta tcaaggcgac
     5581 tttgcaatct attgcttatc aagtgcgtga tatcatcgac accatgcaag tggatactca
     5641 gaccgccatt caagtactga aggtggatgg tggtgcagcc atgaacaact tcctcatgca
     5701 gttccaggcg gatattttag gcattgacat tgcacgtgct aaaaacctgg aaacaacagc
     5761 tctaggagcg gccttcctag caggtttgtc agtagggtac tggaaagact tggacgagtt
     5821 gaaactcttg aacgagacag gagaactctt tgagccatct atgaacgaat ctcgcaagga
     5881 acaactctac aagggctgga agaaggctgt gaaagcaact caagtctttg cggaagtaga
     5941 cgactaatac tggcagaata aagcgattta tttagaaagt gtgtaaatat ggaattttca
     6001 aagaaaacac gtgaattgtc aattaaaaaa atgcaggaac gtaccctgga cctcttgatt
     6061 atcggtggag gaatcacagg agctggtgta gccttgcagg cggcagctag cggtcttgag
     6121 actggtttga ttgaaatgca agactttgca gaaggaacat ctagtcgttc aacaaaattg
     6181 gttcacggag gacttcgtta cctcaaacaa tttgacgtag aagtggtctc agatacggtt
     6241 tctgaacgtg cagtggttca acaaatcgct ccacacattc caaaatcaga tccaatgctc
     6301 ttaccagttt acgatgaaga tggagcaacc tttagcctct tccgtcttaa agtagccatg
     6361 gacttgtacg accttttagc aggtgtgagc aacacgtcag ctgcgaacaa ggttttgagc
     6421 aaggatcaag tcttggaacg ccagccaaac ttgaagaagg aaggcttggt aggaggtgga
     6481 gtgtatcttg acttccgtaa caacgatgcg cgtctcgtga ttgaaaacat caaacgtgcc
     6541 aaccaagacg gtgccctcat tgccaaccac gtgaaggcag aaggcttcct ctttgacgaa
     6601 agtggcaaga ttacaggtgt tgtagctcgt gatctcttga cagaccaagt atttgaaatc
     6661 aaggcccgtc tggttattaa tacaacaggt ccttggagtg ataaagtacg taatttgtct
     6721 aataagggaa cgcaattctc acaaatgcgc ccaactaagg gagttcactt ggtagtggat
     6781 tcaagcaaaa tcaaggtttc acagccagtt tacttcgaca caggtttggg tgacggtcgt
     6841 atggtctttg ttctcccacg tgaaaacaag acttactttg gtacaactga tacagactac
     6901 acaggtgatt tggagcatcc aaaagtaact caagaagatg tagattatct acttggcatt
     6961 gtcaacaacc gctttccaga atccaacatc accattgatg atatcgaaag cagctgggca
     7021 ggtcttcgtc cattgattgc agggaacagt gcctctgact ataatggtgg aaataacggt
     7081 accatcagtg atgaaagctt tgacaacttg attgcgactg ttgaatctta tctctccaaa
     7141 gaaaaaacac gtgaagatgt tgagtctgct gtcagcaagc ttgaaagtag cacatctgag
     7201 aaatatttgg atccatctgc agtttctcgt gggtctagct tggaccgtga tgacaatggt
     7261 cttttgactc ttgctggcgg taaaatcaca gactaccgta agatggctga aggagctatg
     7321 gagcgcgtgg ttgacatcct caaagcagaa tttgaccgta gctttaaatt gatcaattct
     7381 aaaacttacc ctgtttcagg tggagaattg aacccagcaa atgtggattc agaaatcgaa
     7441 gcctttgcgc aacttggagt atcacgtggt ttggatagca aggaagctca ctatctggca
     7501 aatctttacg gttcaaatgc accgaaagtc tttgcacttg ctcacagctt ggaacaagcg
     7561 ccaggactca gcttggcaga tactttgtcc cttcactatg caatgcgcaa cgagttggct
     7621 cttagcccag ttgacttcct tcttcgtcgt accaaccata tgctctttat gcgtgatagc
     7681 ttggatagca tcgttgagcc agttttggat gaaatgggac gattctatga ctggacagaa
     7741 gaagaaaaag caacttaccg tgctgatgtc gaagcagctc tcgctaacaa cgatttagca
     7801 gaattaaaaa attaagaaaa aataaaagag gtggagggca gcattccttg tcgctcgtcc
     7861 cttcttttta atggagacag aaagatgatg aatgaattat ttggagaatt tctagggact
     7921 ttaatcctga ttcttctagg aaatggtgtt gttgcaggtg tggttcttcc taaaaccaag
     7981 agcaatagct caggttggat tgtgattact atgggttggg ggattgcagt tgcggttgca
     8041 gtatttgtat ctggcaagct cagtccagct catttaaatc cagctgtgac aattggtgta
     8101 gctttaaaag gtgacttgcc ttgggcttcc gttttgcctt atatcttagc ccagttcgca
     8161 ggggctatgc tgggtcagat tttggtttgg ttgcaattca aacctcacta tgaggcagaa
     8221 gaaaatgcag gcaatatcct ggcaaccttc agtactggac cagccatcaa ggatactgta
     8281 tcaaacttga ttagcgaaat ccttggaacc tttgttttgg tgttgacaat ctttgctttg
     8341 ggtctttacg attttcaggc aggtatcgga acctttgcag tgggtacctt gattgtcggt
     8401 atcggtctat cgctaggtgg gacaacaggt tatgccttga atcctgcgcg tgaccttgga
     8461 cctcgtatca tgcacagtat ccttccaatt tcaaacaagg gagacggaga ctggtcttat
     8521 gcttggattc ctgttgtggg acctgttatc ggtgcagcct tggccgtgct tgtattctca
     8581 cttttttagt ttagaaaata actattattg ctagagcttg agatgaaaat ctcaggcttt
     8641 tttcttttga aatagatata gaaaaaccgc ataatcctta aaataagctg aaatctattg
     8701 gaaacatacg gtaaacaatt gaaaagatac tatataaagt ggtacaatgg tagaaaaata
     8761 agctagtaag aatcactctt attttagcga aaaattacag aaatgaatgg tttttcttga
     8821 tgaaacagag aaaagaattg tacctctttc ttggtcggac agccttgtat tttcttatct
     8881 ttctagggct gctttacttc tttagctatc ttggtcaggg tcaaggaagc tttatctata
     8941 atgaatttta acttgaagga gaatccctat tgtgtcaaat aaaccaatag cagatatgat
     9001 tgaaaccatt gagcattttg ctcagacaca gcctagctat cctgtctata atgttttggg
     9061 gcaggaacac acttatggcg atttaaagtc tgattcggat agtttggctg cagtcattga
     9121 ccaactaggc ttgcctgaga agtctcctgt ggttgttttt ggtggccaag aatatgaaat
     9181 gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc tacattccaa ttgatagcca
     9241 ttcggccttg gagcgagttt cagctatttt agaagtagca gagccaagct tgattattgc
     9301 catttcagcc tttcccttgg agcaggtttc tacaccaatg ataaatctag ctcaggttca
     9361 agaagccttt gcccaaggga acaactatga aatcacgcat ccagtcaagg gagatgataa
     9421 ttactacatt atctttactt ctggtacgac tggtaagcct aagggagtgc agatttcaca
     9481 tgataatctc ctcagcttta caaactggat gattacggat aaggaatttg cgacaccgag
     9541 tcgtccgcaa atgctggcac agccacctta ttcttttgac ttgtctgtca tgtattgggc
     9601 accgaccttg gcacttggtg gtacgctttt cactcttcct tcagtcatca ctcaggactt
     9661 taagcaactc tttgcggcta tcttttcatt gccaatcgct atctggacat caacaccatc
     9721 ctttgcagat atggccatgt tgtctgaata cttcaacagt gaaaaaatgc ctggaatcac
     9781 gcatttctac tttgatggtg aagaattgac ggtcaaaaca gctcaaaaac tgcgcgagcg
     9841 tttcccaaat gcccgtatca tcaatgctta cggcccaaca gaagcgacag tagctctgtc
     9901 agcagttgcc gtgacagacg agatgttagc gactctcaaa cgcctaccaa tcggctatac
     9961 caaggctgat tctccaacct ttatcattga cgaggaagga aataaactgc caaatggcga
    10021 acagggagaa atcattgttt ctgggccagc tgtttcaaaa ggttatatga acaatcctga
    10081 aaaaacagca gaagccttct ttgagtttga aggtctgcca gcctatcaca caggcgatgt
    10141 gggaaccata acagatgagg gcttgcttct ctacggcgga cgcatggact tccagattaa
    10201 gttcaacggt taccgcattg agttagaaga tgtctctcaa aacctcaaca agtctcgctt
    10261 tatcgaatct gctgtcgcag taccgcgcta taacaaggac cacaaggtac aaaatctatt
    10321 ggcttatgtc atcttaaaag acagtgttcg tgagcagttt gagcgagata tcgatattac
    10381 caaggccatc aaggaagacc tgacagacat catgatgtcc tacatgatgc catctaaatt
    10441 cctttaccga gacagtttgc cactgactcc aaatggaaag attgacatca aaggattgat
    10501 taacgaggtg aataagagat gatggagttt tttcaacagc ttcctcattt agagccatat
    10561 ggcaatcctc agtattttgt ttatgtgatt gctgcaacct tgcccatctt tataggcctc
    10621 tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa gtctcttctt tattgtcacc
    10681 atgttggtgg gtggaaagac caatcaacta gctgccttgg gtatttacct ttgctgggaa
    10741 atattgctcc tgcttttcta caagcattat cgaaaaagca aggatggcaa gtgggtcttc
    10801 tacttagtta gttttctgtc cctacttccg attatctttg tcaaggtgca accagctatc
    10861 aatggaacgc agtctttgct tgggttcttg ggaatttctt acctgacctt tcgttcggtt
    10921 gggattatca tcgagctgag agatggagtg attaaggatt ttaccctctg ggaattcctc
    10981 cgtttccttc tcttcatgcc aactttctcg agtggtccaa tcgatcgctt taagcgattt
    11041 aatgaaaatt atcaggctat tcctgagcga gatgagttga tggatatgct ggatgaatct
    11101 gtccgctata tcatgtgggg ctttttgtat aagtttatcc tagctcatgt tttaggagag
    11161 accttactac ctcctctgaa gaatttagcc ttgcagtcag gtggcttctt taatctctat
    11221 gccttggcag ttatgtatac ttttggtctg gagctcttct ttgactttgc aggttattct
    11281 atgtttgctt tggccatctc aaacttgatg ggaatccgta gccctatcaa ctttaacaag
    11341 ccctttttat caagggattt aaaggagttt tggaatcgct ggcatatgag tctgtccttc
    11401 tggttccgtg actttgtctt tatgcgaatg gtgatggtgt taaccagaaa gaaagtcttt
    11461 aaaaatcgta atgtaacctc aagcatggcc tacattgtaa atatgctgat tatgggattt
    11521 tggcatggtg tgacctggta ctatatcgcc tatggactct ttcatggact aggcttggtc
    11581 atcaatgatg cctgggttcg caagaaaaaa acgctcaata aggaacggaa aaaagcaggg
    11641 aaggctgccc tacctgagaa tcgctggatt cagttgcttg gcatggttgt cactttccat
    11701 gttgtcatgt tgtcattctt aatcttttct ggattcttga ataatctatg gtttaaaaaa
    11761 taaaaggaaa taaaatatgg atatcaaatc agaagttatt gaaattattg atgagttgtt
    11821 tatggaagat gtttctgaca tgatggatga agatcttttt gatgcaggtg tcttggatag
    11881 tatgggaacg gttgagttga ttgtggagat tgagaaccgt tttgacattc gtgtccctgt
    11941 aacagagttt ggtcgtgacg actggaatac agctaataaa atcatagctg gtattgtgga
    12001 gctacaaaat gcttaaacgc ttatggatga tcttcggacc ggtcttgatc gctggtttgt
    12061 tggtttttct gctcattttc ttttatccta ctgagatgca tcataatcta ggagctgaaa
    12121 agcgttcagc agtggctact actatcgata gttttaagga gcgaagtcaa aaagtcagag
    12181 cactatctga tccaaatgtg cgttttgttc ccttctttgg ctctagtgaa tggcttcgtt
    12241 ttgacggtgc tcatcctgcg gtattagctg agaaatacaa tcgttcctac cgtccttatc
    12301 ttttaggaca ggggggagct gcatcgctta accaatattt tggaatgcaa cagatgttac
    12361 cacagctgga gaataaacaa gttgtgtatg ttatctcacc tcagtggttc agtaaaaatg
    12421 gctatgatcc agcagccttc cagcagtatt ttaatggaga ccagttgact agttttctga
    12481 aacatcaatc tggggatcag gctagtcaat atgcagcgac tcgcttactg caacagttcc
    12541 caaacgtagc tatgaaggac ctggttcaga agttggcaag taaaggagaa ttgtcgacag
    12601 cagacaatga aatgattgaa ttattggctc gttttaatga acgccaagcc tccttttttg
    12661 gtcagttttc ggttagaggc tatgttaact acgataagca tgtagctaag tatttaaaaa
    12721 tcttgccaga ccagttttct tatcaagcaa tagaagatgt tgtcaaagca gatgctgaaa
    12781 aaaatacttc caataatgag atgggaatgg aaaattattt ctataatgag cagatcaaga
    12841 aggatttgaa gaaattaaag gattctcaga aaagctttac ctatctcaag tcgccagagt
    12901 ataatgactt gcagttggtt ttaacacagt tttctaaatc taaggtaaac ccgattttta
    12961 tcattccacc tgttaataaa aaatggatgg actatgctgg tctacgagag gatatgtacc
    13021 aacaaacggt gcagaagatt cgctaccagt tagaaagtca aggttttacc aatatagcag
    13081 atttttctaa ggacggtggg gagcctttct ttatgaagga caccattcac cttggttggt
    13141 tgggttggtt ggcttttgac aaggcagttg atcctttcct atccaatccc acaccagctc
    13201 cgacttacca tctgaatgag cgctttttca gcaaagattg ggcgacttat gatggagatg
    13261 tcaaagaatt tcaatagata atataatata gaagagttca agaatgaaac tagttttcac
    13321 gttttttctt gactcttttt ttgcttgtga tataattaac tggtaaacaa aatgtcaaag
    13381 aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa aggagtcaga tatgagacag
    13441 ctagcaaagg atatcaatgc ttttttgaat gaggtgattt tgcaggcgga aaatcagcat
    13501 gaaatcctaa taggtcattg cactagcgag gtggccctga ccaatactca ggagcatatc
    13561 cttatgctct tgtcagagga atctttaaca aattcagaat tggcccgtcg tctcaatgtc
    13621 agtcaggcgg cagttaccaa ggccattaag tctttggtca aggaagggat gttggaaaca
    13681 tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt tgactgactt ggctcgtcca
    13741 atcgctgagg agcaccacca tcaccatgag catacacttt taacctatga acaagtggcg
    13801 actcagttta ctccaaatga acaaaaagtg attcagcggt ttttgactgc tttagtagga
    13861 gaaatcaaat aatgagatat attacggtag aggatttgtc cttctattat gataaggagc
    13921 ctgttcttga acatatcaat tatagtgttg atagtgggga atttgttacc ttgactgggg
    13981 aaaatggagc ggctaagacg acgctcatca aggccagtct tggaattctg caaccacgca
    14041 ttggaaaggt ggctatttca aagacaaata cgcaaggtaa gaaattgaga atagcctatc
    14101 ttcctcaaca aattgccagt tttaatgctg gttttccaag tacggtctat gaatttgtca
    14161 agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt gaatgctcat gatgaggagc
    14221 atatcaaggc cagtctggac tcagttggca tgtgggaaca tcgagacaaa cgcttggggt
    14281 ctctatctgg gggacaaaag cagcgagcgg taattgcgcg tatgtttgct tctgaccctg
    14341 atgtgtttat cctagacgag ccgacaacgg ggatggatgc aggaagtaaa aatgaatttt
    14401 acgaactcat gcaccacagc gcccatcatc atggcaaggc tgttttgatg attacccatg
    14461 accctgaaga agttaaggat tatgcggatc gcaatattca tctagtccgt aaccaagact
    14521 cgccatggcg ttgtttcaac gttcatgaga atggccagga ggtgagccat gcttagttta
    14581 ttatcttacg actttataca acgcgccttt ttggcggtta ttgctatgag tcttttctca
    14641 ccggtattgg gaaccttcct catcttgcgt cgtcagagtt tgatgagtga tacccttagc
    14701 cacgtctcac tttcaggtgt agcctttggt ctggttttgg ggatttctcc aactgtttct
    14761 actattgcca ttgtcttgat tgcggcggtc tttctggagt atctccgtac ggtttacaag
    14821 agctttatgg aaatcgggac agctatcctc atgtcaacag gtctggctgt ttctctgatt
    14881 gtcatgagca agggtaaaag ctcgagttca atgagtttgg accaatatct ctttggttcg
    14941 atcgtgacta tcagtgaaga acaggtcatt tccctctttg tcattgcggc ggttgttttg
    15001 attttgacct ttctctttct tcgtcctatg tatatcttaa cttttgatga agatacggcc
    15061 tttgtggatg gcttgccagt tcgtaccatg tccattcttt ttaacatggt gacaggggtg
    15121 gctattgccc ttatgattcc tgcagcagga gctcttctgg tatcgaccat tatggtcttg
    15181 ccagctagta ttgccctgcg tctggggaaa aactttaaat cggttatgct gcttgccagt
    15241 gcgattggct ttttgggaat ggtagcagga ctttacattt cctactatgc agaaacacct
    15301 gcaagtgcaa gtattaccat tatttttgta actgtcttta tactaatcag tttagtaaga
    15361 cgttttatca aataggagac gaacgtgaaa aaaattagct tattactagc cagtctatgt
    15421 gccttgtttt tagtggcttg ttccaatcaa aaacaggcag atggtaaact caatatcgtg
    15481 acaacctttt accctgtcta tgaatttacc aagcaagtcg caggagatac ggctaatgta
    15541 gaactcctaa tcggtgctgg gacagaacct catgaatacg aaccatctgc caaggcagtt
    15601 accaaaatcc aagatgcaga taccttcgtt tatgaaaatg aaaacatgga aacatgggta
    15661 cctaaattgc tagatacctt ggataagaaa aaagtgaaaa ccatcaaggc gacaggcgat
    15721 atgttgctct tgccaggtgg cgaggaagaa gagggggacc atgaccatgg agaagaaggt
    15781 catcaccatg agtttgaccc ccatgtttgg ttatcaccag ttcgtgccat taaactagta
    15841 gagcacatcc gcgacagctt gtcagcagat tatcctgata aaaaagagac ctttgagaag
    15901 aatgcagctg cctatatcga aaaattgcaa gccttggata aggcttacgt agaaggcttg
    15961 tctcaagcaa aacaaaagag ctttgtgact caacacgcag cctttaacta tcttgccttg
    16021 gactatggac tcaaacaagt cgcaatctca ggactttctc cagatgcaga gccatcagct
    16081 gctcgcttgg cagaattgac agagtatgtc aagaaaaata aaatcgccta tatctatttt
    16141 gaagaaaatg cctcacaagc ccttgctaac acactttcaa aagaagcagg tgtcaaaact
    16201 gatgtcctca atcctttaga aagtctgaca gaagaggaca ccaaggctgg agaaaattac
    16261 atctctatca tggagaaaaa cctcaaggct ttgaaacaaa caacagacca agaaggccca
    16321 gcaatcgagc ctgaaaaggc agaggatacc aagacagtcc aaaatggtta cttcgaggat
    16381 gcagctgtca aggaccgcac cttgagtgac tatgcaggta actggcaatc agtttatcct
    16441 ttccttgaag acggcacgtt tgaccaagtc tttgactaca aggctaagtt gactggtaag
    16501 atgacccagg ctgagtacaa ggcttactat acaaaaggct atcagacaga tgtgactaag
    16561 attaacatta ctgataatac tatggaattt gttcaaggtg gacaaagcaa gaaatacact
    16621 tacaagtatg tcggtaagaa aattttgact tacaagaaag gcaatcgtgg cgtgcgtttc
    16681 ctctttgaag ccacagatgc tgacgctgga caattcaagt atgttcagtt tagtgaccac
    16741 aatatcgccc cagttaaggc agaacatttc catatcttct ttggaggcac aagccaagaa
    16801 gccctctttg aagaaatgga caactggcca acctactacc cagataacct atctggccaa
    16861 gaaatcgccc aagaaatgtt ggcgcattga tgagaaatcg actagttcat aagagctagt
    16921 cggttttttg atactagatg gctaacttca ttatagacct ttcagaacta agggaacctg
    16981 aaaaaataaa taaaactctt gaaatattag gacttatatg ctagaatgta gttagtgtat
    17041 aaggttcatt agaacaccaa agcccctaac tagtgccata gttaagggct tttttgacgt
    17101 atcttagtga tttaacgggt gtttataggc tagtcagtcg gtctacttct taccatctag
    17161 ccatttgcag acgaaataca agataattcc agctataaca tctgctataa tagtaagagc
    17221 aagctctggt ataaggctca ttagtttcac ctcctctcac gaacccatag gaacgtaatc
    17281 ggtaaccgat gacaaaaata gtataccaca ctaaatttag atcatcaacc tcacttaatg
    17341 cttgaactat tgtagattat atgctaaaat gtagttaatt gataaggttc attagaacac
    17401 caaagcccct aactatggcc gtagttaagg gcttttttga cgtatcttag agatttaacg
    17461 ggtgtttata ggctagtcat tcggtctact ccttactatc tagccatctg cagatgaaat
    17521 acaagataat tccagctata acatccgcta taatagtaag agcgagctct atgataaggc
    17581 tcattagttt cacctcctct cacgaaccca taggaacgta atcggtaacc gatgacaaaa
    17641 atagtatacc acaatacatt tagatcatca aggtcactta attcttgaaa tatagggtct
    17701 aggcgacaaa gtctttaaaa tcagaaaaac gcataatatc aggtgtgcaa aaacttgata
    17761 ctatgcgttt tattgtggga atatttgccc catttctctt gaaattgagt ttttgtccag
    17821 cctctgtttt tagggttgct aagaaaataa tgtcatgtgg tgaatatttg taaatcagtc
    17881 agcagacaga acgagtattc ttcgaaaatc tcttcacatc atgtcagctt cgtcttgccg
    17941 tgtccatggg ggacttgact tcatcagttt tcaaatctgt actttgagca agctgagact
    18001 agcttcctat ttgattttca ttgaatatca gaaacccatt ctccatcaaa taattcgact
    18061 gcgtctaata atttttgatc tggcacggtg tcagaaataa aggttgtgta tttggatagg
    18121 ggattaattt taaaaaatcc agtcttgtaa aatttagagc tatcaatcag taagatggtt
    18181 tcatgggctt tgtcaataat attctttttt gaaatagctt ggctgagaga agcttcataa
    18241 acatattggt catcaatacc tcttgctgaa caaaatgcta aatcgatatt aaaatgatct
    18301 aataaagaat tttccttatc gtaattgacc acggaacagg attgatgttt gacctcgcca
    18361 gatgtgataa agattttgga gctatcttta acagtttcag atagggtttg tgcagtatgt
    18421 aaaccatttg taaaaataat caaattatca agttcagaaa gatagggaca aagttcgtag
    18481 acagtcgtac tggaatccag ataaacacac atacctgacc gaataaagtc tttagcgaga
    18541 ctagcgatta gtcttttttg cctagtactt tctccttccc gtatttgatg agaaagttca
    18601 attgtgttca tagaggacag ggtcacgtat ccgtgctttc ttttgataag accttgattt
    18661 tctaagaaaa ttaaatcacg acgtaaggta cttgtgctgg agaaagtgat ttctgccagc
    18721 tcttttacgg caattctttt tttcttttta ataatttcaa tcaattcaag tacacgttca
    18781 tcttttatca taagctcctc ctaatttatc atttcaacta tattatagca caaattggag
    18841 gaatttgaat tatttttatg aatattgggt taacatttga acattatcca agtaagcgtt
    18901 cacatattga aaaaataaaa tgtggggatt ataataaact taatcaagga cgaagagaga
    18961 agaaaaatgg aagcggtttt agcaatagat ttaggtgcga cttctggaag agcaatcgtt
    19021 ggttaccttt ctgaaaataa actagtaatg gaagaaataa atcgcttttc taatctacct
    19081 attagagtaa aagggcattt atcttgggat attgactttc tactagctaa aattcttgaa
    19141 agtatccgct tggctaatac tagttacaag attttatcta tcggtattga cacatgggga
    19201 gttgattttg gactgattga taatgaaggt aagctgttat cacaacctgt tcattatcgt
    19261 gatgaaagaa caaagggagt gttaaaggaa atatctgaaa tgactgaatt agaaaaactg
    19321 tattcagaga caggaaatca gattatggag ataaatacct tgtttcaact ctttaaggca
    19381 cgtcaagaat ctcctgactc tttctataag accaataaga ttcttttaat gccagatttg
    19441 tttaattatc tcttgacagg taagtttgct acagaaaaaa gcattgcttc aacaactcaa
    19501 ttatttgatc ctaggagtca aaattggaat cagaatatct taaaactatt tgaattggat
    19561 tcatctttac ttcctgaaat tgtttcagag ggaaatgttc ttggaaggat aaaaaaggag
    19621 tatggtttag gcgatattcc tgttgtgaat gtttgtagtc atgatacagc aagtgcgatt
    19681 gtctcagtac ctaagacaga aggtagttta tttatttcat caggtacttg gtctttggtt
    19741 ggagtggaac ttacttcacc gattcttact accgaatcct tcagttatgg atttacaaat
    19801 gaagtcggta aagatggagt gattacattt ctgaagaatt gtacagggtt gtggatcata
    19861 gaggaactaa gacgttcatt tgaacgaaga gggaaagcct attcttttga tgatattagg
    19921 acaatggtgg agaaagaaaa agaaaatctt cctctgattg atactgaatc aactgaattt
    19981 gcaacagaat ctgatatgca caagactttg acagaatatc tagcttatca tcatgaaact
    20041 agagagtgga cagatggaca actatttaag attgtttatg aaagcctagc tgaaacgtat
    20101 aggaaagcga tagagttact agaagaacta actcataagg tttataagag gatatatgtg
    20161 attggaggag gtgctagagc cagttacttt aaccaaatga ttgctgatag aactggtaaa
    20221 gaggttctta caggttcgac tgagggtaca gctgtgggga atattgttgt gcagctcata
    20281 gctatgggac aattaaaagg gatggaagaa gctcaccatg ttattgagga gtttctacaa
    20341 ttagagagtt attactccca aaagaattaa aaagattgag agtttgtaaa tttgcctccc
    20401 tcccccttct taagttttgt acaagaaggg gggataattg gtgaattgaa aaatatttag
    20461 tgttttgata tgaggaggac aagaatgtca gatgtaaaac aagaattaat taagtatggc
    20521 aagaagctag tagaaacaga tttgacgaaa ggaacaggtg ggaatctcag tgttttcgat
    20581 cgtgaaaaac aattgatggc aattaccccg tcgggtattg atttctttga aatcaaagaa
    20641 tccgatattg tagtgatgga tattaatgga aatgttgtag agggagaacg cttgccatct
    20701 agcgaatggt atatgcattt gattcaatat caaactcgtg atgatatcga tgcaattatc
    20761 catgctcata caacttatgc aacagtatta gcttgtctca gagaaccact tccggctagt
    20821 cattatatga ttgcagtggc agggaaagat gttcgggtag ctgagtatgc aacatatggt
    20881 acgaaagaat tggctgtgaa tgcagctaaa gcaatggaag gtcgtagagc agttttacta
    20941 gcgaatcatg gaattttagc aggtgcacaa aatttattga atgcatttaa tattgttgaa
    21001 gaagttgaat attgtgcaaa aatttattgt ttagctaaga attttggaga gccagtagtt
    21061 cttcctgatg aggagatgga tttaatggca gaaaaattta aaacatacgg tcagagaaaa
    21121 tagggaggat attaatgtta aaacatatac cgaaaaatat ttctccagat ttattgaaga
    21181 ctttaatgga aatgggacat ggagatgaaa tagtattagc tgacgcgaat tatccttctg
    21241 cctcatgtgc aaataagcta attcgttgtg atggcgtaaa tattccagaa ttattagatt
    21301 ccattctgta tttaatgcca ttagatagtt acgtcgatag ttcaattcag tttatgaacg
    21361 ttgtttcggg tgatgatatt cctaagatat ggggtaccta tagacagatg attgaaggtc
    21421 atggtacaga tcttaaaacg attacttatc ttagaagaga agacttttat gaacgtagta
    21481 agaaagctta tgctattgtt gctacaggag aaacttcact ttatgctaat attatcctta
    21541 agaaaggagt agttgttgaa agagaaaatg tttaatagag gaattttagt tgccagtcat
    21601 ggtaattttg ctagcggagc tctcatgacc gcagaaatgt ttgttggtga gacaacaaat
    21661 gatagagtta ggacattagg tttgatgcct ggagagaata ttgtagagtt tgaacattat
    21721 tttaaaaatc aagtggatga actgttagac tcaaatcaag aggttatcgt tttgactgac
    21781 ttgattggag gaagtcctaa taatgtggct ttgtcacggt ttttaaattt ggattcagtt
    21841 gatattgtaa cagggtttaa tatccctctc ctagtggaat taatatcaag ttatgattca
    21901 aaaatcaatt tagaagaaat tgttcaaaat gctcaaaata gtttgtttaa tgttaaacaa
    21961 caacttaacg tagaggagga agaggattta tgtctataga gtttgttcgt attgatgacc
    22021 gtctggtaca tggtcaagtt gtcactacgt ggctaaaaaa gtatgatatt gagcaagtta
    22081 tcattgttaa tgatcgcatc tcagaagata aaacacgaca atctatttta aagatttctg
    22141 caccggtagg tttaaaaatt gttttcttta gtgtaaaacg gtttgtggaa gttttaaact
    22201 ctgtgccaat aaaaaagaga acaatgctga tatatacaaa tccaaaagat gtgtatgatt
    22261 ctattgaagg aaatttaaaa ttggagtacc tcaatgtagg acagatgagt aaaacggagg
    22321 aaaatgaaaa ggtaacggga ggtgtagctc taggtgaaga agacaaatat tattttaaga
    22381 aaatagttga taagggaacg agagttgaaa ttcaaatggt tcctaatgat aaagttacaa
    22441 tgttggaaaa atttttataa aaataattta aggaggtaca gtatatgcta ttcacacaag
    22501 cattactggt gacattagtt gggattattg ccactattga ctataatgga ccgttattta
    22561 tgattcaccg tccgttagtt acaagtgcaa tggttggctt agtcttagga gatttcaccc
    22621 aaggtgttct tattggttca gctcttgaat taacttggct cggtgtaaca ggtattggag
    22681 gttacactcc accagatact atttcaggtg cgattattgg tactgcattt ggtattttat
    22741 ctggtcaagg agaaactgct ggtatcgcta tagcagttcc aattgcagtt gctacccaac
    22801 agttggatgt tcttgcaaaa actttagatg tttattttgt gaaaaaagct gataatgatg
    22861 ctaaaaacgg agattattca aagatcggtt tttatcatta ttcaagtttg gttttaatca
    22921 cgttatttaa aattgtacca attttcctag ctattatgct tggaggggaa tatgtggcag
    22981 acttgtttgc taaggttcca ccaatcgtta tgcagggact taactctgca ggtgctttac
    23041 taccttcaat tggttttggt atgcttttaa atatgatgct caagaaaaat atgtgggtat
    23101 tcttgttgat tggattcatt tgttctgtgt atggaggaat gtcaaccatt gggatctcac
    23161 tagttggtat tgcggtagca tacttctacg atatgattgg aagtaaacca caagaaacaa
    23221 cttcaagtag tgatgttgag gaggatcttg atctatgatg aataataaag taactaaagt
    23281 tgaacttaaa aaagttttca aacgaagttt tatgtatggt tcttcatgga actatgagag
    23341 aatgcagaac ctaggttttc tatatacaat tcttccagta ttgaaaaaac tatacccaga
    23401 caaagattca gcttctcctg caatgaaacg tcaccttgag tttttcaata ctcatcaaac
    23461 agcggcacca tttattcttg gagttacttc cgctatggaa gaacaagaag gaaatgaagg
    23521 tgcagcttca attactggta ttaaagttgg cttgatgggg ccactggctg gtctaggaga
    23581 tagtttgttc tggctgacac tagttcctat ctgttttagt attggtgcgt cttattctaa
    23641 agacggcggt gctttaggta tctttatcgc cttaatattg tttaatatta ttaatattcc
    23701 tgttaaatat ttcggtttga aatatgggta tactaagggt tctagtctta tccaagaaaa
    23761 taatacaaaa ggaacattga atcgcgttac gagtatggcg acagcattag ggctagtact
    23821 agtgggtggt ttgattccat caatggttgg tattaatttt ggattagaat ttaagcaggg
    23881 ggaacttgtt atttctgttc aagaaatgat tacaaaatta attccaggat ttatccctat
    23941 ggctttgact ttattaatgt gtaaattaat tagaaaagga aagaatccgg ttgtactaat
    24001 ctttagtgtt atggctattg gagttatcct agttgtttta ggaattttga agtagtagaa
    24061 agtgtggagg tggtatttgg gatatcacct ccattttgga agagaggtaa agagtgaaat
    24121 tatggtataa gaaagctgcc tcaaattgga atgaagcctt gccgattggg aacggtcatt
    24181 taggtggtat gatttatggt tcagctacaa aagaatgtat tcaactaaac gatgagacta
    24241 tttggtatag aggaaagtca gatagaaata atccagactc actattgcat cttaaaaaaa
    24301 ttcgggaata tcttttagat ggagaaattc agaaagccga agaattgata aagttaacaa
    24361 tgtttgctac cccaagagat caaagccact atgaattact tggggaactt tacattgagc
    24421 atatagatat tcagtcttgt gctctttcat tgtatgaaag agagctagat ttagatacag
    24481 ctatttctaa tgttgtgttt gagcctaata gttgtaattt acaaataaaa agagaatatt
    24541 ttacgagttt taataagaat attttatgtt gccgtatagt gtcatcagtt caaaacacat
    24601 taaatttaaa cattaatttg ggtagaaata aacggtttaa tgacgaagta tctaaactgg
    24661 attcaagtac aattttaatg tcggcctctg ctggaggtag aaaaggtgtt cagtttaaag
    24721 tagtatgtca ttctaaggtt acggatggtg aagtaagtgt attgggagag acaatagtta
    24781 ttcggaatgc tacagaggta tttctttatc tcaaatcaat gacggattat tggggaaata
    24841 tagatatttc ttctcttcag ggagaattta gtagtattga ttactttaca gaaaaagatg
    24901 aacatgtaaa aaaatatcag gagcaattta atagagttga ttttaaacta gactatagta
    24961 aagattgtct tagcattcca acgaatctac ttcttgaaaa cactaaaaag tatagtaact
    25021 acttgactaa cttgttattt cattatggaa gatatctgtt aatatcgtct agtcaaccga
    25081 atggtttacc tgccaatctt caaggaatat ggtgtgatga attaaatcca atttggggtt
    25141 ctaaatatac gattaatatt aatactcaaa tgaattattg gatggtaggt ccatgtgatt
    25201 taccagaagt agaatatcca ttatttgata tgctcgaaag aatgagagaa ccgggaagac
    25261 taaccgctaa gaaaatgtat ggagctagag gttttacagc acatcataat acggatggtt
    25321 ttggcgatac ggctccccaa tctcatgcca tgggggctgc aatttgggta ttaactattc
    25381 catggttatg tactcatatt tgggaacact atttatattt ccaagatgag cgtattctta
    25441 cggaacattt tgaaatgata aaagaagcat ttcttttctt tgaagattat ttatttgagg
    25501 tggatggcta cttgatgaca ggtccaagtg tctcaccgga aaataaatat cgcttaaaaa
    25561 atggtattga aggaaatgct tgtctatcat ctacaattga taatcaaatt ctaagatatt
    25621 tttgtgattc atgcattggc attgcaaaac aattaggaga caattcggat tttattagtc
    25681 gtgtgaagga gttaaaaaag aaactaccta aaacaaaaat aggtagtaat gggcaaatcc
    25741 aagaatggtt agaagattat gaagaagtag agcctgggca tagacacatt tcacctctat
    25801 ttgggcttta tccttataat gagattgata ttcataaaac tccggaatta gcagaagcag
    25861 ctaaaatcac tatcaatagg agattatcaa acgctaattt tttatcttca caggagaggg
    25921 agcaagcgat taataattgg ttagtaagtg gtttgcatgc tagtacacaa acaggttgga
    25981 gtgctgcatg gctgattcat ttttttgcga gactatatca aggtgaacct gcttataacc
    26041 agattaatgg tttgttaaat aatgcgactc ttggcaattt atttcttgac catccaccat
    26101 ttcaaattga tggtaattta ggtttggtga gtggaatttg tgaattatta gtacagagcc
    26161 atcataattg gttatcacta attccagctt taccttctgc ttggtcagaa ggagaagtga
    26221 aaggtttcag agtaagagga ggatataagg tatcgtttgc ttggaaaaat ggggatataa
    26281 cattcctaaa attggaagga ggaaacaaag atcaaaaagt aagagtaaga atatatggca
    26341 aaaatactga tgtacaaaat attgaattgg tatttaattc agaaaaaatt attgagttaa
    26401 atttttaggt ataagtcatg aataaagaaa aaataaaaag aaaattaatc acaatattgt
    26461 ttgtatgtat tgggatgtta tgttttggat tgttagcagg agttaaggct gataatcgtg
    26521 ttcaaatgag aacgacgatt aataatgaat cgccattgtt gctttctccg ttgtatggca
    26581 atgataatgg taacggatta tggtggggga acacattgaa gggagcatgg gaagctattc
    26641 ctgaagatgt aaagccatat gcagcgattg aacttcatcc tgcaaaagtc tgtaaaccaa
    26701 caagttgtat tccacgagat acgaaagaat tgagagaatg gtatgtcaag atgttggagg
    26761 aagctcaaag tctaaacatt ccagttttct tggttattat gtcggctgga gagcgtaata
    26821 cagttcctcc agagtggtta gatgaacaat tccaaaagta tagtgtgtta aaaggtgttt
    26881 taaatattga gaattattgg atttacaata accagttagc tccgcatagt gctaaatatt
    26941 tggaagtttg tgccaaatat ggagcgcatt ttatctggca tgatcatgaa aaatggttct
    27001 gggaaactat tatgaatgat ccgacattct ttgaagcgag tcaaaaatat cataaaaatt
    27061 tggtgttggc aactaaaaat acgccaataa gagatgatgc gggtacagat tctatcgtta
    27121 gtggattttg gttgagtggc ttatgtgata actggggctc atcaacagat acatggaaat
    27181 ggtgggaaaa acattataca aacacatttg aaactggaag agctagggat atgagatcct
    27241 atgcatcgga accagaatca atgattgcta tggaaatgat gaatgtatat actgggggag
    27301 gcacagttta taatttcgaa tgtgccgcgt atacatttat gacaaatgat gtaccaactc
    27361 cagcatttac taaaggtatt attcctttct ttagacatgc tatacaaaat ccagctccaa
    27421 gtaaggaaga agttgtaaat agaacaaaag ctgtattttg gaatggagaa ggtaggatta
    27481 gttcattaaa cggattttat caaggacttt attcgaatga tgaaacaatg cctttatata
    27541 ataatgggag atatcatatt cttcctgtaa tacatgagaa aattgataag gaaaagattt
    27601 catctatatt ccctaatgca aaaattttga ctaaaaatag tgaggaattg tctagtaaag
    27661 tcaactattt aaactcgctt tatccaaaac tttatgaagg agatgggtat gctcagcgtg
    27721 taggtaattc ctggtatatt tataatagta atgctaatat caataaaaat cagcaagtaa
    27781 tgttgcctat gtatactaat aatacaaagt cgttatcgtt agatttgacg ccacatactt
    27841 acgctgttgt taaagaaaat ccaaataatt tacatatttt attgaataat tacaggacag
    27901 ataagacagc tatgtgggca ttatcaggaa attttgatgc atcaaaaagt tggaagaaag
    27961 aagaattaga gttagcgaac tggataagca aaaattattc catcaatcct gtagataatg
    28021 actttaggac aacaacactt acattaaaag ggcatactgg tcataaacct cagataaata
    28081 taagtggcga taaaaatcat tatacttata cagaaaattg ggatgagaat acccatgttt
    28141 ataccattac ggttaatcat aatggaatgg tagagatgtc tataaatact gaggggacag
    28201 gtccagtctc tttcccaaca ccagataaat ttaatgatgg taatttgaat atagcatatg
    28261 caaaaccaac aacacaaagt tctgtagatt acaatggaga ccctaataga gctgtggatg
    28321 gtaacagaaa tggtaatttt aactctggtt cggtaacaca cactagggca gataatccct
    28381 cttggtggga agtcgatttg aaaaaaatgg ataaagttgg gcttgttaaa atttataatc
    28441 gcacagatgc tgagactcaa cgtctatcta attttgatgt gattctatat gacaataata
    28501 gaaacgaagt tgctaagaaa catgttaata atttgtcggg tgaatctgtt agtctagatt
    28561 tcaaagaaaa aggagcaagg tatattaaag ttaaattact aacgagtgga gtgcctttga
    28621 gtttagcaga agtagaggtt tttagagaat cagatggtaa gcaatctgaa gaggatatag
    28681 ataaaataac agaagataaa gtagtctcta caaataaggt agctactcaa agttcaacca
    28741 attatgaggg tgtagctgct ttagcagttg atggtaataa agatggagat tacggacatc
    28801 attcggtgac tcatactaag gcagattcta acgcttggtg gcaggtcgat ctgggagaag
    28861 agtttacggt ttctaaagtt gatatttata atagaacaga tgccgaacct cagcgtttat
    28921 ctaattttga tgttattttt ctatcttcat caggagaaga agtttttaga agacattttg
    28981 ataaagtagt tgatggtttg ttatctttaa aagtaccttc tgtaggggct aagctagtca
    29041 aaatagaatt aaaatcagca gctattccgt taagtttagc ggaagttgaa gtctatggtt
    29101 caaagagaac tccgaagaaa ctttctaata ttgcattaac aaaagaaact cgacagagtt
    29161 caacggatta caatggtttt tctcgtctag cagttgatgg aaataaaaac ggagattatg
    29221 gtcatcattc agtgactcat accaaagaag attctccttc atggtgggag atagatttag
    29281 cacaaaccga agaattagaa aagttaatta tttataatag aacagatgct gaaattcaga
    29341 gattatcaaa ttttgatatt attatatatg attcaaatga ttatgaagtt tttacacaac
    29401 atattgacag tttagaaagc aataatctat ccatagactt aaaaggactg aagggaaaaa
    29461 aggttagaat ttctttgaga agcgcaggaa ttcctttaag tttagcagag gtagaggttt
    29521 atacttataa gtaattttaa aaattatcac ccaggctacc gtaaatataa tggagatggt
    29581 agtatgaaag aaacagaaaa ataagaggaa aatagtatga ttcaacatcc acgtattggg
    29641 attcgtccga ctattgatgg tcgtcgtcaa ggtgtacgcg aatcacttga agtgcaaaca
    29701 atgaacatgg ctaaaagtgt ggcagatttg atttcaagca cattgaaata tccagatggg
    29761 gaacctgtgg aatgcgtgat ttctccatct actattggcc gtgtaccaga ggctgcagct
    29821 tcccatgagt tgtttaaaaa atcaaatgtt tgcgcaacaa ttacagttac accatgctgg
    29881 tgttatggta gtgaaactat ggatatgtct ccagatattc ctcatgctat ttggggattt
    29941 aatgggacag aacgcccagg agctgtctat cttgcagctg tactagcttc acatgctcaa
    30001 aaagggattc cagcctttgg gatttatgga agagatgttc aggaagctag tgacacagat
    30061 attccagaag atgtcaaaga aaaactttta cgctatgcgc gtgcagctct tgcaactggc
    30121 ttgatgagag acactgctta cctatcaatg ggtagtgttt cgatggggat tggtggttct
    30181 attgtaaatc cggatttctt ccaagaatac ctaggaatgc gaaatgaatc ggtagatatg
    30241 acggagttca cgcgccgtat ggaccgtagt atttacgacc ctgaagagtt cgaacgtgcg
    30301 ctcaaatggg tgaaagaaaa cgtaaaagaa ggattcgacc ataaccgtga agaccttgtt
    30361 ttaagccgtg aagaaaaaga tagacaatgg gaatttgtta ttaagatgtt catgattgga
    30421 cgtgacttaa tggttggtaa cccaagactt gctgaacttg gttttgagga agaagcagtt
    30481 ggtcaccatg ctttagtagc tggtttccaa ggtcaacgtc agtggacaga ccattttcca
    30541 aatggagatt ttatggaaac tttcctcaat actcagtttg actggaatgg tattcgaaaa
    30601 ccatttgtat ttgcgacaga gaatgattca ctaaatggtg tgtctatgct ctttaattat
    30661 ctattaacaa atactccaca aatctttgct gatgtgcgta cttattggag cccagaggct
    30721 gttaaacgtg taacgggaca tactttagag ggtcgtgctg cagctggctt cttacatcta
    30781 atcaactctg gttcttgtac attggatggt acaggtcaag ctactcgaga tggcaaacct
    30841 gttatgaaac cattctggga gttggaagaa agtgaagtgc aggctatgct tgaaaataca
    30901 gacttcccac cagcaaaccg cgaatacttc cgtggaggag gattctcaac tcgtttcttg
    30961 acgaaggggg atatgccagt aacaatggta cgtctcaatc ttctaaaagg ggttggtcca
    31021 gtgctacaaa ttgcagaagg ttatacactt gaacttcctg aagatgttca ccatacttta
    31081 gataatcgta cagatccagg atggccaact acttggtttg ctccacgttt gacaggaaaa
    31141 ggtgctttca agtctgtcta tgacgtcatg aataattggg gagctaatca cggagccata
    31201 acatatggac acattggagc agacttgatt accttggctt ctatgttgag aattcctgtc
    31261 aatatgcata atgtacctga ggaagatatc tttagaccta aaaattggtc cttatttgga
    31321 acagaagatc tagaatcagc agactattgt gcatgtcagt tgttgggacc actacataaa
    31381 taaaacttgt ttatatagga ggtgaactta cgtccctcct atccttttaa aaagatttgt
    31441 taaacaattc acaaataatt aaaaacgaat acaaaaagta atataatgat gttaaataga
    31501 tagcgcggag gcgcaggagg aaaattatat ggctacattt tatgttccgg cagtcaacct
    31561 tattggaaaa ggtgttgtaa atgaagtggg tccttatatc aaggaacttg gctataaaaa
    31621 ggcacttttg gttacagata agtacatcga aggcagtgat attttaccta agactttaaa
    31681 accactggat acagaaggaa tcgaatatgt catctttagc gatgtagagc caaaccctac
    31741 ttgtaaaaat gtcacagatg gggtagctgc tttgcaagaa catggctgtg actttatcat
    31801 cagtcttggc gggggttctc cacaggatgc agctagttgt atttctatca tggctacaaa
    31861 tggtggaaaa ccacaggatt atgaagggct tcataagtct gctaaaaaag gcttgccagt
    31921 tgtggctatc aatacaacgg caggaacttc tgcagaaatc actattaact atgtgattac
    31981 tgatgaagaa cgcaaggtta agatggtaat ggttgacaag aatagccttg ctcttatctc
    32041 tgttaatgac ccggaactca tgctttccaa acctaaaggc ctgactgctg ctactggtat
    32101 ggatgctctg actcacgctg ttgaagcttt ggtaacacct ggtgcttatg atgtaaccaa
    32161 gaaactgtct attggtgcta ttgagcttat caaggaatat cttcctcgtg ctgtagaaaa
    32221 tggacatgat attgaagcgc gtgaaggtat ggtcaatgcc atcttccttg gtggtatgag
    32281 ctttaataat gctggtcttg gttatgttca ctcaatggct caccaactcg gtgcagtata
    32341 taatttgcca catggcgtgt gctgtgccat gttgctacca gttatagaac gtgaaaatgc
    32401 taaacgtgta ccagaagctt tccgcaatgt tgccaaagcc ttgggacttc atgtagaagg
    32461 taaatcagat caagaatgtg ccgattatgc gattgctgag attgagaagc tttctgagac
    32521 agtaggtatt cctaagaaac tgactgaact tggtattgaa gaaaaagatt tcgactttga
    32581 atacctttct aagaatgcct tgattgatgc ctgcgcacca ggaaatccat ttatgccaac
    32641 cttagaagaa acgattgcct tttataaaga gttattttag caagagattg gacgacaata
    32701 ggacaattca cctctaatta ttgacatttc aggaaaaatc gcagtaaaaa cggcacagcc
    32761 ttctttaaat gtgctataat actagaaaaa tacttgtgga ggttccatta tggcaatatt
    32821 tttcatgatt tttctgattg tttgtgtgct cctattggtg atagtcacac tgagtacagt
    32881 ttatgtggtt cgtcagcagt cggtggcgat tattgaacgc tttgggaaat accaaaaggt
    32941 tgctaatagc ggtattcata ttcgcttgcc ttttgggatt gactcgattg cagcacggat
    33001 tcagttgcgc ttgttgcaaa gtgatattgt ggttgagact aagaccaagg acaatgtgtt
    33061 cgttatgatg aatgtagcga ctcagtaccg tgtcaacgag cagagcgtga cagatgctta
    33121 ctataaactc atacgtccag aatctcagat taaatcttat atcgaagatg ctcttcgctc
    33181 ttctgttcca aaattaacct tggatgaatt gtttgagaaa aaagatgaga ttgcccttga
    33241 ggttcaacac caagtagcag aagaaatgac cacttacggc tacattatcg tgaaaacctt
    33301 gattaccaag gtcgaaccag atgcagaagt taagcaatcc atgaatgaaa tcaatgcggc
    33361 gcaacgtaag cgggtcgcag cacaagaatt ggcggaagct gacaagatta aaattgtcac
    33421 tgcagctgaa gcagaagcag aaaaagaccg ccttcatggt gtggggattg cccaacaacg
    33481 taaggcgatt gtggatggat tggcagagtc tatcaccgaa ctcaaggaag ccaatgttgg
    33541 catgacagaa gaacaaatca tgtctatcct cttgaccaac cagtatttgg ataccttgaa
    33601 tacctttgcc tctaaaggaa atcaaaccat ctttttacca aatactccaa atggtgtgga
    33661 tgatatccga acacaaatct tgtcagccct tcgcgctgag aagaaataat agactaatac
    33721 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttgc cgtatagatg ttactgactt
    33781 cgtcagttct atctgcaacc tcaaaacagt gttttgagct gacttcgtca gttctatcca
    33841 caacctcaaa acagtgtttt gagctgactt cgtcagtctt atctactacc tcaaaacagt
    33901 gttttgagca acctgtggct agtttcctag tttgctcttt gattttcatt gagtacaaag
    33961 agcttggcaa caggctcttt ttgtattgcg tttattaaga aaaacaaaaa acatcgatat
    34021 acatttaact aaaaattatt gtatgttatc tcccttaatt aggaatgata agggaataac
    34081 tagaaagatt tgtgaataca aactatttct gatatacaaa atatacagta ataatgaatg
    34141 atgggagatg ggatgaaaga atttcaattt gagagaaagc agcgtttttc tttgaggcca
    34201 tatgcaatag gagcttgttc ggtcttgcta ggaacgagtt tattttttgc tggtatgggt
    34261 gctcagcctg tacaggatac agaaacgagt tcagcactaa tttcaagtca ttatttggat
    34321 gagcaggatt tatctgaaaa gctgaaatct gagttgcaat ggtttgaatt agaaaacaag
    34381 cttttgaact tatgggagca ttaggttact atgaaggatt tgttccttat gtttcaaatc
    34441 aatacaaaaa ccaagctgaa gaagaaggca aaccgctatc tgataaatat attttcgaaa
    34501 aaatcttagg aaaaacatat gcagccttca aaaaagatca aattaatgag cgtgtcgaga
    34561 aattaggtaa gttaaaacct attacaataa attacaacgg aaaatcagaa gtaattgata
    34621 gtaaagaaaa attacaagag cttatgaata aagccgttaa agacgaagtg gctcaaatat
    34681 agtaaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaaaaat
    34741 gttttagaag tagaggtgta ctattctagt ttcaatatac tataaaatca ggcaatacca
    34801 cggctaaaaa gtttgagttt atcgaaacac cagtgcaaaa actgaaaaaa gcgatttata
    34861 aagctcatct caaagattca gatgacttta gaccagaaac atccacacca aatctttttg
    34921 aaagctgttt gaagctttgt ccttgctttc ttagttcata gatctgaact ttatcttcat
    34981 aactcaattt cataataaaa caccccaaaa gttagattta ttctgtctaa cttttggggt
    35041 gcagttcatt ttgcgggatt ttttttggta gaaacagttg cctgattaag ttgcaagtcg
    35101 atagacggct tcggcataaa tatccatagc acggtacaaa tcttctagaa cggcacattc
    35161 atttgcctga tgttctgtct gcttcgctcc tgggaataag gcgccgaagg ctacacaatt
    35221 tggcatggtg cgagcaaaag tggcaccacc ggatgaaata gcaggactgt tatcgccagt
    35281 cttttcttgg tagatttgca tcagtgtgct aacgagttta ctgtcttttg cgacgtatag
    35341 agacgctaga tagtcaaact cttcgtagcg gagttggtag ttttgtgcac atcttgtaag
    35401 caactctact agttcttcct tatcagttaa gacaggagtc cgaatgtcaa tacggatttc
    35461 agaacgttca tgattgatca tgagacctgc gacattaaag gataggtgac cagaaggttc
    35521 atctgctata tcaccaaaga tttgtcttcc tgtgccgtct tgacctgctt gtgttgcaag
    35581 aaagctgaga gcagggtgtt cttggagagg agcaagaatg gtagctagtc ggatgacagc
    35641 attgatacct tgactagcat ccttagcatg ctttggcact ccgagaaccg ttacggtttg
    35701 ttcagtggat tggtaatcat aaccagcttc tttgagatcg ttacaaacct gttcatagag
    35761 gggaccttgg tagttggcct tgtctggtac aacgttaaag gcgcctccta cttcaagctc
    35821 tagttgatcc gatccagggc catgaagttt gacctgtaga agcccttttt cagcataggt
    35881 cagaggaaaa gatgagtcag gtgcaaagcc catgctggcc tgttcttcga tggtattgta
    35941 gcgtgccatg cagcgccaga gggtttcctc atcggtacca aagataaagc gtacgcgctt
    36001 tttgaactga ataccttggt ccagcaagct ttttactgca tagagagctg cgagcgaagg
    36061 gcctttatca tcttggacac cacgtccgaa tacccagccg tctttgatag ttgcttcaaa
    36121 tggcggtgtc tgccaatctg cttcatcacc tgatggaaca acatccaaat gacagagaat
    36181 ggccagaagc tctgctccct gaccgatttc tgcatatccg taataacctt tagggtcaag
    36241 ataggtagtg aaacctatgt ctcgacaaat ctctaaagtt ttttctagga catcttggat
    36301 tgcttgtcca aaaggtgttc cattttctcc ttcattgagt actgaaggat aggaaatcaa
    36361 ggtttttaat gatataagaa attcatcttt aacttgattt gttatatcta ttttcatgga
    36421 atcacctcac tcactatttt ataggaatgg aaggaaggtt ccaaggagaa gaagggcgat
    36481 ggtcactaca ataatagcga ctacgagttt gcccatgaat ttccaccaag taccaatgtt
    36541 gatacgtcca agtgcaagag ctcccatcac aataccagat gttggtgcaa tcaagttcaa
    36601 gacacctgaa gcagattggt aagcagtgat aatcaagcta ggacggacat ttacaaattc
    36661 tccaagtgga gccatgatac ccatagttgc gctggcaaga ccagatgaag atgggatcaa
    36721 gaatgacata ggtagataga agatataagt tacaacgata aagacttgtg aagatagacc
    36781 gctcaagcct tctttacccc agttgaggat tgtatcggta atcataccgt cgttcatgat
    36841 aacttgaata ccacgagcaa tcgctacgat caaggcaaca ctgagcaagt cagcagcacc
    36901 attcatgaag gaagagataa tcttatcttc tttaagacca taaataacac caatcaggat
    36961 acccataaag gcaaagagca ttgcgccttc tgggaagtac caagtaccta gtgcagaagt
    37021 agatgaaccg acaatattac caataactgg aagaccagtc aaccaagcat taaagtcatc
    37081 aaaaatggta acgccaaggt ctgtccatgg aatgaagctc aataccatca agatgaatgt
    37141 caacacaaat aagaagagaa ctgatttttg tttgctgcta agtgtagatt ctacagatga
    37201 agattcttct acgttaaagt gtttcaaatc ttctttgcga gtactataaa ccagtgactt
    37261 agtcggatct ttttgaatct tatccgcata acggtaaaca aaccaagtac taagagcagt
    37321 caaggtaacc cagaagatca gacgaagtac gataccgtcc cctgtaccaa ctcccgcagt
    37381 cgctgaagca atacctgtcg caaatggatt cagagtagat gctaaacagc cgatttgaga
    37441 accgagcaaa ataattgcaa caccagtcag gctatcaaaa ccaacggcca tcataactgg
    37501 cacaaggagt ggatagaagg ccattgtttc ttcacccata ccataagttg taccaccgag
    37561 ggcaaacaaa ggcatcagta ccaaaattaa cattttttcg cggcccttat acttcttcac
    37621 gatagaggca atccctacgt caagagcacc agttttgttg acaatgccaa ggaaaccacc
    37681 aaccataagg atgaagaagg ctacatcaat cgctgcgctc gtttctttaa tgagcgaacc
    37741 ttcctctgga tgagtaccta gcatagcccg aatcggtgcc atgaggacat cccaaatccc
    37801 ttgtggattt tgaggctgag tctcgtaaat accttctata aaggcccccg cagggataaa
    37861 ccaagttagc actgccataa tagcaatgat tatcaataat acggtgtaag atgaaggcat
    37921 cttaaaccct tttttagctt tttcactcat ttgtttttcc tcctgatgtc taacaaagtg
    37981 taaaaaacca actactttct taaataaaca ttcaagaaaa cgctttctat ttatatttgt
    38041 tttaccatat taaagtctaa aactagtatc ttttgaaata ttgtacatgt tttcaagaat
    38101 aatttctaat ttgatataaa gatactagaa atagaataca tcttattagt aaaacaactt
    38161 atcctttttc aataattgtt ccgctttcag attcaatcaa ggcgcctaga ttttcaaggg
    38221 aagtaataac tgcttttcct tctggacgac cattgacaaa agcgatagct gcttctactt
    38281 ttggaagcat gctacctggt gcaaactgat cttgtttgat atattcttcc agctgggcaa
    38341 cattcacatg ttccaatttt tcctggtttg gcttgttgta gttaacaaat acataatcta
    38401 cacctgtcaa aacgatgaag aggtctgcat caaccaattc tgccaaacgt tgggaagcga
    38461 agtctttatc aataaccgct tcgacaccag tcaaatgtcc attgttttct ttgacgacgg
    38521 gaataccgcc accacctgca gctacgacga cttgaccatt atttaaaaga gtacggatgg
    38581 tttcaatttc tttgatgtca acaggttttg gtgaggcaac gaccttacgc cagccacggc
    38641 cagcatcttc cttgaaagtc gctccgctct tttcggcttc tgcttttgct tcttcttctg
    38701 aatagaaagg accgattggt ttactcaagt taacaaaagc tggatcattt ttatctacga
    38761 caacttgcgt tacaacagag gcaacatttt tttcgatgcc ttcatccaag agagcatttt
    38821 gcaaagcatt tttcaaccag aaaccgatgc taccttctgt catagcgaca agtgagtcga
    38881 gtgggaaggc agggttcttt tcagagtctg atgccaaatg ttggagcaag agattcccaa
    38941 cttgaggtcc attaccgtga gtgataatca gatcatctcc atttttaatc aattttacaa
    39001 gatgcttagc tgtttcaact aaagcttctt gttgagcctt tgctgatggg tcagaagaaa
    39061 gaatcgcatt tcctcccaaa gctactacaa ttttacgatt tgccataaat tctcctttat
    39121 cacactcaat agaatgcgtt tagatttcaa tttaatgatt tttcacatat tttataagaa
    39181 ataatagatt accattatat aaaagaggac cggactaaag ctattagtcg cagccctcat
    39241 agctgttggt agacggttta ttatctaaaa ttatacttta ggaatataaa ggttaccaag
    39301 tgtagcagcc ataacagctt tgatagtgtg catacggttt tctgcttgat cgaagtggcg
    39361 agcgtacttg ctgcggaaga cttcgtctgt tacttccatt tcttctacac caaatttttc
    39421 agcaacgtct ttaccataaa cagtgtgagt atcgtggaat gctggcaagc agtgtaggaa
    39481 gatcaagttt tcattgcctg cttttttaac taagtccata ttgacttggt aaggtttaag
    39541 aagagctaca cgttctgcga atttgtcttc ttcacccatt gatacccaaa cgtctgtgta
    39601 aagaacgtct gcatctttaa ctgcttcatc agcatcttca gtgatgagaa catgtgcgcc
    39661 actttcttta gcaaatcctt ctgctaattc aacgatttct ttttctggga agagttcttt
    39721 tggtgagaag atgtgaacat tgacaccaag gatagcacct gttacgagca agctgttggc
    39781 aacgttgtta cgtccatcac cacagtatac caatgtcaag ccttccaagc gaccgaagtt
    39841 ttcttgaaca gtcaagtagt cagcgagcat ttgagttggg tgccattcgt cagttagacc
    39901 gttccatact ggaacgcctg agaattctgc caattcttca accatacgtt ggctgaatcc
    39961 gcggaattca atcccgtcaa acatacgtcc caatacttta gcagtatctt cagtagattc
    40021 ttttttaccc aactgaatat catttgctcc gaggtattct gggtgagcac caaggtcgat
    40081 agccgcagtt gtaaaggctg cacgagtacg agtagatgtt ttttcaaata ggagagcgat
    40141 attcttgcca gcaaggtagt ggtgttgaat attgcgtttt ttcaaatctt tcaagtgagc
    40201 tgaaagacca ataaggtatt ctaactctgc acgggtaaag tctttttctg ctaagaagct
    40261 gcgtccttgg aatactgaat ttgtcatttt attatttcct ctttctattt tttacatttt
    40321 ctattgacga atgccgaaca gcgattacac ttcttcacgt tcaaatggca tagacataca
    40381 acgaggtcca ccacggcccc gaaccaattc acttccgcga atcttaatca agcgaagccc
    40441 gtattcttcc aaaatcttat tggtcacggt attgcggtca taaacaacta ccacaccagg
    40501 tgcgatggtc aaagtgttag aaccgtcgtt ccattgttca cgcgcagctg ctacgatatt
    40561 gccaccaccg caacgaatca aatgaacttt ttctacacca aggttttgag caagaagttc
    40621 agctaagtca cctttctctt caacgatttt aagtttttcg ttttcgtaag taactgagta
    40681 aacgtgaagg tcgccttcga tttctgggtg aatagtgaac ttgtcatagt ctaccatagt
    40741 gaagacagta tccaagtgca tgaatttacg gttgttagca aattcaaagg ccaaaacttt
    40801 cttgaagcca acatttttct tgaagatgtt gaccaaaagt ttttcgatag aagctgcgtc
    40861 tgtacgttga gagataccta ctgcaaggac gtctttagaa agaactaact cgtctccacc
    40921 ttcgatacgc gtatcttctt cacggttgta gaccaaatcc acttttccgc catagattgg
    40981 gtggtatttg aagatatact taccgtagag tgtttcacgg ttacgagtgt ctgcaaacat
    41041 gtggttaagc gatacggcgt ttccaattgt tgcaaatggg tcgcgagtga aatagaggtt
    41101 tggcatcggg tcaattgcaa atggataatc tgattcaact aagtcagtta gatctttagc
    41161 ttcgtcagga atttctggca attcaacttt ttgaatccca gccattgttt tttcaaccaa
    41221 ttcttggttg tccttgatgc cgtgaagcaa ttcacgaata gcaaccttgg tttgacgatc
    41281 acggatgttg gcttcgtcta agtattcctc gataaattga tcgcggattt ctggagaggt
    41341 caatgattca gcagcgagtt gttctaggta gagaacctca attccttcat cgcgaagagc
    41401 ttgggcaaat gcatcatgtt ctttttgagc atcttccaag aaaggaatat catcaaaaag
    41461 aagcctttca agatagtccg gcaacaagtt ttctaactcc ttgcctggac ggtgcaacat
    41521 aacttttttc agtttcccaa tttctgagaa gacctgaatt ggatgtgaag acatgtattt
    41581 tcctccttaa aaattttgac ttggcaccat tttgggtacc gcttacatgt atgttataac
    41641 gcaattccta ggtaatgtca atggctataa tttctcggaa aataatataa attatgatgt
    41701 ttagcacaat tttatgttat tatacataac ataggataga atacatagat acaaatgcat
    41761 aaacttctat taaagaggat ataaaatttt tttaaaaaat ttttcaaaaa atacacaaat
    41821 aaccaaaaag tgtccaatta tcatctggtt atcacttgga tctgtataaa gagaaatgtt
    41881 tgtgtgaaag gataaaaaga tgcaacattc ttttgaagat agattttgga gaagcatttc
    41941 ttgttcaatt gtacaaatta tagaatcttt tctgagtatt taggaagaga taattatctt
    42001 attgaccctc tttttatttt ttgttatagt cgacgagatg atagtttaga ataatcactt
    42061 attcacaatc tgtggaaaag tctggagagt gaatggtctt cacacaatga cctgaaagaa
    42121 gcctgagaat aattatggag agtagcattc tgagaggtgt tagcagaacc atatgacaga
    42181 gctgtttgaa gagggaatat tgaggagaaa aatcctgagc ctaccagttg gagttggaaa
    42241 gagctggcgg ttagatcatt ttttattatc cacaacctgt ggataacctt gtgaacaaga
    42301 gaagttgcta aagaaggaga tatataacga tgaagaaaat caaaccgcat ggaccgttac
    42361 caagtcagac tcagctagct tatctgggag atgaactagc agcttttatc cacttcggtc
    42421 ctaatacctt ttatgaccaa gaatggggga ctggacagga ggatcctgag cgctttaacc
    42481 cgagtcagtt ggatgcgcgt gagtgggttc gtgtgctcaa ggaaacgggc ttcaaaaagt
    42541 tgattttggt ggtcaagcac cacgatggct ttgtccttta tccgacagct cacacagatt
    42601 attcggttaa ggtcagtcct tggaggagag gaaagggcga cttgctcctt gaagtatccc
    42661 aagctgccac agagtttgat atggatatgg gggtctacct gtcaccgtgg gatgcccata
    42721 gtcccctcta tcatgtggac cgagaagcgg actacaatgc ctattatctg gctcagctga
    42781 aggaaatctt atcaaatcct gcctatggaa atggagggaa atttgctgag gtttggatgg
    42841 atggtgccag aggagagggc gcgcaaaagg ttaattatga atttgaaaaa tggtttgaaa
    42901 ccattcgtga cctgcagggc aattgcttga ttttttcaac agaaggcacc agtatccgat
    42961 ggattggcaa tgaacgaggg tatgcaggtg atccactgtg gcaaaaggtg aatcctgata
    43021 aactaggaac agaagcagag ctggactatc ttcagcacgg ggatccctcg ggcacgattt
    43081 tttcaatcgg agaggcagat gtttccatcc gtccaggctg gttctaccat gaggatcagg
    43141 atcctaagtc tctcgaggag ttggtcgaaa tctactttca ctcagtaggg cgaggaactc
    43201 cactcttgct taatattccg ccgaatcaag ctgggctctt tgatgcaaag gatattgaac
    43261 gactttatga atttgcgacc tatcgcaatg agctctataa agaagatttg gctctgggag
    43321 ctgaggtatc tggtccagct ctttccgcag actttgcttg tcgccatttg acagacggcc
    43381 ttgagaccag ctcttgggca agcgatgcag acttgcccat ccagttagaa ctcgacttag
    43441 gttctcctaa aacttttgat gtaattgagt tgagagaaga tttgaagtta ggccaacgta
    43501 tttctgcttt ccatgtgcaa gtagaggtgg atggtgtctg gcaggaattt ggcaggggct
    43561 tcacagttgg tcataagcgc ctcttgcgag gagcagttgt tgaagcacag aagatacgtg
    43621 tagtcattac agaatcacag gctttgcctt tgttgaccaa gatttcactc tataaaactc
    43681 cgaggttatc acaaacagta gctgttcagg ggctagcatt tgcagaaaaa agcctagctg
    43741 tggcaaaggg agagactctt cattttagga ttgaacgtag tgaaagtagc tcctctttag
    43801 aggctaagat ttcgattcaa ccggggacag gtgtccatgg tgtcgcctat caggatgaga
    43861 ttcaagtcct tcaattccaa gcaggggaaa gcaaaaaaga tttgcatcta ccaaccctgt
    43921 atttcgcagg agataaaacc ttggatttct atctgaacct aacggtggat ggtcagcttg
    43981 tggatcaact tcaagtccaa gtttcataaa agaagaacct ttgcgcgatg caaaggttct
    44041 tttggttatt agtgatttgg tagccagctg agggtgaaag ttagttgttc agcttttagg
    44101 aggtcttggt gttgaatagt tgatacgagt gttttgtcca gtcggcattc tttgacaaag
    44161 ttaaaatggc tgtggttttg ctcagtatga atatctagcc atttattttc tttagctagg
    44221 tagactcgta gatggtcaaa gagaggaatt ccgagatcat agcttggttt tcctggacag
    44281 gttggataaa atccgagagc tgaccagatg taccaagcag agagactacc attgtcttca
    44341 tctccaggat aggcttccca acttgggtga aaagctttct gacggagcgt cttgataaga
    44401 agggcagtgt agtcagggta atcgctgtag cggaagagat aaggaatgtg gaaactaggc
    44461 tggttggaaa tggctatttg tccaaaagga gcagtagcca tctcgctcat ttcgtgaatt
    44521 tcgtaaccat agcctgttgt ttcaaagagg ggagcatctt gacaggcttt caaaagatag
    44581 ttgctaaagg tttcttttcc acccatcagt tggattaagc cagggatgtc gtggagaacg
    44641 cctaaagtag cttgaatggc agagcattca gcgtagtctc gcccccaact ataaggagag
    44701 aagtcagggt gaaagtttcc ttgattgtct cgtgctcgca tgtaacctgt ctcagcgtca
    44761 aatagctggc ggtaattttg tgaagcagcc ttgtaggttt cagcgatttc tatgtttttt
    44821 agttttttgg cacagttggc gatacaaaag tcactatagg catagtctag agtatggcta
    44881 acactttcgt ggtggtcggt agagaggtaa cctagttctt ggtattgggc tagtccgtgg
    44941 cggccattga tgccgagagg gtcggctttg ctggctgttt tgagcatggc ttggaagagt
    45001 tctccttcta ggtcgggggc catgtccttg caggcgctat ctgcgataat accgtctaaa
    45061 agtgtacctg gcatcatacc ccgttcatct ggagccagcc attttggaag gaaaccagta
    45121 tcgcggtagc tattgaggaa accttctaaa aagcgttgat agtgctccgg tatgataagg
    45181 gcaaagaggg ggaaggtggt gcggaaggta tcccagaaac cattgttgct aaagaggaca
    45241 ccaggcttga cagtaccagt agccagatcc atgtggatgg cttgccctga ctcatcaacc
    45301 tcataaaaag tctgtgggaa gaggaagagt ctgtagagac agtggtcaaa gaaggttcgg
    45361 ttagcctctc ctgtctctat aacatcaaaa cgatggagga gattttccca atccgcttgg
    45421 gcacttgctt tacagctatc aaaatcttct tgaggtagat tgattagagc ttgagaagga
    45481 gagatgaaag aagtggctag ttgcatctcg gtttgactac ttgctaagtc aattcgccag
    45541 tctccagctt cttggctgat agcaagaata tccgtgttca tttgcagggc agtgaacatc
    45601 gttagcgaat ttttgttggt ttcagtttta ccttcttgtc gcagggcaag agttcgctta
    45661 tctacttgct ctactgtcag ttcatctgct gcgtgaagat agagggagag ggctttgcct
    45721 tgcttttgct tcaaacgaat agaagcaccg tagcaagtcg gtgtgagctg ggtttcaatt
    45781 tgatagcgca gggagaaaat ctttagataa tgaggttgga aagaggcctt atccctatca
    45841 taggaagatt ggcggtgaaa gagactgtct cccccaagct gacctgtgac aggtgtcaga
    45901 aggagccaag agtagtcccc aatccaagga ctgggctggt gagttaatcg aatcccctga
    45961 aagataggca gatgcggatc gaagaaccaa gatccatcct ggtcactggt ctggggcaca
    46021 aagtaattca tcccaaaagg cacgcctgtg tatggcaggg tatttccccg agaaaaggca
    46081 tgcttgttgg tagttcccaa gcgggtatcg atggtttcaa gtagtggttt catagtcttt
    46141 cctttagctg tttttctaca ttatatcaga aaaagagggc ctttagaaaa ggagtttcaa
    46201 agataactat tttgtagaaa aatgactatc atttgtgtat gtattttctg tctcaaaagc
    46261 tatatactga aaatgaaact tgtttgaaag agggaattgc acgatgattt attcgaaaga
    46321 aattgttaga gaatggctag atgaagtagc agagcgggct aaggaccatc cagagtgggt
    46381 ggatgttttc gagcgttgct acaccgatac cttggacaat acggttgaaa tcttagaaga
    46441 tggttcaact tttgtcttga ctggggatat tcctgccatg tggcttcgag attcgacagc
    46501 ccaactcaga ccctaccttc atgtagctaa aagagatgcc ctcctgcgtc agaccattgc
    46561 aggtttggtc aaacgtcaga tgaccttggt actcaaggat ccctatgcta actccttcaa
    46621 cattgagaag aactggaaag ggcaccacga gactgaccac acagacctta acggctggat
    46681 ctgggagcgc aagtatgagg tggattcact ttgctatcct ttgcagttgg cttatctcct
    46741 ctggaaagag actggcgaga ctggtcagtt tgatgagact tttgtcgcag cgactaagga
    46801 aattctccat ctatggacag ttgaacaaga ccacaagaac tctccttatc gttttgtccg
    46861 agatacggac cgtaaggaag acaccttggt aaatgatggc tttggacctg actttgcagt
    46921 gacaggtatg acttggtcag cttttcgtcc gagtgacgat tgctgtcagt atagttactt
    46981 gattccgtct aatatgtttg ccgtagtagt cttgggttat gtgcaagaaa tctttgtcga
    47041 attagaccta gctgatagcc agagtgttat tgctgatgcc aagcgtcttc aggatgaaat
    47101 ccaagaagga atcgaaaact acgcttacac caccaacagc aagggcgaaa agatttacgc
    47161 ttttgaagta gatggcctag gaaatgccag catcatggat gatccaaatg taccaagtct
    47221 actagctgcg ccctatctgg gctactgttc gatcgatgat gaagtgtatc aagccactcg
    47281 ccgtaccatt ctgagctctg aaaatccata cttctaccaa ggagaatacg ctagcggtct
    47341 cggaagttct cataccttct atcgctatat ctggccaatc gccctttcta tccaaggatt
    47401 gacaacaaga gataaggcag agaaaaaatt cttgctggat cagctggttg cctgcgatgg
    47461 tggtacaggt gtcatgcacg aaagcttcca cgtagatgat ccgaccctct actctcgtga
    47521 atggttctcc tgggctaaca tgatgttctg tgagttggtc ttggattact tggatattcg
    47581 ctaaggggct cgctttagct caaccgattc ttatcagaat cacaagttta catttaaaac
    47641 gttaaaattt aaatttagaa tgaggtttta cttcatggaa aatgttgttg tacatattat
    47701 ctcacatagt cactgggacc gtgagtggta cttgcctttt gaaagccatc gtatgcagtt
    47761 ggtggaattg tttgacaatc tctttgatct ctttgaaaat gaccctgagt tcaagagttt
    47821 ccacttggat ggacaaacta ttgtccttga tgactactta caaattcgcc ctgaaaatcg
    47881 cgacaaggtc caacgctaca ttgacgaggg caaacttaaa attggtccct tttacatctt
    47941 gcaggatgac tacttgatct ccagtgaagc caatgtccgc aataccttga ttggtcaaca
    48001 agaagctgcc aaatggggta aatcaaccca gattggctac tttccagata cctttggaaa
    48061 tatgggacaa gcgcctcaaa ttcttcaaaa atcaggcatt cacgtggcgg cctttggtcg
    48121 tggtgtgaag ccgattggat ttgacaacca agtccttgaa gatgagcagt ttacatccca
    48181 gttttcagaa atgtactggc agggtgtgga tggtagtcgt gttttaggta ttctctttgc
    48241 caactggtac agtaatggga atgaaatccc agttgacaaa gatgaggcct tgaccttctg
    48301 gaaacaaaaa ttgtcagatg tgcgtgccta cgcttcgacc aaccaatggt tgatgatgaa
    48361 cggctgtgac caccagcctg tacagaaaaa tctgagcgaa gccattcgtg tggcaaatga
    48421 actcttcccg gatgtaatct ttgttcatag ttcttttgat gaatatgttc aagctgtaga
    48481 aggtgcgctt cctgaacact tatcaactgt tacaggcgag ttgaccagtc aggaaacaga
    48541 tggctggtac acacttgcca acacttcttc atcccgcatt tacctaaaac aagccttcca
    48601 agaaaatagc aacctcctag agcaagtggt agaacccttg actattatca ctggtggaca
    48661 caaccacaag gaccagttga cctatgcttg gaaaacactt ttgcagaatg cgccacatga
    48721 tagtatctgt ggctgtagcg tggacgaagt tcaccgcgag atggaaacgc gttttgccaa
    48781 ggtcaaccaa gtaggaaact ttgttaaaag taacttgctc aacgagtgga agggtaaaat
    48841 tgctacggat aaggctcaaa gtgactatct ctttactgtc attaacacag gcttgcatga
    48901 taaggtcgat actgtcagca cagtgattga tgtggcgact tgtgatttca aggtattgca
    48961 cccaacagaa ggctacaaaa agatggctgc tcttatcttg ccaagttacc gtgtggagga
    49021 cttggatggt catcctgtag aggctacaat cgaagacctc ggagctaatt ttgagtatga
    49081 tttaccaaaa gacaagttcc gccaagctcg tattgctcgt caagtgcgcg tgaccattcc
    49141 agttcaccta gcgccgcttt cttggacaac cttccaattg ctggaaggaa aacaagaaca
    49201 ccgtgagggt atttaccaaa acggagtgat tgatacacca ttcgtaacgg tgagtgtgga
    49261 tgacaacatc acagtctatg acaagacaac tcacgaagcc tatgaagact ttatccgctt
    49321 tgaagaccgt ggggacatcg gaaacgagta tatctatttc caaccaaaag gaacagagcc
    49381 aatctttgca gaacttaagg gccacgaggt cttggaaaac acagcttgct atgctaaaat
    49441 cttgctcaaa catgaattga ccgtgcctgt cagcgcggat gaaaagctag aagaagagca
    49501 acaaggtatc atcgagttta tgaagcgtga ggctggacgg tcagaagaat tgacaaacat
    49561 tcctctggaa actgagttga ctgtcttcgt tgacaatcca caaatccgct tcaagactcg
    49621 ctttactaac actgccaagg atcaccgtat ccgtctcttg gtcaagactc ataacacgcg
    49681 tccaagcaat gattctgaaa gtatctatga ggtggtgaca cgaccaaaca aaccagctgc
    49741 ttcatgggaa aatcctgaaa atcctcaaca ccaacaagct tttgtcagtc tgtatgacga
    49801 tgaaaaaggg gtgactgtat ccaataaggg attgaatgaa tacgaaatcc ttggggataa
    49861 caccattgcc gtgaccattt tgcgtgcatc aggtgagcta ggtgactggg gctacttccc
    49921 aacgccagaa gcacaatgct tgcgtgagtt tgaagtcgag tttgcacttg aatgccacca
    49981 agcccaagaa cgcttctcag cctatcgtcg tgccaaagcc ttgcagacac cgtttaccag
    50041 ccttcagctt gctagacagg aaggaagcgt ggttgcgact ggtagcctct tgagccattc
    50101 tgttctcagc ataccgcaag tttgtccaac agcctttaaa gtggcggaaa atgaagaagg
    50161 ctatgtcctc cgttactata atatgagtca agaaaatgtg cgcatatcag aacatcaaca
    50221 aaccattctt gacttacttg agcgaccata tccagttcat tcaggactat tggctccaca
    50281 agagattcgt acagaattca tcaaaaaaga agaaatttaa tttcaaaaag taaacatcaa
    50341 aagaaaggag gggcgaaaaa gtaagaacta actgctgatt cgcccctttt tatggtaaaa
    50401 acaatgacca ttgcaacgat tgatatcgga gggactggga ttaagtttgc cagtctgact
    50461 cctgatggga aaatactgta taagacaagt atttcaacgc ctgaaaactt ggaggattta
    50521 ctagcgtggc tagatcaacg cttgtcagaa caggattaca gtgggattgc tatgagcgtt
    50581 ccaggtgcgg tcaatcaaga gacaggtgtg attgatggct tcagtgcggt gccctacatc
    50641 catggctttt cttggtatga ggcgcttagc tcttatcagc tacctgtcca tttagaaaat
    50701 gatgccaact gcgttggact cagtgaacta ctagctcatc cagagcttga aaatgcagcc
    50761 tgtgtcgtga ttgggacagg gattggcgga gccatgatta tcaatggtag acttcatcga
    50821 ggtcgccacg gtctgggtgg agaatttggc tacatgacaa cccttgcccc tgctgaaaaa
    50881 cttaataact ggtcgcaact agcatcaact gggaatatgg tacgatacgt gattgaaaaa
    50941 tctggtcata ctgattggga cggtcgcaag atttaccaag aggccgcagc tggtaatgct
    51001 ctttgtcaag aagccattga gcgcatgaac cgcaatctga cgcaaggctt gctcaatatc
    51061 cagtatctga tcgatccaga tgtcatcagt ctgggtggct ctatcagtca aaatccagat
    51121 tttatccaag gtgttaagaa ggctgttgaa gactttgtcg atgcctacga agaatacacg
    51181 gtcgcaccag ttatccagac ctgcacctat cacgcagatg ccaatctcta cggtgccctt
    51241 gtcaactggc tacaggagga aaagcaatgg taagatttac aggacttagt cccaaacaaa
    51301 cgcaagctat tgaggtttta aaaggtcata tttctctacc agatgtggaa gtggctgtca
    51361 ctcagtctga ccaagcctct atctctatcg agggtgagga aggtcactat caattgacct
    51421 accgcaaacc tcaccaactt tatcgtgcct tatccttgtt ggtaacagtt ctagcagaag
    51481 ctgataaagt agagattgag gaacaagcag cttacgaaga tttggcttac atggttgact
    51541 gttctcgaaa tgcggtgctg aatgtggctt ctgccaagca gatgattgag gtcttggctc
    51601 tcatgggcta ctcaaccttt gagctttaca tggaagacac ttaccagatt gaaggacagc
    51661 cttactttgg ctatttccgt ggagcttatt cagcagagga gttgcaggaa atcgaagcct
    51721 atgcccaaca gtttgacatg acctttgtac catgcatcca gaccttggcc cacttgtcgg
    51781 cctttgtcaa atggggtgtc aaggaagtcc aggagctccg tgatgtagag gacattcttc
    51841 tcattggcga agaaaaggtt tatgacctga ttgatggcat gtttgccacg ttgtctaaac
    51901 tgaagactcg caaggtcaat atcgggatgg acgaagccca cttggttggt ttgggacgct
    51961 acctgatttt gaacggtgtt gtggatcgta gtctcctcat gtgccaacac ttggagcgcg
    52021 tgctggatat tgctgacaaa tatggtttcc actgccagat gtggagtgat atgttcttca
    52081 aactcatgtc agcggatggc cagtacgacc gtgatgtgga aattccagag gaaactcgtg
    52141 tctacctaga ccgtctcaaa gaccgtgtga ctctggttta ctgggattat tatcaggata
    52201 gcgaggaaaa atacaaccgt aatttccgca atcatcacaa gattagccat gaccttgcat
    52261 ttgcaggggg agcttggaag tggattggct ttacacctca caaccatttt agccgtctag
    52321 tgactatcga ggctaataaa gcctgccgtg ccaatcagat taaagaagtc atcgtaactg
    52381 gttggggaga caatggtggt gaaactgccc agttctctat cctaccaagc ttgcaaatct
    52441 gggcagaact cagctatcgc aatgacctag atagtttgtc tgcgcacttc aagaccaata
    52501 ctggtctaac ggttgaggat tttatgcaga ttgatcttgc caacctctta ccagacctac
    52561 caggcaatct cagcggtatc aatcccaacc gctatgtttt ttatcaggat attctttgtc
    52621 cgattcttga tcaacacatg acacctgaac aggacaaacc gcacttcgct caggctgctg
    52681 agacgcttgc taacattaaa gaaaaagctg gaaactatgc ttatctcttt gaaactcagg
    52741 cccagttgaa tgctatttta agtagcaaag tagatgtggg acgacgcatt cgtcatgcct
    52801 accaagcgga tgataaagaa agtttacaac aaatcgccag acaagaatta ccagaactta
    52861 gaagccaaat tgaagacttc catgccctct ttagccacca atggctgaaa gaaaacaagg
    52921 tctttggttt ggatacagtt gacatccgta tgggcggact cttgcaacgc atcaaacgag
    52981 cagaaagccg tatcgaggtt tatctggctg gtcagcttga ccgcatcgac gagctggaag
    53041 ttgaaatcct accatttact gacttctacg cagacaagga cttcgcagca actacagcta
    53101 accagtggca taccattgcg acagcgtcga cgatttatac gacttaatac tcttcgaaaa
    53161 tctcttcaaa ccacgtcagc ttccatctac aacctcaaaa cagtgttttg agcagcctgc
    53221 agctagcttc ctagtttgct ctttgatttt cattgagtat aaaaacaaga acaccttgct
    53281 tggcgcaggg tgtttcgcgt gaaacagaag aattatctgg tttcaaatgc tacagttaga
    53341 caaacttatg ataaaatagc agaaagtgaa tgtttcctaa gagcaattct atcgatgagc
    53401 aattggaggt attatgctac acttaaaatt agtaaaacaa gaaatagaag cttgggtcat
    53461 ttccgtcaaa tttaaaaaag gttgctaccg acatatatag attccaaaaa caaaaacgtt
    53521 agcgaaacta gcagatgtga ttttatggag ttttgatttt gcaaatgatc atgctcacgc
    53581 atttttcatg gataatgttg agtggagtca tgcagattct tactttttta gctttgttag
    53641 tgacgatgtt gaagaacgtt acacagaaaa tgtctatctg gatagcctaa gtgtcaaaca
    53701 aaaatttaag tttattttcg acttcggtga tgaatggcgt tttgaatgcc aagtgctgag
    53761 agaaatcgag acagaggacg aagaagctta tctcgtacgt tcggttggaa cgtcgccaga
    53821 acaatatcca gattatgatg gttttgacta tgaagaatgg taaaattgaa atcagtctgt
    53881 gtaggcttag tatttcaata gacttcctgc aaaactagaa tcctagttca tgattgataa
    53941 taccagcact caaattcatt cgtaatccga agcgtttacg atgatttcga taggttgttg
    54001 aaattatttt aaacgttttt actttggcaa agatgttctc aaccttgctt ctctccttgg
    54061 atagcgcatg gttacaggct ttatcttcaa ctgttagcgg cttgagtttg ctggatttac
    54121 gtggagtttg tgcttgagga tatatcttca tgagcccttg ataaccactg tcagccaaga
    54181 ttttaccagc ttgtccgata tttctgcaac tcattttgaa caacttcata tcatgacaat
    54241 agttcacagt gatatccaaa gaaacaattc tcccttgact tgtgacaatc gcttgagcct
    54301 tcatagcgtg aaatttcttt ttaccagaat cattcgctaa ttgttttttt agggcgattg
    54361 atttttactt ccgtcgcatc aatcattacc gtgtcctcag aactgagagg agttcttgaa
    54421 accgtaaaac cactttgaac aagagttact tcaacccatt ggctccgacg gataaagttg
    54481 ctttcgtgaa taccaaaatc agccgcaatt tcttcataag ttcgatattc tcgcactatt
    54541 gaagagtggg cataagaagg tcttctaggc ttaatttagg ttttcgtcca ccttttgcgt
    54601 gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtc gtgcgttgaa
    54661 caccaacaag acgcttaaat cgtgcatcgg ttagttgttt acttgcttca taattttgtt
    54721 tcgcagggag tctattgact ctttggtagg tgtcaatgtt tttttcatct atcccgagaa
    54781 ttattttccc gccatttgta tttgcaaatg ctgagtaggt ttcccagaaa gactctggaa
    54841 gattgttttt agcttttttg tattctaaat caaccccttc aaattttaag tccatatttt
    54901 tcctttacat ctgttttttg tggttctggt atttgttcaa gttgagtgat aatatagcga
    54961 attgaatttc gagagttttt actcagttaa tttctttttt aacccacttt aatttctttt
    55021 ttaacacggg ttaaaaaaga aattaaagtg ggttaatttt ccttgactta aaatttaaaa
    55081 atgatatact gtgtttatgg agagatgaca atttataaaa tgtactactc tattctacta
    55141 gataatgatt gaataaaact ttttataaca acggctagca aagttataat tttatatcta
    55201 ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac tacaatatta tcattaacta
    55261 cagctgcggt tattttagca gcatatgtcc ctaatgaacc aatcctagca gatactccta
    55321 gttcggaagt aatcaaagag actaaagttg gaagtattat tcaacaaaat aatatcaaat
    55381 ataaggttct aactgtagaa ggtaacatag gaactgttca agtgggtaat ggagttactc
    55441 ctgtagagtt tgaagctggt caagatggaa aaccattcac gattcctaca aaaatcacag
    55501 taggtgataa agtatttacc gttactgaag tagctagtca agcttttagt tattatccag
    55561 atgaaacagg tagaattgtc tactatccta gctctattac tatcccatca agcataaaaa
    55621 aaatacaaaa aaaaggcttc catggaagta aagctaaaac tattattttt gacaaaggca
    55681 gtcagctgga gaaaattgaa gatagagctt ttgatttttc tgaattagaa gagattgaat
    55741 tgcctgcatc tctagaatat attggaacaa gtgcattttc ttttagtcaa aaattgaaaa
    55801 agctaacctt ttcctcaagt tcaaaattag aattaatatc acatgaggct tttgctaatt
    55861 tatcaaattt agagaaacta acattaccaa aatcggttaa aacattagga agtaatctat
    55921 ttagactcac tactagctta aaacatgttg atgttgaaga aggaaatgaa tcgtttgcct
    55981 cagttgatgg tgttttgttt tcaaaagata aaactcaatt aatttattat ccaagtcaaa
    56041 aaaatgacga aagttataaa acgcctaagg agacaaaaga acttgcatca tattcgttta
    56101 ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg tttagaaaaa atcggtactt
    56161 ttgcatttgc ggatgcgatt aaacttgaag aaattagctt accaaatagt ttagaaacta
    56221 ttgaacgttt agccttttac ggtaatttag aattaaaaga acttatatta ccagataatg
    56281 ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa attaaaaagt ttaacaattg
    56341 gtaataatat caactcattg ccgtccttct tcctaagtgg cgtcttagat tcattaaagg
    56401 aaattcatat taagaataaa agtacagagt tttctgtgaa aaaagataca tttgcaattc
    56461 ctgaaactgt taagttctat gtaacatcag aacatataaa agatgttctt aaatcaaatt
    56521 tatctactag taatgatatc attgttgaaa aagtagataa tataaaacaa gagactgatg
    56581 tagctaaacc taaaaagaat tctaatcagg gagtag
//
LOCUS       DAVLZG010000004        54157 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLZG010000004 DAVLZG010000000
VERSION     DAVLZG010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.004"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            174..512
                     /locus_tag="VYO72_000258"
     CDS             174..512
                     /locus_tag="VYO72_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV1706703.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            702..2138
                     /locus_tag="VYO72_000259"
     CDS             702..2138
                     /locus_tag="VYO72_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1706704.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2190..2429
                     /locus_tag="VYO72_000260"
     CDS             2190..2429
                     /locus_tag="VYO72_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV1706705.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2559..2873
                     /locus_tag="VYO72_000261"
     CDS             2559..2873
                     /locus_tag="VYO72_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV1706706.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2991..4970
                     /locus_tag="VYO72_000262"
     CDS             2991..4970
                     /locus_tag="VYO72_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1706707.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            4980..5294
                     /locus_tag="VYO72_000263"
     CDS             4980..5294
                     /locus_tag="VYO72_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV1706708.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5325..5831
                     /locus_tag="VYO72_000264"
     CDS             5325..5831
                     /locus_tag="VYO72_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706709.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFENLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5911..7257
                     /gene="celB"
                     /locus_tag="VYO72_000265"
     CDS             5911..7257
                     /gene="celB"
                     /locus_tag="VYO72_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV1706710.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNSLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7637..7813
                     /locus_tag="VYO72_000266"
     CDS             7637..7813
                     /locus_tag="VYO72_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706711.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALSLGMT"
     gene            8215..10428
                     /locus_tag="VYO72_000267"
     CDS             8215..10428
                     /locus_tag="VYO72_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1706712.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEDEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10650..11126)
                     /locus_tag="VYO72_000268"
     CDS             complement(10650..11126)
                     /locus_tag="VYO72_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1706713.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTNPKQIEEAIQTLL"
     gene            11349..14552
                     /locus_tag="VYO72_000269"
     CDS             11349..14552
                     /locus_tag="VYO72_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1706714.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSTWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDIASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKSGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14932..15317
                     /gene="tnpA"
                     /locus_tag="VYO72_000270"
                     /pseudo
     CDS             14932..15317
                     /gene="tnpA"
                     /locus_tag="VYO72_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15696..16325)
                     /locus_tag="VYO72_000271"
     CDS             complement(15696..16325)
                     /locus_tag="VYO72_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1706715.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16335..17336)
                     /locus_tag="VYO72_000272"
     CDS             complement(16335..17336)
                     /locus_tag="VYO72_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1706716.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17367..18008)
                     /locus_tag="VYO72_000273"
     CDS             complement(17367..18008)
                     /locus_tag="VYO72_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1706717.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18027..18842)
                     /locus_tag="VYO72_000274"
     CDS             complement(18027..18842)
                     /locus_tag="VYO72_000274"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1706718.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19113..19547
                     /locus_tag="VYO72_000275"
     CDS             19113..19547
                     /locus_tag="VYO72_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1706719.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAARGGVVNGKELFSTDAEEEEEDFESGI"
     gene            19559..20749
                     /locus_tag="VYO72_000276"
     CDS             19559..20749
                     /locus_tag="VYO72_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1706720.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20760..21251
                     /locus_tag="VYO72_000277"
     CDS             20760..21251
                     /locus_tag="VYO72_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1706721.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21266..22045
                     /locus_tag="VYO72_000278"
     CDS             21266..22045
                     /locus_tag="VYO72_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1706722.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            22032..22850
                     /locus_tag="VYO72_000279"
     CDS             22032..22850
                     /locus_tag="VYO72_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1706723.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEVFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            22850..23143
                     /locus_tag="VYO72_000280"
     CDS             22850..23143
                     /locus_tag="VYO72_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1706724.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23165..25066
                     /locus_tag="VYO72_000281"
     CDS             23165..25066
                     /locus_tag="VYO72_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1706725.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25126..26127
                     /locus_tag="VYO72_000282"
     CDS             25126..26127
                     /locus_tag="VYO72_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1706726.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKKLNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26237..26572)
                     /locus_tag="VYO72_000283"
     CDS             complement(26237..26572)
                     /locus_tag="VYO72_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706727.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26583..26825)
                     /locus_tag="VYO72_000284"
     CDS             complement(26583..26825)
                     /locus_tag="VYO72_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706728.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(26841..27035)
                     /locus_tag="VYO72_000285"
     CDS             complement(26841..27035)
                     /locus_tag="VYO72_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1706729.1"
                     /translation="MNRVKEFRKELGISQLELAKNIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27201..28151
                     /gene="rsmH"
                     /locus_tag="VYO72_000286"
     CDS             27201..28151
                     /gene="rsmH"
                     /locus_tag="VYO72_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1706730.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DRKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            28163..28480
                     /gene="ftsL"
                     /locus_tag="VYO72_000287"
     CDS             28163..28480
                     /gene="ftsL"
                     /locus_tag="VYO72_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1706731.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            28484..30736
                     /gene="pbpX"
                     /locus_tag="VYO72_000288"
     CDS             28484..30736
                     /gene="pbpX"
                     /locus_tag="VYO72_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1706732.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            30738..31718
                     /locus_tag="VYO72_000289"
     CDS             30738..31718
                     /locus_tag="VYO72_000289"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1706733.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            32281..34386
                     /locus_tag="VYO72_000290"
     CDS             32281..34386
                     /locus_tag="VYO72_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1706734.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(34682..35164)
                     /locus_tag="VYO72_000291"
     CDS             complement(34682..35164)
                     /locus_tag="VYO72_000291"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1706735.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(35259..36743)
                     /locus_tag="VYO72_000292"
     CDS             complement(35259..36743)
                     /locus_tag="VYO72_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1706736.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMSERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            36896..38503
                     /locus_tag="VYO72_000293"
     CDS             36896..38503
                     /locus_tag="VYO72_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1706737.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            38668..38835
                     /locus_tag="VYO72_000294"
     CDS             38668..38835
                     /locus_tag="VYO72_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV1706738.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(38828..39678)
                     /locus_tag="VYO72_000295"
                     /pseudo
     CDS             complement(38828..39678)
                     /locus_tag="VYO72_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            39931..41376
                     /gene="cps4A"
                     /locus_tag="VYO72_000296"
     CDS             39931..41376
                     /gene="cps4A"
                     /locus_tag="VYO72_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV1706739.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            41378..42109
                     /gene="cps4B"
                     /locus_tag="VYO72_000297"
     CDS             41378..42109
                     /gene="cps4B"
                     /locus_tag="VYO72_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV1706740.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            42118..42810
                     /gene="cpsC"
                     /locus_tag="VYO72_000298"
     CDS             42118..42810
                     /gene="cpsC"
                     /locus_tag="VYO72_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV1706741.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            42820..43509
                     /locus_tag="VYO72_000299"
     CDS             42820..43509
                     /locus_tag="VYO72_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1706742.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            43525..44892
                     /locus_tag="VYO72_000300"
     CDS             43525..44892
                     /locus_tag="VYO72_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1706743.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            44923..46095
                     /locus_tag="VYO72_000301"
     CDS             44923..46095
                     /locus_tag="VYO72_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1706744.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            46092..47375
                     /locus_tag="VYO72_000302"
     CDS             46092..47375
                     /locus_tag="VYO72_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1706745.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            47353..48042
                     /locus_tag="VYO72_000303"
     CDS             47353..48042
                     /locus_tag="VYO72_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEV1706746.1"
                     /translation="MIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSRGLLRG
                     IGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVKIGDYS
                     QIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAENHSYEV
                     LHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPDNVIIG
                     GVPAKILMERK"
     gene            48086..49321
                     /locus_tag="VYO72_000304"
     CDS             48086..49321
                     /locus_tag="VYO72_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1706747.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            49272..50453
                     /locus_tag="VYO72_000305"
     CDS             49272..50453
                     /locus_tag="VYO72_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1706748.1"
                     /translation="MTLRIKYIHEIFLEEIDKNMKKVLIVRSGPYQVNPEGYNLQELG
                     LASAISQQGYQCDVMYYHKTKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKF
                     LNQYDKIIISEYSQIMAVLLSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKR
                     TKTVFCKTEKAECYLKNKGFNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNI
                     LYVGSLSKRKNTAQLIRIFNILKSKSGKKNELQLVLIGKDEDNIVEKINYSRFKDDII
                     YQPYLKNSQLQFIYPSSQLLVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDG
                     INGKIVNDFNDEHWVDCIENLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDE
                     R"
     gene            50462..51304
                     /locus_tag="VYO72_000306"
     CDS             50462..51304
                     /locus_tag="VYO72_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1706749.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            51346..52614
                     /locus_tag="VYO72_000307"
     CDS             51346..52614
                     /locus_tag="VYO72_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV1706750.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            52607..53614
                     /locus_tag="VYO72_000308"
     CDS             52607..53614
                     /locus_tag="VYO72_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706751.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            53619..>54157
                     /locus_tag="VYO72_000309"
     CDS             53619..>54157
                     /locus_tag="VYO72_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEV1706752.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISS"
BASE COUNT        17177 a         8826 c        11543 g        16611 t
ORIGIN      
        1 tgctcttgtt tcaattgact ataaatcgct ataagaaaaa atcattttat tggtataaag
       61 aagtgattga aagtaatggc gaaacgttag ataattagtt cataaaaaac aagtttagat
      121 cctcatctaa acttgttttt ttaaaattga aggatgattt tggaggatat aagatgacat
      181 tgactattca tgtatattat aaaggtgatg gagatagtgc aataaagttt gcaagagaaa
      241 tgcttgatag tggccttgtt aaagaaatta gaaatcaaaa aggtaacttg aaatacgaat
      301 attttttacc aattgaaaaa gagggaacta ttctccttat tgatcagtgg ataaatcaag
      361 aaactttaga taaacattat caatcaaaga caatgcagaa aatcttagat ttaagaaaaa
      421 aatatcactt gcagatgcaa gttgaacgtt atatagaaga tgattctggg atgccagaaa
      481 gcgataagtc gtttatagac acagggaatt agaattattg tgagagtttt tgtagtttga
      541 aagtattgaa aatcgtaaag atatcattac gagaatacaa gaagatattg ttctatttcc
      601 attaaaaatt acttctttcc ttaacaataa ggaaaaagaa tgcgttttca tcttttggtt
      661 taaggtttat aataagagta tcaaagtcag gaggaaaaaa gatgactact tttaaagatg
      721 gatttttatg gggtggtgct gttgctgctc atcaacttga aggtggatgg caagaaggtg
      781 gcaagggaat tagtgttgct gatgttatga ctgctggtcg tcatggagta gctcgtgaaa
      841 ttactttggg agttttagag ggtaaatatt atccaaatca tgaggcgata gatttttatc
      901 atcgttataa agaagacata gcactttttg ctgaaatggg attcaagtgc ttccgtacct
      961 ctattgcatg gacacgtatc tttccaaaag gtgatgagtt agagccgaat gaagaaggat
     1021 tacagtttta tgataatctt tttgatgaat gcttaaagaa tggtattgaa cctgtcatca
     1081 ctctatctca ttttgaaatg ccttatcact tagtgaccga atatggtggt tggaaaaata
     1141 ggaaattgat tgatttcttt gctcgttttg cagaagtcgt atttaaacgt tacaaagata
     1201 aggttaaata ttggatgact ttcaatgaaa tcaataatca agcgaattat caggaagatt
     1261 ttgcaccatt tactaactca ggtattgtat atgaggaagg tgataataga gaagcaatta
     1321 tgtatcaagc agcacattac gaattagttg cttctgcacg agctgtaaaa attggtcatg
     1381 agattaatcc agattttcaa ataggttgta tgattgcgat gtgtccaatt tatccagtta
     1441 cttgcaatcc taaggatatc ttaatggcaa tgaaagctat gcagaagcgt tattattttg
     1501 ctgatgtgca tgttttaggt aaatatcctg agcatatttt caagtattgg gaacgaaaag
     1561 gtatttcagt tgattttact gaccaggata aagaagattt acttggtggg actgtagatt
     1621 acattggttt cagttactat atgtcctttg ctatagactc tcatcgtgaa aataatcctt
     1681 attttgatta tcttgaaaca gaagatttag tgaaaaataa ttatgttaag gcttctgaat
     1741 gggagtggca aattgatcca gaaggtttac gttatgcgtt aaattggttt acagaccact
     1801 atcacttacc actctttatt gttgaaaatg gttttggagc tatagatcaa gttgcagcag
     1861 atggtatggt acatgatgat tatagaattg aatatctagg tgcccatatt cgtgaaatga
     1921 aaaaggctgt agttgaagat ggtgttgatt taatgggtta tactccatgg ggatgtattg
     1981 atttggtttc agctggtacc ggtgaaatgc ggaaacgtta tggttttatt tatgtagata
     2041 aagatgataa tgggaaggga agttataatc gttccccgaa aaaatctttt ggctggtata
     2101 aggaagttat ttcatctaac ggtgaatcag tagaatagta taaacaaact gagattattc
     2161 tcagtttgtt tagcatattg aggtgacata tgattggaag tattgcagca attttaacaa
     2221 catttgcatt tttaccacaa gtttttcgtg tagttaagac aaaggacaca ggatctattg
     2281 ctctaggtat gtatgttatg caagttattg gtattgcatt gtggcttgct catggtattc
     2341 gtataggaga cttgcctttg attttagcaa atagtgtttc atttctactc tcaggaataa
     2401 ttttatttta taaattgaag tataaataat ttttttccat atcatttagg aaaatgaggg
     2461 aattgtcatt ggaaacgctt tattttataa taaaaataga taacaaataa gccaacttag
     2521 cacagctttg attggattta agaaaaggag aaaatattat ggcaaaagct ttaattattt
     2581 gtgcagcagg aatgtcttca tcacttatgg cacagaaaac aacagagttt ctaaaaggaa
     2641 aagggaaaga tattgtagtt gatgctatta gtgctactga aggagggaaa gctatcgcag
     2701 cagcagcttt tgatttgtat cttgtcagcc ctcaaacaaa aatgtacttt aagcaatttg
     2761 aagaggctgg ttctaaagca ggaaaaccag ttgtacaaat acctcctcaa gcctatattc
     2821 ctattccaat gggaattgaa aaaatggcta atttgattct tgagaatatt tgatgaacac
     2881 atgaaatgtc aataaatatt taagttaaga taaattgttt tgagtttgat ataaattgat
     2941 ttaagtgtat aatatgcttc aatatatgaa aacatacgtt ttaggaggga atgaatgtgt
     3001 taaacattaa agagaaagat atccttcaat ttttaataaa aaataaggaa cgttttgtta
     3061 caagcaaaga actggcagaa tatttatcct gttcagatag aactgtccgt aatgtactga
     3121 aattaattga gaagacaatg attattcaag gagtccggtt gatttcaaaa caaggtcaag
     3181 ggtatcaaat attttttgag aatcaaggcg cttaccagga gtttagacaa acttatgaac
     3241 tggaagaaga ctatacgaaa actgcggttt caaaaggtga tgatcgttta gtatttatct
     3301 taaataaatt attatttgag caagttccag ttctttttga tgatttagct gatgaacttt
     3361 acgttagtcg ttcaacatta tctcatgatt tcagaaagat acgagtgatg ttatcagagt
     3421 ataatttgtc cattgagagt agggcgaata aaggagttta tgtctcaggc gaggaacgtg
     3481 ataaacgacg ttttatcata aattatttcc tagagaatca attttttaaa acaatacatt
     3541 gctatgtaaa atttaacttt tttgctcaaa ctgttccatt agaagaattt gctagaattg
     3601 ttttggatga atgccaagag gccaacctaa aactatctga ttttgtacta cagaatttag
     3661 tagttcacat agcattgtct gtgattcgtt taaaatccgg atttgaaata aaaaatatag
     3721 actgtcagat gactgatgat gcaatagaga gaaaggttgc tcaaagaatt ctttctaaag
     3781 taagagaagt aacaaatcag gaatttccag ttcaggaaat agactacatt actttgcatt
     3841 tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa tatttctgaa gaagttttaa
     3901 aaaaatcttt atttaaaaca tttcagaatt taggattaga tgatatgtat aacttttctt
     3961 cagatttcca actaattgaa ggattgataa ctcatctaat gacactacaa gtacgtttag
     4021 aaagccggat taccttaaat aaccctttgg tagatgaaat taaacagaat tatagtgata
     4081 tattctttat gactagagaa attcttgcaa atatggacaa gttcttggag tggacaatat
     4141 cagatgatga agtagcatat gtaagtcttc actttttagc tgctatggaa cgtagcaaag
     4201 agagtactaa gtttaatatt cttgctattt gtgcaacagg atttggtgca gcccaaatgt
     4261 taagaaatcg tttggaaacg gagtttggga agcgagtaga agttgttgat gtaataggct
     4321 attatgaatt gaatcaagaa aaacttaaag gaatagattt tatagtgtca gctgttgatt
     4381 tatcaaatct atattttcaa attccagttt ttaaagttag tgtgtttctt aagagtgatg
     4441 agatggaaat gattagaaaa gctatggatc agatgcaagt ttctagttat gtacaatcat
     4501 caaagattaa taaatttgaa aacaacagct ttagacagta ttttagtaaa gaaaattttt
     4561 taatatgtac tgaatcagac aaggtaaatt tacttgaaaa gatggttgag agtttatctg
     4621 ttggtgaatc aaatgagttt gaacaatctt tactttatgg aattaaacag cgcgaagaat
     4681 taagttcagt tgttttttct gaaaaaattg cagttccgca tcctattcag ccctttggta
     4741 cagagggaaa ggtttcggtt gcaatttgta aagattcgtt actctgggat aatcaaagtt
     4801 catatgtcca gctagtattt cttctatctc catcaatata tgggaacgaa ggtttggcaa
     4861 ctgtgactaa aaagatagtc tctctgacag agaatgatga attgcaaaat cagctaatat
     4921 cttgcaataa ctttgaagat tttattaaca tatttgagaa gataaaatag gaggttcata
     4981 tgaatcaaga ggaactgcag gttgcagcat ttgaaattat tctgcattcg ggaaatgcaa
     5041 ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg tagttttgat gatgcagaaa
     5101 gtaaattaaa tcaatcaaat gagataattc ttgaagcgca tcatgcacaa accaaactct
     5161 tgcaagaata cgcaagtgga gtggaaatta aaattgaaat tatcatggta catgctcaag
     5221 accatttaat gaccactatg acattattag aagtagcaaa ggaaatgtta gctctttata
     5281 agaaagttaa ctaaatatgt gttgttatat aaggaggaaa tgatatggat aaaaaagaac
     5341 gacaaaaaat tgaacaacaa cgtcgagaga tggctctaac taatactttt tttaatcgat
     5401 atcttcttct acgttattca atagcactct tcttttttgg gaatatttat tggcttttga
     5461 atcagtttat tagtccctcg cctattatta ttttccccat tatgctcata gtattttcta
     5521 ttttagcaac tattgaacaa tttaaacttt atggaaatag gaaagaaaag ttgggaataa
     5581 cactaatgtt tgttagaata caaatgctta tttcaatagg attacttgtt ttaacttgga
     5641 caagttggtt tgagaatctt tttccgattt ttgaaaataa ccaagtagca cgtttatttg
     5701 tttttgtagt tcttctatta ggtttagttc tgagtttgtt agacattaga agaattaaaa
     5761 aaatttataa acgaacagat aaggcttatc aacaatttgt ccaattggaa aagaactcac
     5821 ttagtttata atcctgaact agtataattt gtatttgaaa ctagtcttta aaaagtaaaa
     5881 attattatgt tttattaagg aggtctattt atggatcaac aaaacgggtt gtttggtttt
     5941 cttgaaaacc atgttatggg accaatgggc aaacttgctc agtttaaagt agtgcgtgct
     6001 atcacggctg caggtatggc tgctgtacca tttactattg taggatcaat gtttttggta
     6061 ttcagtattt tgccacaagc tttctcattt tggccaattg tggcagatat tttctctgct
     6121 tcatttgata aattcacatc actttacatg gttgcaaact atgcgactat gggttctcta
     6181 tctctttatt tcgttctatc acttgcatat gaattgacaa aaatttatgc agaggaggaa
     6241 gaactcaata tgaattctct taatggtgcc ttgctcgcct tgatggcttt tgtcatgaca
     6301 gtaccgcaaa tcatttttga tggtggaatg atgaagactg tgacaagtct aaaagaaggt
     6361 gcagtaattg cagatggatg ggcaatggga aatggagtcg cacgttttgg tacaacagga
     6421 atttttaccg caatcattat ggcaattgtg actgttctta tttatcgtat gtgtgttaaa
     6481 cataattggg ttattaaaat gcctgaagct gttccagaag gagtttctcg tggatttacc
     6541 gctttggttc cgggatttgt tgttgcattt gttgttatct ttatcaacgg tcttcttgta
     6601 gcaatgggaa cagatatttt taaagtcatt gcaattccat ttggttttgt atccaatctg
     6661 actaattcgt ggattggttt aatgattatt tatctattga ctcaactact ttggattgta
     6721 ggtatccacg gtgcgaacat tgtttttgca tttgttagtc caattgctct tgctaacatg
     6781 gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg aattttctaa tatgtttgta
     6841 attgcaggtg gttctggtgc aactttagga ctatgtttat atattgcttt tgcctctaaa
     6901 tctgaacagc ttaaagcaat aggacgagca tctgtagttc cagccttatt taatattaat
     6961 gaaccattaa tttttggatt acctattatc tataatccag ccttggctat accatttatt
     7021 ttagcaccaa tggttactgc tactatttat tacgtagcga attctctaaa ctttattaag
     7081 ccaattatcg cacaggttcc atggccaact ccagtaggga ttggagcttt cttagggaca
     7141 gcagatcttc gagctgtatt agttgctcta gtatgtgcat ttgcagcatt cctagtctat
     7201 cttccattca tccgtgtata tgatcaaaaa ttggtgaaag aagagcaagg tatctaataa
     7261 gtaaaaaagt atactcgatg atagaatcca tatagtttaa ataatgagcg ttaacattag
     7321 cagtgaagag gtctttttaa gatattcttc tctgcttttt catatttttt cgctatgtag
     7381 agtatgaagc aaaatagaaa gtagttcgaa tagttgataa acagggaatt gctgttattt
     7441 aaaaaaaaca ataaagtaaa gtatgttatc gtagaatacg atacaatagt aaaaaagcaa
     7501 aaagaatgcg ttttatattt gggtttgagg cttataaaat aggataagcg tactgaaaac
     7561 ttagatatga caaacaaaat aaaattttta aaagctacag agaaacatgg tataatgtat
     7621 ctaaaggagg tagcatatgt ccttagatat agataaagaa aagatgacaa tcatgggaat
     7681 agcttttgaa aaccgatccg tttttaagag tgtttggtat gctttaagta caaatatgat
     7741 tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag ctctttctct
     7801 ggggatgact taatgaagcg caactgttat gagtcttatg actatgttga tccggataat
     7861 ttatataccg atccgggttc ttcagttcta agaaataagc aggaaggaaa aaagcacgcg
     7921 agcttgaata tcgtatgatt gctagtaaga gtttgaaatt atttatcaat cctatcttag
     7981 ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt tgaaaagtga
     8041 taactcttta ataaactctt ggtttgttaa aagatatttt gtccactaca tttttttcaa
     8101 ttgactatta tttgtcatag atataacaga tagaacattg cattcagaat aatgaaaaac
     8161 gcatcaaaaa tggtgcgttc tgtttttatg ctaccataaa aggaggaaaa caaattgaaa
     8221 atttttaagg gagagtttta tcgaatctct gtattaacag acaagctagt aaggttagaa
     8281 tactctcgaa ctggaaattt tgaggataga acgacacaac ttatctataa tagagatttt
     8341 ggccaagttt cgttagatta tatcgagaca tcaaatgtac tagatattat gacggactat
     8401 tttcatctgc actttaataa aggagaattt aacgccgaaa atttatttat agaattaaaa
     8461 ggaaattttg ccgtatatgg tagtcgctgg tattttggtg aatctattga aacgttaaaa
     8521 ggaacagctc ggactctgga taaggcagat ggagcaatct cgttagaaga tggaattatt
     8581 agccgaaatg gtatagcctt attggatgat tctcaaggat ttatttggga tgaacaatct
     8641 ggttatattg agagagaaaa tcaaattgac ctgtatttct ttgcctatgg gcatgattat
     8701 agaggagcaa tcagagactt ttaccatttg actggttcaa cacccttgtt gccaagatat
     8761 gctttaggca attggtggag tagatattgg ccttatacgt cggatgaata cttggattta
     8821 atagacagat ttgaaacaga gaaaattcca ttatctatcg gtgtgttaga tatggattgg
     8881 catataactg acattccagc tcgttttgga agtggctgga caggatatag ttggaataga
     8941 aacttaatac caaatccaga acagttattg caacaacttc atgatagaaa gttaaaactc
     9001 tccttaaatg tccatcctgc tgatgggata cgggcttatg aagaagctta tcctcaaatc
     9061 gcaaaacggt tggggttaaa tgtagaacta gaagaacctg ctatttttga tttttttaat
     9121 ccctctttta gggaagccta ctttaaagat gttcattatg agctagaaaa gcagggagta
     9181 gatttttggt ggattgactg gcaacaaggg acacaaggta tgctagatcc actttggctt
     9241 ttaaaccatt atcactatca ggatagttgt aaaaatgcag aaggtggttt gattttatca
     9301 agatatgcag gtcctggtag tcaccgctac cctgttggtt tttcagggga cactattatt
     9361 agttggaatt ccttaagatt tcaaccctat tttacagcga cagcatctaa tatcggttat
     9421 agttggtgga gtcatgatat cggtggacat atgttggggg attatgacga agagctacaa
     9481 actagatggc tacagtttgg tgtttttagt ccgattactc gattacatag ttctagaagt
     9541 ccttttaata gtaaagaacc ttggttcttt tcagaaacaa catctaagat tatgaagaaa
     9601 taccttcgtt tgagacatca gatgattccc tatctatata ccatgaatgt aaagacacat
     9661 gaggaaggtg ccccattaat cagtccaatc tattatttct atccagagaa tgatgagagc
     9721 tataatgttc caaaccaata cttttttgga acagaactga tggtggctcc cattgtagaa
     9781 aagatggatt tgacattcca atctgcaaaa gtagatgtat ggttccctga agatgaatgg
     9841 tatgacttct tttcagagaa aaaatacaca ggtggtgtga agttaagtgt ttatagggac
     9901 atctcgacta cgcctgtgtt tgcaaaaagt ggtgcaatca ttcccttggt tggttctgag
     9961 ataggtatgg gtgttgattt acctgaggtt gtagattggt atgtattccc agggaaacaa
    10021 cattcttttg aaatgcttga agatcaaaat ggtcaaagat ataaaacaag attatcaatc
    10081 gattgggaaa tgggaatggt agagttagca ttacaaggag attctagtat cgttccaagc
    10141 aatagaaaac atagaattca ttttaaagga acgaatgtgt ctataattga attgccaaat
    10201 aagaatgata cagctaaatt tgaatggaaa gataataaaa ggacatcttt aaatgacgaa
    10261 gtttttagac tactaaagac agcttctctt ccatatgaat taaaagatag attgttaaat
    10321 caattcatca atgcgaaaaa ctctcatgac ttaatgaata tcttgcatca tcaggataag
    10381 gaattgagag ggcgtttgtt ggaaatgata tttactagcc aaaactaatt gaaataatta
    10441 gaaagtcatt tgtttagtgt atatgaagat tctgtatggt attcgttatc actggtcaca
    10501 ttgaaaatgt gaaataagca cctacaacat agactttaca acacttcatg ttttatatca
    10561 tggggtgttt ttctatttaa gtcaaagccc atcaaaaaat ctcactattc atcaggttaa
    10621 aggaaaccta atcatagtga gattgtgaat tatagtagag tttgtatcgc ctcttcaatt
    10681 tgttttgggt ttgtttttga agaaaagcgt tcaaagactt gcccatcacg accaatgaga
    10741 aacttagcga aattccattc gattcgtttt cctagtgggc cagatttatg gtcttttaac
    10801 cagacataga gagggtctgc ttccttaccg ttgaccttaa tcttggcaaa acgtgggaag
    10861 gtggtttgaa aatgtaggct acagaaggcg ttgatttcct ctgcgctgcc gggtgcttgt
    10921 cccataaact gattgcaagg gaaatccaat atttcaaagc cctgatcttg atagcgttca
    10981 tagagttctt gaagtccctg gtactggggc gttaaaccac atccagtagc agtgttgaca
    11041 atcaagagaa ctttaccacg atagctatcc aagggagttg cttggttgtt ttggttcaaa
    11101 acggaaaaat cataaagtga agtcatgagg gcctcttttc tttttctaca ttgtaacagt
    11161 ttttactttt ttcgtcgagt cggatggaag atattgttga agaataagcc ttcaatatga
    11221 tagaaaccgt ttacaaataa ctttaaaaat ggtatgattt aattaaaccg gtttactttg
    11281 ttgctataaa tctctaattt gagatttagt tcctattgat tttacaatat gtttattgga
    11341 gtgtatacat gcaaacaaaa acaaagaagc tcattgtgag tttgtcttca cttgttttat
    11401 caggattttt attaaaccat tatatgacag ttggagcgga agaaacgact acgaatacca
    11461 ttcagcaaag ccagaaggaa gttcagtatc agcaaaggga tacaaaaaat ttagttgaaa
    11521 atggtgattt tggtcagacg gaggacggaa gcagtccgtg gacaggaagc aaagctcagg
    11581 ggtggtcaac ttgggtagac cagaagaata gttctgcaga tgcctcaact cgagtcattg
    11641 aggctaagga tggggctatc actatctcaa gccatgagaa attaagggca gcgcttcacc
    11701 gtatggttcc tattgaagct aagaaaaagt ataaactgcg tttcaagatt aaaacagatc
    11761 ataaagtcgg gattgccaaa gttcgtatca ttgaggaaag tggtaaggac aagcgattgt
    11821 ggaattctgc aacgacgtca ggaacaaagg actggcagac cattgaagca gactatagcc
    11881 cgactttaga tgttgataaa atcaagctgg agttattcta tgaaacagga actgggactg
    11941 tttcctttaa ggatattgag ctggtagagg tagcagacca gccttctgag gattctcaaa
    12001 cagataaaca gcttgaggaa aagattgatt taccaattgg aaaaaaacat gttttttctc
    12061 ttgcggacta tacttataag gtagaaaatc ctgacattgc ttcagtcaaa aatggaattt
    12121 tagaacctct taaggaaggg acaaccaatg tcattgtcag taaagatggc aaggaagtga
    12181 aaaagattcc tttgaagatt ctagcctctg ttaaggatgc atacacagac cgtttggatg
    12241 actggaatgg catcatcgct gggaatcaat actatgattc taaaaatgaa cagatggcca
    12301 aattaaacca ggaattggaa ggaaaggtag ctgatagcct atctagtatt tcaagtcagg
    12361 cggaccgcac ctatttgtgg gaaaaatttt caaattataa aatgtctgca aatctgactg
    12421 ccacttatcg gaaattggag gagatggcca agcaagtgac caatccttct tctcgttatt
    12481 atcaagatga aactgtcgtt cgaacagtca gggattccat ggaatggatg cataaacatg
    12541 tctacaatag tgaaaagagc attgttggga actggtggga ttatgaaatc ggtacacctc
    12601 gtgccatcaa caataccttg tctctgatga aagaatactt ctctgatgag gaaattaaaa
    12661 aatatacaga tgtgattgaa aaatttgtac cagatcccga acatttccga aagacgactg
    12721 ataacccatt caaggctcta ggtggaaact tagttgatat gggaagggta aaagtaatag
    12781 ctggtttact gcgtaaggat gatcaagaaa tttcttctac cattcgctcg attgagcaag
    12841 tgttcaagtt ggtagaccaa ggtgaaggtt tttatcaaga tggatcctat atcgaccaca
    12901 ccaatgttgc ctatacgggt gcttatggga atgttttgat tgatggcctg tctcaactgt
    12961 tgccagtcat tcaaaagacc aagaatccaa tcgataaaga taaaatgcaa accatgtacc
    13021 actggattga taaatcgttt gctcctttgc tggtgaatgg agagctgatg gatatgagtc
    13081 gtggacgctc gatcagtcgt gcaaatagcg aggggcacgt ggccgcagta gaagtactaa
    13141 gagggattca ccgaatagcg gatatgtctg aaggagaaac caaacaacgt ttgcagagtc
    13201 ttgtgaagac cattgttcaa tcggatagtt attatgatgt ctttaagaat ttgaagactt
    13261 ataaggatat cagtttgatg caatccttgt taagtgatgc aggagtcgca agtgttccaa
    13321 gaacaagtta cctatctgcc tttaacaaga tggataaaac agccatgtac aatgcagaga
    13381 aagggtttgg atttggcttg tcactctttt ccagccgtac cttgaattac gaacacatga
    13441 acaaggaaaa taaaagtggt tggtatacga gtgatgggat gttctatctt tacaatggcg
    13501 atttgagtca ctatagcgat ggctactggc caacagttaa tccatataag atgcctggta
    13561 caacagagac ggatgctaag agagcggata gcgatacagg taaagtttta ccgtctgctt
    13621 tcgttggaac gagcaaacta gatgatgcca atgcgacagc aaccatggat ttcaccaact
    13681 ggaatcaaac attgactgct cataagagct ggtttatgct aaaggataag attgcctttt
    13741 taggaagcaa tatccaaaac acttcaacag atactgctgc aactacaatt gaccagagaa
    13801 aactggaatc aagtaatcca tataaagtct atgtcaatga taaagaagcc tcccttacag
    13861 aacaagaaaa ggattatcct gaaacccaaa gtgtcttttt agaatcgtcc gattcgaaaa
    13921 agaatattgg ttactttttc tttaagaaga gttcaatcag tatgagtaag gctttgcaaa
    13981 agggagcctg gaaggatatc aatgaaggac agtcagacaa ggaagttgaa aatgaatttc
    14041 ttactattag tcaggctcat aagcaaaatg gagattctta tggctatatg ctcattccta
    14101 acgtggatcg tgccaccttc aatcaaatga taaaagagtt agaaagtagc ctcatcgaaa
    14161 ataacgaaac ccttcagtct gtttatgatg ctaaacaagg agtttggggc attgtgaaat
    14221 atgatgattc tgtctctact atttccaacc aattccaagt tttgaaacgt ggagtctata
    14281 ccattcgaaa agaaggggat gaatataaga ttgcctacta taatcctgaa acccaggaat
    14341 cagctccaga tcaggaagtc tttaaaaagc tagagcaagc agctcagcca caagtacaga
    14401 attcaaaaga aaaggaaaaa tctgaagaag aaaagaacca ttcggatcaa aagaatctcc
    14461 ctcagacagg agaaggtcag tcaatcttgg caagtctagg gttcttgcta cttggggcgt
    14521 tttatttatt ccgtagagga aagaacaact aatttgttca tcatctagat gaattacatg
    14581 aaactgtgga aaatagaaaa aatccgaaga aggccaaata tcttcggatt tttcttttaa
    14641 aaagggataa gttgatactt atcctttttt acttcattat gtgactatag cgttttgaaa
    14701 ctagaatagg acgtcataac tgctaaaaga tttctataaa ttcatttgat tttcctaatc
    14761 aatttgttcg tatcctattt cactccacta tattagtccg tctcgctccg tgaggtgcga
    14821 gacaaaacaa ccacccgcta tgcgggtgcg cgtcgaaggc tataccaaaa aactccaaac
    14881 gcgatacaat aaaggtgttc aatccaattg taaagcgaaa ggagaaaaaa tatggcacaa
    14941 aagactcata gtttatcata cacaaagtgg atgtgttcta tcatattgtg ttcaccccta
    15001 agtatagacg aaaagtcatc tataatcaat atagaagtag tttaggcgaa atatttcatc
    15061 gcttgtgtgg ttataaaggt gttgaaatga tcgagggtca cttaatgcca gaccatgtac
    15121 acatgttagt cagtattcca ctaaggctaa gtgtttcgag tttcatgggg tatttaaaag
    15181 gcaaaagtgc actcatgatg tttgacaaac acgccaatct caagtacaag tttgggaatc
    15241 ggcatttctg ggcggaaggt tattatgtaa gtacagtagg gcttaataaa gccacactta
    15301 agaaatatag tcaagattaa agaaattatc gagtggatga tttcttcacg agtatgaaaa
    15361 tttgagaacg agtaaagtat gatatatagt aaaatgaaat aagaacagga caaaatcgat
    15421 caggacagtc aaatcgattt ttaacaatgt tttagaagta gaggtgtact attccagttt
    15481 caatctacta tagcactaga taaattgagt gtaaaagaat atgaggatcc ctttagggat
    15541 agtggtaagt aataccaaag tctcttaaag aggcaagtga cgagtcaaga gcaataaggc
    15601 ttgaacaacg tgaaagccag cgtctttagg cgctggctgg taatttgggc ttatagctct
    15661 gggataaacc acccgtttga cgggtggtta tgattttatc tgagtgtaac atactgttgg
    15721 gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga gtttattgag ttcgccacca
    15781 attccaacgg cgtctgcacc agcagcgaac cattgaggga tgttgtttag accgactcct
    15841 ccggttacca ttacggaaac ttgtgggatc ggtgccttga ctgcagagat atatgctgga
    15901 ctgagagcac tacctgggaa gagtttgatg atttcactac cggcttcaag tgcagtcgtg
    15961 atctctgtga gggtaataca gcctggaatg tacggtgtgc tgtagagatt gcacattttc
    16021 gcagtttcag catggaaaga tggagaaaca acgtaatttg ctccggctag aatggcatct
    16081 ctagcagtta cggcatcaag cacagtacct gcaccgatac aaacactctg atcgtcctga
    16141 tacaagtcta caagttcctt gatgatttgt cctgcatact gattggtata ggcgatttca
    16201 atagctttga taccgccctt gatacaagca atcgaggctt gcagtccttc ttcctttgta
    16261 tttcctcgaa tgacagcgac aattttctgt ttttttagtt caataatcgt atctgatttg
    16321 gtcatgtaat tctcctaacg aatgatatct tgtgcatttg ccagtaaatt ttcaatacta
    16381 gttgcggaag tggagagatg gtctcctgga agagtgcatt tgagagttgc gctcgcaact
    16441 gcaaagtcaa tggtagtttt tagggaggaa tgatggagta gttggtaaag ggcaccagat
    16501 ataaaggcat ccccgctacc aattcgttga tagactgcag tttttagttg gacagactct
    16561 tcaaatcgtt cttccagagc ataggcttga tagacatttt tgtcttgctc atcactagag
    16621 cggagggtat ggaaaatggc cttgaaacca taggcttctt ttaaaagtcg catgcgattt
    16681 tccacctctt ctaggctagc actgtctctt ggaaacatct ctagattttg gtcatcaatc
    16741 atgagaggat caataccgaa gcaatagtca gtaaaacgtg caaacttaga aaattcatac
    16801 ttggcttcta ggactgaaat catctttgtt ctcagattga gatccattga aacgacaatt
    16861 cctcggcgct tggcttcttc caagagtagg agaaggatcg cacggacctc ttgaccgata
    16921 gctacggtga ttccactaaa atgaaaatgg ctaatcccct gaaagagaga atccatatct
    16981 agcatgtttg gccgaatctg gctgatactc gtatgcttac gatcgtagaa aacttcactt
    17041 tgacgacaac caaagccgtt ctccaaatag tagaggccga ttcgatcgcc aagccgacag
    17101 attgaactgg tatcgatttg gtgctgtttc aagaatgtga gaaaacgatc tccaatctcg
    17161 ttggcaggga gtgcggtaaa gactttcgtt gagataccca gggcttgcaa attacaagcg
    17221 atgttaattt ctgatccgcc aaaataagtc gaactggcaa catgatcgcc gatactggtg
    17281 gcatctaatg gtgagattcg aattaatggt tcgccaaaca gtaatatttt cgtcatccat
    17341 tagttccttt ctggtttaga atagctttac ttggctaata cttctttcaa ataagcagcg
    17401 acttcatcat cttggcagtt ttcaaagaag tattcttgga aatatttgcc agagatggtg
    17461 tctttgagga agtcttggtc gattgtttta aggatggtca tcaaatcatt gtgggtgatt
    17521 tgtttcacct cgtttaagat acgagcgttg cgttgttcag ggattacacg ttctcttggg
    17581 tagccaccgc ccatttcttc agcaaataag cgttcaaaca tcaatttgag ggtcagttct
    17641 gccccccagc caaatccttt ggcataaggg atagacaagg cgttaccacc attgatttga
    17701 gaataaaggt aagcgtcagt tgggtccact gctagaccac agacaacacc agggaagctg
    17761 tttaaagcaa gcatagcccc tacacccgta ccacagccgg taacaacaaa gtcaactgcc
    17821 tttgtattta aaaggatggc agccattagt ccgttctgca cataagttaa ttgactttct
    17881 ccttcttctc cacgcatacc atagttaaat aattggtagc cttttttatc tgtcgcttct
    17941 tttagactat cgtaaataat gtgattcttg ctagcttgac tattttcatt gattaatgcg
    18001 attttcataa gatcttcttt ctatttttac tcaggttgtt ttccgatgta ggctaagata
    18061 ccgccatcta catataggat gtggccattg acaaaattgc tggcatcact agcgagaaag
    18121 acagcagggc ccatcaaatc ttcaggattt ccccaacgtg cagcaggtgt ttttgcaatg
    18181 atgaactggt caaatgggtg gcgagaacca tcttcttgca actcacgaag aggtgctgtt
    18241 tgaggagtgg caatataacc cggtccaatt ccgttacatt ggatattggc tccaccgtat
    18301 tcagacgcaa tgttgcgggt caacattttc aagccccctt tagcagcagc ataagcgcta
    18361 actgtttcac gtcccagttc gctcatcatc gaacaaatat tgataatctt tccatgccct
    18421 ttctttatca tagaaggaat aactgccttt gaaacgataa atggtgcgtt taagtcaata
    18481 tcgatgacct tacggaaatc agcggcgctc atttcgcaca ttggaactcg gcggataata
    18541 ccagcgttat taacgaggat gtcaatgaca ccaacctctt gttcgatttg cttgaccatg
    18601 gcttggatac cgtcctcgtc tgtcacgtca cagacatatc catgggcttc gatgccaact
    18661 tcacgataag cttcaatccc tttattgacc agatcttgat tgatatcgtt aaagacaata
    18721 gtagcgccgg cttcagcgta ggatttggca atagcaaatc caattccata agaagcgccg
    18781 gtgatgagag caatttttcc ttttaaagaa aactgctcaa ttgagaatga tgtatttgtc
    18841 atttgatact tcctttcaaa tttgttaaga cttctctata accaaattat attctagtaa
    18901 accggttttg tcaataaata aatattttta tttataaaaa gatttatttt ccttaaaaat
    18961 ggaatatttt gaaatttctg tctattaaaa tgattaaaaa gataatgaaa gcgctaatat
    19021 ttttttaaaa aaactattga caagataaaa ataaaggatt acaatgggga atataaagta
    19081 aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat tgtacttgta gggcatggac
    19141 attttgctac agggatttat agttctttac aattgattgc aggcaatcaa gaaaatgtgg
    19201 aggcaattga ctttgtggaa ggaatgtcag cagatgaact caagcaaaaa atcttacttg
    19261 caatttcaaa tgaagaagaa gttttaatcc taagtgatct cttgggagga tcgccattca
    19321 aggtttcttc taccataatg ggagaaaatc cagccaaaac aatgaatgtt ctctcgggtt
    19381 tgaacttagc catgttaatg gaagcagtct ttgctagaat ggctcatagc tttgatgagg
    19441 ttgttaataa atcagtagtg gcggcccggg gcggagtcgt aaatggtaaa gaattgtttt
    19501 caacggatgc agaggaagag gaagaagatt tcgaatcggg tatttaaagg gtaaaagaat
    19561 gataaaaaag gttacgattg aaaaaataaa atcgcctgag cgcttcttag aagtaccact
    19621 tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt attcggcagt tagaactcaa
    19681 ccttgactat ttcaaggaag atttcccgac gccagctacc tttgataatg tctatccaat
    19741 catggataac acggaatgga ccaatggttt ctggacagga gaactgtggt tggcttatga
    19801 atacagtcaa caggatgcat ttaaaaacat cgctcataaa aatgttcttt ctttcctgga
    19861 tcgtgtcaat aagagagtag aattggatca ccatgatctc ggcttcttgt acacaccgtc
    19921 ttgtatggct gaatataaga taaatggaga tggagaggct agagaagcaa ccttgaaagc
    19981 tgcagataag ttgattgaac gctatcaaga aaaaggtggt tttattcaag cttggggaga
    20041 cttgggcaag aaagagcatt accgtttgat tatcgactgc ttgctcaata tccaactctt
    20101 attctttgct tatcaagaaa caggcgatca aaaatactac gatattgcag aaagtcattt
    20161 ctatgcttca gctaataatg taatccgtga tgacgcttcg tccttccaca ccttctattt
    20221 tgatcctgag acaggtcaac cctttaaagg tgtaacgaga caagggtata gtgatgattc
    20281 atgctgggca cgtggtcaat catggggagt ctatggtatt cctttgactt atcgtcactt
    20341 aaaagacgag tcctgctttg acttgtttaa gggtgtgacc aattatttct tgaatcgtct
    20401 gccaaaagat catgtgtcct attgggattt gatttttaat gatggtagtg ctcaatcacg
    20461 agattcttca gcaacagcta tcgccgtctg tgggattcat gaaatgctaa aacatctccc
    20521 agaggtggat gctgacaaag atatttataa acatgctatg catgccatgc ttcgttcctt
    20581 gatcgaacat tatgcaaatg atcaatttac ccctggtggg acaagtctcc tccacggtgt
    20641 gtactcatgg cattcaggta aaggagtgga tgaaggcaat atctggggtg actactatta
    20701 cctagaagcc cttatccgtt tctacaaaga ctggaaccta tattggtagg aggagaaata
    20761 tgacaatgcc aaatattatt atgacccgta tcgatgaacg gttgattcat gggcaaggac
    20821 aactttgggt aaaataccta ggttgtaata cggtcattgt tgccaatgac gaagtaagca
    20881 cagacaagat gcagcaaact ctgatgaaaa cagttgtgcc agactcagtt gccatgcgtt
    20941 tcttcccttt gcaaaaggtg attgatatca ttcacaaggc taatcctgct caaacgatct
    21001 ttatcgttgt aaaggatgtg aaggacgctt taaccttggt agaaggtggt gtccctatca
    21061 aagaaatcaa tattgggaac attcacaatg ctactggtaa agagcaagtg acacgctcca
    21121 tcttcctggg tgaagaggac aaggcggccc tcaaggaatt gagccaaact catcaagtaa
    21181 catttaatac gaaaacaact ccaacaggaa atgatggagc tgttcaagtc aacattatgg
    21241 actatattta aaagaggaga tcgttatgtc gattaatgta tttcaagcga ttttaattgg
    21301 attatggaca gctttctgtt ttagtggaat gctgttagga atttacacca atagatgtat
    21361 tgttctgtca tttggtgtcg gaattattct aggtgatttg cctactgctc ttgcaatggg
    21421 agctattggt gaattggctt atatgggatt cggtgttggt gctggaggta ctgttccacc
    21481 aaacccaatc ggacctggta tctttggtac cttgatggct atcactagtg ctggtaaagt
    21541 cagtccagaa gcggctcttg ccctctctac tccgattgct gtggcgattc aattcttaca
    21601 aactttcgcc tacactgtac gtgctggtgc gcctgaaacg gcgatgaagc acttgaaaaa
    21661 ccataatttg aagaaattca agttcactct aaatgcaaca atttggttgt ttgcctttat
    21721 tggatttacc ttgggttgct tgggtgccct ttcaatggat accttgttga aactcgtaga
    21781 ctacattcca ccagtattgc ttacaggttt gacagttgct ggtaaaatgc tcccagctat
    21841 cggttttgcg atgatcttgt cagtgatggc taagaaagag ttgattccct ttgtcttgtt
    21901 gggatatgtt tgtgcagctt atctaaacat cccaacaatt ggtattgcaa ttgtaggtac
    21961 tatctttgct ttgattgaat tttataacaa gccaaaaaca gcggatcatg tggtagagga
    22021 ggaagcacac gatgactgga tctaacaaat taacaaaacg tgattatctt aaaacgtctt
    22081 tgcgggcatt cttttgtcaa aatggattta actatagtaa ctatcaaggg ttgggatatg
    22141 ccaatgtgat gtatcctgct ttgaaaaaac actatggaga ggatcaggaa gttttctacc
    22201 aagccttgga agaaaactgt gaattctata ataccaaccc acacttcctg ccttttatta
    22261 ccagcttgca tcttgtaatg ttggaaaatg gccgaccaac aaaagaaaca cgtagcatca
    22321 agatggcctt gatgggacca ttggcaggta ttggggattc tctttctcaa ttctgtttag
    22381 ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga aggcttggtt gtcggtccaa
    22441 tcttgttctt ccttgcgatg aatacgattt taacagcgat taaattgtca actggtctgt
    22501 atggatacaa actaggaaca actgtgattg ataaactaag cgaacagatg gcaacgattt
    22561 ctcgtattgc caatattatc ggtgtaaccg taattgctgg tttggcagcg acatctgtta
    22621 agattatggt gccgattacc tttgctgcag gggaagttaa agcagacgct aaacaaagta
    22681 tcgtaagtat tcagggaatg cttgataagg ttgctccagc tcttctacca gccctattta
    22741 cacttttagt ttactacttg atcaaagaaa agaaatggac aacatataaa ctcgttattt
    22801 taacagttat catcggaatt atcggaagct ggcttaagat tatagcttaa tggatacaac
    22861 attgttttat ggaatagtga ttgtcttggc agtgagtccc cttttactgt caagctttca
    22921 ttctattcgt cagcaaaagt tgcttcgcaa acagatggag caacgacaag agtatttagc
    22981 ttctttaaca tctggtgatg aagtgttgtt attgtctgga attcatggaa aaatcatttc
    23041 tatcaaagat gacttggtct ccttgcagat tgcaaaaggt gtggtcatct atgtagaaaa
    23101 ggaaagtgta atgggaaaga caaaagaact gctttttaag tagttctttt tctggtaata
    23161 gataatgaaa gaagaaagaa gacaattttt tgaaagaatc gatggaaacc aatgtcgtga
    23221 ttatatcttg tcccactgtt caaaagacta tgagaaagtc aagagttccc ttgaacgctt
    23281 gatggacaat cgttttatgt ttgatagtcc ttgggatatg gagccttgtt caaaaatcca
    23341 tcaaatccag ccgatggtat gggatcaagt atttgaagat gatccagaat gggcttatat
    23401 gctcaatcga caagaatatc tcttgcagtt tatgataggg tatctggtag aaggagataa
    23461 ggactatatt caaaagtgca agttctttct atttgattgg attgagcagg tgagagaatt
    23521 ttctcctcaa tccttgatga ctagaacctt ggatacgggt attcgttcct ttacttggtt
    23581 gaaactactc ttgcttctct tgaaatttga cttgctagag gagaaagaac tagagaaaat
    23641 tttggtcagt ctagaaaagc agattgactt tatgaaaagc tactatcgcg ccaagtacac
    23701 ccttagtaac tgggggattt tacaaacaat tccgatgctt gctatctatc atttcttttc
    23761 agataagatg gacctagaag aagcttacca ttttgcttca gaggagttga aacagcaaat
    23821 tgagacacag attttaggag atggaagcca gtttgaacag tcgattctct atcatgtaga
    23881 ggtttataaa gccttgctgg atttgtgtct cttgcttcca gacttgcaag atagttacca
    23941 agagttgctg gaaaagatgg cgacctatat tcaaatgatg acaggcttag atggacgaac
    24001 tttggctttt ggtgatagcg attctacaga aacgacagaa attttgagcc tgtctgctgt
    24061 ggttttgaac aaggaagacc ttcttaacgg tctggatgtt aaagttgatt tgcttagcct
    24121 cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa tttgaaagga gagcttggca
    24181 gcctaagtcc atgatctttg aagactctgg acatgtctgt attaaggatg aacatcgtta
    24241 tctatttttc aaaaatggtc cgctaggaag tgcccatagc catagtgacg agaatagttt
    24301 ttgcttacag tatcaaggcc aacctatttt catagatgct gggcgttatt cttatcggga
    24361 gatatatgaa cgttatctct taaagagtgc ttggagtcat tcgacctgca ttgtagatgg
    24421 gaaagctccg gaaagaatca caggatcctg ggaatatgaa tactatcctc actccctgtt
    24481 ttgtcaccat aaagaaaggg agggagtgca ttatattgag ggggcttatt ggtcagcaga
    24541 acctgatttg ccttatcttc acagaagaaa aatcctcatg ttggtagagg atgtctggct
    24601 cttggtggat gacatcaggt gtcaaggtca gcatgaggcg ttgactcagt ttatccttga
    24661 caaggatgtg acctatcaag atgggaaaat caatcagttg agactatgga gtgaagttga
    24721 ttttgatttg gaagatacca tcatttctcc taaatacaat gagcttgaaa gaagtagcaa
    24781 actcaccaag cgccaattct ttgagaatca gatgctggat tataccatca ttgcgcatga
    24841 gagttttgaa atcatccgtc attctgtcta ccagacagat gatcgtgaag tggaaaatgc
    24901 tctggctttt gaagtgaaaa atgacgaaac agacaagctg attctgttat taagcgagga
    24961 tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca aaaatgcgtg gaaaatgtct
    25021 agtatatgat aaaataaatg agagaatgat tcgcttgcag tgctagaaat aggcattttg
    25081 aatagtgaac atgttataat aagtattagt aggaggtgtt ttagattgga gaagaaactg
    25141 accataaaag acattgcgga aatggctcag acctcgaaaa caaccgtgtc attttaccta
    25201 aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa agattgaaaa agttattcat
    25261 gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa actccaaacg aacaaaatta
    25321 atcggtgttt tgatcggtga tattaccaac agtttctcaa accaaattgt taagggaatt
    25381 gaggatatcg ccagccagaa tggctaccag gtaatgatag gaaatagtaa ttacagccaa
    25441 gagagtgagg accggtatat tgaaagcatg cttctcttgg gagtagacgg ctttattatt
    25501 cagccgacct ctaatttccg aaaatattct cgtatcatcg atgagaaaaa gaagaaaatg
    25561 gtcttttttg atagtcagct ctatgaacac cggactagct gggttaaaac caataactat
    25621 gatgccgttt atgacatgac ccagtcctgt atcgaaaaag gttatgaaca ttttctcttg
    25681 attacagcgg atacgagtcg tttgagtact cggattgagc gggcaagtgg ttttgtggat
    25741 gctttaacag atgctaatat gcgtcacgcc agtctaacca ttgaagataa gcatacgaat
    25801 ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc ccgatgaaaa aactctggta
    25861 tttatcccta actgttgggc cctacctcta gtctttaccg ttatcaaaaa gttgaattat
    25921 aacttgccac aagttgggtt gattggtttt gacaatacgg agtggacttg cttttcttct
    25981 ccaagtgttt cgacgctggt tcagccctcc tttgaggaag gacaacaggc tacaaagatt
    26041 ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc aacaagtctt ggattgtagt
    26101 gtgaattgga aagagtcgac tttctaaaat gaaggaaaat gacttgcaat ctctgttaag
    26161 aaataaaata atcccaccta gaacaagcta ggtgggatta tttgcctatg aaatgagaaa
    26221 ttatgggagc aagctcctaa atcaactgtt tttgatctac ttctttaact acttgataaa
    26281 agttatagaa gtaggccaaa cttgaaatga tggttacgac taggaatatt gaaaatttcc
    26341 attggacagg gttggttaaa agttgtggaa aggatatgag gagaaagaag agggctgcgt
    26401 tgaggacagg tatccgtttt gattgtattt tctcaagtcc tttattgagc gcaggaagaa
    26461 agaggagtag gagtagtaaa actgtatgag aaacagctcc tgaaataagg gcaaagaaaa
    26521 ggaaaatact gataaaaaca tgaatgatca gtagtctagc tagtgatttc ataaggtacc
    26581 tcctaatcct ggtctttttt agctcttgca atacgaagtg agtcgacaat atgtatcatc
    26641 actccgaaaa agaaagctcc cagtatagtt ttaaaaatat gttttgtatt tagaagagaa
    26701 ctgataaaat ttggattttc acttgttagg gtatcaatga gtggaattat aaaaaatatc
    26761 actgttccat aaatcgaacc tgctttcaga ccaggataac gtaactgttt cttttctttt
    26821 ttcatgagtt tgctcctttt ttaaaaatct tcctcccaaa agagactgtt gaggtcagtt
    26881 tggaggctgc gggcgagatt gagacagagt tccaaggttg gattgtactt gtcgttttca
    26941 atcatattga tagtctgtct cgagacaccg atattcttgg cgagctcgag ctgggaaatg
    27001 cccagttcct tgcgaaattc tttcacacga ttcatctgtt cttctttctg atttatgtcg
    27061 tatatatttg actatattat agtcttttaa acataaagtg tcaagtattt ttgacatatt
    27121 ttttgaagaa atagtagtct ccttgtccta tttgtctgac aagtgcaagc tggtcggatt
    27181 tgtggtaaaa tagataagat atgacaaaag aatttcatca tgtaacggtc ttactccacg
    27241 aaacgattga tatgcttgac gtaaaacctg acggtatcta cgttgatgcg actttgggtg
    27301 gagcaggcca tagcgagtat ttattaagta aattaagtga aaaaggccat ctctatgcct
    27361 ttgaccagga tcagaatgcc attgacaatg cgcaaaaacg cttggcacct tacattgaga
    27421 agggaatggt gacctttatc aaggataact tccgtcattt acaggcacgt ttgcgcgaag
    27481 ctggtgttca ggaaattgat ggaatttgtt atgacttggg agtgtctagt cctcaattag
    27541 accagcgtga gcgtggtttt tcttataaaa aggatgcgcc actggacatg cggatgaatc
    27601 aggatgctag tctgacagcg tatgaagtgg tgaacaatta tgactatcat gacttggttc
    27661 gtattttctt caagtatgga gaggacaaat tctctaaaca gattgcgcgt aagattgagc
    27721 aagcgcgtga agtgaagccg attgagacaa cgactgagtt agcagagatt atcaagttgg
    27781 tcaaacctgc caaggaactc aagaagaagg gtcatcctgc taagcagatt ttccaggcta
    27841 ttcgaattga agtcaatgat gaactggggg cggcagatga gtccatccag caggctatgg
    27901 atatgttggc tctggatggt agaatttcag tgattacctt tcattcctta gaagaccgct
    27961 tgactaagca attgttcaag gaagcttcaa cagttgaagt tccaaaaggc ttgcctttca
    28021 tcccagatga tcgcaagccc aagatggaat tggtgtcccg taagccaatc ttgccaagtg
    28081 cggaagagtt agaagccaat aaccgctcgc actcagccaa gttgcgcgtg gtcagaaaaa
    28141 ttcacaagta agagggaaaa agatggcaga aaaaatggaa aaaacaggtc aaatactaca
    28201 gatgcaactt aaacggtttt cgcgtgtgga aaaagctttt tacttttcca ttgctgtaac
    28261 cactcttatt gtagccatta gtattatttt tatgcagacc aagctcttgc aagtgcagaa
    28321 tgatttgaca aaaatcaatg cgcagataga ggaaaagaag accgaattgg acgatgccaa
    28381 gcaagaggtc aatgaactat tacgtgcaga acgtttgaaa gaaattgcca attcacacga
    28441 tttgcaatta aacaatgaaa atattagaat agcggagtaa gatatgaagt ggacaaaaag
    28501 agtaatccgt tatgcgacca aaaatcggaa atcgccggct gaaaacagac gcagagttgg
    28561 aaaaagtctg agtttattat ctgtctttgt ttttgccatt tttttagtca attttgcggt
    28621 cattattggg acaggcactc gctttggaac agatttagcg aaggaagcta agaaggttca
    28681 tcaaaccacc cgtacagttc ctgccaaacg tgggactatt tatgaccgaa atggagtccc
    28741 gattgctgag gatgcaacct cctataatgt ctatgcggtc attgatgaga actataagtc
    28801 agcaacgggt aagattcttt acgtagaaaa aacacaattt aacaaggttg cagaggtctt
    28861 tcataagtat ctggacatgg aagaatccta tgtaagagag caactctcgc aacctaatct
    28921 caagcaagtt tcctttggag caaagggaaa tgggattacc tatgccaata tgatgtctat
    28981 caaaaaagaa ttggaagctg cagaggtcaa ggggattgat tttacaacca gtcccaatcg
    29041 tagttaccca aacggacaat ttgcttctag ttttatcggc ctagctcagc tccatgaaaa
    29101 tgaagatgga agcaagagct tgctgggaac ctctggaatg gagagttcct tgaacagtat
    29161 tcttgcaggg acagacggca ttattaccta tgaaaaggat cgtctgggta atattgtacc
    29221 cggaacagaa caagtttccc aacgaacgat ggacggtaag gatgtttata caaccatttc
    29281 cagccccctc cagtccttta tggaaaccca gatggatgct tttcaagaga aggtaaaagg
    29341 aaagtacatg acagcgactt tggtcagtgc taaaacaggg gaaattctgg caacaacgca
    29401 acgaccgacc tttgatgcag atacaaaaga aggcattaca gaggactttg tttggcgtga
    29461 tatcctttac caaagtaact atgagccagg ttccactatg aaagtgatga tgttggctgc
    29521 tgctattgat aataatacct ttccaggagg agaagtcttt aatagtagtg agttaaaaat
    29581 tgcagatgcc acgattcgag attgggacgt taatgaagga ttgactggtg gcagaatgat
    29641 gactttttct caaggttttg cacactcaag taacgttggg atgaccctcc ttgagcaaaa
    29701 gatgggagat gctacctggc ttgattatct taatcgtttt aaatttggtg ttccgacccg
    29761 tttcggtttg acggatgagt atgctggtca gcttcctgcg gataatattg tcaacattgc
    29821 gcaaagctca tttggacaag ggatttcagt gacccagacg caaatgattc gtgcctttac
    29881 agctattgct aatgacggtg tcatgctgga gcctaaattt attagtgcca tttatgatcc
    29941 aaatgatcaa actgctcgga aatctcaaaa agaaattgtg ggaaatcctg tttctaaaga
    30001 tgcagctagt ctaactcgga ctaacatggt tttggtaggg acggatccgg tttatggaac
    30061 catgtataac cacagcacag gcaagccaac tgtaactgtt cctgggcaaa atgtagccct
    30121 caagtctggt acggctcaga ttgctgacga gaaaaatggt ggttatctag tcgggttaac
    30181 cgactatatt ttctcggctg tatcgatgag tccggctgaa aatcctgatt ttatcttgta
    30241 tgtgacggtc caacaacctg aacattattc aggtattcag ttgggagaat ttgccaatcc
    30301 tatcttggag cgggcttcag ctatgaaaga ctctctcaat cttcaaacaa cagctaaggc
    30361 tttggagcaa gtaagtcaac aaagtcctta tcctatgccc agtgtcaagg atatttcacc
    30421 tggtgattta gcagaagaat tgcgtcgcaa tcttgtacaa cccatcgttg tgggaacagg
    30481 aacgaagatt aaaaacagtt ctgctgaaga agggaagaat cttgccccga accagcaagt
    30541 ccttatctta tctgataaag cagaggaggt tccagatatg tatggttgga caaaggagac
    30601 tgctgagacc cttgctaagt ggctcaatat agaacttgaa tttcaaggct cgggctctac
    30661 tgtgcagaag caagatgttc gtgctaacac agctatcaag gacattaaaa aaattacatt
    30721 aactttagga gactaatatg tttatttcca tcagtgctgg aattgtgaca tttttactaa
    30781 ctttagtagg aattccggcc tttatccaat tttatagaaa ggcgcaaatt acaggccagc
    30841 agatgcatga ggatgtcaaa cagcatcagg caaaagctgg gactcctaca atgggaggtt
    30901 tggttttctt gattacttct gttttggttg ctttcttttt cgccctattt agtagccaat
    30961 tcagcaataa tgtgggaatg attttgttca tcttggtctt gtatggcttg gtcggatttt
    31021 tagatgactt tctcaaggtc tttcgtaaaa tcaatgaggg gcttaatcct aagcaaaaat
    31081 tagctcttca gcttctaggt ggagttatct tctatctttt ctatgagcgc ggtggcgata
    31141 tcctgtctgt ctttggttat ccagttcatt tgggattttt ctatattttc ttcgctcttt
    31201 tctggctagt cggtttttca aacgcagtaa acttgacaga cggtgttgac ggtttagcta
    31261 gtatttccgt tgtgattagt ttgtttgcct atggagttat tgcctatgtg caaggtcaga
    31321 tggatattct tctagtgatt cttgccatga ttggtggttt gctcggtttc ttcatcttta
    31381 accataagcc tgccaaggtc tttatgggtg atgtgggaag tttggcccta ggtgggatgc
    31441 tggcagctat ctctatggct ctccaccagg aatggactct cttgattatc ggaattgtgt
    31501 atgtttttga aacaacttct gttatgatgc aagtcagtta tttcaaactg acaggtggta
    31561 aacgtatttt ccgtatgacg cctgtacatc accattttga gcttggggga ttgtctggta
    31621 aaggaaatcc ttggagcgag tggaaggttg acttcttctt ttggggagtt gggcttctag
    31681 caagtctcct gaccctcgca attttgtatt tgatgtaaga atggcaccct gatgtttcag
    31741 ggtgtttttg tgtttaaata cacaatgaaa atcaaagaac aaactagaaa gctaacttta
    31801 ggctgctcaa aatataatat attgaaacta gaatagtaca cctctacttc taaaacattg
    31861 ttagaaatcg atttgactgt cctgaacgat ttatcctgtt cttatttcat tttactatac
    31921 agtttcgagg ttgtagataa ggcgaagctg atgtggtttg aagagatttt cgaagagata
    31981 aaaaatattg gtcaattaaa gtcaaaatcc ttgacctttt ctgactaatg tagtatatta
    32041 tgaacgtaag gtaaatgaaa gccttactag aacacttatt taaagtaaaa tagaaagagg
    32101 tggggtctat gtttaatcta gaaatcttca gaagtaaaga tggtctactc ctgcttgaaa
    32161 aagaaaaacc agaaatagta cgtagggtag cggtttagct agtctaaatt ttttaaaaca
    32221 aaggtcaaag atagtcaata tcagtaatca taactaagta aacaaaaaga ggtaaagaat
    32281 atgaataaca actttaataa ttttaataac atggatgatt tatttaacca attgatgggt
    32341 ggtatgcgag gatacagttc tgaaaatcgc cgttacttaa ttaatgggcg cgaagtcaca
    32401 cctgaggaat ttgctcacta tcgtacgact ggtcaattac caggaaatgc agaaactgat
    32461 gtgcaaatgt cacaacaggc atcaggtatg aaacaagacg gtgtccttgc aaaactaggt
    32521 cgaaacttga cagcagaagc gcgtgagggt aagttggatc ctgttatcgg acgaaacaag
    32581 gaaattcaag aaacatctga aatcctctca cgccgcacca agaacaatcc tgttttggtc
    32641 ggagatgcag gtgttggtaa gacagcagtt gtcgaaggtc tagcgcaagc cattgtgaac
    32701 ggagatgttc ctgctgctat caagaacaag gaaattattt ctattgatat ctcaggtctt
    32761 gaggctggta ctcaataccg tggtagcttt gaagaaaatg tccaaaactt agtcaatgaa
    32821 gtgaaagaag cagggaatat tatcctcttc tttgatgaaa ttcaccaaat tcttggtgct
    32881 ggtagcactg gtggagacag tggttctaaa ggacttgcgg atattctcaa gccagctctc
    32941 tctcgtggag aattgacagt gattggggca acaactcaag acgaataccg taacaccatc
    33001 ttgaagaatg ctgctcttgc tcgtcgtttc aacgaagtga aggtcaatgc tccttcagca
    33061 gagaatactt ttaacattct tcaaggcatt cgtgacctct atcaacaaca tcacaatgtc
    33121 atcttgccag acgaagtctt gaaagcagcg gtggattatt ctgttcaata cattcctcaa
    33181 cgtagcttgc cagataaggc tattgacctt gtcgatgtaa cagctgctca cttggcggct
    33241 caacatccag taacagatgt gcatgctgtt gaacgagaaa tcgaaacgga aaaagacaag
    33301 caagaaaaag cagttgaagc agaagatttt gaagcagctc taaactataa aacacgcatt
    33361 gcagaattgg aaaagaaaat cgaaaaccac acagaagata tgaaagtgac tgcaagtgtc
    33421 aacgatgtgg ctgaatctgt ggaacgaatg acaggtatcc cagtatcgca aatgggagct
    33481 tcagatatcg aacgtttgaa agatatggct catcgcttgc aagacaaggt gattggtcaa
    33541 gataaggccg tagaagttgt agctcgtgct atccgtcgta accgtgctgg ttttgatgaa
    33601 ggaaatcgcc caatcggcaa cttcctcttt gtagggtcta ctggggttgg taagacggag
    33661 cttgctaagc aattggcact cgatatgttt ggaacccagg atgcgattat ccgtttggat
    33721 atgtctgaat acagtgaccg cacagctgtt tctaagctaa ttggtacaac agcaggctat
    33781 gtgggttatg atgacaatag caatacctta acagaacgtg ttcgtcgcaa tccatactct
    33841 atcattctct tggatgaaat tgaaaaggct gaccctcaag ttattaccct tctcctccaa
    33901 gttctagatg atggtcgttt gacagatggt caaggaaata cagtaaactt caagaacact
    33961 gtcattattg cgacctcaaa tgctggattt ggctatgaag ccaacttgac agaagatgcg
    34021 gataaaccag aattgatgga ccgtttgaaa cccttcttcc gtccagaatt cctcaaccgc
    34081 tttaatgcag tcatcgagtt ctcacacttg actaaggaag acctttctaa gattgtagat
    34141 ttgatgttgg ctgaagttaa ccaaaccttg gctaagaaag acattgactt ggtagtcagt
    34201 caagcggcta aagattatat cacagaagaa ggttacgacg aagtcatggg ggttcgtcct
    34261 ctccgtcgag tggttgaaca agaaattcgt gataaggtga cagacttcca cttagatcat
    34321 ttagatgcta aacatctgga agcagatatg gaagatggcg ttttggttat tcgtgagaaa
    34381 gcctaagata gaattttgag gataaaaaag aaggagccag ctgaaaaaaa ctggttcctt
    34441 ttgaggtacg acgggcatgt cgtacagtag aagtgtacta ttctagtttc aatccactat
    34501 agtagctcag aagtcggtac ttaaacgtgc tatatcaaaa ccagtccttg aaaaacgtgg
    34561 attggtttcg tgtttggatt attaccttga acgacatgcg ttaaaagtta gttgaaccgc
    34621 cgtatgccga acggcacgta cggtggtgtg agaggggcta gagattatcc cctactcgat
    34681 tttaaatcac atgacgttca aaggcatcat ctgaaatccc ttgttccaag atgagttttg
    34741 cccattcttt agcagagaag aggctgtggt ccttgtagtt tccgcaagat tcgatggttg
    34801 tccctgggac atcttcccaa gtagtagttt cagcgatttc cttgagcgaa tccttgataa
    34861 cagctgcgat tttagcactg gtgtgacgtc cccacataat catgtggaag cctgtgcggc
    34921 aaccaaatgg tgaacagtca atcatgccgt caatgcgggt acggatgagt ttggctaaga
    34981 ggtgctcgat agtgtgaagg ccggcagtag ggatagagtc ttcgtttggt tgcaccaagc
    35041 gaatatcata attggagatg atgtctcctt ttggtcctgt ttcttcccca atcaagcgaa
    35101 catagggtgc tttgacaatg gtgtggtcaa gttcaaaact ttcgacaata acttcttttg
    35161 acatggtaaa tcctttcagt tttcttctct cattatatca taaaggttgt tcctgagaca
    35221 gagagaaaac ctctccgagg ctagagaggt tgaaatcttt acttacgata taagcggtcg
    35281 tattggtagt atgggtcaaa ggttacgttg atacccagtt tacgaaggac attcttgtct
    35341 tcatcagtca agatgatggt tgagtgggct tcgcttcctt tgaggttgcc tagttcttcc
    35401 atagcgcggg cagcatcagg attttctgta gctgtgatag caagtgcaat caggatttca
    35461 tttgaatgaa ggcgtggatt gcggctaccg agatgatcga ttttaagacc ttggattggc
    35521 ttaacaactt caggttcgat tagttttact tctttagcga tgtcagctga ttttttgatg
    35581 gcgttgatca aggcagcggc tgtaggacca aagagttctg agttcttacc agtgacgatt
    35641 tccccatttg gcaattcaaa ggctagggct ggtccaccag tttcttctgc tttttggcgc
    35701 gcaacgacag caaccttacg gtctgcaggt gtgataccga ggtcgttcat gagcaactca
    35761 attttcttga cggcagcttc gccaactttt tcagctttga agtcaagaac tgtttgatag
    35821 taacggcgga tgatttcttg tttagaagct tcgacagcgg cctcgtcatc tgtaatagcg
    35881 aaaccaacca tgttgacacc catatctgtc ggtgaagcgt atggtgattt tccgagaata
    35941 cgttccgaca tgcgtttgag cactgggaag atttcgatat cacggttgta gttgacagtg
    36001 gtttctccat aggtttgaag atggaagggg tcaatcatgt tgacatcatc aaggtcagct
    36061 gtggcagctt cataagccaa gttaactgga tgatgaaggg gaagattcca aacagggaag
    36121 gtttcaaatt tagcgtagcc agatttgatg ccattgattt ggtcgtggta catattggac
    36181 atacacgttg ccaattttcc agaaccgggt ccaggagcgg ttacgacaat caagttgcga
    36241 ctggttttga tgtagtcgtt tttgcccatg cctcctgggg aaatgatgtg atccatatcc
    36301 gtaggatatc ctttgattgg ataatgaaga taagaatcaa ttccgttttt ctcaagttgg
    36361 ttgcggaagg catctgcagc gggttggcca gcgtattgtg taatgacaac ggaaccaaca
    36421 aaaatcccta attcattgaa tttgtcaatc aaacgaagaa cttcttggtc ataagaaatg
    36481 cctaagtcgc cacgtgcttt ggaatgttca atgttgctag cattaatggc aatcacaacc
    36541 tcaacctgct ctttcaattc ttgcaagagc ttgattttgt tgtcaggttc ataaccagga
    36601 aggacacgag cagcgtggaa atcttctaac attttaccgc caaactctaa gtagagcttg
    36661 ccgtcaaatt ggttaatgcg ctccaaaata tggtcgcgtt gtaaattcaa atactgttca
    36721 gaactaaaag cttgtttttt cattttttta cctctggact ctattataat aaaaaattgg
    36781 aagttaggaa actacggagc taaaaaagaa attaaaaaga ttaagcaaac gcttgcacaa
    36841 aattttaaaa agtgctatca tagactatag attattaaaa taatgaggta aacagatgca
    36901 agaaaaatgg tggcataatg ccgtagtcta tcaagtctat ccaaagagtt ttatggatag
    36961 taatggagat ggagttggtg atttgccagg tattaccagt aagttggact atctagctaa
    37021 gttaggaatc acagcgattt ggctttctcc cgtttatgac agccctatgg atgataatgg
    37081 ctacgatatt gctgattatc aagcgattgc ggctattttt ggaaccatgg aggacatgga
    37141 tcagctgatt gcagaagcta agaagcgtga tatccgtatc atcatggact tggtggtcaa
    37201 tcatacctcg gatgagcatg cttggtttgt cgaagcctgt gaaaatactg acagccctga
    37261 gcgagactac tatatctggc gcgatgaacc caatgaccta gattctatct ttagtgggtc
    37321 tgcttgggaa tacgatgaaa agtcaggtca atactatctc cactttttca gcaagaaaca
    37381 gccggatctc aactgggaaa atgaaaaact tcgccagaaa atttatgaga tgatgaactt
    37441 ctggattgat aaaggtattg gtggtttccg tatggatgtt attgacatga ttggcaaaat
    37501 tcctgacgag aaggtagtca ataatggtcc tatgctccat ccctatctca aggaaatgaa
    37561 tcaggcgacc tttggagata aggagctctt gacagtaggg gagacttggg gagcaacgcc
    37621 agagattgcc aagctctact ctgatccaaa ggggcaagaa ttgtctatgg tcttccagtt
    37681 tgaacatatc ggtcttcagt atcaggaagg tcagcctaaa tggcactatc aaaaagagct
    37741 gaatatcgct aagttaaaag aaatcttcaa caaatggcag acagagttag gagttgagga
    37801 cggctggaat tccctcttct ggaacaacca tgacctccct cgtattgtct caatctgggg
    37861 aaatgaccaa gaataccgcg aaaaatctgc caaagccttt gcaatcttac ttcatctcat
    37921 gagaggaact ccttatatct accaaggtga ggagattggg atgaccaact atccgtttga
    37981 aacactggat caagtagaag atattgaatc cctcaactat gcgcgtgagg ctcttgaaaa
    38041 aggtgttccg attgaagaaa tcatggacag tatccgtgtt attggacgtg acaatgcccg
    38101 tacccctatg caatgggacg agagcaaaaa cgctggtttc tcaacaggtc aaccttggtt
    38161 ggcggttaat ccaaattacg agatgatcaa cgtccaagaa gcgctggcaa atccagattc
    38221 tattttctat acctatcaga aactggtcca aattcgcaag gagaatagct ggctaattcg
    38281 agctgacttt gaattgcttg atacggctga taaggtcttt gcttatatac gtaaggatgg
    38341 cgaccgtcgc ttcctagttg tggctaactt gtctaatgaa gagcaagact tgacagtaga
    38401 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
    38461 aatcttagtt ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
    38521 atttaaaatt gaaatcgtat aaaaacaagg gaggactgta taaaaggcag aaatcctttg
    38581 ttttttataa ccaaggttta taaaccttca ttctcgaaat tcaattaact ttacaaattc
    38641 ccactattaa ggagaaagaa gacgaacata aagaagcgta tccttagtgc aggcctgact
    38701 tttacatctg atttgctttt agctgcttgc ggccaatcag gttcagatac aaaaacttac
    38761 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat
    38821 aatatagtca attgaaacaa gaacaggaca aaagagcctc ataaaaggta ttgcaacttg
    38881 gtaatacctt tttgaggtgc tttttgatat gagcccatgt tttctcaata ggattgtact
    38941 caggcgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcttcacac aagagttcta
    39001 gcttccccat tctatggaat cttgcattat ccataataat aaccgatggt gtggttaatg
    39061 ttggtaagag aaacttctga aaccaagctt caaaaaagtc gctcgtcatc atctcttcgt
    39121 aagtcattgg agcgattaac tcaccattca tttgttagac ctgcaaccaa agaaatcctc
    39181 tgatatcttc ttccagatac tttacctctt cttaactgac cttttaatga gcgaccatat
    39241 tctcgatgaa aataagtatc gaatcctgtt tcatcaatct aaacaggtgc taggtgcttt
    39301 aaactattaa aattcttaag aaataaggct actttttctg ggtcttgttc atagtaggtg
    39361 tggttctttt tttcgagtgt agcccatagc tttgagcgca tagtggatgg tagttggatg
    39421 acaggcaaat tcagaagcta tttcagtcaa ataagcgtct ggattattag taagatagtt
    39481 tttaagtcta tctctatcaa cttttcttgg ttttgttcct tttacttggt ggtttagctc
    39541 tcctgttttc tcttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
    39601 gtgtgatgct tctgttatac tacctgttcg ctcacaataa gagagaactt ttttacgaaa
    39661 atctattgaa tatgccataa aaagattata ccacattgtg tactatatta tattgaaact
    39721 agaatagtac acatctgctt ctaaaatatt gttagaaaac gatttgactg tcctgatcaa
    39781 tttgtcatgt tcttatttca ttttactata tttttggttc gcgggaagtc tactaagata
    39841 cttaaagatg cagatagtga aaataaaggt gtagacatta ccgtaaaaaa gtgatataat
    39901 cgtatgatgt tcaatgtata ggtgttaatc atgagtagac gttttaaaaa atcaagttca
    39961 cagaaagtga agcgaagtgt taatatagtt ttgctgacta tttatttatt gttagtttgt
    40021 tttttattat tcttaatctt taagtacaat atccttgctt ttagatatct taatctagtg
    40081 gtaactgcgt tagtcctact agttgccttg gtagggctac tcttgattat ctataaaaaa
    40141 gctgaaaaat ttactatttt tctgttggtg ttctctatcc ttgtcagctc tgtgtcgctc
    40201 tttgcagtac agcagtttgt tggactgacc aatcgtttaa atgcgacttc taattactca
    40261 gaatattcaa tcagtgtcgc tgttttagca gatagtgaga tcgaaaatgt tacgcaactg
    40321 acgagtgtga cagcaccgac tgggactgat aatgaaaata ttcaaaaact actagctgat
    40381 atcaagtcaa gtcagaatac cgatttgacg atcgaccaga gttcgtctta cttggcagct
    40441 tataagagtt tgattgcagg ggagactaag gccattgtct taaatagtgt ctttgaaaat
    40501 atcatcgagt cagagtatcc agactatgca tcgaagataa aaaagattta taccaaggga
    40561 ttcactaaaa aagtagaagc tcctaagacg tctaagaatc agtctttcaa tatctatgtt
    40621 agtggaattg acacctatgg ccctattagt tcggtgtcgc gatcagatgt caatatcctg
    40681 atgactgtca atcgagatac caagaaaatc ctcttgacca caacgccacg tgatgcctat
    40741 gtaccaatcg cagatggtgg aaataatcaa aaagataaat taacccatgc gggcatttat
    40801 ggagttgatt cgtccattca caccttagaa aatctctatg gagtggatat caattactat
    40861 gtgcgattga acttcacttc tttcttgaaa atgattgact tattgggagg ggtagatgtt
    40921 cataatgatc aagagttttc agctctacat gggaagttcc atttcccagt agggaatgtc
    40981 catctagact ctgagcaggc tctaggtttt gtacgtgaac gctactcact agccgatgga
    41041 gaccgtgacc gtggtcgcaa ccaacaaaag gtgattgtgg ctatccttca aaaattaacg
    41101 tcaaccgaag cactgaaaaa ttatagtacg atcattaata gcttgcaaga ttctatccaa
    41161 acaaatatgc cacttgagac tatgataaat ttggtcaatg ctcagttaga aagtggaggg
    41221 aattataaag taaattctca agatttaaaa gggacaggtc ggacggatct tccttcttat
    41281 gcaatgccag acagtaacct ctatgtgttg gaaatagatg atagtagttt agctgtagtt
    41341 aaagcagcta tacaggatgt gatggagggt agatgaaatg atagacatcc attcgcatat
    41401 cgtttttgat gtagatgacg gtcccaagtc aagagaggaa agcaaggctc tcttggcaga
    41461 atcctacagg caaggggtac gaatcattgt ctctacctct caccgtcgca agggcatgtt
    41521 tgaaactccg gaagagaaga tagcagaaaa ctttcttcag gttcgggaaa tagctaagga
    41581 agtggcgagt gacttggtca ttgcttacgg agctgaaatt tactacacac cagatgttct
    41641 ggataagctg gaaaaaaagc ggattccgac cctcaatgat agtcgttatg ccttgataga
    41701 gtttagtatg aacactcctt atcgcgatat tcatagcgcc ttgagcaaga tcttgatgtt
    41761 gggaattact ccagtcattg cccacattga gcgctatgat gctcttgaaa ataatgaaaa
    41821 acgcgttcga gaactgatcg atatgggctg ttacacgcaa gtaaatagtt cacatgtcct
    41881 caaacccaaa ctttttggcg aacgttataa attcatgaaa aaaagagctc agtatttttt
    41941 agagcaggat ttggttcatg tcattgcaag tgatatgcac aatctagacg gtagacctcc
    42001 tcatatggca gaagcatatg accttgttac ccaaaaatac ggagaagcga aggctcagga
    42061 actttttata gacaatcctc gaaaaattgt aatggatcaa ctaatttagg agaaatgatg
    42121 aaagaacaaa acacgataga aatcgatgta tttcaattat ttaaaacctt gtggaaacgc
    42181 aagctaatga ttttaatagt ggcacttgtg acaggtgcgg gggcttttgc atatagcact
    42241 tttattgtta agccagaata tacgagtacc acgcgaattt acgtagtgaa tcgcgatcaa
    42301 ggagacaagc cggggctgac aaatcaggat ttgcaggcag gatcttatct ggtaaaagac
    42361 taccgtgaga ttatcctttc gcagaatgta ttggaaaaag tagcgacaaa tttgaagttg
    42421 gatatgccaa caaaaacgtt agccagcaaa gttaaagtga ctgtaccaac tgacactcgt
    42481 atcgtctcaa tctctgtcaa agataaacaa ccagaagaag ccagtcgtat cgctaattct
    42541 ctacgagaag ttgctgcaga aaagatcgtc gctgtaacgc gagtatctga tgtaacgaca
    42601 cttgaagaag cgcgaccagc tacgactccc tcttctccaa atgttcgacg caattccttg
    42661 tttggttttc ttggaggagc agtcgtaaca gtaattgctg ttcttttgat tgagttgctc
    42721 gacacccgtg tgaaacgtcc tgaagatgtc gaagatgtac tgcaaattcc acttttaggg
    42781 gtcgttccag atttgaacaa aatgaaatag gaggaagtta tgccaacatt agaaatctca
    42841 caggcaaaat tggattttgt aaaaaaggca gaggaatatt ataacgcttt gtgcacgaac
    42901 ctacagttaa gtggagatga tttgaaagta ttttctatca cttctgtgaa actaggagaa
    42961 ggaaaatcaa cgacttccac caatatcgct tgggcttttg cgcatgcagg ttacaaaacg
    43021 ctgctgattg atggagatat tcgcaattct gttatgttag gtgtctttaa agcaagggat
    43081 aagattacag gcctgacaga atttttatca ggaactacag acctatcaca agggctttgt
    43141 gataccaatg tcgaaaatct ctttgtaatt caggctggct ctgtgtcacc gaatccgaca
    43201 gctcttcttc aaagtaagaa tttcagtaca atgcttgaaa ccttgcgtaa atattttgac
    43261 tacatcattg tagatactgc tcctgtcggt gtcgtgattg atgcggctat tattacgcga
    43321 aaatgcgatg cttctatttt agtgacggag gtaggtgaaa taaatcgacg ggatattcaa
    43381 aaagcaaaag aacagttgga acacacagga aagccgtttt tgggagttgt gttgaataaa
    43441 ttcgatactt cagtagacaa atacggttct tatggaaatt atggagatta cgggaaaaat
    43501 aaaaaatagg tcgggggatt agagatgaat ggaaaaatag taaagtcttc attggccata
    43561 atccagagtt ttcttgttat tttattgact tatctactta gtgctgtgag agaagcggag
    43621 attgtttcaa caacagctat tgcactttat atcctccatt attttgtctt ttatatcagt
    43681 gattatggac aggatttctt taaaagagga tatttgattg aacttgtcca gacattgaaa
    43741 tatatcctat tctttgcact agcgattagt atttctaatt ttttcttaga ggatcgattt
    43801 agtatttcca gacgaggcat gatttacttc ctcacattac atgctctctt agtctatgtg
    43861 ctaaacctat ttatcaagtg gtattggaag cgggcttatc ccaactttaa aggaagtaag
    43921 aagattctcc tacttacagc aacttctcgt gtcgaaaagg tactggatag attaatagaa
    43981 tcaaatgagg ttgttgggga gttggtagcc gtcagtgtct tagataaacc agattttcag
    44041 catgattgtt taaaggtagt agcagagggg gagatagtaa actttgcgac tcatgaggtg
    44101 gtcgatgaag tctttatcaa tcttccaagt gaaaaataca atattggaga gcttgtctct
    44161 cagtttgaaa cgatgggaat tgatgtaaca gttaatctaa atgcttttga tcgtagtttg
    44221 gcacgtaaca agcaaattcg tgagatggca ggattaaacg ttgtgacttt ttctacaaca
    44281 ttttataaga ctagtcatgt aattgctaag cggattattg atatcatggg tgcattggta
    44341 gggctgatac tatgtggttt agtcagtatt gtactggttc ctttgattcg aaaggatggg
    44401 ggctctgcta tttttgctca gacgcgtata ggaaaaaatg gtcgtcagtt cactttttat
    44461 aagtttcgct ctatgtgtgt agatgccgag gcgaaaaaaa gagaactcat ggaacaaaat
    44521 accatgcagg gtggaatgtt taaggtggac gatgatcctc gtatcacgaa aattggttgt
    44581 tttatacgga agactagctt ggacgagcta ccacagtttt ataatgttct aaagggagat
    44641 atgagtttgg ttggcacacg gccaccaaca gtggacgagt atgagcacta taccccagaa
    44701 caaaagcgtc gtctgagttt taaacctggc ataacagggt tatggcaggt cagcggacga
    44761 agtgagatta agaattttga tgaagttgtc aaattagatg tagcctatat agacgattgg
    44821 acaatttgga aagatattga aattttattg aagacagtta aagttgtatt gatgaaggat
    44881 ggagcgaagt gatttttgcc cttcggtctt gttaggagag atatgaaaca gtcagtttat
    44941 atcattggtt caaaggggat tcctgccaag tatggaggat ttgaaacctt tgttgagaaa
    45001 ttaacagaat atcaaaaaga tggtaacatc caatactatg ttgcttgcat gcgcgaaaat
    45061 tctgcaaagt caggatttac agcagacaca tttgagtaca acggtgctat ttgttacaac
    45121 attgatgtgc ctaatattgg tcctgctaga gccattgctt acgatattgc agcggtcaat
    45181 aaggctattg aattgtctaa gggaaacaag gacgaggctc ccatttttta cattctagct
    45241 tgtcgtatcg gaccttttat ttctggactt aagaaaaaaa ttcgttcgat cggaggccgt
    45301 ttgctggtaa atccagatgg tcatgagtgg cttcgagcta aatggagctt gccagttcgg
    45361 aagtattgga aattttcgga acagttgatg gtcaaacatg cagatttatt agtctgcgat
    45421 agcaaaaata tcgaaaaata tattcgagag gactataaac agtatcagcc caagacgacc
    45481 tatatcgctt atggtacaga tactacccct tcaagtctga aatcagaaga tgccaaagtt
    45541 cgaaactggt atcgtgaaaa gggagtaagc gaaaatggct attatctagt ggtgggacga
    45601 ttcgttcccg aaaacaacta tgaaaccatg attcgtgaat ttatcaagtc taagtccaat
    45661 aaggactttg tccttattac aaatgtggaa cagaataaat tttacgatca gttgctcaag
    45721 gaaacaggtt tcgacaagga tctaagagtc aaatttgtgg gaacagtcta tgaccaagaa
    45781 ttgctcaagt atatccgtga aaatgctttc gcctatttcc atggacatga agttgggggt
    45841 accaatccat cgcttcttga agctttagca tccactaaac tcaacttgtt gttggatgtc
    45901 ggctttaacc gtgaagttgg tgaagacgga gccatttatt ggaaaaaaga tgagctagcg
    45961 catgtaatcg aagaagtgga acgatttgat gaaggtgata ttacggaatt agacgaaaag
    46021 tctagccaac gaattgcgga tgcatttacg tgggaaaaga ttgtgtcaga ttatgaggaa
    46081 gtgtttactg tatgaaaatt ttgcattata ctttaggctt tcaaccatca cgtacaggtg
    46141 gtcttgtcaa gtatgctgag gatttgatga ctcaacaagc tacagatgga catgaagtaa
    46201 tcgcattata tccaggagaa atctcaatta tatttaggca ggttagaata aaaaaagcag
    46261 agaatcgaaa attccaatgc tataaaataa taaacagcct acccttggct ctatttggtg
    46321 gtatttcaga accagatgaa tttatgaaga gttgtgataa agcttcttat aggaaatttt
    46381 tgaaaaatat taaggtagat gtaattcaca ttcactcgct tataggatta cataaggaat
    46441 ttattgaagt tgcaaaagaa ttaggaatta aaactgtatt tacaagccat gattattatg
    46501 gtttagcgcc agttccgcat ttttatttta acggagtaga ttatagtagt aataatacta
    46561 atttagcatg gaacatcatg tcctctaatg ctcttagtgt aaaaaaactt cgattctttc
    46621 aagtctcttt ttacccaaca attcggaaat tgatgaaaat gcttgggaaa aatccaaagt
    46681 ccaagaaaaa cttagtaatt cgtgatatca cggaggctat tgattatagt gctctccgct
    46741 cttattataa agcaatgttt gggttaatag atgcttacct tttcaatagt cagttagcta
    46801 aggaagttta tgaagctaat catataatac ctaaaaacaa tatcatagtg tccatttcta
    46861 acagctcaat aagtaatcat aatattcgtg ttagttccgg tgagaaaaca gtggtagctt
    46921 atattgggcc tgatgaggaa tataaggggt attttgattt tctagatata gttaatgatt
    46981 tagatcagga aaagtatgat attaaaacat atggacattt tccaaatgaa gattgtccac
    47041 cttatatcca acagaacggt tatttcacaa aagacacggt tggaagcgtt tattccaata
    47101 tagatatttt gattgtgccg agtaggtgga aggaaacatt tggtttgatt agtatagagg
    47161 cgctatcgta tgatgtgaat gtttttgtga gcaaaaatgt gggctctaaa gatttggttt
    47221 cagaagaaca tatctttcat aataaagacg atttgttaaa aaaaattcaa tatgtaaaat
    47281 tcgagaatgt aaaattcaaa acgatgaaag agcatatggt ggagattata aattactatg
    47341 aaaggattac aaatgataat caaaagatta attaagacaa ttacaggtaa agaaattgat
    47401 cttcaccctg atatcccaat aacttacatt cttcagagag gttttcaata cggtttgggt
    47461 cttagtcgag ggttgttacg tggtattggt ctaggaaaaa aaggcaaacg attatttatt
    47521 ggacgtgggg taacccttct cgcaaaacgc aagttatatg ttggaaacaa tatccgaatc
    47581 ggcaaatatg tgagcataga ttgcctttca aaggatggga tccaaattgc ggataatgtt
    47641 aagataggag attactcgca aataattggt acaggttcag taaaaaatat gggtattggg
    47701 ctcaaaattg gaaagaactc ttctttctca gaatatagtt tattcggttc tgcaggtggg
    47761 attactatcg gaggagatgt tattgctgga caaaatgtac gttttcatgc tgagaatcat
    47821 agctacgaag tgttgcatat accaatcaga gagcaaggtg ttaatcgtaa agggatatcc
    47881 gttggtgaca attgctggat tggggcagga gctgtttttt tagatggatc tagtatcggt
    47941 tcaggttgta tcgttgcaac gaatgcggtt gttactaaga aatttccaga taatgtaatt
    48001 attggtggag tgccagctaa aattttaatg gaaagaaagt agtattaaat taattgtata
    48061 aatggaggga aatgatatgt ctaaaatgaa gattgctgta gttgggacag gttatgttgg
    48121 tttatccatt tctgtgttac ttgcacaaca ccatcatgta gtagcagtag atattgtaaa
    48181 agagaaagta gaattaatta ataaaagaat ttcacctatt caggatgatt ttattgaaag
    48241 atatctttca gaaagtaatt tagatttagt tgcaacaata gacgctgaaa cagcttataa
    48301 agatgcctct tttatcgtag tagcgacacc aacaaattat gacttagaaa gaaatttttt
    48361 tgatacatca acagttgaat cggtcattca acaagttcag aatatgaatt ctacagcaac
    48421 tatagtaata aaatcaacag tccccgtggg ctttaccgat tcaattcgta aaaaattagg
    48481 aatttcaaat cttctattca gtcctgaatt tttgcgtgaa tcaagggcac tttatgataa
    48541 cttatatcca agtcggatca tagttggaac agatttaagt aatcaaaaat tagttgaaaa
    48601 agcccaagtt ttctctaatc ttttagtgca aggtgccatt aaaaaagata tccctatttt
    48661 aactatggga tttactgaag ctgaagcagt taaattattt gctaatacct acttagcatt
    48721 gcgggtatca tattttaatg aattagatac ttatgcagag atcaaagggt tagatactca
    48781 aaaaataatt gaaggtgtta gtttagatcc tcgtatcgga acccattata ataatccgag
    48841 ctttgggtat ggtggatatt gcttaccaaa ggatactaag caacttttag ccaattataa
    48901 gaatgtccca gaagagctta ttggagctat agtacgaagc aatacaacac gtaaagattt
    48961 tattgctaat caagttctta aagtggtgaa ttataatata ccagaagacg atattcctac
    49021 taaacagatg gagaaagaag ttgttattgg aatataccga ttaactatga aaagtaacag
    49081 tgataacttt cgtcagagtt caatacaagg agttatgaaa cgtattaagg atagaggagt
    49141 taaagtaatc atttttgagc ctactctaaa agatagtgat acattctttg gaaacgctgt
    49201 tataaatgat ttagaagagt tcaaagtaaa gtgtgatgtg attattgcaa atcgttatga
    49261 tgaaacgttg aatgacgtta aggataaagt atatacacga gatattttta gaagagattg
    49321 ataaaaatat gaaaaaagta ttaattgttc gaagtggacc ttaccaagtc aatccggaag
    49381 gatataatct tcaagaactt ggtttagcct ccgctatcag tcagcaaggc taccagtgtg
    49441 atgtcatgta ttatcacaaa acaaagaact atgatcaatt atatgagaaa aatggggaac
    49501 aaattaaaat attctggagg aggggaataa gattatttag aagtggaatt tatccccaga
    49561 ttttaagaga gaaatttttg aatcagtatg ataagataat tatttctgag tacagccaga
    49621 ttatggcagt tttattgtct agaattcatt ccaatgtata tatttataat ggcccatact
    49681 ataatctatt taagattccc attattgaac ctatatacga ttttcttttt gtagaaatgc
    49741 tcaataagag aaccaaaaca gttttctgca agacagaaaa agcagagtgt tatcttaaaa
    49801 acaaaggatt caatgattgt aaagtagtgg gcgtaggtct agatattgag aagtttgaac
    49861 aagaagagga acctacagag gatactatag agcttttaag aagaatggag aataaacaaa
    49921 atattcttta tgtaggttca ctatcaaaaa gaaaaaacac agctcagtta attagaattt
    49981 ttaatatttt aaaatctaaa agtggtaaga aaaatgaact tcaattggta ttgattggta
    50041 aggatgagga taatattgtt gaaaaaatta actattcacg gtttaaagat gatattattt
    50101 atcaacctta tttaaagaat tctcagcttc aatttattta cccatcatca caactacttg
    50161 tgctcccgtc agttcaagag atttttggta tggtattact tgaggcaatg tattttaagt
    50221 tgcctgttgt ttccagtgca agtgctggag gagagacact gattcaagat ggtataaacg
    50281 gtaaaattgt gaatgatttt aatgatgaac actgggtgga ttgtatagaa aatctattaa
    50341 ataacccatt ggaattgaaa cggcttggag aatgtgctca taagcgcatt acggaacagt
    50401 ttatgtggtc ttcaattgcg agaaaaataa ttgagacatt tgatgaaagg taagacttgc
    50461 tatgaatttt tgttttgtga ttttgcatta tcgtaccagc aatgacacta tagagtgtat
    50521 caaatcgatt caaaagcttg agggagatta taaaattgta attgttgata atgcttctca
    50581 aaatggcagt atagaaaggg tagaagcctt atttgcaaat aatgacgaga tagttataat
    50641 aaaaaacacg aaaaacttag gatttgctgc tggaaataat attggatacg cctacgctag
    50701 gactcaaata aaagctgata tgattgctgt acttaataat gatattgtta ttaagcaaaa
    50761 agatttcatc aatcgtatat ttgaactcta tagaaattct cagtttcata tcgctggtcc
    50821 agacattgtc tctcttgtag atggtcatca tcaaagtcct gttgttgaga agattaattc
    50881 tatatctaag gctaataaag aactttttaa atatagaatc ttgaggatta ttaataaaat
    50941 aggattatat gagctgatga ctagacagcc aaaaaaagaa ttaaatagaa taagtgttgc
    51001 agaccctatg agatatcagg aaaatgttat tttacatggg agttttgtaa ttttttcacc
    51061 gttgtatgtt tcagaggagg agtgtgcttt cagaccggat acattcatgt atatggaaga
    51121 gcctattcta tatgaatatt gcatgcttaa aaattataag acagtatttg atccttctat
    51181 tgtaatttat cataaagagg actcatcaac aaattcgttg tataatgcag catatgcaaa
    51241 aagagagttt gtttttaaaa atatgattag atctctaaag atttatagaa gtctattgaa
    51301 gtagtaaact aaggaaagga taataattag aaattgaatc ttagtatgtt agccttgaca
    51361 ataggaacag tggtatttgt taaaaaaacg tataggacgt ttctcaatcc cataatttta
    51421 tttgtaattt tgtggtttat tataacaact ttgtcaagtt taaaactatt ccaacttttc
    51481 gagattagta ctcacacaca acaaattatt ttgcttggga cttctctatt tgttataggg
    51541 ggagggatag caatttggtt tcgggataaa ttttatttta aagttggcgg taactcatat
    51601 tttacaacag actttgaaat taattataat ttgttctttt tgctaggtat catttgcctt
    51661 ttctattatt tgccagattt cttttcctca ctggtatcat taataagagg tgggaattta
    51721 aacttagtta gacaatctgc gcaggatgca gtagatacca gtggattaaa gaatttcatt
    51781 ggaacattta ttgttagtcc tagtgccatg gtattagaaa tattaggagt attagatttc
    51841 tggagcaata aaaaaggtag aaaactattt tatcttagtt tagctgtcat ttttgtaaga
    51901 gttattgcag atgctggtag aacacctcta tttaatgttg tcatatattt attacttact
    51961 gttttagcaa ataggttctc tgaaaaaact gaaaagaaga gaaaagttag taaaattaag
    52021 atagtaaatt atggtatgct aggttcaatt atcttatggc tatcaacttt atctaggaca
    52081 acaacctccg tttataggat tctttatttt tatttcgcaa tgtccccaat attattagaa
    52141 aagtggagta gtgtacttga ttctgaaaaa ttagtaacaa agggtttggt ttcgttgaac
    52201 ggtttctttt tttcaatctc atatgtactt aaaaatctgt ttagaataga ttattcgcaa
    52261 agagtattag aagcatacac aatgattgcg aatactgatg caatctggta taatattgca
    52321 cctggtttga ccaaggcaaa tgcatatgtc tctctgtttt ggttctttta tgcggatgga
    52381 cgtttactag gagttttaat aggatccctt ctatatggta ccttttgtgg ttatatcttt
    52441 tgcaggtata tccagcaaca aaataaaaag aatttggcta tgttactatt tatttatcaa
    52501 ggtgtttttt tctcttttat tagatttccg ttttcaaaat caaattatgc aattgcattc
    52561 gtactcttat tattttttgc ttttaagaag aaaggaatag agaaaagtgt ttaatatcaa
    52621 tgaccagtct attatttatg ttgcatgtcc ttattttaat aaaacaggtg gaacggagct
    52681 tgtccatcaa ttagtttatt ctattaatca ttttgggggg aaagctatcg ttgcttatta
    52741 tggtagtgaa agtgctccaa ataaggtgaa tcctgcgttt agagaatatg tttctacgtt
    52801 tgttgatata aaagatgtta ttgactctct tgataatatt attattttac cggaaattaa
    52861 tccggattta gctgctaatc tagagtctat tcaaaaagca gtatggtgga tgagcgttga
    52921 caattatttg aagcgtaatg gtattttagg ttccttggaa cattttggac ttttacgaac
    52981 aattaaatta tttgtaaaag gaaatattaa aataggtgga tatagaatag ataaagagat
    53041 tccccatctt tatcaaagtg aatacgccaa gcaatttctt ctagctaaag gtgtcaaaaa
    53101 gtactataga ttgtctgatt atttaaacga gtcttatatt cagcgatcta tttcaacaga
    53161 cactaaaaaa gatgttattc tttacaatcc taaaaaaggg attgaattta ctcgtgagct
    53221 aattaaacag gctccagaat taacgttctc tccaattgag aatatgtcaa ctgaacaggt
    53281 gaaaaaatta ctttcaaaaa gcaaagtata tattgatttt ggcaaccatc ctgggaaaga
    53341 tagattccca cgggaggcag cgatatcagg ttgttgtgtg ataactggga aacgaggttc
    53401 tgcaaaatat tataaggata ttcctattcc agattcatac aaatttgaag acactgttga
    53461 aaatatcccc aacattattg agaccctgaa atcatgctta aaaaattatg acaaacatac
    53521 tgttgacttt gagaaatatc aacaatatat taaatctgaa catgatttat ttgaaagaga
    53581 tgtgaaagaa ttattcacta ggaatagggg ttaaggttat gtcaaccaga aattcactta
    53641 ttaaaaattc tctttataat gttgcttata gaatgttaaa tatcatattt ccattagtat
    53701 ccgcaacata tactgcacgg ataattttag ctagtggagt tggggaggtc tcgtttgcac
    53761 aaaatgttgt ttcttacttt acaacgatag ctgctatggg tattccaaat tatggtatac
    53821 gagaaattgc taaaactaga aataaagcag aggctacgaa taaagttttt tcagagctat
    53881 ttctgattaa tggattgtct acattactgt gttctatagt atatttaatt ctgattttga
    53941 cattcaatag catttttgat aatacatcaa tgtatcttgc tgtgggttta acattagtgt
    54001 ttaacttcct taatatcgat tggttctatc aaggaaaaga ggactatgca tacatcacga
    54061 aacgtagttt cagtataaaa cttatttctc tttttagttt atttattttt gttagagata
    54121 ctgacgatgc agttaactat gcattgattt ctagctt
//
LOCUS       DAVLZG010000005        48672 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLZG010000005 DAVLZG010000000
VERSION     DAVLZG010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.005"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(266..1252)
                     /locus_tag="VYO72_000310"
     CDS             complement(266..1252)
                     /locus_tag="VYO72_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1706753.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1262..2062)
                     /locus_tag="VYO72_000311"
     CDS             complement(1262..2062)
                     /locus_tag="VYO72_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1706754.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2315..3157)
                     /locus_tag="VYO72_000312"
     CDS             complement(2315..3157)
                     /locus_tag="VYO72_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1706755.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3159..4451)
                     /locus_tag="VYO72_000313"
     CDS             complement(3159..4451)
                     /locus_tag="VYO72_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1706756.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4562..5833)
                     /locus_tag="VYO72_000314"
     CDS             complement(4562..5833)
                     /locus_tag="VYO72_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1706757.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6382..7899
                     /gene="malQ"
                     /locus_tag="VYO72_000315"
     CDS             6382..7899
                     /gene="malQ"
                     /locus_tag="VYO72_000315"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1706758.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7925..10183
                     /gene="glgP"
                     /locus_tag="VYO72_000316"
     CDS             7925..10183
                     /gene="glgP"
                     /locus_tag="VYO72_000316"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1706759.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11228..11800)
                     /locus_tag="VYO72_000317"
     CDS             complement(11228..11800)
                     /locus_tag="VYO72_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706760.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            complement(12425..13273)
                     /locus_tag="VYO72_000318"
     CDS             complement(12425..13273)
                     /locus_tag="VYO72_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1706761.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13425..13703
                     /locus_tag="VYO72_000319"
     CDS             13425..13703
                     /locus_tag="VYO72_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706762.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13705..15768
                     /locus_tag="VYO72_000320"
     CDS             13705..15768
                     /locus_tag="VYO72_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1706763.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15846..17102)
                     /locus_tag="VYO72_000321"
     CDS             complement(15846..17102)
                     /locus_tag="VYO72_000321"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1706764.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17244..19709
                     /locus_tag="VYO72_000322"
     CDS             17244..19709
                     /locus_tag="VYO72_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1706765.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLCFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLATADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19774..20685
                     /locus_tag="VYO72_000323"
     CDS             19774..20685
                     /locus_tag="VYO72_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1706766.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20915..21613
                     /gene="dapD"
                     /locus_tag="VYO72_000324"
     CDS             20915..21613
                     /gene="dapD"
                     /locus_tag="VYO72_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1706767.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21681..22811
                     /locus_tag="VYO72_000325"
     CDS             21681..22811
                     /locus_tag="VYO72_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1706768.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22823..23362
                     /locus_tag="VYO72_000326"
     CDS             22823..23362
                     /locus_tag="VYO72_000326"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1706769.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23346..24023
                     /locus_tag="VYO72_000327"
     CDS             23346..24023
                     /locus_tag="VYO72_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1706770.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24090..24989)
                     /gene="galU"
                     /locus_tag="VYO72_000328"
     CDS             complement(24090..24989)
                     /gene="galU"
                     /locus_tag="VYO72_000328"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1706771.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(25011..26027)
                     /locus_tag="VYO72_000329"
     CDS             complement(25011..26027)
                     /locus_tag="VYO72_000329"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1706772.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26239..26679
                     /locus_tag="VYO72_000330"
     CDS             26239..26679
                     /locus_tag="VYO72_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1706773.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26802..27218)
                     /locus_tag="VYO72_000331"
     CDS             complement(26802..27218)
                     /locus_tag="VYO72_000331"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1706774.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(27286..27936)
                     /gene="phoU"
                     /locus_tag="VYO72_000332"
     CDS             complement(27286..27936)
                     /gene="phoU"
                     /locus_tag="VYO72_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1706775.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27951..28703)
                     /gene="pstB"
                     /locus_tag="VYO72_000333"
     CDS             complement(27951..28703)
                     /gene="pstB"
                     /locus_tag="VYO72_000333"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1706776.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28705..29520)
                     /gene="pstA"
                     /locus_tag="VYO72_000334"
     CDS             complement(28705..29520)
                     /gene="pstA"
                     /locus_tag="VYO72_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1706777.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDIMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29513..30376)
                     /gene="pstC"
                     /locus_tag="VYO72_000335"
     CDS             complement(29513..30376)
                     /gene="pstC"
                     /locus_tag="VYO72_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1706778.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30494..31369)
                     /locus_tag="VYO72_000336"
     CDS             complement(30494..31369)
                     /locus_tag="VYO72_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1706779.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31536..32867)
                     /locus_tag="VYO72_000337"
     CDS             complement(31536..32867)
                     /locus_tag="VYO72_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1706780.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32868..33575)
                     /locus_tag="VYO72_000338"
     CDS             complement(32868..33575)
                     /locus_tag="VYO72_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1706781.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33659..34144)
                     /locus_tag="VYO72_000339"
     CDS             complement(33659..34144)
                     /locus_tag="VYO72_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1706782.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34130..34669
                     /locus_tag="VYO72_000340"
                     /pseudo
     CDS             34130..34669
                     /locus_tag="VYO72_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34984..36675)
                     /locus_tag="VYO72_000341"
     CDS             complement(34984..36675)
                     /locus_tag="VYO72_000341"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1706783.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36811..37257
                     /gene="argR"
                     /locus_tag="VYO72_000342"
     CDS             36811..37257
                     /gene="argR"
                     /locus_tag="VYO72_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1706784.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37308..39842
                     /gene="mutS"
                     /locus_tag="VYO72_000343"
     CDS             37308..39842
                     /gene="mutS"
                     /locus_tag="VYO72_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1706785.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39989..41683
                     /gene="patA"
                     /locus_tag="VYO72_000344"
     CDS             39989..41683
                     /gene="patA"
                     /locus_tag="VYO72_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1706786.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(42013..42276)
                     /locus_tag="VYO72_000345"
                     /pseudo
     CDS             complement(42013..42276)
                     /locus_tag="VYO72_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            42470..44236
                     /gene="patB"
                     /locus_tag="VYO72_000346"
     CDS             42470..44236
                     /gene="patB"
                     /locus_tag="VYO72_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1706787.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTENKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44375..45064
                     /locus_tag="VYO72_000347"
     CDS             44375..45064
                     /locus_tag="VYO72_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1706788.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQIGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            45068..45247
                     /locus_tag="VYO72_000348"
     CDS             45068..45247
                     /locus_tag="VYO72_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706789.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45234..46583
                     /locus_tag="VYO72_000349"
     CDS             45234..46583
                     /locus_tag="VYO72_000349"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1706790.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46707..48167
                     /locus_tag="VYO72_000350"
     CDS             46707..48167
                     /locus_tag="VYO72_000350"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1706791.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYSRHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            48181..48615
                     /locus_tag="VYO72_000351"
     CDS             48181..48615
                     /locus_tag="VYO72_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1706792.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        14342 a         9255 c        10562 g        14513 t
ORIGIN      
        1 cgtcagtttc atctacaacc tcaaaaccat gttttgagct gacttcgtca gttctatcca
       61 caacctcaaa acagtgtttt gagcaacctg tggctagctt cctagtttgc actttgattt
      121 tcattgagta taaaaagatc ttgggtaaca actcaatttc agtagaaaag gaagtaaatc
      181 ttcccacaat aaaacgcata gtatcaagtt ttttcaatac ctgatactat gcgtttttgc
      241 ttttaacgac tttttgccca gtctcttatt tttcgataat tttgtgggcg atcaattgac
      301 ggtaacaaat ttgtttattg tttttattat cattaataat ctggagaata gtttcaaggg
      361 aaacacgacc aagctctaaa ctattgatat cgacataggc tgccaagttg agcttgggat
      421 taaccgagtc aaagctgaga acagggacat ccagctggtg tttggcaata tagttacaaa
      481 caccttcagc taggaggcta tcggttgtga tgatagcatc aatttgtgga tcgtgcttga
      541 ataatcgctt gctaaattta tagccctttt cttccagaaa ctcgtcggca aagtagatgc
      601 gattgttgtc agtggtaagt ttgtaatgtt taagcgcctg ttcatagcct gttaaacggt
      661 ctttggtcac gaagagcttt ttacttcctc cgataaaggc aatgcgtttg cagccttttt
      721 tgatgaaata ttcagtcgca tcaaaaccag cttgaacatt gtcgttgtcg acaagtggga
      781 tgaaaggaga tagagattta cctaagataa ggaaggggaa ctgttcttct gcgacgagtt
      841 ttacgagagg gtcttcttct tgggcataga gaaagattag cccatctaca cgcttgccgt
      901 agaccatttg tgaaatagcg ttgagacgct ccttctcatc tttccctgtt gctatctgaa
      961 tggcatagtg gttttcagat gcgacttgag agatgccacg tagaaccgat ggaaagaaag
     1021 gattctggta gaaggcgtct gagtcatcag gaagaactaa tccgataacc tgagtatagc
     1081 tgcttaccaa gctacgagcg ttgaggtttg ggtggtagtt gagttccttc atagctttgc
     1141 gaacgcgttt ttttgtttcg tcgctaatgg ttgatttatt ttgaataaca cgggttacgg
     1201 ttgaaggcga aacaccagca gccttggcca cgtctttaat cgtaacgggc ataaaaatct
     1261 cctatttatg gtaatttgga tcacggaaat gtgttttata aaagatagtg accagataca
     1321 gaacaaaaag aatattttgt acagtaatca gggttgtcat attttggcca aataatccca
     1381 aaataagtgt aatcagagtc ggcaatccta aacagttcaa gataaagtga tagcactctt
     1441 taaaggttct aaatgaaaag aggcgtgatt tcttagtgat ataaaggaga agactagctc
     1501 ctagagagac gataaagaaa ttcaaaccaa agaggaagct cgcaccgaga actaggaaga
     1561 ggctgatata gacacgattt tgttggtacc agtctttaga aattgcttgg gtcaagctgt
     1621 ctttgctttt gaaactctca gtctgaatgg ctcggtaaga gatgcgggtc agttccttgc
     1681 tttccttgct gatgactagc tcatttgtat cgaaatgcag ttgcaagtcc ttaggtaatt
     1741 ccttgatttg acttggacca atcacaacag aaggggcttg actagctgtt ccagtataag
     1801 ttaatgtgcc atcgacaatt gtagcatgtt cagagagatc ctggacaacc tcatttgtca
     1861 gaggttcata gacattatcg ataaaagttt ctagcggata ggtctcctgg gagctgtttt
     1921 ggatagcaat gggtaccata gacaagctga taaggaagat actggtaaag agaagttgaa
     1981 accagttgag ctcgaaacgt ttggacaggg gcttacgaaa cccccaaata cttgaaaaat
     2041 aggaaaatgg atatggaagc ataggtatct ttctaaaagg tgttttctat atgagtatta
     2101 ttatatagag aaatgctctt tatttcaagt ctaggagaaa aattgcttgc tacaaggata
     2161 ttatttacag tgacaattgc taataatcaa tgaaaatcaa agtgcaaact agccacaggt
     2221 tgctcaaagc acaactttga ggttggagat aaagctgacg tggtttgaag agattttcga
     2281 agagtataaa atgaaaaagg gtggcgggga taaattatcc cttgtcgcca ccacttgtaa
     2341 gtcctgaaac aaagttcttt tgtaggaaga agaagagaat acagattgga agggcgatga
     2401 ggatagcacc tgctgagaag taggcaatct tcaagttttt cgcattgtta acgaaggttt
     2461 ggagacctac ggcaacagta aagtattctt tctcacgaag caagaaacta gagaggatgt
     2521 agtccccgaa aggtcccatg aaggcccaga gagcttgtac ggcaaccatt gggcgaacaa
     2581 gtggtagaac aatttgccag aagcggcgga agtgtcctgc accgtctagt tttgcagatt
     2641 cgtctaaaga cattggcact gtatcgaagt agcctttcat gagccaagca ttcatcggga
     2701 taccaccacc aacgtagagg aagatgagga accagttgtg gttaagggcg ttcaacataa
     2761 gcgccataac gaagaaggct gtcaaagcgg ccatagttgg caccatttgg atgatcaaga
     2821 agaagaccaa actttgttta cgagccaaga agttgtaacg gctgtaggca taaccagcaa
     2881 gtacgatgat acttgtttga acagccatgg taattaaggc gataatcaaa gtgttgaggt
     2941 accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa gttatcaaaa ttgaggtcga
     3001 tattagtatc tagtttaaag gctgagacgt tacctgcttt aaaggctgac ataatggtaa
     3061 tcaacagtgg atagataatt acaattgata gaccaatcag gtaaaggtaa gtaaggcttt
     3121 gagtcagtct acgtttgagt ttaattgagt tattcatctt agacgtcctc catatcaaat
     3181 gcgtgtagtt tcttgaatgc gatcatagag attgagatga caatgataga gataatcaag
     3241 gtaacagctg ccgccattga gtattgagga gatgtacctg ttgtcaaacg gtagatccat
     3301 gagatcaaga tatcggttga accagctcca cctccgacac taccaggtcc tccaccattg
     3361 aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt attggctaat caaagtaggt
     3421 gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga atttttgcca agcgttggca
     3481 ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag attgcaagat acccaaagtc
     3541 aaaacgtaga tgtatgggaa tccgagccaa ccttgcatca taatcaaggc aatcttagtc
     3601 caagttgggt ctgttttcca aggaataaga gctccatcaa ggaaaggaag gaatttagcc
     3661 aagattggca atacttgagt gttgatagca ccgacactat cgttaaacat gtttgagaat
     3721 gtcaagatag tgatgaaggc tgggacagcc caaggaagaa ggaaaataac accaaagata
     3781 cgttttcctt tgataaatgg ttggttggca atgatagctg tgaagatacc aattacgatt
     3841 tgtaaagtag aagctgccaa agcccaaatg atagtccaag aaagaacaga accaaaggca
     3901 gaacggaagg tactcaagct ccaaatgttt gtaaagttgg tcaaaccaac ccagtccaac
     3961 aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa aggcgatcat caaggttacg
     4021 ataactggga agataatcgc gaaggtcatg gcaacataag atggaatgat caagaggtaa
     4081 gggaagccat tttcataaat ccctttgatc atgtctttga gtgtgcgtgg aactggaatt
     4141 ccattgttaa tgcgttttgc aatcgtatgt gcatctttga tatttgagaa ataaaagagt
     4201 acataaacga ttacaaagat tagatggaag gcaccacgaa tcagcataaa gagggaatta
     4261 tcacgacctg gtttgtcacc aagagtgatg aggttgctca attcaggggt tgcaagtgct
     4321 aggaagtaaa ggacaaatac gatggttaca ccaaggaaga taaaaccttt ggctttttgt
     4381 ttattgtaaa tctgtcctaa cccaggaatg atagacagca gggctgcttt actaggttgt
     4441 tgcttttcca tattaactcc tttcatagga tactactttt ttataagaaa gctaaattat
     4501 ttgtgtctct attgataaat tcaaaggggg atttgatttc cacccccctt gaacaaattt
     4561 tttattcacc aaatttttgt ttgattgttt ctttgatcaa tgttacagca tcgttagcag
     4621 ctgttttagc atctttttga ccacttacag catcaaagag catatttttc gctggatccc
     4681 aaactgcaga catttgagag atgtttggca gtggttgagt gttcttgaac tgtttgataa
     4741 cagctgttgt caactcatcg tttttacctt cagcgtatga acgagcctca gtattagctg
     4801 ggatttcgtt agtcttatca tataatactt tttgttgttc agttgcaaca aggaagtcta
     4861 caaatttttg agaagcttca aggttcttaa cggcttgagg aatgacccaa gctttaccac
     4921 caccgaatgc agcatattct tttccatttg gaagagttgg gatagttgca actccgtagt
     4981 ttactttagc atctttaaag gcttgagctt tccaaggtcc gtcgatgata gcagctgttt
     5041 taccttcttg gaattgagtt tggattaagt ttccagcacc ttctgtatct tgcatacctt
     5101 taggccattt ttcgtaccaa gatttagcgt agttgatacc tgcgatagaa ccgtcgtttg
     5161 caagaccgat gtctttagcg tctttaccgt tttggccaaa gacgtaagca ccgttaccgg
     5221 caagaagtcc atatgtatag tagaagtttg tccagtcagc taggaaggca gtagttttac
     5281 catcttcacc agcgaatgcg tatttgctat ctttagcaag gttttccaag tcagcaaatg
     5341 tttttggagc atctttcacc aagtctttgt tgtagtacat aacaagtgac tcgataacgg
     5401 caggagcacc gtaaacttta ccattagcag ctgttacaag agatttagtt gtgtcgtctg
     5461 ttttagcacc atcgctcaat ttcacttctg aaagttgtcc gtcagaacca aggctaccta
     5521 cacggtcgta tggagccatc ataacatcag ggacattacc agattggttg tcaagagaaa
     5581 gtttatcaag acctcctaga gcatcaccag ttttaagagt gacttttact ccagcttctt
     5641 tttcataagc tttagcaacc tcttcaatat agctcttata tccctcgtct acatatacag
     5701 tgagttcttt gacttcagat gaaccagaat cagcaggctt atcagcagtt ttgcttccgc
     5761 aagctaccaa aagcaagcta gcaagtgtag cagttccaag caccgcagtg ctcttcataa
     5821 atttagatga catagtgtat tcctcctaaa gaatagcaag ttttattgat aaggaaacgc
     5881 aaacgttttc ctttatgagc ttagtatagc acaaatagaa aacggttgca agtatttttt
     5941 gtaaaaattt taaaaaattt ttaagcttga tttgatagta taattttgca ttttaataga
     6001 agaaaagtat gaaatagata agaatacagt atttttaata aaaatatatg gaatctgtct
     6061 aaagagggaa atcaggaggg gtacctccct gtttctaatc tatatctatt ttctatagac
     6121 gtttgtgctt tgttgcatat aaattcaagc tccctaagga ggttttgtac tttgtatact
     6181 gtctcgtgag agtcaaactt taggattaga tagttttaag ttatctttgc taaaatgagt
     6241 tagtctcctt aaaaataatc aaaaaagttt tttaaaaacg cttgcaatta tgcttgaaaa
     6301 ggagtatact tataagtaac gcaaacgttt gcgtctgaaa aatacgcaac gttccattat
     6361 tttaacacac gaggtgctat tatgaaaaaa cgtcaaagtg gtgtgttgat gcacatctct
     6421 tctcttccag gagcttacgg aatcggatca tttggtcaaa gtgcttacga cttcgttgat
     6481 ttcttggtcc gtacaaaaca acgttactgg caaatccttc cattaggagc aactagttac
     6541 ggggattctc cttaccaatc tttctcagcc ttcgcaggaa acactcattt tatcgattta
     6601 gatatcttgg tggagcaagg tttgttggaa gcaagtgacc ttgaaggagt tgactttggt
     6661 agcgatgcgt ctgaagttga ctatgctaaa atctactatg cacgtcgtcc tcttttagaa
     6721 aaagcggtga aacgtttctt tgaagtcgga gatgttaaag attttgagaa atttgctcaa
     6781 gacaaccaat catggcttga gctctttgct gagtatatgg ctatcaaaga gtattttgac
     6841 aatcttgctt ggactgaatg gccagatgca gatgctcgtg ctcgtaaagc ttcagcactt
     6901 gaaagctatc gtgagcaatt ggcagacaag ttggtttacc accgtgtgac tcaatacttc
     6961 ttcttccaac aatggttgaa attgaaagct tacgctaacg acaaccacat cgaaatcgtt
     7021 ggggacatgc caatctacgt agcggaagat tcaagtgata tgtgggcaaa tccacatctc
     7081 ttcaaaacag atgtcaatgg taaggctact tgtatcgcag gatgcccacc agatgagttt
     7141 tctgtaactg gtcagctttg gggtaatcca atctatgact gggaagcaat ggacaaagac
     7201 ggctacaaat ggtggattga acgcttgcgt gaaagcttca aaatctacga tatcgttcgt
     7261 atcgaccact tccgtggctt cgaatcttac tgggaaatcc ctgctggttc cgatacagca
     7321 gcacctggtg agtgggtgaa aggtccaggc tacaagcttt ttgcagccgt taaggaagaa
     7381 cttggtgagc taaacatcat cgcagaagac cttggcttca tgacagatga agtgatcgaa
     7441 ttgcgtgaac gtactggctt cccaggaatg aagattcttc aatttgcctt caacccagaa
     7501 gacgaaagca ttgatagccc acacttggca cctgctaact cagttatgta cacaggaaca
     7561 cacgataaca atacggttct tggttggtac cgtaatgaga ttgatgatgc gactcgtgag
     7621 tacatggctc gttacacgaa ccgtaaagaa tacgaaacag tggtacacgc tatgcttcgt
     7681 acagtatttt catcagttag ctttatggca attgcaacta tgcaagattt actagaattg
     7741 gatgaggcag ctcgtatgaa cttcccatct acccttggtg gaaactggtc ttggcgtatg
     7801 actgaagatc aattgacacc agctgtcgag gaaggtttgc ttgacttgac aacaatttat
     7861 cgccgaatta atgaaaattt ggtagattta aagaaataag acaataatca ggagacaact
     7921 aaacatgtta tcactacaag aatttgtaca aaatcgttac aataaaacca ttgcagaatg
     7981 tagcaatgaa gagctttacc ttgctcttct taactacagc aagcttgcaa gcagccaaaa
     8041 accagtcaac actggtaaga aaaaagttta ctacatctca gctgagttct tgattggtaa
     8101 actcttgtca aacaacttga ttaaccttgg tctttacgac gatgttaaaa aagaacttgc
     8161 agctgcaggt aaagacttga tcgaagttga agaagttgaa ttggaaccat ctcttggtaa
     8221 tggtggtttg ggacgtttgg ctgcctgctt tatcgactca attgctactc ttggtttgaa
     8281 tggtgacggt gttggtctta actaccactt tggtcttttc caacaagttc ttaaaaacaa
     8341 ccaacaagaa acaattccaa atgcatggtt gacagagcaa aactggttgg ttcgctcaag
     8401 ccgtagctac aaagtaccat ttgcagactt tactttgaca tcaactcttt acgatattga
     8461 tgttactggt tatgaaacag cgactaaaaa ccgcttgcgt ttgtttgact tggattcagt
     8521 tgattcttct attattaaag atggtatcaa ctttgacaag acagatatcg ctcgcaactt
     8581 gactctcttc ctttacccag atgatagtga ccgtcaaggt gaattgctcc gtatcttcca
     8641 acaatacttc atggtttcaa acggtgcgca attgatcatc gacgaagcaa tcgaaaaagg
     8701 aagcaacttg catgaccttg ctgactacgc agttgtccaa atcaacgata ctcacccatc
     8761 aatggtgatt cctgaattga ttcgtctttt gactgcacgt ggtatcgatc ttgacgaagc
     8821 aatttcaatt gttcgtagca tgactgccta cactaaccac acaatccttg ctgaagcgct
     8881 tgaaaaatgg cctcttgaat tcttgcaaga agtggttcct cacttggtac caatcatcga
     8941 agaattggac cgtcgtgtga aggcagagta caaagatcca gctgttcaaa tcatcgatga
     9001 gagcggacgt gttcacatgg ctcacatgga tatccactac ggatacagtg ttaacggggt
     9061 tgcagcactc catactgaaa tcttgaaaaa ttctgagttg aaagccttct acgaccttta
     9121 cccagaaaag ttcaacaaca aaacaaacgg tatcactttc cgtcgttggc ttatgcatgc
     9181 taacccaaga ttgtctcact acttggatga gattcttgga gatggttggc accatgaagc
     9241 agatgagctt gaaaaacttt tgtcttatga agacaaagca gctgtcaaag aaaaattgga
     9301 aagcatcaag gctcacaaca aacgtaaatt ggctcgtcac ttgaaagaac accaaggtgt
     9361 ggaaatcaat tcaaattcta tctttgatat ccaaatcaaa cgtcttcacg agtacaaacg
     9421 ccaacaaatg aacgctttgt acgtaatcca caaatacctt gacatcaaag ctggtaacat
     9481 ccctgctcgc ccaattacaa tcttctttgg tggtaaagca gctccagcct acacaatcgc
     9541 tcaagatatc attcacttga tcctttgcat gtcagaagtt attgctaacg atccagcagt
     9601 agctccacac ttgcaagtag ttatggttga aaactacaac gttactgcag caagcttcct
     9661 tatcccagca tgtgatatct cagaacaaat ctcacttgct tctaaagaag cttcaggtac
     9721 tggtaacatg aaattcatgt tgaacggagc tttgacactt ggtactatgg acggtgctaa
     9781 cgtggaaatc gctgagttgg ttggagaaga aaacatctac atcttcggtg aagattcaga
     9841 aactgttatc gacctttacg caaaagcagc ttacaaatca agcgaattct acgctcgtga
     9901 agctatcaaa ccattggttg acttcatcgt tagtgatgca gttcttgcag ctggaaacaa
     9961 agagcgcttg gaacgtcttt acaatgaatt gatcaacaaa gactggttca tgactcttct
    10021 tgacttggaa gactacatca aagtcaaaga gcaaatgctt gctgactacg aagaccgtga
    10081 cgcatggttg gataaagtca tcgttaacat ttctaaagca ggattcttct catctgaccg
    10141 tacaatcgct cagtataatg aagacatctg gcacttgaac taatactctt cgaaaatctc
    10201 ttcaaaccac gtcagcttta tctgcaacct caaagcggtg ctttgagcaa cctgcggcta
    10261 gcttcctagt ttgctctttg attttcattg agtataagat gcaaatttat actaatacat
    10321 tttgtaaaaa agcgagtttc gattgaaatt cgctttttta aatgctgtgg atttgggtca
    10381 atcttgtcta aaaataggga aatcctagat acagtgaagg ctttaaatgc tggtttttac
    10441 tgtcttcagc cttatatttt ttcgtagttg gttacctcat atctcttgta ttcgcttaca
    10501 taaagtatta taatataatt gtaggaaaga aggtgttttt atgatataca cacttaaatt
    10561 ggtgttgttt attacctttc ttgtaataag cttgttacct gataagattt ttggaaaaaa
    10621 taaaaaaatt tggaaaatag tttttgcaat attgacggca gtggcagcat ttatatttat
    10681 gtactaagtt attttaagaa tgtagggaaa taaaccctac attcttttta gttttttctg
    10741 ttttctaaat tctatttatc caagcgcttc aacatttctt gcttcttcgc ttcaagttct
    10801 gcacgctttt cttcgatttc ggcatgtttt ttctcgagtt cagaacaact tgcaccattg
    10861 ctaaattctt ttcgccatca ggagataggg tgagtcgaca tgtctattac tcacccaaag
    10921 cagtcctaca aagcaggaat tttctgttac ttttttggaa atagtaacgt ttatacagct
    10981 ttgacacttc gtatcaaagc gccaaacaca ctccgaggga tttacagaaa gcagaaaagg
    11041 aatgatctgg tataagatca ttccttttct ctctttttct ttaagtaatt atatacaatg
    11101 tacgacgaag tcgtcattgc aatgctgatc caccacctaa agggaacttt aaacaacatt
    11161 gataagataa agaatataaa caacgaaaat acgttatacc caattaattt tattgtatat
    11221 ctcatgatta aaagttaatc cttccgttgt taggaatggc atcattttta tcccataatt
    11281 gtgttaaata agtccccggt gataataaat tcatagcgga ttctaaagca acatcattta
    11341 caaaccaact acctagatat ctagaaattg ctgaacgaat agcacttttt gctgcatgtt
    11401 ttccttttac tttaattaga tttgcaaggc ctgcagtagt tcctcctaat gctaaagcta
    11461 ttgcagtatc taatagagca cccatttgat taactgtaat accttgccaa gctgctctaa
    11521 atggagagta tgtaggtggg attgtataat cgccttgtaa ttgtcggtta attacttctt
    11581 tgatccattg ttgtgagacg tctggatgaa aagattggat ttcgtttgca agtgtattga
    11641 tttgttcttc tgttagagaa gtgacaggtt gaagttccat atttgtttca atttgtgata
    11701 cttgttcaga agcgtataca gctgaaacac ttggaatcgc tgatacaatt aacacaattg
    11761 acgtcaaaaa aaccgaaata aatttcatta atttgttcat gagcttttct cctttttatt
    11821 tgtatttgct tacattttat tatatactgt tattatagtc aagaaaaata tgctattatg
    11881 ttaaaaaaat atttttcaaa atataaatgg acggatttat tttggattct ttttgtaatt
    11941 ggggcatgcc tcttgacggg taatagtagt cttttccccc ttacccatca agaattctct
    12001 tttcgtggta gcgtttgggg tctggtactg gccttatatc acttattgtt cattgataag
    12061 tttgtaattt cgaatcgaaa ataaaaatta gaactatgat tgactggcta cttttaatat
    12121 tgattttgga ggaagatttt gtctctatta tttattattt taaatttatc tattttgtac
    12181 aagatttatt ctttgagacg ggagaagtcg aaatacttga tttatacggc ctatatcata
    12241 tttggggtaa atgtagtata tggtattcaa tggttattaa aagaactgat ttcaactatt
    12301 tccacttaat atgtatgaaa actataacaa aacgcataag attaaggttt ttaagcacct
    12361 gttcttatac gtttttgtaa tattgaagat tttcggtaag ttttctactt ttgcgaagtc
    12421 tagtttagaa tgctttccca accaaaatct ctgcttcgat ggtaatctct gtcagttggc
    12481 tccagtcaat cttgctctgg tcaacgtgaa agaggagagg agtcatactg agtagggctt
    12541 ggagttgttc tgctgtgata gtcttagtca gagaggcagt ttgactagat aggatggtaa
    12601 agtgttcctg gaaatgctcc ttgatatctt ggttagaata ctccttgttt gtcagctggt
    12661 cctgtactct ttgacggatt tctttgaggt gattttcagt tgggataacc tttatcaaga
    12721 taccgtcttt ggataaaacg cgacgaaatt ctccatagtt ggcaggtgag aagatatcaa
    12781 gcagaatatc catgttagcg tcttttatag gaagtcgtgc caagtcgcca acgaaccaat
    12841 tgactgccca gttgggttca cttttagcag cgatttggac tgaatctttg gagatgtcaa
    12901 aggcatagaa agttttttca gagtgacttt cttgtagttt gcgagaatag aatccttcac
    12961 cacaaccgat atccaaaatt gttgtggtag tttttgagct tgcaagcaag tcagatacag
    13021 catctaagat agcttggtaa aagccggctt ctaggatttg ttgacggttt tgaaaatttt
    13081 ccttgtcata gttagcagat tgcttgattt gaggtgctag attgacatag ccaaatttcg
    13141 ccaagtcaaa agaatgacgg ttgcagcact tgaaattagt ctctaacaga gtcagatttt
    13201 cttgacagat aggacaggca aaggcagtcg cagaagcaaa acgctgaagt ttgggcttga
    13261 gatttgtatt catagtttaa gtgtatcaaa agaggcaaat gaaagcaact ttaggaataa
    13321 gtagatggga gattcagtag aaataaaact aattctccaa tttatagaat gaaattgctt
    13381 ttatatctaa attgctatat aataatgata aggaggaaat aagtatgtta aaagaagtat
    13441 taaccgttgc aaaagttgcg aaaaaatctt cattattttt gggtggtgtc gcatttggta
    13501 cccttggttt gaaaatctta gcaagtaagg aagctaaaaa aggttattct aaagctttgg
    13561 ctaaggctta caagttgaaa gacgagctag atgcatctgt ttctgttgtg aagcaacatg
    13621 gagacgatgt cttgcaagat gccaaatatt tgtacgagca agagaaaaaa gaagagcaat
    13681 tagatagcct tataggtgaa taatatgtct tttaaagtgc tacatagagg ataccaacat
    13741 atccgactat catcttcttt ttcacttacc ttggatattc aagactatct tcgttccttg
    13801 gcgagagatg aaaaggggat tgagtctatc cagttttaca tggatcaaca gcactttact
    13861 ctacgcataa aagaaggctt ttctgtatta gataatgcag aagccttttt aaaaagaatt
    13921 gataaaggga aagtttctga gttgatgact cttcccattc gtagagaaga gagtgcttat
    13981 tctattgttt caggtgcagc ggttaagcgt gtactttttc gtagttttgt gccgtatcct
    14041 attcgctata tatggacttg ttatcaggct ttgggttata ttagagaagc ctatcaaaca
    14101 ctagcgcgta aggaactaac gatggaagtc ttggactgtt cggctatttt attgtccttg
    14161 tttatgaacc aatccaagac agctagcaat atcatgttta tgcttgattt ggggaatcat
    14221 ttagatcagt ggtccttgaa aaaaactgca acagatttag aacagagtct tcttgcaaaa
    14281 gagagcgatg tattcctagt acagggcgat acggttgtta gtataaagag ttccgatgtt
    14341 caaataggag atgtcttgat cttatctcaa ggaaatgaaa ttctgtttga tgggcaagta
    14401 gtttcaggtt taggtatggt caacgaaagt tccttgacag gagagagttt tccagttgaa
    14461 aaaagagagt ctgatttggt ttgtgcaaat acagtattag aaactggaga gttacgcatt
    14521 cgtgtaacag ataatcagat gaacagccgt attttacagc tgattgagtt gatgaagaaa
    14581 tctgaagaaa acaagaaaac gaaacaacgc tatttcatca agatggcgga taaagtcgtc
    14641 aaatataatt tcttgggggc tgggctgact tacctattga caggttcttt ttctaaggct
    14701 atttctttcc tattggtcga tttctcctgc gctttgaaaa tctctactcc tgtagcttat
    14761 ttgacagtta tcaaggaggg gttgaaccgt gaaatggtga ttaaggatgg agatgttctg
    14821 gagaaatatc tggaagttga tactttcttg tttgataaga caggaacaat cacaactagt
    14881 tatcctatag ttgaaaaggt gttacctttt ggagactata gtgaggaaga tattctcaga
    14941 atcagtgcct gtcttgagga acacatttat catcctattg ctaatgccat cgtcaagcaa
    15001 gctgagatag agggaattga acatgaggaa atgcatggga aactccaata tatcgcaagc
    15061 aaggggatca aatctcatat agatggccaa ccagttctta ttgggaatta tgtcttgatg
    15121 caggatgagc agattcatat cagttcagaa caaaatgctt taattgaaga gtacaagagt
    15181 cactacaatc tcttattctt ggcttatcaa aatgaattga ttggaatgtt ctgcattcat
    15241 actcctttga gaaaagaagc aaaaacagcc ttggataaac ttaaggcaca ggggaaaaaa
    15301 ttgattctgg caacaggaga caccttgatt aggacagagg aattagtcaa agatttgccc
    15361 tttgatcagg tctatacaga cttgaaacct gatgggaaat ttgagttagt agagaaactg
    15421 cagaaagcag gtcacactat tttgatggtt ggagatggct tgaatgactc agcggcttta
    15481 actctatcag atatcggtgt ggtgatgaat gagagtgcag atatttctaa gcagatgagt
    15541 gatatcttat tgttagataa tcgtttggat ttcttccaag agttggattc gttatcatca
    15601 tctttgcaaa cactcatcaa gaaaaatatt caggataccg ttgtcgtaaa tagtagtttg
    15661 attggctttg gcttatttaa ttggttcagt ccttcaaatc tctctatctt acataatcta
    15721 acaaccttgc gcattgtcct gcgtagcctg tctattaaaa atagatagat gagagttatt
    15781 aacagcaaaa aggagttacc tttctcgagg ttaactcctt tgtttataga taaatgttga
    15841 atagtttagt aagtcaatac aaagtatttt ttcttcccac gacggataac agtcagttca
    15901 ttttctaact tatcagcgtc actcaagaca tagtcaaggt cttggatgcg gtcgccgttt
    15961 acgtagatgg ctccgttttg gacgtcttca cgggcttggc gttttgagtt aactatacca
    16021 gatgagacga gcagttccac gatattgttg ttttcgtctg cctgtacttg gtagtttggc
    16081 acaccacgaa gtccttgttt gagctctttg acagaaaggt ttttgatgtt tcctgcaaag
    16141 agttgctcag tgatgttaag tgcttctttg taggcttctt ctccgtgaac aagtgtaaca
    16201 acttcacgag ccaagacttt ttgagccaag cgttcgtgtg gcgctgcttc aaattgttta
    16261 cgaatatctt caatctcatc aagtgacaag aaagtaaaga ttttcaagaa gcgaacagcg
    16321 tcagcgtcca tcacgttcat ccagaattgg tacatttcgt atggagaagt cttttcggga
    16381 ttgagccaga cggcatttcc ttctgattta ccaaatttct taccagttgc atctgtgatt
    16441 agtggaacag tgataacgtg accagtcttg tccgccttac gacgaagcaa ttcggtacca
    16501 gctgtcatat ttccccactg gtcagaacca ccgatttgaa gagtgacatt atggtcttgg
    16561 ttaaggacga agaagtcgta cccttgcatg atttggtaag cgaactcagt gtaagaaatt
    16621 cctgtttcga tccgtttttt aacagattcc ttactcatca tgtagttgac cgtgaagtat
    16681 tttccaatat cacggaggaa gtcaatgaag ctgatgctgc caaaccagtc gtagttgttg
    16741 accatgacag ccttgttttc gccattttca aagtcaagaa aacgagaaag ttgtccttgg
    16801 atagacttga cccagccatc tactgtgtct tttgtttgga gactacgttc agcatctttg
    16861 aaggacggat ctccgatgag acctgtagca ccgccaacga gcgcataagg tttgtgacct
    16921 gctagttgca agcgacgact tgtcaagatt gcgacaaggt ggcctaggtg aaggctgtca
    16981 gcagttggat cgtagccagt atagtaagaa acttgacctt cttctagggc tttacgcaaa
    17041 gcttcttcat cagtcgtttg aaatatcaaa ccacgctctt ttagctcatc aaaaatgtgc
    17101 atgtgtcttt tctccttttt aaaattattg tttctaccta ttgtatcaca aacttgggca
    17161 atagcctagc agaataggga agaaagtggc tattttattg aaaatttccc ttttgtggta
    17221 taatagataa agtgaggaaa tccatgcaaa atcaattaaa tgaattaaaa cgaaaaatgc
    17281 tggaattttt ccagcaaaaa caaaaaaata aaaaatcagc tagacctggc aagaaaggtt
    17341 caagtaccaa aaaatctaaa accttagata agtcagccat tttcccagct attttactga
    17401 gtataaaagc cttatttaac ttactctttg tactctgttt tctaggagga atgttgggag
    17461 ttgggattgc tttggggtac ggagtggcct tatttgacaa ggttcgggtg cctcagacag
    17521 aagaattggt gaatcaggtc aaggacatct cttctatttc agagattacc tattcggacg
    17581 ggacggtgat tgcttccata gagagtgatt tgttgcgcac ttctatctca tctgagcaaa
    17641 tttcggaaaa tctgaagaag gctatcattg cgacagaaga tgaacacttt aaagaacata
    17701 agggtgtagt acccaaggcg gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt
    17761 cctctagtgg gggttcaacc ttgacccagc aactaattaa acagcaggtg gttggggatg
    17821 cgccgacctt ggctcgtaag gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca
    17881 tgaataaaga tgagatttta acgacctatc tcaatgtggc tccctttggc cgaaataata
    17941 agggacagaa tattgcaggg gctcggcaag cagctgaggg aattttcggt gtagatgcca
    18001 gtcagttgac tgttcctcaa gcagcatttt tagcaggact tccacagagt cccattactt
    18061 actctcctta tgaaaatact ggggagttga agagtgatga agacctagaa attggcttaa
    18121 gacgggctaa ggcagttctt tacagtatgt atcgtacagg tgcattaagc aaagacgagt
    18181 attctcagta caaggattat gaccttaaac aggacttttt accatcgggc acggttacag
    18241 gaatttcacg agactattta tactttacaa ctttggcaga agctcaagaa cgtatgtatg
    18301 actatctagc tcagagagac aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga
    18361 agttttatcg agatttggca gccaaggaaa ttgaaaatgg tggttataag attactacta
    18421 ccatagatca gaaaattcat tctgccatgc aaagtgcggt tgctgattat ggctatcttt
    18481 tagacgatgg aacaggtcgt gtagaagtag ggaatgtctt gatggacaac caaacaggtg
    18541 ctattctagg ctttgtaggt ggtcgtaatt atcaagaaaa tcaaaataat catgcctttg
    18601 ataccaaacg ttcgccagct tctactacca agcccttgct ggcctacggt attgctattg
    18661 accagggctt gatgggaagt gaaacgattc tatctaacta tccaacaaac tttgctaatg
    18721 gcaatccgat tatgtatgct aatagcaagg gaacaggaat gatgaccttg ggagaagctc
    18781 tgaactattc atggaatatc cctgcttact ggacctatcg tatgctccgt gaaaagggtg
    18841 ttgatgtcaa gggttatatg gaaaagatgg gttacgagat tcctgagtac ggtattgaga
    18901 gcttgccaat gggtggtggt attgaagtca cagttgccca gcataccaat ggctatcaga
    18961 ccttagctaa taatggagtt tatcatcaga agcatgtgat ttcaaagatt gaagcagcag
    19021 atggtagagt ggtgtatgag tatcaggata aaccggttca agtctattca aaagctactg
    19081 cgacgattat gcagggattg ctacgagaag ttctatcttc tcgtgtgaca acaaccttca
    19141 agtctaacct gacttcttta aatcctactc tggctactgc agattggatt gggaagactg
    19201 gtacaaccaa ccaagacgaa aatatgtggc tcatgctttc gacacctaga ttaaccctag
    19261 gtggctggat tgggcatgat gataatcatt cattgtcacg tagagcaggt tattctaata
    19321 actctaatta catggctcat ctggtaaatg cgattcagca agcttcccca agcatttggg
    19381 ggaacgagcg ctttgcttta gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag
    19441 gtcaaaaacc agggaaggtt tctgttgaag gaaaagaagt agaggtcaca ggttcgactg
    19501 ttaccagcta ttgggctaat aagtcaggag cgccagcgac aagttatcgc tttgctattg
    19561 gcggaagtga tgcggattat cagaatgctt ggtctagtat tgtggggagt ctaccaactc
    19621 catccagctc cagcagttca agtagtagtt ctagcgatag cagtaactca agtactacac
    19681 gaccttcttc ttcaagggcg agacgataat tctctaaatg aagtggccaa tcaatggatt
    19741 gccacttttt tcttttcgtg ttacaataag ggtatgaatc agtatcagaa aaagattgtt
    19801 aacggaaaaa tttattcgct cctatccggc ttaatatggg gaatctgtgg aattttagga
    19861 gagtacttct ttactcatta tcaggtgtct tcgggctgga ttacctctat gcgtttgaca
    19921 ctggcaggga gtcttgtact catttggtct gcaatacaat taaaatcgca agtgctagat
    19981 atttggcgag acaagaaaaa ttacctgccc tttttagcct atgctatttt ggggattttt
    20041 tcagttcagt attttttcta tctctgtgta gaatactcaa atgctacgac agcaactatt
    20101 ttacagttta ttagccctgt ctttatcctc ttttacaatc gcttggttta tcaaaaacga
    20161 gcgtcaaaaa gcgctgtttt ctatgttttg gttgccatgc tgggtgtttg cttgatggcg
    20221 acaaagggag acctctctca gttatccatg acgccgctag ctcttataac aggtttgctg
    20281 agtgccatgg gtgttatgtt taatgttatc ttgccccaac cttttgctaa gcgttatggt
    20341 tttgttccta cggttgggtg ggggatgatt ttggcaggtt tgtttagcaa tgtcctctcg
    20401 ccggtttatc agctttcctt tactcttgat atttggagta tcttgatttg cctcattatc
    20461 gctttctttg gaacggcttt tgcttttttc atttccatga aggctgtgtc cttggtttct
    20521 cctttggtgg ttgccgttat cagtgccagt gaacctctct cttctgctct cttgagtgtt
    20581 ttgttcttag gattagtagt ggattggtcc ctccttctag ctatagcctt gattatttta
    20641 cccatgatat ttttgtctat agaagaagcg aaagaaagta gataaaaagt cttttcttaa
    20701 ttctaaaagt gtgctatact ggaatagtca ataaaacacg gggagatagt tgtgaagagt
    20761 gtttttaggt tgtatcggta ggggcttgct tttaccgaca gcacgtttta tctcacatcc
    20821 ctaaaaaatc atacctaaaa acagacaaaa aggtttcaaa tttgaggcct tttttggtag
    20881 aataggtatc attataacga accaggaggc acctatgact gctacaaaaa tgaacgctca
    20941 agaaattatc caatttatcg ccaatgctga aaagaaaacc agtgtcaaag taacctttga
    21001 ggggcaactc gcaactgctg tgcctagctc tgttgtcaaa ctaggaaatg tcctattcgg
    21061 agactggaag gacgtggctc cgcttcttga aggtttggta gaaaatcaag attatgttgt
    21121 cgagcaagat gctcgtaatt ctgcagttcc tttgctagat aagcgtgcta tcaacgctcg
    21181 tatcgagcca ggtgctatta tccgtgacca ggtggaaatt ggtgacaatg ctgttatcat
    21241 gatgggagct gttatcaata tcggtgctga aatcggtgct ggaaccatga ttgacatggg
    21301 tgccatcctt ggtggccgtg ccattgttgg aaaaaatagc cacgttggtg caggtgcagt
    21361 tttggcaggt gtgattgagc cagctagtgc tgaaccagtc cgtgtcggag acaatgttct
    21421 catcggggct aatgcagtgg ttatcgaagg agtccaaatc ggtagtggtt cagttgtcgc
    21481 agcaggagct attgttaccc aagatgtccc agaaaacgtg gtagtagcag gtgttccagc
    21541 tcgtattatc aaagaaattg atgcccaaac tcaacaaaaa acagcgctag aggatgcgct
    21601 tcgtaccttg taattgtaaa agtaaaaaag aggcggaacc ctttttccag cctctttctg
    21661 ctatatcgga ggacagatag atgttagatt tgattcagac tagacgagat ttacaccaga
    21721 ttccagagat tggcttggag gagttcaaga ctcaggctta tttgctggat gtgattgaga
    21781 aattgactac gggcaaggat tttgttcaaa ttcgtacttg gcggacaggg attttggtct
    21841 acctgcaggg aagtcagccg gagcgaacca ttggttggcg gacagatatt gatggcctgc
    21901 ctatcgtcga acaaacaggt ctaccttttg cttctcaaca ccaaggtcgc atgcatgcct
    21961 gtggtcatga ttttcatatg accattgcct taggctgtct tgagcgcgcc cttgaggagc
    22021 aacccaagaa taatctgctc tttctatttc agcctgctga agaaaatgaa gctggtggta
    22081 tgctcatgta tgaggacgat gcttttggag attggttgcc agatcaattc tatggtctcc
    22141 atgttcgtcc agatttgaaa gtcggccaga ttgcgactaa tactcataca ctctttgcag
    22201 gaacttgcga ggtgaagatc cgtttcaaag gcaaaggtgg ccacgcagct tttcctcatg
    22261 aagccaatga cgccttggtg gcggctagtt actttgtgac ccaagtgcag tcagttgtta
    22321 gccgcaatgt caacccaatc gagggagcag tggtgacctt cggcgttttt caagctggaa
    22381 ccaccaacaa tgtcatcaca gacacagctt ttttacatgg aactattcgt gccttgacac
    22441 aggacatgag tctcttggtg caaaagaggg taaaaacagt tgcagaaggg gttgcagctg
    22501 cctttgatat ggaagtcgaa gtggaactca aacaaggtgg atacctacct gttgagaaca
    22561 atccagcctt ggcgcgtgaa ctgatggact tctttgacga gaaagacgga atcgagttga
    22621 ttgatatcga acctgctatg acaggcgagg actttggtta tctcctttca aaggttgatg
    22681 gcgtgatgtt ttggctaggt atcgatagtc cctacgctct tcatcaccct caaatgagtc
    22741 ctaaggaaga agtcttagct attggggtgg ctgcggtgtc tagtttcctg aaaaagaagg
    22801 cagcagaata gagggcttgt ctatgaaatc ggaattacgc aagcaagtct tgcatgaaat
    22861 gaaggctata tctcaagagc aaaaacaggc tatagaccaa gctttaaccg agcggctttt
    22921 acaccatccc ttctaccaag aagccaaggt catcgcaacc tacctctctt tttctcatga
    22981 gtttcaaacg cgggaactga ttgagcaggc gctgaaggac ggcaagaagg ttttaatacc
    23041 caaaacttat cccaaggggc gcatggagtt tgtggcctat gatccgcaac agttggtaaa
    23101 aacttccttt gccttactgg agccacaggg agatgtggaa gtggtggatg catctcagat
    23161 tgatttgatt catgttcctg gtctggcttt tacgacgaaa ggatatcgga taggatacgg
    23221 tggaggctat tatgaccgct atctggaaca tttttctggt cgtactttga gtacgatata
    23281 tccttgtcaa attcaggact ttatacctga aaaccatgat attcctgttc aggaggtatt
    23341 aattgatgaa ggaaatcttt gatagacgtt accctgtgac gagtttcttc ctcttagtga
    23401 cggccttggt atttttacta atgttggtca ctgcaggcgg aaactttgac agggcagata
    23461 cattatttcg atttggagcc atgtatgggc cagctattcg cctctttccc gagcaggttt
    23521 ggcgtctctt gtctgccatt tttgttcata ttgggtggga acatttcatt gttaatatgc
    23581 tttcacttta ttatcttgga aggcaggtag aggagatttt cggttctaag cagtttttct
    23641 ttctctatct tttatcagga atgatgggca atctctttgt ttttgtattt agtcctaaat
    23701 ccttagcagc aggcgcctct acctctcttt atgggctatt tgccgcgatt attgttcttc
    23761 gctatgcaac tcgcaatcct tatatccaac agctagggca atcctatctg acactttttg
    23821 tggttaacat tattggaagt gttctgattc caggaatcag cctagcaggc catatcggtg
    23881 gtgcagttgg tggcgcattt ctagcagtta tctttccagt tagaggagaa aaacggatgt
    23941 ataacaccag ccagagatta ggagcggtag tcttgttcgt aggactcgcc attttgcttt
    24001 tctacaaggg aatgggaatg tgacgaagtt gaaagaaaat ttgtgtaatg aaaaaagata
    24061 aggcattttt tgaaccttat ctttttattt tattccttct cagtcaattc ttttccaagt
    24121 tggatgaggt aattcttcaa atcatctttg acttgtggat gtttgagggc gtagtcaata
    24181 gatgttttca taaagccaaa cttatcccca acgtcgtaac gagctcctgt aaattcacgg
    24241 gcaaaaacac gctgtgtttt attaagagta tcgattgcat cagtaagttg gatttcattt
    24301 ccagcaccag gagcttggtt ttcgaggatt tggaaaattt caggcgtgag gaggtagcgt
    24361 ccgataatag caaggtcgct aggagcgtcc tctggagctg gtttttcaac aaaggtttca
    24421 acactgtaaa gaccatcttt tccttcgcct tgcggagcaa taaccccgta agcagatact
    24481 tcgtcatgag ggactggcat gacagcgata gtagacgcgt gggtacgctt gtagtcatcc
    24541 atgagttgtt tggtaagtgg aacagccttt tcgtctgtga tatccatcaa gtcatcacca
    24601 agcataacga caaaaggttc atttccgacg aaagccttgg cttgcaaaac agcatctccg
    24661 agaccgcgtg gatgagtttg gcggataaaa tgcagacgca tgccagttgt ttcatcaact
    24721 agcttcaaaa gatctgtttt ccctttttct ttgaggttat attccaattc gaagtttgaa
    24781 tcgaagtggt cctcaataga acgttttgat ttaccagtga caactagaat atcttcaata
    24841 cctgatttga gagcctcttc cacgataaac tggatagttg gtttgtctac gattggcaac
    24901 atttctttgg caagggcctt ggttgctggt aaaaatcgag ttcctagtcc agcagcaggg
    24961 ataactgcct ttctaacttt tgatgtcata aaaatccttt ctatagaggg ttaagaccac
    25021 tcattttctg ctttaaattc attgttcatg atgtcataaa tggcatcttt gatattggtt
    25081 ccgtgataaa taacttggta aatagcctgt gtaatgggca tatagactcc aagttcttgg
    25141 gctagttcat aggctgctcg agtcgttgaa attccttcga ttaccatgcc catattagct
    25201 tctatatcag ctagggattc tcctcgtccg agagcatctc cagctctcca gttacgagag
    25261 tggatggaag ttcccgttac gatcaaatct cccacaccag ataagccgct ataggtcaat
    25321 ggactggccc cgagtgctac ccctaggcgg gtgatttctg ctaaacctcg agcgatgatg
    25381 gctgccttag cattatcacc aaatccaaga ccatgtaaag ctccagcacc gacagcaata
    25441 atatttttaa gagcaccagc agtttcaacc ccgataacat ccgtattggt ataaagtcgg
    25501 aagtagtgat tactaaatag ctcctgaacg tattgagctg tttgtaaatc tttagaagca
    25561 gcagttatta aagttaggtc acgcacaatg gtctcttctg catgactagg ccctgaaaca
    25621 acgacgatat cactacggag atgttcagga atttcttctt caagaatggt tgataatcgt
    25681 ttatggctat caggttctaa tccctttgat gcgtgcatga tgataacctt atggtccaag
    25741 gtttgtgcaa cttgctgggc aacaagtcgt gtcacttttg ttgggacaac aaacaaaatc
    25801 gcatccacat ttttcaatgt ttctgctaag tcggtgtagg caatgatatt ttcgtctaga
    25861 acgacatctt taaagtagtg cttattagta tggtgtgtat taatttcatt gatttgctcg
    25921 ggaagatttc cccaaatacg tacctcgtgt ccattgtcat ttaagacttg tgaaagggcg
    25981 gttccccaag aaccaggccc caagacggcg acggtttgtt tttccatgat ttcctccttg
    26041 atagatttct ttctcttatt ctatcatatt ctaggggatt ttgcacttgc attactgggg
    26101 tatggtggaa aaatacacaa agaccgagat gaagggataa actcttagtc tttagttaaa
    26161 gtgagaagaa atctgataga tagtttgatt cagtatatgc ttataataga ggtaaacaac
    26221 tcaggaagtt cttgtaggtt gcgagagttt ggcgaaaaaa ttaaaagatt acgtttggct
    26281 aaaaaaatca gtcgttcaga attttgtggt gatgagtctg aattaagtat ccgtcaatta
    26341 attagaattg aaaatggaga atccagacca acactaacaa agttaaaata tattgctgaa
    26401 cgtttggagg ttgaagatta caagttgatg ccaagttata tagagttgga taaggaatac
    26461 ctagaattga agtatttctt gatgaggact cctacatacg aagatgaaac tatcgcccaa
    26521 aagaaagaga gtgtttttga taagattttt gaagagtatt atgataggct acctgaggaa
    26581 gaaagattta tcatcccaaa ttattcatat ctagcactag cgaactacac agttcaaaaa
    26641 ttaccagaaa agctagttga aatactgtcc ttctggtgat tttgcttaat ttctgatgtt
    26701 cgagacatga ttgaggagat ttgtcttgat tttttcctaa aaaagggcag actcctccct
    26761 tggtttgatg ctcgattttt aaaataaggt gacttattct gttaggcagt tttcccctgc
    26821 cctctagctc tatatggaac agggagtatc agatttatct ggcagattgt atcaaataag
    26881 gcttgaaact gttttgaata ggcgtataga cttgagaatt tgagaatatg tcgtctagca
    26941 gtagagacat attttccggc aatatgaagg aagagacgtc gaaaacgctt gatagtcaag
    27001 gcctttactt catcaccagc tagctgcttt aaaaagaggt agagattata agccagacag
    27061 cccatcatca tacgtacttc attcttaatc atggtcgaac tatctgtctt atccccaaag
    27121 aatcctgctt tcctttcttt gataaagttt tcagcattcc ctcgttcacg atagaattga
    27181 aacagctcct cactatctac actgcttaaa ttggtcaaat gaactttttt acaaccataa
    27241 aaaagagcac ttaatcgtac tcttctcttt taaggattag ttgaattaat tcaaatccac
    27301 tagttctcct gtttctaggt agactaggcg ttcacaaatg ttagcaatgt aatcagcgaa
    27361 gcgttccaga tgccctatga tataaaggta ttgagttcca ttgggaattg aggtttcttg
    27421 gtctttcata agtccaatga tttcctttga taaggcataa taatattggt caatctgttc
    27481 atctttttga gcaatactaa tagcttttga ggcttggtgc aaaggaaagg caaccaataa
    27541 atcggctagc atgctgaggg ataatttacc catttggtgt aactgttctt cgtcaggggc
    27601 tagttgattt tcttttagtt gcaaaacagc tttggcaatg cctgccatat ggtctcccat
    27661 acgttcaagg tctgaacaag aagacatgat gctaatcaca aatcgaaggt cagacacttg
    27721 tggctgctgc aaggccaaca aacgggcaca ggtcaattcg atagcgcttt gaccttggtt
    27781 gatagcatga tccttattga taattagctc tgccatctcc ttgtctttgg aggctaaggc
    27841 cagtaaggct tttgaagctg tttcaaggac aagttgccct agtcctaaaa aggattgttc
    27901 taattcatgc aattctaagt caaattgatt tctcataggt ttttccttcc ttatccgaac
    27961 cgtcctgaaa tatagtcttc tgtgcgctga tcttttggat tggtaaacac gtcaacggta
    28021 tctccaaatt cgcaaatttc tcctgttaag aaaaaagcag ttttatctga aatacgtgaa
    28081 gcttgttgca tgttatgggt aacaatgata atcgtataat ccttttttag ttgctgaatg
    28141 aggtcttcaa tttttaaagt ggagataggg tctaaggctg aagtcggctc atccattaac
    28201 agaatatcag gttctactgc taaagctcgc gcaatgcaaa ggcgttgctg ctgaccgcca
    28261 gataaggaca tagcactctt tttaagatca tctttgactt cttcccaaat ggctgcccct
    28321 tttaaagatt tctccactaa ggcatctaat tgttttttgt ctcgaatacc atgtgtcctt
    28381 gggccataag ccacgttatc atagatagac atggcaaagg gattaggctg ttgaaaaacc
    28441 atccctacac gcttacgtag ctgattaagg ttgaatttgc tactataaat atcttgctca
    28501 tctaagagga cttggccttc aatatggcaa gaaggaacca aatcgttcat ccggttaagg
    28561 gtttttagaa aagttgattt gccacaacca gatgggccta tcaaggcagt aatctgtctt
    28621 tctggtaatt gaatcgaaat attttttaag gcttgaaaat ccccgtaaaa taagtctagg
    28681 tgtctgactg aaaatgttcc catactagga agctcctttc acaagttttc gagataataa
    28741 gcttgataga gtatttatca ttaaaacagt aataatcaaa atcacaccgg tagcataggc
    28801 ttcattgaca tgtagcccct cacttgacag catatacata tgcagggcta gagaacgacc
    28861 tgaagacatg agactacttg gcgtattggt agaggtacct aatgtataca tgagggcagc
    28921 tgtctcacca acgatacggc caatagctag tatcactcca gctaaaatac ctggcatggc
    28981 aactggtaga acaattctaa aaacagtccg taacttacct gccccaagtc cataacttgc
    29041 ttgacgcatg atatcactaa cagataaaag ggcttcttct gttgagcgaa taatgactgg
    29101 caacaccatg atgactgagg ttaagattcc tgataacaga gagtattgaa aacctaagaa
    29161 gactacaaag aagagcatgc caaacagacc aaaaacaatg gaaggaatcc cagacaaggt
    29221 atctgaggcc aatcgcatga ttttaacaca aagggaatct ttttttgtat attccacaag
    29281 ataaaaacca gcaaaaatcc ctatgggcaa ggctaaaaga agagcaccaa agaccagaat
    29341 aacggtggaa ataatcgctg gcataaggga aatgttctca gaagtataag tccaagaaaa
    29401 gagggataga cttagatgag gtaagccttt gatgaggata aaaccaatga ttaaaaagag
    29461 agagccaaag gttaaagctg aaaaacaata aacgagaagt tttagcaggt atttactcat
    29521 aagatgattt tcctttcaag taggcaaagt aggcattaat caagagaata aggaaaaaga
    29581 gaactgctga ggttgcaata agggcttccc tatgctgacc tgatgcgtaa gccatttcca
    29641 gaacaatatt ggttgttaag gttctggttc ctgaaaagag tccacttgga ataatcggct
    29701 ggttgcctgc caccaaaata actgccatgg tttcacctac tgcgcgaccg attcctaaaa
    29761 taactgctga taaaatacca gatctcgcag ctggcaagat gacactaaaa atactccgtt
    29821 catgactagc tcctagagcc aagctaccag aataatacgt tttgggaact gttcggatag
    29881 cagattctga caaactgata atggttggca aaatcattat tcctaatagt aacgaagcgg
    29941 ttaggacact catgccattt cctaaaaagc ttctaatcca aggcaccaat aattgtaggc
    30001 cgaaaaaacc ataaacaata gatggaatgg ccgccatcaa gttgatagct gattttaaga
    30061 agccatagac gggctttgga caataataaa ccataaacac cgatgtcaag atgcctgttg
    30121 gcaccccaat cacaatcgct cctaaggtaa ttaataagga accaacgatc attggtaaaa
    30181 taccatagct tgccggaatg ttcgttggcg accaatcact gcctaataaa aaacgggcaa
    30241 agccgtagtt agccatgaaa ggtaagccat tactaaaaat aaagaaacag attagcaaaa
    30301 tagctacaac agctactgtt gcactcatga aaaaaattgc cctaaaaact gcttctttga
    30361 aggcttgttt tatcacatct tgtcctttct agtgaagaaa gtaagggaga tacgacacct
    30421 ccctacttgc cttctttatc ttattgtacg atgaaacgtc tgcatctctt tagagattta
    30481 tggagcaaac attttattta atcttgtccc aggtggttaa tttgccacta aaaacgtctg
    30541 caagttcagc catactgact tggcttgcct tattgtcatt attgaccaca acagcaatac
    30601 cgtctaaagc aatagcatca tgggtgagac tcttaccttc ttcaggagtt aattccctag
    30661 aaaccatacc aatatcagcg gttttctcct taacagcggt aatacctgct gaagacccat
    30721 tagaggtaat atcaatcgta acttctggat tttctttttt ataagcttct gctaattttt
    30781 ccattaaaga agatactgaa gtggaaccta caacagacaa cttgcctgat aagtgttggc
    30841 ttgtatattc tgtggtttca gttttagctt caataaattt attatctgtg accacttgtt
    30901 gaccttgttt ggagtggata aagctgataa aatcttgacc tagcttggaa agattagaag
    30961 accaaacaat gttgaaggga cgttgaagag ggtattcacc atctaaaact gtgtctcgac
    31021 tagccttgac accatcaatc tctaaagcct tgacagattt cgttaaagat cccaaggaga
    31081 tgtagccgat agcattagca ttcccttgaa ctgctgagag aacaccttct gtactatttt
    31141 gaatcacagc tgttttggca gtgttgtcaa tttttttatc accgtctttt ttgagaatcc
    31201 ctgtgatttc tgtgaaggca ccccgtgttc cagagccatt ttctcgtgaa atcacctcaa
    31261 tcgttcctga agctgactgt ttggaagcag ctgactgatt gccacaggca acaagcccaa
    31321 atcctgataa gccaatggct gcaagagtaa gcattttttt gaatttcata ataatcacct
    31381 ttatctctat gtatttttct tgtgtaggct tactacattt atagtctaac aagtctttgt
    31441 aaaggtttat ccctgattca tgtaaagatt gtgtaaagaa tcaaaaaaag ccacttttga
    31501 aaaatggctg ctcctaaaaa tagctttaaa aattattagt cctgtgcgaa agattggtta
    31561 ggaagaaaaa tcgtgaagca actgcctctg ccaagctgac ttgtcaccgt gacttggcca
    31621 cctaataatt gactgagttc tttgacaatg gcaaggccaa gaccagtgcc accagtttgt
    31681 ctgcttcgac ctttattaac tcggtaaaaa cgttcaaaaa tacgatcctg ctctaattga
    31741 ctaataccaa tccctgtatc tgatacagaa atcttaatgc cttcgttcac cttttgggtc
    31801 ttgacctcaa tttttccccc ttgttcagtg taacggatgg cattggataa aagattgagt
    31861 aagatttggg aaagtaattg actatctgat acgagggtga catcatctgg cacctgcacc
    31921 tttagctgta aatccttctt cttgagctga ggttgcaagc tttgagtcaa atcctgtaca
    31981 aattctgcca aagaaagggt cgtccattgt ataggcattt gttgagcctt agataaggta
    32041 agaagatgct caacaatatg ctcaagacgc aagctttctt tgtaaataat gtctagaaag
    32101 tcatccttga gcgcttcttc ttcagcagac atccccttaa tggtttcagc aaagccctta
    32161 atcgaagtaa ctggtgtcct caattcatgg gaggcatttg agacaaaggc taaatttaac
    32221 ttttcataag ttctaatcgt tgttaaatca tatagcaaga cgagcacagc ttccacagat
    32281 tgggtggggc taaaaacggg aactgctgtc acttctaaaa tcaagtcacc ctcatgaaac
    32341 ccacttactt cttgttttaa ccttgttttt tgatcaaagg cttggtgaac taaatttcga
    32401 atatccatcc gtttgaggtc atcaagtgaa cttatgtcgc cgtccacatc gggaaaataa
    32461 tgaggcagag agcgactgga taataacatc tgaccttgag cggaaactaa aaacgtcccc
    32521 atggttaggt gcgacagaag aacctccatt gtttcggcta ggtccttgta ttgctgatcc
    32581 tgttgggaga ctttggtttt taggccagac acatactgag ccaaagactt taagtcttct
    32641 tgcccttttt ctaaaaagta ttcactactg gtcaagagag gttggtgcaa ggtctcaaaa
    32701 gcaacttccc atttccaaag gcaaaagagc cagtagccac cttgtcccaa agaaagggct
    32761 agaagaaaga gaccgatgcc tttactgatc caagttaatg ccatccctgc aatcagaatg
    32821 aggctaacac ttagattgac tagccaaaat tgaaggtagc gtttcatcta taactccttg
    32881 aacttataac cataaccccg aatggttcga ataaattgag gggctttagg attgtcttca
    32941 attttttccc tcaacttacc aatatgaacg tccaccaaac gtgtttcctg cccaaagtca
    33001 tacccccaga tacgttccaa aagacgctct ctagtcagtg tcatgttggg atgtttcata
    33061 agatagagca agagttcaaa ttcttttggg gtcaaactca gtaacttatt cgccttgtag
    33121 acttcatgac gctcagggta tactttcaag gtcccaaata gccaagaatc gtcagcgata
    33181 ttatctgaat catctccttc ttgttctcct ttagttcgcc tgaggacagc cttgacacgc
    33241 gccagcaatt ctctagggct aaaaggcttg gtcaggtagt catcagcccc taattccaag
    33301 gccaaaacct tatcaaattc atcacttttc gcagaaacca tcataattgg agttttgacg
    33361 cctttggctc tcagccgctt acaaacttcc atgccatcta attgtggtaa catgatatca
    33421 agcaagataa aatcaaaggg ttctgtttct gccaaagcta aggccttccg tccatttgtt
    33481 accaattgag tagaaaagcc ttccttactt aaatggtagt caagcaattt cagaatgtgt
    33541 tcttcatcat ccactaataa gacttgtttt gtcatctatt atctcctatt ggtaacatta
    33601 taacacaatt atcagaaatc ctaacattgc taaatcagat taaatttgcc tatcaagact
    33661 agtatctggt caaacgctca atcatctcct tgtgctctgg ataggtcgcc agtagatcta
    33721 ccctttcaaa taattcaaaa tcctcaaatt caaaaccagg agcaacaaga caagaaacca
    33781 gagcatcatc cttatcaact gttgatcccc aaatagtgcc cttaggaaca cagtagtgaa
    33841 gttgttgccc tttggatatg tccaggccta aagtgactgc ttcgtagtga ccatctgctg
    33901 taatcatgtg aacagtaagt ggggatcctg catgaaaata ccagatttca tctgctgtca
    33961 atcggtgaaa atgtgaagga ttcgtttctt ctaataagaa ataaatactg gtataaagcg
    34021 cccttccctt accagcaagg tttatagtgt ctgaagcttt ttttgtttgt ctaaaatagc
    34081 caccttcaac atggggagct aactctagag ttcttatcaa gtcttcttta tccgtcggag
    34141 ccaatgggtt gaagtaactc ttgttcaaag tggttttacg atttcaagaa ctcctctcag
    34201 ttctgaggac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaag
    34261 aattagcgaa tgattctggt aaaaagaaat ttcacgctat gaaggctcaa gcgattgtca
    34321 caagtcaagg gagaattgtt tctattgcca tgatatgaag ttgttcaaaa tgagttgcag
    34381 aaatatcgga aaagctggta aaatcttggc tgacagtgat tatcaagggc tcatgaagat
    34441 atatcctcaa gcacaaactc cacgtaaatc cagcaaactc aagccgctaa cagctgaaga
    34501 taaagcctgt aaccatgcgc tatccaagga gagaagcaag gttgagaaca tctttgccaa
    34561 agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat catcgtaaac gcttcggatt
    34621 acgaatgaat ttgattgctg gtattatcaa tcatgaacta ggattctagt tttgcaggaa
    34681 gtctattatt tggttaggtg aattagtgaa gtgtttaggc aagtgtctct ggttacgacg
    34741 tcatggcctc taaatcgatt atatttaggg gtcatgacta gtgaagcagt tagctagttc
    34801 gcatataagc ggctagcgtc taacaattag gaactttagt tccaataact ttaagattac
    34861 gacgttttag gacataaatc gatcatattt atgtcctaaa actagtgaag cgcctagcca
    34921 aagtccgaat aggatttggc gttagttact tagattgctt tgcaatcaag taactttggc
    34981 gatttacatc ttctctggcg cttctactcc aagcaagcga agggcttctt tgagaacgac
    35041 tgcggttgcg tagctgaggg ctagacggct gtcgcgttct gggctttcat ccaagatacg
    35101 tgtatgtgca tagtatttgt taaaggattg agccaggcta attgcaaatt tagcaatgat
    35161 agaaggttca aagttatctg ccgcacggtt gataatacgt gggaagtctt gaatgagttt
    35221 aatgatttcc cagctttcag tatcattcaa gctatagttg ccagctgttt ctggtttgaa
    35281 atcggctttg cgtaagatag attggatacg agcgtaggca tattgaacgt aaggtccagt
    35341 ttcaccctcg aaggatacca tagcttctag gtcgaagtcg tatccatttg tacggtcagt
    35401 tttgaggtca tagaatttaa tggctccaac cccaacagca tgtgctactt ggtctttgtt
    35461 ttctagttca ggatttttag cctcgatttg gaccttggca cggctaacag cctctgcaac
    35521 agtaggctct agcaagatga cattcccttt acgagtagag agcttcttcc cttcttttgt
    35581 aaccagacca aaaggaacgt gggtaatgtc gtcactccaa tcgtagccca tctcttgcaa
    35641 gacagctttg agttgtttaa agtgggcaga ttgctcttga ccaacgacgt agatagattt
    35701 agcaaattgg tattcatttt tacggtagag ggctgcagcc aagtcacgtg tgatatagag
    35761 agttgcacca tcagacttct tgatgagggc tggatgttca attccatatt tctcaagatt
    35821 cacaacttgg gcaccttctg attcaagaag tagtcctttt tcagaaagaa tgtctacaac
    35881 tgcatccatc ttatcattgt agaaggcttc tccgttatag ctgtcaaatt caaccttcaa
    35941 ttcattgtaa aggcggttaa attccactaa actttcatcg cggaaccatt gccaaagagc
    36001 gagagcttcc tcatctccat tttcaagttt acggaaccat tcgcgcgctt cttcatccaa
    36061 gctagggtca ttttcagctt cagcgttgat gcggacatag agtttaagga gttcatcgat
    36121 tggatgagct tttacagctt cttcgtcgcc ccattttttg taggcaacaa tcaacatccc
    36181 aaattgttta ccccagtctc ccaaatggtt gaccttgacc gtttgataac cgattttttg
    36241 gaaaatatgt gacaagctat ctccgataac agttgaacgc aggtggccaa tagaaaatgg
    36301 tttagcgata ttcggactag acatgtcgat aacaacattt tcttgtttgc caatattttg
    36361 gtcagcatag tgttcttttt cagtggtaac agcttgcaat acttgagcag aaatggcaga
    36421 tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca actttttcaa aggcttggct
    36481 gttcattttt tcagccagtt cagccgcaat catttgtggt gctttacgtt cgacttttgc
    36541 aagagaaaaa gcagggaaag caatgtctcc catttctgag tttttagggg tttccagtaa
    36601 ctttaaaata gcctcttggt ccaggctatc aatgatgcta gataattcgc tagcaatcaa
    36661 ttcttttgta ttcattaaga gctccttttt ggacttttct actattttat cacaatttta
    36721 aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg gtataatatg gttataaata
    36781 tagttataaa tatgcacgca agaggatttt atgagaaaaa gagatcgtca tcagttaata
    36841 aaaaaaatga ttactgagga gaaattaagt acacaaaaag aaattcaaga tcggttggag
    36901 gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg atttgcgcga aatcggcttg
    36961 accaaggtca agaaaaatga tatggtgtat tatgtactag taaatgagac agaaaagatt
    37021 gatttggtgg aatttttgtc tcatcattta gaaggtgttg caagagcaga gtttaccttg
    37081 gtgcttcata ccaaattggg agaagcctct gttttggcaa atattgtaga tgtaaacaag
    37141 gatgaatgga ttttaggaac agttgctggt gccaatacct tattggttat ttgtcgagat
    37201 cagcacgttg ccaaactcat ggaagatcgt ttgctagatt tgatgaaaga taagtaaggt
    37261 cttgggagtt gctctcaaga cttatttttg aaaaggagag acagaaaatg gcgatagaaa
    37321 agttatcacc cggcatgcaa cagtatgtgg atattaaaaa gcaatatcca gatgcttttt
    37381 tgctctttcg gatgggtgat ttttatgaat tattttatga ggatgcggtc aatgctgcgc
    37441 agattctgga aatttcctta acgagtcgca acaagaatgc cgacaatccg atccctatgg
    37501 cgggtgttcc ctatcattct gcccaacagt atatcgatgt cttgattgag cagggttata
    37561 aggtggctat cgcagagcag atggaagatc ctaaacaagc agttggggtt gttaaacgag
    37621 aggttgttca ggtcattacg ccagggacag tggtcgatag cagtaagccg gacagtcaga
    37681 ataatttttt ggtttccata gaccgcgaag gcaatcaatt tggcctagct tatatggatt
    37741 tggtgacggg tgacttttat gtgacaggtc ttttggattt cacgctggtt tgtggggaaa
    37801 tccgtaacct caaggctcga gaagtggtgt tgggttatga cttgtctgag gaagaagaac
    37861 aaatcctcag ccgccagatg aatctggtac tctcttatga aaaagaaagc tttgaagacc
    37921 ttcatttatt ggatttgcga ttggcaacgg tggagcaaac ggcatctagt aagctgctcc
    37981 agtatgttca tcggactcag atgagggaat tgaaccacct caaacctgtt atccgctacg
    38041 aaattaagga tttcttgcag atggattatg cgaccaaggc tagtctggat ttggttgaga
    38101 atgctcgctc aggtaagaaa caaggcagtc ttttctggct tttggatgaa accaaaacgg
    38161 ctatggggat gcgtctcttg cgttcttgga ttcatcgccc cttgattgat aaggaacgaa
    38221 tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca tttctttgag cgtagtgact
    38281 tgacagacag tctcaagggt gtttatgaca ttgagcgctt ggctagtcgt gtttcttttg
    38341 gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac cttgtctagt gtgccacgga
    38401 ttcgtgcgat tttagaaggg atggagcaac ctactctagc ctatctcatc gcacaactgg
    38461 atgcaatccc tgagttggag agtttgatta gcgcagcgat tgctcctgaa gctcctcatg
    38521 tgattacaga tgggggaatt atccggactg gatttgatga gactttagac aagtatcgtt
    38581 gcgttctcag agaagggact agctggattg ctgagattga ggctaaggag cgagaaaact
    38641 ctggtatcag cacgctcaag attgactaca ataaaaagga tggctactat tttcatgtga
    38701 ccaattcgca actgggaaat gtgccagccc actttttccg caaggcgacg ctgaaaaact
    38761 cagaacgctt tggaaccgaa gaattagccc gtatcgaggg agatatgctt gaggcgcgtg
    38821 agaagtcagc caacctcgaa tacgaaatat ttatgcgcat tcgtgaagag gtcggcaagt
    38881 acatccagcg tttacaagct ctagcccaag gaattgcgac ggttgatgtc ttacagagtc
    38941 tggcggttgt ggctgaaacc cagcatttga ttcgacctga gtttggtgac gattcacaaa
    39001 ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt tatgggggct cagacctata
    39061 ttccaaatac gattcagatg gcagaagata ccagtattca actggttaca gggccaaaca
    39121 tgagtgggaa gtctacctat atgcgtcagt tagccatgac ggcggttatg gcccagctgg
    39181 gttcctatgt tcctgctgaa agcgcccatt taccgatttt tgatgcgatt tttacccgta
    39241 tcggagcagc agatgacttg gtttcgggtc agtcaacctt tatggtggag atgatggagg
    39301 ccaataatgc catttcgcat gcgaccaaga actctctcat tctctttgat gaattgggac
    39361 gtggaactgc aacttatgac gggatggctc ttgctcagtc catcatcgaa tatatccatg
    39421 agcacatcgg agctaagacc ctctttgcga cccactacca tgagttgact agtctggagt
    39481 ctagtttaca acacttggtc aatgtccacg tggcaacttt ggagcaggat gggcaggtca
    39541 ccttccttca caagattgaa ccgggaccag ctgataaatc ctacggtatc catgttgcca
    39601 agattgctgg cttgccagca gaccttttag caagggcgga taagattttg actcagctag
    39661 agaatcaagg aacagagagt cctcctccca tgagacaaac tagtgctgtc actgaacaga
    39721 tttcactctt tgatagggca gaagagcatc ctatcctagc agaattagct aaactggatg
    39781 tgtataatat gacacctatg caggttatga atgtcttagt agagttaaaa cagaaactat
    39841 aaaaccaaga ctcactagtt aatctagctg tatcaaggag acttctttga caattctcca
    39901 cttttttgct agaataacat cacacaaaca gaatgaaaag gagctgacgc attgtcgctc
    39961 ccttttgtct attttttaag gagaaagtat gctgattcag aaaataaaaa cctacaagtg
    40021 gcaggccctg gcttcgctcc tgatgacagg cttgatggtt gctagttcac ttctgcaacc
    40081 gcgttatctg caggaagtct taggcgccct ccttactggg aaatatgaag ttatttatag
    40141 tatcggggct tggttgattg gtgtggccgt agtcggtcta gttgctggtg gactcaatgt
    40201 tgtcctcgca gcctatattg cccaaggagt ttcatccgac cttcgggagg atgccttccg
    40261 taaaattcaa accttttctt atgctgatat tgaacaattt aatgcgggaa atctagtcgt
    40321 tcgaatgaca aatgatatca accagattca gaacgttgtc atgatgacct tccaaattct
    40381 tttcagactt cccctcttgt tcatcggttc gtttatccta gcggttcaaa ccttaccttc
    40441 tctgtggtgg gtgattgttc tcatggtagt cttgattttt ggtttgactg ctgtcatgat
    40501 gggaatgatg gggcctcgtt ttgctaaatt tcaaaccctt cttgagcgca tcaatgccat
    40561 tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc tttgtccaag aaaaagagca
    40621 atttgctaag tttacagagg tctcagacga gcttcttggt caaaaccttt acattggtta
    40681 tgccttttca gtagtggaac cctttatgat gttggttggt tacggggcgg tcttcctctc
    40741 tatttggctg gtcgcgggaa tggttcagtc ggatccgtct gttgttggtt ccatcgcttc
    40801 ttttgttaat tacctaagcc agattatctt taccattgtt atggttggat ttttgggaaa
    40861 ttctgtcagc cgtgccatga tttccatgcg tcgtattcga gaaattcttg acgcagagcc
    40921 agctatgacc ttcaaggata tcccagatga agagttggtt ggaagtctta gctttgaaaa
    40981 tgtgaccttt acctatccaa tggacaagga accgatgctg aaagatgtga gctttactat
    41041 tgaacctggt caaatggttg gtgtagttgg agcgactggt gcaggaaagt caaccttggc
    41101 tcaattgatt ccacgtctct ttgatccaca ggacggggcc attaaaatcg gtggcaagga
    41161 tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt tccatcgttc tccaacgtgc
    41221 cattcttttt agtggaacga ttgcagataa cttgagacag gggaagggga atgctactct
    41281 atttgaaatg gagcgcgcag ccaatattgc ccaggctagt gaattcattc atcgtatgga
    41341 gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat ttctctggtg gacaaaaaca
    41401 aaggatgtcg attgcgcgtg ggattgtcag caatccacgt attctgattt ttgacgattc
    41461 gacctcagcc ttggatgcca aatcagagcg cttggtgcaa gaagctttga ataaggactt
    41521 gaaggggacg acaaccatta ttattgctca aaaaattagc tcggttgtcc atgcagacaa
    41581 gatcttggtt ctaaatcaag gacgattgat tggtcaaggc acgcatgcag acttggttgc
    41641 caacaatgcc gtttaccgtg aaatctatga aacacagaaa tgaaagacaa actataagaa
    41701 aagtcaatag ttttatctaa actatttctt atttcaattt gatgatttgg cgatgatttt
    41761 agagcacggc aaaaagccct tgaaaaagtc cattttttca aaggtaatcc tgtgttgatt
    41821 tcagaaatta catcactttt tgttcgtcaa atggcagctc ttttttagga tataaaacag
    41881 ggttcggata agtttttttg caaggtggat gatggctaca ttgtaatgtt ttccttattc
    41941 taacttagtc ttaagatagg ccttaaaagc aggtgaaaag cgagcgcatg ctttggcagc
    42001 ttgtatgagt gcctaccgca gatgagggga accccgtttg atcattcttc cagctaaatc
    42061 aatctgacct gactgataaa tagaagaatc cagtccagcg aaagcttgta attgagcagg
    42121 attatcaaag gcatgaatat tttgaatctc ggctaaaatg accgccccta aacgattccc
    42181 aatcccagta accgtcgtga tgaccgaatt taactcagcc atcaagtcat tgacacattt
    42241 ttccgccttg tcaatgagcc tcttgtaatg tttgatgttt tcattacacg agataaaacg
    42301 tctatgcgtt atcaaactca ttaccaatta aaacaaatgt ggttagatcc tttcggaaat
    42361 tgtcaagcga ttggaggaaa tgaactaatc cacagcggct tattccaagt ataccacttg
    42421 ggctttggca gtagctaact gcgctaaata taatataagg aggagtaaaa tgaagacagt
    42481 tcaatttttt tggcattatt ttaaggtcta caagttctca tttgtagttg tcatcctgat
    42541 gattgttctg gcgacttttg cccaagccct ctttccagtc ttttctggac aagcggtgac
    42601 gcagctagcc aatttagttc aagcttatca aaatggcaat ccagaacttg tatggcaaag
    42661 cctatcagga atcatggtca atcttggcct gctggttttg gttctattta tctctagtgt
    42721 aatatacatg tgtctcatga cgcgcgtgat tgcagaatcg accaacgaga tgcgcaaagg
    42781 tctctttggt aagcttgctc agttgacggt ttctttcttt gaccgtcgac aagatggcga
    42841 tatcctgtct cattttacca gtgatttgga taatatcctc caagccttta acgaaagctt
    42901 gattcaggtc atgagcaata ttgttttata cattggtctg attcttgtca tgttttcgag
    42961 aaatgtgacg ctggctctca tcaccattgc cagcacccca ttggctttcc ttatgctgat
    43021 tttcatcgtg aaaatggcac gcaaatacac caacctccag cagaaagagg tagggaagct
    43081 caacgcctat atggatgaga gcatctcagg ccaaaaagcc gtgattgtgc aaggaattca
    43141 agaggatatg atggcaggat ttcttgaaca aaatgagcgc gtgcgcaagg caacctttaa
    43201 aggaagaatg ttctcaggaa ttcttttccc tgtcatgaat gggatgagcc tgattaatac
    43261 agccatcgtc atctttgctg gttcggctgt acttttgaat gataagtcta ttgaaacaag
    43321 tacagcccta ggtttgattg ttatgtttgc acaattttca cagcagtact accagcctat
    43381 tatccaagtt gcagcgagtt ggggaagcct tcagttggcc tttactggag ctgaacgaat
    43441 tcaggaaatg tttgatgcag aggaggaaat ccgacctgaa aaggctccaa ccttcactaa
    43501 gttgcaagaa agtgttgaaa tcagtcatat cgatttttca tacttgcctg ataaacctat
    43561 tttgaaagat gtcagcattt ctgcccctaa aggccagatg acagcagttg ttgggccgac
    43621 aggttcagga aaaacgacta ttatgaacct catcaatcgc ttttatgatg ttgatgctgg
    43681 tggtatttat tttgatggta aagacattcg tggctatgac ttagatagtc ttagaagcaa
    43741 ggtgggaatt gtattgcaag attcggtctt gtttagcgga acgattcgag acaatatccg
    43801 atttggtgtg ccagatgcta gtcaggaaat ggttgaggta gcagcaaaag caacccacat
    43861 tcacgactat atcgaaagtt tgcctgataa gtacgatact cttattgatg atgaccagag
    43921 catcttttca acagggcaga agcaattgat ttcaatcgct cgaaccctga tgacagatcc
    43981 agaagttctc attctcgatg aagcaacttc aaacgtagat acggtgacag aaaacaagat
    44041 tcagcatgcc atggaggtgg ttgtagcagg tagaactagt ttcgtcattg cccaccgctt
    44101 gaaaaccatt ctcaatgcag atcagattat tgtccttaaa gatggagaag tcattgaacg
    44161 tggtaaccac catgaacttt tgaagctagg tggcttttat tcagaactct atcacaatca
    44221 atttgttttc gaataagaaa gaagttgtcc tatgtgggca gctttttctt gtccataaaa
    44281 aatgtttatc acagccttaa aaaaaacata ttagacgaaa gtcattttga gtgatatgat
    44341 aggactatcg ttagcattcg aaaggagagg catcatggct agaacggttg taggagttgc
    44401 tgcaaatcta tgtcccgtag acgcagaagg caaaatcatt cattcatctg tatcttgtag
    44461 attcgcagag atcattcgtc aaatcggtgg tctcccttta gtcattcctg ttggtgatga
    44521 gtcagttgta cgtgattatg tggaaatgat tgacaaactc attttgacag gaggccaaaa
    44581 tgttcatcct cagttttatg gagagaaaaa gaccgtcgag agcgatgatt acaatctggt
    44641 ccgtgacgaa tttgaattgg cactcttgaa ggaagcgctt cgtcagaata aaccaattat
    44701 ggcaatctgt cgcggtgtcc aacttgtcaa tgttgccttt ggtggaaccc tcaatcaaga
    44761 aatcgaaggt cactggcaag gactaccttt cgggacatct cactctattg agacagtaga
    44821 aggaagcgtg gtggctaagc tatttgggaa agaaagtcag gtcaactcag tccatcgtca
    44881 aagcattaaa gatttggcac ctaatttccg tgtaactgct attgattcaa gagaccaaac
    44941 tattgaagct attgagtcta tcgacgagca ccgcattatc ggtttacagt ggcatccaga
    45001 gtttctggtt aatgaagaag atggcaattt agaattattt gagtatttat tgaatgaact
    45061 gtaacgattg gaacatctgg tcgttctttc ttttattttt tcaaaatttt tagaatgtgg
    45121 cattttacgc aaacgtttga attctgataa aaattggaga aattcgacaa aaaaacttga
    45181 aaaaaacgaa ggtaagcgtt atgatagaaa agaagaaata ttggaggaag aacatgtcac
    45241 atattaaatt tgattattca aaagttttag acaaatttgt tgcaccacat gaagtggaat
    45301 acatgcaatc acaagtaaca gcagcagatg aattgatccg taaaggaact ggtgctggta
    45361 gcgacttctt gggatggttg gaccttcctg aaaaatacga tcgcgaagaa tttgaccgca
    45421 tcttgaaagc tgctgagcaa atcaagtcag acagcgatgt tttggttgtg atcggtattg
    45481 gtggatctta ccttggtgca aaagcagcaa tcgacttctt gaatcaccat tttgctaact
    45541 tgcaaacaaa agaagaacgc aaagctccac aaatccttta cgcaggaaac tcaatctcat
    45601 ctacttacct tgctgacttg gtagagtatg ttgcagacaa agacttctca gtaaacgtaa
    45661 tttctaaatc aggtacaaca actgaaccag cgattgcttt ccgtgtcttt aaagaactct
    45721 tggttaagaa atacggtcaa gaagaagcta acaaacgtat ctatgcaaca actgaccgcc
    45781 aaaagggtgc tgttaaggtt gaagcagacg ctaacggttg gggaacattt gttgttccag
    45841 atgatatcgg tggacgcttc tcagtattga cagccgttgg tttgcttcca atcgcagcat
    45901 caggagctga catcaaagct cttatggaag gtgcgaatgc agctcgcaaa gactacactt
    45961 cagacaaaat ctctgaaaac gaagcttacc aatacgcagc tgttcggaac atcctttatc
    46021 gtaaaggcta tgcaactgag atcttggtaa actatgagcc atcacttcaa tacttctcag
    46081 aatggtggaa acaattggct ggtgaatcag aaggaaaaga ccaaaaaggt atctacccaa
    46141 cttcagccaa cttctcaact gacttgcact cacttggtca atttatccaa gaaggaactc
    46201 gtatcatgtt tgaaacagtt gtccgtgttg acaaacctcg taaaaacgtg cttattccta
    46261 ctttggaaga agaccttgac ggacttggtt accttcaagg aaaagacgtt gactttgtaa
    46321 acaaaaaagc aactgacggt gttcttcttg cccacacaga tggtgatgta ccaaacatgt
    46381 atgtgactct tccagagcaa gacgctttca ctcttggtta cactatctac ttcttcgaat
    46441 tggcaattgc cctttcaggt tacttgaatg ctatcaaccc atttgaccaa ccaggtgttg
    46501 aagcttataa acgtaacatg tttgcccttc ttggaaaacc aggatttgaa gaattgagca
    46561 aagaacttaa cgcacgtcta taatagaaga aaagagtggt ttgcccactc tttttactct
    46621 ctttatccat agaaattgga ctcagccaag acttgtgata taatatagaa agcaaaaagg
    46681 cagacgccta gataatagga gaaactatgt caaaagatat ccgcgtacgt tacgcaccaa
    46741 gtccaacagg actactacac atcggaaatg ctcgtacagc attgtttaat tacttgtatt
    46801 cgcgccatca tggtggaaca tttctcatcc gtatcgaaga tactgaccgt aaacgccatg
    46861 tcgaggatgg tgaacgttca caacttgaaa accttcgctg gttaggcatg gattgggatg
    46921 aaagtccaga atcacatgag aattatcgcc agtctgagcg tttggacttg tatcaaaaat
    46981 acattgacca actattagct gaaggaaaag cctataaatc ttacgttaca gaagaagagt
    47041 tggcagctga acgcgaacgc caagaagtag ctggcgaaac accacgctac atcaatgaat
    47101 accttggtat gagtgaagaa gaaaaagcag cttacatcgc agaacgtgaa gcagcaggga
    47161 tcatcccaac tgttcgtttg gctgtcaatg agtcaggtat ctacaagtgg catgatatgg
    47221 tcaaaggcga tatcgaattt gaaggtggca atatcggtgg tgactggatt atccaaaaga
    47281 aagacggtta cccaacttac aactttgccg ttgccatcga tgaccatgat atgcaaatct
    47341 ctcatgttat ccgtggagac gaccatattg ctaacacacc aaaacagctc atggtttatg
    47401 aagcacttgg ttgggaagct ccagagtttg gtcacatgac cttgattatc aactctgaga
    47461 ctggtaagaa gttatctaaa cgtgatacta atacacttca atttatcgaa gattaccgaa
    47521 agaaaggtta ccttccagaa gcagtcttta actttattgc tcttcttggt tggaacccag
    47581 gtggtgaaga tgagattttc tctcgtgaag aactcattaa actttttgat gaaaaccgcc
    47641 tcagcaagtc accagcagcc tttgatcaga aaaaactaga ctggatgagc aatgattata
    47701 tcaagaatgc agaccttgaa accatctttg aaatggcaaa accattctta gaggaagcag
    47761 gccgtttgac tgacaaggct gaaaaattag ttgagctcta taaaccacaa atgaaatcag
    47821 tagatgagat tatcccattg acagatcttt tcttctcaga tttcccagaa ttgacagaag
    47881 cagagcgcga agtcatgacg ggtgaaacag ttccaacagt tcttgaagca ttcaaagcaa
    47941 aacttgaagc gatgacagat gataaatttg tgacagaaaa tatcttccca caaattaaag
    48001 cagttcaaaa agaaacaggt attaaaggga aaaatctttt catgcctatt cgtatcgcag
    48061 tttcaggcga aatgcatggg ccagaattac cagatacaat tttcttgctt ggacgtgaaa
    48121 aatcaattca gcatatcgaa aacatgctaa aagaaatctc taaataaaga ggatacaata
    48181 atggacatct gggaaaagat gtacgaagaa gcacagaaac tatacaatcc acatgaagta
    48241 tcagactttg tttatgccaa tcatgttgta gctgcagtag aagcagaaga tggacaaata
    48301 tttacaggat tctgtatgga gggaacctgt ggtgttttcc atctctgcgc agaacgggcg
    48361 gccctcttca atatgtacca attttcagga caaactaagg ttaagaaagt attagccttt
    48421 cgagacaaac caccttatgg tggaagttca gccatgcctt gcggtgcttg tagagaattc
    48481 cttttagagc ttaatgctga aaataaagat gcagaattca tgatggacta taatataaga
    48541 aaaacagtta aagtcgcaga actaatccct tattggtggg gagaagaacg tgcttctaag
    48601 tttaatgagc gatagaagag tcagtataat tctggctttt tttactataa gttgaaaaaa
    48661 taaaaaaaat ta
//
LOCUS       DAVLZG010000006        46590 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLZG010000006 DAVLZG010000000
VERSION     DAVLZG010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.006"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(613..1026)
                     /gene="ndk"
                     /locus_tag="VYO72_000352"
     CDS             complement(613..1026)
                     /gene="ndk"
                     /locus_tag="VYO72_000352"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1706793.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1137..4814)
                     /gene="rpoC"
                     /locus_tag="VYO72_000353"
     CDS             complement(1137..4814)
                     /gene="rpoC"
                     /locus_tag="VYO72_000353"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1706794.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4847..8458)
                     /gene="rpoB"
                     /locus_tag="VYO72_000354"
     CDS             complement(4847..8458)
                     /gene="rpoB"
                     /locus_tag="VYO72_000354"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1706795.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8874..8944
                     /locus_tag="VYO72_000355"
     tRNA            8874..8944
                     /locus_tag="VYO72_000355"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8906..8908,aa:Cys,seq:gca)
     gene            complement(9142..10473)
                     /locus_tag="VYO72_000356"
     CDS             complement(9142..10473)
                     /locus_tag="VYO72_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1706796.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10764..11588)
                     /gene="endA"
                     /locus_tag="VYO72_000357"
     CDS             complement(10764..11588)
                     /gene="endA"
                     /locus_tag="VYO72_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1706797.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11627..11815)
                     /locus_tag="VYO72_000358"
     CDS             complement(11627..11815)
                     /locus_tag="VYO72_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1706798.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11808..13091)
                     /gene="murA"
                     /locus_tag="VYO72_000359"
     CDS             complement(11808..13091)
                     /gene="murA"
                     /locus_tag="VYO72_000359"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1706799.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13115..13345)
                     /locus_tag="VYO72_000360"
     CDS             complement(13115..13345)
                     /locus_tag="VYO72_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1706800.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13403..14440)
                     /locus_tag="VYO72_000361"
     CDS             complement(13403..14440)
                     /locus_tag="VYO72_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1706801.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14424..14912)
                     /gene="coaD"
                     /locus_tag="VYO72_000362"
     CDS             complement(14424..14912)
                     /gene="coaD"
                     /locus_tag="VYO72_000362"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1706802.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14902..15441)
                     /gene="rsmD"
                     /locus_tag="VYO72_000363"
     CDS             complement(14902..15441)
                     /gene="rsmD"
                     /locus_tag="VYO72_000363"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1706803.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15506..16498)
                     /locus_tag="VYO72_000364"
     CDS             complement(15506..16498)
                     /locus_tag="VYO72_000364"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1706804.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16609..17292)
                     /locus_tag="VYO72_000365"
     CDS             complement(16609..17292)
                     /locus_tag="VYO72_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1706805.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17348..18088)
                     /locus_tag="VYO72_000366"
     CDS             complement(17348..18088)
                     /locus_tag="VYO72_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1706806.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18122..18400
                     /locus_tag="VYO72_000367"
     CDS             18122..18400
                     /locus_tag="VYO72_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1706807.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18478..19404
                     /gene="yidC"
                     /locus_tag="VYO72_000368"
     CDS             18478..19404
                     /gene="yidC"
                     /locus_tag="VYO72_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1706808.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19479..20273)
                     /gene="pflA"
                     /locus_tag="VYO72_000369"
     CDS             complement(19479..20273)
                     /gene="pflA"
                     /locus_tag="VYO72_000369"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1706809.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20399..21649)
                     /locus_tag="VYO72_000370"
     CDS             complement(20399..21649)
                     /locus_tag="VYO72_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1706810.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21716..22543)
                     /gene="purR"
                     /locus_tag="VYO72_000371"
     CDS             complement(21716..22543)
                     /gene="purR"
                     /locus_tag="VYO72_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1706811.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22810..23751)
                     /locus_tag="VYO72_000372"
     CDS             complement(22810..23751)
                     /locus_tag="VYO72_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1706812.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(23741..24997)
                     /locus_tag="VYO72_000373"
     CDS             complement(23741..24997)
                     /locus_tag="VYO72_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1706813.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24999..25661)
                     /locus_tag="VYO72_000374"
     CDS             complement(24999..25661)
                     /locus_tag="VYO72_000374"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1706814.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25624..26280)
                     /locus_tag="VYO72_000375"
     CDS             complement(25624..26280)
                     /locus_tag="VYO72_000375"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1706815.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26291..27169)
                     /gene="rsgA"
                     /locus_tag="VYO72_000376"
     CDS             complement(26291..27169)
                     /gene="rsgA"
                     /locus_tag="VYO72_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1706816.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27171..28043)
                     /gene="rsmA"
                     /locus_tag="VYO72_000377"
     CDS             complement(27171..28043)
                     /gene="rsmA"
                     /locus_tag="VYO72_000377"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1706817.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28429..28575)
                     /locus_tag="VYO72_000378"
     CDS             complement(28429..28575)
                     /locus_tag="VYO72_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706818.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDKNMTNHLLLVQILVHGYLLDFA
                     SIEG"
     gene            complement(28568..29209)
                     /locus_tag="VYO72_000379"
     CDS             complement(28568..29209)
                     /locus_tag="VYO72_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706819.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29211..31241)
                     /locus_tag="VYO72_000380"
     CDS             complement(29211..31241)
                     /locus_tag="VYO72_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1706820.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31318..31614)
                     /locus_tag="VYO72_000381"
     CDS             complement(31318..31614)
                     /locus_tag="VYO72_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1706821.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31934..32833)
                     /locus_tag="VYO72_000382"
     CDS             complement(31934..32833)
                     /locus_tag="VYO72_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1706822.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32905..33465)
                     /gene="rnmV"
                     /locus_tag="VYO72_000383"
     CDS             complement(32905..33465)
                     /gene="rnmV"
                     /locus_tag="VYO72_000383"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1706823.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33465..34238)
                     /locus_tag="VYO72_000384"
     CDS             complement(33465..34238)
                     /locus_tag="VYO72_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1706824.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPMIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34543..35436)
                     /locus_tag="VYO72_000385"
     CDS             complement(34543..35436)
                     /locus_tag="VYO72_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1706825.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEVTPEY
                     KLETTPGGDKGGNIGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(35720..35854)
                     /gene="rpmH"
                     /locus_tag="VYO72_000386"
     CDS             complement(35720..35854)
                     /gene="rpmH"
                     /locus_tag="VYO72_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1706826.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35999..37213)
                     /locus_tag="VYO72_000387"
     CDS             complement(35999..37213)
                     /locus_tag="VYO72_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1706827.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37369..37662)
                     /locus_tag="VYO72_000388"
     CDS             complement(37369..37662)
                     /locus_tag="VYO72_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706828.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37811..38263
                     /locus_tag="VYO72_000389"
     CDS             37811..38263
                     /locus_tag="VYO72_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1706829.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38298..39686)
                     /locus_tag="VYO72_000390"
     CDS             complement(38298..39686)
                     /locus_tag="VYO72_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1706830.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELHRQL
                     KAYERHKERNKS"
     gene            39752..40714
                     /locus_tag="VYO72_000391"
     CDS             39752..40714
                     /locus_tag="VYO72_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1706831.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HTLDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLTMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40711..40902)
                     /locus_tag="VYO72_000392"
     CDS             complement(40711..40902)
                     /locus_tag="VYO72_000392"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706832.1"
                     /translation="MNTIERTRRLVKGCAIHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     NHTYGKATLTWFAEIFEEY"
     gene            complement(40966..41976)
                     /gene="ccpA"
                     /locus_tag="VYO72_000393"
     CDS             complement(40966..41976)
                     /gene="ccpA"
                     /locus_tag="VYO72_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1706833.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42401..43000)
                     /locus_tag="VYO72_000394"
     CDS             complement(42401..43000)
                     /locus_tag="VYO72_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1706834.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVAVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(43002..44099)
                     /locus_tag="VYO72_000395"
     CDS             complement(43002..44099)
                     /locus_tag="VYO72_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1706835.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(44099..44836)
                     /locus_tag="VYO72_000396"
     CDS             complement(44099..44836)
                     /locus_tag="VYO72_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1706836.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44838..45722)
                     /locus_tag="VYO72_000397"
     CDS             complement(44838..45722)
                     /locus_tag="VYO72_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706837.1"
                     /translation="MDMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELVAFFQSIY
                     PNPLSNQEIDQLLQFDKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(45709..45903)
                     /locus_tag="VYO72_000398"
     CDS             complement(45709..45903)
                     /locus_tag="VYO72_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706838.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQALLRQFIRGAWGLGFM
                     IFIAFPMGMEWLKGEYHGHD"
     gene            complement(45900..46091)
                     /locus_tag="VYO72_000399"
     CDS             complement(45900..46091)
                     /locus_tag="VYO72_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706839.1"
                     /translation="MKNKMIVAMSLVAAGVMTYLMFSGLDEDFYHFPWELFAGFGMMS
                     WLIREGLKLVSDVKKEFEK"
BASE COUNT        13335 a        10803 c         8834 g        13618 t
ORIGIN      
        1 ttattccatg ttattttgag gaagatattg tgaaagtcaa agatgatgat aaagttgagt
       61 ggaatttgtt agaatttcaa aaatttagag catttttgac ttagtaatct gtgttgaagg
      121 ctcaaaacct atggtaaaaa agtaactttg aaaacgtatt gcctccaaag atttagttaa
      181 ataatgattt aacacaaaaa gaaattattg aagttctgga aagatgttgt ttcagtattg
      241 agaaaaggtg ggaaaaactt gcgattttca cagagaaagg aagaaaaagt atagaaatat
      301 agtcaattga aacaagaaca ggataaaaga accttttgtg ccatattttt ctcctttcgc
      361 tttacaattg gattgaacac ctttattgta tcgcgtttgg agtttttttg gtataacctt
      421 cgacgcgcac ccgcatagcg ggtgtttttt tgtctcgcac ctaacggagc gagacgaact
      481 aatagtcact taatcaaaaa acgcaccata tcaaaaacta aaaagtttga tatcatgcgt
      541 catgtcttaa actaattgac tatactttct attcaaatga gcttttaacc aattgattga
      601 gccaatccac tcttaaaacc aaagagcaat ttctcgctta gctgactctt ctgaatctga
      661 accatgtaca acattttgga taacctcatt ttctccagca gcttttgcaa agtcacctcg
      721 aatagtgcct ggtaaagctt cttctggacg agttgcaccc atcatggtcc gccaagtttc
      781 gattactttg ggaccagaaa tgacacccac aagaactgga cctgaagtca tgaattcacg
      841 aatcggtggg taaaaactct gaccaaccaa gtcctgatag tgctggtcaa tcaactcttc
      901 tgaaacctgt gaacgaaact ccaatttttc gattgtaaat ccacgttgtt cgatgcgctt
      961 taacacttca cccactagcc ctctttttac accatctggt ttgatgataa agaatgtttg
     1021 ttccataccc gtctcctttg tcagcttctt tcttttattt taccacattt cgtggaaaaa
     1081 tggagaaagt tttcagaaga gagaatgaga gaacccgagg gttctctcat tctctcttat
     1141 tctactgttt cttccacagt ttcaacggca gtatccacaa ctacttctgt tgtttcttca
     1201 tttccttctt cctctactgg aggattaagg tattcttctt cgttgacagc atgtggttca
     1261 aggttacggt aacgggccat accagtacca gctgggatga tcttaccgat gataacattt
     1321 tctttaagtc caaggagatg gtctttctta ccacggatag ctgcgtcagt aaggacacga
     1381 gttgtttcct ggaaggaagc cgctgacaag aaactgtttg tttcaagtga ggctttggta
     1441 attcccataa ggactgggcg acctgtcgct ggaactccac ctgcgataag gacatctttg
     1501 ttggcatctg taaagtcatt gatatccatg agggtaccca tgagaagatc tgtatcacct
     1561 ggatccatga cacggacttt acggatcatt tgacgaacca ttacctcgat gtgtttgtca
     1621 ccgatttcta ccccttggct acggtaaact ttttgtactt caccgagaag gtacgtttca
     1681 actgacaaga catcacgaac tgcaaggaga cgttttggtt ggatagaacc ttctgtcaga
     1741 gcagcaccac gcgctacttg gcccccaact tcgacacgca tacgagctgt aaatggaacg
     1801 acatattcac cttcgccagt ttcaccctta acaaagactt tcttggtacg agttgatgca
     1861 tcctcttcga tagcagtaac ttgtccttta acctctgtga taaccgcttc ccctttagga
     1921 ttgcgggctt caaagatttc ttggacacga ggaagaccct gagtgatatc ggtatttgag
     1981 gcaaccccac ctgtgtggaa ggtacgcatt gtaagctgtg taccaggttc cccgatagat
     2041 tgggcagcga ttgtaccaac tgcttcacca acttcaaccg catcaccagt cgccaagttg
     2101 ataccgtaac agtgacggca gacaccgtga cgagtgttac atgtaaatac agaacggata
     2161 gtcacttctt ccacaccagc attgacaatt tcacgcgcct tgtcttctgt aatcaattca
     2221 tttggaccaa taatcactgc accagtttct ggatgtttaa cagttttctt agtgtaacga
     2281 ccgttgagac gctcttcgag agactcgatc atctcttttc cttctgcgat agaacggatc
     2341 aagagaccac ggtcagttcc acagtcgtcc tcacggatga taacgtcttg ggcaacgtcg
     2401 accaaacgac gagtcaagta acctgagtcg gctgtcttaa gggccgtatc ggtcatacct
     2461 ttacgagcac cgtgagttga gaagaacatt tccaataccg acaaaccttc gcggaagttt
     2521 gaaaggattg gcaattccat gatacgtcca ttcggagcag ccatcagacc acgcataccg
     2581 gcaagctgtg agaagtttga gatgttacca cgggctccag agtccatcat cataacgatt
     2641 gggttcttag gatcttgatt agcaatcaag cgtttctcaa gtttttcacg ggcagcacgc
     2701 cattcagctg taacagcatt gtaacgctcg tcgtctgtga tcataccacg acggaattgt
     2761 ttggtgattt gttcgacacg tttgtgtgat tcttcaatga tttcagcctt gtcatcaacg
     2821 actgggatat cggcaatacc cactgtcaat cctgcaagag ttgagtggtg gtaaccgagg
     2881 ttcttcatgc ggtcaagtag ggcagaagtt tctgtcgtac ggaaacgttt gaagatttca
     2941 gcgatgatat ttccgaggtt tttcttcttg aatggagggt tgagctcaag attgctgata
     3001 gcttccttga tatctccacc aagtggcaag aagtatttag ctggaacacc ttctgtcaag
     3061 ttggcattgt ttggttcttg caagtatggt agcccctctg gcatgatatc gttgaagaga
     3121 attttaccaa ctgttgtaag caagacctta tgtctttgct cttctgtcca aggcttgttg
     3181 aggctgtctg ttgcgatacc aacacgtgag tggaggtgaa cataaccatt gcggtaagcc
     3241 ataaccgctt cgtcacggtc tttgaagacc attccttcac cttcgcgacc agcttcttcc
     3301 atggtcaagt agtagttacc caaaaccatg tcctgagatg gagtaactac cggtttccca
     3361 tctttcgggt tcaagatgtg ctcagcagct agcatgagga tacgagcttc tgcttgtgct
     3421 tcttctgaaa gtggtacgtg gatggccatt tggtccccgt caaagtcagc attgtaggct
     3481 tcacagacaa gtgggtgcaa gcgaagagcc ttaccatcaa tcaagactgg ctcgaaggct
     3541 tggataccca aacggtgaag ggtcggtgcg cggttcaaaa gcactgggtg ttctttaatc
     3601 acttcttcaa ggatatccca gatacgctca tctccgcgtt ccaccaagcg tttagctgct
     3661 ttgacgtttt gcacgatatc acgggcaacg atttcacgca tgacaaatgg tttaaagagt
     3721 tcaatcgcca tttcacgtgg aacaccacat tggtacatct taagagttgg accaacggcg
     3781 ataacggaac gtcctgagaa gtcaacacgt ttaccgagca agttttgacg gaagcgtccc
     3841 tgtttacctt taagcatgtg gctcaatgat ttcaatggac ggctacctgg tcctgtgatt
     3901 ggacgaccac gacgaccatt gtcaatcaaa gcgtcaactg cttcttgaag catacgcttc
     3961 tcattttgaa cgatgatacc tggtgcattt aactcaagca aacgagccaa acggttgtta
     4021 cggttgataa cacggcggta aaggtcattc aagtcagatg aggcaaaacg gccaccatcc
     4081 aactgcaaca ttggacgaag atctggtggg ataaccggaa ggatgttaag aatcatccat
     4141 tcaggtttgt ttccagactt gtaaaaggca tccaaaacat ccaaacgacg gatggctttg
     4201 acacgttttt gtccagtagc tgttttcaat tcttctttga gttcagcaat ttctttttca
     4261 agatctactt gcttcaaaag gtcttggatg gcttccgcac ccatcttggc aacaaatgaa
     4321 ccataaccat attcacgcaa gcgctctcgg tattcgcgct ctgtcatgat agacttgtgc
     4381 tcaagtggtg tatccttagg atcaatcacc acataagccg caaagtagat aacttcctcg
     4441 agggcacgag ggctcatatc aagggtcaag cccatacggc ttggaatccc cttgaagtac
     4501 cagatgtgag atacaggagc tttcaattcg atatgtccca tacgctcacg acgaactttc
     4561 gtacgcgtta cttcaacccc acagcggtca caaacaattc ctctgtaacg aatgcgtttg
     4621 tacttaccac aagcacattc ccagtctttt gtaggaccaa agatcacttc atcaaagagt
     4681 ccttcacgtt ctggtttcaa ggtccgataa ttgattgttt caggtttttt gacttctcca
     4741 taagaccatg aacggacttt acttggagaa gctagggtga tttgcatact tttaaaacga
     4801 tttacatcaa ccactatttc ttccctttct attctaagtg aactgcttat tcttgttcag
     4861 cagcttcttc tgttgcttcc gcttttgttg ctttctcagc ttcttcagct tcaaaggctg
     4921 ctttagcctc ttgggctgct ttttcgcggg ctttttcaag gtcatctacg tggatgacat
     4981 cttcgtccat tccttcatcc aagtcgcgaa gttccacttc ttggtcatct tcgtctagga
     5041 cacgcatgtc aagaccaaga gattgcaatt ctttgacaag aactcggaag gattctggaa
     5101 cacctggttt tggaattggt ttgccttttg taatagcttc ataggctttc aaacgtccgt
     5161 tgatatcgtc cgacttgtaa gtcaagattt cttgaaggac atttgacgca ccgtaggctt
     5221 caagagccca aacctccatc tcaccgaaac gttgtccacc aaactgagct ttacctccga
     5281 gtggttgttg ggtaacagtt gagtaaggtc cgactgaacg cgcatgcaat ttatcgtcaa
     5341 ccatgtggtg gagtttaatc atgtacatga ctccaacaga aacacggtta tcaaatggtt
     5401 cacctgtacg tccatcgtaa aggattgtct tggcatcgct atccatacct gcttctttaa
     5461 cagttgacca aagatcttca gagcttgctc catcaaagac tggtgtcgca atgtgaatac
     5521 caagagtacg agctgccata ccaaggtgaa gctccataac ctgaccgata ttcatacgtg
     5581 atggcacccc aagtgggttc aacatgatgt cgactggagt tccgtctgga aggtaaggca
     5641 tgtcttctac aggaacgata cgagagacaa cccctttgtt tccgtgacgt ccggccattt
     5701 tatctccgac cttaatctta cgtttttgag cgatgtaaac acgaaccaac atgttaacac
     5761 ctgattgcaa ctcatctcca tttacacgtg taaagatctt aacatcacga acgacaccat
     5821 cggcaccgtg tggtacacga agagaagtat cacgcacttc acgagacttg tctccaaaga
     5881 tagcgtgcaa gagacgttct tcagctgaaa gatctttctc acccttaggt gttactttac
     5941 ctacaagaat atcaccttct ttaacctcag caccaatacg gataatcccc atttcgtcaa
     6001 ggtctttgag ggcatcttca ccaacgtttg gaatttcgcg agtgatttct tcaggcccaa
     6061 gctttgtatc gcgcgtttct gattcgtatt cttcaaggtg aacagatgtg tagacatcgt
     6121 ccttcaccaa gcgttcgctc atgataacgg catcctcgaa gttgtaacct tcccaagtca
     6181 tgtaggcaac gattgggttt tgtccaagcg ccatttctcc attttccata gaaggtccgt
     6241 cagcgatgaa atcgcctttt tcaacgacat caccaacttt tacgagagtg cgttggttgt
     6301 aagcagtacc tgagtttgaa cgacggaatt tttggatgtg gtaaacatcc aatgaaccat
     6361 cttcacgacg aacttctacc ttgtcagcat ctgcgtaagt aactttacca tcatactgag
     6421 caatcacagc cgcaccagaa tcgtgggctg cttggtattc cataccagta ccaacgtaag
     6481 gtgcctgagg attaatcaat ggcacagcct gacgttgcat attggctccc atgagggcac
     6541 ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca actacctgtt
     6601 ttggtgaaac gtccatgtag tcaacaatat tagctggata ctcttggttg accccttggt
     6661 gacgtcccat gacaatcttc tcagcaaagg ttccatcttc attcagacga gagttagcct
     6721 gagctacagt atattcatct tcttcatcag ctgtcaacca aacaatttcg ttcgtgacaa
     6781 cacctgtttc acggtcaacc ttacggtatg gtgtttgaac aaaaccatat ttgttcaagt
     6841 gtccgtaaga tgacaagtta ttgatcaaac cgatgttagg tccttcaggt gtctcgattg
     6901 gacacatacg accatagtga gtgtagtgca cgtcacgtac ttcatatccg gcacggtcac
     6961 gagtcaaacc accaggtcct aaggctgaca aacggcgttt gtgagacaac tcagaaagcg
     7021 ggttgtgttg gtccatgaac tgtgacaact gtgatgaacc aaagaattct ttaactgcag
     7081 ctgttacagg acggatattg ataatttgtt gtggtgtcaa gacttcattg tcctgaacag
     7141 acatacgttc acggacatta cgttccatac gagaaagtcc caaacgtact tggttggcaa
     7201 gcaattcacc aaccgcacgg atacgacgat ttccaaggtg gtcgatatca tctacacggc
     7261 caagtccttc agccaagttg aggaagtagc tcatctcagc aaggatatct gcaggagtca
     7321 ccgtacgaac cttgtcatct gggttagcat taccaatgat cgttacgacg cgatctggat
     7381 cagttggagc aataaccttg aatttttgaa gaacaacagg ctcagtcaca acggctgcat
     7441 cgtttgggat gtagacaatc ttgttcaagt cgccatccaa atggctttca atgctttcaa
     7501 tcacgctacg agtcataatc gtaccagctt ctaccaagat ttctccagtt tcagggtcta
     7561 ccaatggctc tgcaatggtt tggttgagca aacgtgtttt aacattgagt tttttattga
     7621 ttttgtaacg accaactgct gccaagtcat aacgacgtgg gtcaaagaag cgagctacaa
     7681 gcaagctacg tgagctttca gccgtcttag gctcacctgg acgaaggcgt tcgtaaattt
     7741 ctttcaaggc ttcgtctgta cgagagtcca ttggattctt gtggatatct ttttcaacag
     7801 tgttgcgaac caattcgctg tctccaaaga tatcaaagat ttcatcatca cctgagaaac
     7861 caagagcacg aaccaaggtt gtaaatggaa tcttacgagt acggtcgata cgagtgtagg
     7921 tgatatcttt tgagtcgctt tcaagttcca accaagctcc acggttaggg ataacagttg
     7981 aaccatagcc caccttacca tttttgtcta ctttgtcgtt aaagtaaaca cctggtgagc
     8041 ggaccaactg agaaacgata atacgttcac caccattgat gatgaaagta cccatttctg
     8101 tcatgattgg gaaatcacca aagaaaactt cttgggtctt gatttcgcct gtttctttat
     8161 tgatcaaacg gaaggttaca aaaattggtg ctgagtagct agcatcgtgg atacgagctt
     8221 cttctagcgt gtattttggt tccttgattt catatccaac aaattccaac tccattgtgt
     8281 ctgtgaagtt tgaaattggc aatacatctt caaacacttc cttaagaccg tggtctagga
     8341 aagctttgaa tgagtcagtt tgaatttcaa tcaaatttgg taagtcaaga acttctttga
     8401 ttcttgaaaa actacgacgg gtacgatgtt tcccgtattg aacgtcatgt cctgccaaga
     8461 tgattctcct ttgtaaataa gttccaagcc ttgtcaatca ggcttttcta atcgtcatat
     8521 ggttgtaaac cccttatcac cgtgtcctct tgacgaattt tcagaatctt taagcctctg
     8581 ttacaaatgc tcataatctt gaaaaaaagc acaaaaagag cagctaaatc tgactttttc
     8641 agaagattta actgctgtga gccttgtctg gacaatattt cagacaaaac ctacgacaaa
     8701 tgattaccca tattataccc tatttagcta gatttttcaa ggggtttcag taggtttttg
     8761 gtaaattttt tcccatagaa aacttggcat cacattcgaa tcacgctatg gtacaaaaaa
     8821 ctgaaaaaac tattgactga aaatcatttt caaggtataa taataaacgt taaggcggta
     8881 tagccaagtg gtaaggcacg gctctgcaaa agcttgatcg tcggttcaaa tccgtctacc
     8941 gccttctata acttgattta tcaggtttca aatgaacaga aagcccaatt tgaagggctt
     9001 tttttatttt ccctcgaata aatacgtata actttaaaaa cttttggagc gagtttgtgg
     9061 cagagttctt tccatggcat aattcccttt tgaaatcaat tgaaaaaagc ttcgtcacgc
     9121 ctggtgacaa aagcctctag tttattctgt ttcttcttct atttcgactt ctgtgatttg
     9181 gacttttacc ttggtaacac gtccattctt cactttatca ttggttaaga taaactgttt
     9241 gttttggctg accaattcat agctgagttt ctcagtcgtt ggaatggttc ccactcctgt
     9301 caaataataa ccagcgatgg tatcaacgtc atcactttcc agctcaacat caaagtaatt
     9361 attgaaatca ttgagggtca tagttccttg aacaatgtag gtatcctcgc caatctgatg
     9421 aacatctatt gctgctttgt ccgtttcatc atcaatttca ccaacaattt cctctaagag
     9481 gtcttccaaa gtcactaaac cagccatacc accgtattca tccagcaaga ttgccatttg
     9541 tctttgggta tttcgcagtt cttttagcaa gtcatccaca aaaatagttt caggtacaaa
     9601 aagtggatct tgtaaaattc tcttccaaac aatattgtca aaaccgtcca caaagcctgc
     9661 cttaaggaga ctcttggtgt gaatgattcc aattacattg tccttatccc catcataaac
     9721 cgggatacga gaataatttt gttttaaaat actttggata atggcttgac tatcatcctg
     9781 aatatccacc ataaaggcat ccgttcgagg aaccataacc tctcgtgcca tcagttcatc
     9841 gagcgaaaag acaccttgta gcatctcaat ctcatcagca tccaatgttt cttcactatt
     9901 tgtcagcata taggcaattt catcacgggt cattttttca tccgcatcat cgaatgacat
     9961 aggagtcaaa tggctcaaga aattggtcga agcagctaaa agccaaacaa aaggactgac
    10021 tagttttccg atcccaatga taaccggcgc tgtacgaatt gccaaggcat cctttagatt
    10081 aagagcgatt ctcttaggat ataattcccc aaaaacgatg gaaatatagg tcaaaaatgc
    10141 caaggataga aaagttgcca cggcttgtgc tgtttcgcca ttcccaagcc aagaggcaat
    10201 cacacgtcct agagtatcag ttaaactcgc ccctgataag attgtaatca gggtgattcc
    10261 tacctgaatg gttgataaaa agtggttagg attttctagt accttcagca ggcggatgta
    10321 gcgtctgtct ccttcttccg ccttttgttc aactcgggca cgattaagag aaaccatggc
    10381 catttctgtg gctgagaaaa aggcatttaa taccgtcaag ataaacaata aaacaaattg
    10441 tagcaacaaa ttctgactac ttgggtcttc catagttctt ctcctaaaat agtatcttat
    10501 cctttattat atcacaaaat ttaatccaat acatattatt tttttcttag cgtaacttcc
    10561 atctctctcc caaaactgga agttagtcta agacggattt ccactgattt cacgcgtttt
    10621 tctcatacta aaagctaggt tgtgggaaac tggaagttag ttttagaagt tactattttt
    10681 tcttagtacc tattctagcc ctgcttaaac tagtaaaaag aactcctaca tccataagtg
    10741 acataggagt ttaggcttat cttttactga gttacagtta cttctccagt tcggtaatcc
    10801 agttgaagtc ccttttgaac attgggaact agaacattga attccaattc tccatccgaa
    10861 gacttggctt caatctgtga agctgaggga actaaatcct cgtttgaagc gtagtaaagg
    10921 gttacacggt aacggacacg cttgttttgg tccaaggctt tacgcacctt gctttcatag
    10981 tagttttgac cagtcgaata ctcggcttgt gcctgatttg cccaggctgt ctgaacagca
    11041 atgtttttag gattgcttgt tgaggcatca aaaccatcca aaccaccgat taaggcatag
    11101 cctaacaaat gacctctatc gactgcatgg gtataagagc cctttagatt cttgacctga
    11161 tgccaacctg gaggagtcca agaagttgaa ccattcccag tttctttacg attcttgtac
    11221 tgacgagtgg ccttagacaa gagggcatta gctacggttg gaacagtttc cttgcccact
    11281 gtctttgttt tattgtcagc gtagggctta cttgaaacct tggcatctag atttgtttta
    11341 ttaccattga cgataaaagc acctgagcca ttccactcca gactcccctt tatttgactc
    11401 ttgactgcgt ctgttaagac actctctgcc aatgcttgac taggagcttc agacgcttgt
    11461 tttttctgac taagattggt tttgggacta ttaggtgccg actgcatctg cttgatataa
    11521 tagctccctg tagacaaaag caataacact agcagtccga ttagtgtctg tcttgttttt
    11581 ttgttcatat ttctccttat ctttagaaaa aggctggttc tccagcctaa tttcctgtaa
    11641 atttatgaat caattcctgc cattttgctg gagacaggat agcccatgga tcttgaccct
    11701 tgcccaagat tccataacct accattagac cgattcctag agccagagta cctaaaatca
    11761 gtactatgat gactaaaagt aaacgattga ttacgtagct tgatttctta ttcatcttca
    11821 tcgcttgcct caatccgctg aatcttagca cctagctgcg ccaacttctc atggaaaccg
    11881 tagtaacctc tatccaagtg aaccaattta ccgaccacag tttctccctg tgctaccaaa
    11941 cctgtcaaaa tcaaggctgc actggcacga aggtcagttg aaagaacttc tgctccctgc
    12001 aaaggctgtc caccaacaat acgagctgta tcacggataa tctcagaatg caagcccatg
    12061 cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa ctgtctccac catggttgat
    12121 tcgccttttg caactgtcat caaggctgta aattgagcct gcatatctgt tggaaatcct
    12181 gggtggggca aggttttcac atgaacagct tttagatttt ctagttgaga acgaacacga
    12241 attccttcgt cttcttcaat tacttcaaca cccatttcaa gtaacttggc aatcaaggga
    12301 cggttgtgct cccagacagc gtctcgaatc aagacatcac caccagtcat ggcagcagct
    12361 accataaagg ttcctgcttc gatacggtct tggactacat tgtgagtcgt accatgaagt
    12421 ttctcaacac cagtaatggt tatagtctct gtaccagcac ctttgacctt ggctcccatt
    12481 tcattaagga gaatggctaa gtcaacaatc tcaggctcac gcgcagcatt ctcaatcact
    12541 gtcaccccat cagccagagt cgctgccatc atcaagttct gcgttgcacc aacacttgga
    12601 aagtccatat agatatgagc accatgcaag cgttctgcct tggcttcgat gtaaccagct
    12661 gtctgactaa tcttaacccc catagcttcc agacctttca aatgaagatc aataggacgg
    12721 ctaccaatcg tacaaccacc tggcatggat accttggcat gacccacacg ggcaaggatt
    12781 ggccctaata caacgatgga ggcgcgcatc ttgctgacat acttgtaagg ggcttcctca
    12841 gtgatgtcgc cagtagcatc caccttgaca agatgagctt cctcatcaaa gtcaaccttg
    12901 gcattcaaac caccaactac ctgattcata ataaagacat ccgacaaaat cggaacattc
    12961 tgcaagacgg tctttccttc acttgctaga atagtcgctg ccaacaaggg taagactgca
    13021 ttttttgctc cctcgatcgt cacgcttcct accagacgat tatcgccacc ttgaaccaca
    13081 attttatcca tactcgtttc ctttactctt gatttcataa taatcctcta agcgcttctt
    13141 gccacaaatg atacaggcta ataaagaaag aactcaggat gtagcctatg acaatgctaa
    13201 aaaaggctac taataaacga acttttcttg tattctcatc tgtcactttt aaaaccttct
    13261 cccatctaac aagatccttt aaaaggtaaa aactcacata aataaagagc atatgactac
    13321 ttagagtgaa taataattga accatttgac tattatacca tcttctctgt ttgtgcgcta
    13381 gtttggaaac ttcactcaaa aattagggat tgtttttcaa gtaatcaatc gcatcttgta
    13441 gggttttaac gggcacgatt ttcatatccg tcttgattgt tttagccgct tctagggctg
    13501 tttggtagtt gtttttcgcg tccggatgcg ccttttgttc ttcttcgcta acagggttat
    13561 caggagcaaa gaaaatagca gcacctgccc tagccgaagc tacaaccttc ttatcaatac
    13621 ctccaatgtc tcccacatta ccatcgcggt caatggtacc tgtaccggca acaatacgac
    13681 cattacgaag atctgggtga gctatttgag tatagatagc tagactaaac atgagaccag
    13741 cacttggacc gccaatacca gctgttgaaa agctaattgg gacattgctg attacctctg
    13801 tacggtcaat caagccgatt ccaattccat ttttgccatt ttccaaggtg ataatctttc
    13861 cttctgcaga cttggtttgc ccatcctctt cataggtgac cttgacggaa tcccctaatt
    13921 tttgagaact gacgtaatca atcaagtctt tggaactatc aaaggtctga tcattgactg
    13981 ctgtgactgt atcagagata ttgagaatcc ctttaaaggt tgaattatcc gtcacattca
    14041 aaacataaac tccaaagtac ttgagttcga tatccttacc agctgttttt agtccttgat
    14101 acttggccat attttgcgat gtttgcatgt agaattgatt gattcgcata aattcaacat
    14161 cggaagaacc acctgtagtc tcctgagcac tacgaatatc tgtaaaaggt gtcaaccaag
    14221 cataaatcat atgagctaaa gtggcatgtt gaacaccaac cgtaacgaat tgataggcac
    14281 cagcttcctt atcttctgtg tcatttattt taaggacttg gcgaatatct tccgaaccac
    14341 ctggaacctc tatataataa ggcaagggca ctacaaatgc caagaaagtc acaatcaagg
    14401 ccgcaatgac gtataagggc catctaatct tttttttcat ttcttatttc ctccaaaata
    14461 ctctcgggaa catagcaggc aatatcctga ccaaacttca aaagctctct aacgcctgat
    14521 gaactgatat agagatgttc aggtcgacta tgtaaataaa tagtctctat atcagaagac
    14581 agctgatgat tgtagtaatc aaaactggct tcatattgca aatccgacgc attcctcaaa
    14641 ccacgcacta gacaagtagc acccaatctt tttgcaacat cgaccaccaa ttcatcatga
    14701 gaagccacga cttcaacatt ttccagatgt cccaaagcct tttctagccc ccgtttacga
    14761 ttttcgatag gaagaaatcc ttgtttgtgg ggattaaaaa aaataccgac atagagctta
    14821 tcaaagagtc tgctcgcccg ttcaatgata tccagatgcc catttgtcat cggatcaaat
    14881 gagcctgtga ataagccaat cttatctgac atagactgtc accttactaa ttccataaat
    14941 cttttccttc cagataccca gacaggcaat ttcttctgga agttcaacgg ccttatccgt
    15001 ctcgcacaca accataacat cttcagaaaa aagctctctc tcagccattt tttcaatatc
    15061 tgctacgatt tgttccttgg tatagggagg gtctaagaaa acgaggtcaa attccccaga
    15121 tacctgttcc aatgcccttt ctgcatccat cttgaggagt tgaaattttc caatttcctt
    15181 ggttatctgg atattttcag ccacgatggt ctgagcctta cggtctcgct ccaccaaaac
    15241 agcactggac atgccacgcg atactgcttc gatagataaa ccaccactac ctgcataaag
    15301 gtccaagact cgtccccctt caaagtaggg accaatcatg ttaaaaatgg ctcccctaac
    15361 cttatccgaa gtaggtcttg tcgtcttgcc ttctagtgtc ttgaggggac gtcccccata
    15421 gattcctgat acgattttca tactgtttat tataccaaat tatagacaaa aagagaaaga
    15481 aaaccgaacc ttgcggttcg attctctaca aaatattttc gtaagtatcg cggacttctt
    15541 gaggccaaac acttgtttgc acttctccga tgtgtctctt gcgaagtagg aacatggcca
    15601 tacgagattg tccaattcct ccaccgattg tcaatgggaa tagaccattc aacaaagact
    15661 tgtgccattc caattccaag cggtcttcat cacctgtaat ttccacctga cgtctaagag
    15721 tttcttcatc tacacgaatt cccatagaag acaactcaaa ggctccacct aaagactcat
    15781 tccagacaag aatatcacca tttagaccct tgtagccatt ctcagactcg cttgtccagt
    15841 catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc tggcaactcg ccaccgatac
    15901 caatcaaaaa gacggctcca aattctttac aaatcgcatt ttcacgttct ttcggtgtca
    15961 agtctgggta gcgttctacc aattcttctg tatggataaa ggtgatttgt tttggcaaga
    16021 tagactcgat gtcatagcgg gcttcaacag ctagctcagt caggcgaata gccttataaa
    16081 tcttctcaac tgtttctttt agataaacga tgttacgctt accatttggg ataaccttct
    16141 cccagtccca ctggtcaaca taaacagagt gggttgcatc caaggaatcc tcatctggac
    16201 gaagggcttt catgtggaca aagagaccct ctccttcacc aaagccaaaa cgagccaagg
    16261 tgtggcgttt ccatttagca agtgagtgca ccacttcata agtagcatca gggatttgga
    16321 gaaccttgac cgatactgga ttttccacac cagacaggtt gtcctgcatt ccgtcaccga
    16381 ccttactcaa gataggacct tgaacttcga caacttctag cttatctttc aaatactggg
    16441 taaaagtgtt tttgacaaag gaaatttctt cttgttgatg gataaaactt ttcttcatag
    16501 acaactcctc aaaaatttaa taaacgtatt atacacctat ttccaagaaa agaaaagaga
    16561 aaatttaaaa aaatcagtgt cactcaaaac actgatttca tagacctttt agtcattgcg
    16621 accaaagata cgtagaatac ttaggaaaag attgataaaa tcaagataga tgctgagagc
    16681 cattgacacc acccaacctg tcgctacacg accttgtgat tgttcatagg cgaggcgaat
    16741 cttttggtta tcccaagcaa tcaaccctga aaaaaccaaa accatggcta cgctaatcat
    16801 ataatcaaag aagccactag ccaagaaaat attgactacc atagcaatca gtaaaccaat
    16861 gagagctgcc atcattgctc gaccaatccc actcaagtct ttcttggtaa agataccaac
    16921 tgccgccatg acaaagaaga gaagggcgct cgatacaaag gcagataaaa ctgtacccgg
    16981 agtatagaaa gccaccacaa aactaagggt aaagccgttt aaaacggagt aaagtaaaaa
    17041 tactggaaga gcagctggac tatttcttga agccatgcta ctggcaacga aaaccaaagc
    17101 caactccgca aaagtagcaa tggtcaacca gagacgcccc tgcatcaaaa agtaaaccaa
    17161 ctgagactga aagaccgtca acataaggcc tgataccaaa gcagatagtc cgattcccag
    17221 accaacaaag gcataaacct tagcgtaaaa ttgattgaga cctgcacggt catgtataat
    17281 agtgtgattc atccatttct ccttttctgt gaacatcttt ccttgattat aacaaaaaaa
    17341 gttaaaatta gcttaaatgg aagattaaaa taccggctgc aaccgcaaca ttcaaactct
    17401 cggcctgccc cttcatgcta atatggacca actggtctgc actttcagcc ataaggggac
    17461 taattccttg accctcattt cccataacta gtacaaaatt ttctatagaa ggcagttctc
    17521 tgtaatcaac agaatcttta gatagggttg ttgctagcac tgggatagct acctttttag
    17581 tttcgtcaag aagcgcttga ctagtcatcc ggtaaatggg cagatggaaa tgactacctt
    17641 gcatggaacg tagggttttg agactgtaga tgtctgccga cttatctgaa acaatcactc
    17701 ctgtaaaacc tgctgcatcc gcagttcgaa tgatagttcc tacattacca ggatcttgca
    17761 catcttccaa aaacaagaac ttgccctgac tcaaatcagc ttgtcctact tcttctcttt
    17821 gaaccacggc aacaattccc tgtggagtct gagaatccgc caaatctagc aaaatatcct
    17881 ctgacaccca gacagtttgc gaaaaagtag ctaactgatc tcgataattt tctagggtaa
    17941 agattttctc aatcgtcact ccagcttgaa cagcttcttc aaacaagtgc cagccttcaa
    18001 tcaaataggc tgacttgcgg tatttttttt ggtgtaattt cttggtattt tttaccacag
    18061 aattggcttt tgaggttata atagtcatag aaatattata acacaatcaa aggggtttgg
    18121 tatgcaaaag gttagaatga ttgcccaagg tagggtacag ggagtcggct ttcgttgggg
    18181 tgtttacagc ttggcccttg aaatcggtgg catcacaggt cgggtatgga ataacgacga
    18241 tggcacagtg gaaatcttag cccaagcaga ctcatctgct atcatggcaa aatttatcca
    18301 agaaatccga aaaggaccga cacctttttc aaaagtaagc tacttagatg tcaaactaag
    18361 caactttcct ccctactctg actttaaaat cgcaaattag gtctccagaa ctattgtata
    18421 ttttgtaaaa aaacagtaga atagaaaggt ataattttta aagaaggaat aaaaacagtg
    18481 aaatctatta aacgttttgc attctcggct atgggagtgg ctatgttgct tgtcttgact
    18541 ggctgtgtca atgtcgataa aaccacaggt cagccaacag gatttatttg gaatacgatc
    18601 ggagcgccta tggctgaagc catcaagtac ttcgctactg ataaaggtct aggctttggt
    18661 gtcgctatca ttatcgtaac cattatcgta cgcttgatta tcttaccact tggtatctac
    18721 caatcatgga aggcaacgct tcactctgaa aagatgaacg ctctcaagca tgtccttgag
    18781 ccacaccaaa cacgtctcaa agaagcaact actcaagaag aaaaactcga agcccaacaa
    18841 gccctctttg ccgctcaaaa agagcacggc atcagcatgt ttggtggtgt aggatgtttc
    18901 cctatcctcc ttcaaatgcc tttcttctct gctatctact ttgctgccca acatactgaa
    18961 ggggttgctc aagcaagcta cctaggcatt cctctaggtt ctccaagtat gattttggtt
    19021 gcctgtgctg gtgtccttta ctatcttcaa tcgctccttt cacttcacgg ggtagaagat
    19081 gaaatgcaaa gagaacaaat caagaaaatg atttacatga gcccactcat gatcgtcgtc
    19141 ttctccctct tctcaccagc cagtgttaca ctttactggg ttgtcggtgg tttcatgatg
    19201 attctccaac agtttatcgt caactatatc gttcgtccaa aacttcgcaa aaaagtccgt
    19261 gaagaactag ccaagaaccc accaaaagca agtgctttct ctaaaccaag tggacgaaaa
    19321 gacgttaccc ctgaacaacc aactgctatc acaagcaaga aaaaacacaa aaatcgcaac
    19381 gctggaaaac aacgttcgag ataagaagaa aaaggcttag ctgatttgct aagtcttttt
    19441 gcaaatcaaa agcccgatgt ttccatcagg cttcttttct atccatgtac acgtttcata
    19501 taatcttgat aactttcggt atccatgagt tttttagcgt tcttgacgcg atctgctgtt
    19561 ggtggtttga ctccttcgag ggaatatgga attccaagtt cacgccactt gaactcaccc
    19621 atggtgtgat aaggtagaat ttcaaactta tcaacatttt tgagggtctt gacgaactta
    19681 ccaagttcaa tcaagtcatc atctctgtct gtcaatcctg gaactagcac gtggcgaatc
    19741 cagacaggtt ttccaatatc tgatagatac tgggcacaag ccaagatatt tttattagtt
    19801 tgtctagtga caatcttgtg ctgttcttcg ttgatttcct tgatatccaa aagaaccaag
    19861 tcagtgacag ccatgagttt gtcaaacttc tcaaggtaac gtggtttatt acggaaagga
    19921 agagcacagg tatccaaggt acagtggatt ccttgttcct tagccttggt gaagagagca
    19981 atcaggaaat caatctgcaa gagagcttct cctccactga ctgtaatccc acccttattt
    20041 ccccagaaac cacggtagcg caaggcctct gtcaagacat catctaccgt ccgttcacgt
    20101 gacttattgg actccatagc ccaagtgtct gggttgtggc aatactggca acgcatgtga
    20161 cagccctgca aaaagacaat aaagcgaata ccaggcccat ctactgaccc aaagctttct
    20221 gtcgaatgca ccattcctgt cacttgtcca taatcaattg tttcttcaga catatcgtta
    20281 ccttccttga aaacgtttta tagttttatt atatcatgac ttgaaggaaa aacaagattt
    20341 ttgcctattt tttagaaagc aatctgtttt tcaatttcat tttcaatcta ttatcagatt
    20401 attcttcaaa atcgaagcca tataaggttg caaaatagtc ctcagggcgc tctgcacggc
    20461 ggatttgacg ggctttacct tcttcggtat agaggatttc cgcagaacgt aatttggcat
    20521 tatactggta gcccattgaa aatccgtggg cacctgtatc atgaatgacc agcaaatcac
    20581 cgatttctgt atgaggcagt tcgcgattga ctgcaaattt atcattgttt tcacagagtg
    20641 aaccaaccac atctaccgct tcagctggtc catctggatg ggtcacgttg ctaatatgat
    20701 ggtaagctcc gtacatagct ggacgcatga ggttgactgc tgaggcatcc acacctagat
    20761 aggtacggta ggtttccttc ttatgagtca ctcttgtgac tagagcaccg tgaggtgcca
    20821 gcataaaacg acccaattcg gtgaaaatct tgacctgacc aagacctgct gacgtaagaa
    20881 cttcttcata caccttacga actccctcac caatcaaggc gatatcgttc ggctcctggt
    20941 ctggacgata attaacacca ataccgccag aaagattgat aaagtctagc gaaatgccca
    21001 acttttcctt gatttcaaca gccagttcaa agagctgacg agccaactct ggataataga
    21061 gatgggtcac ggtattggac gctaggaagg agtgaatccc aaaagtcttg gctccttttt
    21121 ccttcaagat agcaaaggct tcaaagagct ggtccttggt catgccaaac ttagcctccc
    21181 caggattgtc cataatgtct gtccccagtt caaaaacgcc tccaggatta taacgacaag
    21241 agatgatttc tggaatgcct gctactctct ccagatgttc aatatcttca aaggcatcca
    21301 agttaatggt cgcacccaat tcacgtgcat aggcgtattc cttgtctggc gtgttgttgg
    21361 aagagaacat aatctcagaa cccagaaagt ccagtttatg gctcatcaaa agctctacat
    21421 aactagagca gtccacacca caaccttctt cttggagaat tttcaaaata gctggagttg
    21481 gagtagcctt aactgcaaaa tattccttaa agcccttgtt ccacgaaaaa gcttggttga
    21541 cggctcttgc cttctcacga atccccttct catcatacaa gtgaaaggga gtcgggaact
    21601 cggcaacaat cgcttctaac tcttctctat tgataaatgg tgttttcata agcttccttc
    21661 tattctgttt gcaaagaaag gctgggacaa tcgttccaac ctttagttct atctcttatt
    21721 tatcttcgtc aaagatattg ccaacctcaa catcgatggc ttggttcttg acatcaatat
    21781 tagttacctt caagagtgac ttgtagtcaa actgcttttc acgttcttct tgggcattgt
    21841 ccgcaaagac cgctacacct gccagttctg agtcgaactc gcgcaagaga ctaatcatac
    21901 cgttgaccgt tccgccacct ttcaagaagt catccacaat caagacacgg ctgcctgcct
    21961 taagactacg ttttgaaagg aacattttct cgatacggtc accacttgaa cctgaaacat
    22021 agttgacgct aacagttgaa ccttcggtaa ttttcaggtc acggcgcaca atgacaaaag
    22081 agacattgag gacattggca actgcatttg caagtggcac acccttagtt gctacggtca
    22141 taaccgcgtc aattttttgg tccataaagc ttttggcaat aatacgacca atatttttca
    22201 agatggctgg tgtgctaagc aaatcagaca gatagatata accacctggc aagatacggt
    22261 cactttctga caacttggta cgcaagtctt caaccatttc cttagcatcc tgactcgaaa
    22321 tagacggtgt gaagatgaca cctccgccag ccccagtcac tgtctggata tgaccgattt
    22381 caatttcctc aaaggcgcgt ttgataatga cgatatcttc tgagatggat gatttagcag
    22441 actcatactt ttcagcaaaa gtattgagac tagttagttt ataaggatta ttaatcaaat
    22501 agttggaaat gacaaccatc cgatcacttc ttcttaattt catttctatt tcctattcca
    22561 tttttattca aaaaatcaaa aagcaaacta gaaagctggt cgctggtggt tcaaaacact
    22621 gttttgagat tgtcgataga actgacaaac cctgtaatat acctgcatat atacatacga
    22681 caaagcgata ctaccctagt ttgaagatat tttcgaagag tattcatttt tgtcttttac
    22741 ttattatacc atattcacat aaaaaaacga acattcttat cctaaaaaat gctcattttt
    22801 cttaaattat caatctaaat ctggtttata gaaggaacga ttatccatag cgaagatttt
    22861 attggtcatc tctcctttat ccaccaaagc cagagctgtt gacatcatca tcatgcttgc
    22921 atccagattg tcaatcatat ggataatctc tgcctccata atacgtggac ggactggact
    22981 tccatattca agcaagccgt ggtgactgag gatgacatga cgaagcaaaa cgacttcttc
    23041 cttggtatca tcgatgccga gttccataac tgtcttggta atttcgctat caatgagagc
    23101 gatatgtcca agaagattac ctcgcactgt gtactctgtc tggtctggcc ccgtcaactc
    23161 gatgacctta gccaagtcgt gcaacataat ccccgcatag agcagactct tattgagctg
    23221 aggataaact tcgctaatag cgtctgccaa acgtaccatg gtcgccgtat gataagccaa
    23281 ccccgtttca aaggcatggt ggttggtctt ggcagctgga taggagtaga attccttatc
    23341 atacttggtg tagagatttc ggacaatccg ttgccagaca ggattttcaa ttttgaaaat
    23401 catttgcgac atgtagtcac gaatttcctt gacatcaact ggtgacttga ccttgaaatc
    23461 ggctgggtca ttgggttcac cagcttgagg caggcggaga gtaatttgat tgacttgagg
    23521 ggtattgtta taaacttctc ggcgtccttt catgtggaca accttacctg cggtaaaggc
    23581 ctcaatgtta tgaggttggg catcccagag cttcccatca atctcgccac tatcatcttg
    23641 gaaggtaaag gctaggtagt ttttcccagc tcgagtttgc ctcaggtcag ctgatttgat
    23701 taggtaaaag ccttcaaata gctcatcttt tttcatgtga ctaatcttca tattcttcct
    23761 cattttcttg aaaatggagt agatcaagcg caggctcgcc ttctgacaac tcaatgtgac
    23821 ggagcgtccg ctcgatagct atggtacgac ggtttaataa ttcatcaata ttgccagagg
    23881 catgttggag atgtttttgt gccttgacca gaataccacc aaacttgcca aactcggtct
    23941 tgacactggc aagagtcttg ctgatatggt cggcactctt ttggatatta agggtcttga
    24001 aaccaactga tagggagtta agaagggctg atagggtact tggtcctgca acaataatct
    24061 gttcttcccg tctcaaatca tcaaagaaga ccggattgcg gacgatttct gagtagagac
    24121 cttctgtcgg aacaaacaaa actccaaaat tggtcgtccg aggtggtgct atgtacttgt
    24181 tcctaatatc cctagcaaaa cgcttgacac ttgctaggag tgacttacga cagcgttcga
    24241 tttcatcctt gtcacctact tcataggctt cttctaagcg gtaataatct gccagtggaa
    24301 acttagagtc aattggtagg tagacgtatt cttggtcgcc ttgtccgggt aacttgatgg
    24361 catactccac tcgttcacta gagttttcaa ccgttgcgta ttctcgttcg tactgggcag
    24421 gtgtcatgat gtcttcaata atttgcccca gttgcaattc tcccagaatc cctcgcgtct
    24481 tggttccaga gagaaccttg ttaagagctc cgacatcacg ggcaactgtc tgcatttctc
    24541 caagaccacg attgacagac tccagttgtt tagaaactgt ctcaaaggaa gcctgtaagc
    24601 gtgtctgcaa ggtcttttct agtttttcct cgaccgtctg gcgcatttgt tccaaacgtt
    24661 gctcatttga ttcctgcaag gcttggagac gttggtctgt cttgtctcta gtttggagga
    24721 gattatctgt catttcttga cggacttggg tcaggccttg gtgcaattca atccgcactt
    24781 cttgcaaacg gtcgctgaca gccacttcca aatctttttg gtctaactgg ctggcttgtc
    24841 tggcttggtc aaagcggtaa tccaactggt ctgacaaatg atctgcctga tcctccaagc
    24901 tcttacttaa gtgtttctcc tgcctatcct gtctttgcca aatcagaaag agaccagcta
    24961 ggttggcaat taataataga ataagtaaac tttccatcct acctcctgtc cttgctatgc
    25021 agtacgacca cataaccatc tgggcaagtc accgacactt ccctatctat atattcgtta
    25081 gaagcgtaca cttttttaaa gaaaaaattc tcctctgtca actcatactt agctccaaga
    25141 atagtcagct ggctatcccg aactggcata aaggctagat agtcgtagtc tgaacgaggt
    25201 tctagctgac tggtcccttc tgaacaatag gcaatcaaat tttgcccatc ctcaatttct
    25261 atttgacgca tatagggtgc caacttagga ttgctaggta gaaagacatt ggccaacata
    25321 tggtcaatac ggccacccaa ggcaccgaaa atagtgacct cagcctgagg attttgttca
    25381 aagatggtta agagagccaa ttccagatct gtatcatcct tttctggtcg ggcttggaca
    25441 aaatgctggg cacgtttttg aatcacctgt cgctcttctt ccgtcacaga atcaaaatcc
    25501 ccaactgcta gagcaagaag caagtcttct tccaagaccc agagcgagcc tcgatccacc
    25561 ccaacaaaag catcaaaatc tgtccgataa tgaccgcggt ctccgcctgc aaaaacggca
    25621 accctagtcc agttgttttc tgagagtttg tactcgctca ttgacatctc ccttaaagac
    25681 ataggaacct gctacaaaaa cggtcgcacc agcttcttta gcttgggcaa tagtttggtc
    25741 atcaatccca ccatccactt cgatttcaaa gttcaaacct ttttcctcac gaagagcaac
    25801 caactcacga accttatcca tggtttctgg cagaaaggct tgcccaccaa aacctggatt
    25861 aaccgtcatg actaaaactt ggtcaactag atgaaggacg tgcttgatgg cttcaactga
    25921 tgtgccagga ttgataacga ctgaaggctt aactccgagt gaacgaattt tttggagggc
    25981 gccatgaata tgaggcgttg cttctacatg gatactgatg atgtctgcac ctgcacgcgc
    26041 aaaatcttcc agatgatgct cagggtttga caccatcaag tggcaatcga aaaccatctt
    26101 actatgagga cgaaggctct cgaccacacc tgcaccaaaa ctgatttgcg gtacaaaatg
    26161 actgtccatg atatcgatat gggcatattc tgccccagtt gcttctagac gtttgatttc
    26221 acgttcaaag ttggcataat ctgctgccag aattgacgga gcaatcttgt attgagacat
    26281 aggtttctcc ttattttgga atttttttgc tgactttttt ataggtttct ctacgatttt
    26341 caatttcact aaggaattgc aggtaattgt caaaacggaa ggttgcaata acaccctctt
    26401 caacagctgg tttgacggca caagacggct catgggtatg ggtacaagta cggaacttac
    26461 aatctcggct aacagtagca atctctggga aagcctgatt gaggtcttca gcccttgata
    26521 cttcatagtc caaggatgaa aatcctggtg tatctgcgat tttacccccg ttgagattgt
    26581 aaaaactaac agctcgagtg gtatggcgac cgcgacctag actgtctgaa atttctcccg
    26641 tttcaagatt gaggtctggt gcgattttat tgagaagagt tgacttccca acacctgtct
    26701 gccccataaa gaccgtaacc ttgcctgtta acaaagacag gagttcctct ttactggtca
    26761 caaagtcata gccgatgtca ccataggtct gctggtaaaa atccagttct cccctatctt
    26821 ccaacaaatc cattttggaa atatagacaa tgggatggat gcccttgtgc tccaaaagaa
    26881 ccaagaaacg atccagcaaa ttgctgttaa aatcaggttc cttgacggac atgattacta
    26941 cagcttgatc gatattgaca ataggcggac gaaccagact gtttttccgt tcgtgaattt
    27001 tgaggatata gccttctgaa ttttcctcgg cagagaaatc tacccagtcc ccaacataag
    27061 gggtatggcc ttttttacgg aaattcccac gcgcgcgtgt ttgataaacc tggccatcac
    27121 tctccacata gtagaaacct gccaaggctt taatgatttg tccctgcatc ttagagtcct
    27181 tgccctttaa gtgcgtctgc tagaccggca aattctgcca agctgagagc ttccccacgc
    27241 acacttggtg acaagcctgc ctggtccaaa gccttggtca gcttgtcctt gacctcttca
    27301 gtcttaccaa agtaacctgt caagttattc cacaaggtct tgcggcgatg ggtaaaacta
    27361 gccttggaaa ccttaaagaa aaagttctca tcttctactg ctacggctgg ctctggacga
    27421 cgcaccattt tcaagatggc tgaatccaca tttggcgctg gcacaaagac cgtacgaggc
    27481 acgataaagg caaccttggc tgtcatgtaa tactgcacgg cgatagacaa gctaccgtaa
    27541 gccttggtgt taggctgggc tgaaatgcgg tccgctactt ctttctgcat catgaccaca
    27601 aactcactaa aaggaatgcc actctcaatc aagtgcatga gaataggcgt cgtgatgtag
    27661 taaggcaaat tagccactac cttgattggc aggttaggat ttttaaaatt ttggatatgt
    27721 tgcgccaaat caaccttgag aatatcttcg ttaactacag tcacattatc aaaatcacgc
    27781 agggtatcta ccaaaattgg caccaaacgg tggtcaatct caaaagccat gacttgggct
    27841 gcacgctcag ccagaaactc cgtcaaggca ccaatacctg gcccgatttc gatgacattg
    27901 acctggtcat caatttcagc cgtatccaca attttttgaa ggatattggt atccgtcagg
    27961 aaattttgcc cgaaggactt tttaaaggta aaaccgtgac gctccagcac tgccttggtc
    28021 acgctataat ctgcaattct catctattct cttttctatt atctgttact actattgtaa
    28081 cacattcccc ttgtattttg ggaatgaaaa tcataccaaa aaactatctt tcctcatgaa
    28141 gaaagatagt cttggaaatc tttaaaagtg gccttaacag ttctctcgaa acatgcgttc
    28201 atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgtcgtact caagtacagc
    28261 ctgcggctag cttcctagtt tgctctttga ttttcattga gtatcaaaaa aatcagcttc
    28321 ttgataactt ctattttcgg gtagggtcaa atccacatcc tcctccacat catccactgt
    28381 cagttcaacc gtttgaggta aatttttcaa acgataatgc ttttgccttt acccttcaat
    28441 actagcaaaa tcaagcaaat agccatgcac taggatttga accaaaagga gatgattggt
    28501 catattttta tcttctaaac cacctctggc actaggataa tcagataccc tgcgaatacg
    28561 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    28621 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    28681 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    28741 tcaagggtgg atttttcaaa atagtttttg caagggcaac tcgttgggcc tctcccccag
    28801 ataaagtata gattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    28861 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    28921 aattttcttt gattgattgg ttttctaaga ggccgaaatt ttgaaagaga tagcccatct
    28981 ggtctcgaaa atactcacga gtaggaatgg tttttaaatc tttcccctga tagagaaccc
    29041 ttccaccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    29101 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    29161 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    29221 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    29281 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    29341 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    29401 agttcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    29461 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    29521 ccaataagga gagagtaaaa ctccacccgt ttgtcattta gtaccttggc aaaaaatagc
    29581 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    29641 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    29701 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    29761 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    29821 aaagctagcc ttacctgtgg gaggtagtgt ttctgactcg tcacttctac actttcagat
    29881 gaaaagtttt gcaggtaatc tgtaaacaat ccttggtagt agacagactg ctctcgcaag
    29941 ctctcaggca agatcagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    30001 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    30061 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccatctgag
    30121 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    30181 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    30241 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    30301 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    30361 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    30421 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    30481 gtagaaatcc ctgccaaggt caatccataa agtagaagag caatgatgac cagttgcacc
    30541 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    30601 agcactgagc agataagctg tctcacatct tctaacactg gtctgagagc aactccaaac
    30661 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    30721 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    30781 gccgtcaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgataa
    30841 ccaagctctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    30901 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    30961 ggaagctttc cctcaccata agtggcatag gtaaagcgtg tttctccagc ttcatttggc
    31021 tcaacgattc gacgagcaat gagactattg tgctctaccg ccaagtgact caaagcctct
    31081 gtcacctctt cccgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    31141 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    31201 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    31261 cttggtcact tagtgagaag gtgaccaagt aaagctaaac aatagggcta taccattcta
    31321 aacattatag tagaatgcaa ctttctctcc ccaagaagta cgaatccatg cacgagaagt
    31381 ccctccagca ccagcatatc ccttgtcaga tgaaccagtt tttctgctaa caactgttga
    31441 actatggtat tttgaagggt gatagtagtt tgagtaagca ccaccgttac ctgaaccata
    31501 agtccaaaca ccaccttctg ggtattgaac ggctgcagag gcaactgcta cacttccacc
    31561 taatgttgct gcaatgctcg ctacaagagc taatttttta actgtttgtt tcatattgat
    31621 actcctctat ttttgattac aagattgttg agttacttgc tcctctttcc attatcaacg
    31681 ttgatactat tatattacca aatgatattc taaaattatt tgtttttctc taaattgtca
    31741 aaatagcacc ctgaaatgaa cttttatagt cattatactc catctttatc acactatcaa
    31801 ggacatcaat gtccttaaaa tctaactatt tcatattatt tttagcttat atctaaaaaa
    31861 acagttctaa agacgaactt tagaactgtt ttgatacgag gacaaggaca tttttgtcac
    31921 tgattcacta tgtttataaa tattttttga catcctcttg ccattcctct gtcaatttct
    31981 ttactagaaa tccatctcca attagcttcg caaatgtttt agaagactga taaaatgatt
    32041 cagctaaact aaaatctctt tctactctta atgcttgctt ccacaaaaac ataaatacaa
    32101 gaggtttctt ttgataatct tgagttttat ccataatttc ttgtaaacac gatagataat
    32161 cattaaaaca atcagttact cctacctttt caagacaaca cattcctgaa ataagagtat
    32221 ctctaattat aaagtaattc tctatttgag ttaccttctt ctgttccaaa agaaagagca
    32281 ttagcttttc gatttgattt ataaatttgg caagatcttt tctaatgagc atttgataaa
    32341 aaaacaaacg aatcaacaac atatcattta ttgaataagc ttctttttct ataatctgag
    32401 gcatatgttc ctcaagtatt aactctgcat attcaggcct tctagttcta gaagtatcca
    32461 aacacgcctg caatacttca catgctaatt gttcttcttt aggaagatta tcaaagtatg
    32521 ttttataaat ctcttccaaa cacgcttcct tcttatcgta ctcctcttct ttaccataga
    32581 ttggttcacg taaaatctgg tatttcaatt ctaaataagc agaaggaaga gctgaaaaat
    32641 ccggcataag gctataaact ggaactccta gccggcgagc aatataggct aacttgggca
    32701 aactcggttg cgaagctcca ctttcaattc gcgacagttg acgaactgtc agttcttgct
    32761 catctccaca aaaatctgga cgactaattc ctttttctat ccgaatctct ttaatttttt
    32821 gaccaattaa catcagacgc ctcctcttct acctgcttcg aaaaatactg tgaaacttaa
    32881 aaaattgtaa cggctacatc tttcctactc ataagatttc atagcttctt ccacttctgc
    32941 caaagtaacc ccaaacaact ctaggcgttt gaggagttgc ttgccgttag aatagccgat
    33001 tcggagagtc tctccgagat attctctacg cttacggctg tctgcccctg ctagaaaacc
    33061 aaggcgaatc aaatcgctac gactaatgtc aaactgactc tcatgttcaa attgttctgt
    33121 cacctgagct agagccgttt tcaggtcttc atagctggca tgctcaattc ccagagaacg
    33181 ccccttggtc ttggacttgg gaacagcttc atctcgcttg agaaaggcat gctgaactgt
    33241 tggaatggcc gtcataatca tgcgccgaat ccgctcccca ttaaaatctg ggtctgtaaa
    33301 gacaatgact ccatgacgtt ggtgtagacg ctgaatccgc tctatgtcct ggtcattgat
    33361 ggcagaacct cgagtctcat aggtctccac atcgaaataa cgcttgagat tgaccgtatc
    33421 atcacgacct tcaaccacga taacttggga aattctctct ttcattactt gctgtccaat
    33481 ccaaaaatgc gttctgcatt tgcagtcgtt gctaccgcca gctcttctgt cgtcatacca
    33541 cgcaagtcag cgataaagtc gaccacatag cgagtatagg ctgttttatt ttcacgacca
    33601 cgcttgggta caggtgctaa gtaaggcgca tctgtttcta ccaacatctt gtccaaaggt
    33661 aactctttag ctgcttcttg gaggtcagtt gccttcttga aggtcaccac tcctgagaag
    33721 gaaatggtca taccaagatc cacaaacttc tctgcccact caagcgtccc tgaaaatgaa
    33781 tgcatgatac caccacgagg accaacgccc tcactcttga taatctcata ggtatcttcc
    33841 agcgcatcac gggtatggac aacaaaaggc aaatccaagt ccttagatag ccgaatctga
    33901 cggcgaaaaa cctgctcctg cacctctttg ggcgctgtca tccaatggta atctaagcca
    33961 atttcaccta aagccacaac cttgggatgt tttaacttat ccaacaagta agcctcaact
    34021 tcctctgtat aagtaccagc ttctgtagga tgccaaccaa tagtcgcata gagctgctca
    34081 tactcatcta ccaactccaa ggcacgctca atcatcggtt tatcaaaacc aacaatattc
    34141 atctgtatca cacccatctc agcagccaag gcaatttctt ctgcctcacg acctgcaaat
    34201 tcttctacat tcaagtgtgt atgtgtatca aaaatcatct cttctaacct cgttttctat
    34261 cttctattat accaaaaaag aggaggggca cctaattttt cggtttcccc tcctctcttc
    34321 aatagagagc tattctgcta tcttttctat ccgatattgc ccatctccta ttccacagtt
    34381 agagacagaa gagattggct acattgatag aatattccta ttcagctaaa gtatgtgatt
    34441 atcttgggtt ctcacttttc tcacccatca ctaggattga tgacttctca aaatccccct
    34501 tataatctaa ctttaagtag agaatagaat tttctagctg ttctattttc tacgtctagt
    34561 ctttcttcct agcaaagcaa aaccacttgt tgccaccact agaccaagac tagcaagtgc
    34621 tgcacttgat gctgaacctg tgttaggtaa ttgtttgcca gcaggtgact ggtaggtaac
    34681 atcttgcatt gttcctgcag ttgcttgcgg tgcacttgtt gtcttaggag cagcattagg
    34741 agccactagt ctcttaggaa ctgtaaccat ggcaatggct tgcactccaa tcgtttctgc
    34801 ttccttcaca tcttccatag ttttcgcatt ttcaatctct ttgagagctg cttgtttttc
    34861 tgcttccact cttgctaaaa gttctgcttt ttctttatca gaaagcggtg cgcctttgat
    34921 ttcatcctgc ttgtccttgg ctgctttttc aatggcattt ttagctgatt ctttttcagt
    34981 agctaattgc ttagaagctt gtgattgagc tgagttttgt gaacctgtgt gagctgatcc
    35041 acccgcctgg ctaccaccgc cttcattcgc attagcatct gagcttccaa tattgcctcc
    35101 cttatctcca cctggtgtag tttctagctt atactctggt gtaacttctt gagttacaga
    35161 ttcacctttc gcagattgtt gaactgtatc ttttcctaga atcgtcacta ctgaaccatc
    35221 tgggaatgtg attgttgctg taccatctcc agctacattg attgtcgctc cgtctaatgc
    35281 tgaaccattt gcttgtaaaa tagcaacctt aactttttct tcatctgtta aatgagttat
    35341 atcttttaca tctactcttt gagcaggtgc tttaacagtt gatttttcag cagtcggttt
    35401 agtgctatct tgtgcttttg gatcttgtgc taccaattga tttcctggaa ttgtaatagc
    35461 tgaaccatct ttaaagacga ttgttgctgt accatctcca cctacttcaa ctttatagta
    35521 aaataaaata ataacaggac aaatcgatca ggacagtcaa atcgatttct aacaatgttt
    35581 tagaaacaga ggtgtactat tctagtttca atctactata acatcgcttc cgaatccatt
    35641 tgcatctact gaactttttt acaaaaataa aaatcagtag actcgagttc ctactgattt
    35701 ttgatagaat tcgtttggat tatgcagcca aaactttgcg tcctttacga cgacgagctg
    35761 ccaatacgcg acgaccattt ttagttgaca tacggttacg gaatccgtgt ttgcgcgcac
    35821 gacgaagttt acttggttga taagtacgtt tcacgatgaa tacctcctca tagattttgt
    35881 attcgtttag ccggctataa agtgatcagt tactaaacat actttactat tctatctgat
    35941 tctttcactt ttgtcaatag ctctaggcaa atgtttccag ctttttcgaa tgcaagccct
    36001 atctacgata ctgtttcaag aaacgagtca tcttttcttg gatttgggct aactcatcaa
    36061 cacgaggaag gtaaacgata cggaagtggt ctggttcctg ccagttaaag cctcgaccat
    36121 gaaccaagag aaccttttcc tgcttcaaga aatcaaggac aaactgctca tcatcatcga
    36181 tacggtacat attgcggtcg atttttggga agatatagag ccccgccttg ggtttaacgg
    36241 cagacaaacc tggaatatct tgaatggcat tatagatgaa atttctttgc tcgtagattc
    36301 gtccaccagg aagaagcaat tcatcgactg attggtgacc ccccaaggaa gtttgtacga
    36361 cttgttgggc caaaacgtta gagcaaaggc gcatattgga cagcatattg agcccttcga
    36421 tatagccctt aacatgagtc ttagggccag acaagaccat ccaacccaca cggaaacctg
    36481 ctatgcggtg ggattttgac agaccattca tgctgacaca gaagacatct ggtgccaagc
    36541 tcgccacagg cgtatgcaca tgtccgtcca ttaccatgcg gtcatagatt tcatccgcaa
    36601 agataatcaa atcgttttga cgggcaatct caataatctc cagcaagagt tccttaggat
    36661 aaagggctcc agttgggtta tttggattga taaggacgat tgccttggta ttggaagtga
    36721 tttttgactt gatatcgtca atatctgggt accattcaac agcttcatca cagatatagt
    36781 gaacggcatt tcctccagct aggctgacag ccgccgtcca tagaggatag tctggcattg
    36841 gcactaagac ctcatcccca ttgtccaaaa gcccctgcat ggacatgaca atcaactcac
    36901 tgacaccatt tccaaggtaa atatcatcaa tatctacgtt tgggaatttc ttcagctggc
    36961 aatactgcat gatggcctta cgggctgaga aaatcccttt ggagtcagaa tagccttcac
    37021 tatcacgcgc attcataatc aagtcatgaa tgacctcgtc tggcgctgta aagccaaatt
    37081 ctgctggatt tcctgtattc agacgtaaaa tcttttctcc attcgctcgc atccgcatgg
    37141 cttcttccaa tacaggacca cggatatcat aagcaacatg ctctaactta ctagacttgt
    37201 tatattcttt catcttgttt cctcaattca tcaggatagt aacattatac cactagaaag
    37261 agaatgcgac aagtttactg aaatgtgtta ctagtttcgt atagaagaaa aaccttgcta
    37321 aaggcgaggt taagaacgta gagatagcag gtattttgca aagacacatc acataccaaa
    37381 agataaacct agaaaaagca agcctagaaa ggagtcataa agaagattaa acatgaggaa
    37441 aagcccccat atcatcaagt aatcccaacg cccacttcgt tttgcaacta gaaataagat
    37501 tagatggtag agtacatgaa agactaaaaa tccaataaaa cttggataaa gaagcggtac
    37561 cagactctct aattgacaga tcatgatcac ttttaccaag actgaaacta ggataattcc
    37621 ataataaagg aaatttgatt tttgaaaaga gtttttcatc attctccttt cctcctatcc
    37681 tttcttttat tttatcatat atttatatag agtttaagcc ctaatattct tttgaaaaat
    37741 actttttttg ctttacttct atagtgaaaa ggtttacaat tatagtaaga aaatttcagg
    37801 aggtttcatt atggcacaac gttaccaaaa tatcatggtc gcaatcgatg gttctaagga
    37861 agcggacttg gcttttgtca agggagttca ttctgctcta cgaaacgacg ctaaactcac
    37921 catcgcacat gtcattgaca cacgcgctct ccaaagcgta tccacctttg atgctgaagt
    37981 ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa gagtacgaaa aacgtgctaa
    38041 agatgctggg gtagcagatg ttcatatcgt cattgaaatg ggaaatccaa agaccctgct
    38101 agcacgtact attccagatg ccgaggaagt ggacctcatc ctcgtgggcg caactggtct
    38161 caacgccttt gaacgcctct tggtcggctc ttcatctgaa tacatactcc gccatgctaa
    38221 ggtcgatttg ctggttgtga gagaacaaga aaaaacctta taatcacaaa gaaaaggagc
    38281 ccctagctcc tttttgttta cgatttattt ctctctttat ggcgttcgta agccttgagc
    38341 tggcgatgca gttccttttt aatagcaggt tctggagcat atttttcttc ccaattatct
    38401 ggttttaaga ttttatgggt cactggatca aaatgagcct tgccatctgg aaaaattttc
    38461 cccatattgg cctgatggac aatatcaaaa atacgttctg ggtccacccc catcaagaca
    38521 aaactgccgt aggtgaagta aagcgtgtca atcaaggcat ccacttgccc tatcaaatct
    38581 tgctgagcag gtgtcttctt ggctacttta cctgctgcct tatcaagggc ctgatgaagt
    38641 tgcgatacag cttgaccaaa atcttcttca gaaggactgg ctgctcgaac aaactccacc
    38701 aattcttcta ttttaaaacc agccctatgg gttgcaccct ctaaatccca agctcgaggt
    38761 tcttcttggg ttcgttcatc catcatgtgg tggaaggtct tgaccttatt gaaatgatag
    38821 tcacggctga caaagacttt ttctgaagac aaaacaccaa aatgttccaa ggccttgtgg
    38881 atcccatctt gttgattgct agtggtaatg tgcttggcag cttccttgac actgctacta
    38941 ccatttccca tagcgaccga cataccgacg ccagccagca tttcaaggtc attatctgag
    39001 tcaccaaaag ccatgacttg gttgaggtca aagccatatt ctttcccaac tcggcgaatg
    39061 ccttctaatt tagaatttcc ctgattgatg acatccgatg caaaaggatt gctacgtgtc
    39121 aatttcaagt cttcaaaatc agctgccgcc ttctcagatt cttctggtgt catcagcatc
    39181 aaaacttggt agataggctg attcatcagg tgaagcaggt cctcttcctt ttggggaaca
    39241 accttgctga ccatgcgatt aaaagactga ctcaccgtcc gagttaaaac agagggaacg
    39301 aagcgactaa ttcgttggga aaaagaaccc agaccaaagg acatgatttt agaacccaac
    39361 atggcatcct tggtccctag agcaatctcc gtgccctctt ttttagcata gctaattaga
    39421 tggcgcaaat gtaacttgga aatagggctc gtgaacaaga ctctgtcttt actaaagata
    39481 tactggccat tataggttac cgcaaaatcc agatccaaat cgtccatcaa ttccttaaca
    39541 aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc cttgttcttt gacaatctta
    39601 atcgcgtcct tagtggattt caaaacactc ttgcgattgt tgaccaaggt tccatcgata
    39661 tcaaaaaaaa cagctttgac ttccatccta ttccaatctc cccttttgtg atacaatgat
    39721 tataccacat ttcagaaaga gtgagtaaat catgcctaag aaaatccttg ttttacatac
    39781 gggtggaact atttccatgc aggccgatgc ttctggcgct gttgtgacga gttcagataa
    39841 tcccatgaac catgtgtcca acccacttga aggaatccaa gtccacacct tggacttttt
    39901 taaccttcca agtccccata tcaaacccaa acatatgctg gtcctctacc agaaaattaa
    39961 agaggaagca gataactacg atggagtggt gatcacacac ggaaccgata ctttagagga
    40021 aacagcctat ttccttgata ccatggaagt tccccatatg cctatcgttc taacaggagc
    40081 catgcgtagc tccaatgagc tcggtagtga tggtgtttat aattacctaa gtgctttacg
    40141 agtggccagc gatgacaggg ctgctgacaa aggagttttg gtcgttatga acgatgaaat
    40201 ccacgctgcc aagtatgtca ccaaaacaca tacgactaat gtcagcacct tccagactcc
    40261 aacacatggc cccctcggtc tcaccatgaa acaggaaatc ctctacttca aaacagctga
    40321 acctcgtgtt cgctttgacc ttgatcacat acaaggttta gtccctatca tctcggctta
    40381 tgctggtatg acagatgagc tgattgatat gctggattta gaacacttgg acggtttgat
    40441 tatccaagcc ttcggagctg gtaatattcc caaagaaacg gctcaaaaat tagaaagcct
    40501 tctgcaaaaa ggaattccag tcgctctggt atcacgatgc tttaacggta ttgccgagcc
    40561 tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa gcaggcgttt tctttgttaa
    40621 agaactcaac gcccaaaaag ctcgcttgaa actcctcatc gccctcaatg ccggactaac
    40681 aggacaggct ttgaaagact atatggaagg ctaatactct tcgaaaatct ctgcaaacca
    40741 cgtcagcgtc gccttaccgt atgtatggtt actgacttcg tcagttctat ctacaacctc
    40801 aaaaacatgt tttgagctga cttcgtcagt tctatctaca acctcaaaac agtgtattgc
    40861 gcagccttta accagccgcc tagtccgctc tatggtattc attaagtcaa catctcttgt
    40921 ttaagagcac aaaatcagga aatcttctcg attccctgat tttttctatt tacgttttcg
    40981 tgttgagcta cgttctgtca aaccatgagg taagagaact tcacgttctt ccaactcttc
    41041 cttatgcata atcttggtca acatacgcat actaatggca ccaaggtcat aaagaggttg
    41101 ggcaatcgtt gtcaagtttg gacgggtaaa gcgtgagatt tgtgaatcat cactagtaat
    41161 aatttcaaaa tcttctggca cagaaacacc cttatcagcc aaaccgttca agactcctgc
    41221 tgccaactca tcacctgtca caactgctgc agttgcattt gatgaaatca aacgctctgc
    41281 taaggcgtaa ccatcatcat agctatattt agattcaaat accaaaccct cactataagt
    41341 gattcctgct tttttcaagg tttccttgta gccaactaaa cgaaccttac cattgatgtc
    41401 atccactagc ggaccgctaa cgaaagcaat acgctcattt tctttagcaa ggtaactcac
    41461 tgcatcaatt gttgcttgct tatagtcaat attgacactt ggcaactggt gctcaacatc
    41521 gacagttcct gcgagaacaa tcggagtacg tgaacgcgaa aattctgagc gaattttatc
    41581 tgtcaagtga taacccatat agataatgcc atctacctgc tttgaaaaga gggtattgac
    41641 aacagaaact tctttctcgt tatcttcatc gctattagct aggacaatat tgtacttgta
    41701 catttctgca atatcatcaa tccccttagc caaactcgaa aaataaccat tggtaatatt
    41761 tggaatcacg acaccgacag tggttgtctt tttacttgca agaccacgcg caactgcatt
    41821 tggacgataa tccaaacgat caattacctc tagcactttt ttacgggtat tctcttttac
    41881 atttttattg ccattgacca cacggctgac cgtcgccatg gaaacacctg cttcacgagc
    41941 gacatcataa atggttactg tatcatctgc attcattcct tttcctgtcc tttctatctc
    42001 acacattctt ttacaagtag aggtactgat tgaagctcta tatctactta caaaagtgaa
    42061 gatgtgaaaa tttcgttttc atatttctac ttattccatt ctatcactaa ttgtaaacac
    42121 tttcaagtgt tttttgaaga ttgattgaaa aaatttcata gaaaacctag gtttagctcc
    42181 ttgctaccac cttagactaa acaaaaagga ggaaactaag ccctcctaaa gttatagtaa
    42241 aatgaaataa gaacaggata aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    42301 agaagtagag gtgtactatt ctagtttcca tctactatag gtattgttcc attcactacc
    42361 gtcaatttta gcacatagtc ttcatgaaaa tattatatca tcataaccaa ccagattctt
    42421 ttgcgatatt agctgcctct gttcgattac cagcatccag ttttgaaaga atattggtga
    42481 catagtttcg aatagttccg tttgagaggt aaagctgatc tgcgatttct tggttggata
    42541 agccccgggc gattcccttt aagacagcaa tctcttgttc tgtcaacgga ttgggacggg
    42601 tcatcaccac ttccatcaat tcaggcgaat actccttgcg tccttcgagg acggtgtgca
    42661 aggtttgcat gaggtctgca atgcttcgtt cctttaatac ataagcatcc actccagcct
    42721 tgaccgcacg ttcaaaatac ccagcacgct tgaaggtcgt caccacagcc acctttgttt
    42781 caagcctttc tgatcgtatc cactccaaga cttcaagacc tgtcttaaca ggcatttcta
    42841 cgtcaaggat ggcgatatct acagactcct tttctaatag ttggattgct tcttgcccat
    42901 tcttggcttg aaggacagac tccacatctg gttgaagcgt gagcaattga cacatggcat
    42961 ctcgcaacat actttgatct tctgcgacta atactttcat cttagtttct ctccttataa
    43021 ggtagtcgaa cttgcacttc cgttggatgt ttctgactga ttacacttac ttctcctgaa
    43081 aatggaaaaa cacgatctcg gactgtatgg agctcatctc cttttagaaa agcaaagccg
    43141 cagccatcat cacttactgt taaaatgagt tccttctctg tccgttctaa ttttaagtaa
    43201 gctttagacg ctttggcatg tttgatgata ttggtcacca actcaagcaa aatcatagaa
    43261 gccattgaat ccaattcttg agtaaggcta gcagtatcta gttggttatc tgtttccacc
    43321 tcaattccag caatttctaa catctttttc acagtctcta gttcggatgt caaagttcta
    43381 gacttaagat tttccacaat ggttcgaact tcacacattg attctttgct aatttgctgt
    43441 atttctctta attccttttc cacttgtgga taagcctgca tttgaaatag ctgcaaggct
    43501 agatctgtct tgacactaag catagcaaag gtatgtccca gactatcatg caaatcctga
    43561 ccgatacgat tgcgctcatt ttctgctagc aatagattta tctgggtatt ttgcttgacc
    43621 tgagcttctt tcaaatcctc gacaaggcga attcgaaccg agcccaaagt catcaaatcg
    43681 acaaaagtaa gaattacaag catatagact agaaactcaa cttcgattct ctgaaaaatc
    43741 aaaagtcgcc ccacaacaag gacttgagca aggagaaatg tccatacatg taaagacttt
    43801 aaactacgta cgccaaaatg ataaattaag agattggaaa ggaaaaagaa aaaccagata
    43861 taattcccag caacaaaggc ggtattccca gctacataga ccagcatgag cccccagaaa
    43921 agccaagata ggcgctggtt cttagttatt aaaacaccca aatacgtcac tacaaataga
    43981 atatcaacca ataaatgcca agcaggaagc tccccaatca ctacaggtag gatgggaaaa
    44041 agcataaaaa tcaaactggt ccaaaacata tagtgtatgc ttttcagtct ttcaagcatt
    44101 aagcattctc cttatgacct tgaaggtaaa tagtcaaacc aaataaaact gctgaaaaaa
    44161 caagtaaata aactgtggct gatagattga tgtcaccctc gtttaagaag gtcttgagca
    44221 actccatcaa ttgataggtc gggagacact taccaactgc ttgcatccag tctggaaata
    44281 aagaaatggg catccagagt ccgcctaaaa cagccaatcc tagataaaga agattgccca
    44341 caacagacat cagctgacta gttggtaaga gagtcaaggt caagccaagt gctacaaaag
    44401 caatactccc cacaatcagc aaaatcgcag ctccaaccca ttttactaga ggcatgtcta
    44461 cacctcttac aaaatgtcca actgtaaaaa caaccagaat tgagaccaaa taatcaacca
    44521 gcatacttgt tatctttgat agataatatt ctaccatatt tacagggcta tgacgcaatg
    44581 ttttctgcca gttgttcatc ttatcggtat gtaaaacagc tggaaatgag aggatagttg
    44641 tcgacatcat ggaaaaggca gtcatggaga tgaggtaatc acgcataaaa ttcgcgagtt
    44701 cacctggtgt gtcctgatag ataccagaaa aaaataaata gaaagccgtc ggcatcccta
    44761 ccgacaatag ataatagatt aattgtcgtt tggtcaataa aaattctatc ttactaagtg
    44821 ctatccatcg tttcatctta gttatctccc ttctgcgtct cttcaaagat tgtattcaac
    44881 aaactacgat tattaacttc gatttcttgc atcctacatc ctgcttgggc taatagttcc
    44941 cagaaagcat ctgcttctcg agtgactact tgtaaagaat cttgctttag ggtccagttt
    45001 tcaaccaaat ttgactgctc tacgacttcc ttgtaagcta taggaaggat aaagtgcttt
    45061 tctatttcct cgctacgcat agctagaggc gtcgtatctc gaatcaactc tcccttattt
    45121 aagagcaaaa tgcggtctgc agtgtgttcc acttcctcaa tataatggga cgaatagaga
    45181 atggtaactc cctgcgcttt tagatcctga acaatttccc aaaaacgttg gcgggttgag
    45241 gtatccatgg ccgcagttgg ctcatctaaa aagacaagtt ttggtcggcc aatcaaggtc
    45301 aagacaaaag agaaaagacg cttttgccca cctgacaatt tttctgccaa ttgctctttc
    45361 tgttgcttgt caaactgcaa cagttgatcg atttcctggt tgctcaaggg atttggataa
    45421 atgctttgaa agaaagcaac caactctttg acctttaatt tctgaacgat gacattttct
    45481 tgaggcagat aacctctaat atagtctaac tgagaactcg tcactgacaa gccttggatg
    45541 gatacttgac cgcttgtgac cagtttatct ccaagcagac agtccaagag tgtggtcttc
    45601 ccagcaccat ttggcccaat caaggcgacg cattcacctt cagctacctc aaaggaaata
    45661 tccttcaaaa tagcctttcc cttgatgttt ttatgtaatc cttgaacctt aatcatgtcc
    45721 atgatattct cctttcaacc actccattcc cataggaaag gcgataaaaa tcataaatcc
    45781 tagtccccag gcaccacgga tgaattggcg aagcaaggct tgatcaaacc aacctgtaaa
    45841 catttctacc aaccatacca ctagtgatag tccaataaaa agatagagaa acgctttttt
    45901 catttttcaa actccttttt cacatctgag actaatttca aaccttctcg gataagccag
    45961 gacatcattc caaatcctgc aaatagctcc caaggaaaat gatagaaatc ttcatccaat
    46021 cctgagaaca tgagataagt catgactcct gctgctacta aactcattgc gacaatcatt
    46081 ttatttttca tctcttcttc ctccgtttca tacttcaatt atagactttt gaagttggcg
    46141 gagctagatg cttctgtcac tagaaaatat gacaaatgtc ataaaaattc tgtacaaaac
    46201 aagcaagata cactatataa taaaacacaa gtagaaaaaa tctaaggcag ctttcaaaag
    46261 agatatcaaa cccaattcac accataatgt aaactaatac ttatttaaaa tcaaaaagag
    46321 cggaaatttt tatcgcacaa acacatatat tataagcaga gcgaaaaact cttcaattac
    46381 tttcttaaaa gtttgtaaga attatacaat ctgttaaatt ttaatttatg tacctaaact
    46441 acagtattca ttgaacaaat taggaaacaa aaaagtatac gctgctaaaa tgaattactg
    46501 aaattcaaaa aagagagaag caaactgatt ctctcttaat gtatataata tctagttaaa
    46561 acaaaaagat acgcttacgt atctctgaaa
//
LOCUS       DAVLZG010000007        42760 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLZG010000007 DAVLZG010000000
VERSION     DAVLZG010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.007"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(385..777)
                     /gene="rpsI"
                     /locus_tag="VYO72_000400"
     CDS             complement(385..777)
                     /gene="rpsI"
                     /locus_tag="VYO72_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1706840.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(797..1243)
                     /gene="rplM"
                     /locus_tag="VYO72_000401"
     CDS             complement(797..1243)
                     /gene="rplM"
                     /locus_tag="VYO72_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1706841.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1599..1916
                     /locus_tag="VYO72_000402"
     CDS             1599..1916
                     /locus_tag="VYO72_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1706842.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(2066..2878)
                     /gene="folK"
                     /locus_tag="VYO72_000403"
     CDS             complement(2066..2878)
                     /gene="folK"
                     /locus_tag="VYO72_000403"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1706843.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2921..3475)
                     /gene="folE"
                     /locus_tag="VYO72_000404"
     CDS             complement(2921..3475)
                     /gene="folE"
                     /locus_tag="VYO72_000404"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1706844.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3456..4778)
                     /locus_tag="VYO72_000405"
     CDS             complement(3456..4778)
                     /locus_tag="VYO72_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1706845.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4780..5754)
                     /gene="folP"
                     /locus_tag="VYO72_000406"
     CDS             complement(4780..5754)
                     /gene="folP"
                     /locus_tag="VYO72_000406"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1706846.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5849..6556)
                     /locus_tag="VYO72_000407"
     CDS             complement(5849..6556)
                     /locus_tag="VYO72_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1706847.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6609..8027)
                     /locus_tag="VYO72_000408"
     CDS             complement(6609..8027)
                     /locus_tag="VYO72_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1706848.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8217..9029
                     /locus_tag="VYO72_000409"
     CDS             8217..9029
                     /locus_tag="VYO72_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1706849.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9368..10387
                     /gene="adhP"
                     /locus_tag="VYO72_000410"
     CDS             9368..10387
                     /gene="adhP"
                     /locus_tag="VYO72_000410"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1706850.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKGKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10621..11610
                     /gene="manX"
                     /locus_tag="VYO72_000411"
     CDS             10621..11610
                     /gene="manX"
                     /locus_tag="VYO72_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1706851.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11638..12441
                     /locus_tag="VYO72_000412"
     CDS             11638..12441
                     /locus_tag="VYO72_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1706852.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12465..13376
                     /locus_tag="VYO72_000413"
     CDS             12465..13376
                     /locus_tag="VYO72_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1706853.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13432..14766)
                     /gene="pepC"
                     /locus_tag="VYO72_000414"
     CDS             complement(13432..14766)
                     /gene="pepC"
                     /locus_tag="VYO72_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1706854.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(14983..15705)
                     /locus_tag="VYO72_000415"
     CDS             complement(14983..15705)
                     /locus_tag="VYO72_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1706855.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DINTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     KPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(16018..16248)
                     /locus_tag="VYO72_000416"
     CDS             complement(16018..16248)
                     /locus_tag="VYO72_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1706856.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(16258..17499)
                     /locus_tag="VYO72_000417"
     CDS             complement(16258..17499)
                     /locus_tag="VYO72_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1706857.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(17521..17673)
                     /locus_tag="VYO72_000418"
     CDS             complement(17521..17673)
                     /locus_tag="VYO72_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706858.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(17694..17972)
                     /locus_tag="VYO72_000419"
     CDS             complement(17694..17972)
                     /locus_tag="VYO72_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1706859.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(17965..18228)
                     /locus_tag="VYO72_000420"
     CDS             complement(17965..18228)
                     /locus_tag="VYO72_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1706860.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(18330..22721)
                     /locus_tag="VYO72_000421"
     CDS             complement(18330..22721)
                     /locus_tag="VYO72_000421"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1706861.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VDKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(22825..24906)
                     /gene="fusA"
                     /locus_tag="VYO72_000422"
     CDS             complement(22825..24906)
                     /gene="fusA"
                     /locus_tag="VYO72_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1706862.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(25331..25801)
                     /gene="rpsG"
                     /locus_tag="VYO72_000423"
     CDS             complement(25331..25801)
                     /gene="rpsG"
                     /locus_tag="VYO72_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1706863.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(25821..26234)
                     /gene="rpsL"
                     /locus_tag="VYO72_000424"
     CDS             complement(25821..26234)
                     /gene="rpsL"
                     /locus_tag="VYO72_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1706864.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            26651..30448
                     /gene="spuA"
                     /locus_tag="VYO72_000425"
     CDS             26651..30448
                     /gene="spuA"
                     /locus_tag="VYO72_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1706865.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(30548..31597)
                     /locus_tag="VYO72_000426"
     CDS             complement(30548..31597)
                     /locus_tag="VYO72_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1706866.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SDGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHIPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            31654..31791
                     /locus_tag="VYO72_000427"
     CDS             31654..31791
                     /locus_tag="VYO72_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706867.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTNEVSNHTYGKATLTWFEEI
                     F"
     gene            complement(31868..33676)
                     /gene="glmS"
                     /locus_tag="VYO72_000428"
     CDS             complement(31868..33676)
                     /gene="glmS"
                     /locus_tag="VYO72_000428"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1706868.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYFEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(33869..35248)
                     /gene="bglA"
                     /locus_tag="VYO72_000429"
     CDS             complement(33869..35248)
                     /gene="bglA"
                     /locus_tag="VYO72_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1706869.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(35348..37201)
                     /locus_tag="VYO72_000430"
     CDS             complement(35348..37201)
                     /locus_tag="VYO72_000430"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1706870.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(37214..38473)
                     /gene="rseP"
                     /locus_tag="VYO72_000431"
     CDS             complement(37214..38473)
                     /gene="rseP"
                     /locus_tag="VYO72_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1706871.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGGKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(38495..39298)
                     /locus_tag="VYO72_000432"
     CDS             complement(38495..39298)
                     /locus_tag="VYO72_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1706872.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(39307..40065)
                     /locus_tag="VYO72_000433"
     CDS             complement(39307..40065)
                     /locus_tag="VYO72_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1706873.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(40296..40760)
                     /locus_tag="VYO72_000434"
     CDS             complement(40296..40760)
                     /locus_tag="VYO72_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1706874.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(40849..41820)
                     /gene="ruvB"
                     /locus_tag="VYO72_000435"
     CDS             complement(40849..41820)
                     /gene="ruvB"
                     /locus_tag="VYO72_000435"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1706875.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            41981..42073
                     /locus_tag="VYO72_000436"
     CDS             41981..42073
                     /locus_tag="VYO72_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1706876.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT        12447 a         9883 c         8264 g        12166 t
ORIGIN      
        1 cttccccatt ctatggaatc ttgcattatc cataatatag tagattgaaa ctagaatagt
       61 acacctctac ttctaaaaca ttgttagaat tcgatttgac tatcctcgat ttgtcctatt
      121 cttatttcat attactataa aaataaggta aacttttcaa aaaagcacga aaaaagcacc
      181 cataaggtaa acttttgagt gctttgaaac attgatataa tcgtattgat taacgttttg
      241 aggcaactga ccttgtcagg ttgcagccac atttgtaagc gactaaagtc gcaacaactg
      301 tgtcaattgc accaatttag taagaaagta taaaaaaaga acaccccgaa aggtgctctg
      361 tataagtata gtaattcttt cgaattaacg tttactaaat tgtgatgctt tacgagcttt
      421 cttaagacct ggtttcttac gttcaacttt acgtgagtca cgtgtaagaa gtcctgcgcg
      481 tttcaatgaa tcgcggaagt ctgggtctac ttgaagaagg gcacgagcga taccgtgacg
      541 gatagctcct gattgaccag cgtatccacc acctacaacg ttaacgaaaa cgtcgtatga
      601 acctacagtt gaagtaactg cgaatggttg gttgatgaca agacgaaggt cagcgtgtgg
      661 gatgtactct tcaacatctt ttttgttaac agtgatttta ccagttcctg gaacaaggcg
      721 aacgcgtgca acagcgtttt tacgacgtcc agtacctgca tattgtgctt gtgacatact
      781 ttatttgttc ctttccttag ataagtcctg aaatgtcaag aacttctggt tgttgtgcag
      841 catgagtgtg ctcagctcca acaaatactt tcaacttcat accttgagcg cgtccaagtg
      901 tattgtgtgg aagcatacct ttaactgatt tctcaatcaa acgtactgca tttttagaac
      961 gaagttcacc tgcagagatt tgtttcaatc cacctgggtg gtttgagtga gtgtagtaga
     1021 ttttatcagt tgctttttta ccagtcaatt taactttttc agcattgata acaatcacga
     1081 agtcacctgt atcagtgtgt ggtgtaaatg ttggtttgtt ttttccgcga agtacgctag
     1141 caactactgc agaaagacgt ccaagtggta catcagttgc gtcaactacg taccatttac
     1201 gttcaacttg gcctggttta gccataaatg ttgttttgtt catgatttct cctatatata
     1261 gttcgatttt tgtttacggt gatgggtgtt ccttcccatc gaaaagtatt tggaaggttc
     1321 cggggccttt caaatggggt aaacaatacc gcctactatc ataccaaatt tcacccctaa
     1381 aagtcaatag atatgaaaaa tatttttcgg taacttctca aagtaactga aagttatata
     1441 atcaagttaa tttgggaatt tacctattaa cttcggtaga tttttaggaa ttttttccct
     1501 atttctccct gtaactaaaa tccttttcaa aaaatcacct tttcttgatt tttaatccta
     1561 tttgctgtat gataagggaa aagaaagggg acagagatat ggcttttacc aatacccaca
     1621 tgcgatctgc tagttttggc attgttacca gcttgcctga tgacatcatt gactcttttt
     1681 ggtatatcat cgaccatttc ttaaaaaatg tctttgaatt ggaagaagaa ctcgagtttc
     1741 aattgcttaa taaccaagga aagattacct tccacttttc aagtcaacac ctccctacag
     1801 ccattgattt tgactttaac catcctttcg accctcgtta tcccccaaga gtactggttt
     1861 tagacatgga cggtagagaa actatcctcc tcccagaaga aaatgaccta ttttaatact
     1921 caatgaaaat caaagagcaa actaggaagc tagccgcaag ctgtacttga gtacggtaag
     1981 gcgacgctga cgtggtttga agagattttc gaagagtata aaaactctag ccttcagttg
     2041 caagtaactg aaaactagag tttttctatt ttttcaaagc atcatacaag ttgcggatcg
     2101 gttgttttaa tatcggatgg ataaaatgag gcgcaatttc ctgtaaggac tcaaggacaa
     2161 aaaggcgttc cgctatgtaa ggatgaggca atatgaggtc gtctgtataa aggatctggt
     2221 cctccacaaa gagcaagtcc aaatcaatca aacgaggtcc ccaatgcact tctctcaccc
     2281 gtcccagctc tgactcaatg gctaacaagg tttctaacaa gtcttgtgct ggtagccagg
     2341 tttccacctc aaccacttga ttggcaaagc tatcctgctc cactccaccc caaggctccg
     2401 tcgctaagac actggactct ttgagaatat ggatgccacg agctcgcagt ttgtcaatgg
     2461 cttgcttcaa gtttacttgt ttatctccca tattgcttcc tagggcgata aaggctcgtt
     2521 gcttgcggcg atgaatggtt accgagcaag tatctagtga caaatgcacc ggtgcccaag
     2581 gttttttcag ttccaacttc atttcttgga caagaggata agactcaaag gtacgttcca
     2641 ccagtttata ggctaccgtt tcaatcaaat cttcactcgt ttcctgaaac caagtcgtcc
     2701 actgctgaca caattctccg taatggacag aggctgttaa atccaagtct gtagctgcct
     2761 tggtcatatc ataggatagg atggctgaaa cgacaaattt ctgccccaat tctttctcac
     2821 taggaaaaag accatgatag gcaaacattt ccaaatcctt aatctgcagt tgatccataa
     2881 tgattccttt ctagaaaaat ccgcttgaag cggattcttt ttatagcccc attaaacgat
     2941 aagcttggtc gcggaggtcc ttatctgttt caaatagacc acgagctact gtcgtcaagg
     3001 ttgcagtgcc tggttttcta acaccacgca tactcataca catatgttcc gcctcaatga
     3061 caacaaaggc tcctttagca cctagatagt ccatcaaggc atcggccact tcgatattca
     3121 aacgttcttg aatttgtggt tttttcgaat aaacttcaac cgtacgggct agcttagaca
     3181 agcctgccac acgaccatct ggaatgtagg caatgtgcgc tctaccataa aatggcaaga
     3241 agtggtgttc acacatggta tggaaaaaga tatccttttc taccaccata ttatcgtcaa
     3301 taatttcaaa ggattttgac aaatgttcct ctgctgtttg accaagacct gaaaaaatct
     3361 cttgatacat acgggctaca cgagcaggtg tttcctgcaa accctcgcga ttagcgtcct
     3421 ctcctacagc ctcgataatc atttttacag ctgcttcaat cttttgtgta tccattctcg
     3481 ttcttcctct ccatcagata ggccctcact tggctcaaga aatacaagga acctgtgaca
     3541 atcctaactg tttgtttctc ttctttttta tctgtcaaat tctgctctag aaaatcatgc
     3601 caatcttggt agctgagatt tctagactta gctgcctctt tcagcacgct ttcatccgtc
     3661 gcccgactat ccgcaaaatg tgttagagta agctcggtat ctggcatggc tcccagcaag
     3721 tccaacatat cctccaaggc cttggttttg atacaagtga agaggatttc cttatgataa
     3781 tccgcaaaac gttcttgcaa ggttaccaac aaggccttga tagcatgggg attgtgggct
     3841 ccatccaaaa tcatcaaggg atctcttgac acgatttcca aacgccctgg ccaacttgtt
     3901 tcttccaagg cttgaccaag aaagtcattg cttgctagct ctcgaccatc ttcttgacaa
     3961 aaagtatcaa gtaaagctat ggccatccca gcattctcta tttggtacaa accaagcagg
     4021 ctagtctgga agcgaccttg tctgacagca cttgtatagt caaagacttc ccctgtcacc
     4081 acactttctt gatgacgaac ctgataatct gtcccgtagg caagtctcgg cgaatctttc
     4141 ccttccgcaa tgcggtcaat cacagtcaag gcttctggag caatacgccc tgttaccaag
     4201 ggcatccctt gtttgataat acctgccttc tgctctgcta tggcctccaa ggtgtcacca
     4261 agtagggcca catgatccaa gccaatagtt gtaattcctg tcaaaatggg ctgacagaca
     4321 ttggtactat ccaaaagtcc acccatgcca acttccatga tggccacatc tacttgctct
     4381 gaggcaaagt agtcataggc cagggctgtg ataatctcaa actcggttgt gccctgtaaa
     4441 ttggcgaccg cttctccctc cagcaaagac tgatagtctg ccatgagagc ttctagcctc
     4501 gcttctgaga tcgattcccc attgatgcta atctggtctg tgtaatgaat gagatagggc
     4561 gagctaaaca cgccaactct cagccctagc ttttctagca tctttttcaa aaaagcaata
     4621 gtcgagccct tgccgttagt ccctccgata tggaggacct tgagtttgag atggggattg
     4681 ccacgcaaag ctaacagttc caccattcgt tccaagccaa aatgcggttg atccgtccgg
     4741 tagttagcaa tccactgatt gttttcaatt tctttcatct tatttatatt gctttaaatc
     4801 taaattttcc gcttcatcag ccagacgaat ggcagatgca atttcaactg ccatcctgtg
     4861 actagctacg tcatgcacgc gcaccacttc tacaccctgt ctcgcagcga tactagttac
     4921 atgagccgaa gccgtgtccc gatttcggaa accaagctct gtctcaggat tgacttcaaa
     4981 cccactttct tcaaggatat tgatgacaaa tcgcttgcgc gacactccga gaaagattgg
     5041 atagcccttc tgatgtagtt tatccagatc ccgtaaaagg aggagatttt ctttcttggt
     5101 cagaccaaag ccaattcctg gatccaacag gatattttct ggtgcaatac cagcttctgc
     5161 cgctctcgct agtgctcgtt caaagaaagc caccatcaag tcttcgattg gcaatgtttc
     5221 aaagtcagct aactcttcta ctgtaaaagt ttgattaaat ccaaaatgag ggaatatgag
     5281 cgagctaggg tgttgaggtc gcgccataac tggattaaac atgatgacca cttgcgctct
     5341 cgcttcagct accacatgag ccattttttc atcgcccatg agaccagtga tatcattaac
     5401 tagattggca ccagcagcca aagcagcctc tgctacttga ctcttccaag tatcaataga
     5461 gatgaggaca tcactttcct tgcgaatcgc tttgatcact ggaacaacac gctggatttc
     5521 ctcttctatc tcaacatagc tactgcccgg ccgagtcgat tctccgccga tatcgagcat
     5581 actggctcct tctgctatca atttacgagc ctgctggagt gcctgctcaa gagcaaaaaa
     5641 ttgaccaccg tccgaaaagg agtctggggt tacattgata attccgcaaa taactgtctt
     5701 tgcatgattg gctttacttg acatatcggt cactccctca aggattttca tcatattatt
     5761 tttctatttt accataaaaa gaaaaagatg gacacgattg cattcatctt tccctagtag
     5821 aaagaggtcg gtttctacat aaaagctttt aaacagaaat tcctaatgtc cgactcataa
     5881 tcaccacaag agccaacaaa cagaaagcaa tcccattaac aatcatgtga agcaagatcg
     5941 acatttccaa acgttgggtc ttgtaggccg tccaagatag aactgtcgac atacctccat
     6001 aaatcaataa agaaggtaaa ttacttggtt gatgcaataa agcaaacaca atcgtaccga
     6061 ctacaaatcc caagttctcc ttgcctcgga aaatcttttt aggaacaatc ccacggcaca
     6121 agatttcctc acaaatcgga gcaagcaagg ctagcaagaa gaaactggaa atcaacgaac
     6181 tattttgaac catatcgtta atctgagact ggttagctgt tgtcgtctca tttgacagtt
     6241 gcaacaagat agaaccaagt atatttgacc cgacaataac taaataactc aagcccaaac
     6301 gtgccaaatc tttagctcta aaaaaagaaa aattaaaact agctaacttg gttttacgag
     6361 ctcccataat aaatagagcc agaaccacaa ttgaaaggcc agcaactatc agccctgact
     6421 gtagcagggc tacttctttt aaagtcaaaa tagaggtaac cactagggga acctgatata
     6481 aaaggacggc aagtaaaaag accaaaatcc agcctgcacg attcaacaat tctttccaca
     6541 tatttttctc tttcatcacc tatctccttt gtattaaaaa aggggggaaa tccccctggg
     6601 tcattctatt ataaggccat gctgatgtag ttaaggataa acaaggcatc caaaatccaa
     6661 atcatggcat gaacatcttt aacttgacct ttgacaagct tagtcaaagt gtaagtcaag
     6721 aaaccaactg caatcccttg agtgatagag tagctgaatc ccataaagat agatgtgaag
     6781 aaggcaggaa ctgcttcaga catatcatcc caatggatat ttttcaagct accaagcatc
     6841 ataatcccaa cgataatcaa gattggagct gtagccgctg ttggtacgat cgctagaagt
     6901 gggctaaaga agcttgaaat cgcaaaacag atagctacaa ccaaggctgt caaaccagta
     6961 cgtccacctg caccgatacc agcagcagac tcaacataag tcgttacgtt tgaagtacct
     7021 gcaatggcac cgactgtcgt tccaatcaaa tcagagtaaa gagccttatc caatttggct
     7081 gattggtgat tttcaccatt tgtcgctaca ataccaactt tttcacctgt accgatcaag
     7141 gtaccaattg tgtcaaaaat atctgtcaat gagaaggcaa gaatggccat cagagtttca
     7201 ggcaagcgag ctgtatctga aaccaaagct cccaaacctt ctgaaccaag agctgcacca
     7261 aagattgtct tcaaatcttc aaaagctgca ccaacatggt tattagcaaa atcgatacta
     7321 gacaaatcaa ccaaaccaac tgcaatagca agaacagttg ttgtcaagat agagagaata
     7381 attccccctt taatcccttt gatgacaaag aagatagtaa tggcaagtcc tgcaagagcc
     7441 actaaaacag ctggattatt aaagctgacc aatcctggaa ctgctgaaga gtttgctgca
     7501 atcgttgctt gagctttgtc agccccttct cctacaacag tatagttgcc tggatcaatc
     7561 gtgaatttca aaagtccagc attcttaatc cctacatagg caaggaagac accgatacca
     7621 gctgaaatag ctgagcgaag agcattggga atcgattcaa tgatcatttt acgaacattt
     7681 gtcaaggtaa taatcaatga aataatccca cagatgaaga ccatagctag ggcttcttgc
     7741 caagaataac caagcccgaa tacaactgta aaggtaaaga aggcattgag tcccatacct
     7801 ggcgcttggg cataaggtaa gttagcataa aaagccatca tcaaggtacc cgctactgca
     7861 ccaataatcg tcgctaggaa gacgccctga gcaggcattc ctgtttgtga aagtatttgt
     7921 gggtttacaa agagaatata gctcattgca aagaaagttg ttaaaccagc gagaacctct
     7981 gtacgaacgt ctgtaccgtt ctcttttagt ttaaataatt tgtccatcat caatctcctt
     8041 ttaattttta cgaacaataa tagaattata tcatttatca ttcacttttt caatgtattt
     8101 gtttgatttg tttaagaaat taatccaatt tcattttttg tttggaatct gcttttctgc
     8161 ctgctttctg ttataataga agacatctta tctgaaaaca cactagaaag gtccatatga
     8221 cgaaaaaaat tattgcagtt gacctggatg gaaccctgct caactcagac agtcaaattt
     8281 ctgactttac caaaagaacc atcaaaaaag ttgctgaaaa aggccatcag gttattatta
     8341 cgacaggtcg cccttaccgt atgtcaaaag atttttaccg tgaactgggc ttagacactc
     8401 ctatgattaa cttcaacgga tcccttactc atttaccaga ccaagtttgg gattttgaaa
     8461 agtgtttgac tgtagacaaa aaatatctgc tagatatggt tcaacgttca gaggacattc
     8521 aagccgattt tatcgctgga gaatatcgta aaaaattcta cattacaaat cccaatgaag
     8581 aaattgccaa tcccaaacta tttggtgtag aagctttcca gcctgaagat caattccagc
     8641 ctgaattggt gaccaaggac cctaactgta tcctcttgca gaccagagcc agtgacaaat
     8701 atgccttggc aaaagaaatg aacgccttct accagcatca actttctatc aatacctggg
     8761 gaggtccgct caatatcctt gaatgtaccc caaaaggtgt caacaaggcc tttgctttgg
     8821 actacttgct caagataatg aatcgtgaca aaaaagattt gattgccttt ggagatgaac
     8881 acaatgatac cgaaatgctc gcttttgctg ggaagggtta tgccatgaaa aatgccaatc
     8941 cagagctact cccttatgca gatgagcaaa tttcccttac caacgaccaa gatggggttg
     9001 ccaaaaccct acaagactta ttcttataac ctatactgat actcaatgag aatcaaagag
     9061 caaactagga agctagccgt aggttgctca aagcactgct ttgaggttgt agatgaagct
     9121 gacgtggttt gaagagattt tcgaagagta tgaccagctt gcaagctggt ctttgtgctc
     9181 ttttcacagt ctcatcaacc agttaatcga ttgttctact ttttgtctcc aaaaccttgg
     9241 aaaaggcttt cttttgtgat atacttcaca tataaataca agagagctcg tcacactcga
     9301 ctctgttgac aaaaaatcaa tccagtcccg ttgtccctgt tctcggtcaa tatcaaggag
     9361 gatagctatg aaagctgttg ttgtaaatcc agaaagcact ggtgttgcta ttgaagaaaa
     9421 agtactccgt ccacttgaaa ctggggaagc acttgtagaa gttgaatact gtggtgtttg
     9481 ccacaccgac ctccacgttg ctcatggtga ctttggtcaa gtcccaggac gtgttcttgg
     9541 gcacgaaggt atcggtatcg ttaaagagat tgctccagat gtgaaaagcc ttaaagtcgg
     9601 tgaccgcgtc agcgttgctt ggttctttga aggatgtggc acttgcgaat actgtacaac
     9661 tggtcgcgaa accctttgcc gtacagtgaa aaatgctggc tactcagtag acggtggtat
     9721 ggctgaacaa tgtatcgtaa ctgctgacta tgctgtcaag gttcctgacg gacttgatcc
     9781 agcccaagct tcttctatca catgtgctgg agtaacaacc tataaagcta tcaaagaagc
     9841 aaaagttgaa ccaggccaat gggttgttct ttacggtgct ggtggacttg gtaacctcgc
     9901 tgttcaatac gctaaaaaag tattcaatgc tcatgttatc gcagtcgata tcaacaatga
     9961 caaacttgcc cttgcaaaag aagtaggcgc tgacattgtg attaacggcc tcgaagttga
    10021 agatgtagct ggactcatta aaggaaaaac tgatggagga gctcattcag ctgtcgtaac
    10081 tgctgtgtct aaagttgcct tcaaccaggc tgttgactcc gttcgtgctg gtggtcgcgt
    10141 cgtcgctgtt ggtcttcctt ctgaaatgat ggaactcagt atcgttaaaa cagtcctcga
    10201 tggaatccaa gtcatcggtt ctcttgtcgg aactcgtaaa gacttagaag aagccttcca
    10261 atttggtgca gaaggtctgg tagccccagt tgttcaaaaa cgtccagtag aagatgctgt
    10321 tgccattttc gacgaaatgg aaaaaggtca aatccaagga cgtatggtac tcgacttcac
    10381 ccactaatct aatagaaacc tattttaaaa gttggaagct tcttctaact tttttatatt
    10441 aaatttttaa ataagaattc aagattactc cttaaaaact caacatatca acatataaaa
    10501 ataaaaattt tttaattttt tatgataaat agttgctttt tttatgaaaa cggtttatac
    10561 ttaaacagtc ttaaagtttt cttaaatgaa aactaaaaca aaaaaggagg aatgacaata
    10621 atgagtatcg gaatcattat tgcgagccac ggcgaatttg ctgcgggtat tcatcagtca
    10681 ggatctatga tctttggtga acaagaaaag gttcaagttg tgacctttat gccaaatgaa
    10741 ggtcctgatg atctatacgc taagtttaat aacgctgttg ctgcatttga cgcagaagat
    10801 gaggttctag ttttggctga cctttggagt ggttctccat ttaaccaagc tagtcgcgtg
    10861 atgggagaaa atcctgagcg taagtttgcc atcatcacag gacttaactt accgatgttg
    10921 attcaagcct acacagagcg cctcatggac gctgctgcag gtgtagaaaa agtcgctgct
    10981 aatatcatta aagaagccaa ggatggcatc aaagctcttc cagaagagct aaatccagtt
    11041 gaagaagttg caagcgctgc agctgctcca gttgcccaag ctgctatccc agaaggaact
    11101 gttatcggag acggtaaatt gaaaatcaat cttgcccgtc ttgacacacg tctacttcac
    11161 ggtcaggttg caactgcttg gactccagat tcaaaagcaa atcgtatcat cgttgcttca
    11221 gataacgtgg ctaaagacga ccttcgtaaa gaattgatta aacaagcagc tccaggtaat
    11281 gtcaaggcta acgtggttcc aattcaaaaa ctgattgaga tttcaaaaga cccacgtttt
    11341 ggagaaacac atgcccttat cttgtttgaa acacctcaag atgcccttcg tgccatcgaa
    11401 ggcggcgtgc caatcaagac tcttaacgtt ggttctatgg ctcactcaac aggtaaaaca
    11461 ttggtcaata ccgttttgtc tatggacaaa gaagatgttg cgacatttga aaaaatgcgt
    11521 gacttgggtg ttgaatttga tgtccgtaaa gtaccaaatg attctaaaaa agatttgttt
    11581 gacttgatta acaaagccaa tgtcaaataa gccattattt atgaaaggat tttaaacatg
    11641 tctattattt ctatggtttt agtagtcgtt gtagccttct ttgcaggtct tgaaggcatc
    11701 ctcgaccagt tccaatttca ccaaccactt gtagcctgta cccttattgg gcttgtaaca
    11761 ggtcacttgg aagcagggat tatcctcggt ggatcgcttc aaatgattgc ccttggttgg
    11821 tcaaatatcg gtgctgctat cgctcctgat gctgcacttg cttctgtcgc tgctgccatt
    11881 atcatggttc ttggtggtga ctttaccaag actggtatcg gtgttgccca agcggttgct
    11941 atccctcttg ccgtagctgg acttttcttg acaatgattg ttcgtacaat ttcagttggt
    12001 ttggttcata ctgcagatgc tgccgctaaa aaaggtgact tcggcgctgt ggagcgtgcg
    12061 catttcattg cgctactctt ccaaggactt cgtatcgcgc ttcctgcagc tcttctcctt
    12121 atggtaccaa ctgaaactgt acaaagtatc cttagtgcca tgccagactg gctcaaagat
    12181 ggtatggcta tcggtggtgg tatggtcgtt gccgttggtt acgccatggt tatcaacatg
    12241 atggcaactc gtgaagtatg gccattcttc gctcttggtt tcgttctcgc tgctgtgtca
    12301 gatattactc taatcggatt cggtgctatc ggtgttgcta tcgctcttat ctaccttcac
    12361 ctttctaaaa ctggtggaaa tggtggcgga ggagccgcaa cttctaacga cccaatcggc
    12421 gatatcctag aagactacta agataagaaa ggactgaaaa catcatgact gaaaaacttc
    12481 aattaactaa atcagatcgt aaaaaagttt ggtggcgttc aaccttctta caagggtctt
    12541 ggaactttga acggatgcaa aacttgggct gggcttatac actcattcca gctatcaaaa
    12601 aactctatac taaaaaagaa gatcaaatcg ctgctcttga gcgtcacctt gagttcttca
    12661 acactcatcc atacgtagct gctccagtca tgggggttac tcttgcgctt gaagaagaac
    12721 gtgctaacgg tgtggaaatc gatgacgctg ctatccaagg ggtcaaaatc ggtatgatgg
    12781 gacctcttgc tggtatcggt gacccagtat tctggtttac agtacgccca atccttggat
    12841 ctctcggtgc ttcacttgcc cttactggca atatcttggg tccactcctc ttctttgttg
    12901 catggaactt gattcgtatg tcattcttgt ggtatgttca agagattgga tacaaggctg
    12961 gatcagaaat cactaaagat atgtctggtg gtatccttca agatatcact aaaggagctt
    13021 ctatccttgg gatgttcatt cttgctgtcc ttgttcaacg ctgggtaaat attaaatttg
    13081 ctttcgatgt ttctaaagtt caactagatg aaaaggctta tatccattgg gataaattgc
    13141 cagaagggtc taaaggtatc caagaagcat tcgcacaagt aggacaagga ttgtctcaaa
    13201 ctcctgaaaa agttactact ttccaacaaa acttggatat gttgattcct ggattatcag
    13261 gactactcct tactttactt tgcatgtact tacttaagaa aaaagtatct ccaatcacta
    13321 ttatccttgc cctcttcgca gtgggtattg tggcacatgt tcttcacatc atgtaatcaa
    13381 gcaactaaaa aggaaccagg ttctaaaatc tgattccttt tttctatgct tttattcagc
    13441 caaggctccc attggatccc atggtgcaag tacaattggt tctgctccat aggcagcttg
    13501 ttcttctgct gtcagcaatt ccttacgaac aacgatttgg tatgtgtatt cgtccatcca
    13561 agcgtctgag gcaacaaagt aaccatctgt accgaccttg tctccccatg agttttcaac
    13621 cttccacttg gttgatttac cattttcgtc caagtcaaca cctgtcaaga ccatggcgtg
    13681 ggtcatcaag ctttcgctat agtccaaacg tccagccttg tcttgagtaa gtttaatgtc
    13741 catgcttgat tcaaagtcat aaacatctgt cgcaaggatg ccagccttac ggttactgag
    13801 ctggccgaca tcagaaccaa accaaacagt ctcacctgct tgcatttggg caatcgccaa
    13861 ttctttcaag cgctccattg gaacgttgat gtaacgaact gcacggctac caaccacatt
    13921 ccccaacatc tcaactgtgt aagattttcc gtaaggttta tcagcagttg gagcattgat
    13981 aacagaaacg tagtcttcta aaggaagatt gacatatttc ttgtaaaact cttgtggtgt
    14041 gattcctttt tcacttttgt agttgttatc tttatcgcga taagcaaagt caaacttgcg
    14101 tggtggaagt cctaatgaca tagcaagaaa gttaaagatt tcttgcaaga ggtcttcttt
    14161 cttagcttga acagtcgctt gatctgcacc agaaacaagc aagtcacgca agatttgagc
    14221 atcttgacga agcaatttat taaggatcgc atttagctca cgactgctgc tagatgaaac
    14281 agactcagga taaactgact taggcacgac accgtatttt tcaaagaggg aaacgaccat
    14341 atcccattga ccaccatctt gttgaggtgt ttggagtaag aagctaacct tgcggctagt
    14401 caattcttgg tctgaagtcg caatgacttg ctccaagaac cagtttgatt tctcatactt
    14461 atcccagaag aaagtgtggg cttgtgacaa ctcaaagttc tccaatttgt attgcgagat
    14521 gagtttgtgg cggaaggtgt tgagagccgc aaacatccag caacgaccag acgctttctg
    14581 gttagtgacc ttgtccttgg ttaaatccaa tgagaaaaca ggtgtgttgt ctacatggct
    14641 ttggcgacgt tccagagctg caaaaattcc gttgtggcta gcagcatttt caatcgcttg
    14701 gtattttaca tttgcttcat agttggcaaa tagtttatca gtaaatgatt cttgaatcgc
    14761 gttcatagat tcctcctttt attctacagt ctattataac tcttttcaca aaggaagcaa
    14821 ctaaaaaaca taaaaggtaa ggacattctc cctcaccttt ttcgaatata tactcttcga
    14881 aaatctcttc aaaccacgtc aacgtcgcct tgccgtactc aagtacagcc tgcggctagt
    14941 ttcctagttt gctctttgat tttcattgag tattaaacta aattaaataa tattagcgcg
    15001 gagaatttct aattcttcct tggtcaagcg acgccattcc cctcgttcca ggttctcatc
    15061 taatactaaa gttcccatag tcaatcgttg caagtccacc acttccttgc cacagtagcc
    15121 caccatacgc ttgatctgat gaaacttccc ttctgcaatg gtcacacgga tttggctttg
    15181 attcttttct gtatctatgg atacaagctc cagtatagcg ggtttacagg taaagtcttt
    15241 gagaggaata ccctcagcaa atgtctccac atcttcttgg gtcatgattc ccttgacttg
    15301 tgccagataa gtcttgtcca catgacgctt gggcgaaaga agaacatgag ccagctgacc
    15361 atcattggtc aagagcaaaa gaccatgcgt gttaatatcc aagcgtccta ctgggaaaac
    15421 ttccttactc cgcgccaagt catccaacaa gtccagaacg gttctgtgct tgggatcctc
    15481 agtcgctgag ataactcctt tgggcttgtt catcatgtag tagacaaact cttcatactc
    15541 caacacttgc ccatcaaagc gaatctcatc tattttttca tcaatctgca atttagctga
    15601 tttttctttt ttaccattta cagtcacgcg cccagccttg agcaagtttt tgacctcagt
    15661 ccgacttccc accgcacagg caactaaaaa tttatctaat ctcatagaac tattatatca
    15721 tatcaaaagg aggctggtac aatgaccaac ctccttttcg tttcatactc ttcaaaaatc
    15781 tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtt actgacttcg tcagttctat
    15841 ctgcaacctc aaaacagtgt ttttagctga cttcgtcagt tctatctgca acctcaaaac
    15901 agtgttttta gctgacttcg tcagttctat ctgcaacctc aaagcagtgc tttgagcaac
    15961 ctgcggctag tttcctagtt tgctctttga ttttcattga gtatcagatt taggaaatta
    16021 acttcctcgt ctccaaaaaa tagctaagac aatcatggca cctaaaacag ctgggataat
    16081 agctgttcct gataaaactg gcccccaagt tccaaagagc aagtgaccta gaaaggctcc
    16141 gatccaaccg agaaacattt ttccaaaaca tcccattcgc tctccacgat tggtcatagc
    16201 acctgctaaa aatcccacta ggagaccaac gaacatactt cctaacatat tatctcctta
    16261 atttgcccaa ttcccattac ggaaaagagg tacccgcgtt ccatcctcac gaataccatc
    16321 gatatccatt tggttagaac caatcataaa gtctacgtga acatctgaac ggttaagccc
    16381 tgcagcttca agctcctctt cgctcatctc cgctccatca acaaggctag tcgcataggc
    16441 tgcaccgata gccaagtggt ttgacgcatt ttcatcgaaa agggtgttaa agaaggtaat
    16501 gcctgactga gaaattggac ttggatctgg taccaaggca cattcaccca aggcacgcgc
    16561 acccgcattt tcaaagacaa ggtctttcat aacctgatca cccttctcag cagtgatatc
    16621 tacgatttgt ccatccttaa agatcacctt aatgccttca atgatatttc cgttgtagct
    16681 aagcggtttt gtagaagtga cataaccatc tgcacgacgg aagtcaggcg ctgtgaagac
    16741 ctcttctgtc ggcatatttg gcaagaatcc ttcgccctgt gcattgacag caccagctga
    16801 ttcccaaacg tggttctttg gcaaaccaag tgttaaatct gttcctggcg ctgtgtagtg
    16861 aagggctgaa aattgctcct tattaagcat atcggccttg ctcttgagaa tggctgcatg
    16921 ctcttcccag gccttaacag gatctgcttc gtagacacgg caagttttga agatttggtc
    16981 ccaaaggaga tcgactgctt cttcgtcgct cgcagcattt gggaagactt tcttagccca
    17041 ctcaagtcca gcagcggctg ctacagtcca gctaaccttg ttagattgag ttgcgattcg
    17101 cattggcttc atggcaagtc ccatagcttt agcagaagct gaaagcttgt cagcgtccac
    17161 tccgttcaag gcacctggat cagatgaacg aactccaaga cggctagcct tgttctccaa
    17221 gagatagttc atctcagcaa tcttgtattc tggcacattg tccaaacgct ccatcggggc
    17281 atggaggaat ttctcacggt taatcacatc atctgtccac tgaacgatga cctcatgcgc
    17341 acccaaggca taagcttctt tcacgattag atgtgccaat tcacgttgct ccacatcaat
    17401 agagagagcc aaagtgtgac caggttgcac gttaattccg ttcgcaacca acaatttcgc
    17461 atatttttct agattttctt taaaatttgg taaaaccatc ctgttttctc ttttctattt
    17521 ttatttttct ttcaaagcag aaaagattcc tgctaaagca atagcacctg acaagagtgc
    17581 tgtcgataaa agaattgtac gatcagcaag ttctaattga tattcaaata ccttcttagc
    17641 cggcttatct tccgcaaata ttcttagttt catgagaacc cccttaaaat agattaaaat
    17701 aaatcactgt gactgcctgt cctcagcaaa tttaaaatca attccgactt atctacttta
    17761 taaaccaaaa gccaatctgg ctgggtatgg cattcacgaa ctccttgaaa atgcttggat
    17821 gccgtcaatg aatgatcacg atatctggca ggatgttctt tttcttgaac cagaaaattc
    17881 aaaacttctt ctaataattc tgccttcaaa ccacgcttca tagccaactt aaaatctttt
    17941 ttaaactgtt tatgataacg aatcttaagc acgtaagtcc tccatcaaat ctgagactga
    18001 ttcaaaagac tggctcatat tacgattttg gtctaaatcc gttaacactt ggagcaactt
    18061 ccgattttcg tctagtctaa catcaaaagg taatccctga tattgaattg cctgacgaag
    18121 gaaaatatta atagctgttg tcatatccat tcccagatta ctaaacacct gttgggcctg
    18181 ctccttaacc tcactatcca gacggatgct catactcatc tttgacatac tctcaccctc
    18241 tttccataga ctattttaac aaaaaagaaa gctaatgtaa atctattgga tatacgttag
    18301 cctcttctaa tagattatta agcaattttt taaaacaact catcaaacaa actcaactgg
    18361 ttatcctctg gcatatttcc aagaataccc atctcatcca tcttttcaac caaggttgat
    18421 gagagtccac cacgcttgcg tagttctgtt ttagagagga attctccctc ttcacgcgcc
    18481 cgcaccagtt gcttggcaac gttctctccc agaccatcca ttgctacaaa tggtgggata
    18541 agggtatccc cgtcgatgag gaactctgtc gcctgactac ggtagagatc taatttgcca
    18601 aacttgaaac ctcgttccca catctcattg acaatctcaa gagttgtata gagatcgatt
    18661 tccacattag aggcttcatt gttcttccgt ttttcagaga tttcttccat tctgcgcttg
    18721 atggcctcca agcccgcacc catggtcttg atatcaaaag ccttagcacg aatggagaag
    18781 taagcacagt agtaataaat aggatggtga accttgaagt aagctacacg caaggccatc
    18841 ataacgtagg ctgccgcatg ggccttaggg aacatgtact taattttccc acaggattcg
    18901 atataccact ctggcacctt attagccttc atggcttcga tatagccatt tctctcctct
    18961 tctgaaatct ttagccacaa acccttacgt acccgttcca taatggtaaa ggccatctta
    19021 ggttccagac ccgcatgcat gaggtaaacc atgatgtcgt cccgacaacc gataacagtc
    19081 gataggtccg ctattccttg cttaatcaga tcctgagcat tccccaacca aacgtcagta
    19141 ccgtgggaca gaccagacag ctgaagcaat tccgcaaagg ttgtcggatg ggtttcgtct
    19201 accattccac gtacgaaatt tgttccaaac tctggaatcc ccaacatacc cgtaggcgtt
    19261 ccaatttgtt caggtgttac ccctagcaca tcagtcccag aaaagagtgc catcacgcct
    19321 tcgtcatcca taggaatttc attagggtca ataccagaca aatcctgaag ttttcgaatc
    19381 atggtcggat catcatgtcc cagtacatcg agtttgagga cgttctcatc gatatcgtgg
    19441 aagttaaagt gagtggtctg ccattcagcc gtgacatcat ctgctggata ctggacaggc
    19501 gtaaaatcgt agacatccat gtagttcgga ataacaacga ttccccccgg gtgttggcct
    19561 gttgtccgct tgacacccgc cgctccttga gcgaggcgtt ctacttctgc atcacgataa
    19621 aacttgccat aatctcgctc gtaacccttg acaaatccat aggcagtctt ggcagctacc
    19681 gtaccaaccg ttcccgcacg gaaggcatat tcttcaccaa agatatcacg cacatccaag
    19741 tgggcgctag gctgatcttc tcccgagaag ttcaagtcaa tatcaggaac cttatcccca
    19801 tcaaagccaa ggaaggtctc aaacggaata tcctgtccgt ttttactgag tttgtgacca
    19861 cagtttggac agtccttatg gggcatatca aatcctgaac cgtacgaacc atctgtgata
    19921 aactcactgt actgacactg accacagaca tagtgaggag agagaggatt gacctccgta
    19981 atcccaatca tggtcgcaac gaaactagat ccgacagacc cacgagaacc aaccaaataa
    20041 ccccgttcat tagaacgttg caccagcatc tgcgatgcca gataaatcac agcaaatcca
    20101 ttccccagta tggatgttaa ttctttttca atccgcaaat caacaatatc tggcagcgga
    20161 tttccataaa tctcaaaagc tttcttatag gtcaactcag caactgtttc ttcagccttg
    20221 tcgatgaaag gcgtatacaa gtcaccctta acgacttcaa cgggttcaaa tatttctgcc
    20281 aaggcattag tgttttcaat aaccagttta cgagccagtt cctctcccaa aaaggcaaat
    20341 tcatccaaca tctcattagt cgttcgaaaa tgagcctttg gaagtggtgc tggttgggca
    20401 tgttcaccat gaccgatagt tcgattaatc atcgcaccct gtcccaaact acggacaata
    20461 atttcacgat aaatctcttc ttccggttcg atatagtgaa catttcccgt agccagaaca
    20521 ggcttgccaa ggcgatctcc aacctctatc aaactcttga taatggtctg gagttcctcc
    20581 atatccttga cctgctcttt ggcaatcaag ggcgcataga tagccggtgg catgacctcg
    20641 ataaagtcat aatacttggc cacctcaacc gccccatcca caccttgaga aacgaccacg
    20701 tcaaaaactt caccctctga acaggctgaa cctaaaatca agccctctcg atgggcatct
    20761 agaaccgttc tcggaatccg tggcactcct tcaaaatact tggtattaga caaggaaacc
    20821 agcttaaaga tattttttag acctacctga ttcttgacat agatggtcgc atgcttgatc
    20881 cgagcttttt tgtaagaatc tggactgatt agatcaatgt tgagtctagc taaatcggtc
    20941 acaccatgtt tttctgctac ctctttgata aagatgaaaa gcagacgacc agtcgcttcc
    21001 gcatcgtaat tggccatgtg gtgatgttcc aaggccacac caaaacgctt ggtcaaaggc
    21061 cccaaaccat ggcgtttata ctcaggatag aggtttctag caaactccag cgtatcaata
    21121 actggctgac taatctttgg aagaccatga cgctcataat tagcattcat aaagccaacg
    21181 tcaaaggtag cattgtgggc aactaggacc gtatccttgc aaaattcttg gaattcttgc
    21241 aaaacttgtt ctagtggttt ggcatttttg acatgatcat ctgtaattcc agttaactct
    21301 gtagtaaagg ctgacaaggg atgcccagga ttgataaatt catcaaattc agcaataaca
    21361 ttccccttgt acatcttaga ggccgcaacc tgaatcaagt cattatagat agctgaaagt
    21421 cccgtcgttt ccacgtcaaa gaccacgtag gttgcttctg acaagtccat ctccacttcg
    21481 ttatagacga tagggacacg gtcctccacg atattggctt ccatcccata gatcagctgg
    21541 attcccgctt tcttagccgc cttatagcca tgtggaaagg actggacatt cccatggtcc
    21601 gtgatagcaa ccgccttgtg tccccactta gcagctgttg caacaatctc ttcgacctct
    21661 ggcaaagcat ccatagtcga catgttagta tgagcatgaa actcaacccg acgctcacct
    21721 tctggcatca aatccttccg ctcatagtga acaacttcct gcagatcctg tacgttcata
    21781 gtcaaatcgc gtgtgaagtt attcatctcc acattccctc gaactcggag ccaagaattc
    21841 ttcttgatga gatcaaactt ctgggcctct tcctcgtttt taacccactt ttgcatagaa
    21901 aaacttgaag tgtagtccgt cattttaaag ttgattaaaa cacgacctgt tctagtcact
    21961 ttttgctcca catcaaaaac aaccccttca aataccagac gattttcctc tgtcgtcact
    22021 tcgatcatag gagtaatctc cgccttatcc agcttgggtt tagctgcagc ttttttcgct
    22081 tgaaaatcaa agactggttt ctcttccgct ggaggaggtg ccatctgctc cagttgttcc
    22141 atagcacgga gcgcttcctc attggcagct tgaacaatct gctcattttc agcatgaaag
    22201 gcctcttcct gctcttgggt caggacatca ttcttatcga cttgacagtt aaaagttgga
    22261 aaaccaaact tttcaagttg tttggctaaa ttaggaagat gattcttctt aaaatgttcc
    22321 ttatcaatcg cctcagatcc ttcaataaat agctgattac cctcagcacg aacttgcaaa
    22381 ttttgataaa gggacttaaa accttgacta gcacatggac cttcagagaa agcctcccta
    22441 tagtaggact gcaagagctg atttgaaaat tcttgagacc gagccttaat ttcaaaaaca
    22501 gctttattgc ctgtcttaga aaattcttcg ctcaaacctt tctttaattc taaaaagatt
    22561 tcaatcggta aaatattaga aaatacgaaa tgaaactccc ataccttact aattttatga
    22621 accacaactc gctcaatatt ggcctgtgct aaagcaggag cctgtctcat ttcagcaggc
    22681 atccccaatt gattcatcaa aatttcaaaa ctatttgaca ttcattttcc tcacattatt
    22741 cttctactat tttaccatat ttagaggtat tttctaaaga caaaaggaag ccactaagtg
    22801 acttccttct agagtgagga cggattagtc ttcaccttta tttttcttaa taatttcttc
    22861 ttgtactgac ttaggtacat cttcgtagtg gtcaaatacc atcatgaatg taccacgtcc
    22921 ttgagatgca gaacgaagaa ctgttgcgta accgaacatt tcagcaagtg gaacgtaagc
    22981 acgaacgatt tggctgttac cgtgtgcttc cataccatct acacgtccac gacgagcagt
    23041 tacgtgaccc ataacatcac caaggttttc ttctggaaca gtgattgtta caagcatcat
    23101 tggttcaagg atagctggtt gtgctgattt agcagcttct ttaagggaaa gtgaagccgc
    23161 aatcttgaag gcagtttcag atgagtcgac atcgtgatat gaaccatcat aaagcttagc
    23221 tttaacgtca accattgggt aacctgcaag aacaccgtta gccatagatt ctaccaaacc
    23281 tttttcaacc gctgggataa attcacgagg aaccacacca ccgacgattg cgttttcgaa
    23341 ttcgaatcct ttaccttctt cgtttggagt aaattcaatc cacacatcac cgaattgacc
    23401 tttaccacca gactgacgtt tgaagaatcc acgtgcttga gtagaagcgc ggaatgtttc
    23461 acggtaagat acttgaggcg cacctacgtt cgcttcaact ttgaactcac gacgcatacg
    23521 atcaacaagg acgtcaaggt gaagttcacc catacctgag ataactgttt caccagtttc
    23581 aacgtttgtt tcaacgcgga atgttggatc ttcttcagcc aatttttgaa gggcgatacc
    23641 catcttgtct tggtcagctt tagattttgg ctcaaccatc aattggataa ctggttctgg
    23701 aacgttgatt gactcaagga tgattttaga tttttcatct gtcaatgagt caccagttgt
    23761 agtatctttc aaaccaacgg cagcagcgat atcacctgag taaacagtgt cgatttcttg
    23821 acggctgtta gcgtgcattt gaaggatacg tccgatacgt tcacgtttac ctttagaagt
    23881 attcaatacg tatgaacctg attgaagaac acctgagtaa acacggaaga atgtcaaacg
    23941 acctacgaat gggtcagtca tgatcttgaa ggcaagagct gcaaatggct cttcgtcaga
    24001 tgctggacga gtttcttcag cgtctgtatc tgggttaata cctttgattg ctgggatgtc
    24061 aagtggactt ggaaggtagt cgataaccgc atcaagcatc aattgaacac ctttgttttt
    24121 gaaggctgaa ccacacaata ctgggaagaa ttcaacgttg atagtcgctt tacggatacc
    24181 agctttcaat tcttcgttag tgatttcttc accttcgagg tatttcatca tcaattcttc
    24241 gtcagtttca gcaactgctt caatcaattt ttcacggtat tcttgagctt ggtcaaggta
    24301 ttcagctggg atgtcttctt caaggatatc cgtaccaagg tcgttagtat agatttcagc
    24361 tttcatcttg attaagtcaa tgataccacg gaagtcatct tcagaaccga ttggcaattg
    24421 gattgggtgt gcatttgctt gaaggcgatc gtgaagtgtg cttacagagt aaaggaagtc
    24481 agcaccgatt ttgtccattt tgttggcaaa tacgatacgt ggaactccgt actcagttgc
    24541 ttgacgccaa actgtttcag tttgaggctc aacacctgat tgtgagtcaa gaacggtaac
    24601 cgcaccatcc aatacacgaa gagaacgttg tacttcgatt gtgaagtcca cgtgtcctgg
    24661 tgtgtcgatg atgtttacgc ggtggttgtt ccattgagct gttgtcgcag cagatgtgat
    24721 cgtgatacca cgttcttgct cttgctccat ccagtccatt tgtgacgcac cttcgtgagt
    24781 ttcaccgatt ttgtggattt taccagtgta gtaaagaata cgctcagtag ttgttgtttt
    24841 accggcatcg acgtgagcca tgataccgat attacgagtt ttttcaagtg aaaattcgcg
    24901 tgccatgagg tttgtttctc ctatttattt ttgatttcta ttctattata acacgatttt
    24961 aataaaaacg gataggcagg acctacccgt tctcaatgtt ttcatgctat tgttggtttc
    25021 aacttacgag atggtaagct gagttatagc taatactaat cgatttagct aatttgaacc
    25081 cgggctaaag ttagttagcc gatgtgagct ggaacgggat gctgcgtgaa aaagataaaa
    25141 ctccttgtat tcgtcgaata ctgcgtcagt ttcctatttt caccttgcat ccttaccgtt
    25201 cctagcatca tgatttagtt gagctcaagc taaaagtctg gagaaaaaga tgaatctcat
    25261 tggttgcaac cgcaacctgc ttcgattccc tattttctct gggactttct taacgctttc
    25321 gcatcctatc ttaccaacgg aagtgtgcga atgcacggtt agcttcagcc atacggtgag
    25381 tatcttcacg tttcttaact gctgcaccag tgttgttagc agcatccaag atttcttttg
    25441 caagacggtc ttgcattgtg tgttcaccac gaagacgagc gattgttacc aaccaacgaa
    25501 gtccaagtgt tgtacgacgt tctggacgaa cttcaactgg gacttggtag ttagaaccac
    25561 caacacgacg tgcacgtact tcaagtacag gcatgatgtt ttccatagct gtttcaaata
    25621 cttcaagtgc atcgttgcca gtagcttctt tgatttgctc aaaagcaccg taaacgattg
    25681 aagcagcagt accacgttta ccatcaagca taacgcggtt gataagacga gtaactagtt
    25741 gtgaattgta tagcggatct ggcaatacgt cacgttttgg agctctattt ttacgactca
    25801 tttctcttta tcccctttcc ttatgctttt ggacgtttag taccgtattt agaacgacct
    25861 tgtttacgat cgttaacacc tgcagtatca agtgcaccac ggacgatatg gtaacgtacc
    25921 cctggaaggt cttttacacg tccaccgcga agaagcacca cgctgtgctc ttgcaagttg
    25981 tgtccgatac ctgggatgta ggcagtaact tcgataaggt tgctcaaacg tacacgagcg
    26041 aatttacgaa gggctgagtt aggtttttta ggtgtcattg ttccaacacg agttgcaaca
    26101 ccacgttttt gtggtgaaga aacgtttgtt tgaacttttt tatgactatt gtaaccaacg
    26161 ttcaaagctg gtgatttaga tttttctact tttgatttac gcggtttgcg aaccaattgg
    26221 ttaattgtag gcatctacat tctcctgtgt ttttttattt ttggtgatga tacacttggt
    26281 gacagatatc atctgtgtgt acttttgcaa catttgtcag cacgtccctg tacactcttg
    26341 agagaccaaa agtaaaaagt accgtctatt attgtaacaa aattttccct tgtttgtcaa
    26401 gatatttttc ttttttattg gtaatgttag agatcaattt ctgaataaaa atagctggga
    26461 acacatcatc ttcctaataa tacggcttgg cttatgtgac atttttatct ccgtcattta
    26521 tactgatata taaaatagta cagaaaactt ctcaaaagta agaatttttt tcacaaatca
    26581 aagaaaacgc ttgcatattg ttttactaca tgctatactg atatagaaat ttattgattg
    26641 gagaatcatt atgagaaaaa caccatctca cactgagaaa aaaatggtct acagcatccg
    26701 ttccctcaaa aatggaactg gttctgtcct tatcggcgca agccttgtct tgcttgccat
    26761 ggctacacca actatctcat ccgacgaaag tacaccaacc actaacgaac ccaacaacag
    26821 aaatacaacc acccttgccc aacctcttac tgatacagca gctggctctg gtaagaacga
    26881 aagtgatatt tcttcaccta gaaatgcaaa cgcttcccta gagaaaacag aagaaaaacc
    26941 tgcaacagag ccaactactt ctactagtcc agtaacaact gaaactaagg cagaagagcc
    27001 catcgaagat aactacttcc gtatccatgt caaaaaactt cctgaagaaa acaaggatgc
    27061 tcaaggacta tggacttggg acgatgttga aaaaccatct gaaaactggc caaacggagc
    27121 tttgtccttc aaggatgcca agaaagatga ctacggctat tacctagatg tcaaattaaa
    27181 gggagaacaa gccaagaaaa ttagcttcct catcaacaat acagctggaa aaaatctaac
    27241 cggcgataaa tctgtagaaa aactagttcc aaaaatgaac gaggcttggt tagaccaaga
    27301 ttacaaggtt ttctcttacg agccacagcc tgcaggaact gttcgcgtca actactaccg
    27361 cacagatggc aactatgaca agaaatctct ctggtactgg ggagatgtga aaaatccaag
    27421 tagcgctcaa tggcctgacg gaacagactt tacggctaca ggcaaatatg gccgctatat
    27481 cgacattcct cttaatgaag ccgcaagaga atttggattt ttattactag atgagagcaa
    27541 acaaggagac gacgtgaaaa tccgtaaaga aaattataag ttcacagatt tgaaaaatca
    27601 tagccaaatt ttcctaaaag acgatgatga atcgatttac acaaatccat actatgtcca
    27661 tgatatccgt atgacaggag cccaacacgt aggcacttct agcattgaaa gtagcttttc
    27721 aacacttgtc ggtgctaaaa aagaagatat cctcaaacac tccaacatca ctaatcacct
    27781 aggaaacaag gtaactatta ccgatgttgc aatcgatgaa gctggtaaga aagtgaccta
    27841 cagcggagat ttctctgaca caaaacatcc ttatactgtt agctacaatt ccgaccaatt
    27901 cactaccaaa acaagctggc acctgaaaga tgagacatac agctatgatg gcaaactggg
    27961 agctgaccta aaagaagaag gaaaacaagt tgatttgacc ctttggtcac caagtgctga
    28021 taaggtttct gttgttgtct acgacaagaa tgaccctgac aaagtagttg gaactgtcgc
    28081 tctcgaaaaa ggggaaagag gaacttggaa acaaactcta gacagcacaa acaaactcgg
    28141 aatcacagat ttcactggct actattatca ataccaaatc gagcgtcaag gtaaaactgt
    28201 tcttgcactc gatccttacg ctaaatctct tgctgcttgg aatagcgacg atgccaagat
    28261 tgacgatgcc cataaagtgg ctaaagccgc ctttgtagat ccagctaaac tcggacctca
    28321 agacttgact tatggtaaga ttcacaattt caagactcgt gaagacgccg ttatctacga
    28381 agctcatgtg cgtgacttca cttcagatcc tgccattgca aaagacttga ccaaaccatt
    28441 tgggactttt gaagccttca ttgaaaaact agactatctc aaagacttgg gtgtaaccca
    28501 tatccagctc cttccagtct tgtcttacta ctttgtcaat gaattgaaaa accatgaacg
    28561 cttgtctgac tatgcttcaa gcaacagcaa ctacaactgg ggatatgacc ctcaaaacta
    28621 cttctccttg actggtatgt actcaagcga tcctaagaat ccagaaaaac gaatcgcaga
    28681 atttaaaaac ctcatcaacg aaatccacaa acgtggtatg ggagctatcc tagatgtcgt
    28741 ttataaccac acagccaaag tcgatatctt tgaagaccta gagccaaact actaccactt
    28801 tatggatgcc gatggcacac ctcgaactag ctttggtggt ggacgcttgg ggacaaccca
    28861 ccatatgacc aaacggctcc tagttgactc tatcaaatac ctagttgata cctacaaagt
    28921 ggatggcttc cgcttcgata tgatgggaga ccatgacgcc gcttctatcg aagaagctta
    28981 caaggctgca cgcgccctca atccaaacct catcatgctt ggtgaaggtt ggagaaccta
    29041 tgccggtgat gaaaacatgc ctactaaagc tgctgaccaa gattggatga aacataccga
    29101 tactgtcgct gtcttttcag atgacatccg taacaacctc aaatctggtt atccaaacga
    29161 aggtcaacct gcctttatca caggtggcaa gcgtgatgtc aacaccatct ttaaaaatct
    29221 cattgctcaa ccaactaact ttgaagctga cagccctgga gatgtcatcc aatacatagc
    29281 agcccatgat aacttgaccc tctttgacat cattgcccag tctatcaaaa aagacccaag
    29341 caaggctgag aactatgctg aaatccaccg tcgtttacga cttggaaatc tcatggtctt
    29401 gacagctcaa ggaactccat ttatccactc cggtcaggaa tatggacgta ctaaacaatt
    29461 ccgtgaccca gcctacaaga ctccagtagc agaggataag gttccaaaca aatctcactt
    29521 gttgcgtgat aaggacggca acccatttga ctatccttac ttcatccatg attcttacga
    29581 ttctagcgac gcagtcaaca agtttgactg gactaaggct acagatggta aagcttatcc
    29641 tgaaaatgtc aagagccgtg actatatgaa aggtttgatt gcccttcgtc aatctacaga
    29701 tgccttccga cttaagagtc tccaagatat caaagaccgt gtccacctca tcactgtccc
    29761 aggccaaaat ggtgtggaaa aagaggatgt agtgattggc taccaaatca ctgctccaaa
    29821 cggcgatatc tacgcagtct ttgtcaatgc ggatgaaaaa gctcgcgaat ttaatttggg
    29881 aactgccttt gcacatctaa gaaatgcgga agttttggca gatgaaaacc aagcaggatc
    29941 agtcggaatt gccaacccga aaggacttga atggactgaa aaaggcttga aattgaatgc
    30001 ccttacagct actgttcttc gagtctctca aaatggaact agccatgagt caactgcaga
    30061 agagaaacca gactcaaccc cttccaagcc tgaacatcaa aatgaagctt ctcaccctgc
    30121 acatcaagac ctagctccag aagctagacc tgattctact aaaccagatg ccaaagtagc
    30181 tgatgcggaa aataaaccta gccaagctac agctgattca caagctgaac aaccagcaca
    30241 agaagcacaa gcatcatctg taaaagaagc ggttcgaaac gaatcggtag aaaactctag
    30301 caaggaaaat atacctgcaa ccccagatag acaagctgaa cttccaaata caggaatcaa
    30361 aaacgaaaac aaactcctat ttgcaggaat cagcctcctt gcgctccttg gtctcggttt
    30421 cttactaaaa aataaaaaag agaactaaac tagccctcct atagaaaaat cccccaagca
    30481 ttatagctcg ggggattaat tttcgtacaa tatttgttgt cctaataaac ttgattagga
    30541 ttttttatta agcctctttc atagcaaaat aagctcgtac ttttggtgca acttgtgttc
    30601 cgaagagttc aatagctctc agaacctggt catgaggcat agaaccaagc ggtatatgaa
    30661 gcatgaagcg gtccaatcct aaatcctcta tcatgcgaat caatttttcg gccacctgat
    30721 ctggattgcc aacaaacatg gcgccatttg gccctacctg ctccaaatat tgctcataac
    30781 gcaattcctg ccagtgcgga cggtctttgg aaatagcatc caccacttgc ttagtcggat
    30841 ggaaataatc tttcaccgcc tgctcaccat cttccgcaat ccacccccaa gaatgggctc
    30901 ccactttcaa gtctttgtca gcatggcccg cttcgcttcc aatctcacga taagcctgaa
    30961 tcaacttttt aaaataacgt ggattaccac caataatagc atatacaatc ggtagaccag
    31021 cctgagcaat cttcactgtt gattcgacat gaccacctgt agctatccac aagggcaatt
    31081 tgtcctgaac tggacgagga taaacttctt taccagcaat cgtttgagtc aatcgacctt
    31141 gccagtctaa cttggtcttt tcattgacta actgaagcaa gtctaatttc tcatcaaaaa
    31201 gagagtcgta gtctttcaag tcataaccaa acagagggaa agattccgtg aaagagcccc
    31261 ttccagccat aatctccgat cgtccatctg acaaagcatc gatagtggca tactgttgga
    31321 acaaacgaat cgggtccatg cttgacagaa tgctgactgc actggtcaaa cggattttct
    31381 tggtattgac tgccccagcg gccaggacaa tctctggggc tgatactgca aaatccgccc
    31441 gatggtgctc gccaatccca tatacgtcca aaccaacctt gtcagccagc tcaatctctg
    31501 ccaccaactg gcgaatgcgt tcagcatgac tgtaagtttg tccagtccct tcaagctccg
    31561 ttatttcccc aaatgttgaa attcccaatt ctaccattgt gattctcctt gtctatctct
    31621 gtacttcaat ttgaaaaatt attctaatac tcaatgaaaa tcaaagagca aactaggaag
    31681 ctagccgcag gttgctcaaa acagtgtttt gaggttgtgg atagaactaa cgaagtcagt
    31741 aaccatacct acggcaaggc gacgttgacg tggtttgaag agattttcta agagtataac
    31801 acgaatcttg agtacaagca accaatttgc tcacaagaaa aagcctagat aactagactt
    31861 ttttagctta ttctaccgtt actgacttgg caaggttacg tggtttgtcc acatcgaggc
    31921 cacggtggag ggttgcaaag taagcgacta attgcgtcgg tacgaccatt gaaattggtg
    31981 agaggtatgg atgtacggtc gtaaggacga tatcgtcggt atctttggct acattctctt
    32041 ctgcgatagt gaggactttg gcaccacggg ctgcgacctc ttggatattt ccacgagtat
    32101 ggttggcaag aactggatct gacaagagag ccaaaacagg cgttccttct tcaatcaagg
    32161 caatggttcc gtgcttgagt tctcctgccg caaaaccttc acactggata taagaaatct
    32221 ctttgagttt gagacttgct tccatggcta cgtagtaatc ttgaccacgt ccgatgtaaa
    32281 aggcgttacg agttgtttca agaagttcac gaaccttggc ttcaatggtt tctttctctg
    32341 aaagagttga ttcgatagac tgagctacga ttgacaattc atgaaccagg tcaaaggctt
    32401 gcgctttagc attaccattt gcttctccga ctgcttttgc aaggaaggca agggctgcga
    32461 tttgcgctgt ataggcttta gttgatgcca cggcaatttc aggacctgcg tgaaggagca
    32521 tggtatagtt ggcttcacgt gagagggttg aacctggaac gtttgtcact gttaagcttg
    32581 gaattcccat ttcattagcc ttgaccaaaa cttgacgact atccgctgtt tcaccagatt
    32641 ggctgataaa gatgaagagt ggtttcttgc tgagaagtgg cataccgtag ccccactcag
    32701 atgagattcc aagttcaact ggtgtatctg tcaattcttc caacattttc ttagaagcaa
    32761 atcctgcatg gtaagatgtt ccagctgcaa ggatgtagat gcggtctgcg tcttgaacag
    32821 ccttaatgat atctgggtct acgacaactt gaccagcctc atctgtgtag gcttggatga
    32881 gtttccgcat aacagttggt tgctcgtcaa tttccttgag catatagtaa gggtaagttc
    32941 ccttaccgat atctgacaag tcaagttcag cagtgtagct agcacgctca cgacgatttc
    33001 catcatagtc ttgaacttcc acactatcag ccttgacgat taccaactct tggtcatgga
    33061 tttccatgta ttggttagtt tcacgaatca tagccatggc gtctgagcag accatgttat
    33121 agccttctcc aagaccaatc aaaagtggtg atttattttt agctacgtag atgacttcag
    33181 gatcttgtga gtcaaccaag gcaaaggcat aagaaccacg gatgatgtga agggcttttt
    33241 tgaaggcttc aagaactgag agcccttctt cttccgcaaa ttttccaatc aaatgaacgg
    33301 ctatttcagt atctgtctgc cccttgaagt ggtgacctgc aaggtattct tccttgattt
    33361 caaagtagtt ctcaatcacc ccattatgca ccaagacaaa acgttctgtc tcagagcggt
    33421 gtgggtgagc attgtcctca gttggttttc cgtgagtagc ccaacgagta tgtccgatac
    33481 cagttgttcc ctcaacacca gctgtcttgg cagacaattc tgcaatacga ccaacagcct
    33541 tcaccaaatg gttatcagca ccatctagga caaaaattcc cgcagaatca tagccacggt
    33601 attcaagctt ttcaagccct tgaatcaaaa tatcagttgc atttgtgttt ccaacaacac
    33661 caacaattcc acacatagta tatacgacac aggcaagctg tgctttctcc ttaaaattgg
    33721 tatagtctaa ttcatctttt atagaatcag caaaaacagt atatacttgt ttctttcact
    33781 tgtcaagagt aaaaattggt atagttcaaa ttaagctcct gtaagcataa aaactctgac
    33841 cgattgggat aatcagtcag agtccttttt aaaatccatt attatcgctt aattctttga
    33901 accagtggcc tgatttcttc agacgacgtt cttgcgtttc caagtctaat tcgaccaaac
    33961 catagcgatt tttatagctg ttgagccatg accagcagtc aataaaggtc caaatcaagt
    34021 agcccttaca gttggcacca tcttcaatgg cacggtgaag ttcacgaaga tgacctttta
    34081 caaagtcaat acggtaatca tcttgaatca ttccatcttg acggaatttt tcttcccctt
    34141 caacacccat accattctca gtcaacatcc actcaatatt gccataattt tccttgatat
    34201 tttgggcgat gtcataaatc ccttgctcat aaatctccca accacggtga gaattgattt
    34261 tacgtccagg catcacataa ggctcgtaaa aatgttctgg taagagtgga ctatctggat
    34321 gcttagcaaa tcgaggagcc ataacacgca aaggttgata gtagttcaca ccaaggaagt
    34381 ccaccgtatt atcacgaatg agttccaact cttcctctgt agcatcaggt aaaagaccgt
    34441 gttcatgcaa gatttctacc aactcctgtg gataagtccc caagacagat ggatctaaga
    34501 aagattgggc ctgaaaaagg gccgcaatac gagctgcctt gacatcagca ggatgctggc
    34561 tacgtggata agccggtgtc aagttgagga caatcccaat cttggaatca ggcaaaagtt
    34621 catggcaagc cttaacagcc cggctgctgg ccaattgtgt atgataggct accttaacag
    34681 ctgcctctgc atccacctta tgtggataat gggcatcata aaaataacca aattctacag
    34741 gaacgatggg ctcgttaaag gtaatccatt gatccactaa atctccataa gtctcaaaac
    34801 aaaaacgagc atagtcttca taggctgaga ctgtcgcctt attttcccaa ccatcaccat
    34861 cctcttgaag ggcaaaaggt aaatcaaaat gatagagatt gactaacaga cgaattcctt
    34921 tagccttaat agcctcaaag accttacgat aaaaatccac accttgaggg ttgactttcc
    34981 cacagccttg tggaaaaatc cgtgaccact gaatagaagt ccgaaagact gtgtgaccag
    35041 tctctaacaa aagctcaata tcccgctccc aattttcata aaaagtcgat gtcttatctg
    35101 aaccaatccc attatagtaa cgatttggct ccacttggaa ccagtaatcc cagagattgt
    35161 ctcccttacc gtcaccagct acacgtcctt ctgtctgcgg tccagaagta gaggatcccc
    35221 agacaaaatc ctttggaaat cttagcataa catttacctc tttatctact catttctccc
    35281 attatacaga aaaaacaagg taaaaactag ttacattttt tccttgtttt tcttctgatt
    35341 atagttttta tttcttgctt aggatttcaa gcgtttcaag cacgttatct gcatgaacct
    35401 caatggtgtc accagttgcc ttgatcttaa cttctacaat gccatcggcc gcttttttac
    35461 caacagtgat acggattgga agaccaatca agtcactatc gctaaattta acaccgacac
    35521 gttcgttacg gtcatctgtc aagacttcat aaccagctcc catcaagctt gcttcaagtt
    35581 tttctgtcaa ggcttgcgct tcttcatcct tgacattaac agtaatcaaa tgcacatcaa
    35641 atggtgccaa ttctttaggg aaattgattc cccaagcgta acggtattca ccttttggcg
    35701 ttttgttaac aaagaggcga gcgtgttgct ccatcactgc tgaaagaaga cggctgacac
    35761 cgataccgta acatcccatg atgattggca cagcacgacc attttcatcc aagacatctg
    35821 ctcccatgct tgctgaatag cgagttccga gtttgaaaat atgaccgatc tcaataccac
    35881 gcgcaaagtt aaggacacct tgtccatctg gggaaatttc accctcacga acttcacgga
    35941 tatccacata ttctgcagta aaatcacggc ctgggttcac accagtcaag tggtagccat
    36001 cttcgttagc accgacaact gcattgcgaa catcttgcac cttacgatct gcaataattt
    36061 taatattctc tggcaaacca actggtccaa gtgaaccaaa tcctgcttga acaacattcg
    36121 ccacttcttc ttcgctagca acgtcaaaga aatctgctcc caagtgattt ttcaacttga
    36181 cttcgttgag ttggtcattt ccaactagaa gggctgcaac aagctcacca tctgcaatgt
    36241 agaagagggt tttaatcgtt tgttcttctg gaacattgag gaaagctgca acttcatcaa
    36301 ttgatttaac atctggcgtt gcaacacgag taacttcttc ttcagcgaca acacggttgc
    36361 ttggtttgta ctcgtttgtt gccatttcta agttagctgc atagctagac tcacttgagt
    36421 aagcaatggt atcttcacca gagactatcc atttgagcaa ttctgccttg atttcttctt
    36481 gcacttctgc aggaatttcg tcaaatgagg caactgactt gtccaagaca acccagcggt
    36541 caaggtctgt acgagcagat gtaatggcca taaattcttg gctatcctta ccacccatgg
    36601 ctccaccgtc accaataata gccttgaagt ctaaaccact acgagtgaaa atacgctcat
    36661 aagctgcttt gtactcatca taaacactat ccaaactatc atagttagcg tggaaactat
    36721 aagcatcctt catgataaac tcacgtgtac gaagaagtcc attacgcggg cgtttttcat
    36781 cacgatactt gggctgaatt tgataaaggt tgagtggcaa ttgcttgtaa gatttaacag
    36841 aatcacggac aatagctgta aaggtttctt cgtgagttgg acctaagata aagtctgatt
    36901 tttcacggtt ttttagtttg taaaggtctt caccataggt ttcgtaacga cctgattcac
    36961 gccacaattc tgcactaaga agggctggag ccaacatctc aacagcacca atcttttcga
    37021 attcttggcg catgatgttt ttagcttttt caatcacacg gttggcaagt ggtagataag
    37081 aataaacacc tgctgaaact tggcgaacat aaccagcacg caacataaga gcatggctga
    37141 taacttgagc atcgcttggc atttcgcgaa gcgttgggat aggcatttta ctttgtttca
    37201 taatattcct cgattatcta aaaaagagtc gcataatgtc attccaagtc acagcaatca
    37261 tcaagacaac catgatgacc actccggcca aggtgacata ggtttcaatt tcttgtttca
    37321 atggtttgcg gcggatggct tctaggatat tgagcacaat cttaccacca tccaaggctg
    37381 gaatcggaat aagattaaaa atcccaatat tgatggaaat cattgccaag aagtacaaga
    37441 tattttcaat tccattttta gcagcatcac tacttgcctt aaagatagca acaggtccac
    37501 ccaacttgtt caaatctggt tggaaaatca gatttttcag agctgagaga attcggagag
    37561 ctgagtcagc agcagttgta aaaccaccta caaacatgga tagaaaatct gacttacccc
    37621 ccggttgaac acctagaagg taacgacctt gactatcttt gggtgtaaca gtgacttgtt
    37681 tgtcactccc cttttcagaa atagtcacat ccaaagtcgg tgccgtctta tctttggttt
    37741 ctgtttccac agcttggatc aagctttccc agttgctaac ctcatgtgag ccaatcttgg
    37801 taatttgtgc cgtttctggt actcctacct tggccaaggc accttggggc atgatatgga
    37861 actgattggt atcaacatct ctgacaccac cctgcataaa gattaaaacc caaaaaacaa
    37921 cgacacctaa gataaaattg ttcataggac ctgcaaaatt ggtaatcagt ttgccccaga
    37981 tagtcgcatt ttgatattga acatctaaag gtgcaatccg aacctcagta ccatctgctt
    38041 ccacaaccgt tgcatcgtga tccactgcaa atgttttttc ttcttccaga accaatcctt
    38101 tgataaagag cttgtcttca aaatcaaact gggtcacctg catagggagg actgtttgat
    38161 ccaatttttt acctgagaga ttgatgcgtt taaccttacc atcatcagca agtgtcaaac
    38221 taacaggcgt tcctgtcttg atttcagttg tatcatcacc ccaaccggcc atgcggacat
    38281 agccacccag aggcaagatt cgaatggtat aggccgttcc atccttgcca atgtgagcaa
    38341 aaattttagg tcccataccg atggcaaatt cacgtactaa aatccctgat ttcttggcaa
    38401 agtagaagtg cccgaactcg tgcaccacta caataatccc aaaaactaga ataaaggtta
    38461 aaattccaag catagtgttt cctccgtctt ttgattaaaa gagtccaaat aagtgcatga
    38521 ttggaaatac aagcaacata ctatcgaaac gatccaaaac accaccatgt ccagggataa
    38581 atttcccaga atccttaaca ccaaaatgac gtttgatcga actttctagt aaatcaccaa
    38641 attgtccagc aatgctaaag aaaatagcaa agactgacat cttgtaaatt ccatatggaa
    38701 gagcaactgt actgtcaact atcataaaga taatggttac taaaattgct cctaaaatac
    38761 cacccaaggc accctcaagg gttttattag gcgataccct tggtgctaac tttcgtttcc
    38821 catagttcat cccaacaaga taggcaccac tgtctgtcgc ccagacgata cacaaggcta
    38881 agagagcctt gtccaaacct gcaacacgag catctagtaa agcattaaat ccaaagccca
    38941 cgtagaagct catagcaaga gggaaaaccg catcctcaat cgtataagac ttgctaaaaa
    39001 cggtcgttcc taacatgatt gaaatcaaaa cactataggc aaccacattc ccatcaactg
    39061 gcaaaaaagt caggtaattc tccaagggaa tggtcaatgc aaaggttgca aagagggtca
    39121 agaggccctc catcgtcatg gtctctagac ctctcatctt caaaagttca tgcatggcta
    39181 gcatggctat gattccgatt gctatctgaa gcaagaggcc cccaatcatt aaaattggta
    39241 ggaaaatagc cagggcaatc cctgcaaaca aggttctttt ctgtaaatcc tgggtcatat
    39301 ttcctcctaa actcctccaa atcggcgatg acgacgatta taggcaagaa tagcttcctg
    39361 caaggccgct tcgtcaaaat caggccataa ggtgtccgta aaataaagct cactataggc
    39421 tccctgccat ggaaggaaat tgctcaaacg taattctcca ctagtacgga taatcaagtc
    39481 tgggtctcgt aagtccttag gcaaatgctg agtaaagaga tagttaccaa tcaattcctc
    39541 tgtgatgtca cctgggttga ttttggcatc taaaacatcc tgggaaatca acttaagcgc
    39601 ctgtgtaatc tcagcacgtc caccatagtt aagagcaaaa ttaagaatca atcctgtgtt
    39661 gttcttagtc aattcctcag ccttggttaa agcttcaaag gtttgcttag gcaggcggtc
    39721 tgtctcccca atcatttgaa tcttaacatt attcgcatgt agttccggga cataattatc
    39781 ataaaactct actggcaagt tcatgataaa cttgacttcc tgatctggac gggtccagtt
    39841 ttccgtagaa aaagcataga ccgtaataac cttgacgccc agtttgttgg ctgccttggt
    39901 cacggtttgc aatgcttcca tgcccgcctt atgtccaaaa actcgcggtt gcatacgttt
    39961 tttagcccaa cggccattgc catccatgat gatgccgata tgagcaggaa cctgtgtcgg
    40021 aacctctact tccacagcct tatctttctt aaaaaatcca aacatgatct tattcctatt
    40081 caaaaatcta tcgtttcatt ataccatatt tccccatttt cttctatcac taagctattt
    40141 attctcaggc accatgccca tttttcaaaa aaataagccg cctgattggg cgactttatt
    40201 tttataggga gattattatg aaaaagtttt aggagtttaa gttaaggtct tcttaactta
    40261 tgaacttagt gtacactccc tagcttaaag tttccttaag tatttttaaa aatcaaattt
    40321 ttccatttct cctgccaatt tttcttggat aaacgtgttt gatagagttc cattcggtct
    40381 tcattttcta agaaatgagg agttggacga acttgaaaat tcaaaatatc ctccaaacca
    40441 taaggtgcat agagttcaaa atctgattct tcattcaagc gcagtccaac tgccgtacac
    40501 cgttctggat acttactcat agcatcacga gaactggtat aggaagcagt gtgaggactg
    40561 tgctggtgca tatagacctg atttttcaat tcccactggt actgaggaaa atcctctctc
    40621 agctttttct ccagtaataa ggtttcctca taagaaaaat ctggatcaaa gaaaatcaca
    40681 tctatatctg tttcatgatc aaaaggggat ttgtctgaca aaagattcca gatgaaattt
    40741 ctgacagaac ctgctgccaa ctacgagtct ttcaaaccaa ggtctcggat gatcgtcaga
    40801 atggccatca tatctggatt ttctctaaaa gcctctaaga tttcttgctt atttttcact
    40861 gtattcataa cctaagtgct catatgcctt agcagtcgcc acccgtccag accgtgtccg
    40921 catgataaaa cctttttgaa tcaagtaagg ctcatacatg tcttcaactg tctcacgctc
    40981 ttcggcgata ttgacagaaa gagttcctag accaacaggt cctccactgt acatctcaat
    41041 catggtacga aggatttttt gatccacata gtccaaacct tcatggtcaa catccagcat
    41101 agtcaaagcc ttatcggtaa taatatcatc gattacccca ttccccatta tctgggcaaa
    41161 atcgcgcacg cgcttgagga gacgattggc aatacgaggg gttccacgac tacgtagggc
    41221 caactcagat gctgcctcat gagtgatttc catctcaaaa atatctgccg tccgctcgac
    41281 aatttctgtc aagtcagcat gggcataata ctccatatga cctgtaatcc caaaacgtgc
    41341 ccgtagtgga tttgagagca taccagcccg agtcgtcgca ccaatcaagg taaaaggagg
    41401 caactccaaa tgaacactgc gactgccttc accagcccca atcataatat cgatgtagaa
    41461 gtcctccatg gcactataaa gcacttcttc cactgacatg ggtaagcgat gaatctcgtc
    41521 aataaagagg acatctccag gctctaactc attcaaaatc gctaccaaat cacccgcttt
    41581 ttcgataaca ggaccagacg tttgcttgag attgactccc agttcattgg caatgacaaa
    41641 agccatggtt gttttcccaa gccctggagg gccaaataag agcacatgat ccagcgcttc
    41701 atcccgcatt ttagcggctt cgataaagat ctgaagctga tccttaacct tatcctgacc
    41761 aatatattca cgtaaatact gaggacggag cgtgcgttct actaactcct catcacccat
    41821 catctcatta tctaaaattc tactcatggc tctattatat caaaaaaaca agccacaaac
    41881 aaaaaagcca cctgattggg tgactcctaa gtttagcact tatgtggtat aatattatac
    41941 ggcacttcta caccgcctac gaaaggaggt gagatagccc atgatggaat tagtactcaa
    42001 aactatcatc ggaccaattg tggtcggtgt cgttcttcgt atagtcgata aatggctaaa
    42061 caaggacaaa tagtgtcaaa aaagacctca agcttatttg gtcgtgagct tggggtcttt
    42121 tctagcctat gatatagaac tagtactcaa ttccttttta ttatcccata gttcacgaat
    42181 tttgtcaaag gtttacattt tcttcaaccg ctgtacgaca agacggttaa gattaagaga
    42241 acgttaggga ttctatcaat ttcatagaaa ttttgatttc gtaaacgaag agacaatctt
    42301 acatgtcact tctcatttaa tacgccacta ctagacaagc aaaatcatta ttacagtagt
    42361 tccagttctt caattaacag tcacttacaa tcaaattgag tttgaactag ctgaagcgac
    42421 cacagaccta tttcttagtt atattcgcta aaaaagtccc cgccaattcc ccgaccaaaa
    42481 tccgaaaaat accgaaaaat atcgaaaaat tatttttaga atagtcccca aaagcctgaa
    42541 atagagctaa aaaactccac ctgattgggt ggagttaagg gagattatta tgaaaaagaa
    42601 aagtttagga ttttattaaa taaagttagg aggtctttat ttaataacta catgatacaa
    42661 gacgaaactt aaaactagct taacttttct aaaattttac tattttgcaa aaaatttcta
    42721 tcaccagcac ctcaccacgc aaaaaagcca cctgattggg
//
LOCUS       DAVLZG010000008        40374 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLZG010000008 DAVLZG010000000
VERSION     DAVLZG010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.008"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            148..6834
                     /locus_tag="VYO72_000437"
     CDS             148..6834
                     /locus_tag="VYO72_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1706877.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGKERIFT
                     VINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEADQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7082..7936)
                     /locus_tag="VYO72_000438"
                     /pseudo
     CDS             complement(7082..7936)
                     /locus_tag="VYO72_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8148..8507)
                     /locus_tag="VYO72_000439"
     CDS             complement(8148..8507)
                     /locus_tag="VYO72_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1706878.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKLSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8599..9555
                     /locus_tag="VYO72_000440"
                     /pseudo
     CDS             8599..9555
                     /locus_tag="VYO72_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9539..10087
                     /locus_tag="VYO72_000441"
     CDS             9539..10087
                     /locus_tag="VYO72_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1706879.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKQVYAFD
                     IQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSVITR
                     PQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAIYRT
                     LNQVNNPPFLVMIEKLERYRHG"
     gene            10080..10334
                     /locus_tag="VYO72_000442"
     CDS             10080..10334
                     /locus_tag="VYO72_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706880.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10346..12400
                     /locus_tag="VYO72_000443"
     CDS             10346..12400
                     /locus_tag="VYO72_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1706881.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLILPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12579..13439
                     /locus_tag="VYO72_000444"
     CDS             12579..13439
                     /locus_tag="VYO72_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1706882.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDQVFKKD"
     gene            13650..14360
                     /gene="ccdA2"
                     /locus_tag="VYO72_000445"
     CDS             13650..14360
                     /gene="ccdA2"
                     /locus_tag="VYO72_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1706883.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            14380..14946
                     /locus_tag="VYO72_000446"
     CDS             14380..14946
                     /locus_tag="VYO72_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1706884.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14957..16069
                     /gene="msrB"
                     /locus_tag="VYO72_000447"
     CDS             14957..16069
                     /gene="msrB"
                     /locus_tag="VYO72_000447"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1706885.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            16337..17074
                     /locus_tag="VYO72_000448"
     CDS             16337..17074
                     /locus_tag="VYO72_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1706886.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            17071..18762
                     /locus_tag="VYO72_000449"
     CDS             17071..18762
                     /locus_tag="VYO72_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1706887.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            18878..19441
                     /locus_tag="VYO72_000450"
     CDS             18878..19441
                     /locus_tag="VYO72_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1706888.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            19463..24922
                     /locus_tag="VYO72_000451"
     CDS             19463..24922
                     /locus_tag="VYO72_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1706889.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEQAPTAPVEPEKQPEVPEEEKAVEETPKPEDKIKGIGTKEPVDK
                     SELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASEPVKQPEVNSETNKLKTAI
                     DALNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTEVTKAEKVAANTDAKQSEVNEAV
                     EKLTATIEKLVELSEKPILTLTSTDKKILEREAVAKYTLENQNKTKIKSITAELKKGE
                     EVINTVVLTDDKVTTETISAAFKNLEYYKEYTLSTTMIYDRGNGEETETLENQNIQLD
                     LKKVELKNIKRTDLIKYENGKETNESLITTIPDDKSNYYLKITSNNQKTTLLAVKNIE
                     ETTVNGTHVYKVTAIADNLVSRTADNKFEEEYVHYIEKPKVHEDNVYYNFKELVEAIQ
                     NDPSKEYRLGQSMSARNVVPNGKSYITKEFTGKLLSSEGKQFAITELEHPLFDKIKAG
                     TVKNINFENIDINVSNQDNIATIANEINGTTRIENIKATGTITARNNVAGFVNNIKEN
                     AALENVAFIGNINSVGNNSTVGGIAGSNYMGFVNKAYVDANITAANASASMLVPLVTY
                     MLNSYQYGTKSKVTNSVAKGTLDVKNTRFVGGVVAKTWPWGVIKDIVTYAKVIKGEEV
                     YGSNEINDGDARQFLSDIYRVNGASSGANNFTNLQKIKQLTKEQADAKVATFNITADK
                     LESELSPLAKLNEEKAYSSIQDYNAEYNQAYKNLEKLIPFYNKDYIVYQGNKLNKEHP
                     LNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDYFNLSSSSEGLSNVKEYTITD
                     LGIKYTPNIVQKDNTTLVNDIKSILEPVDLQSQTMYQHLNRLGDYRVNAIKDLYLEES
                     FTAVKKNLTNLITKLVQNEEHQLNDSPAARQMLRDKVEKNKAALLLGLTYLNRYYGVK
                     FGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIKGSRTFDAFGEVLAKYTKSGN
                     LDVFLNYNRQLFTNIDNMNDWFIDATKDHVYIAERASEVEEIKNAKYRAYANLNVAQH
                     RKMILPLLNITKSHMFIASNYNAIAIGSAEKLGKKSLEDIKASVDYAADGYRNYYDFW
                     YRLVPDNVKQYLLRDTVIPIWEGYNAPGGWVEKYGRYNTDNVYTPLREFFGPIEKYYG
                     YNGTGAYAALYDNPMDPRSDVSYVALNMIGDYGISVYTHETTHINDRKIYLGGFGRRE
                     GTDAEAFAQGMLQLPVPGSGFNEYGSLGLNTVFKKPNDGNQWYDTDPKSLTTRDDIDK
                     YMRGYNDALMLVDHLEADAVINQNNKELNGAWFKKIDKKFRDASQLNQWDEIRNLTTE
                     EKDNLNITSIDSLIDQQLMTNRQIGNRVYKPEVVSQYDQSPYVGVEMTAGIYGGNTSK
                     GAPGAVSFKHNAFRLWGYYGYLNGFLGYTSNKYKQQSTKDGESVLSDEYIIKKISNNT
                     FNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDDLLTLFKEAVKKDAETLKQEA
                     NGHKTVSMTNTVKLKEAVYKKLLQQTDSFKTSIFR"
     gene            24983..26704
                     /gene="pabB"
                     /locus_tag="VYO72_000452"
     CDS             24983..26704
                     /gene="pabB"
                     /locus_tag="VYO72_000452"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1706890.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            26705..27322
                     /locus_tag="VYO72_000453"
     CDS             26705..27322
                     /locus_tag="VYO72_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1706891.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            27372..28370
                     /locus_tag="VYO72_000454"
     CDS             27372..28370
                     /locus_tag="VYO72_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1706892.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            28497..29456
                     /locus_tag="VYO72_000455"
     CDS             28497..29456
                     /locus_tag="VYO72_000455"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1706893.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTVGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            29553..30392
                     /locus_tag="VYO72_000456"
     CDS             29553..30392
                     /locus_tag="VYO72_000456"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1706894.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(30440..30610)
                     /locus_tag="VYO72_000457"
     CDS             complement(30440..30610)
                     /locus_tag="VYO72_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1706895.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            30731..31615
                     /gene="miaA"
                     /locus_tag="VYO72_000458"
     CDS             30731..31615
                     /gene="miaA"
                     /locus_tag="VYO72_000458"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1706896.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHFVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            31608..32846
                     /gene="hflX"
                     /locus_tag="VYO72_000459"
     CDS             31608..32846
                     /gene="hflX"
                     /locus_tag="VYO72_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1706897.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            32839..33462
                     /locus_tag="VYO72_000460"
     CDS             32839..33462
                     /locus_tag="VYO72_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1706898.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLVQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            33477..34406
                     /locus_tag="VYO72_000461"
     CDS             33477..34406
                     /locus_tag="VYO72_000461"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1706899.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            34427..35182
                     /locus_tag="VYO72_000462"
     CDS             34427..35182
                     /locus_tag="VYO72_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1706900.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(35236..36144)
                     /locus_tag="VYO72_000463"
     CDS             complement(35236..36144)
                     /locus_tag="VYO72_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1706901.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            36208..36477
                     /locus_tag="VYO72_000464"
     CDS             36208..36477
                     /locus_tag="VYO72_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1706902.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            36477..36857
                     /locus_tag="VYO72_000465"
     CDS             36477..36857
                     /locus_tag="VYO72_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1706903.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            36946..37173
                     /locus_tag="VYO72_000466"
     CDS             36946..37173
                     /locus_tag="VYO72_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706904.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLEYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(37213..37938)
                     /locus_tag="VYO72_000467"
     CDS             complement(37213..37938)
                     /locus_tag="VYO72_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV1706905.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            38100..39941
                     /gene="typA"
                     /locus_tag="VYO72_000468"
     CDS             38100..39941
                     /gene="typA"
                     /locus_tag="VYO72_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1706906.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            39961..40215
                     /locus_tag="VYO72_000469"
     CDS             39961..40215
                     /locus_tag="VYO72_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1706907.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        12489 a         7496 c         8886 g        11503 t
ORIGIN      
        1 aatcatatct acggcaaggc gacactgacg aagtttgaat tggattttcg cagagtgtaa
       61 attgttgaaa ctaggttgtc ataccatgta taccacttgg gctttggtag tagctaactg
      121 cactaaatat aatataagga gggttttatg gggaaaggcc attggaatcg gaaaagagtt
      181 tatagcattc gtaagtttgc tgtgggagct tgctcagtaa tgattgggac ttgtgcagtt
      241 ctattaggag gaaatatagc tggagaatct gtagtttatg cggatgaaac acttattact
      301 catactgctg agaaacctaa agaggaaaaa atgatagtag aagaaaaggc tgataaagct
      361 ttggaaacta aaaatgtagt tgaaaggaca gaacaaagtg aacctagttc aactgaggct
      421 attgcatctg agaagaaaga agatgaagcc gtaactccaa aagaggaaaa agtgtctgct
      481 aaaccggaag aaaaagctcc aaggatagaa tcacaagctt caagtcaaga aaaaccgctc
      541 aaggaagatg ctaaagctgt aacaaatgaa gaagtgaatc aaatgattga agacaggaaa
      601 gtggatttta atcaaaattg gtactttaaa ctcaatgcaa attctaagga agccattaaa
      661 cctgatgcag acgtatctac gtggaaaaaa ttagatttac cgtatgactg gagtatcttt
      721 aacgatttcg atcatgaatc tcctgcacaa aatgaaggtg gacagctcaa cggtggggaa
      781 gcttggtatc gcaagacttt caaactagat gaaaaagacc tcaagaaaaa tgttcgcctt
      841 acttttgatg gcgtctacat ggattctcaa gtttatgtca atggtcagtt agtggggcat
      901 tatccaaatg gttataacca gttctcatac gatatcacca aataccttca taaagatggt
      961 cgtgagaatg tgattgctgt ccatgcagtc aacaaacagc caagtagccg ttggtattca
     1021 ggaagtggta tctatcgtga tgtgacttta caagtgacag ataaggtgca tgttgagaaa
     1081 aatgggacaa ctattttaac accaaaactt gaagaacaac aacatggcaa ggttgaaact
     1141 catgtgacca gcaaaatcgt caatacggac gacaaagacc atgaacttgt agccgaatat
     1201 caaatcgttg aacgaggtgg tcatgctgta acaggcttag ttcgtacagc gagtcgtacc
     1261 ttaaaagcac atgaatcaac aagcctagat gcgattttag aagttgaaag accaaaactc
     1321 tggaccgttt taaatgacaa acctgccttg tacgaattga ttacgcgtgt ttaccgtgac
     1381 ggtcaattgg ttgatgctaa gaaggatttg tttggttacc gttactatca ctggactcca
     1441 aatgaaggtt tctctttgaa tggtgaacgt attaaattcc atggagtatc cttgcaccac
     1501 gaccatgggg cgcttggagc agaagaaaac tataaagcag aatatcgccg tctcaaacaa
     1561 atgaaggaga tgggagttaa ctccatccgt acaacccaca accctgctag tgagcaaacc
     1621 ttgcaaatcg cagcagaact aggtttactc gttcaggaag aggcctttga tacttggtat
     1681 ggtggcaaga aaccttatga ctatggacgt ttctttgaaa aagatgccac tcacccagaa
     1741 gctcgaaaag gtgaaaaatg gtctgatttt gacctacgta ccatggtcga aagaggcaaa
     1801 aataaccctg ctatcttcat gtggtcaatt ggtaatgaaa taggtgaagc taatggtgat
     1861 gcccactctt tagcaactgt taaacgtttg gtcaaggtta tcaaggatgt tgataagact
     1921 cgctatgtta ccatgggagc agataaattc cgtttcggta atggtagcgg agggcatgag
     1981 aaaattgctg atgaactcga tgctgttgga tttaactatt ctgaagataa ttacaaagcc
     2041 cttagagcta agcatccaaa atggttgatt tatggatcag aaacatcttc agctacccgt
     2101 acacgtggaa gttactatcg ccctgaacgt gaattgaaac atagcaatgg acctgagcgt
     2161 aattatgaac agtctgacta tgggaatgat cgtgttggtt gggggaaaac agcaaccgct
     2221 tcatggactt ttgaccgtga caacgctggc tatgctggac agtttatctg gacaggtacg
     2281 gactatattg gtgaacctac accatggcac aaccaaaatc aaactcctgt taagagctct
     2341 tactttggta tcgtagatac agccggcatt ccaaaacatg acttctacct ctaccaaagc
     2401 caatgggttt ctgttaagaa gaaaccgatg gtacaccttc ttcctcactg gaactgggaa
     2461 aacaaagaat tagcatccaa agtagctgac tcagaaggta agattccagt tcgtgcttat
     2521 tcgaatgctt ctagtgtaga attgttcttg aatggaaaat ctcttggtct taagactttc
     2581 aataaaaaac aaaccagcga tgggcggact taccaagaag gtgcaaatgc taatgaactt
     2641 tatcttgaat ggaaagttgc ctatcaacca ggtaccttgg aagcaattgc tcgtgatgaa
     2701 tctggcaagg aaattgctcg agataagatt acgactgctg gtaagccagc ggcagttcgt
     2761 cttattaagg aagaccatgc gattgcagca gatggaaaag acttgactta catctactat
     2821 gaaattgttg acagccaggg gaatgtggtt ccaactgcta ataatctggt tcgcttccaa
     2881 ttgcatggcc aaggtcaact ggtcggtgta gataacggag aacaagccag ccgtgaacgc
     2941 tataaggcgc aagcagatgg ttcttggatt cgtaaagcat ttaatggtaa aggtgttgcc
     3001 attgtcaaat caactgaaca agcagggaaa ttcacactga cagcccattc agatctcttg
     3061 aaatctagtc aagtcactgt ctttactggt aaaaaagaag gacaagagaa gactgttttg
     3121 gggacagaag tgccaaaagt acagaccatt attggagagg cacctgaaat gcctaccact
     3181 gttccgtttg tatacagtga tggtagccgt gcagaacgtc ctgtaacctg gtcttcagta
     3241 gatgtgagca agcctggtat tgtaacggtg aaaggtatgg ctgacggacg agaagtagaa
     3301 gctcgtgtag aagtgattgc tcttaaatca gagctaccag ttgtgaaacg tattgctcca
     3361 aatactgact tgaattctgt agacaaatct gtttcctatg ttttgactga tggaagtgtt
     3421 gaagagtatg aagtggacaa gtgggagatt gccgaagaag ataaagctaa gttagcaatt
     3481 ccaggttctc gtattcaagc gaccggttat ttagaaggtc aaccaattca tgcaaccctt
     3541 gtggtagaag aaggcaatcc tgcggcacct gcagtaccaa ctgtaacggt tggtggtgaa
     3601 gctgtcacag gtcttactag tcaaaaacca atgcaatacc gcactcttgc ttatggagct
     3661 aagttgccag aagtcacagc aagtgctaaa aatgcagctg ttacagttct tcaagcaagc
     3721 gcagcaaacg gcatgcgtgc gagcatcttt attcagccta aagatggtgg ccctcttcaa
     3781 acctatgcaa ttcaattcct tgaagaagcg ccaaaaattg ctcacttgag cttgcaagtg
     3841 gaaaaagctg acagtctcaa agaagaccaa actgtcaaat tgtcggttcg agctcactat
     3901 caagatggaa cgcaagctgt attaccagct gataaagtaa ccttctctac aagtggtgaa
     3961 ggggaagtcg caattcgtaa aggaatgctt gagttgcata agccaggagc agtcactctg
     4021 aacgctgaat atgagggagc taaaggccaa gttgaactca ctatccaagc caatactgag
     4081 aagaagattg cgcaatccat ccgtcctgta aatgtagtga cagatttgca tcaggaacca
     4141 agtcttccag caacagtaac agttgagtat gacaaaggtt tccctaaaac tcataaagtc
     4201 acttggcaag ctattccgaa agaaaaacta gactcctatc aaacatttga agtactaggt
     4261 aaagttgaag gaattgacct tgaagcgcgt gcaaaagtct ctgtagaagg tatcgtttca
     4321 gttgaagaag tcagtgtgac aactccaatc gcagaagcac cacaattacc agaaagtgtt
     4381 cggacatatg attcaaatgg tcacgtttca tcagctaagg ttgcatggga tgcgattcgt
     4441 ccagagcaat acgctaagga aggtgtcttt acagttaatg gtcgcttaga aggtactcaa
     4501 ttaacaacta aacttcatgt tcgcgtatct gctcaaactg agcaaggtgc aaacatttct
     4561 gaccaatgga ccggttcaga attgccactt gcctttgctt cagattcaaa tccaagcgac
     4621 ccagtttcaa atgttaatga caagctcatt tcctacaata accaaccagc caatcgttgg
     4681 acaaactgga atcgtagtaa tccagaagct tcagtcggtg ttctgtttgg agattcaggt
     4741 atcttgagca aacgctccgt tgataatcta agtgtcggat tccacgaaga ccatggagtt
     4801 ggtgcaccga agtcttatgt gattgagtat tatgttggta agactgtccc aacagctcct
     4861 aaaaacccta gttttgttgg taatgaggac catgtcttta atgattctgc caactggaaa
     4921 ccagttacta atctaaaagc ccctgctcaa ctcaaggctg gagaaatgaa ccactttagc
     4981 tttgataaag ttgaaaccta tgctattcgt attcgcatgg ttaaagcaga taacaagcgt
     5041 ggaacgtcta tcacagaggt acaaatcttt gcgaaacaag ttgcggcagc caaacaagga
     5101 caaacaagaa tccaagttga cggcaaagac ttagcaaact tcaaccctga tttgacagac
     5161 tactaccttg agtctgtaga tggaaaagtt ccggcagtca cagcaaatgt tagcaacaat
     5221 ggtctcgcta ccgtcgttcc aagcgttcgt gaaggtgagc cagttcgtgt catcgcgaaa
     5281 gctgaaaatg gcgacatctt aggagaatac cgtctgcact tcactaagga taagaactta
     5341 ctttctcata aaccagttgc tgcggttaaa caagctcgct tgctacaagt aggtcaagca
     5401 cttgaattgc cgactaaggt tccagtttac ttcacaggta aagacggcta cgaaacaaaa
     5461 gacctgacag ttgaatggga agaagttcca gcggaaaatc tgacaaaagc aggtcaattt
     5521 actgttcgag gccgtgtcct tggtagtaac cttgttgctg aggtcactgt acgagtgaca
     5581 gacaaacttg gtgagactct ttcagataac cctaactatg atgaaaacag taaccaggcc
     5641 tttgcttcag caaccaatga tattgacaaa aactctcatg accgcgttga ctatctcaat
     5701 gacggagatc attcagaaaa tcgtcgttgg acaaactggt caccaacacc atcttctaat
     5761 ccagaagtat cagcgggtgt gatcttccgt gaaaatggta agattgtaga acggactgtt
     5821 gctcaagcca aacttcactt ctttgcagat agtggtacgg atgcaccatc taaactcgtt
     5881 ttagaacgct atgtcggccc aggctttgaa gtacctacct actattcaaa ctaccaagcc
     5941 tacgaatctg gacatccatt taacaatcca gaaaattggg aagctgtgcc ttatcgtgcg
     6001 gataaagaca tcgcagctgg tgatgaaatc aacgtaacat ttaaagctgt caaagccaaa
     6061 gccatgagat ggcgtatgga gcgtaaagct gacaagagcg gtgttgcgat gattgagatg
     6121 accttccttg caccaagtga attgcctcaa gaaagcacgc aatcaaagat tcttgtagat
     6181 ggaaaagaac ttgctgattt cgctgaaaat cgtcaagact atcaaattac ctataaaggt
     6241 caacggccaa aagtctcagt tgaagaaaac aatcaagtag cttcaactgt ggtagatagt
     6301 ggagaagata gccttccagt acttgttcgc ctcgtttcag aaagtggaaa acaagtcaag
     6361 gaataccgta tccagttgac taaggaaaaa ccagtttctg ctgtacaaga agatcttcca
     6421 aaactcgaat ttgttgaaaa agatttggcc tacaagacag ttgagaaaaa agattcaaca
     6481 ctgtatctag gtgaaactcg tgtagaacaa gaaggaaaag ttggaaaaga acgtatcttt
     6541 acagtgatta atcctgatgg aagtaaggaa gaaaaactcc gtgaagtggt agaagttccg
     6601 acagaccgca tcgtcttggt tggaaccaaa ccagtagctc aagaagctaa aaaaccacaa
     6661 gtgtcagaaa aagcagatac aaaaccaatt gattcaagtg aagctgatca aactaataaa
     6721 gcccagttac caaatacagg tagtgcggca agccaagcag cagtagcagc aggtttagct
     6781 cttctaggtt tgagtgcagg attagtagtt actaaaggta aaaaagaaga ctagaaattt
     6841 tgataccttc tttatcatta aagaccaaag aaaaactctt gtcctaaata gaagataaag
     6901 agtctggaac aaaatagttc tcaaccacaa aaaagctaga tatttccaat tgcggaactc
     6961 tagcttttta attttgagtc gttctcttat tgtatagtag attgaaacta gaatagtaca
     7021 cttctacttc taaaacattg ttagaaatca atttgactgt ccttatcgat ttgtcctggt
     7081 cttatttcat ttcactatgt tttaggaggt tattggccat aagtaccaat cccatgtcaa
     7141 ttctcacttg acgcttccct ctcagattac atctcttgta acccaaacaa gcctttatct
     7201 gcccaaagac aggtttcaca tcaatcttgc gttgagcgaa atctgtctac cttcaggaga
     7261 taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca tatacagtcc
     7321 cttttgaggg actgattcag gttcatcagc gtagtaaacc ttgatttcct gttgaaagtc
     7381 tgtctgtgtt ttctgatgtt tggtatggtg aaaacgataa taccagccat caggatgtgt
     7441 gtagctatcc tccttgtcat tatagtgcca attcgctaag tttttagctg actgtttatg
     7501 tcctctcttt tgtttcttat caaacatggc atatttaatc agaaggggag gatttcttct
     7561 tgaaaataga cctgtatctg ttcttgaagt ttggcggaga atttctctgt cgttttcttc
     7621 cacacaaaac tatacttgtt ggcattggct tcaatcttag ttccgtcaat aaacaaacaa
     7681 tctaaggtca ctaactcttc catttttcaa tttttcgacc agagaaaatc ccttgtgaat
     7741 aggcaaatag aagagtagat acaagcattt taaggtgata agacgggcga tcaaaggcat
     7801 gatagaaggc gtagaagtga tgttcctcca aggtattcac cactttttca atagtaaaga
     7861 cgagatggtc ttgtggtaag aaggaactga tttctagtgg taaagttgtt tgatttgtgt
     7921 tatagtgaat atgcatggga tagcctttct aaatggttta ttgggcaatt ctattttacc
     7981 aagactatcg taaccatgca aaaaaagcaa cggcaaatcc gttgcttttt ttggagataa
     8041 gagactattg tcccagactc ttttctttgt ataaaattgt atagtgttat tgtctatact
     8101 attttgtaga gaaagcaaaa atccctagaa aatgcttagg gattcgacta tttcattaag
     8161 aacaattcaa caatcatttc tatatacatg ataagggtta ataagaatcc tgcacgccag
     8221 aagaatttga tgaatttagg atagtaaaag ctgagttttt tcaaaaggaa gaaaaagacg
     8281 agaataatgg ctaggattga gagggctagc cccagtctag ggaggaaatt atgggtaaag
     8341 gttttagctg taatcaggta atattcaaat accaagaccg gaaaagccaa atccgcaaag
     8401 tttcgtccta gtttttttaa tctaaaaagt ttggttagga taatgcagac gactaaggtc
     8461 agtatcaata ataaaataga tgctaatttc attaaaatca tacccatatt gtatcataaa
     8521 aaaaagctaa tggaaacgag aaacagagga atttatagga aagtcaggct tttgagattg
     8581 tgggtgattt ttgttataat gaaagttata aaatcttata ataccttgaa tgattattat
     8641 cgaaaactct ttggagaaaa gacttttaaa gtccctattg atgcggaatt tgactgtccc
     8701 aatcgtgatg gaactgtggc tcatggaggc tgtacttttt gtacggtttc aggttctgga
     8761 gatactattg tagccccaga tgcgcctatc cgtgagcaat tttataagga aattgacttt
     8821 atgcaccgta agtggccgga tgttcagaag tatctggttt attttcaaaa ttttaccaac
     8881 acccatgaaa aggtggaagt tattcgagag cgttatgaac aggctatcaa tgagccaggt
     8941 gtggtaggaa tcaatattgg aatgcgccca gactgtttac cagacgaaac catcgaatat
     9001 ttggctgagt tatcggagtg catgcatgtg acggttgaat tgggcttgta gactacttat
     9061 gaagcaactt ctgacctgat taaccgtgcg tattcttatg aattgtaggt ggaaacggtc
     9121 aagcgtttga gaaagtatcc caagattgag attgtttccc atttgattaa tggtttgcct
     9181 ggtgaaaccc atgagatgat ggttgaaaat gtccgccgtt gtgtcacgaa taacgatatt
     9241 caagggatta aactgcattt gctccatctt atgacaaata ctcgtatgca acgagattac
     9301 catgagggac gtttacaatt gatgagtcag gacgaatatg tcagggtcat ctgtgaccaa
     9361 ctggaaatca ttcccaaaca tatcgtcatc catcgaatca caggagatgc acctagggat
     9421 atgctgattg ggcttatgtg gagcctcaat aaatgggaag ctctcaacag cattgagatg
     9481 gagatgcgac gtcgtggaag tgttcaagga tgcaaggctg taaaacagga gtttgaaaat
     9541 gaaaagacca cttgagatgg cacatgattt tttggctgag gtcgtgacaa aagaggatgt
     9601 cgtagtggat gcgactatgg gaaatggtca tgacacgctt tttttagcca agcaagtcta
     9661 tgcctttgat attcagaagc aagccttgga aaagacccaa gagcgtttgc atcaggctgg
     9721 cttgacaaat gcccagttaa tcttgcaagg ccatgagaca ctggaccagt ttgtgacaaa
     9781 agctaaggca gggattttta atttgggcta tttgccgtca gctgataagt ctgtcatcac
     9841 ccgaccgcag acaacgattg aggcattaga aaagctatgt ggcttacttg tcaagggtgg
     9901 acgaattgct attatgattt actatggtca tgaaggaggc gacctcgaga gagatgctgt
     9961 cttggatttt gtaatccagt tgaaccaaca agagtacaca gctgccattt accgaacttt
    10021 aaaccaagtc aacaacccgc cgtttttagt gatgattgaa aaattagaga gatacagaca
    10081 tggataaaca atacctacac gaaaagctgg atgccatgcg ccagaatttt gttgaatcaa
    10141 cccaccacga acgatcggtg ggcgtgctag accaagcgca tatgagcaaa aaaatgctta
    10201 aaatcaagaa aaaattagtt gctcttgaaa tggaacggtg ccagagaaaa attgagcaca
    10261 aagactgttc caagattgac caaaaaatca aagagcagaa ggagatattt gaatcctgtt
    10321 gtaaaaaaga ttaaggagga cgtgcgtgga attactgatt tacctcatcc tatttttact
    10381 ggttttgatt gtctcaagta caaccaataa gctcctgccc tttttgcctc tccctttggt
    10441 gcaaattctt ttgggaattg tgattggtct ctttttaccc aataccgact ttcacctcaa
    10501 tacggagttg tttttggccc tggttatcgg acccttgctt ttccgagagg ctgaagaagc
    10561 agatgttacg gctattttaa aacactggcg aatcattgtt tatctcatat ttccagtgat
    10621 ttttatctcg accctgagtt tgggtggctt ggcccatctt ctttggttca gccttccctt
    10681 ggcagcttgc ttggctgttg gggcagccct tggtcctacg gacttggtgg cctttgcctc
    10741 tctttcggag cgttttagct ttcctaagcg cgtgtccaat attcttaagg gcgaaggact
    10801 cttgaatgat gcttctggtt tggtggcttt tcaggtagct ttgacagctt ggacaactgg
    10861 agctttttct ctggggcaag ctagcagttc gctcatcttt tcaatcctag gcggtttttt
    10921 aattggattt ttaacagcca tgaccaaccg cttcctccat accttcttgc taagtgtgcg
    10981 cgcaacggat attgccagtg aacttttatt agaattaagt ttgcctctag tgaccttctt
    11041 tctggcagaa gaagttcatg tttcagggat tattgccgtc gtagttgctg gaattttaaa
    11101 ggcaagtcgt ttcaagaaaa tcacgctcct cgaagcccaa gtggatacgg tgaccgagac
    11161 ggtctggcat acagtgacct ttatgctcaa cggttctgtc tttgtgattt tagggatgga
    11221 gttggaaatg atagcagaac ctatcttgac caatccaatc tataatcctc tacttttatt
    11281 gctatctctc atcgccctta cctttgtcct ctttgtcatt cgttttatta tgatctatgg
    11341 ctattatgcc tatagaaccc gacgcctcaa gaaaaagcta aataagtata tgaaggacat
    11401 gtttctcttg accttttcag gtgttaaggg aacggtgtcg attgctacga ttctcttgat
    11461 accaagtaat ctagaacaag agtatcctct tttgcttttc cttgttgcag gtgtgacgct
    11521 tgtcagcttt ttaacaggtc tcttgatctt gcctcatctt tctgatgaag aggaagaaag
    11581 caaggattat ctcatgcata tcgccatttt gaatgaagta acgctagagt tggaaaaaga
    11641 gttggaagac accagaaata aacttcccct ctatgcggct attgacaatt atcatggacg
    11701 tattgaaaat ctcattttaa gccaagaaaa ccaggatgat caagaagact gggctgcttt
    11761 gaaactcttg attcttagta ttgaaagtga tggtttggaa caggcctatg aagaggggaa
    11821 cattagcaat cgtgcttacc gagtttacca acgttatctg aaaaatatag aacaaggaat
    11881 caatcgtaaa cttgcctcaa gactgaccta ttattttctt gtttccttga ggattttacg
    11941 ttttctcctt catgaagttt ttactcttgg aaagaccttc cgtagctgga aggacaagga
    12001 gcaaagccgt ctccgtgctc ttgattatga ccaaattgca gagctctatc ttgccaatac
    12061 ggagatgatt attgaaagtt tggaaaacct gaagggagtc tacagacgct ctttgattag
    12121 ttttatgcag gagtctcgtc ttcgagaaac aactattatc agcagtggtg catttgtcga
    12181 acgggttatc aatcgtgtca aacccaacaa tatcaatgaa atgctgagag gctattatct
    12241 ggagcgcaag ttgattttcg aatacgaaga aaaacgatta attacaacta agtatgccaa
    12301 gaaattacga caaaatgtaa ataacttaga gaactattcc ttgaaggaag ctgccaatac
    12361 cctgccgtat gatatggtgg aattggtaag aagaaattag ttaatactct tcgaaaatct
    12421 cttcaaacca cgtcagcgtc gccttaccgt atgtatgtga ctgacttcgt cagtcttatc
    12481 tacaacctca aaacagtgtt ttgagcagct tgcggctagc tttctagttt gctctttgat
    12541 tttcattgag tataagatta taaatgaagg agtatgacat gaaaaagtgg tggaaagagc
    12601 tgatagacaa gcctttatta aaagcttttt tgcattatta tcaagcatca gatagtgagt
    12661 tgaccagtgt cgcagtagcc tactattggt tgatttcgat tttccccctg cttttggtgg
    12721 tggtcaatat cctcccctat tttcagattc ctgtgggaga atttctgggc tttatgaaag
    12781 acgtcctgcc cccaagcctc tatgaaggtg tggaaaaaat agccagagaa gtcttgacgc
    12841 aaccttcaac aggtttattg agtttttctg ttttatcggc gttatggagt ttttcaaaat
    12901 ctataaattt cttgcaaaaa gcttttaaca aggcttatgg cgtcgaaaag agtcgtggac
    12961 ttatttccca tcagatgcta agtctcctag tcagttttgg cttgcagttc ctctttgcgt
    13021 ttgccttgtt tttgatctta tttggtcaga tgattttggc tttacttgct cattattgga
    13081 caaaagatgg cattatctat caggctttac aagggttggc aggtcctctg atttacgccc
    13141 tcctctttgc tatcttggtc atgctttatt attttcttcc caatctatct aacaggaaaa
    13201 ttagctatac cctaccaggc agtgcctttg ttctcttggt gattttaggt gtactaactc
    13261 tgttctctag ttatctcaat tactatgtcc atcatttggt ggatgtccga attttaggtt
    13321 ccgttcttct tgttgttatg atgttttggt ttatcttgat tgctaaaatt gttatcctag
    13381 gcgcggtgat caatgccagt atgcagagtt tgaaagatca ggtctttaaa aaagactaac
    13441 tatttatcca ttacaaaagc gcatagtatc aaggctttat agaatcttga tactatgcgc
    13501 ttttgtgctt tgacagtttt ttgtatagtt tttgtccaag atttctaaat catctgatta
    13561 aattcctatt ttcccctatc attgtccctg ttttttcgaa aatggaagga gtataataaa
    13621 tctatcaata aaatgatagg aggaacttta tgggtcatat tttctttttt ctaagtgtct
    13681 ttttggcagg gattctatcc ttcttttctc cttgtatctt acctttgtta ccggtctata
    13741 caggagtgtt actagatgat aaggatggtg ctcaggcttc tagcggcaaa ttttcaatct
    13801 cagttactag tttattacga actctggcct ttatagcagg aatttccttt atatttattt
    13861 tgttgggcta tggagctggt tttttaggcg atttgcttta tgcttcttgg ttccaatatc
    13921 ttactggggc aattattatc cttcttggtt tgcaccaaat ggagattcta cactttaagg
    13981 ggctttataa ggaaaagagg ctacaactgc aaggacaggg gcaaaatggt aagggctata
    14041 gtcaggcatt tttattgggc ttgaccttta gttttgcttg gacgccttgc gtggggccgg
    14101 ttctggggtc tgttttggcc ttggcggctt caggtggttc aggagcttgg cagggagctg
    14161 gtctcatgtt ggtgtatacg ctgggcttgg cgctaccatt cttgcttcta gctctgacct
    14221 ctagttatgt tttgaaacat ttccgaaaac ttcatcccta tctcggaatc ctcaaaaaag
    14281 tgggtggttt tctcattatt gtgatgggat tcttggttct gtttggaaat gcttcaattt
    14341 taagtcaatt atttgaataa aatggaaagg aatatcaata tgaaaaaatg gcaaacatgt
    14401 gttcttggag caggttcgct cctttgtttg acggcttgtt caggcaagtc cgtgactagt
    14461 gaacaccaaa cgaaagatga aatgaagacg gagcagacag ctagtaaaac aagcgcagct
    14521 aaagggaaag aggtggctga ttttgaattg atgggagtag atggcaagac ctaccgttta
    14581 tctgattaca agggcaagaa agtctatctc aaattctggg cttcttggtg ttccatctgt
    14641 ctggctagtc ttccagatac ggatgagatt gctaaagaag ctggtgatga ctatgtggtc
    14701 ttgacagtag tgtcaccagg acataaggga gagcaatctg aagcggactt taagaattgg
    14761 tataagggat tggattataa aaatctccca gtcctagttg acccatcagg caaacttttg
    14821 gaaacttatg gtgtccgttc ttacccaacc caagccttta tagacaaaga aggcaagctg
    14881 gtcaaaacac atccaggatt catggaaaaa gatgcaattt tgcaaacttt gaaggaatta
    14941 gcctaggagg cgtcttatga atgataagtt aaaaatcttc ttgttgctag gagtattttt
    15001 tctagccata accggtttct atgttctatt gatacgaaat gcagggcaga cagatgcctc
    15061 gcaaattgaa aaggcggcag ttagccaagg aggaaaagca gtgaaaaaaa cagaaattag
    15121 taaagacgca gacttgcacg aaatttatct agctggaggt tgtttctggg gagtggagga
    15181 atatttctca cgtgttcccg gggtgacgga tgccgtttca ggctatgcaa atggtagagg
    15241 agaaacaacc aagtacgaat tgattaacca aacaggtcat gcagaaaccg tccatgtcac
    15301 ctatgatgcc aagcaaattt ctctcaagga aatcctgctt cactatttcc gcattatcaa
    15361 tccaaccagc aaaaataaac aaggaaatga tgtggggacc cagtaccgta ctggtgttta
    15421 ttacacagat gacaaggatt tggaagtgat taaccaagtc tttgatgagg tggctaagaa
    15481 atacgatcaa cctctagcag ttgaaaagga aaacttgaag aattttgtgg tggctgagga
    15541 ttaccatcaa gactatctca agaaaaatcc aaatggctac tgccatatca atgttaatca
    15601 ggcggcctat cctgtcattg atgccagcaa atatccaaaa ccaagtgatg aggaattgaa
    15661 aaagaccctg tcacctgagg agtatgcagt tacccaggaa aatcaaacag aacgagcttt
    15721 ctcaaaccgt tactgggata aatttgaatc cggtatctat gtggatatag caactgggga
    15781 acctctcttt tcatcaaaag acaaatttga gtctggttgt ggctggccta gttttaccca
    15841 acccatcagt ccagatgttg tcacctacaa ggaagataag tcctacaata tgacgcgtat
    15901 ggaagtgcgg agccgagtag gagattctca ccttgggcat gtctttacgg atggtccaca
    15961 ggacaagggc ggcttacgtt actgtatcaa tagcctctct atccgcttta ttcccaaaga
    16021 ccaaatggaa gaaaaaggct acgcttattt actagattat gttgattaat actcttcgaa
    16081 aatctcttca aaccacgtca gcgtcgcctt accgtatgta gggttactga cttcgtcagt
    16141 tttatctaca acctcaaagc tatactttga gctgacttcg tcagttttat ttacaacctc
    16201 aaagctatac tttgagaaac ctgtggctat cttcctagtt tactttttga tttttattga
    16261 gtataagagg tctttcctaa gcagttagag gagaattttg ctatactgat actagtaagt
    16321 ggtaaaggag cagagcatga cctacacaat cttaatcgta gaagatgaat atctggtaag
    16381 acaaggtttg actaaactgg tcaatgtagc agcctacgat atggaaatca tcggtcaggc
    16441 tgaaaatgga aggcaggctt gggaattgat ccaaaagcag gtgccagata tcattttaac
    16501 cgatatcaac atgcctcatc taaatggcat ccagttggcc agtctggtac gagaaaccta
    16561 tcctcaggtt catttggtct ttttaacagg ttacgatgat tttgattatg ccttgtctgc
    16621 tgtcaaacta ggtgtggacg actacctgct caaacccttt tctcgtcagg atattgagga
    16681 aatgttgggg aaaatcaaac aaaaactaga caaggaagag aaagaagagc agttacaaga
    16741 tttattgact aataggtttg aaggaaacat ggcccagaaa atccagtctc atctggctga
    16801 tagccaattt agtttaaagt ctttagccag tgacttaggt tttagtccga cctatctgag
    16861 ttccttgatt aagaaagagt tgggcttgcc ttttcaggat tatctggtga gagaacgtgt
    16921 taaacaagcc aagctcttgc ttttaactac agatctgaag atttatgaga tcgcagagaa
    16981 ggttggtttt gaagatatga actattttac ccaacgtttt aagcagattg caggtgtgac
    17041 acctcgtcag tttaagaagg gagaagaccg atgaagcgtt cttctctttt agttagaatg
    17101 gttatttcca tctttctggt ctttctcatt ctcctagctc tggttggaac tttctactat
    17161 caatcaagtt cttcagccat tgaggccacc attgagggca acagccaaac gaccatcagc
    17221 cagactagcc actttattca gtcttatatc aaaaaactag aaaccacctc gactggtttg
    17281 acccagcaga cggatgttct ggcctatgct gagaatccca gtcaagacaa ggtcgaggga
    17341 atccgagatt tgtttttgac catcttgaag tcagataagg acttgaaaac tgttgtgctg
    17401 gtgaccaaat ctggtcaggt catttctaca gatgacagtg tgcagatgaa aacttcctct
    17461 gatatgatgg ctgaggattg gtaccaaaag gctattcatc agggagctat gcctgttttg
    17521 actccagctc gtaaatcaga tagtcagtgg gtcatttctg tcactcaaga acttgttgat
    17581 gcaaagggag ccaatcttgg tgtgcttcgt ttggatattt cttatgaaac tctggaagcc
    17641 tatctcaatc aactccagtt ggggcagcag ggctttgcct tcattatcaa tgaaaaccat
    17701 gaatttgtct accatcctca acacacagtt tatagttcgt ctagcaaaat ggaggctatg
    17761 aaaccctaca tcgagacagg tcagggttat actcctggtc acaaatccta cgtcagtcaa
    17821 gagaagattg caggaactga ttggacggta cttggcgtgt catcattgga aaagttagac
    17881 caggttcgga gtcagctctt gtggaccttg cttggggcca gtgtcacatc tcttcttgtc
    17941 tgtctctgct tagtgtggtt cagtcttaaa cgctggattg ctcctttgaa ggatttgaga
    18001 gaaaccatgt tggaaattgc ttctggtgct caaaatcttc gtgccaagga agttggtgcc
    18061 tatgaactga gagaagtaac tcgccaattt aatgccatgt tggatcagat tgatcagttg
    18121 atggtagcta ttcgtagcca ggaagaaacg acccgtcagt accaacttca agccctttcg
    18181 agccagatta atccacattt cctctataac actttggaca ccatcatctg gatggctgaa
    18241 tttcatgata gtcagcgagt ggtgcaggtg accaagtcct tggcaaccta tttccgcttg
    18301 gcgctcaatc aaggcaagga cttgatttgt ctctctgacg aaatcaatca tgtccgccag
    18361 tatctcttta tccagaaaca acgctatgga gataagctgg aatacgaaat taatgaaaat
    18421 gttgcctttg ataatttagt cttacccaag ctggtcctac aaccccttgt agaaaatgct
    18481 ctttaccatg gcattaagga aaaggaaggt cagggccata ttaaactttc tgtccagaaa
    18541 caggattcgg gattggtcat ccgtattgag gatgatggcg ttggcttcca agatgctggt
    18601 gatagtagtc aaagtcaact caaacgtggg ggagttggtc ttcaaaatgt cgatcaacgg
    18661 ctcaaacttc attttggagc caattaccag atgaagattg attctagacc ccaaaaagga
    18721 acgaaagttg aaatatatat aaatagaata gaaactagct aactcccagt caattctggg
    18781 agttttatgc gtaattgggc aaactttcta ggttgtctat cttgctaaaa acaagaaaaa
    18841 acggtatgat agaagagtga caacagaggt aacagagatg aacgagacac agattcaaag
    18901 agaaacacgt caggtagtgg aagatgtttt agaaaagacc aatttgaaac agggggccct
    18961 ttttgtttta ggtctatctt ctagtgaggt gctaggtggt cagattggga aagaatccag
    19021 tcaagagatt ggtgagctga tagtggagac tatcttgggt attctaggta gtagaggtat
    19081 ccatttagca gttcaaggtt gtgagcatgt caatcgggct ctcgttgttg aacgtcaggt
    19141 ggcagagcag tttggtctgg aaattgtcag tgtccatcct actcttcatg caggaggttc
    19201 ggggcagttg gcagccttta agtttatgca ggatccagtt gaggttgaat ttatcaaggc
    19261 tcatgctgga ttggatatcg gagacactgc aattggcatg catgtcaagc atgttcaggt
    19321 tccgattcgc cctattttga gagagattgg tcatgcccat gtaacggcac tgactagtcg
    19381 tccaaaatta atcggaggtg cgcgtgcgca ctatccgcaa gatgctatta ggaagttttg
    19441 agaatgaata aaggagataa aagtgtttaa aaaagaccgt ttttcaattc gtaagattaa
    19501 gggagttgta ggctctgtat ttcttggaag ccttttgatg gctccttctg tagtggacgc
    19561 agccacctat cactatgtaa ataaagagat tatttcacaa gaagctaaag atttaattca
    19621 gacaggaaag cctgacagga atgaagttgt atatggtttg gtgtatcaaa aagatcagtt
    19681 gcctcaaaca gggacagaag catctgtttt gacagctttt ggtttgctga ctgttgggag
    19741 cttgctttta atctacaaga gaaagaaaat tgctagcgtc tttctagttg gaactatggg
    19801 attggtagtt cttcctagtg caggggctgt agacccagtt gcgaccctag cactggctag
    19861 tcgagagggt gttgttgaaa tggagggcta tcgctatgtt ggttatctat caggtgacat
    19921 cctcaaaacg cttggcttgg acactgtttt agaagaaacc tcagcaaaac ctggagaggt
    19981 gactgtagtc gaagttgaga ctcctcaatc aacaacaaat caggagcaag ctaggacaga
    20041 aaaccaagta gtagagacag aggaagctcc aaaagaagaa gcacctaaaa cagaagaaag
    20101 tccaaaggaa gaaccaaaat cggaggtaaa acctactgac gacacccttc ctaaagtaga
    20161 agaggggaaa gaagattcag cagaaccagc tccagttgaa gaagtaggtg gagaagttga
    20221 gtcaaaacca gaggaaaaag tagcagttaa gccagaaagt caaccatcag acaaaccagc
    20281 tgaggaatca aaagttgaac aagcaggtga accagtcgcg ccaagagaag acgaacaggc
    20341 accaacggca ccagttgagc cagaaaagca accagaagtt cctgaagaag agaaggctgt
    20401 agaggaaaca ccgaaaccag aagataaaat aaagggtatt ggtactaaag aaccagttga
    20461 taaaagtgag ttaaataatc aaattgataa agctagttca gtttctccta ctgattattc
    20521 tacagcaagt tacaatgctc ttggacctgt tttagaaact gcaaaaggtg tctatgcttc
    20581 agagcctgta aaacagcctg aggtaaatag cgagacaaat aaacttaaaa cggctattga
    20641 cgctctaaac gttgataaaa ctgaattaaa caatacgatt gcagatgcaa aaacaaaggt
    20701 aaaagaacat tacagtgata gaagttggca aaacctccaa actgaagtta caaaggctga
    20761 aaaagttgca gctaatacag atgctaaaca aagtgaagtt aacgaagctg ttgaaaaatt
    20821 aactgcaact attgaaaaat tggttgaatt atctgaaaag ccaatattaa cattgactag
    20881 taccgataag aaaatattgg aacgtgaagc tgttgctaag tatactctag aaaatcaaaa
    20941 caaaacaaaa atcaaatcaa tcacagctga attgaaaaaa ggagaagaag ttattaatac
    21001 tgtagttctt acagatgaca aggtaacaac agaaactata agcgctgcat ttaagaacct
    21061 agagtactac aaagaataca ccctatctac aactatgatt tacgacagag gtaacggtga
    21121 agaaactgaa actctagaaa atcaaaatat tcaattagat cttaaaaaag ttgagcttaa
    21181 aaatattaaa cgtacagatt taatcaaata cgaaaatgga aaagaaacta atgaatcact
    21241 gataacaact attcctgatg ataagagcaa ttattattta aaaataactt caaataatca
    21301 gaaaactaca ttactagctg ttaaaaatat agaagaaact acggttaacg gaacacatgt
    21361 atataaagtt acagcaatcg cagacaattt agtctctaga actgctgata ataaatttga
    21421 agaagaatac gttcactata ttgaaaaacc taaagtccac gaagataatg tatattataa
    21481 tttcaaagaa ttagtggaag ctattcaaaa cgatccttca aaagaatatc gtctgggaca
    21541 atcaatgagc gctagaaatg ttgttcctaa tggaaaatca tatatcacta aagaattcac
    21601 aggaaaactt ttaagttctg aaggaaaaca atttgctatt actgaattgg aacatccatt
    21661 atttgacaag attaaagctg gaactgttaa aaatataaat tttgaaaata ttgatattaa
    21721 tgtgtctaat caagataata tcgcgacaat tgcgaatgaa atcaacggaa ccacacgtat
    21781 agaaaacatc aaagcaactg gaacgataac agccagaaat aacgttgctg gatttgtaaa
    21841 caatatcaaa gaaaatgctg ctctagaaaa cgtagcattt ataggtaata tcaattctgt
    21901 tggtaataat tctacagtcg gaggaattgc tggttcgaac tacatgggat ttgttaataa
    21961 agcttatgtt gatgctaaca ttactgccgc taacgcaagc gcaagtatgc tagttccttt
    22021 ggttacatat atgttaaata gctatcagta tggaactaag tcaaaagtta ccaattcggt
    22081 tgctaaagga actttagatg ttaaaaatac tcgttttgtt ggtggtgttg tagctaaaac
    22141 ttggccttgg ggagttataa aagatattgt tacctatgct aaagtaatta aaggtgaaga
    22201 agtatatggt tcaaacgaaa ttaatgacgg agatgcacgc caattcttat ctgatattta
    22261 tagagtcaac ggcgctagca gtggagctaa taattttacc aatctgcaaa aaataaaaca
    22321 attaactaaa gaacaagctg atgctaaagt tgctactttc aatattactg ctgataaatt
    22381 agaaagtgag ctatctcctc ttgcaaaact taatgaagaa aaagcttatt ctagtattca
    22441 agattacaac gctgaatata atcaagccta taaaaacctt gaaaaattaa taccattcta
    22501 caataaagat tatattgtat accaaggtaa taaattaaat aaagaacacc ctctaaatac
    22561 taaagaagtc ctttctgtta cagcgatgaa caacaatgag tttatcacaa acctagatga
    22621 agctaataaa attattgttc actatgcaga cggtacaaaa gattacttta acttatcttc
    22681 tagcagtgaa ggtttaagta atgtaaaaga atatactata actgacctag gaattaaata
    22741 tacacccaat atcgtgcaaa aagataacac tactcttgtt aatgacataa aatctatttt
    22801 agaaccagta gatcttcaat ctcaaacaat gtatcaacac ctaaatcgat taggtgacta
    22861 tagagttaat gcaatcaaag atttatattt agaagaaagc ttcacagccg ttaaaaagaa
    22921 cttaacaaac ctaatcacaa aattagttca aaatgaagaa caccagttaa atgattctcc
    22981 agctgctcgt caaatgcttc gtgataaagt cgagaaaaac aaagctgccc tattattagg
    23041 tttaacatac ttaaaccgtt actacggtgt taaattcggt gatgttaata ttaaagaatt
    23101 aatgttattc aaaccagact tctatggtga aaaagttagc gtattagaca gattaattga
    23161 aatcggctct aaagagaaca acattaaagg ttcacgtaca ttcgacgcat tcggtgaagt
    23221 attagctaaa tatactaaat caggtaattt agatgtattc ttaaattata atagacaatt
    23281 attcacaaat atagataata tgaatgattg gtttattgat gctacaaaag accatgtcta
    23341 catcgcagaa cgcgcatctg aggtcgaaga aattaaaaat gctaaatata gagcatatgc
    23401 taacttaaac gtagctcagc acagaaaaat gattttacca ttattgaata taactaaatc
    23461 acacatgttt attgcctcta actacaacgc aattgcaatt ggtagtgctg agaaattagg
    23521 aaaaaaatca ttagaagaca ttaaagcatc tgttgattat gctgctgatg ggtacagaaa
    23581 ctactatgat ttttggtatc gtctagttcc agataatgtt aaacaatatc tactaagaga
    23641 tactgtgatt cctatctggg aaggttataa tgcgccaggt ggctgggttg aaaaatacgg
    23701 tcgatataat actgacaatg tatatactcc tcttagagaa ttctttggac ctatagaaaa
    23761 atattatggt tataatggaa caggagcata tgctgcactt tatgataatc caatggatcc
    23821 tcgttctgat gtaagttatg ttgctctaaa tatgattggg gattatggta tttctgtgta
    23881 tactcatgaa acaacacata taaacgatcg taaaatctat ttgggtggtt ttggacgtcg
    23941 tgaaggtact gatgctgaag catttgctca aggtatgtta caactaccag tcccaggaag
    24001 tggatttaac gaatatggtt cattaggtct gaataccgta ttcaaaaaac ctaatgatgg
    24061 taatcaatgg tacgatacag atcctaaatc tcttacaaca cgtgatgata tcgataaata
    24121 tatgcgtggt tacaatgatg ctttaatgct tgtcgatcat ttagaggcag atgctgttat
    24181 taatcaaaat aataaagagt taaatggagc atggttcaag aaaatagata agaaattccg
    24241 agatgccagc caattaaatc agtgggacga aattcgaaat ctaacaactg aagaaaaaga
    24301 taacttaaat attacatcaa ttgatagttt aatagatcaa cagttaatga ctaatagaca
    24361 aattggaaac cgtgtttata aacctgaagt cgttagccaa tacgatcaat caccttatgt
    24421 gggggttgaa atgacagccg gtatctacgg aggtaatact agtaaaggtg ctcctggagc
    24481 tgtttcattc aaacataacg cctttagatt atggggttac tacggatacc ttaacggatt
    24541 cctaggctat acttcgaata aatataaaca acaatctaca aaagatggcg agtcagttct
    24601 aagtgatgaa tatattatca agaaaatatc taataataca ttcaacacta ttgaagaatt
    24661 taaaaaagct tatttcaaag aagttaaaga taaagcaacg aaaggattaa caacattcga
    24721 agtaaatggt tcttccgttt catcatacga tgatttactt acactattta aagaagctgt
    24781 taaaaaagat gctgaaactc ttaaacaaga agcaaacggt cacaaaacag tatctatgac
    24841 taatacagta aaactaaaag aagctgttta taagaaactt cttcaacaaa cagatagctt
    24901 taaaacttct atctttagat aatcgaaatc tctcatctgc tttgcggatg agggttttct
    24961 tattttatgc tatacttaag gtatgcatag aaaaacagtg attgatttta ggactttagg
    25021 ggagagatat acctttaccc agcctattaa agagttgaaa acgagaaatg tagaagaagt
    25081 ggcagatttg ctggcacaag tggaaagcta ccaagagcaa ggttattatg tggtggggta
    25141 tgtcagctac gaggctgcac ctgcttttga ggaaaaatta gcagttcaca aggatcccct
    25201 actgggagag tacctgcttt attttactgt tcatgatagc gtagaaactt cccctattcc
    25261 tctgacttat gaggatattg atttgccctc aaattggcag gaagtaacgt ctgcagcaga
    25321 ctatgaaaag gccattgccc agatacacca tcacttgagg cagggagaca cctatcaggt
    25381 caactacacc gtccaactca agcaaaagtt aagtgccaat ccttttgcca tctacaatcg
    25441 tatggtggta gagcaggagg cgggctacaa tgcctatgtg gaacatgacg agatggcagt
    25501 gatttccatg agcccagagc tcttttttga gcaaaatgat cgcgagttga caacacgacc
    25561 aatgaagggg acgactcagc gtggggtaac tgaccaagaa gatcttgaac aggccagttg
    25621 gttggaacag gatcccaaaa atcgctctga aaatatgatg attgtggacc tcttgcgcaa
    25681 tgatatgaac cgtatttctg aagttgggag cgagcacgtg gagcgtctgt gccaggtaga
    25741 gcagtattca actgtttggc agatgacttc gaccatcaag agtcagttgc gagaggatgt
    25801 ggaccttgtt gaaatcttcc gctcactctt tccttgtggt tccataacgg gtgcaccgaa
    25861 aattgcgaca atggagatta tcaagaactt ggagcctcaa ccgcgtggag tctactgtgg
    25921 aacgattggt ctcttgcttc caaatggacg acggattttt aatgtggcca ttcgtaccat
    25981 tcaacttcac aaaggtcaag ccatttatgg agttggcgga gggattactt gggatagcac
    26041 atgggaatct gaataccgag aggttcatca aaaggcagca gttctttatc gtaaacaagc
    26101 tcgcttccaa ctgattacga caggggaaat cagccagaag aacctgctgt ttgaagatca
    26161 acatctggaa agactgagaa aagctagtcg ttattttgcc tttccttttg atgcagaaga
    26221 cttgggacac aagattgagg aagagtgtca ggattgtgaa gctaatcaag attaccgctt
    26281 gcgaatcagc cttagcaaat ctggagagat agaagtcaat cgtcaagtat taacccctct
    26341 cagtacaagc ttttgtcagg cccaagtctg ccttcaggaa gctgctttga atcaatcctt
    26401 tacctacttt aaaaccactc accgaccgca tttgagccta ggagaacaag agaagattta
    26461 ccacaataag tcaggagaac tgcttgaaac ctctatagga aatttggttc tgaaaatcgc
    26521 tggaaaactc tacacaccgc ctatccgact tggaatcttg ccaggaattt accgtcagca
    26581 tttgctagaa acaggacagg tagaagagaa agtcttgacc ttggcagatt taacccaagc
    26641 agaagctatt tacggctgta atgcagtgag aggcttgtat gaactaagcc ttgaggagaa
    26701 ctagatgaaa ttgatatttt tgcatgggtt agggcagtca gcagagtctt ggaaagaagt
    26761 tcggaatcta ctgacagatt atccttctga ggctatcgag ttatttcctt ctggagttag
    26821 taactatcaa caagctaaag agcgagttta tcagcaccta gctcaagaga cagaaccttt
    26881 tgttttgatt ggattgtcct taggtgctgc cctgacacta gaactttcca gttacgattt
    26941 accaaatctt cgagctttga ttctgtcagg atgcccgctt aaattagcag ggaatatcct
    27001 attttatctt cagttgctga tttttaaact acttcccaaa agagtatttg aaaaacaggg
    27061 agcagacaag actcttatgg tcggagtttc tgaggaattg aagacacttg atttaacgga
    27121 tatagcaggg acttgctcct atccaacctt actaatttgt ggcagcaaag ataaaccgaa
    27181 tcttagttct atgaaagctc tccatagact gttaacagat tcgcagtttc agatcattcc
    27241 tgatggccct catgtcttga ataaggcaaa accaaaggag tttgtagaaa agaccagaag
    27301 tttccttgaa ttgctgaaat aagtttgata aaataatatt gaaatcgata tcataattat
    27361 gggagaaaga aatgaataaa cgtctatttt taaaaatgag tctggtgacg ttgccaattt
    27421 tagccttgtt ttcacaacca gttttggcgg aagaaaacat ccatttttcg agctgtaagg
    27481 aagcttgggc gaatggctat tcggatattc acgagggaga acctggttat tctgccaagt
    27541 tagaccgtga tcatgatggt gtggcttgcg aattgaaaaa tgctcctaag ggtgctttta
    27601 aagcaaaaca gtcaacggct attcaaatca acacaagttc agcaacaaca agtggttggg
    27661 ttaagcagga cggcgcttgg tactactttg atggaaatgg aaatctagtg aaaaatgcat
    27721 ggcagggaag ctattacctg aaagctgatg gtaaaatggc acagagtgaa tggatttatg
    27781 actcttctta tcaagcttgg tattatttga catcagatgg ttcttatgca aaaaatgcat
    27841 ggcaaggagc ttattacctt aaatcaaacg gtaaaatggc acaaggtgag tgggtttatg
    27901 attcttctta ccaagcatgg tattacttga aatcagatgg ttcatatgct cgcaatgcat
    27961 ggcaaggaaa ctactatttg aaatcagatg gtaaaatggc taaaggtgaa tgggtttatg
    28021 atgccaccta tcaagcttgg tattatttga catcagatgg ttcttatgct tacagtacat
    28081 ggcaaggaaa ttactatcta aaatcggatg gtaaaatggc tgtcaatgaa tgggttgatg
    28141 gtggacgtta ttatgttggc gctgacggag tttggaagga aggtcaagca agtacagttt
    28201 cttctagtaa tgatagcaat agtgaatatt ctgctgcttt aggaaaggca aaaagttata
    28261 attcgttatt ccacatgtca aaaaaacgta tgtatagaca attaacttct gattttgata
    28321 aattttcaaa tgatgcagct caatatgcca ttgatcattt agatgattaa cagatactgg
    28381 taggcgaaaa aattccttat aattcattta cgcaaacctt tgcataagtg aatggatttt
    28441 gatatactag tactgtaagc attttcaatt actacacaat gaaaaaggag aatatgatga
    28501 gtcaaaagat tattgggatt gaccttggtg gaacttctat caaatttgca atcttaacaa
    28561 cagtaggaga aatccaagga aaatggtcaa tcaagaccaa cattttggat gagggaagtc
    28621 atatcgttga tgatatgatt gagtctattc aacatcgttt ggacttgctt ggattggcag
    28681 cagcggactt ccaaggcatt ggaatgggat caccaggtgt ggttgaccgt gacaaaggga
    28741 ctgttatcgg tgcctacaac ttgaactgga aaacccttca accaatcaaa caaaagattg
    28801 aaaaagcttt gggcattcca tttttcatcg ataatgatgc caacgtagca gctcttggtg
    28861 agcgctggat gggtgctgga gataaccaac cagacgttgt ctttatgaca ctcggtactg
    28921 gtgttggtgg tggtattgtc gcagaaggca aattgcttca tggtgttgct ggtgcagcag
    28981 gtgaacttgg tcatatcact gttgactttg accaaccaat ctcatgtact tgtggtaaaa
    29041 aaggctgcct tgagacagtt gcttcagcaa cagggattgt caacttgact cgtcgctatg
    29101 ccgatgaata cgaaggcgat gcagccttga aacgcttgat tgataacgga gaagaagtaa
    29161 ctgctaagac tgtctttgat ctcgcaaaag aaggagacga ccttgctttg attgtttacc
    29221 gtaacttctc acgttacttg ggaatcgctt gtgctaacat tggttcaatc ctaaacccat
    29281 caacaatcgt catcggtggt ggtgtgtcag ctgcgggaga attccttcta caaggtgttc
    29341 aaaaagttta cgatgaaaat agtttcccac aagtacgcac atctactaaa ttagctcttg
    29401 caactctagg aaatgacgct ggagttatcg gagcagcatc acttgtattg caataagata
    29461 atgagagagg aaaatgctaa cctagagtta gtaatgttcc tcttttattt tttatgctat
    29521 actagttagg acaatgaatg aggtgaaacg aaatgacaaa agcagatacg atttttaaag
    29581 agaatattga acgcattcta aaggaaggtg ttttctcaga gcaggctcgt cctaagtaca
    29641 aggatgggac tgttgctaat tccaagtatg taactggtgc cttttccgag tacgacttat
    29701 ctaaaggaga atttcctatc acaaccttgc gtcccattgc aatcaaatcc gccatcaaag
    29761 aagttctctg gatttaccaa gaccagtcaa atagcttaga agtgcttaat gacaagtaca
    29821 atgttcacta ctggaatgac tgggaagttg gagacacggg aaccattggt gagcgctatg
    29881 gtgccgttgt taagaaacac gacattatca ataagcttct caaacagttg gaaaccaatc
    29941 cttggaaccg ccgcaatatt atttcgctct gggattacca agctttcgaa gaaacagatg
    30001 ggctgctccc gtgcgccttt cagaccatgt ttgatgtccg ccgtatagat ggagaaatct
    30061 atctggatgc gaccttgacc cagcgctcga atgatatgct ggtggcccac cacatcaacg
    30121 ctatgcagta tgtggctttg cagatgatga ttgccaaaca ttttggctgg aaggttggga
    30181 agttcttcta cttcatcaac aacctccata tctatgataa tcaatttgaa caagctcagg
    30241 aattgctccg tcgggagccg tcaaactgcc aaccacgctt ggttttaaat gttcctgatg
    30301 ggactaattt ctttgatatc aaagcagaag attttgagtt ggtggattat gaccctgtta
    30361 agccacagtt gaagtttgac ctagctattt aaaagaatag aaaaaagaag ttgagaataa
    30421 tcccaacttc ttttgtttct taacgtgata ctcggcgacg agctgctttt ttacggtttt
    30481 cttcgatgaa agctgctttt tgctcttctg gttcgattac tttcttttta aatgcgtata
    30541 ctgcacctgc aacggcagcg acagttcctg cgacacctgt tacaagacct ttagcgaatc
    30601 ctttagccat gagtcttcct cctttatatt ctcaatcagc cagcctcctc aagaggtcac
    30661 atttttctga ctgacctttt tgtgttataa taatagtaac gaaaaaatgg gaatttttca
    30721 aggaaaaaag atgaaaacaa aaataattgt gattgttgga ccgactgctg ttggaaagac
    30781 ggctctagct attgaagttg caaagcgttt taatggcgaa gtggttagtg gagatagcca
    30841 acaagtctat cgaggacttg atattgggac agctaaggct agtccagaag agcaggcagc
    30901 tgttcttcat catttaatcg atgttagaga gataaccgag tcttactcgg cttttgattt
    30961 tgtttcagaa gctaagatga ctattgagga tattcacagc cgtggcaagc tagccattat
    31021 cgccggtggg actggacttt atatccagag cttgctagaa ggttaccacc taggtgggga
    31081 gactcctcat gaggagattt tagcttatcg agctagtttg gagccgtatt cagatgagga
    31141 attagcccat tttgtggagc aagcaggcct tgagattccc cagtttaatc gtcgtcgtgc
    31201 tatgcgtgcc ttagaaattg cccattttgg tcaggatttg gaaaatcaag agaccttgta
    31261 tgaaccgctg attatctgct tggatgatga acgtagtcaa ctttatgagc gtatcaacca
    31321 ccgagtggat ttgatgtttg aggctgggct tttggatgag gccaagtggc tgtttgacca
    31381 ttcccctaat gtacaggctg ctaaaggaat tggctataag gaactctttc cttatttccg
    31441 tggagagcag acctttgagg aagctagtga gagtcttaaa caggcgaccc gtcgttttgc
    31501 caagcgtcag ctgacctggt tccgtaatcg catgcaggtc accttttatc agattggaga
    31561 atctggtgta caagaccgca ttttaagcca gatagaggag tttttagatg attgaaacgg
    31621 agaaaaaaga ggagcgagtc ctgctgattg gtgtggaatt gcagggtatg gacagttttg
    31681 acctctccat ggaagaattg gctagtttag cgaaaacggc aggggcagtc gttgtagata
    31741 gctacagaca aaaacgtgaa aaatatgatt ccaagacctt cgtcggctct ggtaagttgg
    31801 aagagattgc gcttatggtg gatgcagaag aaatcactac tgtcatcgtc aacaaccgtc
    31861 tgaccccaag gcagaatgtc aatctagagg aagttctcgg tgttaaggtc attgaccgta
    31921 tgcagttgat tttggatatc tttgccatgc gggctcgaag ccatgaaggg aagttccaag
    31981 tccacctagc ccaactcaaa taccttttgc ctcgcttggt tggtcagggg attatgctca
    32041 gccgtcaggc agggggaatt ggttcccgtg gtcctggtga aagccagctg gagctgaacc
    32101 gtcgtagcgt tcgcaatcaa atcacggata tcgagcgcca gctcaaggtg gttgagaaaa
    32161 atcgtgcgac tgtcagagaa aaacgtttgg agtctagcac ttttaagatt ggtttgattg
    32221 gttataccaa tgctgggaaa tcaactatca tgaacatctt gaccagtaag acccagtatg
    32281 aagcagatga gctctttgcg actctggatg cgacaaccaa gagtattcat ctgggaggca
    32341 atctccaagt aactttgaca gataccgttg gctttatcca agatttgccg acagagttgg
    32401 tgtccagttt caagtcaacc ttggaagaaa gcaagcatgt ggaccttctg gttcatgtta
    32461 tcgatgctag caatccttac cacgaggaac atgaaaaaac ggttctctcc atcatgaaag
    32521 acctggacat ggaagatatt cctcacttga cgctttataa taaagcggat ttggtggagg
    32581 atttcacgcc tacccaaacg ccatataccc tcatttctgc caagtctgag gacagtcgtg
    32641 aaaacttgca agcattattg ctagataaga ttaaggaaat ttttgaagca tttaccctgc
    32701 gagtgccttt ttcaaagtcc tacaagattc atgatttaga gagtgttgca attctggaag
    32761 aacgtgatta tcaggaagac agcgaagtga ttacaggcta catttccgaa aaaaataaat
    32821 ggaggttaga agaattttat gactgatatt aaagctttgg ctctaaagta tggaggttat
    32881 acaagtctgg acaaggtcta tctggttcag cttctagctg gtaaaacaga gcaggagcag
    32941 ttaacactta ttacacctcc gccaagtgtt gttaatgcct actttgcaga actctatcag
    33001 aaaaagagtc ctcaggctgc gacggattat tttgcagaac tcagtcagga actgaatctt
    33061 tacaatactg agccaagttt caccctagaa aataagcctt ttattcggct taatctgtct
    33121 ggtaaatcct ttggtttttg ttatgatagt gacggccttg gtcggatttt ctctgaaaat
    33181 gaggagaaaa tctcggatga cttgctcttt gaaattgcgc aaattttccc ccatcaatta
    33241 gtctttgaag agtctggtaa gatttacatg aagcctgtcg aggacgagga agttgtcagc
    33301 ctagaaagtc tcacagcttt gactgatttg gaaagattgg ctgatggtcg aaaacgtctc
    33361 aaaggctaca gccaagagga tttattgcaa gaagctgctg ctttttctgg caaacgctat
    33421 ttccgatcgg aaaaccgcac agccatgtta tatattgatt aattagaaag tatcgaatgg
    33481 atattcaatt tttaggaacg ggggctggtc agccctctaa agctcgcaac gtttcaagtc
    33541 tcgccctgaa acttttggat gagattaacg aagtttggct ctttgactgt ggagaaggta
    33601 cgcaaaatcg cattctggaa accacagttc gaccacgtaa gatcagcaaa atctttatta
    33661 cccatctgca tggagaccac atttttggtt tgccaggttt cctttctagc cgtgcctttc
    33721 aggccaatga agagcagaca gatttggaaa tctacggacc tcaaggaatc aagtcatttg
    33781 tcttaaccag ccttcgtgtg tcaggttctc gtctgcccta ccgcattcat ttccatgagt
    33841 ttgaccaaga ttctctagga aaaatccttg agaccgataa attcactgtg tatgcagagg
    33901 agctggacca tactattttc tgtgttggct atcgtgtcat gcaaaaggat ctagaaggga
    33961 cgctggatgc tgaaaaactc aaggctgctg gtgttccgtt cggcccgctt tttggtaaaa
    34021 tcaaaaacgg ccaggatctt gttttggaag acggaactga aatcaaggcg gctgactata
    34081 tctcagcgcc acgtccaggt aagattatca ctattttagg agacactaga aaaaccaatg
    34141 ctagtgtgcg tctggctgtc aatgcagatg tcctagttca tgagtccact tatggcaagg
    34201 gtgatgaaaa aattgctcgt aaccatggtc actcaactaa tatgcaagct gcacaagtag
    34261 cggtagaagc aggtgccaaa cgcctcctac tcaaccatat cagtgcccgt ttcctctcaa
    34321 aagatattag caaactcaag aaagacgctg ccacaatttt tgaaaatgtc catgtggtca
    34381 aagacttgga agaagtggaa atctagcagt cacagaaagg ataagtatgc ctactattct
    34441 cattaccgga gctagcggtg gtctagctca agaaatggtc aaactcctgc ccaatgacca
    34501 actcatcttg cttggtagaa ataaggaaaa attagcccaa ctctacggaa attattccca
    34561 tgcagaattg attgaaattg atattaccga cgattcagcc ctagaagctc tggtaactga
    34621 tctttatctc cgctatggca agattgatgt cttgattaac aacgctggtt acgggatttt
    34681 tgagggattt gaccagattg ctgataaaga cattcaccag atgtttgagg tcaatacctt
    34741 tgccctgatg aatctgtctc gtcaccttgc ggctcgtatg aaggaaagca gcaaagggca
    34801 tatcatcaac atcgtcagca tggcaggtct aatagctact ggcaagtcta gtctttactc
    34861 agcgaccaag tttgcggcta ttggtttttc aaatgctctg cgactcgaac ttatgcccta
    34921 tggagtctat gtgacaacag tcaatccagg tccaatccga acaggatttt ttgaccaagc
    34981 tgacccagat ggaacttatc ttaaatcggt tgaccgcttc ctcttagagg cagatgcagt
    35041 ggctaaaaag attgtcaaga ttataggaaa aaataaacga gaactcaatc tcccgatttt
    35101 gttgaaccta gcccataagt tttatactct ctttcccaag ctagctgata agttggcagg
    35161 ggaaactttt aattataagt aaaaagaacc aatgtgcagg ttgttgctag cctacatatt
    35221 ggttcttatc atttctcaac tatcaaactg aacttcttct agtagatagt cgataaagcg
    35281 ttcgcccatc ttagataggc tggttttctc atgctggata tagaccagct caatcgggtc
    35341 atcaatatcc agtgggatag aaacgatatt gtctccgttt aggttgctgt tcaaaatccc
    35401 tgtcgcaatg gtataaccat ccaaaccaat caagagatta aagagggtgg cacggtcact
    35461 gaccacaatg gatttcttgt ggtgttcttg agaaagaatc tcttctgaaa agtagaagga
    35521 gttgtgcgtc ccttggtcat agctgaggta agggaaattc tccaaatcag acagtttcac
    35581 cttgtctttc tttgccagag ggttggtctt gctgacaaag atatgcggtt gcgctgtgaa
    35641 gagatggtgg gatagcaggt gattgtcatc cagcatcttg gttaaaacat cacggttgta
    35701 actgtttaag aagaggaccc cgacctcact gcggaagttc ttgacgtcgt cgataatctc
    35761 ccaagtccga gtttcacgaa ggaagagttc gtatttctcc atatcgcttt tcttgagcaa
    35821 agagacaaag gcattgacca caaaggcata gtgttgagac gaaacgctaa agagttcgcg
    35881 gtgggcgaca ggatttttat agcgttcctc cagaagctga gtttgctcga caacctgacg
    35941 ggcataagag agaaactcca tcccatcacg ggtcaaggta atacccttgg gattgcggat
    36001 aaagatttca atgcccattt cattttccaa atctcgcact gcattggaga gactgggctg
    36061 agtgataaag agttgcttgg ctgcctcatt catagagcca gtttcgacga ttttgataat
    36121 ataatgtaat tgttgaattc tcatgttttt attgtaccac acttgcctta gaatcgccaa
    36181 agaagatagg aaaataagga gcattgtgtg agtctcttct tgaaaaaaac acaaaatttt
    36241 gctagaatga gtcttatgaa aacattctat gatgtgcagc aattcctcaa acgatttggt
    36301 attattgttt acatgggaaa acgcttatat gatattgaac tgatgaagtt ggaactatct
    36361 cggatttacg atgcagggtt gatggataaa ttagactatc tagaggcaga agcagttctt
    36421 cgcagagagc acaaggtaga attggattat attgagaaaa atggagaaaa gaactaatgg
    36481 ttacttggat tttgtgggca cttatactag caatgttggc gtggatgggc tttaactatc
    36541 ttcgtattcg ccgtgcggct aaaattgtgg acaatgagga gtttgaagcc ttgattcgta
    36601 cgggtcaatt gattgatttg cgcgacccag cagaattcca cagaaaacat atccttcgtg
    36661 cacgcaatat tccttcaagt cagttgaaaa ctagtcttgc agcccttcgt aaagataaac
    36721 ctgtccttct ctacgagaac caacgtgcgc aacgagttac aaatgcagct ctttacttga
    36781 aaaaacaagg tttttctgag atttatatcc tttcttatgg cttggattct tggaaaggga
    36841 aagtgaagac tagctaacct tatttccaaa ttagtcgaat gataggatga agctattgtt
    36901 ttatagtata attaatttgt ataaaattta aagagttctt agaacatgaa agaaaagaag
    36961 aaaaatccac tttttgtggg tatcttgtcg attattcttg gtttgttatt tccaattgta
    37021 ggcctgattt tgggtatcat aggattggtc ttggctattt cataccaaaa agagtcacaa
    37081 ttagagtata aaatagaaaa gattcttaat atcttaggaa ttgtgatttc tgtagttaac
    37141 tggattgtag caatcgcctt aatttttcgg taaataaaag aaaaaagctt tagttttaaa
    37201 gctttttttg ttttatcgac tcatctctaa atagttttta atgatttgta actctttttg
    37261 gttcaaaggg cggtagttac cttctgctaa atctgggttc aatgtgaagt ccccaaattg
    37321 gattcttttg aggctagtca ccttaacacc aaccgagagg aacattttct tgatttgatg
    37381 aaattttcct tctgaaatgg tgatagaggc ttgactgagg gagggacttg cagatagaat
    37441 ctctagtttt gcgggtttac agacagtacc atctaaaaag acaattccct tttgaaaggc
    37501 ttggatatgg tcaggtgtta gaagtccatt aacctcaact tgataagtct tatcgacatg
    37561 atattgggga tggaggagtt ggaagcccaa gggaccgtta tcggtcaaga gaaggagtcc
    37621 tgttgtatct cggtccagtc ggccgacggc atagagcttg tcagactgga tgtcagatgg
    37681 aagcaagtcc atgacggtcg gaagttcctt gtctttgttg gctgtaacga caccagcagg
    37741 tttatgaagc ataagatagg tgtgttcata gccttgaatg attcgatcct gaaaaaggag
    37801 ttcttgtagt cctgtatcga tattttgagc tagggagcgg gctgggcaac catcgactag
    37861 aatttcccct ctgaggagtg cttgcttcat ggcctttcgg ctaacttttt cttgggctaa
    37921 taaattatct aaacgcatac tgtgcctatc ttatcataag tcgcttgctt tgaaaaggct
    37981 tgacgtgaaa agaaaagcgg agtgaaaaca tttacacttg cttgagttat gttatttatt
    38041 tgaaattatg gtataatcgt tcagttagaa aataaatttt gaatattata gaggaaatca
    38101 tgacaaaatt aagagaagat atccgtaaca ttgcgattat cgcccacgtt gaccacggta
    38161 aaacaaccct ggttgacgaa ttattgaaac aatcagaaac gcttgatgca cgtactgaat
    38221 tggcagagcg tgctatggac tcaaacgata tcgaaaaaga gcgtgggatt accatccttg
    38281 ctaaaaatac tgccgttgct tacaacggaa ctcgtatcaa cattatggac acaccaggac
    38341 acgcggactt tggtggagaa gttgagcgta tcatgaaaat ggttgacggt gttgtcttgg
    38401 tcgtagatgc ctatgaagga accatgccac aaactcgttt cgtattgaaa aaagccttgg
    38461 aacaagacct tgtcccaatc gtggttgtta acaaaatcga taagccatca gctcgtccag
    38521 cagaagtagt ggatgaagtc ttggaacttt tcatcgagct tggtgcagat gacgaccagc
    38581 ttgatttccc agtggtttat gcttcagcga tcaacggaac ttcttcattg tcagatgatc
    38641 cagctgacca agaagcgact atggcaccaa tctttgacac gattatcgac catatcccag
    38701 ctccagtaga taactcagat gagcctttgc agttccaagt gtcacttttg gactacaatg
    38761 acttcgttgg acgtatcggt atcggtcgtg tcttccgtgg tacagttaag gttggggacc
    38821 aagttaccct ttctaaactt gacggtacaa ctaaaaactt ccgtgttaca aaactcttcg
    38881 gtttctttgg tttggaacgt cgtgaaatcc aagaagccaa agcgggtgac ttgattgccg
    38941 tttcaggtat ggaagacatc tttgtcggtg aaaccatcac tccgacagat gcagtagaag
    39001 ctcttccaat cctacacatc gatgagccaa ctcttcaaat gactttcttg gtcaacaact
    39061 caccatttgc tggtaaagaa ggtaaatggg taacttctcg taaggtggaa gaacgcttgc
    39121 aggcagaatt gcaaacagac gtttcccttc gtgttgaccc aactgattca ccagataaat
    39181 ggactgtttc aggacgtgga gaattgcact tgtcaatcct tatcgaaaca atgcgtcgtg
    39241 agggctatga acttcaagta tctcgtccag aagttatcgt aaaagaaatc gacggtgtta
    39301 aatgtgaacc atttgaacgt gtacaaatcg acactccaga agaataccaa gggtctgtta
    39361 tccaaagcct ttctgaacgt aaaggtgaaa tgttggatat gatttcaact ggtaatggtc
    39421 aaactcgttt ggtcttcctt gttccagcgc gtggtttgat tggatactca actgagttct
    39481 tatcaatgac tcgtggttac ggtatcatga accatacctt cgaccaatac ttgccattga
    39541 ttccagggga aattggtgga cgtcaccgtg gtgcccttgt ttctatcgat gctggtaagg
    39601 ctacaactta ctcaatcatg tctatcgaag aacgtggtac gatctttgtc aacccaggta
    39661 ctgaggttta tgaaggaatg atcatcggtg aaaactctcg tgaaaatgac ttgacagtta
    39721 acatcacgaa ggcaaaacaa atgaccaacg ttcgttcagc tactaaggac caaacagctg
    39781 ttatcaagac gcctcgtatc ttgacacttg aagagtctct tgagttcttg aacgacgatg
    39841 agtacatgga agtaacgcct gagtctatcc gtttgcgtaa acaaatcctt aacaaagcag
    39901 agcgtgagaa agctaacaag aagaaaaaat cagctgaata agagctagaa agagagaaag
    39961 atggtctatt tagtcctagg aattttactg ctcctactct atgtatttgc gacaccagaa
    40021 agcattaaag ggactgtcaa tatcgtcgct atggtatgta ttttagtggc actcttgatt
    40081 ttattggttc tatcttttct gaaaattttt caattaccaa cagaaatatt cctagcaata
    40141 gccatgttga tcctagctta ctttagtgtt agagacatca cactcatgcc agtcaaaaaa
    40201 agtaaaagaa gataaaaaag agagtttcgg ctctcttttt gctaggaatt ttacaatagt
    40261 ttgaattgct ttttagttaa caccatctct tttacttgta tagtatgaat gggaaaaact
    40321 tgaataaaat tcgttaatgg catctatttt atatttggtt agtactggtt gcat
//
LOCUS       DAVLZG010000009        40297 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLZG010000009 DAVLZG010000000
VERSION     DAVLZG010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.009"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(5..508)
                     /locus_tag="VYO72_000470"
     CDS             complement(5..508)
                     /locus_tag="VYO72_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706908.1"
                     /translation="MTQFQVRISGEAAYYLRMLKEKYETSEGINITKATILTRAFQNS
                     KTVTNWTKVVQDNSISLKNIYPVEEKELKLNVALSDEVAEGIKKYKEILPSATNTQSV
                     TLGVCVKFLLKAELMTQLNHDISEPEKDFDKKFSILEKQLLEIVAPVNHKLLSDTIWN
                     FKNNFIK"
     gene            937..2214
                     /locus_tag="VYO72_000471"
     CDS             937..2214
                     /locus_tag="VYO72_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1706909.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKIDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2290..3774
                     /locus_tag="VYO72_000472"
     CDS             2290..3774
                     /locus_tag="VYO72_000472"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1706910.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGETVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            3835..5115
                     /locus_tag="VYO72_000473"
     CDS             3835..5115
                     /locus_tag="VYO72_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1706911.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5119..5739
                     /locus_tag="VYO72_000474"
     CDS             5119..5739
                     /locus_tag="VYO72_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1706912.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADISRIFETK"
     gene            5905..7083
                     /locus_tag="VYO72_000475"
     CDS             5905..7083
                     /locus_tag="VYO72_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1706913.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVAPSTGTSVPEEQTAETTRPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7596..7934
                     /locus_tag="VYO72_000476"
     CDS             7596..7934
                     /locus_tag="VYO72_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1706914.1"
                     /translation="MTRYQILLFLLEHSLCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7945..8313
                     /locus_tag="VYO72_000477"
     CDS             7945..8313
                     /locus_tag="VYO72_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1706915.1"
                     /translation="MSIITIILTTIVAWEHFYIFYLESIATQSDATSRVFNMEREELA
                     HPSVSLLFKNQGIYKALLGVCLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8442..9038
                     /locus_tag="VYO72_000478"
     CDS             8442..9038
                     /locus_tag="VYO72_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1706916.1"
                     /translation="MSPFEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQP
                     DFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPIRPDGASAYFSSLPIKA
                     MVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVKAGFMHIPYMMEQVVNR
                     PTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9066..9923)
                     /locus_tag="VYO72_000479"
     CDS             complement(9066..9923)
                     /locus_tag="VYO72_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1706917.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10053..11195
                     /gene="tgt"
                     /locus_tag="VYO72_000480"
     CDS             10053..11195
                     /gene="tgt"
                     /locus_tag="VYO72_000480"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1706918.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11296..13113
                     /locus_tag="VYO72_000481"
     CDS             11296..13113
                     /locus_tag="VYO72_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1706919.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13266..14417
                     /gene="nagA"
                     /locus_tag="VYO72_000482"
     CDS             13266..14417
                     /gene="nagA"
                     /locus_tag="VYO72_000482"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1706920.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14580..15638
                     /locus_tag="VYO72_000483"
     CDS             14580..15638
                     /locus_tag="VYO72_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1706921.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15789..16154
                     /locus_tag="VYO72_000484"
     CDS             15789..16154
                     /locus_tag="VYO72_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1706922.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16230..17171
                     /locus_tag="VYO72_000485"
     CDS             16230..17171
                     /locus_tag="VYO72_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1706923.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17119..18135
                     /locus_tag="VYO72_000486"
     CDS             17119..18135
                     /locus_tag="VYO72_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1706924.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18137..18463
                     /gene="comGC"
                     /locus_tag="VYO72_000487"
     CDS             18137..18463
                     /gene="comGC"
                     /locus_tag="VYO72_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1706925.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18456..18860
                     /locus_tag="VYO72_000488"
     CDS             18456..18860
                     /locus_tag="VYO72_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1706926.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18865..19125
                     /locus_tag="VYO72_000489"
     CDS             18865..19125
                     /locus_tag="VYO72_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706927.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19088..19549
                     /locus_tag="VYO72_000490"
     CDS             19088..19549
                     /locus_tag="VYO72_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1706928.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19527..19973
                     /locus_tag="VYO72_000491"
     CDS             19527..19973
                     /locus_tag="VYO72_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1706929.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            20076..20670
                     /locus_tag="VYO72_000492"
                     /pseudo
     CDS             20076..20670
                     /locus_tag="VYO72_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20731..21684
                     /locus_tag="VYO72_000493"
     CDS             20731..21684
                     /locus_tag="VYO72_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1706930.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21735..22925
                     /locus_tag="VYO72_000494"
     CDS             21735..22925
                     /locus_tag="VYO72_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1706931.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADVIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23074..23445
                     /gene="rnpA"
                     /locus_tag="VYO72_000495"
     CDS             23074..23445
                     /gene="rnpA"
                     /locus_tag="VYO72_000495"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1706932.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23420..24244
                     /locus_tag="VYO72_000496"
     CDS             23420..24244
                     /locus_tag="VYO72_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1706933.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24263..25249
                     /locus_tag="VYO72_000497"
     CDS             24263..25249
                     /locus_tag="VYO72_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1706934.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25300..25923
                     /locus_tag="VYO72_000498"
     CDS             25300..25923
                     /locus_tag="VYO72_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1706935.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26054..27511
                     /locus_tag="VYO72_000499"
     CDS             26054..27511
                     /locus_tag="VYO72_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1706936.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27534..27815
                     /locus_tag="VYO72_000500"
     CDS             27534..27815
                     /locus_tag="VYO72_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1706937.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27892..28377
                     /locus_tag="VYO72_000501"
     CDS             27892..28377
                     /locus_tag="VYO72_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1706938.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28394..29059
                     /locus_tag="VYO72_000502"
     CDS             28394..29059
                     /locus_tag="VYO72_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1706939.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29063..29926
                     /locus_tag="VYO72_000503"
     CDS             29063..29926
                     /locus_tag="VYO72_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1706940.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29928..30632
                     /locus_tag="VYO72_000504"
     CDS             29928..30632
                     /locus_tag="VYO72_000504"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1706941.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30811..32484
                     /locus_tag="VYO72_000505"
     CDS             30811..32484
                     /locus_tag="VYO72_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1706942.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32596..33687
                     /gene="ulaG"
                     /locus_tag="VYO72_000506"
     CDS             32596..33687
                     /gene="ulaG"
                     /locus_tag="VYO72_000506"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1706943.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33801..35777
                     /gene="tkt"
                     /locus_tag="VYO72_000507"
     CDS             33801..35777
                     /gene="tkt"
                     /locus_tag="VYO72_000507"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1706944.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGINTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35894..36193
                     /gene="yajC"
                     /locus_tag="VYO72_000508"
     CDS             35894..36193
                     /gene="yajC"
                     /locus_tag="VYO72_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1706945.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36240..36668
                     /locus_tag="VYO72_000509"
     CDS             36240..36668
                     /locus_tag="VYO72_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1706946.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36670..37080
                     /locus_tag="VYO72_000510"
     CDS             36670..37080
                     /locus_tag="VYO72_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1706947.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37380..40031
                     /gene="adhE"
                     /locus_tag="VYO72_000511"
                     /gene_synonym="adhC"
     CDS             37380..40031
                     /gene="adhE"
                     /locus_tag="VYO72_000511"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1706948.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSVHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12316 a         7155 c         8964 g        11862 t
ORIGIN      
        1 agactcattt tataaaatta tttttgaaat tccatatggt atcagaaagt aatttgtggt
       61 tgactggtgc aacgatttca agaagctgtt tttctagaat agagaatttc ttgtcaaaat
      121 ctttttcagg ttctgaaata tcgtgattta attgggtcat caattctgct ttaagaagaa
      181 atttaacaca tacacctaaa gttacacttt gagtatttgt ggcactaggc aatatttctt
      241 tatatttttt aattccttct gctacttcat cggacagtgc aacgttcaat tttaattcct
      301 tttcttccac tggataaata ttttttaaag agatagagtt atcttgtaca acttttgtcc
      361 agtttgttac agtctttgaa ttttgaaacg cacgcgttaa aatggtagct ttagttatat
      421 tgataccttc tgaagtttca tatttctctt ttagcattct taaatagtaa gctgcttcac
      481 cagatattcg gacttgaaat tgtgtcatta ttagtacctc cgtattgtat tataccattt
      541 gtacattaaa aggacaatgt ataaacgaat aatctacctt ctcgttcaag catttttaca
      601 agtttagtaa tcttgttgaa gatgcattcc atgtgttacg tttaaaaaag ggaattaaag
      661 taatctagtt cctaaaaggt tactaaaaat aaaaaaacta tcgtttttgt gatagaggta
      721 actttttgaa aaggctattt gactggcttt atatacttat gaaatgttaa gagcccaact
      781 caaaatccag tgtccgcaag gacgtgccgg ttcgaccccg gccgccggta tagtatagtg
      841 ttaggaacgt tgttattctt cgttcctttt ttatattatt tttggtataa ttatagttat
      901 tcaaatttta tttagattaa gaaagtgtag gggagtatgt cttgttctat cgatttatta
      961 aaacatcggt atttgaaaaa tattaaagaa aatcctgaat tgtttgtcgg aattgagttg
     1021 gagtatcctg ttgcaagttt agaaggggat gctacagatg ttgaagttat aaaggatcta
     1081 tttcattatt tagtttctac tttggatctc accgtagcaa agatagatga ttttggcaat
     1141 ctgatccagt tagtagatcc gataagtcag gatgctattt tatttgaagt ttcctataca
     1201 acgattgagt ttgcatttgg taaggctgaa acgattcaag aggtcgaaaa tcgtttcaat
     1261 aattatatga atgtaattca gagaaagtta gctgaatcaa atcatgctat tgttggctgt
     1321 ggtatccatc ccaactggga taaaaatgag aattgtccag tggcttatcc acgctatcag
     1381 atgttgatgg attatttgaa tttgagtaga aatattatta aatcagattt acatcatttc
     1441 cctgaatatg gtacttttat ctgtgggagc caggttcagc tggatatttc aaaaaccaac
     1501 tacttacggg tgattaatgc ttttactcaa attgaagcgg ctaaggctta tttatttgca
     1561 aactctgagt tttcgggtgc ggattgggat acgaaaattt caagggatat tttctgggaa
     1621 gaatctatgc atggtatcta tccagagaat gttggggtca atgctagact ccttaatgat
     1681 gaagctgatt tttttgacta tctaaatcat tctgcgattt ttactgcgga acgtgatggg
     1741 cagacctatt atttttatcc tattcaggct ggggactatt tggctacgcc tgaaatccaa
     1801 gcattttctc tgaatgggga tgaggttatt atttaccccc aagagaagga ttttgaaact
     1861 catcgtagtt accagtacca agacttaacg actcgaggaa cagttgagtt tcgtagtgtg
     1921 tgtacacagc cacttgatag aacttttgct tctgcagctt ttcacttggg attattggtt
     1981 aatttagaca agttagaagc ttacttagaa acagcacctt tctttaaagt atttggttat
     2041 gattacaagt ctttaaggag acaattttct aagaaaaatc ttacagatga ggaagaaact
     2101 acgattattg aattttccaa agacttactc ctactagctg aggagggact agtggtgaga
     2161 aataaggaag aaatgaccta tttacagcct ttgagagaag aattgagcct ataatttctc
     2221 ttataaaggg agaattttct gaaaaatcat gatataatgg acgagactat agataaagga
     2281 tagagagtaa tgacattagt ttatcaatca acgcgtgatg ccaacaatac agtaactgcc
     2341 agtcaagcaa ttttgcaagg tttggcgacg gacggcggtt tgtttacacc ggttacttat
     2401 ccaaaggtag atttggactt tgacaaattg aaagatgctt cttaccagga agttgctaag
     2461 ctagttttgt cagcattttt agatgacttt acagctgagg agttggacta ctgtatcaac
     2521 aatgcctacg atagcaaatt tgatactcca gctattgcac cattagtgaa attagatggg
     2581 caatacaatt tggaactttt ccatggttca acgattgcct ttaaggatat ggccttgtct
     2641 attttgccat actttatgac gactgctgct aagaaacatg gtttggagaa caagattgtt
     2701 atcttgacag cgacatctgg tgacacgggg aaagctgcta tggcggggtt tgcggatgtg
     2761 cctggtactg agattatcgt cttttatcca aaggatggtg tcagcaagat tcaagagtta
     2821 caaatgacca ctcagactgg cgacaatact catgttattg ctattgatgg taactttgac
     2881 gatgcgcaaa caaatgtgaa gcacatgttt aacgatgtgg ctcttcgtga aaaattgact
     2941 accaacaagt tgcaattttc atcagctaac tctatgaaca ttggtcgtct ggtgccacaa
     3001 attgtttatt atgtttatgc ttacgctcaa ttggttaaga ctggtgaaac tgtagctggt
     3061 gaaaaggtta acttcacagt accaacagga aactttggaa atatcttggc tgccttttat
     3121 gccaaacaaa ttggtttgcc agttggtaaa ttgatctgtg cttcaaatga caacaatgtt
     3181 ttgacagact tctttaaaac acgtgtctat gacaaaaaac gtgagtttaa ggtaacaacc
     3241 agcccatcta tggatatctt ggtatcttca aacttggagc gcttgatttt ccatcttttg
     3301 ggaaataatg ctgaaaagac agctgaactc atgaatgctt tgaacatgca aggacaatat
     3361 aagttgacag actttgatgc agagattttg gacctctttg cagctgaata tgcgactgag
     3421 gaagaaacag cggcagaaat caagcgtgtt tatgagttag attcttatat tgaggatcca
     3481 catacggcgg ttgcctcagc agtttataga aaataccaag cggttactga tgatgcgact
     3541 aagacagtga ttgcttcaac agctagtccc tacaagttcc cagtagttgc agtagaagct
     3601 gtaactggaa aagcaggttt aacagacttt gaagctttgg ctcaattaca tgaaatctca
     3661 ggcgttgcag tgccaccagc agttgatggg cttgagacag ctcctgttcg tcacaagaca
     3721 acagtggcag ctgctgacat gcaagtagcg gttgaggctt atttaggact ttaagataga
     3781 gggagtaaac tcggttggga aaccaactga gtttcttttc atcaggagga gagattgttt
     3841 aagaaaaata aagacattct taatattgca ttgccagcta tgggtgaaaa ctttttgcag
     3901 atgctaatgg gaatggtgga cagttatttg gttgctcatt taggattgat agctatttca
     3961 ggggtttcgg tagctggtaa tattatcacc atttatcagg cgattttcat cgctctggga
     4021 gctgctattt ccagtgttat ttcaaaaagc atagggcaga aagaccagtc gaagttggcc
     4081 tatcatgtga ctgaggcgtt gaagattacc ttactattaa gtttcctttt aggatttttg
     4141 tccatcttcg ctgggaaaga gatgatagga cttttgggga cggagaggga tgtagctgag
     4201 agtggtggac tgtatctatc tttggtaggc ggatcgattg ttctcttagg tttaatgact
     4261 agtctgggag ccttgattcg tgcaacgcat aatccacgtc tgcctctcta tgttagtttt
     4321 ttatccaatg ccttgaatat tcttttttca agtctagcta tttttgttct ggatatgggg
     4381 atagctggtg ttgcttgggg aacaattctg tctcgtttgg ttggtcttgt gattttgtgg
     4441 tcacaattaa aactgcctta tgggaagcca acttttggtt tagataagga actgttgacc
     4501 ttggctttac cagcagctgg agagcgactt atgatgaggg ctggagatgt agtgatcatt
     4561 gccttggtcg tttcttttgg gacggaggca gttgctggga atgcaatcgg agaagtcttg
     4621 acccagttta actatatgcc tgcctttggt gtcgctacgg caacggtcat gctgttggcc
     4681 cgagcagttg gagaggatga ttggaaaaga gttgctagtt tgagtaaaca aaccttttgg
     4741 ctttctctgt tcctcatgtt gcccctgtcc tttagtatat atgtcttggg tgtaccatta
     4801 actcatctct atacgactga ttctctagcg gtggaggcta gtgttctagt gacactgttt
     4861 tcactacttg ggacccctat gacgacagga acagtcatct atacggcagt ctggcaggga
     4921 ttaggaaatg cacgcctccc tttttatgcg acaagtatag gcatgtggtg tatccgcatt
     4981 gggacaggat atctgatggg gattgtgctt ggttggggct tgcctggtat ttgggcaggg
     5041 tctctcttgg ataatggttt tcgctggtta tttctacgct atcgttacca gcgctatatg
     5101 agcttgaaag gataggaaat gcaaaaaaca gcttttattt gggatttaga cgggacttta
     5161 ttggactctt acgaagcgat tttatcaggg attgaggaga cttttgctca gttttctatt
     5221 ccttatgata aggagaaggt gagagagttt atcttcaagt attcggtgca aaatttgctt
     5281 gtgcgggtgg cagaagatag aaatctggat gttgaggtgc taaatcaggt gcgtgcccag
     5341 agtctggctg agaagaatgc tcaggtagtt ttgatgccag gtgcgcgtga ggtgctagct
     5401 tgggcagacg aatcaggaat tcagcagttt atatatactc ataaggggaa caacgctttt
     5461 accattctca aggacttggg ggtggaatcc tattttacag agattttaac cagtcagagt
     5521 ggctttgtgc ggaagccaag tccagaagcg gctacctatc tgctagataa gtatcagctg
     5581 gatcctgaga agacctatta tataggggac cggactttag atgtggaatt tgccaagaat
     5641 agcggtattc aaagcatcaa ctttttagaa tcttcttttg aaggcaatca caggattcaa
     5701 gcactagcag atatttcccg tatttttgag actaagtgat aaaaagattg tgtcagtttt
     5761 gtgacagaga cctaacaaac tatttcaagt aatctagttt gttacaagga atagacagtt
     5821 ctgttaaata ggcccgagag ggcttttttt ctacattttt tgtgttatga tagacaggta
     5881 ctcatttgaa aggaatttga aagaatgaag aaaagaatgt tattagcgtc aacagtagcc
     5941 ttgtcatttg ccccagtatt ggcaactcaa gcagaagaag ttctttggac tgcacgtagt
     6001 gttgagcaaa tccaaaacga tttgactaaa acggacaaca aaacaagtta taccgtacag
     6061 tatggtgata ctttgagcac cattgcagaa gccttgggtg tagatgtcac agtgcttgcg
     6121 aatctgaaca aaatcactaa tatggacttg attttcccag aaactgtttt gacaacgact
     6181 gtcaatgaag cagaagaagt aacagaagtt gaaatccaaa cacctcaagc agactctagt
     6241 gaagaagtga caactgcgac agcagatttg acaaccaatc aagtgaccgt tgatgatcaa
     6301 actgttcaag ttgcagatct ttctcaacca attgcagaag ctccaaaaga agtagcatca
     6361 aattcagaag ttgcagagac agtgactgct gcagaagaag tggcaccatc tacgggcact
     6421 tctgtcccag aggagcaaac ggccgaaaca actcgcccag ttgaagaagt agctcctcag
     6481 gcaacgactc tagctgagaa gcaggaaaca caagtgagct ctcaaaccga gtcagcagtg
     6541 gaagcaacta caatgccagt agaagaaaaa gcaaccgaaa caactgcaac aagttcagaa
     6601 gcaaaagaag tagcatcatc aaatggagct acagcagcag tttctactta tcaaccagaa
     6661 gagacgaaaa caatttcaac aacttacgag gctccagctg cgcccgatta tgctggactg
     6721 gcagtagcga aatctgaaaa tgcaggtctt caaccacaaa cagctgcctt taaagaagaa
     6781 attgctaact tgtttggcat tacatccttt agtggttatc gtccaggaga cagtggagat
     6841 cacggaaaag gtttggctat cgactttatg gtaccagaaa gttcagaatt aggggataag
     6901 attgcggaat atgctattca aaacatggcc agccgtggca ttagttacat catctggaaa
     6961 caacgtttct atgctccatt cgatagcaaa tatgggccag ctaacacttg gaacccaatg
     7021 ccagaccgtg gtagtgtgac agaaaatcac tatgaccacg ttcacgtttc aatgaatgga
     7081 taaacccgac ttggtaacat cattttgacg aatgagatct agctttcgtg ataggaagcg
     7141 attctcgttc gttttttctt tgtcatactc ttcgaaaatc tcttcaaaca acgtcagttt
     7201 tatctgaaac ctcaaagctg tgctttgagc aacctgcgac tagcttccta gtttgctttt
     7261 tgattttcat tgagtatcaa tttgaatgga aaatggaaag ttatcatctt gtaatgagtt
     7321 aagcaacatt cttgcaatct attttatagt agattgaaac tagaatagta cacaactgct
     7381 tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttgtcctg ctcttatttc
     7441 atttcactat actttatatt ataattgact ggtcaaatat tgataaatca ataaaaagag
     7501 aggggaagaa atgctagaga ttcaagattt actgtatcaa ctccgcttgt ctgagcaagt
     7561 gagtacgcaa ttgtttgaaa aagcttggga ttagtttgac acggtatcag attttactgt
     7621 ttttgctgga gcattctctt tgtaaccaaa tggcggttca ggagcgtttg aaaattgatc
     7681 aggctgcttt gacacggaat ttcaagattt tggaaacgga aggtttggtg gagcgtcatc
     7741 gtaatcctga aaatcagcgg gaagtattgg tagaggctgc gaagtatgcc aaggagcagt
     7801 tagtggtgaa tccccctctg caacatatca aggttaagga agagatggaa agtatcttaa
     7861 cagagtttga gagaacagaa ctcagccgtt tattaaataa attggttttg ggtattgaaa
     7921 atatagaaat ttaaggagaa atagatgtca attattacaa ttattttaac aacgatcgtt
     7981 gcttgggagc atttttacat tttttattta gaaagtattg ccacgcaatc agatgcgact
     8041 agtcgtgtat ttaatatgga aagggaagaa ttggctcatc cgtcagtaag tttattgttc
     8101 aaaaatcaag ggatttataa ggctctgcta ggagtctgtc tcttgtatgg catttatttc
     8161 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8221 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8281 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8341 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ttcattgaat
     8401 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct tttgaggcca
     8461 ttaaaggttt accagctgaa atccatggtg ctgaggtccg ttggctagag gtgccgacag
     8521 tttttcacaa atctgctcaa gtattggaag aagagatgaa tcgttatcaa cctgactttg
     8581 tcctttgtat tgggcaagct ggtggaagaa ctagtttgac acctgaacga gtggccatta
     8641 atcaagacga tgcacgtact tctgataacg aagataatca accgattgac cgtcccattc
     8701 gcccagatgg tgcttcggcc tactttagta gtttgccgat taaagcgatg gttcaagcta
     8761 taaaaaaaga gggcttaccg gcctctgttt ccaatacggc agggactttt gtctgcagcc
     8821 atttgatgta tcaggctctc tatttggtag aaaagaaatt tccatatgtt aaggcaggtt
     8881 ttatgcatat tccttatatg atggaacagg tggtgaacag accgactact ccagctatga
     8941 gtttagtgga tattcggcga gggatagaag cagcaatcgg cgctatgata gaacatggag
     9001 atcaggaact caagttggta ggcggagaaa ctcattgata gaaaaaagct tgaggggaaa
     9061 aaccttcaag cttttggacg ttttcgagcc aatactgctc ggtaaaacat aattttagtg
     9121 cattggatat aaggtaggag tgaaaaacta gcaatgccaa aggtaatcca attgaggaag
     9181 taccaaggaa gaagctgtaa atctaggaca aagcgctgga acttgtagcc cttcataaag
     9241 gaacggctag tttttaggat tcgtcttggt gggacctgtc ctaggtctag actataacag
     9301 agaagaaatt ccacctgtga ataggcataa tactgtggaa tatagaggat atttcctaca
     9361 atgatcaaga tgagacttgc aagaaagtag agtccaaaga ccatgaggaa acgctcggtt
     9421 tcaactgatg agagatctag atttggaaac tcaggatgta gggtgacgaa ttttttggct
     9481 aaaaagctac tataaaagag gaggtaaatc ccaagtaaat tagggatact ccataaaaag
     9541 agatagaaac gtttgagaag tagggtcaaa aaggtttgag aaaagcgctc ctcatcaaag
     9601 agagctaggc tgttttttac agatggctcc gttttagaat ctttcatgag tgtcagtgtt
     9661 gcatagacgg aactggtcaa aagaatagtc ccgataaagg agactagtag aggaaagagg
     9721 taggtttgaa gtatttggcc aagtatgctg aaaaatggct gttctaaaac agtcccgtgg
     9781 atccgagata agggattaag aaaactagat aagatgacca gcatactggg aaggatatag
     9841 aggagaaaga gacggggggt gtcagcctga aaatgttttg actcctgacg aattgttttt
     9901 aaatcaattt ttggatagtt cattctctta ttataccata gttcttatac atagttcgtg
     9961 acagttccta ctttttttga taaaatcata cagtgtgtcc ttgggcacac tgtatgaact
    10021 gggactgtct ttcccagctt cggaggtaaa aaatgtcaga ttcaccaatc aaatatcgtt
    10081 tgattaagaa agaaaaacac acaggagctc gtctaggaga aatcatcact ccccacggta
    10141 cctttccgac acctatgttt atgccagttg ggacacaagc cactgtcaaa actcagtcac
    10201 ctgaagaatt gaaggagatg ggttcgggaa ttatcctatc aaacacctat catctctggc
    10261 ttcgccctgg agatgaactc attgcacgcg ctggtggtct ccacaagttc atgaattggg
    10321 accagcctat cttgacagat agtggtggtt ttcaggttta ttctttagca gatagccgta
    10381 atatcacaga agaaggagta acctttaaaa atcatctaaa tggttctaag atgctcctat
    10441 ccccagaaaa agccatctct attcagaata atctgggttc agacatcatg atgtcctttg
    10501 atgaatgtcc tcagttttat caaccttatg actacgttaa gaaatcgatc gagcgtacca
    10561 gccgttgggc tgagcgtggt ttgaaggctc accgtcgtcc acatgaccaa ggtttgtttg
    10621 gaattgtgca aggtgcagga tttgaagacc ttcgccgcca atcagctcat gatcttgtca
    10681 gcatggattt ctcaggctac tctatcggtg gtttggcagt gggagaaacc catgaagaga
    10741 tgaatgcggt cttggacttt acaactcaac tgctgcctga aaataaacct cgttatctga
    10801 tgggtgtggg agcgccagat agcttgatcg atggggtcat tcgtggggtg gatatgtttg
    10861 actgtgtctt accgactcga attgctcgta acgggacttg tatgaccagt caaggacgtt
    10921 tggttgtgaa aaatgcccag tttgctgagg actttacgcc actggatcct gagtgtgatt
    10981 gctacacatg taataactat acacgcgctt accttcgtca cctgctcaag gctgatgaaa
    11041 cctttggtat ccgcttgact agctaccaca atctttactt cttgcttaac ctgatgaagc
    11101 aagtgcgaca agccatcatg gatgacaatc tcttggaatt ccgtaagtat tttgtggaaa
    11161 aatatggcta taataagtca ggacgtaatt tctaaaatgg aattgatata agctaaaaat
    11221 cctaagtttt ctcttaggat ttttcttctt tttttgatag aataaagtgt acaatgaaag
    11281 gaagaataaa ctcgtatgcg cattaaatgg ttttccttgg ttaggattac aggtttactt
    11341 ttggtactct tgtatcactt ctttcagacg atctttcctg gaggattttt cggggtagat
    11401 gtctttttca cattttcagg tttcctgatt acagctctac tcattgaaga attttctaaa
    11461 aaccatgaga ttgatttgat aggatttttt agaagacgct tttatcggat tgtgccacct
    11521 gtggttttga tggtcttggt gaccatgcct tttactttct tggttcgcca agactatgtt
    11581 gctggaattg gtggccagat tgcgagcgtc ttaggcttta tgaccaactt ctatgaactc
    11641 ctaacaggtg ggagttatga atctcagttc attcctcatt tgtttgttca taattggagt
    11701 ttggcagttg aggttcacta ctatattctt tggggattgg cagtttggtt cttatccaaa
    11761 caagctaaat caaatggtca gttgaagggg atggtctttc tcttatctgc tgttgccttc
    11821 ttgatcagtt tcttctccat gtttattggt agttttctag tgacctctta ttcctctgtt
    11881 tatttctcca gtttaactca tgtctatcca ttctttttgg gaagtatgtt agcaactatt
    11941 gtaggcgttc gtcagacgac ttccctcgtc aagcagttgg ataaaatctg ggatttacga
    12001 aagactttgg tagtttttgg aggaggcttt ggtttcctag ttcttttgac tttctttgtc
    12061 aaattcactt atctttttgc ctatcttatc ggcttcttac ttgccagtct tgcagctctt
    12121 gccatgattc tggcggcgcg tgtcttacat gaaaagacac atcatataca ggagccgaag
    12181 attatcagct ttttagcgga tactagctat gcggtttatc ttttccattg gcctttctat
    12241 atcattttct cacagttgac atcaaatctt cttgctgtat tactgactct gatttgttct
    12301 tatggctttg ccagtctgtc attctatgta ttggaacctt ggattgcagg caagaacaca
    12361 cctattgtcc aaacccttcg tcccctgcct tatattcacg caattcttgc agcaggtaca
    12421 ggaatcttga ccatcattgt ctgcacggtg accttgttgg caccacaagt gggagcgttt
    12481 gagacagact tgactgtcaa tggcttgaag caagctgcaa caaatattgg ccagaccaag
    12541 gtgatggcag aacgggcaga tgcaaacagt ttgggaattg ctgatggcac tatgttaatt
    12601 ggtgactcag tggctttaag ggcaaataca gcactacaga cagctcttcc tggagcacag
    12661 attaacgcgc aggtcagcgt aacaaccaag accgcaaatg aaatcatgct aaataatagc
    12721 cagaataaat ttttacctaa gacggtggtc attgcgactg gggtaaataa tcctgagaat
    12781 tacaaggatg actgggacag tatcgtgaaa aatcttccta agggacacca tatgattttg
    12841 gtgactcctt atgagggaga taagacaaaa gagacctatg ccatcgttga gaaggctgct
    12901 gcctatatga gagaattggc agagaagaca ccttacatta cgatagcaga ttggaatcaa
    12961 gttgcgaaag agcatccaga aatttgggca ggaacagacc aggttcattt cgggagtgag
    13021 agtagcacta tcgaagcagg agcaaaattg tatgcagata cgattgccac agctttgcag
    13081 acagctcaag acaagccggt taaatcaaaa taacttgtat taaaaaagag aagagttgga
    13141 gaaatccagc tcttttaaaa tatctccaaa aaataggtct ataccattta caaataaaaa
    13201 agaaaggttt ataatgtaat tgacataata aattgtagaa tcaatctttt aaggaggtta
    13261 acattatgcc taactatatt aaagcggatc agtttttcta cccacacgga gttcgtcgag
    13321 gtggttactt ggaacttgtg gacggcaagt ttgggaaaca tgtagagcag attcctgaag
    13381 gggctgaggt gattgactat acaggttata gcattgcccc aggtcttgtg gatactcata
    13441 ttcatggata tgcaggtgta gatgtgatgg acaacaacat tgaaggtaca ttgcatacta
    13501 tgagtgaagg acttcttagt accggtgtta ccagtttctt acccacaact ttaacagcca
    13561 cttatgagca attgcttgca gtcactgaaa atcttggaaa ccattataaa gaagcaacag
    13621 gtgctaagat tcgtgggatt tattatgaag gtccatattt cacagaaact tttaaggggg
    13681 cacaaaatcc aacttatatg agagacccgg gtgttgagga gtttcattct tggcaaaaag
    13741 cggcaaatgg cttgcttaat aaaattgccc ttgcaccaga acgtgatggg gtggaggact
    13801 ttgttcgtac agttacgggc gaaggtgtga cggttgctct tggacattca aacgcgactt
    13861 ttgatgaagc caaaaaagca gtcgatgctg gagcgagtgt ttgggtgcat gcctacaatg
    13921 gaatgcgtgg gttgactcac cgtgaattgg gtatggttgg agccatgtac caattgccac
    13981 atacctatgc agagttgatc tgtgatggcc accacgtaga tccaaaggct tgcgaaattc
    14041 ttatcaaaca aaaaggaaca gaaaacatcg ctcttatcac agactgtatg acagctgggg
    14101 gattggaaga cggagattat atgttgggag aattcccagt tgtcgttgca aatggaactg
    14161 cacgcctcaa atcgacaggt aacttggcag gttctatcct caaactcaaa gatggtttga
    14221 agaatgtggt cgaatgggga attgcgaatc cgcatgaagc agtcatgatg gccagcttca
    14281 acccagctaa atccgttcac atcgatgatg tctgtggcca aatccgtgaa ggctacgacg
    14341 ctgacttcat cgtattagat aaagatttgg aattggtagc aacctaccta gatggcgtaa
    14401 aacgttatca agcataagag agaaagcaga agttagagac taacttctgc ttttttatgc
    14461 agggtacttt actggtaaat aaaaagttaa aaaaatcaca aaaaaagctt gaagaaacaa
    14521 agaaaaaggc ttacaattga actataaata ttacaaataa aaaaacggag gagtgcttta
    14581 tgaaagccta tacttatgtt aaaccaggac ttgcttcttt tgttgatgta gacaaaccag
    14641 ttattcgcaa gccaacagat gctattgtgc gtattgtaaa aaccactatt tgtggaacag
    14701 acctccatat tatcaaaggg gatgttccta cttgccaaag tggtaccatt cttggccacg
    14761 aagggattgg gattgttgaa gaagttgggg aaggagtttc caacttcaaa aaaggtgaca
    14821 aggtcttgat ttcttgcgtc tgtgcctgtg gtaaatgcta ctactgtaaa aaaggaattt
    14881 atgctcactg tgaagacgaa gggggctgga ttttcggtca cttgattgat ggtatgcagg
    14941 ctgaatatct acgtgtccct catgcagata atactcttta ccatactcca gaagacttgt
    15001 cagatgaagc tttggttatg ctgtcagaca ttctgcctac tggatatgaa attggtgtct
    15061 taaaagggaa agtagaacct ggttgcagcg tagccattat tggttcaggt ccagttggat
    15121 tggctgctct tttaacagcc caattctatt caccagctaa attgattatg gtagacctag
    15181 acgataaccg cttggaaact gccctatcat tcggtgcgac tcataaggtt aattcttcag
    15241 accctgaaaa agccattaaa gaaatttatg atttgacaga tggtcgtggt gtggatgtcg
    15301 ctatcgaagc tgttggtatt cctgcaacat ttgatttctg tcaaaagatt atcggtgtag
    15361 acggaacggt tgccaactgt ggtgtgcatg gtaaaccagt tgaattcgat ttagataaac
    15421 tttggattcg caacatcaat gtaacaactg gtttggtatc tacaaatacg actccacaat
    15481 tgttgaaagc acttgaaagt cataagattg aaccagaaaa attggtaact cactatttca
    15541 aactcagtga aattgaaaaa gcctatgaag tcttcagtaa ggcagcagac caccatgcca
    15601 ttaaggtcat tatcgaaaac gatatctcag aagcctaagt agtaaaaata tttttgtaca
    15661 taagtaaata gaaattcagt catccatcag atggctggat tttttatcaa aaaattaaga
    15721 aatgagcata tttctttcct tgtctggcgg aattggttat aatatacggt acaaaggaat
    15781 gaatgaatat gtatcgtgtt atagaaatgt acggagattt tgaaccgtgg tggttcttag
    15841 aaggttggga agaagatatt gtagcaagta gaaaatttga ccagtattat gatgctctca
    15901 aatactacaa aacttgctgg tttagattgg aacaagaatc ccctctttat aaaagtagaa
    15961 gcgacttgat gaccattttt tgggacccgg aagaccaacg ctggtgtgat gaatgtgatg
    16021 agtatttaca acaataccat tctttggctc ttttgcagga tgagcaggtt atcccagacg
    16081 aaaaactacg ctcaggctat gaaaaacaaa ccagtcagga aaggaatcgt tcttgccgta
    16141 tgaaattaaa atagagaaaa gtaacttttt tggagttgct ttttttattt ttctaacgct
    16201 ttgcgaatag tataggtgag gaggtaagta tggttcaaga aattgcacaa gaaatcattc
    16261 gttcagctcg gaaaaaaggg acgcaggata tttattttgt ccctaagtta gacgcctatg
    16321 agcttcatat gagggtagga gacgagcgct gtaaaattgg tagctatgat tttgaaaagt
    16381 ttgcagccgt tatcagtcac tttaagtttg tggcgggtat gaatgtggga gaaaaaagac
    16441 gtagtcaact gggttcctgt gattatgcct atgaccagaa gatggcgtct ctacgtttat
    16501 ctactgtagg cgattatcgg ggacatgaga gtttggttat ccgtttgttg cacgatgagg
    16561 agcaggactt gcatttttgg tttcaggata ttgaagaatt aggcaagcag tacaggcaac
    16621 ggggactcta tctttttgct ggcccggttg ggagtggtaa gacgaccttg atgcatgaat
    16681 tgtccaagtc actctttaaa ggacagcaag ttatgtccat cgaagatcct gtcgaaatca
    16741 agcaggacga catgcttcag ttgcagttga acgaagcaat cggcctaacc tatgaaaatc
    16801 taatcaaact ttccttgcgt catcgaccag atctcttgat tatcggagaa attcgtgaca
    16861 tcgagacggc gcgtgcagtg gtcagagcta gtttgacagg tgcgacagtc ttttcaacca
    16921 ttcacgccaa gagtatccga ggtgtttatg agcgtctgct ggagttgggt gtgagtgaag
    16981 aagaattggc agttgttctg caaggagtct gctaccagag attaatcggg ggaggaggaa
    17041 tcgttgactt tgcaaacaga gattatcaag aacaccaagc agccaagtgg aatgagcaaa
    17101 ttgaccagct tcttaaagat ggacatatca caagtcttca ggctgagacg gaaaaaatta
    17161 gctacagcta agcaaaaaaa tatcatcacc ctatttaaca atctcttttc tagcggtttt
    17221 catctggtgg agactatctc ctttttagat aggagttcct tgttggacaa gcagtgtgtg
    17281 acccagatgc gtacaggctt gtctcagggg aaatcattct cagaaatgat ggaaagtttg
    17341 ggatgttcaa gtaccattgt cactcagtta tctctagctg aagttcatgg caatcttcac
    17401 ctgagtttgg gaaagataga agaatatcta gacaatctgg ccaaggtcaa gaaaaagtta
    17461 attgaagtag cgacctatcc tttgattttg ctgggttttc ttctcttaat tatgctgggg
    17521 ctacggaatt acctgctccc acaactggat agtagcaata ttgccacccg aattatcggt
    17581 aatctgccac aaatttttct aggcatggta gggcttgttt ccgtgcttgc ccttttagca
    17641 ctaacttttt ataaaagaag ttctaagatg agtgtctttt ctatcttagc acgccttccc
    17701 tttattggaa tctttgtgca gacctacttg acagcctatt atgcacgtga atgggggaat
    17761 atgatttcac agggaatgga gctgacgcag atttttcaaa tgatgcagga acaaggttcc
    17821 cagctcttta aagaaatcgg tcaagatctg gctcaaaccc tgaaaaatgg ccgtgaattt
    17881 tctcagacga taggaaccta tcctttcttt aggaaggaat tgagtctcat catagagtat
    17941 ggggaagtta agtccaagct gggtagtgag ttggaaatct atgctgaaaa aacttgggaa
    18001 gcctttttta cccgagtcaa ccgtaccatg aatttggtgc agccactggt ttttatcttt
    18061 gtggcactga ttatcgtttt actttatgcg gcaatgctca tgcccatgta tcaaaatatg
    18121 gaggtaaatt tttaaaatga aaaaaatgat gacattcttg aaaaaagcta aggttaaagc
    18181 ttttacattg attgagatgt tggtggtctt gctgattatc agcgtgcttt tcttgctctt
    18241 tgtacctaat ctgaccaagc aaaaagaagc agtcaatgac aaaggaaaag cagctgttgt
    18301 taaggtggtg gaaagccagg cagaacttta tagcttagaa aagaatgaag atgctagcct
    18361 aagaaagtta caagcagatg ggcgcatcac ggaagaacag gttaaagctt ataatgaata
    18421 ctatactaaa aatggagggg caaatcgtaa agtcaatgat taaggccttt accatgctgg
    18481 aaagtctctt ggttttggga cttgtgagta tccttgcctt gggcttatcc ggctctgtcc
    18541 agtccacttt tgcagcagta gaggagcaga ttttctttat ggagtttgaa gaactctatc
    18601 gggaaaccca aaaacgcagt gtagccagtc agcaaaagac tagtctaaat ttagatgggc
    18661 agacgcttag caatggcagt caaaagttga cagttcctaa aggaattcag gcaccatcag
    18721 gccaaagtat tacatttgac cgagctgggg gcaattcgtc cctggctaag gttgaatttc
    18781 agaccagtaa aggagcgatt cgctatcaat tatatctagg aaatggaaaa attaaacgca
    18841 ttaaggaaac aaaaaattag ggcagtgatt ttactggaag cagtagtcgc tctagctatc
    18901 tttgccagca ttgcgaccct ccttttggga caaattcaaa aaaataggca agaggaagca
    18961 aaaatcttgc aaaaggaaga agtcttgagg gtagctaaga tggccttgca gacaggtcaa
    19021 aatcaggtaa acataaacgg agttgagatt caggtgtttt ctagcgaaaa gggattggag
    19081 gtctaccatg gttcagaaca gttgttggca atcaaagagc cataaggtca aggcttttac
    19141 cttgttagaa tccctgcttg ccctgattgt catcagtggg ggcttactcc tttttcaagc
    19201 tatgagtcag ctcctcattt cagaagttcg ctaccagcaa caaagcgagc aaaaggagtg
    19261 gctcttgttt gtggaccaac ttgaggcaga attagaccgt tcgcagttcg aaaaagtaga
    19321 aggcaatcgc ctatacatga agcaagatgg caaggacatc gccatcggta agtcaaagtc
    19381 agacgatttt cgtaaaaccg atgctagtgg acgggggtat cagcctatgg tttatggcct
    19441 caaatcagct cagattacag aggacaatca actggttcat tttcgtttcc agtttcaaaa
    19501 aggcttagaa agggagttca tctatcgtgt ggaaaaagaa gaaagttaag gcaggtgttc
    19561 tcctctacgc agtcaccata gcagccatct ttagtctttt gttgcaattt tatttgaacc
    19621 gacaaatcgc ccactatcaa gactatgctt taaataaaga aaaattggtt gcttttgcca
    19681 tggctaaacg aaccaaggat aaagccgagc aagaaagtgg ggaacaggtt tttaatctag
    19741 gtcaggtaag ctatcaaaac aagaaaacaa gcttggtgac gactgttcgt acgtctaaga
    19801 gccaatatga gtttctgttt ccttcagtca aaatcaaaga agagaaaaga gataaaaagg
    19861 aagaggtagc gaccgattca agcgaaaaag cggagaaaaa aaatcagaag agaagcctga
    19921 aaagaaagag aattcctagt caattcaact ataatgcgtt gaatccagaa tagtccactg
    19981 tagtttctag aaaattgctg gaaatggatg ttaagctcca attcatttgt ttatatctta
    20041 tttcagttta ctatactttg tgctaaatta aagatatgaa acatgatttt aaccacaaag
    20101 cagaaacttt cgattcccct aaaaatatct tcctcgcaaa cttggtatgt caagcagccg
    20161 agaaacagat tgatcttcta tcagacaaag aaattttaga tttcggtggt gacacgggtc
    20221 tattagcctt gcccctagcc cctagccaag caggctaagt cagtcactct tgtagacatt
    20281 tctgagaaaa tgttggagta agctcgtttg aaagcggagc agcaagcaat caagaatatc
    20341 cagtttttgg agcaagattt accgaaaaat cccttggaga aagagtttga ttgccttgct
    20401 gttagtcggc ttcttcatca tatgcctgat ttggatgcgg atctctcact gtttcatcaa
    20461 catttgaagg aagataggaa actcatcatt gctgatttta ccaagacaga agctaatcat
    20521 catggatttg atttagctga actggaaaac aagctaattg agcatggttt ttcatctgtg
    20581 catagtcaga ttctctatag cgctgaagac ctgtttcaag ggaatcactc agaattcttt
    20641 ttaacagtat cccaaaaatc actcgcctag tcagggagtg atttttctat aaggatggaa
    20701 aaaagaaggg aaatttgata agataggaat atggattttg aaaaaattga acaagcttat
    20761 atctatttac tagagaatgt ccaagtcatc caaagtgatt tggcgaccaa cttttatgac
    20821 gccttggtgg agcaaaatag catctatctg gatggtgaaa ctgagctaaa ccaggtcaaa
    20881 gacaacaatc aggcccttaa gcgtttagca ctacgcaaag aagaatggct caagacctac
    20941 cagtttctct tgatgaaggc tgggcaaaca gaacccttgc aggccaatca ccagtttacg
    21001 ccagatgcta ttgccttact tttggtattt attgtggaag agttgtttac agaggaggaa
    21061 attactatcc tcgaaatggg ttctgggatg ggaattctag gcgctacttt cttgacctcg
    21121 cttgataaaa aggtggatta cttgggaatg gaagtggatg atttgctgat tgatctggca
    21181 gctagcatgg cagatgtaat tggtttgcag gctggctttg tccaaggaga tgccgttcgc
    21241 ccacaaatgc tcaaagaaag cgatgtggtc atcagtgact tgcctgtcgg ctattatcct
    21301 gatgatgccg ttgcgtcgcg tcatcaagtt gcttctagcc aagaacatac ttacgcccat
    21361 cacttgctca tggaacaagg gtttaagtac cttaagtcag atggatatgc tatttttcta
    21421 gctccgagtg atttgttgac cagtcctcaa agtgatttgt tgaaagtctg gttgaaagag
    21481 gaggcaagtc tggttgctat gattagttta cctgaaaatc tctttgctaa tgctaaacaa
    21541 tctaagacta tttttatcct acagaagaaa agtgaaatag cagtggagcc ttttgtttat
    21601 ccacttgcta gcttgcaaga tgcaagtgtt ttaatgaaat ttaaagaaaa ttttcaaaaa
    21661 tggactcaag gtactgaaat ataaaataga ttttgttata atagttgaaa acgcttaaaa
    21721 aggggtatca tgttatgaca aaaacaattg caatcaatgc aggaagttca agtttgaaat
    21781 ggcaattata cttaatgcca gaggaaaaag tgttagccaa aggtttgatt gaacgtatcg
    21841 gtttgaaaga ttcaatttca actgtaaaat ttgacggccg ttctgaacaa caaattttgg
    21901 atattgaaaa tcatacacaa gccgttaaaa ttttattgga tgacttgatt cgtttcgata
    21961 ttatcaaggc ttatgacgag attacaggtg ttggacatcg tgttgttgct ggtggagaat
    22021 atttcaaaga atcaacagtt gttgagggag atgttttaga aaaagttgaa gagttgagtt
    22081 tgttggctcc tctacacaac ccggccaatg cagcaggtgt tcgtgccttc aaggaattgt
    22141 tgccagacat taccagtgta gttgtttttg atacttcctt ccacacaagt atgccagaga
    22201 aagcttatcg ctaccctcta ccaacaaaat attacacaga aaacaaggtt cgtaaatacg
    22261 gtgctcatgg tacaagtcac cagtttgtag caggagaagc tgcaaaactc ttgggacgtc
    22321 cattagaaga cttgaagtta attacctgtc atattggtaa cggaggctca attacagctg
    22381 tgaaagccgg caaatctgta gacacttcta tggggttcac tcctcttggt ggtattatga
    22441 tgggaacgcg tacaggggat attgatccag ctatcattcc ttatttaatg caatatacag
    22501 aggattttaa cacaccagaa gatatcagtc gtgttcttaa ccgtgaatca ggtcttttgg
    22561 gagtttctgc taattctagc gatatgcgcg atatagaagc agctgtagca gaagggaatc
    22621 acgaggctag cttggcttat gaaatgtatg ttgaccgtat ccaaaaacat atcggtcagt
    22681 accttgcagt gctaaatgga gcagatgtca ttgttttcac agcaggtgtc ggtgaaaatg
    22741 cagagagttt ccgtcgtgat gtaatctcag ggatttcgtg gtttggttgt gatgttgatg
    22801 atgaaaagaa tgtctttggc gttacaggag acatctcaac agaggcagct aaaatccgtg
    22861 tcttggttat tccaacagat gaagaattag tcattgcccg tgacgttgaa cgcttgaaaa
    22921 aataagtgaa actaaaaaaa tattcaatac aaggagttgg gaaagttatt tttccagctt
    22981 ctttttctga tgaaattgtc caaaaccttg ctatgattgg cttttttgaa aaatatggta
    23041 taatagtagt aatttaatag atggagttga gttttgaaga aaaactttcg tgtaaaaaga
    23101 gagaaagatt ttaaggcgat tttcaaggag gggacaagtt ttgctaatcg caaatttgtg
    23161 gtctaccaat tagaaaacca gaaaaaccat tttcgagtag gtctatcagt tagcaaaaaa
    23221 ctggggaatg ccgtcactag aaatcaaatt aagcgacgga ttcggcatat tatccagaat
    23281 gcaaaaggga gtctggtaga agatgtcgac tttgttgtca ttgctcgaaa aggagtcgaa
    23341 accttgggat acgcagagat ggagaaaaat ctactccatg tattaaaatt atcaaagatt
    23401 taccgggaag gaaatgggag tgaaaaagaa actaaagttg actagtttgc taggactgtc
    23461 tctgttaatc atgacagcct gtgcgactaa tggggtaact agcgatatta cagccgaatc
    23521 ggctgatttt tggagtaaat tggtttactt ctttgcggaa atcattcgct ttttatcgtt
    23581 tgatattagt atcggagtgg ggattattct ctttacggtc ttgattcgta cagtcctctt
    23641 gccagtcttt caggtgcaaa tggtggcttc taggaaaatg caggaagctc agccacgcat
    23701 taaggcgctt cgagaacaat atccaggtcg agatatggaa agcagaacca aactagagca
    23761 ggaaatgcgt aaagtattta aagaaatggg tgtcagacag tcagactctc tttggccgat
    23821 tttgattcag atgccggtta ttttggccct gttccaagcc ctatcaagag ttgacttttt
    23881 aaagacaggt catttcttat ggattaacct tggtagtgtg gatacaaccc ttgttcttcc
    23941 gattttagca gcagtattca cctttttaag tacttggttg tccaacaaag ctttgtctga
    24001 gcgaaatggc gctacgactg cgatgatgta tgggattcca gtcttgattt ttatctttgc
    24061 agtttatgcg ccaggtggag tcgccctata ctggacagtg tctaatgctt atcaagtctt
    24121 gcaaacctat ttcttgaata atccattcaa gattatcgca gagcgcgagg ccgtagtaca
    24181 ggcacaaaaa gatttggaaa atagaaaaag aaaagccaag aaaaaggctc agaaaacgaa
    24241 ataaataagg aggaatctgg taatggtagt atttacaggt tcaactgttg aagaagcaat
    24301 ccagaaagga ttgaaagaat tagatattcc aagaatgaag gctcatatca aagtcatttc
    24361 tagggagaaa aaaggctttc ttggtctatt tggtaaaaaa ccagcccaag tggatattga
    24421 agcgattagt gaaacgactg ttgtcaaagc aaatcaacag gtagtaaaag gcgttccgaa
    24481 aaaaatcaat gatttgaacg agcctgtgaa gacggttagt gaagaaaccg ttgaccttgg
    24541 tcatgtagtt gatgctatta aaaaaataga ggaagaaggt caaggtattt ctgatgaagt
    24601 caaggctgaa atcttaaaac atgaaagaca tgccagcact atcttagaag aaactggtca
    24661 cattgagatt ttaaatgaac ttcaaatcga ggaagcgatg agggaagaag caggcgctga
    24721 tgaccttgaa actgagcaag accaagctga aagtcaagaa ctagaagact tgggcttgaa
    24781 agttgaaacg aactttgata ttgaacaagt agctacggaa gtaatggctt atgttcaaac
    24841 gattattgat gacatggatg ttgaggctac actttcaaat gattataacc gtcgtagcat
    24901 caatttgcaa attgatacta acgaaccagg tcgtattatc ggctaccatg gtaaagtctt
    24961 gaaggccttg caactgttgg ctcaaaatta tctttacaac tgctattcaa gaaccttcta
    25021 tatcactatt aatgtcaatg attatgttga acaccgtgca gaagtcttgc agacctatgc
    25081 gcaaaaattg gcgattcgtg ttttagaaga aggacgtagt catcaaacag atccaatgtc
    25141 gaatagtgaa cgcaagatta tccaccgtat tatttcacgt atggatggcg tgaccagtta
    25201 ctctgaaggt gatgagccaa atcgctatgt cgttgtagat acagaataag taaaatcagg
    25261 gttgacctga ttttttgcta gctagaggag gttaaactga tgttgaataa gataagagac
    25321 tatttagact ttgctggttt gcagtaccgt aatcctgata aagcgggagc agagcgagag
    25381 aagatgctgg cattccgcca caaaggacaa gaggcccgaa aggcttttac agaactggcc
    25441 aaagcctttc aagcaagcca tccagaatgg caactccaac agactagtca gtggatgaat
    25501 caggcccagc gtttgagacc acatttttgg gtttatctac agagagacgg acaagtgaca
    25561 gaacctatga tggccttacg tttgtatggg acatctactg actttggaat ttctttggaa
    25621 gtcagtttca tcgaacgtaa gaaggatgag caaacactgg gcaagcaggc caaagtttta
    25681 gacattccaa ccgttaaagg gatttattat ctaacctact ctaatggtca aagtcaacgg
    25741 tgggaggcga atgaagaaaa gcgtcgtact ttacgcgaga aggtgagaag tcaagaagtt
    25801 cgaaaagttt tagtgaaggt agatgttcct atgacagaaa attcgtctga agaagaaatc
    25861 gtagaaggct tattgaagtc ttattctaaa attcttccct attatctagc tacgagaaaa
    25921 taagataatt tgtaaaacat cataaatcat acagtccaag agtgaacagt ccgctgtgta
    25981 attcttggtc tttttgtttg cgctttcgca ttatataata aacttacaaa aacaattcaa
    26041 aaggagaaca attatggaag tcgtttcaag tgttctaaat tggttttcta gcaatatttt
    26101 gcagaatccc gcatttttcg taggtttatt ggtgttgata ggatatgcac ttttgaaaaa
    26161 acctgcccat gacgtttttt cagggtttgt taaagcaaca gtagggtata tgttgcttaa
    26221 cgtgggtgct ggtggtttgg ttacaacctt tcgtccaatc ttagcagctc ttaactacaa
    26281 attccaaatt ggtgcagcgg ttatcgaccc ttactttgga cttgctgcag caaacaacaa
    26341 aattgcagca gagtttccag attttgttgg aactgcaact acagctctat tgattggttt
    26401 tggaataaat atcttgctcg tagctcttcg aaagattacg aaggtaagaa ccctctttat
    26461 tactggtcac atcatggtac aacaagctgc aacagtatct cttatggttc tattcttagt
    26521 accacaattg cgcaatgctt acggtacagc agcgattggt atcatctgtg gactttactg
    26581 ggcagttagt tcaaatatga ctgttgaggc aactcaacgc ttgactggtg gtggcggatt
    26641 tgcgattggt caccaacagc aatttgcaat ctggtttgta gataaagtag caggacgctt
    26701 tggtaagaaa gaagaaagtt tagacaatct taaattacct aagttcctct caatcttcca
    26761 cgatacagtt gttgcatctg ctaccttgat gctcgtattc ttcggagcca ttcttttaat
    26821 cttgggtcca gacattatgt ctaataaaga agtcatcact tcaggaactc tattcaatcc
    26881 tgctaaacaa gatttcttta tgtacattat ccaaacagcc tttaccttct cagtttactt
    26941 gttcgttttg atgcaaggtg tccgaatgtt cgtatctgag ttgacaaacg ccttccaagg
    27001 tatttcaaac aaattgttgc caggttcatt cccagcggtt gacgttgcag cttcttatgg
    27061 atttggttct ccaaatgctg tcttgtcagg atttaccttt ggtttgattg gtcaattgat
    27121 tacaattgtc ttgctcatcg tctttaaaaa tccgattctt attattacag gatttgtacc
    27181 agtgttcttt gacaatgcag ccattgcggt ctacgctgat aaacgcggcg gatggaaagc
    27241 ggctgttatc ctttccttta tatcaggtgt ccttcaagtt gctctaggag ctctttgtgt
    27301 ggcccttctc gatttggcat cttatggtgg ctaccatgga aatatcgact ttgaattccc
    27361 atggcttgga tttggatata tcttcaaata ccttggtatt gttggttatg tacttgtgtg
    27421 tctcttcttg cttgttattc ctcaacttca atttgccaaa gcaaaagata aagagaaata
    27481 ttacaacggt gaagttcaag aagaagctta gtatctagaa aaggagaaat aaaatggtta
    27541 aagtattagc agcgtgcgga aatggaatgg gttcatcaat ggttatcaag atgaaggttg
    27601 aaaatgctct ccgtaagctt aatcaaacag attttacagt caattcatgc agtgtcggtg
    27661 aagctaaagg tttagcagta ggatatgaca tcgtaatcgc ttctcttcat ttgattcaag
    27721 aattggaagg gcgaactaat gggaagttaa ttgggcttga taacttgatg gatgataaag
    27781 aaatcaccga aaaactcagt caagcactac agtaaaaggt tggagggggc tggacagaaa
    27841 ctgagagtta tcgtttctgt ccttctccct ctttaaataa aggaggcaga tatgaattta
    27901 aaacaagctt taattgacaa tgactcgatc cgactaggtt tagaggctaa caattggaaa
    27961 gaagcagtca aggtagcagt agatccctta attgaaagtg gggcaatttt gccagagtat
    28021 tacgatgcta tcattgaatc gactgaagag tatgggcctt actatatctt gatgccaggt
    28081 atggctatgc cccacgctag acctgaagct ggtgtgcaaa gtgatgcctt ttcattgatt
    28141 accttacaaa atcctgttgt attttcagat gggaaagagg tatctgtttt gttggcacta
    28201 gcagcaacaa gttcaaaaat tcacacaagt gtagccattc cacaaattat tgccctgttt
    28261 gaattagaag attctattgc acgtttacag gcttgccaga ctaaagaaga tgtcttggct
    28321 atgattgaag aatctaagga tagcccttat ctcgaaggat tggatttgga aagttagaaa
    28381 gaggaataaa gaaatgacaa aaagaatacc taatttacaa gttgcattag accattcaga
    28441 cttgcaagga gcgattaaag cagctgtttc tgttggtcag gaagtagata ttatcgaagc
    28501 tggaactgtt tgcttgcttc aagttggaag tgaactggct gaagtcttgc gtagcctttt
    28561 cccagataag attattgtgg cagacacaaa atgtgctgat gctggtggaa cagttgctaa
    28621 aaataatgcg gttcgtggag cagactggat gacttgtatc tgttgtgcaa ccatccctac
    28681 tatggaagca gctctaaagg ctatcaagac tgaacgagga gaacgaggcg aaatccagat
    28741 cgagctttat ggcgattgga cttttgaaca agctcagctt tggctagatg caggtatctc
    28801 acaagctatt tatcaccaat ctcgtgatgc tcttcttgct ggtgaaactt ggggtgaaaa
    28861 agaccttaat aaggttaaaa aactcattga tatgggcttc cgtgtatctg taacaggtgg
    28921 tctagatgta gatactctca aactctttga aggtgttgat atctttacct ttatcgcagg
    28981 tcgtggaatt acagaggctg cggatccagc aggagcagcg cgtgccttca aggatgaaat
    29041 caaacgaatt tgggggtaaa tcatggtacg tccaattgga atttatgaaa aggcaacccc
    29101 aacacacttt acttggctag aacgtttaaa ttttgccaag gagttaggct ttgattttat
    29161 cgagatgtct attgacgaac gtgacgagcg tttagcaaga cttgactgga gtaaggaaga
    29221 acgcttggaa gttgtcaaag aaatctatga aactggtgtt cgtattcctt ctatctgttt
    29281 ttcaggccat cgtcgctacc cattgggatc aaaagattca gttctagagg aaaaatctct
    29341 agaactcatg aaaaaatgta tcgaattagc tcaagacttg ggagttcgta cgattcaatt
    29401 agctggttac gatgtttact atgaggaaaa gtcaccccag acacgccaac gttttatcaa
    29461 aaatttgaga aaagcctgtg actgggctga agaagctcag gtggtacttg ctattgaaat
    29521 tatggatgat cctttcatca gtagcatcga aaaatatttg gctatagaaa aagagattga
    29581 ctctcccttc ctctttgtat atccagatat tggtaatgtg tctgcatggc ataatgatat
    29641 ctatagtgag ttttatcttg gtcatcatgc catcgcagct ctccatctca aggatactta
    29701 tgcagtgaca gaaagttcaa agggccagtt ccgagatgta cctttcgggc aaggttgtgt
    29761 caaatgggaa gaagctttcg atattttaaa ggaaaccaat tataatggac ctttcctaat
    29821 cgaaatgtgg tctgaaaatt gtgaaacagt agaagaaaca cgcgcagcca ttcaagaggc
    29881 gcaagctttt ctctatccac tcattaagaa agcaggtttg atgtaagatg aatcaagtaa
    29941 tcaatgctat gcgtaaacga gtctgtgatg ccaatcaatc attgccaaaa catggacttg
    30001 tcaaatttac ctgggggaat gtatctgaag tcaatcgcga actcggtgtc attgttatca
    30061 aaccatcagg cgtggattat gacgaattga cacctgaaaa catggtagtg actgatctag
    30121 atggtaagat cctagaaggg gatttaagac catcttccga cctcccaact catgtgcaat
    30181 tatataaggc ttggtcagaa attggtagtg tggttcacac ccattcgaca gaagctgttg
    30241 cttgggctca ggcaggtcgt gatattcctt tctacggaac aacccatgca gattatttct
    30301 acggttcaat tccttgcgcc cgtagtttga ccaaggacga agtagaagtg gcctatgaaa
    30361 aagatactgg cctggttatc gtagaagagt ttgaacatcg cggacttaac ccggttgaag
    30421 taccaggaat tgttgtacgc aatcacggtc cattcacctg gggcaaaaat ccagagaatg
    30481 ctgtttatca ctctgtcgta ctagaggaag tatcaaagat gaatcgcttt acagaacaaa
    30541 tcaatccaag agttggacct gctccccagt acatactaga aaaacactac caacgtaaac
    30601 atggaccaaa tgcttattat ggtcaaaagt aagaacgatg aaggaggaga aaaagataaa
    30661 tttagctcct ctttttacat ttgattttta ttgagagtaa agttggagtt gaagtaattt
    30721 taaaagattt tttagaaata gcgcttgata tatatatggt aaaataaaaa gaattgctgt
    30781 gatatcaata gatttggggg attttttaat atggtactgg ataaggcaag ttgtgatttg
    30841 cttcaatatt tgatggatca agaaacgtcc aaaacgatta tggcgatttc gaaagatttg
    30901 aaagagtcaa gaaggaaaat ttattatcac attgacaaaa tcaatgctgc tctgggtgac
    30961 gaggcgcttc acatcattag tattccacga attggtattc acttaacgga agagcagaga
    31021 gatgcttgtt gtaaactatt atcggaagta gattcgtacg attatatcat gagtgcgcat
    31081 gaacgtatga tgataatgtt actatggata ggtatttcta aagaacgtat tacgattgaa
    31141 aaattgatag agttaacaga ggtatctagg aatactgttc tcaatgattt gaatagtatt
    31201 cgttatcaac taactttgga acaatatcag gtgatcttgc aagtgagcaa gtcacaggga
    31261 taccaccttc atgcccaccc tcttaataaa attcagtatc ttcaatcgct tctatatcat
    31321 atttttatgg aagaaaatgc cacttttgta tctattttag aagataagat gaaagagagg
    31381 ttagatgatg agtgtttgct ttctgttgaa atgaaccaat tttttaagga acaggttcct
    31441 ttagttgaac aagatttagg gaagaaaata aatcatcatg aaataacttt tatgttgcag
    31501 gttctacctt atttgctgtt aagctgtcat aatgttgaac agtatcaaga aagacatcag
    31561 gatatagaga aagaattttc tttgataaga aaaagaatag agtatcaggt gtctaagaaa
    31621 ttaggagaac ggttgtttca aaagtttgaa atttctttgt caggacttga agtttctctt
    31681 gtagctgttc tcctcctctc ctatcgtaaa gatttggata ttcatgcaga aagtgatgat
    31741 tttcggcaat taaaacttgc tttagaagaa tttatctggt attttgaatc acaaatccga
    31801 atggagattg agaacaagga tgatttgtta cgaaatttga tgatccactg taaagccttg
    31861 ttatttagaa agacttacgg tattttttct aaaaatcctc taacaaaaca aattcgatcc
    31921 aagtatggag aattattttt agtcactaga aaatctgcgg aaattttaga aggagcatgg
    31981 tttattcggc taacagacga tgatattgcc tatttgacga ttcatattgg aggattttta
    32041 aagtatacac catcgtctca aaaaaatatg aaaaaagttt atctcgtttg tgatgaaggt
    32101 gttgcggttt cgagactttt gctgaaacaa tgcaaacttt attttccaaa tgagcaaatt
    32161 gacactgtat ttacaacaga acaatttaag agtgtggaag atattgcaca agttgatgta
    32221 gtgattacta ctaatgatga tttggatagc agatttccga ttttaagggt taatcctatc
    32281 cttgaagcag aagatatttt gaaaatgcta gactatctta aacacaatat atttcgtaat
    32341 aagagcaaaa gtttcagtga aaatctttct agtcttattt cgtcttatat tgtagacagc
    32401 aagttggcta gtaagttcca agaagaggtt caaacactta taaatcaaga aatagtagtt
    32461 caagcttttt tggaagatat ttgaaggaca gtccaatgat gaacacaaac ctgtgttttt
    32521 cttggtcttt tttagtgttt tgaagggtgg tatactaatc tcaaagataa caattatatc
    32581 caaaggaggc aacatatgcc aaacgtcaaa gaaattacaa gagagtcatg gattttagcc
    32641 actttcccag agtggggaac atggttgaac gaagaaatcg aagaagaagt cgtacctgaa
    32701 ggcaactttg ccatgtggtg gctaggcaac tgtggtactt ggattaagac accagctggt
    32761 gctaacgttg tcatggacct ttggtcaaac cgtggaaaat caaccaaaaa agtgaaagat
    32821 atggttcgtg ggcaccaaat ggcaaatatg gcaggtgttc gtaaattgca accaaacttg
    32881 cgtgttcagc caatggttat cgatccattt gctatcaacg aactagacta ttacttagtt
    32941 tcacacttcc acagtgatca tatcgaccca tacacagctg cagcaattct caacaatcct
    33001 aagttagagc atgttaagtt tatcggtcct taccactgtg gacgaatctg ggaaggatgg
    33061 ggggttccaa aagaacgtat catcgttgtt aaaccaggtg acactatcga attaaaagat
    33121 atgaagattc atgcagtaga atcatttgac cgtacttgct tggtaactct cccagtgaac
    33181 ggtgctgatg agacaggcgg tgaacttgct ggcttggctg ttacagatga agaaatggct
    33241 caaaaggctg ttaactatat ctttgaaaca ccaggtggaa ccatctatca tggtgcagat
    33301 tctcacttct caaactattt tgcaaaacat ggtaaagact ttaaaattga tgttgctttg
    33361 aataactatg gtgaaaatcc ggtaggtatc caagacaaaa tgacatctat cgaccttctt
    33421 cgtatggcag aaaatctgcg taccaaagtc attatcccag ttcactatga tatctggtct
    33481 aacttcatgg cttctactaa tgagattcta gaactttgga aaatgcgaaa agatcgcttg
    33541 caatacgatt tccatccatt tatctgggaa gttggcggta agtacactta tcctcaagat
    33601 caacacttag tagaatacca tcatccacgt ggttttgatg attgttttga acaagactct
    33661 aacattcaat ttaaagcttt gctataatat aaaaatattc tttggaggtt atccgtatgt
    33721 tgcatgatac ggataatttt catataatag taaaatagaa tgtgtgattc aataatcacc
    33781 tcaaatagaa aggaaattct atgtcaaatc tatctgttaa tgcaattcgt tttctaggta
    33841 ttgacgccat taataaagcc aactcaggtc atccaggtgt ggttatggga gcggctccga
    33901 tggcttacag cctctttaca aaacaacttc atatcaatcc agctcaacca aactggatta
    33961 accgcgaccg ctttattctt tcagcaggtc atggttcaat gctcctttat gctcttcttc
    34021 acctttctgg ttttgaagat gtcagcatgg atgagattaa gagtttccgt caatggggtt
    34081 caaaaacacc aggtcaccca gaatttggtc atacggcagg gattgatgct acgacaggtc
    34141 ctctagggca agggatttca actgctactg gttttgccca agcagaacgt ttcttggcag
    34201 ccaaatataa ccgtgaaggc tacaatatct ttgaccacta tacttacgtt atctgtggag
    34261 acggagactt gatggaaggt gtctcaagcg aggcagcttc atacgcaggt ttgcaaaaac
    34321 ttgataagtt ggttgttctt tatgattcaa atgatatcaa cttggatggt gagacaaagg
    34381 attcctttac agaaagtgtt cgtgaccgtt acaatgccta cggttggcat actgccttgg
    34441 ttgaaaatgg aacagacttg gaagccatcc atgctgctat cgaaacagca aaagcttcag
    34501 gcaagccatc tttgattgaa gtgaagacgg ttattggata cggttctcca aacaaacaag
    34561 gaactaatgc tgtacacggc gcccctcttg gagcagatga aactgcatca actcgtcaag
    34621 ccctcggttg ggactacgaa ccatttgaaa ttccagaaca agtatatgct gatttcaaag
    34681 aacatgttgc agaccgtggc gcatcagctt atcaagcttg gactaaatta gttgcagatt
    34741 ataaagaagc tcatccagaa ctggctgcag aagtagaagc catcatcgac ggacgtgatc
    34801 cagtcgaagt gactccagca gacttcccag ctttagaaaa tggtttttct caagcaactc
    34861 gtaattcaag tcaagatgcc ttgaatgttg tggcagctaa attaccaacc ttcctaggtg
    34921 gatcagctga ccttgctcac tcaaacatga cttatatcaa gacggatgga cttcaagacg
    34981 ataccaatcg cttgaatcgt aacattcagt ttggtgttcg tgaatttgca atgggaacaa
    35041 tcttgaacgg gatggccctt catggtggac ttcgtgtata cggtggaact ttcttcgtct
    35101 tctctgacta tgtgaaggca gctgtccgct tgtcagcctt acaaggactt cctgtgactt
    35161 atgtctttac ccatgattca atcgcagttg gggaagatgg tccgactcac gaaccggttg
    35221 agcatttagc aggtcttcgt gctatgccaa atctaaatgt tttccgtcca gcagatgcgc
    35281 gtgaaacgca agcagcttgg taccttgcag tgacaagtga gaaaacacca actgcccttg
    35341 tcttgacacg tcaaaacttg actgttgaag atggaacaga cttcgacaag gttgctaaag
    35401 gtgcttatgt tgtatatgaa aatgcagccg actttgatac catcttgatt gcgacaggtt
    35461 cagaggttaa tcttgctgtc tcagctgcta aagaattggc tagtcaaggc gaaaaaatcc
    35521 gcgtagtcag catgccatct acagatgtct ttgataaaca agatgcagct tacaaggaag
    35581 agattcttcc aaatgcagtc cgccgtcgtg ttgcagtcga aatgggtgca agtcaaaact
    35641 ggtacaaata tgttggtctc gatggtgccg ttctaggtat taataccttc ggagcctctg
    35701 ccccagcacc aaaagtattg gcagaatatg gctttactgt agaaaatctt gtaaaaattg
    35761 ttcgaaactt gaaataatcc taaaaatcag ggcgtaagct ctggtttttc ttaccagaaa
    35821 agtaaggtac aatcttgtaa aagtagctga aatttgatat agtagtccta tgtaaaagac
    35881 aaaggagaaa acaatgaatc caaatattac ttttttaatc atgcttgtag gtatgatggc
    35941 cttgatgttc tttatgcaac gttctcaaaa gaaacaagct caaaagcgta tggaaagctt
    36001 aaataaacta caaaaaggct atgaagtgat tacaatcggt ggactttatg gaacagtcga
    36061 tgaagtagat acggagaagg gaacaatagt tcttgacgta gatggagttt acttgacttt
    36121 tgaactagct gctatcaaga cagtattacc gctgaaagaa acagcttcac tagaaggcgc
    36181 aattgaaaaa taagacggga tcacgaactc ccgtttttct ataaaagaaa ggaaatggga
    36241 tgaaaaaatt agtctttgtc tgtctgggaa atatttgccg tagccctatg gccgagtttg
    36301 ttatgaaatc aatgacagat aactacgaaa tccaaagtcg agcaacttcc tcttgggaac
    36361 atggcaatcc gattcataag gggactcagg gaatttttca agagtatgag attccttatg
    36421 acaagaacaa gacatcgctt cagattagta aggaagattt tgaagccttt gattatatta
    36481 tcggaatgga cgcttcaaat atttctgact tacgtcagat gtgtccagta gactgtcaag
    36541 ataagattta ctcattttca tctgaaagtg ttccagaccc ttggtataca ggagattttg
    36601 aagaaaccta tcgacgtgtt caagagggct gtcaagcttg gttagaacgt ttagaaaagg
    36661 agagttaagg tggaaaatct tacgaatttt tacgaaaagt atcgtgtcta tctgactcgt
    36721 ccacgattag agcttttggc agtagttacc attgttttct gtgctgtact cgtctttttt
    36781 ctaaatattc caggaaaagg tgtcttaaaa ctcgataatg gaacgattgt ttatgatggc
    36841 agtcttgtcc gtggtaaaat gaatggtcaa ggtaccatta ccttccaaaa tggagaccaa
    36901 tatacaggtg gcttcaacaa tggagccttc aacggaaaag gtacctttca atctaaagaa
    36961 ggctggacct acgaaggtga ttttgtaaat ggtcaggctg aaggaaaagg gaaactaaca
    37021 acagaacaag aagtcgttta tgaaggaact tttaaacaag gcgtttttca acaaaaataa
    37081 agcctcctta tcaaaggagg tattattaga atcgcaaggt aagcgcttac ctgcaaatcc
    37141 ctttctttcc aaatccctct tccaaccaag tttgtgaaat aaaaaatatt tgaaataaat
    37201 ttcacaaact tcaaagataa aacctgataa gaaaagaaaa tgagaaaagt ttcacaagag
    37261 tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca aagttgaaat aatgcgttat
    37321 aataaacttg tgaaaaaatt aacaaaggat atcgttcctt gaaagctatg gaggaaaata
    37381 tggctgataa aaaaactgtg acaccagagg aaaagaaact cgttgctgaa aaacacgtag
    37441 atgagttggt tcaaaaagct ctagttgccc ttgaagaaat gcgtaaattg gatcaagaac
    37501 aagttgacta catcgttgcc aaagcatcag tagcagcttt ggatgcccac ggagaattgg
    37561 ctttacatgc ctttgaagaa acaggacgtg gtgtatttga agataaagca actaagaact
    37621 tgtttgcttg tgaacacgtg gtaaacaaca tgcgtcacac taaaacagtt ggcgttatcg
    37681 aagaagatga tgtaacagga ttgaccctga ttgctgaacc agttggtgtt gtttgtggta
    37741 tcactccaac aacaaaccca acatcaacag cgatcttcaa atcattgatt tcattgaaga
    37801 cacgtaatcc aatcgtcttt gccttccatc catcagctca agaatcatca gttcatgcag
    37861 ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc tgaaaactgt gtacagtgga
    37921 tcactgaacc atctatggaa gcaactagtg cccttatgaa ccacgaaggt attgcaacaa
    37981 tccttgcaac aggtggtaat gccatggtta aagccgcata ctcatgtggt aaaccagctc
    38041 ttggggtagg tgccggaaac gttccagctt atgttgaaaa atcagcaaac attcgtcaag
    38101 cagcacacga tatcgtcatg tctaaatcat ttgataacgg tatggtctgt gcatctgaac
    38161 aagcagttat cattgataaa gaaatttacg atgaatttgt agcagagttc aaatcttacc
    38221 acacttactt tgtaaacaaa aaagaaaaag ctcttcttga agagttctgc ttcggcgtca
    38281 aagcaaacag caaaaactgt gctggtgcaa aattgaacgc tgacatcgtt ggtaaaccag
    38341 caacttggat tgcagaacaa gcaggattta cagttccaga aggaacaaac attcttgctg
    38401 cagaatgtaa agaagttggc gaaaatgagc cattgactcg tgaaaaattg tcaccagtta
    38461 ttgcagtttt gaaatctgaa agccgtgaag atggtattac taaggctcgt caaatggttg
    38521 aatttaacgg tcttggacac tcagcagcta tccacacagc tgacgaagaa ttgactaaag
    38581 aatttggtaa agctgttaaa gctattcgtg ttatctgtaa ctcaccttct acttttggtg
    38641 gtatcgggga cgtttacaat gccttcttgc catcattgac acttggatgt ggttcttacg
    38701 gacgcaactc agttggggat aacgttagtg ccattaacct cttgaatatc aaaaaagtcg
    38761 gaagacggag aaataacatg caatggatga aacttccttc aaaaacatac tttgaacgtg
    38821 attcaattca ataccttcaa aaatgtcgtg acgttgaacg tgtcatgatc gttactgacc
    38881 atgccatggt agagcttggt ttccttgatc gtatcatcga acaactggac cttcgtcgca
    38941 ataaggttgt ttaccaaatc tttgcggatg tagaaccgga tccagatatc acaactgtaa
    39001 accgtggtac tgagattatg cgtgccttca gaccagatac catcatcgca ctcggtggtg
    39061 ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta cgagcaacca gaagtggact
    39121 tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg tgccttcaag ttcccattgc
    39181 ttggtaagaa gactaaattc atcgcgattc caactacatc tggtacagga tctgaagtaa
    39241 caccatttgc cgttatctct gataaagcaa acaaccgtaa atacccaatc gctgactact
    39301 cattgacacc aactgtggca attgtagacc ctgctttggt attgacagtt ccaggatttg
    39361 ttgctgctga tactggtatg gacgtattga ctcacgcgac agaagcatac gtatcacaaa
    39421 tggctagtga ctacactgat ggtttagcac ttcaagctat taaattggtc tttgaaaatc
    39481 tcgaaagctc agttaagaat gcagacttcc actcacgtga gaaaatgcat aacgcttcaa
    39541 caatcgctgg tatggccttt gccaatgcct tcctaggtat ttctcactca atggcccata
    39601 agattggtgc gcaattccac acaatacacg gtcgtacaaa tgctatcttg cttccatacg
    39661 ttatccgtta caacggtaca cgtccagcta agacagcaac atggcctaag tacaactact
    39721 accgtgcaga tgaaaaatac caagatatcg cacgcatgct tggacttcca gcttctactc
    39781 cagaagaagg ggttgaatct tacgcaaaag ctgtctacga actcggtgaa cgtattggga
    39841 tccaaatgaa ttttagagac caaggaattg acgaaaaaga atggaaagaa cattctcgtg
    39901 aattagcctt cctggcttat gaagaccaat gttcaccagc taacccacgt cttccaatgg
    39961 tagaccatat gcaagaaatc atcgaagatg catactatgg ctacaaagaa agaccaggac
    40021 gccgtaaata attgtttatc agtctagaag caagacaaaa actcaatttg agggaaagat
    40081 ccagtaattt ttctatgata aaaggcatcc tatcaaggtt tttgaacacc tgataggatg
    40141 cctttttatg atattgaggc ctttttgccc tttttgaaaa actagaatag aaacaaaata
    40201 tataatagat tgaaactgga atagtacact tctgcttcta aaacattgtt agaattcgat
    40261 ttgactgtcc tgatcgattt gtcctattcc tatttca
//
LOCUS       DAVLZG010000010        39897 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLZG010000010 DAVLZG010000000
VERSION     DAVLZG010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.010"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            650..2803
                     /locus_tag="VYO72_000512"
     CDS             650..2803
                     /locus_tag="VYO72_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1706949.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNSLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2816..4165
                     /locus_tag="VYO72_000513"
     CDS             2816..4165
                     /locus_tag="VYO72_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1706950.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4335..5042
                     /locus_tag="VYO72_000514"
     CDS             4335..5042
                     /locus_tag="VYO72_000514"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1706951.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIVG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5244..8969
                     /locus_tag="VYO72_000515"
     CDS             5244..8969
                     /locus_tag="VYO72_000515"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1706952.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKTNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9062..10504
                     /locus_tag="VYO72_000516"
     CDS             9062..10504
                     /locus_tag="VYO72_000516"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1706953.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10541..11563
                     /locus_tag="VYO72_000517"
     CDS             10541..11563
                     /locus_tag="VYO72_000517"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1706954.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11560..12105
                     /gene="purN"
                     /locus_tag="VYO72_000518"
     CDS             11560..12105
                     /gene="purN"
                     /locus_tag="VYO72_000518"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1706955.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12189..12698
                     /locus_tag="VYO72_000519"
     CDS             12189..12698
                     /locus_tag="VYO72_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1706956.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12723..14270
                     /gene="purH"
                     /locus_tag="VYO72_000520"
     CDS             12723..14270
                     /gene="purH"
                     /locus_tag="VYO72_000520"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1706957.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14392..15654
                     /gene="purD"
                     /locus_tag="VYO72_000521"
     CDS             14392..15654
                     /gene="purD"
                     /locus_tag="VYO72_000521"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1706958.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKTFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15845..16336
                     /gene="purE"
                     /locus_tag="VYO72_000522"
     CDS             15845..16336
                     /gene="purE"
                     /locus_tag="VYO72_000522"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1706959.1"
                     /translation="MTKPIISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTP
                     DLMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSN
                     ELI"
     gene            16323..17414
                     /gene="purK"
                     /locus_tag="VYO72_000523"
     CDS             16323..17414
                     /gene="purK"
                     /locus_tag="VYO72_000523"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1706960.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17424..17651
                     /locus_tag="VYO72_000524"
     CDS             17424..17651
                     /locus_tag="VYO72_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1706961.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            17714..19012
                     /gene="purB"
                     /locus_tag="VYO72_000525"
     CDS             17714..19012
                     /gene="purB"
                     /locus_tag="VYO72_000525"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1706962.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19067..23005)
                     /gene="strH"
                     /locus_tag="VYO72_000526"
     CDS             complement(19067..23005)
                     /gene="strH"
                     /locus_tag="VYO72_000526"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1706963.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKADVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKIISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEDIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23318..24034)
                     /locus_tag="VYO72_000527"
     CDS             complement(23318..24034)
                     /locus_tag="VYO72_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1706964.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIEFISCDRDH"
     gene            24382..26169
                     /locus_tag="VYO72_000528"
     CDS             24382..26169
                     /locus_tag="VYO72_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1706965.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26166..26642
                     /locus_tag="VYO72_000529"
     CDS             26166..26642
                     /locus_tag="VYO72_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1706966.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26670..27575
                     /locus_tag="VYO72_000530"
     CDS             26670..27575
                     /locus_tag="VYO72_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1706967.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27562..28377
                     /locus_tag="VYO72_000531"
     CDS             27562..28377
                     /locus_tag="VYO72_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1706968.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28384..28788
                     /locus_tag="VYO72_000532"
     CDS             28384..28788
                     /locus_tag="VYO72_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1706969.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29087..30247
                     /locus_tag="VYO72_000533"
     CDS             29087..30247
                     /locus_tag="VYO72_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1706970.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEY"
     gene            30369..31406
                     /locus_tag="VYO72_000534"
     CDS             30369..31406
                     /locus_tag="VYO72_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1706971.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31613..32467
                     /locus_tag="VYO72_000535"
     CDS             31613..32467
                     /locus_tag="VYO72_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1706972.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            32617..32874
                     /locus_tag="VYO72_000536"
     CDS             32617..32874
                     /locus_tag="VYO72_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1706973.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33042..33170)
                     /locus_tag="VYO72_000537"
     CDS             complement(33042..33170)
                     /locus_tag="VYO72_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HEV1706974.1"
                     /translation="MDRTDEVSNHIYGKVKLMWFEEIFEEYKFLHNKTHITKVLMN"
     gene            complement(33204..33296)
                     /locus_tag="VYO72_000538"
                     /pseudo
     CDS             complement(33204..33296)
                     /locus_tag="VYO72_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33332..33628)
                     /locus_tag="VYO72_000539"
                     /pseudo
     CDS             complement(33332..33628)
                     /locus_tag="VYO72_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(33618..33779)
                     /locus_tag="VYO72_000540"
     CDS             complement(33618..33779)
                     /locus_tag="VYO72_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1706975.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            33849..34613
                     /locus_tag="VYO72_000541"
     CDS             33849..34613
                     /locus_tag="VYO72_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1706976.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35226..36605
                     /locus_tag="VYO72_000542"
     CDS             35226..36605
                     /locus_tag="VYO72_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1706977.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36619..37284
                     /locus_tag="VYO72_000543"
     CDS             36619..37284
                     /locus_tag="VYO72_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1706978.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37398..37493
                     /locus_tag="VYO72_000544"
                     /pseudo
     CDS             37398..37493
                     /locus_tag="VYO72_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            37639..38178
                     /locus_tag="VYO72_000545"
     CDS             37639..38178
                     /locus_tag="VYO72_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1706979.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            38245..38655
                     /locus_tag="VYO72_000546"
     CDS             38245..38655
                     /locus_tag="VYO72_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1706980.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            38771..>39897
                     /gene="pavB"
                     /locus_tag="VYO72_000547"
     CDS             38771..>39897
                     /gene="pavB"
                     /locus_tag="VYO72_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1706981.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETPGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLG"
BASE COUNT        10991 a         7780 c         9323 g        11803 t
ORIGIN      
        1 ttaattagaa aaaaattttt aaagtcttcg gagaagaaaa cagaaaaatc tgttaaaaaa
       61 taatcaaaac tataaatgat gaatctgaat caaaattatt ttgcgcatgt aaagaggagt
      121 cttatagtaa cgagtcaaaa aaggagtaac tatgaatcgt aatttagaac ggtgttatct
      181 attctgacta ggaatagatc ataccagagg tagcttagaa atagcagaga cattagaaat
      241 tgaagtaata aatgggatgt cgtaagtgtt actatcaatg atttatttgt ttcaagcttg
      301 cctagggtga cagtaaaaaa tcaatttcct ttcaatagca tatttttagt gggcaggact
      361 cttgttctgc ctattttttt atccaaaaag tgcagttggg agggagatag gctcatttgg
      421 gaaggaagtc cagtttttgt ttagtgattg gggtaagata gttgttatca gatgagttta
      481 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc ttgccgtata tatgtgactg
      541 acttcgtcag tcctatctac aacctcaaaa cagtgttttg agcagcctgc ggctagtttc
      601 ctagtttgct ctttgatttt cattgagtat tagggaaaag gagatgaata tgaaatttgg
      661 gaaacgtcac tatcgtccgc aagtggatca gatggactgc ggtgtagctt cattagccat
      721 ggtttttggc tactatggta gttattattt tttggctcac ttgcgagaat tggctaagac
      781 gaccatggat gggacgacgg ctttgggctt ggtcaaggtg gcagaggaga ttggttttga
      841 gacgcgagcc attaaggcgg atatgacgct ttttgacttg ccggatttga cttttccttt
      901 tgttgcccat gtgcttaagg aagggaaatt gctccactac tatgtggtga ctgggcagga
      961 taaggatagc attcatattg ccgatccaga tcccggggtg aagttgacta aactgccacg
     1021 tgagcgtttt gaggaagaat ggacaggagt gactcttttt atggcaccta gtccagacta
     1081 taagccttat aaggaacaaa aaaatggtct gctctctttt atccctatat tagtgaagca
     1141 gcgtggcttg attgccaata tcgttttggc aacactcttg gtaaccgtga ttaacattgt
     1201 gggttcttat tatctgcagt ctatcattga tacctatgtg ccagatcaga tgcgttcgac
     1261 actagggatt atttctattg ggctagtcat cgtctacatc ctccagcaaa tcttgtctta
     1321 cgctcaggag tatctcttgc ttgttttggg gcaacgcttg tcgattgacg tgattttgtc
     1381 ctatatcaag catgtttttc acctccctat gtccttcttt gcgacacgca ggacagggga
     1441 gatcgtgtct cgttttacag atgctaacag tatcatcgat gcgctggctt cgaccatcct
     1501 ttcgattttc ctagatgtgt caacggttgt cattatttcc cttgttctat tttcacaaaa
     1561 taccaatctc tttttcatga ctttattggc gcttcctatc tacacagtga ttatctttgc
     1621 ctttatgaag ccgtttgaaa agatgaatcg ggataccatg gaagccaatg cggttctgtt
     1681 ttcttctatc attgaggaca tcaacggtat tgagactatc aagtccttga ccagtgaaag
     1741 tcagcgttac caaaaaattg acaaggaatt tgtggattat ctgaagaaat cctttaccta
     1801 tagtcgagca gagagtcagc aaaaggctct gaaaaaggtt gcccatctct tgcttaatgt
     1861 cggcattctc tggatggggg ctgttctggt catggatggc aagatgagtt tggggcagtt
     1921 gattacctat aataccttgc tggtttactt taccaattct ttggaaaata tcatcaatct
     1981 gcaaaccaag cttcagacag cgcaggttgc caataaccgt ctaaatgaag tgtatctagt
     2041 agcttctgag tttgaggaga agaaaacagt tgaggatttg agcttgatga agggagatat
     2101 gaccttcaag caggttcatt acaagtatgg ctatggtcga gacgtcttgt cggatatcaa
     2161 tttaaccgtt ccccaagggt ctaaggtggc ttttgtgggg atttcagggt caggtaagac
     2221 gactttggcc aagatgatgg ttaattttta cgacccaagt caaggggaga ttagtctggg
     2281 tagtgtcaat ctcaatcaga ttgataaaaa agccctgcgc cagtacatca actatctgcc
     2341 tcaacagccc tatgtcttta acggaacgat tttggagaat cttcttttgg gagccaagga
     2401 ggggacgaca caggaagata tcttacgggc ggtcgaattg gcagagattc gagaggatat
     2461 cgagcgcatg ccactgaatt atcagacaga attgacttcg gatggggcag ggatttcagg
     2521 tggtcaacgt cagagaatcg ctttggcgcg tgctctcttg acagatgcgc cggtcttgat
     2581 tttggatgag gcgactagca gtttggatat tttgacagag aagcggattg tcgataatct
     2641 catagctttg gacaagacct tgattttcat tgctcaccgc ttgactattg ctgagcggac
     2701 agagaaggta gttgtcttgg atcagggcaa gattgtcgaa gaaggaaagc atgctgattt
     2761 gcttgcacag ggtggctttt acgcccattt ggtcaatagc tagaaagagg agaggatgaa
     2821 accagaattt ttagaaagtg cggagtttta taatcgtcgt taccataatt tttccagtag
     2881 tgtgattgta cccatggccc ttctgctcgt gtttttactt ggctttgcaa ctgttgcaga
     2941 gaaggagatg agtttgtcca ctagagctac tgtcgaaccc agtcgtatcc ttgcaaatat
     3001 ccagtcaact agcaacaatc gtattcttgt caatcatttg gaagaaaata agctggttaa
     3061 gaagggggat cttttggttc aataccaaga aggggcagag ggtgtccaag cggagtccta
     3121 tgccagtcag ttggacatgc taaaggatca aaaaaagcaa ttggagtatc tgcaaaagag
     3181 cctgcaagaa ggggagaacc actttccaga ggaggataag tttggctacc aagccacctt
     3241 tcgcgactac atcagtcaag caggcagtct tagggctagt acatcgcaac aaaatgagac
     3301 catcgcgtcc cagaatgcag cagctagcca aacccaatcc gaaatcggca acctcatcag
     3361 tcaaacagag gctaaaattc gcgattacca gacagctaag tcagctattg aaacaggtgc
     3421 ttccttggcc ggtcagaatc tagcctactc tctttaccag tcctacaagt ctcagggcga
     3481 ggaaaatccc caaactaagg ttcaggcagt tgcacaggtt gaagcacaga tttctcagtt
     3541 agaatctagt cttgctactt accgtgtcca gtatgcaggt tcaggtaccc agcaagccta
     3601 tgcgtcaggg ttaagcagtc aattggaatc ccttaaatcc caacacttgg caaaggttgg
     3661 tcaggaattg acccttctag cccagaaaat cttggaggca gagtcaggta agaaggtaca
     3721 gggaaatctt ttagacaagg ggaaaattac ggcgagtgag gatggggtgc ttcatcttaa
     3781 tcctgagacc agtgattcta gcatggttgc agaaggtgcc ctactagccc aactttatcc
     3841 atctttggaa agagaaggga aagccaaact cacagcctat ctaagttcaa aagatgtagc
     3901 aagaatcaag gtcggtgatt ctgttcgcta tactacgact catgatgccg ggaatcaatt
     3961 ttttctagat tctactatta caagtattga tgcgacagct actaagactg agaaagggaa
     4021 tttctttaaa atcgaggcgg agactaatct aacttcggag caggctgaaa aacttaggta
     4081 cggggtggaa ggccgtctac agatgattac gggcaagaaa agttatctac gttattattt
     4141 ggatcaattt ttgaacaaag agtaatgttc gtgtttttag agttaaataa tttttaaact
     4201 gtgagaaaga ttcttcttgc agttttttct ttacaatttt tgaaaaacat atgctattta
     4261 ttcggttaaa ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa
     4321 aggcgaactt taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata
     4381 caactgagga tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaacg
     4441 gtgtcaagaa ggagcagatt gtaggtaagg gagtcttgaa taatcagatc tcatctttta
     4501 tttttgagaa attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca
     4561 cggaacaact caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata
     4621 ctgctggttc cttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga
     4681 ttgtcgaatt ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg
     4741 tgaaattcct acagattgcg ggtgaccagc agattgccta cttgaaggaa gaaacgcgtc
     4801 gtatcaatga actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta
     4861 agctagagtt cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag
     4921 ataactgccg cttgtgggac gctgatggca accacatgga taaggatgtt ttccgtagag
     4981 gattgggaga actaaccgac gtttatgaga ttgtttggga aaagttgcag gaattgaaat
     5041 aatctgtttg caacggaaaa ccttcgtctc tcaactaaaa ggactcaggc tgaaaaggtc
     5101 ccccagacct tttcactctg tagagaacta ggtgaactaa cagatgttta cgaaattgtc
     5161 tgggaaaagt tgcagggttt aaaataacaa cctcaaggct gtttgggaat attgcaagag
     5221 ctgaaataaa ggaataagaa ttgatggata aacgtatttt tgttgaaaaa aaggctgatt
     5281 ttcaggtcaa gtcagagagt ttggttagag agctccagca caacttggga ctgtcaagct
     5341 tgaaaagtat tcgtattgtg caagtatatg atgtatttga cttggctgag gacttgtttg
     5401 cacctgcaga gaagcacatt ttctctgagc agggaaccga ccatgtttta gatgaagtat
     5461 ctgtgcaggc ggatcttgct aactatgctt tctttgccat tgaaagtctg ccagggcagt
     5521 ttgaccagcg tgcagcttcg tcacaggaag ccttgctttt gttgggaagt tcgagtgacg
     5581 tgacagtcaa cacagcccaa ctttacttgg tgaataaaga tattgatgcg actgagttgg
     5641 aagctgtcaa aaactacctg ctcaatccag ttgattctcg tttcaaggat atcacgacag
     5701 ggattgccaa gcaggagttt tcagagtcag acaagaccat tccaaaattg actttctttg
     5761 aaagctatac agcagaagac tttgctcgct acaaggccga gcaagggatg gccatggaag
     5821 tggatgattt gctctttatc caagactact ttaagtcaat cgggcgcgtg ccaactgaga
     5881 ctgaactcaa ggttttggac acttactggt ctgaccactg ccgtcatacg acttttgaga
     5941 cagagttgaa acacatcgac ttttcagctt ctaaatttca aaagcaattg cagtcaacct
     6001 atgacaagta tattgccatg cgcgaggagt taggtcggtc tgaaaaacca caaaccttga
     6061 tggatatggc gactattttc ggtcgttatg agcgtgctaa tggacgattg gatgatatgg
     6121 aagtctctga cgaaatcaat gcctgctcag ttgaaattga agtggatgtt gatggtgtca
     6181 aggaaccttg gctcctcatg tttaaaaatg aaacccacaa ccatccaaca gaaattgagc
     6241 catttggtgg agcggctacc tgtatcggtg gagctattcg tgatccgttg tcaggccgtt
     6301 cctatgttta ccaagccatg cgtatttcag gtgctggtga tattacagca ccgatttcgg
     6361 aaactcgtgc tgggaaattg ccacaacaag tcatttctaa aacagcagct catggttatt
     6421 cttcatatgg taaccagatt gggcttgcca caacctacgt tcgtgaatac ttccacccag
     6481 gctttgtagc taaacgtatg gaacttggtg ccgttgttgg tgcggctccc aagggcaatg
     6541 ttgtccgtga aaaacctgaa gcaggtgatg tgatcatcct tctcggaggc aaaacaggtc
     6601 gtgatggtgt cggtggtgcg acgggctctt ctaaggttca aacagttgag tctgtagaga
     6661 ctgctggtgc tgaggttcaa aaaggaaatg ccatcgaaga acgcaagatt cagcgcctct
     6721 tccgtaatgg caatgtcact cgtctgatca agaagtccaa tgactttggg gcaggcggcg
     6781 tctgtgtggc tatcggtgaa ttggcagacg gtcttgaaat cgacctcaac aaggtgcctc
     6841 ttaaatacca gggcttgaat ggtacagaaa ttgccatctc tgaatcacaa gaacggatgg
     6901 cggtcgtggt tcgtcctgaa gatgtggata ccttcgttgc cgaatgtaac aaagaaaata
     6961 ttgatgctgt tgtggtggcg acagtaactg aaaaaacaaa tcttgtcatg cactggaatg
     7021 gtgagacaat cgttgacttg gagcgtcgtt tccttgacac caatggtgtg cgcgtggttg
     7081 tcgatgccaa agttgtggac aaggatgtca aactcccaga agagcgtcaa acatctgctg
     7141 aaacactgga atcagatacc cttacggttc tatctgacct caaccatgca agtcaaaaag
     7201 gattacagac tatctttgac tgctctgttg gacgctcaac ggttaatcac ccacttggtg
     7261 gtcgttacca actcacacca actgaggcat ctgtgcagaa attgccagtt caacacggtg
     7321 tgactcatac tgcgtcggtc attgctcaag gtttcaaccc atatgtagct gaatggtctc
     7381 cataccacgg tgctgcttat gcggttatcg aagcaactgc tcgtttggtg gctgctggtg
     7441 ccaactggtc caaggctcgt ttctcttacc aagagtattt cgagcgtatg gataaacaag
     7501 cagagcgttt cggtcagcca gtagctgctc ttctaggttc tattgaagca caaattcagc
     7561 ttggcttgcc atctatcggt ggtaaggact ccatgtctgg tacctttgaa gaattgaccg
     7621 ttccgccaac cttggttgcc tttggggtga cgacggcaga tagccgtaag gtgctctctc
     7681 cagaatttaa agctgttggg gaaaatatct actacatccc aggtcaagcc ctctctgcag
     7741 agattgattt tgacttgatt aagaaaaatt ttactcagtt tgaagccatc caagctgacc
     7801 ataaagtgac atctgcatca gctgtcaaat acggtggtgt agttgaaagt ttggctcttg
     7861 ctacctttgg aaactatatt ggtgcagagg tgaccttgcc tgaacttaaa acagctttga
     7921 cagctcaatt aggcggcttt gtcttcacat ctcctgaaga aattgctgga gtagagaagg
     7981 ttggacaaac gaaagcagac tttacactga ctgtcaacgg tgtgaagcta gatggacaca
     8041 agcttgacag tgcatttcaa gggacattgg aagaagttta cccaacagaa tttacccaag
     8101 cgaaagaact agaagaagta ccagctgtgg catcagatgt tgtgattaaa gccaaagaaa
     8161 aggttgaaaa acctgtggtt tacatcccag tctttccagg aaccaactca gaatatgatt
     8221 cagctaaggc cttcgaaaaa gaaggtgcag aggtcaattt ggtgccattc gtgaccttga
     8281 atgaagaagc tattgtcaag tcagttgaaa ctatggttga caatatcgac aagactaata
     8341 ttctcttctt tgctggtgga ttctcggctg cggatgaacc agatggttca gctaagttta
     8401 tcgtcaatat cctgcttaat gaaaaagtgt gtgtggctat tgatagcttt atcgcccgtg
     8461 gtggtttgat tatcggtatt tgtaatggat tccaagcctt agtcaaatcg ggtctcctac
     8521 cctacggaaa ctttgaagct gctaacagta ctagcccaac cctcttctac aatgatgcca
     8581 accaacacgt ggccaagatg gtggaaactc gcattgccaa taccaactca ccatggttgg
     8641 ctggtgtgca agtgggcgat atccacgcta ttcctgtttc gcacggtgaa gggaagtttg
     8701 tcgtgacggc tgaggaattt gcagagctcc gtgacaatgg acaaattttc agccaatacg
     8761 ttgactttaa cggtaaacca agtatggatt ctaagtacaa tccgaatggt tctgtccatg
     8821 ccatcgaagg aattaccagc aagaatggtc aaatcatcgg taagatgggc cactcagaac
     8881 gttatgagga tggtcttttc caaaatatcc caggcaataa agaccaacac ctgttcgcat
     8941 cagcggttaa acatttcact ggaaaataag acttacagat tttctaatag atagtatcag
     9001 taatgtaaaa gtcatgtaaa tctagctctt gatgattaca aatgaaaatt aggtataaaa
     9061 aatgacatac gaagtaaaat ctcttaatga agaatgtggt gttttcggta tttggggaca
     9121 tccagatgct gctaagttga cctattttgg actccacagt cttcaacacc gtggtcagga
     9181 gggggcagga atcctctcca atgatcaagg acaactgaag cgccatcgtg acatggggct
     9241 tttatcagaa gttttcagaa atccagccaa tttggataaa ttgacaggag ctggtgcgat
     9301 tgggcatgtg cgttatgcga ctgctggcga agcttctgtt gataacatcc aacccttcct
     9361 cttccgtttt cacgatatgc agtttggttt ggctcataat ggaaatctga ccaatgcagc
     9421 ctctctcaag aaagaactgg aacaaagagg agcaattttc agcgcgactt cggactctga
     9481 aatcttggct cacctcattc gtcgcagtca taatcctagc ctgatgggca aaatcaagga
     9541 agcgctcagc cttgtcaaag gtggttttgc ctatatcttg ctgtttgagg acaagttgat
     9601 tgcggctctt gaccctaatg gctttcgtcc gctttctatc gggaaaatgg ccaacggagc
     9661 ggtggttgtt tcctctgaaa cctgtgcttt tgaggtcatt ggtgccgagt ggattcgtga
     9721 tttgaagcca ggtgagattg tgatcattga tgacgagggc attcagtatg acagctatac
     9781 agatgatacc cagttggcga tttgttctat ggagtatatc tactttgccc gccctgattc
     9841 taatatccac ggtgtcaatg tccatacggc acgtaagaga atgggagcgc aattggcgcg
     9901 agaatttaag catgaggcag atattgtagt tggtgtgccc aattcttccc taagcgcggc
     9961 tatgggattt gcggaagaat caggcttacc aaatgaaatg ggtctgatca aaaaccaata
    10021 cacccagcga acttttatcc aaccgactca agaattgcgg gagcaaggag tgcggatgaa
    10081 actgtctgct gtttcgggtg ttgtcaaagg caaacgtgtg gttatggtgg atgattccat
    10141 tgtacgtgga acaacctctc gtcgtatcgt tcagctcttg aaagaagcgg gtgcgactga
    10201 ggttcacgtt gccattggaa gtcctgcact agcgtatcca tgtttctacg ggattgatat
    10261 ccagacccgt caggagctga ttgcagccaa tcatacggtc gaagaaactc gccaaatcat
    10321 tggtgcggac agtctgactt atctttcaat tgatagcttg attgagtcga ttggtatcga
    10381 aacagatgcg ccgaacggtg gtctctgtgt cgcttacttt gacggtgact acccaacgcc
    10441 tctctatgac tacgaagaag actatcgtag aagtttggaa gaaaagacca gtttttacaa
    10501 gtaggcgaca gattctccat taaagaaaag gaaaaaacaa atgacaaata aaaatgcata
    10561 tgcccagtcg ggtgtggatg ttgaagcggg ttatgaagtt gttgaacgga ttaaaaagca
    10621 cgtggcccgt acggagcgtg caggtgtcat gggagctctt ggtggctttg gtggtatgtt
    10681 tgacctttcc aagactgggg ttaaagaacc cgtcttgatt tcagggactg acggtgtcgg
    10741 aaccaagctc atgttggcta tcaagtacga caagcacgat accatcgggc aggactgtgt
    10801 ggccatgtgt gtcaacgaca tcattgctgc aggtgcggaa cccctctatt ttctcgacta
    10861 cgtagcgaca gggaagaatg aaccagctaa gctagaacaa gtggttgctg gtgtggcaga
    10921 aggttgtgtg caggctggtg ctgccctcat cggtggggaa acggctgaaa tgccgggcat
    10981 gtacggcgaa gacgactatg acttggctgg ttttgcggtc ggtgtggctg aaaaatctca
    11041 aatcattgac ggttcaaagg tggtagaggg agatgttctt ctcggacttg cttcaagtgg
    11101 gattcactca aatggttact ctttggttcg tcgtgtcttt gcggattaca caggtgagga
    11161 agtcctacca gaattggaag gcaagaaact taaggaagtt ctacttgagc cgactcgtat
    11221 ctatgtcaag gctgtcttgc cgctcatcaa agaagagttg gtcaacggca ttgcccacat
    11281 cacaggtggt ggctttatcg aaaatgtccc tcgtatgttt gcagatgacc tagctgctga
    11341 aattgatgaa agcaaagttc cagtgcttcc aattttcaaa gcccttgaaa aatatggtca
    11401 gattaaacac gaagaaatgt ttgaaatctt caatatgggt gtgggactta tgttggcggt
    11461 cagccctgaa aatgtagagc gtgtaaaaga attgttggat gaagcagtct atgaaattgg
    11521 tcgcatcgtc aagaaagaaa acgaaagtgt cattatcaaa tgaaaaaaat agcggttttt
    11581 gcctctggta atggctcaaa ttttcaggtg attgccgaag aatttccagt ggagtttgtc
    11641 ttttcagacc atcgtgatgc ctatgtgctt gagcgtgcaa agcagctcgg cgttctgtcc
    11701 tatgcttttg aactcaagga gtttgagagc aaggcagact acgaagcagc ccttgtcgaa
    11761 ctcttggaag aacaccagat tgacttggtt tgcctagcag gctacatgaa aatcgttgga
    11821 ccaaccttat tgtcggctta tgaaggtcgg attgtcaaca ttcatccagc ctacttgcca
    11881 gaatttccag gagctcatgg gattgaggat gcttggaatg ctggcgtggg tcagtctggt
    11941 gtgaccattc actgggtgga ttcgggtgtg gatacaggcc aggtcatcaa acaggttcgt
    12001 gtgccacgac tagctgatga taccattgac agatttgaag ctcgcatcca tgaagcagag
    12061 tacaggctgt atccggaagt agtgaaggct ctatttacag attgactttt tgatgattca
    12121 tatgatatct ttgattttaa attggagtca gtgtttgttg aagacggctt caaacggagg
    12181 tatttgtaat attagaatct aaaaaaacaa ctcgatatgt attttatgtc tatctgatgt
    12241 tattaacttg gggaatctta tttaagtttg aaacaaatcc tgaatttata gcatttttct
    12301 tagctccaag gtatatcaat tggattccat tttcagaacc actaatagtc gatggaaaaa
    12361 ttgtttttgc tgaaatgtta tttaatctga tttcctttat tccattaggt gtttgtttcc
    12421 ctttgataaa aactaattta tctagtttaa gaatagtcgg gacaggtttc ttgattagtt
    12481 tattgtttga gtgcttacag tatattttag caataggtat aacagatata acggatttga
    12541 ctttaaatac gctaggtgtc tgtgtaggct tactgattta tcaaattttt ataagagtgt
    12601 tcaaatcaca gactagaaaa tggatcaata tcttaggtat gcttagcctt ggttttgctt
    12661 atcttgtttt actgttactg catttaattg gtgtttaact aatgattaaa aaggagaata
    12721 taatgactaa acgcgtctta atcagcgtct cagacaaagc gggcattgtt gaatttgccc
    12781 aagaactcaa aaaacttggt tgggagatta tctcgacagg tggaactaag gttgcccttg
    12841 ataatgctgg ggtggatacc attgctatcg atgatgtgac tggtttccca gaaatgatgg
    12901 acggtcgtgt gaagaccctc cacccaaata tccacggggg gcttctcgct cgtcgtgact
    12961 tggatagcca cttggaagcg gctaaggaca acaagattga gctcattgac cttgtggtgg
    13021 tcaaccttta cccatttaag gaaactatcc ttaaaccaga tgcgacttat gctgatgcag
    13081 ttgaaaatat cgatattggt gggccatcta tgcttcgttc agcagcgaaa aatcatgcca
    13141 gtgttacagt tgtggtagat cctgctgact acgctgtggt tttggacgaa ttggcagcaa
    13201 acggcgaaac ctcttatgaa actcgccaac gtttagcagc caaagtattt cgtcacacag
    13261 cggcttatga cgccttgatt gcagaatact tcacagctca agtgggtgaa agcaagcctg
    13321 aaaaactcac tttgacttat gacctcaagc aaccaatgcg ttacggtgag aatcctcaac
    13381 aagacgcgga cttttaccag aaagctttgc ctacagacta ctccattgct tcagccaaac
    13441 agctcaacgg gaaagaattg tcatttaata atatccgtga tgcagatgct gctatccgta
    13501 tcatccgtga cttcaaagat agtccaaccg ttgtggctct caaacacatg aatccatgtg
    13561 gaattggtca agctgatgac atcgagactg cttgggacta cgcttatgag tctgacccag
    13621 tgtctatctt tggtgggatt gtcgtcctca accgtgaggt ggatgctgcg acagctgaga
    13681 agatgcacgg cgttttcctc gaaatcatca ttgcaccaag ctatacggat gaagcgctag
    13741 ccattttgat caataaaaag aaaaacttgc gtatccttgc cttgccattt aatgctcaag
    13801 aggctagcga agtggaagca gaatacacag gtgtagtcgg tggacttctc gtgcaaaatc
    13861 aagacgtggt caaggaaagc ccagctgact ggcaagtggt gaccaaacgt cagccaaccg
    13921 agacagaagc gactgctctt gagttcgctt ggaaggctat caagtacgtc aaatcaaatg
    13981 gtattatcgt gaccaacgac cacatgacac ttggtgttgg tccaggtcaa accaaccgtg
    14041 tggcttctgt tcgccttgcc attgaccaag ccaaagatcg tctggacggg gcggtccttg
    14101 cttcagatgc cttcttccca tttgcggata acgtggaaga aatcgctaaa gcaggaatta
    14161 aggccatcat ccagcccggt ggctctgtcc gtgaccaaga atccatcgaa gcagcggata
    14221 aatacggctt gactatggtc tttacaggtg tgagacattt tagacattaa gaagataaaa
    14281 gggaagaaaa cagtttcttt ccttttttgg cttaaaatgc taactgaaac aagattaaaa
    14341 cgaacttttt tgatataata ttggtaaata attcgcaaaa gaggttgagg aatgaaactg
    14401 cttgttgtcg gttcgggtgg tcgtgagcat gcgattgcta aaaagttact tgaatcaaaa
    14461 gatgtggaaa aagtctttgt agctcctggg aatgatggga tgactctgga tggtttggaa
    14521 ttggtaaata tctctatttc cgaacattct aaattgattg acttcgcaaa gaccaatgat
    14581 gttgcttgga cctttatcgg tccagatgat gcccttgctg ctggtatcgt ggatgatttt
    14641 aaccaagctg ggcttaagac ctttggtccg actagggctg cagcggagct ggagtggtcc
    14701 aaggattttg ccaaggaaat catggtcaaa tatggtgttt cgacagcagc ctatggcaca
    14761 ttttcagatt tcgaggaagc aaaggcttat atcgaaaagc atggtgcgcc tatcgtagtc
    14821 aaggcggatg gcttggcgct tgggaagggt gtcgtcgttg ctgagacggt tgagcaagcg
    14881 gtcgaagccg ctcatgagat gcttttggac aataaatttg gtgactcagg tgcgcgcgtg
    14941 gttattgagg aattccttga aggagaggaa ttttcactct ttgcctttgt caatggtgat
    15001 aagttctaca tcatgccaac ggctcaggac cacaaacgtg cctacgatgg cgacaaaggg
    15061 cctaacacgg gtggtatggg tgcctatgcg ccagttccac acttaccaca gagtgtagtt
    15121 gatacagcgg ttgacaccat tgtcaagcca gttctagaag ggatgattaa agaaggtcgc
    15181 ccttatctgg gagttcttta cgcagggctt atcctgacag ctgatggacc gaaagtcatc
    15241 gagttcaacg ctcggttcgg agatccagaa actcagatta tcttgcctcg cttaacctct
    15301 gactttgctc aaaatatcac agatatcctg gatagcaagg agccaaatat catgtggacg
    15361 gacaagggtg tgactctggg tgtggttgtc gcatccaagg gctacccgct agactatgaa
    15421 aggggcgttg agttgccagc caagacagaa ggcgatgtca tcacctacta tgcaggggct
    15481 aagtttgcgg aaaatagcag agcactgctc tcaaacggcg gacgagttta tatgctcgtt
    15541 accacagcag ataccgtcaa agaagcccaa gccagcatct accaagaact atcccaacaa
    15601 aaaatagaag gactcttcta ccgaacagat atcggaagca aggcaattaa gtaaagatat
    15661 aagaataacg cgccgtagtc gccaaacacg ataatggtcg tcgtggtgaa aagaccagaa
    15721 cagtgaatgt tctggtcagg gggaaatttg gagaccgtag gctcaaagtt taggaatgaa
    15781 accgaaggtt tgcttccgcc tccatcacct aagatcatta ttaaaaaaga agaaaaggaa
    15841 aattatgacc aaaccaatta tttccatcat catgggctca aaatccgatt gggcaaccat
    15901 gcaaaaaaca gcagaagtct tagaccgctt cggtgtagcc tacgaaaaga aagttgtttc
    15961 tgcccaccgt acacctgatc tcatgttcaa acatgcagaa gaagcatata gccgtggtat
    16021 taaggtcatc atcgcaggtg ctggaggcgc agcccacttg ccaggaatgg tagctgccaa
    16081 aacaaccctt cctgtcatag gggtacctgt caagtctcgt gctcttagtg gagtggattc
    16141 actctattct atcgttcaga tgccgggtgg ggtgcctgtt gcgaccatgg ctatcggtga
    16201 agctggagcg actaacgcag ctctctttgc cctccgtctc ctctctgtag aagataagtc
    16261 cattgcggat gcacttgcca actttgctga agaacaagga aaaatcgcag aggagtcgtc
    16321 aaatgagctc atctaaaaca atcggaatta tcggtggcgg tcaactgggt cagatgatgg
    16381 ccatttctgc tatctacatg ggccacaagg ttatcgcgct ggatcctgcg gcggattgcc
    16441 cggtctctcg tgtggcggaa atcattgtgg caccttataa cgatgtagac gccctccgtc
    16501 agttggcaga ccgttgcgat gtcctcactt acgagtttga aaatgtcgac gctgacggtt
    16561 tggatgccgt tatcaaggat ggacaactcc ctcaagggac agacctgctc cgcatttcgc
    16621 aaaatcgtat ttttgaaaag gactttttgt caaacaaggc tcaagtcact gtggcaccct
    16681 acaaggtcgt gacttctagc ctagacttgg cagatatcga cttgtcgaaa aactatgtcc
    16741 tcaagactgc gactggtggc tacgatggtc atggacaaaa ggttattcgt tcagaagtag
    16801 acttggaagc agcctatgcg ctagcagaat cagcagactg cgtcttggaa gaatttgtca
    16861 actttgccct tgagatttct gtcatcgtgt caggaaatgg caaggaggtg acgtttttcc
    16921 cagttcagga aaatatccac cgcaacaata tcctgtctaa gaccatcgta ccagcccgca
    16981 tttctgaaag tctagtagac aaggctaaag ctatggcagt gcgaatcgca gaacaactca
    17041 acttgtctgg aactctctgt gtggaaatgt ttgcgactga tgatgacgtt attgtcaatg
    17101 aaatcgcccc acgaccacat aactctgggc actattctat tgaagcctgt gatttctctc
    17161 agtttgacac ccatattctc ggtgttctcg gagcaccatt accagtcatc aaactccatg
    17221 cgccagccgt tatgctcaat gtcctaggtc aacacgtcga ggctgctgaa aagtatgtcg
    17281 cagaaaatcc aagcgcccac ctccacatgt atggtaaaat agaagcaaag cataatcgta
    17341 agatgggaca tgtgaccttg tttagtgatg taccggatag tgtggatgag cttggggaag
    17401 ggattgattt ttaggacaag tctatgatac aaattatcgt taatacattt attgaaaagg
    17461 ataagactgg agcagttgtt gaagtgttgt atgccagtgc tgaccaagat aaggtacaag
    17521 ctaaatatga agaactagct gcacaatacc ccgaaaatta tttagctatc tatgatgtac
    17581 cgctggatac ggatttgaat acactagatc attacccgtc tgtgtttatt ggaaaagagg
    17641 agtttgagta gaaatcttgg tttacctaga tagcttattc ccaacagctt aagaagaaag
    17701 gaaaaattaa cacatgatca accgttactc tcgccctgag atggcgaata tttggagtga
    17761 agaaaataaa taccgtgctt ggcttgaggt ggaaatcctc tctgacgagg catgggctga
    17821 gttgggggaa atccctaagg aagatgtggc tttgattcgc aagaaggcgg actttgacat
    17881 cgaccgtatt ttggaaattg agcaggagac gcgccacgat gtggtggctt tcacgcgtgc
    17941 ggtttctgag actcttggtg aagagcgcaa gtgggttcac tatgggttaa cttctaccga
    18001 cgtggtggat actgcttatg gttacctcta caagcaggcc aacgacatca tccgtcgtga
    18061 ccttgaaaac ttcactaata tcatcgctga caaggccaag gagcacaagt tcaccatcat
    18121 gatggggcgt actcatggtg tgcacgctga gccgacaacc tttggtctta aattggcaac
    18181 ttggtacagc gaaatgaaac gcaatatcga gcgcttcgag catgcggctg ctggtgtaga
    18241 agctggtaag atttctggtg cggttgggaa ctttgccaat atcccaccat ttgtagagga
    18301 gtatgtctgc gataaacttg gcatccgtgc ccaagaaatc tctacacaag tccttcctcg
    18361 tgaccttcac gctgagtact ttgcggttct tgccagcatt gcgacttcaa tcgaacgtat
    18421 ggcgactgag attcgtggtc tacaaaaatc tgagcaacgc gaagtagaag agttctttgc
    18481 taaagggcaa aaagggtctt cagcaatgcc tcacaaacgc aacccaatcg gttctgaaaa
    18541 tatgactggt ctggcgcgtg tcattcgtgg tcacatgatt acggcttatg aaaacgtcgc
    18601 tctctggcac gaacgcgata tttctcactc atcagctgag cgtatcatca caccagatac
    18661 gaccattttg attgactaca tgctcaaccg ttttggaaat atcgtcaaga acttgacagt
    18721 cttcccagaa aatatgatcc gaaacatgaa ctcgactttt ggtcttatct ttagccaacg
    18781 ggctatgttg acattgattg aaaaaggcat gacccgtgag caagcctatg acttggtgca
    18841 accaaaaaca gcctactctt gggacaacca agtagacttt aaaccacttc ttgaggcaga
    18901 ttcagaagta acatcacgtc tcacacaaga agaaatcgat gaaatcttca acccagttta
    18961 ttacaccaaa cgagtggatg atatctttga acgtcttgga ctaggtgatt aattaaaaaa
    19021 taaacagcga gcttcaatct cgctgtttat tttttatcga aaagacttag tcttcttttc
    19081 ttttagtgag tccataggct gctagtgtgg acatgagtcc tgcgactact agtcctgcag
    19141 aatcgtgagt tcctgtttca ggaagttttt tctctgttac cacaggagct ggatcttgag
    19201 gaagaacttt gctttcctca gcaggagcag ttgatggagc tggttggctt gggatttcta
    19261 gttttggttt ttcttcagca atagcggctt gtccgttttc atcgcctaca tgtgttacca
    19321 tagttccgac ttcgactatt tgagtaacgg cttcctgtgc tacgacacta tttacaagtg
    19381 ttttcacttc cttaccatcg gcagaagtgc tcacagagta gaagttgcta cgatgtccat
    19441 tgacgccctt agtaatgact tgtgtttttc ctttgagtaa gagtggattt tcacgagtca
    19501 ctgtggtaaa tggaatgtct tcttcttgga tatccagtct aggttttacc tcagtagttg
    19561 gtgcaagacc actttcatca cccttgtgag ttacaggagc gccaacttca accacttggt
    19621 ttataacttc tttggttacc tggctatcaa ggactgtttc tgttgttttt ccattttcag
    19681 tgagtacaga gatgtaatga gttcgttcac ctttgactcc tgctgtgata atattttcct
    19741 gaccggctgg gaggttagga ttttctttct tgataacttc aaatggaatt tcttcagttc
    19801 ttgtgatgag ttctggtctg gtttcaacat tggcagccac ttcattttca tctaggcttc
    19861 ctgaatgagt tacagctggt ttgaggcctt gaagagcggc ttttaggttg gctacaagtg
    19921 tgtcaagctc agcttgttta ttacggttga ggttgtaatt tagagctgtt ttagctgcgt
    19981 caagggcctc aagactttct ttactatatc cttctaagtt tgtaggaatt ttagctaatt
    20041 cttcgcggag agcattataa ttagcacgga agtagtcttt gttgtggtct gcaaaggcag
    20101 tcatgagttc aaagatttcc tcttccttgt attcagcgct tggtctatct gcccagattg
    20161 aaagcatact tccgactgtt ggaagatcta cttcaggata tttggtagaa gctagttgat
    20221 tgaatggtgt ttttccagta ttctcaatag ctttcttgag gaaaccacca ccatcttctg
    20281 gtttttgacc aagaatgtag taccagtcac cgttggtatt caagaattta tagcctttgc
    20341 ttgctaggta ttgaggtgat gcgaggttat atccccacca gcctttagac cagtaagaaa
    20401 tcaagacatc tttgtcaaac tgaacatcgt ccttgtcttc atagtagaag ccatcgttga
    20461 aggccattgg ttgaagccct ctttctttgg ccatagctgc gagggtgttg gcatattcgg
    20521 caaatttgcc atagagttga taccacttga ggtagtacca gccttgggca ctagtcgcat
    20581 cgttggcgta ttcgtcagta ccaaagttga aaatctttgt tttacctgca aagaagtcca
    20641 tgtatttacc gatgagggct tttacaaagt tcatcgcttc ttcgtttttc aagtccatag
    20701 ttgtttttga aactttatca aagtgggctt gaggattttt aatacctaat ttttccatgg
    20761 caaccagcat agcatccatg tgacctggac tgttaatagc tgggatgaga ccgatgtcct
    20821 tagatttagc gtattcaatt agctctgtca cttctgcctg tgttagtgca gtaccgtttg
    20881 gatcgtcgta gtaagcttta gttccttcga taatagcttt tttaacgtca tcactagcat
    20941 aggtttttcc gttggcagta atggtcatat catcgagtag aaagcgaagt ccgtcatttc
    21001 ctagaaggag atggacatca gaatatccga gctcactggc cttgtctacg atgcgtttga
    21061 gctggttcag agtaaagtat ttgcgtccag catcgattga gattatcttg tttttggcaa
    21121 gtttttcaac ctcacgttta gcttcttctt ctttttgagc ttcaggcgtg agggtcaagt
    21181 tgttgacagt ttcttgaagt ttagcaatgg cttgatcaat cgtatcttgt tgggcacggc
    21241 taaggttgct atcgagagag cgaatagctt tttcagcttc ttttacggcc gtgacgcttt
    21301 ctgcagtata acggttcagg tcttttggta cctcgttaag tgcttgctct gcagattcat
    21361 aatcagctgc gaagtattca gcgttggcat ttgcaaaatg acgcatgagt ttgaagaggc
    21421 gtgatggtga ataacgtgca gatggagtgt cagcccaagc agctaccata ccaccgatga
    21481 ttgggatatc agctccttct gtttttggta cagaagtgat tggtgtgttt ttaataccat
    21541 tgagcccctg atcgagattg taccagcctt ggccatcagc gtttcgtcca agaacgtagt
    21601 accaagcatc attggtatta aggatttggt gacctttttc agctagtagt ttagaagaag
    21661 cgacatcgta gcctccccaa ccaccagtcc acatagaaac gatgatgtct ttgtcaaaac
    21721 taccaaagct tgtgtcgcta ttgtagtaga taccgtcgtt aaaggccatt ggtttgagac
    21781 cgtgcgattt tacaatacga gcgaggtcat tggcgtaggc aataaatttt tcatagcctt
    21841 ttacagggta gccttcgttt ggatagtatt tatcagcttg aagcacactc caacctttag
    21901 catctgtcgc atcattggca tattcatcaa gtccgatgtt gaagatttca gtctttttcg
    21961 cgaaataagc agcatacttg tcgataaggg cttttgtaaa agcgacagct tgttcgttgt
    22021 caagatcgac agtacgggct gattccttcc caaaatagct aaagttaggg ttttggattc
    22081 ccaattcttt catggcattg agaatcgcat ccatgtgccc aggactattt actgtcggaa
    22141 tgagaccgat acctttatct ttggcatagt taatcagatc tgtcatttga ctttctgtta
    22201 agtgattgcc gtttggatcg tcgtaataat catttgtacc tttttcaatg gcgcgtttga
    22261 catcgtcact ggcataggtc ttgccgttag ctgtgatgct catatcgtcc aacatgaaac
    22321 ggagtccatc atttccgact aataggtgta aatcagtgta gccataatgt ttcgctttat
    22381 cgatgatttc cttgagctgt tctggtgaga aatatttacg tccagcatca atagaaacaa
    22441 ttttcttttt cgctagtttt tcatttacag ttgcagcacg ttcctttcct gcctctgttt
    22501 ccggtttgtc agcctctgct ttcgcttcat cttttttagc tggtttatcc ttgtcagtct
    22561 tgtctgtatt tgactcttta gaatcaacct ctttcgcttc ttccttttta gggctagctt
    22621 cttctgcctt tttattagca gtttcttttt cagcagaagt tggagttacc acgtctgctt
    22681 tatcactagg agttgaacta acttcctctt gtggtttttc ttctgttttt ggaagactag
    22741 ctaccttatc agtagctgga gtttctgttt ctacagtttt tggagcttct ggttgaagct
    22801 ctgctttagg tgtttcctca gtccgatttt cggatgattg aggggaatca gaaaccgtat
    22861 ggatggtcgg ttggttttct gtagtagtag gagtaactcc atcggctgca acagtctgtg
    22921 cttggaaggc aaatccaatt agaacagaag ctgctcctac agcgtattta cgaatagaaa
    22981 aacgctgttg tttttcatgt ttcattgcaa aacctcctga ttgcattgtt atattgatag
    23041 cgattatata aatcaacgcc tttattttat ttcttatatt aacgagagtc aagaggagat
    23101 gacaaaaaac tataataagt ataaaaaaat ataaaattta aacttaagat ttcagattgg
    23161 tcgaaaatac atatatatat ctagtataat ttttggttct atttctataa aatattccac
    23221 aaattataga atcttccaaa aataggtaag cgctaccttt ttggtgtggt ataataagca
    23281 tagaaaaagc ccgagcgatt aggctcaggc tttcttctta gtgatcacgg tcacatgaga
    23341 tgaattcaat cttgtagtaa tcagatcgtt tgtaagtttc actgtattct aaaacttggc
    23401 cagttgattc gagtttggtg attttagttt gtaggacagt agggaattgt tcatcgactc
    23461 cgaggactga agccgcatgt tctggagttg gaaagactat ttcgttgatt tcttcaaagt
    23521 gttcatcatt catgtgaatg tggtagtcta acttgaaacg attatagata gaactatagt
    23581 attcaaggtt tggataattt gcgttgatat attgttctgg gatgtaggat gtatggtaga
    23641 tataaacgac accgtttgat tcgcggatac gttcaatctt gtagtagaat tgatcgccgc
    23701 gtagacccaa tttttccaag taaacaagct tgtttccgcg ttcaattgaa agaacagtta
    23761 ccttatcatc tttagcattg aagagttcaa tatctgaaaa ctctacaagc ttgtgtttgc
    23821 gtgcacgtga aacgaaggtt ccttttcctt gttggcggac aatatagcca tctttggcaa
    23881 ggtcgtttaa ggcgcgaaca actgtgatag agctgacatc gtacattgaa atgagttctg
    23941 cttcagtgta aaatttatct ccactgctaa actgcccaga gatgatttta ttttttaatt
    24001 cgtcttttat gtattgatat ttgggaattg ccatattttt acctctattt tccttctcca
    24061 tagaaaattt taccataaaa gcgaaaaaaa tagtagtctt ttgaataaaa aattagaata
    24121 atagtttgaa aaattaagcg atatagggat tgctcatatt ttatcaatgt attctataca
    24181 aaattatttt aggtcctata ttccgaattt aaagagcgtt tgaaatgggt ctaaaaatgt
    24241 ttgaaactaa ttgaatgtgt gtataatagt aaaaatgcag taaatatccc gacaatttct
    24301 attgacaatt caaacagatt ggtttataat taatataaca acaaatgaaa gcgcaaactt
    24361 tcgcggtcgg aaggtagttt tatgacacga tttgagatac gagatgattt ctatctcgat
    24421 ggaaaatcat ttaagatttt atctggtgcc attcattatt ttagggttcc tccagaggat
    24481 tggtatcatt cgctctataa cttgaaggct cttggtttta atacggtaga gacttatatt
    24541 gcttggaatt tacacgagcc tcgtgaaggt gagtttcatt ttgacggtga tctggattta
    24601 gagaaatttc tccaaatagc gcaggatttg ggtctctacg caattgtgcg tccgtctcca
    24661 tttatctgtg cggaatggga attcggtggc ttaccagctt ggctcttgac caagaacatg
    24721 cgaattcgct catccgaccc agcatatatc gaggcagttg gtcgctacta tgatcagtta
    24781 ttgccaagac tggtgcctcg tttgttggac aatggtggca atattctcat gatgcaggtt
    24841 gaaaatgagt atggttctta cggagaagat aaggcttacc tgagagcgat tcgacagcta
    24901 atggaagagc gtggcgtaac ctgtcctctc tttacatcag atggtccatg gcgagctact
    24961 ctgaaagctg gaaccttaat tgaagaggac ctctttgtaa caggaaactt tggttctaag
    25021 gcaccttaca acttttcgca gatgcaggaa ttctttgatg aacatggtaa gaaatggcca
    25081 ctcatgtgta tggagttctg ggatggttgg tttaatcgct ggaaagaacc gattatcaca
    25141 cgggatccta aggaattggc agatgcagtt cgagaggttt tggaacaagg ctctatcaat
    25201 ctttacatgt tccacggtgg tacaaacttt ggtttcatga atggttgctc ggctcgagga
    25261 actttggacc tgccacaagt tacgtcttat gattacgatg cccttctgga tgaagaagga
    25321 aatccaactg ctaaatatct tgcagtcaag aagatgatgg caacacattt ttcagagtat
    25381 ccgcagttgg aaccactcta caaagagagt atggagttgg atgctattcc actagttgaa
    25441 aaagtttctt tgtttgaaac cttagatagc ttgtcaagtc ctgtagaaag tctctatcct
    25501 caaaagatgg aggagctggg acaaagttat ggctacctac tttatcgaac agaaacaaac
    25561 tgggatgcag aagaagaaag acttcgtatc attgatggtc gagatagggc ccagctgtat
    25621 gtcgatggtc agtgggttaa aactcaatat cagacagaga ttggggaaga tattttttat
    25681 caaggtaaaa agaaagggct atctaggtta gatatcttga tagaaaatat ggggcgtgtc
    25741 aactatgggc ataagttctt agcggatacg caacgtaagg gaattcggac aggggtctgt
    25801 aaggatctgc atttcttact aaactggaaa cactatccac ttccactaga caatcctgag
    25861 aaaattgatt tttcaaaagg atggactcaa ggacaaccag ccttttacgc ttatgacttt
    25921 acagtcgaag agccaaaaga tacttaccta gacttgtctg agtttggtaa gggagttgcc
    25981 tttgtcaatg ggcagaatct aggacgtttt tggaacgttg gcccaactct ctcactttat
    26041 atccctcata gctatctcaa ggaaggtgcc aaccgcatca ttatctttga aacagaaggt
    26101 caatataaag aagagattca tttaactcgt aaacctacac taaaacatat aaagggggaa
    26161 aacttatgac aattgtagga tgccgtattg atggacgttt gatccacgga caagtagcca
    26221 atctttgggc tggaaaacta aatgtttcac gcattatggt tgtagacgac gaagttgtca
    26281 acaacgatat tgaaaagagt ggtttgaaac ttgcgacacc accaggtgtg aaattgagta
    26341 ttttgccagt tgagaaagct gcagccaata ttcttgctgg taaatacgat agccaacgtc
    26401 tctttatcgt ggctcgtaaa ccagaccgct tccttggctt ggtagaagca ggtgtaccac
    26461 ttgaaaccct taatgttggg aatatgtctc aaacaccaga aactcgttct attacacgtt
    26521 ctatcaacgt agtagacaag gatgtggaag acttccacaa actggcagaa aaaggtgtta
    26581 aacttactgc tcagatggtt ccaaatgatc caatttcaga ctttttgagc ttattaaaat
    26641 aggaaaaaaa tttttaggag gtcattgtta tgatacaatg gtggcaaatt ttacttctca
    26701 ctttgtactc agcttatcaa atctgtgatg agttgacgat cgtttcatct gcaggttccc
    26761 ctgtatttgc tggtttcatt actggtttaa tcatgggaga tgtgactact ggtttactta
    26821 tcggtggtaa cttgcaactg ttcgttcttg gggttggtac cttcggtggt gcttctcgta
    26881 tcgacgcaac ttctggtgcg gttcttgcga cagccttctc tgtttcacaa ggaattgatg
    26941 caccgcttgc cattactaca atcgctgtac cagtagcagc tctcttgact tacttcgacg
    27001 ttcttggtcg tatgactact accttcttcg ctcaccgtgt ggatgctgca atcgaacgct
    27061 ttgactataa aggtattgaa cgcaactact tgcttggtgc gattccgtgg gctctatctc
    27121 gtgcccttcc agtcttcttt gcccttgctt ttggtggtgc ctttgtacaa tcagtagtag
    27181 acttcgttga agcctacaaa tgggttgcag atggcttgac acttgcagga cgtatgcttc
    27241 caggtcttgg atttgcaatc ttgcttcgtt accttccagt taaacgtaac cttcactacc
    27301 ttgctatggg atttggtttg acagctatgt tgactgttct ttactcatat gtaacaggtc
    27361 ttggtggcgc tgttgctggt atcgtaggta ctcttcctgc tgaagttgct gaaaaaattg
    27421 gtttcgtgaa caacttcaaa ggtttgtcta tgattggtat ttctatcgta ggtattttcc
    27481 ttgcagtgct tcacttcaaa aatagccaaa aagtagctgt agcagcacct tctacaccat
    27541 cagaaagtgg ggaaatcgaa gatgacgaat tctaattaca aacttacaaa agaagatttt
    27601 aatcaaatca acaaacgtag cttgtttact ttccaattag gttggaacta cgaacgtatg
    27661 caagcttctg gttaccttta catgatcttg cctcagttgc gtaaaatgta tggtgatgga
    27721 actcctgaat tgaaagaaat gatgaaagtt catactcaat tcttcaatac ttcaccattc
    27781 ttccatacca ttatcgctgg ttttgacctt gccatggaag aaaaagatgg tgtaggttca
    27841 aaagacgctg ttaacggtat caagacaggt ttgatgggac cattcgctcc tcttggggat
    27901 acaatctttg gttcacttgt acctgctatc atggggtcag tcgcagcaac tatggctatc
    27961 gctggccaac cttgggggat cttcctttgg attgcagttg cagtagcgta tgacatcttc
    28021 cgttggaaac agttggaatt tgcttacaaa gaaggggtta accttatcaa caacatgcaa
    28081 agtaccttga cagctttgat tgacgctgca tctgtacttg gtgtcttcat gatgggtgct
    28141 cttgtagcaa cagtgattaa ctttgaaatt tcttacaagt tgccaatcgg tgaaaagatg
    28201 attgatttcc aagacatctt gaaccaaatc ttcccacgtt tgcttccagc aatctttact
    28261 gcctttatct tctggttgct tggtaagaaa ggtatgaact ctactaaagc tatcggtatt
    28321 attatcgtac ttgctttggc tctttctgcc cttggtcact ttgcacttgg aatgtaattc
    28381 cttatgacta aatcattaat tttggtgagc catggtcgct tctgtgagga gcttagaggt
    28441 agcacagaaa tgattatggg cccacaagac aacatttaca cagtagctct tcttccagaa
    28501 gatggcccag aagaatttac tgctaaattt gaagctgtta ttgaaggatt ggatgatttc
    28561 ctagtttttg cggatcttct cggtgggaca ccttgtaatg tggtgagtcg cttgatcatg
    28621 gaaggtcgtg atattgacct ttacgcaggg atgaatcttc caatggtgat tgaatttatc
    28681 aatgcgagcc ttacaggcgc agatgcggac tacaagagcc gtgctgcaga aagcattgtg
    28741 aaagttaatg acctgttagc gggcttcgat gatgacgaag atgaataata ctcttcgaaa
    28801 atctcttcaa actacgtcaa cgtcgcctta ccgtaggtat atgttactga cttcgtcagt
    28861 cttatccggc aacctcaaaa cggtgttttg agctgacttc gtcagtctta tccggcaacc
    28921 tcaaagcagt gctttgagca gcctgcggct agtttcctac agattttagt tggaactcga
    28981 ttcaattcat gtgacaacgt gaaaatcgtt agagcatttt atatagaata tacatgggaa
    29041 tggagcttac tcccattcct atatttaata gaaaaagagg aactcaatgc tacattatac
    29101 aaaagaagac ttgctcgaat tgggtgcaga aatcactacg cgtgaaatct accaacagcc
    29161 tgatgtatgg agagaagctt ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt
    29221 cctacaagaa atcgctgata aacatgacta tattaaggtt atcttgacag gtgctgggac
    29281 ttctgcttat gtgggagaca ccttgctacc ttactttaag gaagtctatg acgaacgcaa
    29341 atggaatttc aatgctattg cgacaacaga tatcgttgcc aatccagcaa cctatttgaa
    29401 aaaagatgtg gcaactatcc ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt
    29461 ggcgactgtt gatttggcca aatccttggt ggatgagctt tatcaagtga cgattacttg
    29521 tgcaacagat ggtaaattgg ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt
    29581 gcaaccagct gtctctaatg atgctggatt tgccatgact tctagcttta cgtctatgat
    29641 gttgacagct ctcttggtct ttgatcctac agaatttgct gttaagtctg aacgttttga
    29701 agttgtatct agtcttgccc gtaaagtttt agacaaggca gaagatgtca aagagctcgt
    29761 tgatttagac tttaaccgtg tcatctatct aggcgctggt cctttctttg gacttgctca
    29821 tgaagctcag ctcaagattt tggaattaac tgctggtcaa gttgcgacca tgtatgaaag
    29881 cccagttggc ttccgtcacg gtccaaaatc tcttatcaac gacaatacag ttgttttggt
    29941 ctttggtaca acgacagact acactcgtaa gtacgacttg gacttggttc gtgaagttgc
    30001 tggtgaccag attgctcgtc gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa
    30061 tgtcaaagaa gtggcccttg gttgtggcgg tgtcttgaat gatatttacc gtgtcttccc
    30121 ttacatcgtt tatgcccaac tctttgccct attgacttca ctcaaggtag aaaataaacc
    30181 agatacaccg tctcctacag gtacagtaaa ccgtgtagta caaggtgtca taattcacga
    30241 atattaaaag taagacagtg tttatgaatt cttgacaaga ggatttgtaa attatcagat
    30301 aaaccataga ttgtcagtac gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg
    30361 agaacagaat gaaagcatac acagagcgtg tatttggaaa tgttgagggc gaggatgtct
    30421 tggcctatcg atttgagaca gacggtggct accaacttga ggttatgact tatggcgcga
    30481 ccatcttgcg ctatgtcgca cctgacaagg ctggaaattt tgccaatgtt atcttgggat
    30541 ttgatgactt tgatagttat gtaggcaata gtcccaagca tggagcaagt gtaggtcctg
    30601 tagcgggtcg tattgcaggt gcgacctttg agctcaatgg taagacctat gaccttgagg
    30661 ttaataatgc tagcaactgt aatcacagtg gttcaactgg ttgggattcc agcttgtttg
    30721 aagttgaaga agtaagcgat catggcttga ctctctacac agaacgtaca gatgggacag
    30781 gagggttccc tggaaatctc aagatttgga tcagttatca cttggaagaa actggtgcct
    30841 atgaaattag ctacaaggta acgaccgatc aggatacgct ggtcaatcca accaaccaca
    30901 gctatttcaa cttgtctggt gatttcacgc agacgattga ccgtcatgtc ttccaactaa
    30961 acacagaggg catttactca atcactcctg acggtgttcc tgccaaaact ccagaagcca
    31021 accgtgatgt ggtcaaacac atctacaatg gtaccttgtt gaaggatatc tttgcagaag
    31081 aagatgagca aatccagctg gcatcaggtt tggatcaccc atttgccctt cctgtaggcc
    31141 atgacaatgc tggattcctt tatgaccaaa attcaggtcg cttcctgctt ttcaagacag
    31201 aagctccttg ctttgtggtc tacacagcaa actttgtgga tgaaagtgtc atcataggag
    31261 gtcagccaat gctacagcac aatgggattg ctcttgaagc gcaagcttta ccagatgcca
    31321 ttcacagtga ccttaaaggc caagtcattc ttaaagctgg tcaaaccttc accagtaaga
    31381 cacgttatga acttgttgtg aaataaaaaa gctggtcaaa aagtctttaa aattaaaata
    31441 acgcatattg tcaggtgatg aaaagtttga tactatgcgt tttattatga aatgatttac
    31501 tttatcttat cctgaaatgg tgttattttt gagttatctg gcttgacttt cttgatggaa
    31561 attatataat agttgtaata acaataatta caacgagaaa agaggaccat ttatgaccta
    31621 tgaatacaag agtcacattt atttggcaga gacagtttta aatgtaaagg atttggccag
    31681 tcaaacagcc ttttatcagc aagttattgg tttagaaatc ttatctcaaa ctgagacaga
    31741 gtccattcta ggccttggtg gaaaagtctt ggtacagctg attcaagcac aagagagcgg
    31801 agaagtgagg gaacattatg gtctttacca tttggccatt ctcttgccca cacgcaaggc
    31861 tttggctgat gtcttgaaac acctgacaga tttacagatt cctcttgtcg gcggtgcaga
    31921 ccatggttac agtgaagcta tttacttgga agatttggag ggaaatggca ttgaactcta
    31981 tcgagataag ccagtttcca catgggatat tcgagaagat ggacgcatta tcggagtgac
    32041 ggaggctctt gcggcgcagg acatttatga gttgggggaa agagtagagc cctttatcct
    32101 ggcagaaggt acaagaatgg ggcatattca tctttccgtc aaggatagtc gaaagtccag
    32161 ccagttttat caaaaggtgt tagggctaga ggataaattc agtgtgccta gcgctagttg
    32221 gattgcggct ggagattacc atcatcattt agcagttaac gaatggggag gaaaaggtct
    32281 ggcttcgcgt aagcaaggct taccaggttt agcctactat gtcatcgaag tcgcacataa
    32341 agaagaactg ttaacgattg tccaacgagc acaagaagtt gacgcaccaa tcaaatggat
    32401 gacatcgagc caattggaaa tcacagactc agatggcatc gtgacccgta ttcgtttagc
    32461 aaggtaaaat taggaatttc taataagtta taagtattgc tagtttgctt tttgaacggt
    32521 ctttggtaac agaactgcgt gagctggatg ggtgagaatt ttgacaaaga agctgattag
    32581 agatataatg aagaaaaatc gagcaaggaa aaagaaatga caaattcaaa gtatattact
    32641 tgtttgaaac gttcagaggg ccagttgtgt gggattcaaa agatgattga aggagatcgt
    32701 gactgtgctg atattgtgac gcaactgaca gcagtgagat ctagtgtaga gcgcgtgatt
    32761 gagatgataa ttaccgaaaa tcttactgaa tgtatcaatc agccactaga tgattctgaa
    32821 gctcaaaagg aacgcctaga aaaggctatc cgatacttga ttaaacggaa ataaatgaat
    32881 gttttgagac gatatgtgca aaggtctatt aactattaga atagtttaat gtgagtcaaa
    32941 agaagttgta aaaaatcttt aaaattaaaa aaacgcatag tatcaggtgt tgaatgtact
    33001 gacccccaaa agttagattt tttctgtcta acttttgggg gtcagttcat aagaaccttg
    33061 gtaatatgcg ttttattatg tagaaactta tactcttcga aaatctcttc aaaccacatc
    33121 agcttcacct tgccgtagat atggttactg acttcgtcag ttctatccac aacctcaaaa
    33181 cagtgttttg agctgacttc gtcagttcca tccacaacct taaaacagtg ttttgagcag
    33241 cctgcggcta acttcctagt ttgcacttta attttcattg agtattactt catcttctca
    33301 tgaaattgag tttttgccca gctcctcttg attattctac ttgaccgggc caagtattca
    33361 taccaccttc tacgttggta acggtgaggc cttgggagct gagaaattgg caggtagatg
    33421 cagagcggac tcctccttga caaataacat agtattcatg gtcaggtttg agttctttgt
    33481 agccttgctc taaggtactt aatggaagat ttttggcacc tggtgcatgt cctgcttgga
    33541 attcatgtgc ttcacggaca tcgataagtt ctagattttc attttagtat tttccataaa
    33601 agtcagccat gctgatacta gtttccatat tctactcctt ctgggttagc cattttgtat
    33661 agtgaataag cgccgtcaag gttttggacg gtaaatcctg cttgcttgag gataggctct
    33721 gcgatatagc tgcgcaaacc actgtggcag ctgacgatgt aggcttgttt tttgtccagt
    33781 tcatcagctt cctccttgac actttgtcag tttttgatac aatagtacaa aattagagga
    33841 ggtgggctat gattcagaaa catgcgattc ccattttaga gtttgatgat aatcctcagg
    33901 cggttatcat gcccaatcac gaggggttgg atttgcagtt gccaaagaag tgtgtctatg
    33961 cttttttagg tgaggagatt gaccgctatg cgagggaagt aggggcgaac tgtgttggcg
    34021 aattcgtttc tgctaccaag acctatccag tctatgtcat caactacaag ggtgaggagg
    34081 tctgtctggc tcaggctcct gttggctccg ctccagcagc ccagtttatg gattggttga
    34141 ttggctatgg tgtggagcag attatctcta ctgggacctg tggtgtccta gctgatatag
    34201 aggaaaatgc ctttctagtc cctgttcgcg ctttgcgaga tgagggagcc agttaccact
    34261 atgtggcacc ttgtcgttat atggaaatgc agccagaggc tattgctgct attgaggaag
    34321 ttttggaaga cagagggatt ccttatgaag aagtcatgac ctggacgaca gacggttttt
    34381 accgagaaac ggctgaaaag gtggcttatc gtaaggaaga aggctgtgct gttgtggaga
    34441 tggagtgttc tgctcttgcg gcagtagctc aattgcgtgg ggttctctgg ggtgaattgt
    34501 tgttcacagc agattctcta gcggacttgg accagtacga cagtcgtgac tggggctcgg
    34561 aagcttttaa taaggcgcta gaactgagtt tagcaagtgt tcaccacctt tagttgtaca
    34621 ggcaaaggat ttgttttatc ataaaatgtc tagctcatac ttttcaaaaa tatgtttaaa
    34681 cgaggtcacc ttcctcttgt cctaggcatg ttgaggttgg gaaaaatctt taaaatcaga
    34741 aaaacgtatc atatcaggtg atgaaaattt tgatactatg cgttttatgt tggtaagatt
    34801 tagagtgaga tgaaatgata ctcttcgaaa atctcttcaa accaggtcag cttcaccttg
    34861 ccgtaggtat atgttactga cttcgtcagt cttatccggc aacctcaaaa cggtgttttg
    34921 agctgacttc gtcagttcta tccacaacct caaaacagtg ttttgagcaa cctgtgacta
    34981 gctttctaag cgatgccttg gttctcattg cctataatca aaaagagaaa ttttctcctg
    35041 aaaagcatat agagtagctg gcgttaaaag ctcctgtctt gcttttttga cctatagtca
    35101 catctatcaa gtattgttct tgcctaagct atcaataaaa aggtggcatt ttttaggctt
    35161 ggtgttagtg aattttgcct tatcctatct aagtcatttc gagcttttta tggtacaatg
    35221 gaaacatgtt attcaaatta tctaaggaaa aaatagagct aggcttatct cgtttatcgc
    35281 cagcccgtcg tatttttttg agttttgcct tggtcatttt actaggctct cttcttttga
    35341 gcttgccctt tgtccaagtt gaaagctcac gagcgactta ttttgatcat cttttcactg
    35401 ctgtctctgc agtctgtgtg acaggtctct caacccttcc agtagctcac acctataata
    35461 tctggggcca aataatctgt ttgctcttga ttcagatcgg tggtctaggg ctcatgactt
    35521 ttattggggt tttctatatc cagagcaagc aaaagcttag tcttcgtagc cgtgcaacta
    35581 ttcaggatag ttttagttat ggagaaactc gatctttgag aaagtttgtc tattctattt
    35641 ttctcacgac ctttttggtt gagagcttgg gagctatttt gcttagtttt cgccttattc
    35701 ctcaacttgg ctggggacgt ggtcttttta gttccatttt tctagcgatc tcagccttct
    35761 gtaatgccgg ttttgataat ttagggagca ccagtttatt tgcttttcag accgatttac
    35821 tggtcaatct ggtgattgca ggcttgatta ttacaggcgg ccttggtttt atggtctggt
    35881 ttgatttggc tggtcatgta ggaagaaaga aaaaaggacg tctgcacttt catacgaagc
    35941 ttgtactatt gttgactata ggtttgttgt tatttggaac ggcaactact ctctttcttg
    36001 agtggaacaa tgctggaacg attggcaatc tccctgttgc cgataaggtt ttagttagct
    36061 tttttcaaac agtgacgatg cgaacagctg gcttttctac gatagattat actcaggctc
    36121 atcctgtgac tcttttgatt tatatcttac agatgtttct aggtggggca cctggaggaa
    36181 cagctggggg actcaagatt acgacatttt ttgtcctctt ggtctttgca cgaagtgagc
    36241 ttctaggctt gcctcatgcc aatgttgcga gacgaacgat tgcgtcgcga acggttcaaa
    36301 aatcctttag tgtctttatt atctttttga tgagcttctt gataggattg attctgctag
    36361 ggataacagc caaaggcaat cctcccttta tccacctcat atttgaaacc atttcagctc
    36421 ttagtacagt tggtgtaacg gcaaatctga ctcctgacct tgggaaattg gctctcagtg
    36481 ttatcatgcc acttatgttt atgggacgaa ttggtccctt gaccttgttt gttagcttgg
    36541 cagattacca tccagaaaag aaagatatga ttcactatat gaaagcagat attagtattg
    36601 gttaagaaag gaaagagcat gtcagatcgt acgattggaa ttttgggttt gggaattttt
    36661 gggagcagtg tcctagctgc cctagccaag caggatatga atattatcgc tattgatgac
    36721 cacgcagagc gcatcaatca gtttgagcca gttttggcgc gtggagtgat tggtgacatc
    36781 acagatgaag aattattgag atcagcaggg attgatacct gcgataccgt tgtagtcgcg
    36841 acaggtgaaa atctggagtc gagtgtgctt gcggttatgc actgtaagag tttgggggta
    36901 ccgactgtta ttgctaaggt caaaagtcag accgctaaga aagtgctaga aaagattgga
    36961 gctgactcgg ttatctcgcc agagtatgaa atggggcagt ctctagcaca gaccattctt
    37021 ttccataata gtgttgatgt ctttcagttg gataaaaatg tgtctatcgt ggagatgaaa
    37081 attcctcagt cttgggcagg tcaaagtctg agtaaattag acctccgtgg caaatacaat
    37141 ctgaatattt tgggtttccg agagcaggaa aattccccat tggatgttga atttggacca
    37201 gatgacctct tgaaagcaga tacctatatt ttggcagtca tcaacaacca gtatttggat
    37261 accctagtag cattgaattc gtaaagaggg atgacccctc ttttttgatg cccaagatgg
    37321 caaatagaga cagaagcccc ttgtcttcta gtaaaagttc ttcaaaggct ggactttatg
    37381 gtaaaataga aggaagtgac aagagagagt aatactcaat gaaaatcaaa gatcaaacta
    37441 ggaaactagc tgcgggctgc tcaaaacact gttttgaggt tgtggataga actgacgaag
    37501 tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata
    37561 cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa gagtataaga aaaaatcagt
    37621 cccctaaagg agcagattat gaagttattg tctatcgcca tttctagcta taatgcagca
    37681 gcctatcttc attactgtgt ggagtcgcta gtgattggtg gtgagcaagt tgggattttg
    37741 attatcaatg acgggtctca ggatcagact caggaaatcg ctgagtgttt agctagcaag
    37801 tatcctaata tcgttagagc catctatcag gaaaataaat gccatggcgg tgcggtcaat
    37861 cgtggcttgg cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg
    37921 gatcctcgtg cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa
    37981 gaggtggatg tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag
    38041 agtatgagtt acgattcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga
    38101 aatttctcca aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg
    38161 cgtgctagcc agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt
    38221 acgccccttc agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg
    38281 attgggcgtg aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa
    38341 ctcaaggtca atcgactctt gatagaccaa cttgatttgt cccaagtgag tcatcccaaa
    38401 atgcgagaat atctgctgaa tcatattgaa ctcacgacgg tgatttccag taccctgctc
    38461 aaccgatctg gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag
    38521 cagaaaaatc cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa
    38581 cattctgtct tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt
    38641 tatggattta attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt
    38701 cttagtcctt tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa
    38761 ggagaatcct atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct
    38821 cagtgtcggt gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc
    38881 aagttctgta cgtgccgatg ggctcaatcc aaccccaggt caagtcttac ctgaagagac
    38941 accgggaacg aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc
    39001 gaaacctgag ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga
    39061 agtgagcgag gaaacaagcc cttctagtct ggatacactt tttgaaaaag atgaagaagc
    39121 tcaaaaaaat ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga
    39181 tgggacacaa gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga
    39241 aaatacaaaa gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg
    39301 tcctttcact gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat
    39361 gttaactcgt ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc
    39421 taaaaatcct gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt
    39481 agacttaaat ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc
    39541 taatggtact caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc
    39601 tgacttgact aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc
    39661 taaagaaaca gttcaaaaag ccgttgcaga caacgttaaa gacagtatcg atgttccagc
    39721 agcctaccta gaaaaagcca agggtgaagg tccattcaca gcaggtgtca accatgtgat
    39781 tccatacgaa ctcttcgcag gtgatggcat gttgactcgt ctcttgctca aggcatctga
    39841 caaggcacca tggtcagata acggcgacgc taaaaaccca gccctatctc cactagg
//
LOCUS       DAVLZG010000011        38326 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLZG010000011 DAVLZG010000000
VERSION     DAVLZG010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.011"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            2..74
                     /locus_tag="VYO72_000548"
     tRNA            2..74
                     /locus_tag="VYO72_000548"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VYO72_000549"
     tRNA            99..171
                     /locus_tag="VYO72_000549"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VYO72_000550"
     tRNA            177..258
                     /locus_tag="VYO72_000550"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VYO72_000551"
     tRNA            277..349
                     /locus_tag="VYO72_000551"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VYO72_000552"
     tRNA            372..443
                     /locus_tag="VYO72_000552"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VYO72_000553"
     tRNA            451..536
                     /locus_tag="VYO72_000553"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VYO72_000554"
     tRNA            546..619
                     /locus_tag="VYO72_000554"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VYO72_000555"
     tRNA            635..708
                     /locus_tag="VYO72_000555"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VYO72_000556"
     tRNA            714..787
                     /locus_tag="VYO72_000556"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VYO72_000557"
     tRNA            801..874
                     /locus_tag="VYO72_000557"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VYO72_000558"
     tRNA            885..974
                     /locus_tag="VYO72_000558"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            985..1058
                     /locus_tag="VYO72_000559"
     tRNA            985..1058
                     /locus_tag="VYO72_000559"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1019..1021,aa:Met,seq:cat)
     gene            1062..1134
                     /locus_tag="VYO72_000560"
     tRNA            1062..1134
                     /locus_tag="VYO72_000560"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Phe,seq:gaa)
     gene            1154..1224
                     /locus_tag="VYO72_000561"
     tRNA            1154..1224
                     /locus_tag="VYO72_000561"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Gly,seq:tcc)
     gene            1260..1333
                     /locus_tag="VYO72_000562"
     tRNA            1260..1333
                     /locus_tag="VYO72_000562"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1294..1296,aa:Ile,seq:gat)
     gene            1340..1427
                     /locus_tag="VYO72_000563"
     tRNA            1340..1427
                     /locus_tag="VYO72_000563"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1374..1376,aa:Ser,seq:gct)
     gene            complement(1553..2488)
                     /locus_tag="VYO72_000564"
     CDS             complement(1553..2488)
                     /locus_tag="VYO72_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1706982.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2485..3345)
                     /locus_tag="VYO72_000565"
     CDS             complement(2485..3345)
                     /locus_tag="VYO72_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1706983.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            3453..5615
                     /locus_tag="VYO72_000566"
     CDS             3453..5615
                     /locus_tag="VYO72_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1706984.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHITLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5707..6966
                     /locus_tag="VYO72_000567"
     CDS             5707..6966
                     /locus_tag="VYO72_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1706985.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6980..7846
                     /locus_tag="VYO72_000568"
     CDS             6980..7846
                     /locus_tag="VYO72_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1706986.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            7860..8693
                     /locus_tag="VYO72_000569"
     CDS             7860..8693
                     /locus_tag="VYO72_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1706987.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8993..10435
                     /gene="gtfA"
                     /locus_tag="VYO72_000570"
     CDS             8993..10435
                     /gene="gtfA"
                     /locus_tag="VYO72_000570"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1706988.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTMLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            10573..11766
                     /locus_tag="VYO72_000571"
     CDS             10573..11766
                     /locus_tag="VYO72_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1706989.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12452..14431
                     /locus_tag="VYO72_000572"
     CDS             12452..14431
                     /locus_tag="VYO72_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1706990.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            14498..15994
                     /locus_tag="VYO72_000573"
     CDS             14498..15994
                     /locus_tag="VYO72_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1706991.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15994..16920
                     /locus_tag="VYO72_000574"
     CDS             15994..16920
                     /locus_tag="VYO72_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1706992.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16929..17996
                     /locus_tag="VYO72_000575"
     CDS             16929..17996
                     /locus_tag="VYO72_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706993.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18007..18933
                     /locus_tag="VYO72_000576"
     CDS             18007..18933
                     /locus_tag="VYO72_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1706994.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            19500..20360
                     /locus_tag="VYO72_000577"
     CDS             19500..20360
                     /locus_tag="VYO72_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1706995.1"
                     /translation="MSQFITHQSLYATREGFVDKLAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELGRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            20372..21265
                     /locus_tag="VYO72_000578"
     CDS             20372..21265
                     /locus_tag="VYO72_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1706996.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            21278..22081
                     /locus_tag="VYO72_000579"
     CDS             21278..22081
                     /locus_tag="VYO72_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1706997.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(22114..22824)
                     /gene="treR"
                     /locus_tag="VYO72_000580"
     CDS             complement(22114..22824)
                     /gene="treR"
                     /locus_tag="VYO72_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1706998.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            23009..24976
                     /gene="treP"
                     /locus_tag="VYO72_000581"
     CDS             23009..24976
                     /gene="treP"
                     /locus_tag="VYO72_000581"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1706999.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATNPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            25154..26779
                     /gene="treC"
                     /locus_tag="VYO72_000582"
     CDS             25154..26779
                     /gene="treC"
                     /locus_tag="VYO72_000582"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1707000.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMTDYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            27035..27283
                     /locus_tag="VYO72_000583"
     CDS             27035..27283
                     /locus_tag="VYO72_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1707001.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            27490..28284
                     /gene="racE"
                     /locus_tag="VYO72_000584"
     CDS             27490..28284
                     /gene="racE"
                     /locus_tag="VYO72_000584"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1707002.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            28281..29252
                     /locus_tag="VYO72_000585"
     CDS             28281..29252
                     /locus_tag="VYO72_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1707003.1"
                     /translation="MTNKIYEYKDDRDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            29228..29749
                     /locus_tag="VYO72_000586"
     CDS             29228..29749
                     /locus_tag="VYO72_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1707004.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            29746..30207
                     /locus_tag="VYO72_000587"
     CDS             29746..30207
                     /locus_tag="VYO72_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1707005.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            30198..30938
                     /gene="xerD"
                     /locus_tag="VYO72_000588"
     CDS             30198..30938
                     /gene="xerD"
                     /locus_tag="VYO72_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1707006.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30938..31666
                     /locus_tag="VYO72_000589"
     CDS             30938..31666
                     /locus_tag="VYO72_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1707007.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            31685..32254
                     /locus_tag="VYO72_000590"
     CDS             31685..32254
                     /locus_tag="VYO72_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1707008.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            32241..32963
                     /locus_tag="VYO72_000591"
     CDS             32241..32963
                     /locus_tag="VYO72_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1707009.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVVNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32963..33205
                     /gene="yidD"
                     /locus_tag="VYO72_000592"
     CDS             32963..33205
                     /gene="yidD"
                     /locus_tag="VYO72_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1707010.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(33430..34395)
                     /locus_tag="VYO72_000593"
     CDS             complement(33430..34395)
                     /locus_tag="VYO72_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707011.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(34491..35243)
                     /locus_tag="VYO72_000594"
     CDS             complement(34491..35243)
                     /locus_tag="VYO72_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1707012.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(35240..36196)
                     /locus_tag="VYO72_000595"
     CDS             complement(35240..36196)
                     /locus_tag="VYO72_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1707013.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(36186..37145)
                     /locus_tag="VYO72_000596"
     CDS             complement(36186..37145)
                     /locus_tag="VYO72_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707014.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(37568..38269)
                     /locus_tag="VYO72_000597"
     CDS             complement(37568..38269)
                     /locus_tag="VYO72_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1707015.1"
                     /translation="MTKTILVTGGTSYISSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
BASE COUNT        10972 a         7207 c         8598 g        11549 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag ataacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttcttttt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttaacgcggg atggagcagc taggtagctc gtcgggctca
     1021 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
     1081 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattttat
     1141 tgatagtatt tatgcgggtg tagtttagtg gtaaaactac agccttccaa gctgttgtcg
     1201 cgagttcgat tctcgtcacc cgctttgaac tttgttcaaa ttaccaagtt ttttaacttg
     1261 ggcgcgtagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt
     1321 ccactcgtgc ccattaattg gagaattact caagaggctg aagaggacgg tttgctaaat
     1381 cgttaggtcg ggtaactggc gcaagggttc gaatccctta ttctccgttt taatgagagt
     1441 ttgtaactct cttttttgtt tttagagaca ataaaacttc agatccgtaa aacttaattg
     1501 aattactaat ctgaagttat ttttatatcg tttatattat aattgtgtta ttttacttcc
     1561 aactattgag agaaatttcg ccactattta gccagatttc ttttccgtta tcacattgaa
     1621 ctaaaagttt tccattttct gagatgtctt tagcaagtcc cttgtagtct ttttgctcta
     1681 gtgtgaaagt gacttctttt cctagaatga atgactgttt tttgtatagg tataatagct
     1741 cttctgctgg tgtttcgaag aaagcacgcc agatttctat gatcaattca ttccttgtta
     1801 taggagctgt agctttaaat aagctggcag ctttttcttt taattcctga gggaagtctt
     1861 taatagtgaa attgatacct actccaataa tgatatctgt gactaagcca gtttctacag
     1921 aggtcattgc ttcagtaagg attcctccaa ttttatgatt gtttagatag atatcattga
     1981 cccattttat atcgacatct attaaagtta ggttcttaat ggctttgtag acagctccag
     2041 ctacaagtag tgtgtaggat ggtaatttgt cataggggag atttggttta agatggagtg
     2101 tcatataaat tccaccttgt ggtgagtaga aggaacgttg aaaacggcct cggcctgctg
     2161 tttgatagga agctagatag agagtatttg cttcatggcc taaatcaatt gcttcttttg
     2221 catctagttg tgttgatttt gtttcgggtt taaagctgac tttaattgga agattttctt
     2281 ctagaatctc tggaagaata aggtcaccat tcattagttt atatcctcta tttttgatac
     2341 tattaatttc aatgccttct tgttctagtc gcttgatagc tttccaaatt gatgttcggc
     2401 ttagggatag tttttctgcg attttttctc cgctgatata gtcggtttct ttagatagga
     2461 tttggtagac agcttggtag gatttcataa tgttgccttt ctcactagtt ggtattgaga
     2521 gtattctttt cttgtatgac ttggagactg attaaagtat tgtttataag ctttcgaaaa
     2581 atggagtgga tctgaaaaac ctaccgagta tgcaattacc ttgatggact cttgggtatt
     2641 ttcgagaagt tgtctagctc ggtgcattcg aacgtagagt aggtattctt tgggtgataa
     2701 ggtattaaat tctttgaata cgcttgataa gtagcttctg tgaacggata gttcttttgc
     2761 taaatcttga attgtaagtg attgaggata gtggctatca attaatcgtt tgcattcaag
     2821 atagagttgg tgggttgatg aaatattctt ttttttctga ttgggagcaa tagttcccag
     2881 atgaaacatc agttcatgaa gttgtcccat gatatggagt tgagctaatt cacttgattt
     2941 tgtaatctga gcgaagcgga caatgtctga gatgagtttt gcagtagtct gggtatgaca
     3001 agtttcagat tggatgagat aggattgatc agaaatttga gaaagagcaa aataatcagg
     3061 ggatttccct ccagtgattc ctaaccagta gtaggcccaa ggttctttac tatctgcttg
     3121 ataaaaggtt agttcctctg gttttaatag aaagaaatct ccttctttta aatcaacaat
     3181 tttacccttg taatgaaatt ttccttgtcc tttactaatg taatgtagga cgtatgtatc
     3241 acgaatggct ggaccaaaag agtaattagg tgtgcattcc tcatatccat aaaagcttag
     3301 ggcaaggtca attgttccag tctggtattc tgaaaaaact agcatgtgct acctcctacc
     3361 taacatttta ccatattctt gagacatttt tctattttgg aaagcgattt caggtgataa
     3421 aatataatca ataaagtgat gaggtgaagt aaatgggagt taggatagag aataatctat
     3481 tttatgttga gagtaaaaat ctaagtttga ttattgaaaa tcgaaatggc tacttacttt
     3541 tgaaacattt aggaaagact attaagaact ataaaggttc caatagtgtt tatgaacgag
     3601 accatgcctt ttcaggaaat ccaacggcta ctaatcgaac ctttagttta gatactcagc
     3661 gacagatttt tggacaacat ggcttaggag attttaggaa accaactata caggttcagc
     3721 atagtgtaac tgaagtaaca gactttcgat ttgtagaagc aaagatttta aaaggtcaga
     3781 atggtccaca gggcttacct tctccacata gcatggacga tacagagact cttgtcttaa
     3841 tgttagaaga ttctaaggct caacttagtc tgactttgta ttatactact tttaataatg
     3901 atgcgactat tgctagctac agtaaattag ataataatag taatcaggaa gttgtcatcc
     3961 ataaagattt ttcttttatg gctgattttc cagctgcaga ttacgaaata gtaactctgc
     4021 agggtgctta tgctcgtgaa aagactgtta gacgtcaaca ggtagaacaa ggaatctttt
     4081 cgattagttc aaaccgaggt gcttctggtc atgctcaaac accagctctt ctactatgcg
     4141 aacaaggagt cacagaggat gctgggaatg tgtttgctat tcaactaatg tatagtggca
     4201 actttgaagc ttttgttcaa aaaaatcaat tgaatgaagt tcgggtggct attggcatta
     4261 atccagaaaa cttttcttgg aagttagccc ctgaggaata ctttgaaaca ccggtagctt
     4321 tagtgactca ttcagatcag ggattaactg gtattagtca tgaaagtcag aattttgtac
     4381 tgaagcacat tactctaagt gaattttcta aaaaagaacg tccaattcta atcaataact
     4441 gggaagctac ttactttgac tttcagagag aaaaactgtt agagttagca gatgaagcta
     4501 agaaagttgg cattgaactt tttgtattag atgatggttg gtttggcaat cgttttgatg
     4561 ataatcgtgc tttaggtgat tgggttgtta atgaggaaaa actgggtgga agtctagaaa
     4621 gtctgatttc agctatccat gaaagaggtt tgcagtttgg actttggtta gaacccgaaa
     4681 tgatttctgt agatagtgat ttgtatcgtc aacatcctga ctgggctatt caggttcctg
     4741 attatgagca tacttattct cggaatcaat tagtacttaa tcttgccaat cctcaggtag
     4801 tagaatactt gaaaagtgtc ttagatcaac tcctatctta tcatgagatt gattacatta
     4861 aatgggatat gaaccgcaat atcactaagc tagggaatgg attaacttat ctagagacac
     4921 agatgcaatc tcatcagtac atgctgggac tttacgaact cgtttcttat ctgacagaga
     4981 agcacagcca tattctcttt gagtcctgct ctggtggtgg tggacgaaat gatcttggta
     5041 tgatacgcta tttcccacaa gtctgggcta gtgataatac tgatgccatt gcacgtttac
     5101 caattcaata cggttcatcc tatctctatc caaccatttc tatgggggct catgtgtcag
     5161 cagtaccgaa tcatcagatg ggacgaatga caccattaga aacacgtggc catgtagcaa
     5221 tgatgggaaa tttgggctat gagcttgatt tgacaaattt atcagatgaa gagaaagcta
     5281 cgattgctaa tcaggtgaac ttgtataaag aattacgacc agtagttcag ttaggacagc
     5341 agtatagact aattaatcct gatactgcat ccaatgaagc agctgtacaa tttaattacg
     5401 gaaatcaaac gattgtaacc tacgttcgcg ttttatctgt tgtagagacc atggaaacaa
     5461 ctttaaaatt aaaagatttg gatgaagagg gactatataa attacaggaa aatggcgaag
     5521 tttactcagg tgcagaacta atgtatgcgg gcttaactgt tatcttatcc caaggagatt
     5581 ttttgagtag acagtatatt tttagaaaac tatgatatgt actgacccca aaagttagat
     5641 ttattctgtc taacttttgg ggtgcagttc aataagggtg tataaattta taaaggaggc
     5701 tttctaatgg aatggtataa aaaaatcgga cttcttgcaa ctacaggttt agctttgttt
     5761 gggctcggcg cttgctccaa ctatggtaaa tctgcggatg gcacagtgac catcgagtat
     5821 ttcaaccaga aaaaagaaat gaccaaaacc ttggaagaaa tcactcgtga ttttgagaag
     5881 gaaaacccta agatcaaggt caaagtcgtc aatgtaccaa atgctggtga agtattgaag
     5941 acacgcgttc tcgcaggaga tgtgcctgat gtggtcaata tttacccaca gtccatcgaa
     6001 ctgcaagaat gggcaaaagc aggtgttttt gaagatttga gcaacaaaga ctacctgaaa
     6061 cgcgtgaaaa atggctacgc tgaaaaatat gctgtaaacg aaaaagttta caacgttcct
     6121 tttacagcta atgcttatgg aatttactac aacaaagata aattcgaaga actgggcttg
     6181 aaggttcctg aaacctggga tgaatttgaa cagttagtca aagatatcgt tgctaaagga
     6241 caaacaccat ttggaattgc aggtgcagat gcttggacac tcaatggtta caatcaatta
     6301 gcctttgcga cagcaacagg tggaggaaaa gaagcaaatc aataccttcg ttattctcaa
     6361 ccaaatgcca ttaaattgtc ggatccgatt atgaaagatg atatcaaggt catggacatc
     6421 cttcgcatca atggctctaa gcaaaagaac tgggaaggtg ctggctatac cgatgttatc
     6481 ggagccttcg cacgtgggga tgtcctcatg acaccaaatg ggtcttgggc gatcacagcg
     6541 attaatgaac aaaaaccgaa ctttaagatt gggaccttca tgattccagg aaaagaaaaa
     6601 ggacaaagct taaccgttgg tgcgggagac ttggcatggt ctatctcagc caccaccaaa
     6661 catccaaaag aagccaatgc ctttgtggaa tatatgaccc gtccagaagt catgcaaaaa
     6721 tactacgatg tggacggatc tccaacagcg atcgaagggg tcaaacaagc aggagaagat
     6781 tcaccgcttg ctggtatgac cgaatatgcc tttacggatc gtcacttggt ctggttgcaa
     6841 caatactgga ccagtgaagc agacttccat accttgacca tgaactatgt cttgaccggt
     6901 gataaacaag gcatggtcaa tgatttgaat gccttcttta acccgatgaa agcggatgtg
     6961 gattaggagt agagagacta tgaaaaaagt attacaaaaa tattgggcat gggcttttgt
     7021 ggtcatcccc ctcttgttac aagcaatttt cttctatgtg ccgatgtttc aaggagcctt
     7081 ttacagtttt accaactgga caggattgac ttataactac aaatttgtcg gcttaaacaa
     7141 ctttaagctc ctcttcatgg atccaaaatt catgaatgcg attggcttta ccgcaatcat
     7201 tacgattgcc atggtggttg gtgagattgc actcgggatc ttcattgcgc gtgtcttgaa
     7261 ctctaaaatc aaaggccaaa ccttcttccg tgcttggttc ttcttcccag ctgttttatc
     7321 tggtttgaca gtggctttga tcttcaagca agtcttcaac tacggtcttc cagcgattgg
     7381 gaatgccctt catattgaat ttctccaaac cagtctttta gggactaagt ggggagcaat
     7441 ctttgcggct gcctttgtcc ttctttggca aggggtggct atgcccatca tcatcttcct
     7501 agctggtttg caatctattc caactgagat tacagaggca gcaaggattg atggtgcgac
     7561 tagcaagcaa gttttctgga acattgaatt gccttacttg ctaccaagtg tctctatggt
     7621 ctttatccta gccctaaaag gtgggctgac tgcctttgac caagtctttg ccatgaccgg
     7681 tggtggtcca aacaatgcca caacctcact tgggctcttg gtttataact atgcctttaa
     7741 aaacaaccaa ttcggttatg ccaatgccat tgccgtaatc ttgttcctct taattgtagt
     7801 gatttcgatc atccaattga gagtatctaa gaaatttgaa atttaagagg agaagcatga
     7861 tgaaacaaga tgaaagaaaa gccctgattg gcaaatacat tctattgatt ctaggatcgg
     7921 ttctgatttt agtgccgctc cttgctaccc tctttagttc cttcaaaccc actaaggata
     7981 ttgtagataa tttctttggc tttccaacca acttcacatg ggacaacttt agccgtctct
     8041 tagctgatgg gattggaggc tattattgga actctgtcgt catcactgtc ttgtctttac
     8101 ttgcagtaat gatctttatc cctatggcag cctactccat cgctcgcaat atgagtaaaa
     8161 gaaaagcctt taccatcatg tataccctct taatcctcgg aatcttcgta cctttccaag
     8221 tcatcatgat tccgattacg gttatgatga gtaaactcgg tttggctaat acctttggtt
     8281 tgatcttgct ctacttgacc tatgcgattc cacagaccct ctttctctat gttggctata
     8341 tcaaaatctc gattccagaa agtctggatg aagcagcaga gatcgatggg gctaatcaat
     8401 ttacaaccta tttccgcatc atcttcccaa tgatgaaacc gatgcatgcg acaaccatga
     8461 ttatcaatgc cctttggttc tggaatgact tcatgttgcc actccttgtc ttgaaccggg
     8521 attccaaaat gtggactctg cctttgttcc aatacaacta cgcaggccaa tatttcaacg
     8581 actacggacc aagctttgcc tcttacgtgg tcggcattat cagtatcacc attgtctatc
     8641 tcttcttcca acgccatatc atttcaggaa tgagcaacgg ggcagtgaag taatactcaa
     8701 tgaaaatcaa agagcaaact aggaagctag ccgcaggctg tacttgagta cggcaaggtg
     8761 aagctgacgt ggtttgaaga gattttcgaa gagctcatgg aatctatagt ctttgacaca
     8821 gaggaagagt ttagcttgtt gataattcta tgcagaaaac aagaaagtag tactttgttt
     8881 atcacagtct atattagtac gagtttgatg ataaatagag atttaaaatg aattttattt
     8941 atgaagccag atcatatgag acttggcttc aattagaaaa aggagagtaa tgatgccaat
     9001 tcaaaataaa accatgttga ttacctattc tgatagcctt ggaaataatc ttaaagactt
     9061 atatgataat ttggaagagc attttggaga tgctattgga ggagttcacc ttttaccatt
     9121 tttcccatca acaggtgatc gtggatttgc gccagttgac tacgacgaag tggactcagc
     9181 ttttggtgat tgggaggatg ttaagcgttt aggtgagaaa tattatctta tgtttgattt
     9241 tatgattaat catatttctc gtcaatccaa gtattataag gactatcaag aaaaacatga
     9301 agccagtgaa tttaaagctc tctttttaaa ctgggataag ttttggccag aaaaccgtcc
     9361 gacacagtct gatgtagatt taatttacaa gcgtaaggat cgtgcaccaa agcaagagat
     9421 tgtgtttgaa gatggttcag tggaacattt gtggaatacc tttggtgagg agcagattga
     9481 tcttgatgtg accaaagaag taactatgga atttatccgt aagaccattc agcacttggc
     9541 aagtaatggg tgtgatttga ttcgtctaga tgcctttgct tatgcagtga agaaattgga
     9601 tactaatgat ttctttgtgg aaccagatat ttgggattta ttggacaaag ttcgagatat
     9661 cgctgctgag tatgggacag agcttttacc tgagattcat gaacactatt cgattcagtt
     9721 taaaatagca gaccatgatt actatgttta tgattttgct cttccaatgg tgacacttta
     9781 tactctttac agttccagaa cagagcgttt ggctaagtgg ttaaagatga gcccgatgaa
     9841 gcaatttacg atgctagata cccatgatgg gattggagta gtagatgtca aggatatcct
     9901 gaccgatgag gagattgact atgcttcaaa tgaactctat aaggttggag ccaatgtcaa
     9961 acgtaagtac tctagtgccg agtataacaa cttagatatc taccaaatca attcaaccta
    10021 ctattcagcg cttggagatg atgatgtcaa gtattttctc gctcgtctaa ttcaagcttt
    10081 tgccccaggt attcctcagg tttactatgt gggtctatta gcaggcaaga atgacttgaa
    10141 attattagaa gaaactaaag aaggtcgaaa tattaatcgt cattactata gcaacgagga
    10201 aatagcaaaa gaagtgcaac gacctgttgt gaaggccctt ctcaatctat tttctttccg
    10261 taaccgttca gaagcctttg atctagaagg gactactgag atagagacac caacagctca
    10321 cagcattgta atcaaacgtc aaaataaaga taagtccgta acagcagtag tagaaattga
    10381 tttgcaaaat cagacttatc gggtaattga gaatggagtt gaagtatcat tttgaagcct
    10441 tgatatggtg gataaaatag ggtttttatt ttggaaaacg tttcctttgt tttcaaattg
    10501 ctaaaaaagt ggtacaatat aggatagctt actattatct gaatcagctg atttggagag
    10561 aaaggattca ttttgaaatc aataggcttt attgaaaagc tgaaggggtt gtctagtaaa
    10621 gagctgattt tattgggaat tatcctaagt atctttttac ccttttatct ttttgtagtt
    10681 gtactctgtt tatatattat cagtttgatt tttacaggag acatgaaaag tattcttcag
    10741 aaaatggggg agcatccgat gctgcttctt tttcttagct atagtactgt tatatccatt
    10801 cttgcacaaa attggatggg tcttgtggct tcagtaggaa tgtttctatt tactattttc
    10861 tttttgcact atcagtcgat tttatcccat aaattctttc gattgatttt gcagttcgtc
    10921 ttgtttggta gtgtcttgtc agctgctttt gccagtttag aacatttcca aattgtgaag
    10981 aaatttaact atgcttttct ttcacccaat atgcaggtgt ggcatcagaa ccgggcagaa
    11041 gtgaccttct ttaatcctaa ttattatgga attatttgtt gtttctgtat tatgattgct
    11101 ttctatctgt ttacaacgac caagttgaat tggttgaaag tattctgtgt gattgcaggc
    11161 tttgttaatc tctttggttt gaactttact caaaatcgaa ctgcctttcc tgctattatc
    11221 gctggagcaa ttatctatct ctttacgact attaaaaact ggaaggcctt ttggcttagt
    11281 attggggtct tcgcgattgg tttgagtttc ctcttttcta gtgatttggg agttcgaatg
    11341 ggtactttag actcttctat ggaagaacgc atttctatct gggatgctgg gatggccttg
    11401 tttaagcaaa atcctttttg gggtgaaggg ccattgacct atatgcactc ttatcctcgg
    11461 atacatgctc cttatcatga acatgcccac agtctttata ttgatacgat tctgagttac
    11521 ggaattgtgg gtaccatttt attagttttg tcttctgttg ctcctgttcg cttgatgatg
    11581 gatatgagtc aggagtcggg gaaacgtccg attatcggcc tttatctatc tttccttaca
    11641 gtggttgctg tgcacggaat ttttgacttg gctctcttct ggattcagtc aggctttatt
    11701 ttcttgctag ttatgtgcag tattccattg gagcatcgaa tgttggtatc ggacatgacg
    11761 gattaagttt tataagtttg aaatcttcta ccttgggtag gagatttttt tatacgatgg
    11821 gcatgtcgtg catctgaggt gtaagtcctc tgtagggatc cactaccggt gaatacaata
    11881 gcgctcccca agcctgacta tcgtgaggta gcggattaaa atggtctggg gatagatcgt
    11941 tttaagtctg acgcaggaaa taagaattgt cagagaaagc aatagtgaaa tcgtaggcta
    12001 tgaatagaaa cgtgatagcg aggagcatat agtggacaag gtagcgagaa attttaaagt
    12061 ataaaagata gtcttaatct atatgtgtaa atcacgaaag taattgaatt cggaataagg
    12121 ttggtgtgaa aagacatagt aaactgaatc ttgaatacta gaatgatact tctacaatat
    12181 tgttataatt taatttgaat tccaaaatca cattgttccg tccgtatttc attttactgt
    12241 atgtcttcct aagctccaaa atttctgtgt caaatttcct attttcactg tagtctttga
    12301 cacttcgaac gacaatttga atcatatatt caaaaaaaat gaaaaatttg tgccaacaag
    12361 cctaaatatt ctgaaaattt gtttgatttt taatggataa tgtgatataa tggttgtcaa
    12421 tctataattc acataaacag aggagtagaa aatgaaaaaa aatcgtgtat ttgctacagc
    12481 aggtcttgtt ttattagcag caggtgtact tgcagcatgc agttcttcaa aatcatctga
    12541 ttcatcagcc cctaaagctt atggctatgt ttatacagca gacccagaaa ccttggacta
    12601 cctgatttca agtaaaaata gtacaacagt agtgacttca aatgggattg atggtttatt
    12661 cactaacgat aattacggta atcttgctcc tgcagttgca gaggattggg aagtctctaa
    12721 ggatggtttg acctacactt ataagattcg taaaggggtt aaatggttta cctctgatgg
    12781 agaagaatat gcagaggtga cggctaaaga tttcgtgaac ggtttaaaac acgcagcaga
    12841 taaaaaatca gaagctatgt atttagctga aaattcggtt aaaggcttgg cagattatct
    12901 atcaggaact tcaacagatt tttcaacagt tggtgtcaag gcggttgatg attatacgtt
    12961 acaatacact ttgaaccagc ctgaaccgtt ctggaactct aagttgacct attctatttt
    13021 ctggcctctg aatgaagaat tcgaaacatc aaaaggaagc gattttgcta aaccaacaga
    13081 tccgacatcc ttgctttata atggtccatt cttgttgaaa gggttgactg caaaatcttc
    13141 tgtagagttt gtaaaaaatg agcaatattg ggataaagaa aatgtccacc tagatactat
    13201 caatctagct tactatgatg gatcagatca ggagtcgcta gagcgtaact tcactagtgg
    13261 agcttatagt tatgcccgtc tttaccctac cagctccaac tattctaagg ttgcagaaga
    13321 atacaaggac aatatctatt acacacaatc aggctctggg attgctggtc tgggtgtgaa
    13381 tattgatcgc caaagttaca actatacttc taaaactaca gattcagaga aagtagctac
    13441 taagaaggca ttgcttaaca aagatttccg tcaagccttg aattttgctc ttgatcgctc
    13501 agcttactca gctcaaatca atggtaaaga tggagcagct ttagcagttc gtaatttatt
    13561 tgtaaaacca gactttgttt cagctggtga gaagaccttt ggtgatttag tcgctgctca
    13621 acttcctgct tatggtgatg agtggaaagg tgtgaattta gctgatgggc aggatggttt
    13681 attcaatgct gacaaggcca aggcagagtt tgcgaaagct aagaaagctt tagaagcaga
    13741 cggcgttcag tttcctattc atctggacgt tccagtagac caagcatcaa aaaactatat
    13801 atctcgtatt cagtccttta aacaatctgt agaaacagtt cttggtgttg aaaatgtcgt
    13861 tgttgatatt caacaaatga caagtgatga attccttaat attacttact atgctgccaa
    13921 tgcttcatct gaggattggg atgtatcggg aggagtttca tgggggccag actatcaaga
    13981 cccatctact tacctggata ttttaaaaac aactagcagt gaaactacaa aaacatattt
    14041 aggatttgat aatccaaata gcccttcagt agttcaagtt ggtttgaaag aatacgataa
    14101 attagttgat gaagctgcca aagagacaag cgacttgaat gtccgttatg aaaaatatgc
    14161 agcggctcaa gcatggttga cagatagttc actctttatt cctgctatgg cttcttctgg
    14221 tgcagcacca gtgctttcac gaattgttcc atttactgga gcttctgcgc aaacaggctc
    14281 taaggggtca gatgtttact tcaaatattt gaaattacaa gataaagcgg tgactaagga
    14341 agagtatgaa aaagctcgtg aaaaatggtt gaaagaaaaa gctgaatcaa atgagaaagc
    14401 tcaaaaagaa ttggcaagtc atgtgaagta aataatttct aatagaactt tctctccatg
    14461 aggagaaggt tcttttggga tttttaaagg aaataatatg aaaaaatata tttttatgcg
    14521 tgttttgcgg tcattggttt cgattttctt agtaacgact ttgacctaca cgattatcta
    14581 taccttggtt cctcgaaaat tgattttcaa gcaggatcct aactataata aaattgcgac
    14641 aacggctgat aaacgtgata actatgaaaa tactgtgttt gagcgtatgg gctacattga
    14701 gtattacgat actaaagagt tgcaagaaaa ggcaagtagc atggattctt ctgtaacagt
    14761 agaagcaaat gcgaccaata aagctattta tgaaaagtac atcaatcaat taggtcatgg
    14821 ttggactttg ggagaattta ctgaaagtgg tcaattctat gctactcgtg aaattccaat
    14881 ttttgaacgt gtttttcact tctatgctaa cttgattgac attgaccata caaataaaat
    14941 ccaagaccct gaaaatccag acttgaaacg ctaccttcgt tttgaaaatg atccagctat
    15001 cggatggtca ttggtcggtt caggaactaa acataaatat ctcttgtact ttaacagtca
    15061 gttcccattt gttcatcaaa actttgtgaa cttgaattta ggtgactctt acccaaccta
    15121 tgctaataca ccagttcttc aggttattac tcaaggtcaa ggacaaacca aaactgccca
    15181 agttcagttc ccaacaggta agaaaacgtc ttctgtaaat atttactcaa gaacctacaa
    15241 gtcacctagt caggctgact ctcgtgaagt agctagctat gggaaagatg atccttatac
    15301 agcgactgaa agtaattacc aatatccatc tatgattgtc agctctgcta ttactggttt
    15361 gattggtttg gttcttgcct atgctcttgc cgtgccactt ggttcagcca tggctcgttt
    15421 caagaacact tggattgata gcctctcaac aggggctttg accttcttgc ttgctcttcc
    15481 aacgattgcc ttggtttaca tcgttcgatt gattggatca tctatttccc ttccagattc
    15541 attccctatc ttgggagctg gagattggcg ttcttacgtt ttaccagcag tcatccttgg
    15601 tttgttgggt gctcctggta cagccatttg gattcgtcgt tacatgattg acttgcaatc
    15661 tcaagacttt gttcgtttcg ctcgtgcaaa aggtttgtct gaaaaagaaa tttcaaacaa
    15721 acacatcttt aaaaatgcca tggttccgct ggtttcagga attcctggtg ccattattgg
    15781 ggttatcggt ggtgcaaccc ttactgaaac agtcttcgcc ttcccaggta tgggtaaaat
    15841 gttgattgac tctgtaaaag catctaataa ctctatggtc gttggtcttg tcttcatctt
    15901 tacatgtatt tctatcttct cacgtctttt gggagatatt tggatgacta ttattgaccc
    15961 acgtattaaa ttgactgaga aaggaggcaa ataatgtcta caatcgataa agaaaaattt
    16021 cagtttgtaa aacgtgacga ttttgcctct gaaactattg atgcgccagc atattcttac
    16081 tggaaatcag tgtttaaaca atttatgaag aaaaaatcaa ctgtagtcat gttgggaatc
    16141 ttggtagcca tcattttgat aagtttcatc tacccaatgt tttctaagtt tgatttcaat
    16201 gatgtcagca aggtaaacga ctttagtgtt cgttatatca agccaaatgc ggagcattgg
    16261 ttcggtactg acagtaacgg taaatcgctc tttgacggtg tctggttcgg agctcgtaac
    16321 tccatcctca tttctgtgat tgcgacagtg attaacttgg ttatcggtgt ttttgtcggt
    16381 ggtatttggg gtatttcaaa atcagttgac cgtgtcatga tggaagttta caacgtcatc
    16441 tcaaacatcc cacctctttt gattgttatt gtcttgactt actcaatcgg agctggattc
    16501 tggaatctga tttttgccat gagcgtaaca acatggattg gtattgcctt catgatccgt
    16561 gtgcaaatct tgcgctatcg tgacttggaa tacaacttgg cgtcacgtac tttgggaaca
    16621 ccaaccttga agattgttgc caaaaatatc atgcctcaat tggtatctgt tattgtgaca
    16681 accatgactc aaatgcttcc aagctttatc tcatacgaag ccttcttgtc tttcttcggt
    16741 cttggattac cgattacagt gccaagtttg ggtcgtttga tttcggatta ttcacaaaac
    16801 gtaacaacca atgcttactt gttctggatt ccattgacaa cccttgtctt ggtatccttg
    16861 tcccttttcg tagttggtca aaacttagcg gatgctagtg atccacgtac acatagatag
    16921 gagtagaaat gacaaaagaa aaaaatgtaa ttttgactgc tcgcgatatt gtcgtggaat
    16981 ttgacgttcg tgacaaagta ttgacagcca ttcgcggcgt ttcccttgaa ctagtcgaag
    17041 gagaagtatt agccttggta ggtgagtcag gatcaggtaa atctgttttg acaaagacct
    17101 tcacaggtat gctcgaagaa aatggtcgca ttgcccaagg tagtattgac taccgtggtc
    17161 aggacttgac agctttatct tctcacaagg attgggaaca aattcgtggt gctaagattg
    17221 cgactatctt ccaggaccca atgactagtt tggaccccat taaaacaatt ggtagtcaga
    17281 ttacagaagt tattgtaaaa caccaaggaa aaacagctaa agaagcgaaa gaattggcca
    17341 ttgactacat gaataaggtt ggcattccag acgcagatag acgttttaat gaatacccat
    17401 tccaatattc tggaggaatg cgtcaacgta tcgttattgc gattgccctt gcctgccgac
    17461 ctgatgtctt gatctgtgat gagccaacaa ctgccttgga tgtaactatt caagctcaga
    17521 ttattgattt gctaaaatct ttacaaaacg agtatcattt cacaacaatc tttattaccc
    17581 acgaccttgg tgtggtggca agtattgcgg ataaggtagc ggttatgtat gcaggagaaa
    17641 tcgttgagta tggaacggtt gaggaagtct tctatgaccc tcgccatcca tatacatgga
    17701 gtctcttgtc tagcttgcct cagcttgctg atgataaagg ggatctttac tcaatcccag
    17761 gaacacctcc gtcactttat actgacctga aaggggatgc ttttgccttg cgttctgact
    17821 acgcaatgca gattgacttc gaacaaaaag ctcctcaatt ctcagtatca gagacacatt
    17881 gggctaaaac ttggcttctt catgaggatg ctccaaaagt agaaaaacca gctgtgattg
    17941 caaatctcca tgataagatc cgtgaaaaaa tgggatttgc ccatctggct gactaggagg
    18001 aaggaaatgt ctgaaaaatt agtagaaatc aaagatttag aaatttcctt cggtgaagga
    18061 agtaagaagt ttgtcgcggt taaaaatgct aacttcttta tcaacaaggg agaaactttc
    18121 tcgcttgtag gtgagtccgg tagtgggaaa acaactattg gtcgtgctat catcggtcta
    18181 aatgatacaa gtaatggaga tatcattttt gatggtcaaa agattaatgg taagaaatcg
    18241 cgtgaacaag ctgcggaatt gattcgtcga atccagatga ttttccaaga ccctgccgca
    18301 agtttgaatg aacgtgcgac tgttgattat attatttctg aaggtcttta caatcaccgt
    18361 ttatttaagg atgaagaaga acgtaaagag aaagttcaaa atattatccg tgaagtaggt
    18421 cttcttgctg agcacttgac tcgttaccct catgaattct caggcggtca acgtcaacgt
    18481 atcggtattg cccgtgcctt ggtcatgcaa ccagactttg ttattgcaga tgagccaatt
    18541 tcagccttgg acgtttctgt acgtgcccaa gtcttgaact tgctcaaaaa attccaaaaa
    18601 gagctcggcc tgacctatct cttcatcgcc catgacttgt cggttgttcg ctttatttca
    18661 gatcgtatcg cagttattta caagggtgtt attgtagagg ttgcagaaac agaagaattg
    18721 tttaacaatc caattcaccc atatactcaa gccttgcttt cagcggtacc aatcccagat
    18781 ccaatcttgg aacgtaagaa ggtcttgaag gtttacgacc caagtcaaca cgactatgag
    18841 actgataagc catctatggt agaaatccgt ccaggtcact atgtttgggc gaaccaagcc
    18901 gaattggcac gttatcaaaa aggactaaac tagtaatggt tttataattt ccatgtcaat
    18961 ttttatggaa attataaaac tttttttgtt ggactgattt gaaaaacttt gaaagcttcc
    19021 tgaaagaatt tttgaaaaat tttaaaaatt atgaaatgtt attgacaggt gatgaaaaag
    19081 gtggtaggac aggaagcatc aaaaaagaaa gcagaaaaag aaatgaataa gagacaagcc
    19141 gtaactatga atcaaaactt ttactttagc tactttagat agtgtttgta gacatgtcac
    19201 catggatgca aacagttcaa gcaatttgtt tgtatctatg tggctaagat ttttgattgt
    19261 ggtccatata gatgaatatc taaatggact agctaagttg taacttgtta ggttatttca
    19321 agtatccgtt tagatagtat ctaggcggtt ttttgtttta tcttttctga gaaggagttt
    19381 cattatgaaa gttgttcgaa aatcactagc cccctcttgg tagtggggct cctcttgact
    19441 tctctgatca gtttgcatca gttgaaggca gataagaaaa agatgtcttt cgtatcggta
    19501 tttcgcaatt tattacccac cagtccttat acgctactag agaaggattt gtggataagc
    19561 tggccaaaca aggctatgtt gagggggaaa atattgagat tgatttgcaa aatgcacagg
    19621 gagaacaaag aaatctaaaa acgatttccc agcaactagc agaatccagc gatgtcgttc
    19681 tagccatcgc aaggccttct gctcagagct tggccaatac gacgcaaacg acaccagtta
    19741 tcttttcagc tgtaacagac ccagtcagtg ccaagttggt tgagtcaaga gaacatcctg
    19801 ggggcaatgt aactgggaca agcgatcagt catcagatgc catttcaacc caaatcaatt
    19861 tgataaagaa agtgttgcca aaggctaaaa cgattggaat cctctatact cagagcgagc
    19921 ccaattcggt tgttcaaaag gatgaagcta agcgacttct gaaagaaaaa ggctttaccg
    19981 ttgttgaaaa aacaatcttg gacagtaata acgtcaaggc ggcagcagag agtttgatgg
    20041 cagaggtgga tatggttttt gtcccaactg ataatatcat ttcgttaacc atggaaacag
    20101 ttaagcaggt ttctattaaa cacaaggttc cagtattcgg tggttcaaca gaaatgattg
    20161 ctgttggtgg cttgtataac tacggaacca attatgaaga attgggacgt cagacagctc
    20221 gcatgctgat tcgtgtttta aaaggtgaga aaccagaaaa tatagcagtt gagttgcctg
    20281 aaaaactgga attgcatacc aatcaagaaa tggcagatgc attgggaatt gatattagta
    20341 agttagaagg caaggaataa ggaggattaa gatgaatttt gtgttatcta gtttatcaga
    20401 aggtttgttg tggtcgattg tggcgattgg ggtctacttg actttccgta ttttggatat
    20461 tgcggatatg actgctgagg gagcctttcc tctgggggca gcagtcgttg tatcacagat
    20521 acaggcaggg gcaaatcctt ggcttgcgac tttacttgct ttgctggcag gtatggtagc
    20581 aggtcttgta tcaggaatgc tccacaccaa gatgaaaatc ccagctctct tgacagggat
    20641 tgtgaccttg acagggctct attcaatcaa tattaaaatc atgggcagtg tacccaatct
    20701 ttccttggga gattctgcaa ccgtctttaa acagttggcg agcttgggtc tgacaaatga
    20761 aggaactgtt ttctcactta gtttggcctg ttttttactt gtttgtttgg tcttgaccct
    20821 tttgatgaaa acagagattg gcttggtctt gcgttcgact ggggataata tcccgatgag
    20881 tgaggccaat ggagtcaatg tagacaccat gaagattgtt ggttacatga tttcaaacgg
    20941 tttgattgct ctatgtggtt ccttgtttgc ccaaaatgat ggattttcag atgtgacttc
    21001 tgggacagga accattgttg ttggtttgag ctcggtgatt attgcggaag tcttgataca
    21061 cgacttgacc attggaggcc gcttattatc catcggaatc ggtgctattg tttaccgttt
    21121 gattatttta aatatctatg aaattccaaa tctagatcaa aacttggtac gtctctttaa
    21181 tgcaatcttg ctcgctttgg ttttatttgc accagaattg caaaagagat taaagattcg
    21241 tggtctgaaa ttgagaaatg aataggagga gaaagttatg acaagtttgt taacacttga
    21301 aaatattcac aagacatttg aagcagggac ggtcaatgag aaccatgtcc tcaaaggatt
    21361 agatttagag gttgaagagg gagattttat ctctgtgatt ggtggaaatg gagcaggaaa
    21421 atccactttg atgaatatct tggctggcaa tctatcggtg gacgaagggg accttctact
    21481 ggcagggaaa tccattaaaa atctgagtgt cagaaagaga gccaaggata ttgcccgtgt
    21541 ttttcaagat cctaagatgg gaacagcttc tcgtttgacg attgaggaga atatggctat
    21601 tgccttgaga cgcgggcaga agagagggct tggttggggc gtgaaggaga aggatagaat
    21661 ccagttccaa gaggccttga aggagttgaa tattggtctt gaaaaccgct taaaagtaga
    21721 tactcaatat ctctcaggag gacaaagaca ggctttgact ctagtcatga cagatctgat
    21781 gaaaccaaaa cttttacttt tggatgaaca tactgcggca cttgacccga aaaccagtca
    21841 aatggtgatg aacttgacgc aaaagattgt ggagcaccat cagtggacga ctttgatgat
    21901 tacccatgat atgaatcatg cgattgagta cggcaatcgt ctcattatgc tctatcaagg
    21961 caagatagtg gtggatgtca agggagaaga gaaaaagcat ctgacagttg aagaccttat
    22021 gcatctcttc cagaaaaata gtggccaaag tctggtcagt gatgaattag ttttgggata
    22081 aagaaaaagg ctgagatctg gtgtctcagt cttttatttc ttgcgttttg caaaatctac
    22141 aaatctaaat ttctctaact tatggcgact ttcggtaaac tgaaattggc gtccgtcttg
    22201 gagatagact tttgatttaa tcgaaacgac ataagggtct ttgccaatgt ccatgagaat
    22261 cttgtctcgg tcgcttgagt ggtcaatggt gatttccttc tgagcataat caataaggag
    22321 tttgaggcca ttttctatat aagaatagat agactgctca gcaatttggc gagtgagatt
    22381 tggaattagt tccatatcca gatagtccgt atccagaacg gataccagat catccaccac
    22441 acgctggcgg accaccttcc aaaccatccg aaactctggg aaaccggtta tcagtgagga
    22501 ttttttatca ataataatct tgtccagact gaccacgttg gttttagagc gcagtccaag
    22561 ttctttaact agttcttggt agctggttag gttggataca gggaaattga cggtttcttc
    22621 tttgacgact tgagaacctt gccctcttat ctttttgatc aatccttcct cttggaggag
    22681 agacagggcc tttcggacgg tatcacgact cacttgatat tgctccataa ggtcgtgctc
    22741 gctaggaagg aaatctccga cagcgtaagt ctcgttttga atggtttctt ggatttgctt
    22801 aaataattgt tggtatttct tcattttgcc tgcttaaata ggtttttagt ctagtttaat
    22861 gaacacctgt atctatttta ccatacaagt gctagaaaat ttacaaaaaa acaccctttt
    22921 tataccaaac aagttgcaga caagtttggt atcgtttaca atatacttat caaatcaaac
    22981 ttgctttgac aagtataagg agaatcaaat gggaaaattt gaacaagaag ccaaagatct
    23041 gcttcaggca atcggaggca aagaaaatgt gactgccgta actcactgtg cgacacggat
    23101 gcggtttgtt ttaggagatg ataagaaggc taatgttaaa gctatcgagt caattccagc
    23161 tgttaaagga acctttacaa atgcaggtca atttcaggta atcattggaa atgacgtgcc
    23221 catcttttat aatgatttta cagccgtttc aggtattgag ggtgtttcca aagaagcagc
    23281 caagtctgca gctaagagta atcaaaacgt ggtccaacgt gttatgacca ctctggcgga
    23341 aatctttact ccgattattc cagccttgat tgttggtgga ttgatcctcg gtttccgtaa
    23401 tgtcttggaa ggtgtccatt ggtcgatgtt ggatggcaag accatcacag aatcctctca
    23461 gttttgggca ggggttaatc acttcctctg gttgcctggt gaagctatct tccagttctt
    23521 accagtaggg attacttggt ctgtttctcg taagatggga accagccaaa ttttgggaat
    23581 tgttctcgga atctgtttgg tatcgcctca gttgctcaat gcctatgcgg ttgcttcaac
    23641 gccagcagct gatatcgcgg caaactgggt ttggaatttt ggctatttta ctgttaatcg
    23701 tatcggttac caagcccaag ttatcccagc cttgcttgca ggtttgagtc tgtcttatct
    23761 tgaaatcttc tggcgcaagc atatcccaga agtcatttct atgatttttg tacctttctt
    23821 gtcattgatt ccagccttga ttttggctca tactgttttg ggaccaatcg gttggacaat
    23881 tggacaagga ctttcatcag ttgtcttggc aggtttaact ggtccagtta aatggctctt
    23941 cggtgcaatt tttggtgccc tctacgctcc atttgtcatc acaggtctgc accatatgac
    24001 caatgccatt gatacacaat tgattgcgga tgctggtggc actgccctat ggccaatgat
    24061 tgctctttct aatattgctc aaggctcagc cgtgtttgcc tattatttca tgcatcgcca
    24121 tgatgagcgt gaggctcagg tttcacttcc tgcaaccatt tcagcctatc tcggtgttac
    24181 agaaccagct ctttttgggg ttaacgtaaa atatatttat ccatttgttg ctgggatgac
    24241 tggttcagcc cttgcaggca tgttatccgt tacttttaat gtaactgcgg cttctattgg
    24301 tatcggtggt ttgccaggta ttctctctat tcaacctcaa tacatgctgc catttgcagg
    24361 aactatgcta gttgcgattg ttgttccaat gctcttgact ttcttcttcc gcaaggctgg
    24421 tctctttaca aaaacagagg gcgatacgaa cttgcaggca gaattcgttg ctcaagaaga
    24481 agcagaattt gtgaaccatg aaccagtaga acttacttcg gtagaaatta tcagcccact
    24541 aactggccaa gtgaaagaat tgagtcaagc gacgaatcct atttttgcat caggtgtcat
    24601 ggggcaaggt ctggtcattg aaccaagcca aggtgagttg acctctccag ttaatgggac
    24661 agtgacggtt cttttcccta ccaagcatgc catcggcatt gtctctgacg agggagttga
    24721 attgctcatc cacatcggta tggatacagt aggtcttgat ggcaaaggtt ttgaaagtct
    24781 tgtagtccaa ggagatcacg ttacagttgg tcagcaactg attcgttttg atatggatgt
    24841 cattaaggct gcaggtctgg tgacagaaac tcctgttatc atcaccaacc aagatgctta
    24901 tacagcgact attcctggaa cttatccgac aacgatccaa gctggagcat ctctcatggt
    24961 cgctacacga atctaatact cttcgaaaat ctcttcaaac cacgtcagct ctatctgcaa
    25021 cctcaaaata gtgttttgag caacctgtgg ctagcttcct agtttgttct ttgattttca
    25081 ttgagtataa ttgaaatagc acaaataggg acggaagact gcttcctccc ttttatcaga
    25141 aaaggagaaa cagatgacac ttgataaagg aaaagtagtc tatcaaatct atccaaaatc
    25201 ttacaaagac accactgaaa acggtattgg ggatttccgt gggattatcg aaaaaattcc
    25261 ctatttagcc aaactaggtg tggatatggt ctggctcaat ccattctatc caagccctca
    25321 acgggataat ggttacgata tttcagatta tatggcagtg gatcctcttt ttggtgatat
    25381 ggctgatttt gaggaaatgg tgtgtgtcgg taaagagcac aagattgact ttatgctgga
    25441 catggtactt aatcattgtt cgacagagca tgaatggttt cagaaagccc tagctggtga
    25501 taagtattat caagactttt tcttcatcca agaccaacca acagattggc agtctaagtt
    25561 tggtggttct gcatgggcgc ctttcgggga tactgggaaa tactatcttc acctatttga
    25621 tgagacccag gctgacctta actggcgcaa ttccaatgtc cgtaaggagc ttttcaaggt
    25681 tgttaatttc tggcgcgaca agggtgtcaa aggtttccga tttgatgtga tcaatttgat
    25741 cggtaaggac gaggtttcag tggactgtcc tgaaaatgaa gggaagccag cttatacaga
    25801 caaacccatc gttcataact atttgcgtat gatgaaccaa gccacttttg gatctgacga
    25861 tagctttatg acagttgggg aaatgtcttc taccaccatg gaaaactgtg tcctctattc
    25921 gtcgcctgat cgtcaggaat tatccatgac ctttaatttt catcacctca aggtggacta
    25981 taaggatgga caaaagtgga ccttggctcc ctttgatttt gaagagttga agagtcttta
    26041 ccatagttgg ggtaaggaaa tgagtgataa agacggttgg agtgccctct tttggaacaa
    26101 tcacgatcaa ccacgtgcct tgaaccgttt tgtcgatatt caaaacttcc gcaaggaagg
    26161 agccaccatg ctagcagcca gcattcacct gtcacgtggg acaccttata tctacatggg
    26221 tgaggaaatc gggatgattg acccagacta tgattctatg actgattatg tggatgtcga
    26281 atcgcttaat gcctatcaga tgctcttaga agaaggaaag agtcagcaag aagccttcca
    26341 gattattcaa gctaagtcgc gtgataattc acgtattccc atgcagtggg atacttctga
    26401 aaatgcagga ttttcaacag gcactccatg gttgaaagtt ggtaaatcct ataaagatat
    26461 caatgtagaa aatgaaatca aaggtctgat tttcaccttc tatcaagact tgattcgact
    26521 gcgtaaggaa atgccaatca tttcagaagg aaattacaaa ccagcctttg aagatagcaa
    26581 acaagtctac gcttttgaac gccagtttga ggatcaaaag ttactagtgc tcaataactt
    26641 ttatgccaaa gaagtggaaa tcgacttgcc agcagtctac caaaatggac agattttgat
    26701 ttcaaactat gaagatgcag aagtgtctga gaaaattcta ctcaaaccct atcaaacact
    26761 ggctatttat gtaaattaat actcttcgaa aatctcttca aaccgtgtca gttttatctg
    26821 taacctcaaa gcggtgcttt gagcaacctg tggctagctt cctagtttgc tctttgattt
    26881 tcattgagta taaacttagc aaggagacct ctttttcaga aaagcagggt tctttttgct
    26941 gtctattcca tccttgaaag tgtagaacaa actggtcagg gtggctagtt tgtggtataa
    27001 tgaaagggac tcaaaaagaa acaggagaaa aatgatggat ttacttttag caattgtatt
    27061 gattgtgcta gcttttctag gaggagctct tggaggaatg tacttggttc gtaagcaaat
    27121 cgaaaaagaa tttgctgaca acccacgttt gaatgctgaa gcagttcgta ctcttttgag
    27181 tgcaaatggt caaaaaccaa gcgaagctaa ggtacaacaa gtttaccacc aaatcatccg
    27241 ccaacaaaag gcagcccttg ctaacaataa aaagaaaaaa taaataagga aaagtctggg
    27301 atgaaagttc cagacttctc actatgttgg ttatggttta gggatgagac tttttccttg
    27361 cattctattg atatttgatt atgattaaga gagaggtagt tgacattcta tcaagctgtc
    27421 ggtcagttcg ttcagtacaa ggaatcataa tgaacgatca atcagaaaaa agactagaaa
    27481 gaagactgta tggataatcg accaattggt tttttggatt cgggtgtcgg gggcttgacc
    27541 gttgtgcgcg agctcatgcg ccagcttccc catgaagaaa tcgtctatat tggagattcg
    27601 gcgcgggcgc cctatggccc ccgtcctgct gagcaaattc gtgaatatac ttggcagctg
    27661 gtcaactttc tcttgaccaa ggatgtcaaa atgattgtca ttgcttgtaa cactgcgact
    27721 gcggtcgtct gggaagaaat caaggctcaa ctagatattc ctgtcttggg tgtaattttg
    27781 ccaggagctt cggcagccat caagtccagt caaggtggga aaataggagt gattggaacg
    27841 cccatgacgg tacaatcaga catataccgt cagaaaatcc atgatctgga tcccgactta
    27901 caggtggaga gcttggcctg tcccaagttt gctcccttgg ttgagtcagg tgccctgtca
    27961 accagtgtta ccaagaaggt ggtctatgaa accctgcgtc ccttggttgg aaaggtggat
    28021 agcctgattt tgggctgtac tcattatcca ctccttcgcc ctattatcca aaatgtgatg
    28081 gggccaaagg ttcagctcat cgatagtggg gcagagtgcg tacgggatat ctcagtctta
    28141 ctcaattatt ttgaaatcaa tcgtggtcgc gatgctggac cactccatca ccgtttttac
    28201 acaacagcca gtagccaaag ttttgcacaa attggtgaag aatggctgga aaaagagatt
    28261 catgtggagc atgtagaatt atgacaaata aaatttatga atataaggat gaccgggact
    28321 ggtatgttgg gtcttatagt atttttggtg gcgttaacag tttgagcgac tataagacag
    28381 attttcctct gtttgaattc tccaaaatat ttggagatga agagtatggt ttcccgcttt
    28441 cagttactgt tttacgctat ggttctacct accgtttgtt ctcctttgtg gtagacatgc
    28501 ttaatcaaga aatgggacga aacttggaag ttattcaacg tcatggggcc ctgctcttgg
    28561 ttgaaaatgg gcaactcttg tatgtagaat tgcctaaaga aggggtcaat gttcatgatt
    28621 tctttgagac aagcaaggtc agagaaacct tgttgattgc gactcgtaac gaaggtaaaa
    28681 ccaaggaatt ccgagctatc tttgataagt taggctacga tgtggaaaat cttaatgact
    28741 accctgacct gcctgaagta gcagaaacag gtatgacctt tgaagaaaat gcccgcctta
    28801 aggcagaaac catttctcaa ttaacgggca agatggtttt ggcagatgat tctggtctca
    28861 aagtcgatgt ccttggtggc ttaccaggcg tctggtcagc tcgtttcgca ggtgtgggag
    28921 caactgaccg tgaaaataat gccaaactct tgcacgaatt ggccatggtc tttgaactca
    28981 aggaccgctc ggctcagttc cacacaaccc tagtcgtagc cagcccaaat aaggaaagtt
    29041 tagttgttga agcagactgg tcaggttata ttaactttga acctaagggt gaaaatggct
    29101 ttggctatga tcccctcttc cttgtaggag agacaggtga gtcatcagct gaattaaccc
    29161 tggaagaaaa aaatagtcaa tctcaccgtg ccttagccgt taagaaactt ttggaggtat
    29221 ttccatcatg gcaaagcaaa ccatcattgt aatgagcgat tcccatggcg atagcttgat
    29281 tgtggaagaa gtccgtgatc gctatgtggg caaagtcgat gccgtttttc ataacggcga
    29341 ttctgaacta cgtccggatt ctccactttg ggagggcatc cgcgttgtta aagggaacat
    29401 ggacttctac gccggctacc cagaacgtct ggtgactgag cttggttcga ccaagattat
    29461 ccaaactcat ggtcacttgt ttgacatcaa tttcaacttt caaaagttgg actactgggc
    29521 tcaggaggaa gaggccgcta tctgcctcta tggtcacttg catgtgccaa gtgcttggat
    29581 ggaaggcaag atcctctttc taaatccagg ttctatcagc caaccacgag gtaccatcag
    29641 agaatgtctc tatgctcgtg tggagattga tgatagttac ttcaaagtgg actttttgac
    29701 acgagatcac gaggtgtatc caggtttgtc caaggagttt agccgatgat tgccaaggag
    29761 tttgagactt tcttgttggg gcaggaggaa acttttttga cccctgctaa aaatctagct
    29821 gtgttgattg atacccacaa tgcggatcat gcgaccctct tgctcagtca gatgacctat
    29881 acccgtgttc ccgttgtgac agatgaaaaa cagtttgttg ggacgattgg actcagagat
    29941 attatggcct atcagatgga gcatgacttg agccaagaaa tcatggcgga tacggatatc
    30001 gttcatatga caaaaacgga cgtagcggtt gtttcgcctg atttcaccat tacggaggtc
    30061 ttgcacaagc tagtagatga gtccttctta ccggttgtgg atgcagaggg tattttccaa
    30121 gggattatta cgcgcaagtc catcctcaag gccgttaatg ccctcttgca tgactttagt
    30181 aaggaatatg agattcgatg ccaatgagag acaggatttc agccttttta gaggaaaagc
    30241 agggcttgtc tgtcaattcc aagcagtcct ataagtatga tttggagcaa tttttagaca
    30301 tggtaggtga gcggatttct gagaccagtc tcaagattta ccaagcccag ctagccaatc
    30361 taaaaatcag cgcccagaag cgaaagattt cggcctgtaa ccaatttcta tactttctct
    30421 atcaaaaagg agaggtggac agcttttacc gcttggaatt agccaaacaa gctgaaaaga
    30481 agacggaaaa gccagagatt ctatacctag actctttttg gcaggaaagc gaccatccag
    30541 agggccgctt gctagcgctc ttaatcctag aaatggggct tttgcccagt gagattttag
    30601 ccatcaaggt tgcggacatc aatctggatt ttcaggtgtt gcgaatcagc aaggcttccc
    30661 aacagaggat tgtcaccatt cccacggcct tgctttcaga attggaaccc ttgatggggc
    30721 agacctatct ttttgaaaga ggagagaaac cctattctcg tcagtgggcc tttcgtcagt
    30781 tagaatcttt tgtcaaggag aaaggttttc catccttatc agctcaagtc ttacgtgaac
    30841 agtttattct aagacaaata gaaaacaagg tcgatttgta cgaaattgca aaaaaattag
    30901 gattaaaaac agtcctgacc ttagaaaaat atagataatg gatattaaat taaaagattt
    30961 tgaaggaccc ctggacttgc tcttgcatct ggtttctaag taccagatgg atatctacga
    31021 tgtgcccatt acggaagtca tcgaacagta tctagcctat gtctcaaccc tgcaggccat
    31081 gcgtctggaa gtgacgggtg agtacatggt catggctagt cagctcatgc tgattaagag
    31141 tcgtaaactc cttccgaagg tagcagaagt gacagacttg ggggatgacc tggagcagga
    31201 cctcctctct caaatcgaag aatatcgcaa gttcaagctc ttgggtgagc acttggaagc
    31261 caagcaccaa gaacgggccc agtattattc caaagcgccg acagagttga tttacgaaga
    31321 tgcggagctt gtgcatgaca agacgaccat tgacctcttt ttggcttttt caaatatcct
    31381 agccaagaaa aaagaggagt ttgcacaaaa tcacacgacg atcttgcggg atgagtataa
    31441 gattgaggac atgatgatta tcgtgaaaga gtccttgatt ggacgagatc aattgcgctt
    31501 gcaggatttg ttcaaggaag cccagaatgt ccaagaggtc atcaccctct ttttggcaac
    31561 cctagagtta atcaaaaccc aggagctgat cctcgtgcaa gaggagagtt tcggagatat
    31621 ctatctcatg gaaaagaagg aagaaagtca agtgcctcaa agctagactt gatagagagg
    31681 aaagatgagt actttagcaa aaatagaagc gctcttgttt gtagcgggtg aagatgggat
    31741 tcgggtccgc cagttagctg aactcctctc tctgccaccg acaggcatcc agcaaagttt
    31801 aggaaaatta gcccagaagt atgaaaagga cccagattcc agtttggctt tgattgagac
    31861 aagtggtgct tatagattgg tgaccaagcc tcaatttgca gagattttga aggaatactc
    31921 taaggcgcct atcaaccaga gcttgtctcg ggctgccctt gagaccttgt ccattattgc
    31981 ctacaaacag ccgattacgc ggatagaaat tgatgccatc cgtggagtta actcgagtgg
    32041 agccttggca aagttgcagg cttttgacct gataaaggaa gacgggaaaa aggaagtatt
    32101 ggggcgcccc aacctctatg tgactacgga ttatttccta gattacatgg ggataaacca
    32161 tttagaagaa ttaccagtga ttgatgagct tgagattcaa gcccaagaaa gccaattatt
    32221 tggtgaaagg atagaagaag atgagaatca ataagtatat tgcccacgca ggtgtggcca
    32281 gtaggagaaa agcagaagag ctgattaagc aaggcttggt gacggttaac ggccaagtgg
    32341 tgcgtgaact agcaaccact atcaagtcag gcgacaaggt cgaagttgaa ggtcaaccta
    32401 tctacaacga agaaaaggtc tactatctgc ttaacaaacc acgcggtgtg atttccagtg
    32461 tgacagatga taagggtcgc aagacggttg tcgacctctt gcccaatgtc aaagagcgta
    32521 tttaccctgt gggtcgtttg gactgggata catcaggtgt cttgattttg accaatgatg
    32581 gggactttac agacgagatg attcaccctc gtaatgagat tgacaaggtt tatgtcgcgc
    32641 gtgttaaagg tgtggtcaat aaggacaatc tccgcccctt gacccgtggt cttgagattg
    32701 atggtaagaa aaccaagcca gctgtttatg aaattctcaa agtggaccca gtcaaaaatc
    32761 gctctgtggt gcagttgacc atccatgaag ggcgtaacca tcaggttaaa aagatgtttg
    32821 aagctgttgg tctccaagta gataagttgt ctcggactcg tttcggacac ctagacttga
    32881 caggactccg tccaggagaa tcccgtcgtc ttaataaaaa agaaatcagc caactacaca
    32941 ccatggctgt aactaagaaa taatgaaacg aattttaata gcgcctgtgc gcttttacca
    33001 acgttttatc tcaccagtct ttccaccctc ttgtcgcttt gagctgactt gttccaacta
    33061 catgattcag gctattgaaa aacatggttt taagggggta ttgatgggct tggctcggat
    33121 tttacgttgt catccctggt cgaaaacagg taaggacccc gttccagacc gcttttccct
    33181 taaacgaaat caagaagggg aatgaggtgg ggtaaataga tttcaaaatg ataaaaacgc
    33241 atcctatcag gtttgagtga acttgatagg atgcgtttta gaatgtcaaa attttatact
    33301 cttcgaaaat ctcttcaaac cgcgtcagct ttcatctgca acctcaaaac agtgttttga
    33361 gcaacctgcg gctagttttc tagtttgctc tttgattttc attgagtatt aaattgagtt
    33421 tgaagtggct tatttcaaag ctttttgtat gtcttcaatc atgagttttg ttgattcaag
    33481 tccgcctccg cttagatacc agaggtctgg tgttagttgg ataatcttac catttttagc
    33541 agcaggtgtt tcagcgataa gggcattttc taggacaccg tcgttgctag agttgtcccc
    33601 accgatggca agggtacggt tgatgacaaa gaggatgtca gggttgattt ctttgacact
    33661 ttcaaagctg acttcttgtc cgtggcgtga gtcttcaaat tttgtatcag ttggtttgaa
    33721 tttcaaggtt tggtacaaga aagagaaacg agatttggca ccaaaggctg ccatttttcc
    33781 ttcattaagg aggatcgcaa gggctttttt gtcagagctt tcatttttag tagcgacttc
    33841 ttggatgctc ttgtctagct tggccaattc ttccttggct ttctgtgtac cagtttcgcc
    33901 gaaggcactt gctaaggatt cgatattagc cttggtagaa gtccagtagt cgtccttgct
    33961 tgcttggaag agaacggttg gggcgatttc tttgaatttg tctacgaatt tttgtgtacg
    34021 tggtgaagcg ataatcaaat caggctcaag ggcggcgata gcttctaaat caggttcttt
    34081 catagaacca acatttttga cagttcccac taggtctttt agataagtcg gaacagtttt
    34141 tgtaggcatt ccgacgatat ttttttcaaa tcctaaagcg cgaatagtat ccgcagcgcc
    34201 gaggtcaaag gtcacaatct tttcaggaac tttggaaagt ttgacctcgt ccagtgaact
    34261 tttaatggtt acctctgttg gagcagagct actggtctct gtctgactag tgcttgagtt
    34321 tgtactacat gcaccaagta ggagcaagaa gctggccact agggcagtga aataaagttt
    34381 aagggatgtt ttcataattt ctccttttta aaatgtgata acgatttagg gagtctctta
    34441 atcttattga ctaagagact gaaggttctc taacttgagc ttttatgtta ctagctatag
    34501 atacagatct ttttgttatt gatatcagct agcgtgatgg gaatctcata aagttgactg
    34561 agcaggtcag cctgcatgat ttgatcggtt cttcccttgc taaagacctg gccgtccttg
    34621 aaggcgacaa tttcatctgc atactgactg gccatgttga tatcgtggag gacgatgata
    34681 atggtcttgc cgagttcctc caccagtcgt cgaagaatct gcatcatgct gacgctttgc
    34741 ttgatatcga gattgttgag tggttcgtcc agcaagataa agtccgtatc ctgggccagt
    34801 accatagcga taaagacgcg ctggagttgc ccccctgaca ggctattgat gtagcggtct
    34861 tttaagttgg tcagttccaa atagttcaga gtttctcgga ttttttccca gtcttctgat
    34921 ctaagtcgac ctcggctgta gggaaaacgt ccaaaactga ccagttcttc aacagtcaat
    34981 ttggcttggt aattgatttt ctgttttagg atggttagtt cttgagccag ttcttgcgaa
    35041 ttccagctct cgatttcacg tcctttgata ctgagaactc cctgatcttt cttggttagt
    35101 ctgctcatga tggagaggag agtcgatttt ccagcaccat ttggaccaat aaaggctgtc
    35161 agtttttgag gactgacttc aagcgaaatg ccttgcaaaa tatcctgttt ttgaatggat
    35221 ttgtcaatgt tttccagttt cactgacgag acctcctata tagtaagata aagaataaga
    35281 agccacccac actctcaatg atcatactga tacgaatttc cagtgcaaag actcgttcaa
    35341 tcaaggcttg ccccaaggtt aagctaataa atccaaccag aatggccact ataaagagta
    35401 acttgtgctg atagtctttg acaatcaggt aggtgaggtt ggccagcata aagccgaaga
    35461 aggccatagg tcctaccaag gcagtggccg ttgaggtcaa aagcacgatt ccccagagga
    35521 gctctttctg ttctttttca acatcgagtc ccaatatctg agccgtttct ctttgcaggt
    35581 gcaagacatc tagaacgact gcttttcgaa agaaaaagat tgtcaaagcg aggatgatca
    35641 gagaaccgat ggctaggatg gaagtgttaa gatgttgaaa ggaggcaaaa agactatttt
    35701 gcagtttatc gtattcgttt ggatccatta ggacttgaag gaaggtgctg atatttcgaa
    35761 agagacttct gagcgctaga cagatcagca ggatgaagac caggtcttgc ttcatcagtg
    35821 tcttcaagta accttgtaag gcgagaaaga agaaggactg gacaagaagt aagactagga
    35881 attctaagat aggggatttg ccaagttgaa gaaacttgct ttcaaaaacc agtagtaggg
    35941 tttgtagtag gacgtagaag gattcaattc ccaaaatact aggcgtcagg aagcgatttt
    36001 ccgtcagggt ttgaaaacta atggtcgaaa tcccagtcgc gatggctacc aagagataaa
    36061 cgatgatctt ttgggaacgc aacttccaag caaaggctga caagtgagtg atgggccaaa
    36121 agtagagaag acaagctccg atggcaagaa taatgagaat ccagaagagc ttggtatgtt
    36181 tgcttttagt ctgcatcttt tcgtccccct ctccagagaa gtaggataaa gacgagacta
    36241 ccgatgattc ctagcaagag actgacagac aactcatagg gcctaatcag aactcgggat
    36301 aggatatcgc aagccagaac tagattggca ccaaccagtg cgaccatgag tttggtttga
    36361 cttagattat ctccatagcg cttgcgaaca agattgggaa cgataactcc gagaaatggt
    36421 aagccaccca cggtaatcat ggtgacgctt gtcgttagcg ccaccagaaa gagggccagt
    36481 ttttcaagta gggagtagga aatccccaaa ctctcgctgg tttctttccc cagattcatg
    36541 atggtgaagg tttgggataa tttccaaacg gttatcagga tgatgaggcc taagaagagc
    36601 cactcatact gatgggtctg aatcatggag aaggagccct gggtccaggc agtcatactc
    36661 tgaaccagat tgaaacgata ggcgataact tctgtgactg agccgataat cccgctatag
    36721 atgatcccaa tcagaggcaa catccacctt tcctttacag taaaaatggt cataaaggct
    36781 aggaagaaga gggtgaatac gatggatgaa acaaaagcga agagcatctt ttgggtcaga
    36841 ctagccgatg gaaagacaaa aaggctcagc accattccca gtttggcggc ttcagtcgtt
    36901 ccaactgtac tcggtgcagc aaactgattt tgggtaatag tctgcatgag aaggcctgcc
    36961 atactcatac tagaggcagt caggagaata ctgatagttc ttgggagacg ggactcttga
    37021 aagaggagcc aggtctgctg gtcgaaatca aatagctttc cccatgaaaa atcactggtc
    37081 ccaatgctaa tagagagaaa gactaggagt agaagtaagc caattaaata atgagaaagt
    37141 ttcatacccc gtcctttcat gtagatttgg tatcgaaaga tatctgcgga tataaatgta
    37201 acattatttt tctaatctgt caataaaatt tctgataatt taataaatac aacaaggaga
    37261 gagcaacaag actttctcct ttgttatcct attctaaaat gtttttacct taatctgata
    37321 aaataatatc ttcgagggag tagctagccg tccaatcaag atattgttta gcttttgaag
    37381 catctgctag gacactggct gggtcactag cacgtcgagc aacaatctcg tgtgggattt
    37441 tttaatttag taattcttca gcagttttaa agatttcttt gatagtatag ccttttttag
    37501 ttcctaagtt aaagatttga gaagaactgt cttcttgaaa taggtagttc attcctttaa
    37561 catgagccta tgcaaggtcc aagacataaa tgtaatctcg aatacatgaa ccgtcacgtg
    37621 tatcgtagtc atctccaaat atttttaagc tatcattttg tcccaatgcg gtcttgttga
    37681 tatttggaat gatgtgagtt ggatttttca cacgcagacc gtttgaagca tccatttcag
    37741 ccccagcagc attaaagtaa cggaaaataa catatttcca gtcgtagcga ttggccatcc
    37801 agtaaatcat tcgttcgccc atcagttttg tctctgcata agggttgaca gggtcgagca
    37861 gggtatcttc agtcaccggc ttgtcaatac agttatttcc atagagagaa gcagtcgaag
    37921 agaacatgat tttttgaatg ccaacttcag ataagacttt gagaacttgg ttcataccag
    37981 caacgttggc agtgaagtat ttacttggat tttcaatact ttcgctcaca acaatttcac
    38041 ctgcacaatg gaggacagca tcaatctgat tttcttctaa gtaagccttt aaggcgctag
    38101 catcataaac atccagttct ttaaagctag cacgactatc cacagccgct cgatttcctg
    38161 tggagagatt atcgaggaca tgcacctgat agccagcatt taaaagagct ttaacggtat
    38221 gggagctaat gtagctagtc ccacctgtaa caagaattgt tttggtcatg attttttcct
    38281 tttctagttt tgtactatag taaattgaaa taagatatga acaact
//
LOCUS       DAVLZG010000012        38235 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLZG010000012 DAVLZG010000000
VERSION     DAVLZG010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38235
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.012"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            121..1146
                     /gene="trpS"
                     /locus_tag="VYO72_000598"
     CDS             121..1146
                     /gene="trpS"
                     /locus_tag="VYO72_000598"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1707016.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            1298..2776
                     /gene="guaB"
                     /locus_tag="VYO72_000599"
     CDS             1298..2776
                     /gene="guaB"
                     /locus_tag="VYO72_000599"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1707017.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(2827..3924)
                     /gene="recF"
                     /locus_tag="VYO72_000600"
     CDS             complement(2827..3924)
                     /gene="recF"
                     /locus_tag="VYO72_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1707018.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(3927..4295)
                     /gene="yaaA"
                     /locus_tag="VYO72_000601"
     CDS             complement(3927..4295)
                     /gene="yaaA"
                     /locus_tag="VYO72_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1707019.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            4454..5704
                     /locus_tag="VYO72_000602"
     CDS             4454..5704
                     /locus_tag="VYO72_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1707020.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            5701..6984
                     /locus_tag="VYO72_000603"
     CDS             5701..6984
                     /locus_tag="VYO72_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1707021.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            7026..7847
                     /locus_tag="VYO72_000604"
     CDS             7026..7847
                     /locus_tag="VYO72_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1707022.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            7858..8403
                     /gene="pgsA"
                     /locus_tag="VYO72_000605"
     CDS             7858..8403
                     /gene="pgsA"
                     /locus_tag="VYO72_000605"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1707023.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            8400..9227
                     /locus_tag="VYO72_000606"
     CDS             8400..9227
                     /locus_tag="VYO72_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1707024.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            9212..10051
                     /locus_tag="VYO72_000607"
     CDS             9212..10051
                     /locus_tag="VYO72_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1707025.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            10044..10838
                     /locus_tag="VYO72_000608"
     CDS             10044..10838
                     /locus_tag="VYO72_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1707026.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            10897..11715
                     /gene="mreC"
                     /locus_tag="VYO72_000609"
     CDS             10897..11715
                     /gene="mreC"
                     /locus_tag="VYO72_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1707027.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            11715..12209
                     /gene="mreD"
                     /locus_tag="VYO72_000610"
     CDS             11715..12209
                     /gene="mreD"
                     /locus_tag="VYO72_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1707028.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            12303..13481
                     /locus_tag="VYO72_000611"
     CDS             12303..13481
                     /locus_tag="VYO72_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1707029.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            13705..14484
                     /gene="rpsB"
                     /locus_tag="VYO72_000612"
     CDS             13705..14484
                     /gene="rpsB"
                     /locus_tag="VYO72_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1707030.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGHQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            14563..15603
                     /locus_tag="VYO72_000613"
     CDS             14563..15603
                     /locus_tag="VYO72_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1707031.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            15849..16172
                     /gene="tnpB"
                     /locus_tag="VYO72_000614"
                     /pseudo
     CDS             15849..16172
                     /gene="tnpB"
                     /locus_tag="VYO72_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(16313..16600)
                     /locus_tag="VYO72_000615"
                     /pseudo
     CDS             complement(16313..16600)
                     /locus_tag="VYO72_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16591..16989
                     /locus_tag="VYO72_000616"
     CDS             16591..16989
                     /locus_tag="VYO72_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1707032.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(17186..18106)
                     /gene="cysK"
                     /locus_tag="VYO72_000617"
     CDS             complement(17186..18106)
                     /gene="cysK"
                     /locus_tag="VYO72_000617"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1707033.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(18391..19026)
                     /locus_tag="VYO72_000618"
     CDS             complement(18391..19026)
                     /locus_tag="VYO72_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1707034.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19082..20380
                     /locus_tag="VYO72_000619"
     CDS             19082..20380
                     /locus_tag="VYO72_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1707035.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            20377..21039
                     /locus_tag="VYO72_000620"
     CDS             20377..21039
                     /locus_tag="VYO72_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1707036.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            21119..21667
                     /gene="raiA"
                     /locus_tag="VYO72_000621"
     CDS             21119..21667
                     /gene="raiA"
                     /locus_tag="VYO72_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1707037.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            21803..23776
                     /locus_tag="VYO72_000622"
     CDS             21803..23776
                     /locus_tag="VYO72_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1707038.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQIIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            23773..24225
                     /gene="rplI"
                     /locus_tag="VYO72_000623"
     CDS             23773..24225
                     /gene="rplI"
                     /locus_tag="VYO72_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1707039.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            24268..25620
                     /gene="dnaB"
                     /locus_tag="VYO72_000624"
     CDS             24268..25620
                     /gene="dnaB"
                     /locus_tag="VYO72_000624"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1707040.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            25622..25888
                     /locus_tag="VYO72_000625"
     CDS             25622..25888
                     /locus_tag="VYO72_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707041.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            25977..27323
                     /gene="cbpD"
                     /locus_tag="VYO72_000626"
     CDS             25977..27323
                     /gene="cbpD"
                     /locus_tag="VYO72_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1707042.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      27406..27508
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            27579..27869
                     /locus_tag="VYO72_000627"
     CDS             27579..27869
                     /locus_tag="VYO72_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1707043.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            27832..28590
                     /locus_tag="VYO72_000628"
     CDS             27832..28590
                     /locus_tag="VYO72_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707044.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            28629..29636
                     /locus_tag="VYO72_000629"
     CDS             28629..29636
                     /locus_tag="VYO72_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1707045.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            29636..30361
                     /locus_tag="VYO72_000630"
     CDS             29636..30361
                     /locus_tag="VYO72_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707046.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            30484..30942
                     /locus_tag="VYO72_000631"
     CDS             30484..30942
                     /locus_tag="VYO72_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1707047.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            30944..33376
                     /locus_tag="VYO72_000632"
     CDS             30944..33376
                     /locus_tag="VYO72_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1707048.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            33697..34350
                     /gene="rr06"
                     /locus_tag="VYO72_000633"
     CDS             33697..34350
                     /gene="rr06"
                     /locus_tag="VYO72_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1707049.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            34347..35678
                     /gene="hk06"
                     /locus_tag="VYO72_000634"
     CDS             34347..35678
                     /gene="hk06"
                     /locus_tag="VYO72_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1707050.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            35761..36288
                     /locus_tag="VYO72_000635"
     CDS             35761..36288
                     /locus_tag="VYO72_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1707051.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            36367..>38235
                     /locus_tag="VYO72_000636"
     CDS             36367..>38235
                     /locus_tag="VYO72_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV1707052.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKPRVRRNSPEIKAKGRVKNYEEANIELSKYMTDLY
                     KLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFAD
                     LLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGG
                     QAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDG
                     AKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKA
                     KLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKK
                     EKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQ"
BASE COUNT        12034 a         6212 c         8406 g        11583 t
ORIGIN      
        1 tatatttaca gtatccttta cacaaatctg taaaaagcaa ggctgattta ttttgataaa
       61 ttacggttat ttcattaaaa aaatgctata attgaaagga ctatatcgaa ggagaacaaa
      121 atgactaaac ccattatttt aacaggagac cgtccaacag gaaaattgca tattggacat
      181 tatgttggaa gtctcaaaaa tcgagtatta ttacaggaag aggataagta tgatatgttt
      241 gtgttcttgg ctgaccaaca agccttgaca gatcatgcca aagatcctca aaccattgta
      301 gagtctatcg gaaatgtggc tttggattat cttgcagttg gattggatcc aaataagtca
      361 actattttta ttcaaagcca gattccagag ttggctgagt tgtctatgta ttatatgaat
      421 ctagtttcgt tagcacgttt ggagcgaaat ccaacagtca agacagagat ttctcagaaa
      481 ggatttggag aaagcattcc gacaggattc ttggtctatc caatcgctca agcagctgat
      541 atcacagctt tcaaggctaa ttatgttcct gttgggacag atcagaaacc aatgattgag
      601 caaactcgtg aaattgttcg ttcttttaac aatgcatata actgtgatgt cttggtagag
      661 ccggaaggta tttatccaga aaatgagaga gcagggcgtt tgcctggttt agatggaaat
      721 gctaaaatgt ctaaatcact aaataatggt atttatttag ctgatgatgc ggatactttg
      781 cgtaaaaaag taatgagtat gtatacagat ccagatcata tccgcgttga ggatccaggt
      841 aagattgagg gaaatatggt tttccattat ctagatgttt ttggtcgtcc agaagatgct
      901 caagaaattg ctgatatgaa agaacgttat caacgaggtg gtcttggtga tgtgaagacc
      961 aagcgttatc tacttgaaat attagaacgt gaactgggtc ctattcgtga gcgccgtatt
     1021 gaatttgcta aggatatggg agaagtttat aatatgattc aaaaaggtag tgaaagagcg
     1081 cgtgaagttg cgggtcaaac cctatctgag gtaaaagggg caatgggact tcattacttt
     1141 aattaagttt attttacaag aaactatcat ttctatctcg aagaaaagat agttttttat
     1201 ttacccctgt aacatttgac aaatttttat agaatggtat gatagataca atataaaaag
     1261 agtcaagctc aaaaagaaag aaaagaggaa acttcgaatg tctaattggg acactaaatt
     1321 tttgaaaaaa ggttttacct ttgatgatgt attgcttatt ccagctgaaa gtcatgtgtt
     1381 gcctaacgat gcagatttaa caactaaatt ggcagataat ttgactttaa atatcccaat
     1441 tattaccgct gccatggaca cagttacaga gagtcaaatg gccattgcta ttgctcgtgc
     1501 aggtggtctc ggagttatcc ataaaaacat gtcaattgct caacaagcag acgaggttcg
     1561 taaggtaaaa cgttctgaaa atggagttat tattgatccg ttcttcttga cgcctgaaca
     1621 tacaattgct gaagcagatg agcttatggg tcgttaccgc atcagtggtg ttccagttgt
     1681 tgaaacactt gaaaatcgta aattggttgg tattttgaca aaccgagatc ttcgttttat
     1741 ttcagattat aatcaaccaa tttcaaacca tatgactagt gaaaatcttg ttactgctcc
     1801 tgtgggtacg gatcttgcaa cggctgagag tattcttcaa gagcatcgta ttgaaaaact
     1861 tccgttggtc gatgaagaag gcagtctttc tggtttgatc actatcaaag atattgaaaa
     1921 agttattgag tttccaaatg cggctaaaga tgaatttggt cgtcttctag ttgcaggtgc
     1981 agtaggtgtt acttcagata catttgaacg tgcagaggct ctttttgagg caggagcgga
     2041 tgcgattgtt attgatactg cacatggtca ttctgcaggt gtcttgcgta aaattgccga
     2101 gattcgtgct catttcccag atcggacttt gattgctgga aatattgcta ctgctgaagg
     2161 tgcacgtgcc ctttatgaag cgggtgtaga cgttgttaag gttggtattg gaccaggttc
     2221 tatctgtact actcgtgtga ttgctggtgt tggtgttccg caagtaacag ctatctacga
     2281 tgctgcagct gttgcgcgcg aatatggtaa aacgattatt gctgacggtg ggatcaagta
     2341 ttctggagat attgtaaaag cacttgctgc aggtggaaat gctgttatgc ttggatctat
     2401 gtttgctgga actgatgaag ctccaggcga aactgaaatc ttccaaggac gtaaattcaa
     2461 gacttaccgt ggtatgggat caattgctgc tatgaagaaa ggttcaagcg accgttattt
     2521 ccaaggttct atcaatgaag caaacaagct cgttccagaa ggaattgaag gtcgtgttgc
     2581 ttataaagga gcggcagctg atattgtttt ccaaatgatt ggtggtattc gctctggtat
     2641 gggttactgt ggtgcagcta accttaaaga actacacgat aatgctcaat ttattgaaat
     2701 gtctggtgct ggtttgaaag aaagccatcc tcatgatgtg caaattacta atgaggcacc
     2761 aaattattct atgtaaaaaa caatgaaaag aactccagtg aaaacaggag ttcttttaca
     2821 atgttgtcaa tttccattta cagcagcttt accatcctga atagtgaaga tacttagatt
     2881 ttctggtaga ttttgaagat ggtctaagct tgttgttgtg ataaaggttt ggattgattg
     2941 agaaatcgtt tctaataatt ttaattgtct agtgttgtca agttcactca tcacatcgtc
     3001 aagcagtaat ataggagatt ctgtggtaat gctttccatt aattcgattt ctgctaattt
     3061 tatcgagagg acgagactac gatgttgacc ttggcttccg aaactagcat ccatcccatt
     3121 tatataaaaa gaaatgtcat ctcgatgagg accgacacca gtattctttt taaataaatc
     3181 tctggattta cttttttcta aagcaatttt gaaagattcg gataagtttt gtttgtcagt
     3241 tatattgaca gaagattgat aggatattga caactcttcg atctgattag agagttcaaa
     3301 atgtttctta cgcccaaatg attctagttt ttttatgaaa tctaagcggt gattcattac
     3361 acgacatcca taatcaacta gctgatcatc taacacagaa aggaatgttt catctatttt
     3421 ttgatctgat tttaggtaag tgtttctttg ctttaggatg tggttataat tggttaagtc
     3481 agataagtag attggcttaa tttgcccaag ttccatatcg atgaattttc gtcgaatcga
     3541 aggtgctcct ttaattagtt gtaaatcttc aggagcaaat aagacaacat tcatgtgtcc
     3601 tacataatct gaaaggcgtg cctgttttaa gtgattaact tttgttacac ggcctttttg
     3661 tgttagttcg atttctaggg gaatggatcc agtttttttc tgaacgagac ctgaaagatg
     3721 aagttgttcc tcatcaaaat gaatgagatt tttatctgtt cgagttcgat gactacgcgt
     3781 taaggctaaa aaatagatag cctctaacat gtttgttttt ccttgtgcat tacgtcccaa
     3841 aaagacattc aatttaggat taaagtctat tttcgtttct ttgtaattac gaaaagtctt
     3901 gagagataga tgttgtagcc acatgattat ctaccaggga atcgtggagc ttgttggctt
     3961 ttaggtgatg aagcaggttt cgatttgtct tttttaactc ccttattcat ctttttgaca
     4021 agtttagcga tccgttcttt ttcaacttta tcagcttggt attcatcttg ttcttcagaa
     4081 gtaggttgtg tcaacaagat gtcaatgttc atgtcaggga tgtcaacttt atcgccaata
     4141 cgaagttttt ttccacgacg actctctaat tccctattaa agtaaacaga atgttcagag
     4201 agaaatgatt taatagctcc tccgctatgt gtaattccaa gttctttgag tagtgcttgg
     4261 agggtaataa attcttcaaa taatttgtat tccataattc acctcaatct ttggtattat
     4321 accatatttt cctaaaaata gtgagagaga cagcgagaaa tgtaagcgat ttttatttca
     4381 aaagtgttac agggaacaag aaaatttcag gttttcgtga tataatagaa gtctgtatat
     4441 aaggaggtaa atcatggagt tagtgcatgg aatttcaaca cattttatcc aatcaaaaaa
     4501 gtttaaaaca aacaaaatta ccgtgcgttt taccgctcca ttatcccttg atacgattgc
     4561 aggtcacatg ttgagtgcaa gtatgctaga gactgctaat cagatgtacc ccacttctca
     4621 agatttgagg agacacttgg ccagtctata cggtacagat atgtcaacca attgtttcag
     4681 aagagggcaa agccacatta tagaattgac atttacctat gttcgtgatg agtttttaag
     4741 taggaaaaac gtgctaacct ctcagatttt ggaacttgta aaagaaactc ttttttcacc
     4801 cgtagtagtt gataatgggt ttgatccggc cttatttgaa attgagaaaa aacaattgct
     4861 agcaagttta gcagctgata tggatgattc tttttatttt gcacataaag aattggataa
     4921 attgtttttt catgatgaac gtcttcaatt ggaatatagt gatttacgaa atcgtatttt
     4981 agctgaaact ccacaaagtt cttactcttg tttccaagaa tttttagcca atgatcgaat
     5041 agatttcttt ttcctaggtg attttaatga ggttgaaatt caaaatgtat tagaatcatt
     5101 tggctttaaa ggtcgaaaag gagatgtgaa ggttcagtat tgtcaacctt attctaatat
     5161 ccttcaggaa ggtatggttc ggaaaaatgt gggacaatcc attttggaat taggttatca
     5221 ttaccgttct aaatatggtg atgaacaaca tttacccatg attgtaatga atggtttact
     5281 tggtggattt gctcactcta agctctttac aaatgtccgt gaaaatgctg gattagctta
     5341 taccatttca agtgagcttg atttatttag tggattcttg aggatgtatg ctggtatcaa
     5401 tcgagaaaat cgtaaccagg ctcgtaaaat gatgaataat caactgcttg atttaaaaaa
     5461 aggttatttt acagagtttg agttaaatca gaccaaggaa atgattcgtt ggtcgttgtt
     5521 actttctcaa gataatcaat cttcattgat tgaacgtgct tatcaaaatg ccttatttgg
     5581 aaaatcttca gcagacttta aaagttggat tgcaaagctt gaacaaattg acaaagatgc
     5641 tatttgtaga gtagctaata atgtgaaact acaagcgatt tactttatgg aaggaataga
     5701 atgacaaagg ttgtttttga agaaaaatac tatccagctg taaaagaaat ggtttatcga
     5761 actcgtttgg ccaacggatt gacagttgct cttttgccta aaaaggaatt taaagaggtt
     5821 tacgggagtg tcactgtaca gtttggttcg gtagatacgt ttgtcacaga agttgacgga
     5881 gatgtaaaac aatatcctgg aggaattgct cattttcttg aacataaatt atttgagaga
     5941 gaagattcta gtgatttgat gtcggctttt acgagtctag gtgcagatag taatgccttt
     6001 acaagcttta caaaaacaaa ctatcttttt tcagcaacgg attatttttt agaaaattta
     6061 gatttacttg atgaattggt aacatcagca cactttactg aagcttccat tttgacagag
     6121 caggatatta ttcagcaaga acgagaaatg taccaagatg atccagattc gtgtttattc
     6181 ttttcaactt tagcgaattt gtatcctggt acacctttag caactgatat agttggaagt
     6241 gaggagtcca tttcccaaat caatctaact aatttgcaag aaaattttac aaagttttac
     6301 aaacctgtaa acatgtctct gtttttagtt ggtaattttg atgtggagcg agtacaggac
     6361 tattttgaaa gcaaagaact gaaagattca gattttcagg aagtagcaag agaaaagttg
     6421 tttttacagc ctgtaaagcc aacagatagt atgagaatgg aagtatcttc tcccaaacta
     6481 gcgattggag ttagaggtaa gcgagaagtt tctgaagcgg attgctatcg acatcatatt
     6541 ttattaaaat tattgtttgc aatgatgttt ggttggactt cggatcgttt tcaaaaatgt
     6601 tatgaatcag gtaaaattga tgcatcctta tctctggaag ttgaagtaac aagtcgcttt
     6661 cattttgtca tgttgacaat ggatacgaaa gagccagttg ctttgtctca tcaatttagg
     6721 aaggctattc gtaattttac aaaggattta gatattacag aggaacattt agatattatc
     6781 aaaagagaga tgtttggcga atttttcagt agcatgaact ctcttgaatt tattgcaacg
     6841 caatatgatg cttttgaaaa tggtgagaca atttttgatt tgccgaaaat tttacaggaa
     6901 attactttag aggatgtcct tgatgctgga catcatttaa tagatgatgg tgacatagtt
     6961 gattttacaa tattcccatc gtagtaacct attataatag acactagaaa gaagggatga
     7021 caagtatgag aaaaaaaaca attggagagg ttttacgatt agctagaatc aatcagggat
     7081 tgagtttaga tgaattgcag aaaaagacag aaatccagtt agatatgttg gaagcaatgg
     7141 aagcagacga tttcgatcaa cttccaagtc ctttttacac gcgttctttc ttgaaaaaat
     7201 atgcatgggc tgttgagtta gatgaccaaa ttgttttgga tgcttatgat tctgggagta
     7261 tgattactta tgaggaagta gatgttgatg aagatgagtt gacaggtcgt agacgttcaa
     7321 gtaagaaaaa gaagaaaaaa acatcatttt tacctttatt ttattttatc ctttttgctt
     7381 tatcgatttt aatttttgtg acttattatg tttggaacta tattcaaact caaccagagg
     7441 agccttctct ttctaattac agtgtggttc aatcaacaag ttcaactagc tctgttcccc
     7501 actcctcaag tagtagttct tctagtatag aatcagctat aagtgtatca ggcgaaggaa
     7561 atcatgtaga aatcgcttat aagacaagta aggaaacagt taaattgcaa ttggcagttt
     7621 cagatgttac aagttgggtc agtgtttcag aaagcgaact tgagggcggt gtaaccttat
     7681 cgccaaagaa gaaaagtgca gaagcaacag ttgcaactaa aagtcctgta acaattacgt
     7741 taggtgttgt aaaaggtgtt gatttgacag tagataatca gactgttgat ttatcgaaat
     7801 taacagctca gactggacaa atcactgtaa cctttactaa aaattaagga aaaacgaatg
     7861 aaaaaagaac aaattcccaa tctcttaaca ataggtcgaa ttctctttat acctattttt
     7921 atctttattt taacgatagg aaattcgata gagagtcata tagttgcagc tattatcttt
     7981 gctgttgcca gtattaccga ctatttagat ggatatttag ctcgtaaatg gaatgtggtc
     8041 agtaattttg gtaaatttgc agatcctatg gcggataagt tactagttat gtcggctttt
     8101 attatgttga ttgagttagg tatggctccg gcttggattg ttgcagtgat tatctgtcgt
     8161 gagttagctg tgacaggttt aaggctttta ttggttgaaa ctggtggaac aattttagca
     8221 gcagcaatgc ctggaaaaat taaaactttt agtcagatgt ttgctattat tttcttgcta
     8281 ttacattgga ctttgcttgg tcaagttcta ctttatgtag ccttattttt cactatctac
     8341 tctggctatg actatttcaa gggtagtgcc tatgtattta aagggacatt tggttcgaaa
     8401 tgaaatcaat aattgatgta aaaaatcttt cttttcgcta taaagaaaat cagaactact
     8461 acgatgtgaa ggatattacg tttcacgtga aacgtggaga atggctttcg attgtagggc
     8521 ataatggtag tggtaaatca actacggttc gattaattga tggcttactg gaagcagaat
     8581 ccggagagat tgtaattgat ggccaacgtt tgactgagga aaatgtttgg aatatacgtc
     8641 gtcaaatcgg tatggttttt caaaatccag acaatcaatt tgttggagcg actgttgaag
     8701 atgatgttgc ttttggtttg gaaaatcagg gactttctcg tcaagaaatg aaaaagagag
     8761 tggaagaagc tctggcttta gttggcatgt tggactttaa aaagagagag ccagcgcgtc
     8821 tatcaggtgg tcaaaagcaa cgtgtggcca ttgcaggtgt tgtagcccta agaccagcta
     8881 ttttaatctt agatgaagca acgagtatgt tggatcctga ggggcgtaga gaacttattg
     8941 ggacagtaaa aggaattcga aaagactatg atatgacggt catttctatt acccatgatt
     9001 tggaagaagt cgccatgagt gatcgcgtat tggtcatgaa aaaaggggaa attgaatcaa
     9061 ctagtagtcc aagggagctt ttctctcgaa atgatttaga tcaaattgga ttagacgatc
     9121 cttttgctaa tcaattaaaa aaatctttga gccagaatgg ctatgattta cctgaaaatt
     9181 atttgacaga aagtgagcta gaggataagc tatgggaatt gctctagaaa atgtgaattt
     9241 tacatatcaa gaaggtactc ccttagcttc agcagctttg tcggatgttt ctttgacgat
     9301 tgaagatggc tcttatacag ctttaattgg gcacacaggt agtggtaaat caactatttt
     9361 acaactctta aatggtttat tggtgccaag tcaagggagt gtgagggttt ttgatacctt
     9421 aatcacctcg acttctaaaa ataaagatat tcgtcaaatt agaaaacagg ttggcttggt
     9481 atttcagttt gctgaaaatc agatttttga agaaacggtt ttgaaggacg ttgcttttgg
     9541 accgcaaaat tttggagttt ctgaagaaga tgctgtgaag actgcgcgtg agaaactggc
     9601 tctggttgga attgatgaat cactttttga tcgtagtccg tttgagctgt cagggggaca
     9661 aatgagacgt gttgccattg caggcatact tgccatggag ccagctatat tagtcttaga
     9721 tgagccaaca gctggtctag atcctctagg gagaaaagag ttgatgaccc tgttcaaaaa
     9781 actccaccag tcagggatga ccatcgtctt ggtaacgcat ttgatggatg atgttgctga
     9841 atatgcaaat caagtctatg taatggaaaa gggacgttta gtaaaggggg gcaaaccaag
     9901 tgatgtcttt caagacgttg tttttatgga agaagttcag ttgggagtac ctaaaattac
     9961 ggccttttgt aaacgattgg ctgatagagg cgtgtcattt aaacgattac cgattaagat
    10021 agaggagttc aaggagtcgc taaatggata gtatgatttt ggggcgttat atcccagggg
    10081 attcgattgt tcaccgattg gatccacgta gcaaattgct tgctatgatg ctactgattt
    10141 tgattgtgtt ttgggctaat aaccccttga cgaatctgat tctttttata gcgacaggga
    10201 tatttattgc cttgtcagga gtatctcttt cattttttat tcagggcttg aagtctatgt
    10261 ttttcttgat tgccttcaca actatttttc aactattttt catttctaat gggaatgttt
    10321 tatttgagtt ttcgtttgtg agaatcacgg attatgcttt gcaacaagct gggattattt
    10381 tttgtcgctt tgtattgatt attttctttt caactttgtt aaccttaaca accatgcctt
    10441 taagtttggc atcagctgtc gaagctttat tagcaccttt aaagcgtgtg aaagttccag
    10501 ttcatgaaat tggattgatg ctgtctatga gtttgcgttt tgtcccaacc ttgatggatg
    10561 atacgactcg gattatgaat gcacagaaag ctcgtggagt ggattttgga gaaggaagca
    10621 tcgttcaaaa agtaaaggcg atgattccca ttttgattcc tctttttgcg acaagtttaa
    10681 aacgtgcaga ttccttggct atcgctatgg aagcgcgtgg ctatcagggt ggaaaaggca
    10741 gaagtcaata ccgacaattg aaatggactc taaaggatac gctgaccatt cttgttattc
    10801 tcgtacttgg ttgttgttta tttttcttaa aatcttagta gctttcagga attgataaaa
    10861 agttactgta acagtttttg atataaaggt agggatatga accgttttaa aaaatcaaaa
    10921 tatgtcatta ttgtttttgt cactgttctg cttgtgtcag ctctcttagc gacgacttat
    10981 tcaagtacaa ttgtgacaaa attaggagat ggaatctcat tggttgatag agttgtacaa
    11041 aaaccttttc agtggtttga ttctgtcaaa tcagatttgg ctcatttgac acgaacatat
    11101 aatgaaaatg aaagtttgaa gaaacagctt taccaattag aagttaaatc aaatgaggtg
    11161 gaaagtttaa agacagaaaa tgaacaactg cgccaattgc ttgatatgaa gtctaaattg
    11221 caagccacaa agactttagc agcagatgtt attatgcgtt ctccggtatc ttggaagcag
    11281 gagttgacct tagatgcagg tagatcaaaa ggtgcttctg agaacatgtt agctattgca
    11341 aatggtggct tgattgggag tgtttcaaaa gtagaggaga actctactat agtcaacctt
    11401 ctgacaaata cggaaaatgc tgataagatt tctgttaaaa ttcaacatgg ctctactaca
    11461 atttatggaa ttattattgg ctatgacaag gaaaatgacg ttcttaaaat tagccaatta
    11521 aatagtaata gcgatattag tgcgggagat aaggtgacta ctggtggatt aggaaacttt
    11581 aacgttgctg atattcctgt tggtgaagtg gttgccacaa cgcatagtac agactatttg
    11641 acacgagaag taactgttaa attgagtgca gatactcata atgtagatgt gatagaatta
    11701 gtggggaatt cataatgaga cagttgaagc gagttggagt atttttattg cttcctttct
    11761 ttgttctaat tgacgcccat attagccagc ttctgggctc atttttcccc catgtacatt
    11821 tggctagtca ttttcttttt ctatttctct tatttgagac gatagaagta tcagagtatc
    11881 tctacctagt ctattgtttt gttataggct tggtttatga tgtttacttt ttccatctaa
    11941 tagggattac aactctctta tttatcttat tgggagcctt ccttcataaa ttgaatagtg
    12001 ttattttgtt gaatcgttgg acaagaatgc tagctatgat tgtgctgaca ttcctgtttg
    12061 aaatgggtag ttatcttttg gcttttatgg tagggttgac agtagatagc atgtcgattt
    12121 ttatagtcta tagcttggta ccgacgatga ttttaaattt tttatggatt actgtttttc
    12181 aatttatttt tgaaaaatat tatctataag aacgacatat aaatgtaaca aaggcgtaat
    12241 atttattagg cctttttttg gtatactagt attgtcttta aaagaaggag tatctacgta
    12301 atatgaagaa aaaaatctta gcgtcacttt tattaagtac agtaatggtt tctcaagtag
    12361 ctgttttaac aactgcgcat gcagaaacga ctgatgacaa aattgctgct caagataata
    12421 aaattagtaa cttaacagca caacaacaag aagcccaaaa acaagttgac caaattcagg
    12481 agcaagtatc agctattcaa gctgagcagt ctaacttgca agctgaaaat gatagattac
    12541 aagcagaatc taagaaactc gagggtgaga ttacagaact ttctaaaaac attgtttctc
    12601 gtaaccaatc gttggaaaaa caagctcgta gtgctcaaac aaatggagcc gtaactagct
    12661 atatcaatac cattgtaaac tcaaaatcaa ttacagaagc tatttcacgt gttgctgcaa
    12721 tgagtgaaat cgtatctgca aacaacaaaa tgttagaaca acaaaaggca gataaaaaag
    12781 ctatttctga aaaacaagta gcaaataatg atgctatcaa tactgtaatt gctaatcaac
    12841 aaaaattggc tgatgatgct caagcattga ctacgaaaca ggcagaacta aaagctgctg
    12901 aattaagtct tgctgctgag aaagcgacag ctgaagggga aaaagcaagt ctattagagc
    12961 aaaaagcagc agctgaggca gaggctcgtg cagctgcggt agcagaagca gcttataaag
    13021 aaaaacgagc tagccaacaa caatcagtac ttgcttcagc aaacactaac ttaacagctc
    13081 aagtgcaagc agtatctgaa tctgcagcag cacctgtccg tgcaaaagtt cgtccaacat
    13141 acagtacaaa cgcttcaagt tatccaattg gagaatgtac atggggagta aaaacattgg
    13201 caccttgggc tggagactac tggggtaatg gagcacagtg ggctacaagt gcagcagcag
    13261 caggtttccg tacaggttca acacctcaag ttggagcaat tgcatgttgg aatgatggtg
    13321 gatatggtca cgtagcggtt gttacagctg ttgaatcaac aacacgtatc caagtatcag
    13381 aatcaaatta tgcaggtaat cgtacaattg gaaatcaccg tggatggttc aatccaacaa
    13441 caacttctga aggttttgtt acatatattt atgcagatta atttacagag ggactcgaat
    13501 agagccctct tttcaggttt taccgtgaca atccctatta aaaattatat caaaatagct
    13561 tgaaaatatt ggaaaagtat ggtagaatga aaattgtcgt gtgaacgata atactcattc
    13621 ttgatgaatt gtgaagcagt tgcccttggg tcgttttgcg agttgaagtc aagaagagga
    13681 aaaaaacaaa aaggagaaat actcatggca gtaatttcaa tgaaacaact tcttgaggct
    13741 ggtgtacact ttggtcacca aactcgtcgc tggaatccta agatggctaa gtacatcttt
    13801 actgaacgta acggaatcca cgttatcgac ttgcaacaaa ctgtaaaata cgctgaccaa
    13861 gcatacgact tcatgcgtga tgcagcagct aacgatgcag ttgtattgtt cgttggtact
    13921 aagaaacaag cagctgatgc agttgctgaa gaagcagtac gttcaggtca atacttcatc
    13981 aaccaccgtt ggttgggtgg aactcttaca aactggggaa caatccaaaa acgtatcgct
    14041 cgtttgaaag aaattaaacg tatggaagaa gatggaactt tcgaagttct tcctaagaaa
    14101 gaagttgcac ttcttaacaa acaacgtgcg cgtcttgaaa aattcttggg tggtatcgaa
    14161 gatatgcctc gtatcccaga tgtgatgtac gtagttgacc cacataaaga gcaaatcgct
    14221 gttaaagaag ctaaaaaatt gggaatccca gttgtagcga tggttgacac caatactgat
    14281 ccagatgata tcgatgtaat catcccagct aacgatgacg ctatccgtgc tgttaaattg
    14341 atcacagcta aattggctga cgctattatc gaaggacatc aaggtgagga tgcagtagca
    14401 gttgaagcag aatttgcagc ttcagaaact caagcagatt caattgaaga aatcgttgaa
    14461 gttgtagaag gtgacaacgc ttaatttata caaatagtaa ttacctagga gggcggggct
    14521 tagcccggct ctcctatttt caaaaaatat aggagaatta aaatggcaga aattacagct
    14581 aaacttgtaa aagagttgcg tgaaaaatct ggtgccggtg ttatggacgc taaaaaagcg
    14641 cttgtagaaa cagacggtga catcgaaaaa gcgattgaat tgcttcgtga aaaaggtatg
    14701 gctaaggcag ctaagaaagc tgaccgtgtt gctgcagaag gtttgactgg tgtttatgtt
    14761 aacggtaatg ttgcagcagt tattgaagta aacgctgaaa ctgacttcgt tgcaaaaaac
    14821 gctcaattcg ttgaattggt aaatactaca gctaaagtca ttgctgaagg aaaacctgct
    14881 aacaatgaag aagctcttgc tttgataatg ccttcaggtg aaactcttga agctgcatac
    14941 gtatctgcaa cagcaactat cggagagaaa atctcattcc gtcgctttgc attgattgaa
    15001 aaaacagacg cacaacactt tggagcatac caacataacg gtggacgtat cggtgttatt
    15061 tcagttgttg aagatggaga cgaagcactt gctaaacaat tgtcaatgca catcgcagcg
    15121 atgaaaccaa cagttctttc ttacaaagaa ttggatgagc aattcgttaa agatgagttg
    15181 gcacaattga atcacgttat cgaccaagac aacgaaagcc gtgcaatggt taataaacca
    15241 gctcttccac acttgaagta tggatcaaaa gctcaattaa ctgatgatgt tattgctcaa
    15301 gctgaagctg acatcaaagc tgaattggct gcagaaggca aaccagaaaa aatctgggac
    15361 aaaattattc caggtaaaat ggatcgcttc atgcttgata acactaaagt tgaccaagct
    15421 tacacacttc ttgcacaagt ttacatcatg gatgacagca agacagttga agcatacctt
    15481 gaatcagtta acgcttcggt agttgagttt gctcgctttg aagttggtga aggtatcgag
    15541 aaagctgcaa acgacttcga agctgaagtt gcagctacaa tggcagcagc cttgaataac
    15601 taataataga aaggaagcaa attgcttcct tttttgtata gggcttagat ttttcctgaa
    15661 attgtttttt ccccagtctc actcgattag aataattaaa acaaaaagcc ctataataag
    15721 ggctaagtgc atttaggaga ctatacttca aattcatagt aagcgcgtca taacaaggta
    15781 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaggt
    15841 attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga
    15901 cagatatgag gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
    15961 attctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
    16021 tttactggga tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga
    16081 cttggctaag tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta
    16141 tgaagggctt ttctatcact ccaaaaatat agtagattga aactagaata gtacacctct
    16201 gcttctaaaa cattgttaga aatcgatttg attgtcctgt tcttatttca ttttactata
    16261 aatccatcag aaagttgtga tttctattga aatgaggact ttctttttac actcatctgc
    16321 tttcaaaaag cattctagtc catctccgat taacgatgga ctttatcacc tccttctcca
    16381 gtccttgtat gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa
    16441 tctctttcca cacttgttca atggggttca tctctggtgt gtatggagga ataaatgcaa
    16501 agccaatatt agtcggaatc tttaaggtac ttgatttatg ccatatagca ttgtccataa
    16561 cgagtaaaag ataatcatct ggataagctt gtgaaagctc ctattcctaa agccccttta
    16621 gcgcatagct ttggctcagc ttctattatc gctcacacca tccatcagaa gtttaatctg
    16681 aaggtaccca attatcgcca agaagaagat tgggctaaga tgggtttacc aatcacacgc
    16741 aaggaaatct ctaattggca tatcaagacg agtcaatact atttggagcc cctctataac
    16801 ctcttgcgag agagactatt gactcagccc ttacttcatg cggatgaaac ttcttatagg
    16861 gtgctagaga gtgatagtca gctgacttac tattggactt ttttgtctgg gaaagctgag
    16921 aaacaaggga ttacgcttta ccatcatgtc ctaatcgatt tgttcatatc ttatttcaat
    16981 ccattataaa tagtgagaaa tatctatcct atcttctaga atgtcttcca aacgtggaaa
    17041 ctctcgtaaa caaagaggtt ttagaggctt atttaccatg gactaaagtt gtacaagaaa
    17101 agtgcaaata agaaatctcc agattaggaa ctatccgtga gttctctagt ctggagattt
    17161 ttcaatatac ttcgttattg gacggttaca attcataaag tgctgtagag agataacgtt
    17221 caccgttatc tggtgctagg acaaggactt ttttacctgt acctaatttt ttggcaacct
    17281 cgatggctcc gtagatagct gcagctgagg aaatccctac aaggaagcct tcttttccac
    17341 caatttcacg tccgagtgca agagcgtcat ctgatgttac acgaacgata ccatcatagg
    17401 ctttagtatc aagtgtatca ggaataaatc cagctgagat accttgaatt ttgtgaggac
    17461 caggtttttc accagataga atagcagatt catctgcttc tactgcaaaa acttgaatgt
    17521 tagaattttc tgatttgagt gcatgagaaa caccagaaat cgttccaccg gtacctactc
    17581 cagcaacaaa ggcatctaat ccatctttac cgaaagcagc tagtatctca gctcctgttg
    17641 ttctttcgtg tacttctgga ttagctggat tgtcaaattg aagaggaagg aaaccatcac
    17701 gttcagcagc gatttcttga gccttagcaa tagcaccttt cattccctcg ctaccaggag
    17761 ttaggacgag ttcagcacca taagcttgga taattttacg tcgttctaca ctcatagttt
    17821 caggcataac gatgacgact ttataccctt tagcagcacc tacccatgaa agtccaatac
    17881 cagtgtttcc acttgttgct tcaacaatag tagaaccagg tttcagaata ccatcttgtt
    17941 cagctttttc aatcatgcta agggcaatac ggtcttttac agatgaacca ggattaaatg
    18001 cttcaagctt tatatagacg tctgcagcac cttctggcac gatgttgtta agtttaacaa
    18061 tcggtgtttg accgattaat tcagtaatgt tgttataaat agacatatga atacctcttt
    18121 gtataagata tctttagtat aacgctatcc ataccatttg taaaatatag aaatcctatc
    18181 gaagcgatag gatttctata tatcatagat caaagtcatt aattttcaag tgattgcgtt
    18241 cagttaattc tagtaaatag gtgtgaagga aaacgatatc aggtttcgtt tgaattgctt
    18301 cattttctag tatattttgg tacgcatctt tttattttgc tcgctaaagt agttgtgaga
    18361 atgtcaacga aacgctgtat tattcattgt ttacactaag tttacaggaa cttcaacctc
    18421 tcgtaaacct tggtcagtta aagtgacttt tccattaaaa aactccacaa gtgcagcttt
    18481 aatagtttct ttttcttctt tatcaacata aatcatcgta tcgacttgat ctgtaaagtt
    18541 tgtatccagc tccatgagat catgttcttt aaggaagtta ctgtactctt ggtactgagc
    18601 ataagacatt tgaatagcaa tgccagcctg ttcttttatt tcaataatac caatttcttt
    18661 gacagctaag gcgacactgc cggcgtaagc acgaattagt cctccagcgc ctagtttaat
    18721 accaccaaag tagcgtgtca cgaccacaca gacattggtg agattgtgat tttctagtac
    18781 cccaagcatg ggaacaccag cagtaccact aggctcacca tcatcacttg tacgtttaat
    18841 ttcactacgt tctccaataa taaaggcaga gcagttatgt gtcgctttgt agtgttcttt
    18901 tttgatggca gtaatgaagt cacgagcctc ttcttcgcta taaacacgct tggcatggca
    18961 gataaagcga gattttttga tttcttcttg gacttggccg tcctctttaa ttgtcctaaa
    19021 ttccatgatt taattgtact aaaaaataat ctaaagtgct agtttttacg aataaagaag
    19081 tatgaaagta aatttagatt atctcggtcg tttatttact gagaatgaat taacagaaga
    19141 agaacgtcag ttggcggaga aacttccagc aatgagaaag gagaagggga aacttttctg
    19201 tcaacgttgt aatagtacta ttctagaaga atggtatttg cccatcggtg cttactattg
    19261 tcgagagtgc ttgctgatga agcgagtcag aagtgatcaa actttatact attttccgca
    19321 ggaggatttt ccgaagcaag atgttctcaa atggcgcggc caattaactc cttttcaaga
    19381 gaaggtgtca gagggactgc ttcaagcagt agacaagcaa aagccaacct tagttcatgc
    19441 ggtaacagga gctggaaaga cagaaatgat ttatcaagta gtggctaaag tgatcaatgc
    19501 gggtggtgca gtgtgtttgg ctagtcctcg catagatgtt tgtttggagc tgtacaagcg
    19561 cctgcaacag gatttttctt gcgggatagc tttgctacat ggagaatcgg aaccttattt
    19621 tcgaacacca ctagttgttg caacaaccca tcagttattg aagttttatc aagcttttga
    19681 tttgctgata gtggatgaag tagatgcttt tccttatgtt gataatccca cgctttacca
    19741 cgctgtcaag aatagtgtaa aggagaatgg attgagaatc tttttaacag cgacttcgac
    19801 caatgagtta gataaaaagg tccgtttagg agaactaaaa agactgagtt taccgagacg
    19861 gtttcatgga aatccgttga ttattccaaa accaatttgg ttatcggatt ttaatcgcta
    19921 cttagacaag aatcgtttgt caccaaagtt aaagtcctat attgagaagc agagaaagac
    19981 agcttatccg ttactcattt ttgcttcaga aattaagaaa ggggagcagt tagaagaaat
    20041 cttacaggag caatttccaa atgagaaaat tggctttgta tcttctgtaa cagaggatcg
    20101 attagagcaa gtacaagctt ttcgagatgg agaactgaca atacttatca gtacgacaat
    20161 cttggagcgt ggagttacct tcccttgtgt ggatgttttc gtagtagagg ccaatcatcg
    20221 tttgtttacc aagtctagtt tgattcagat tggtggacga gttggacgaa gcatggatag
    20281 accgacagga gatttgcttt tcttccatga tgggttaaat gcttcaatca agaaggcgat
    20341 taaggaaatt cagatgatga ataaggaggc tggtctatga agtgcttgtt atgtgggcag
    20401 actatgaaga ctgttttaac ttttagtagt ctcttacttc tgaggaatga tgactcttgt
    20461 ctttgttcag actgtgattc tacttttgaa agaattgggg aagagaactg tccaaattgt
    20521 atgaaaacag agttgtcaac aaagtgtcaa gactgtcaac tttggtgtaa agaaggagtt
    20581 gaagtcagtc atagagcgat ttttacttac aatcaagcta tgaaggattt tttcagtcgg
    20641 tataagtttg atggagactt cctgttaaga aaagttttcg cttcattttt aagtgaggag
    20701 ttgaaaaagt acaaagagta tcaatttgtt gtaattcccc taagtcctga tagatatgct
    20761 aacagaggat ttaatcaggt tgagggcttg gtagaggcag caggctttga gtatctggat
    20821 ttattagaga aaagagaaga gagagccagt tcttctaaaa atcgttcaga gcgcttgggg
    20881 acagaacttc ctttctttat taaaagtgga gtcactattc ctaaaaaaat cctacttata
    20941 gatgatatct atactacagg agcaactata aatcgtgtta agaaactgtt ggaagaagct
    21001 ggtgctaagg atgtaaaaac attttccctt gtaagatgag gaaaaaattt gcaaaaatag
    21061 aatgaaagcg ttataataaa atcataaaaa caaaaatgtt tagaaagaag gtactcatat
    21121 gattaaatat agtatccgtg gtgaaaacct agaagtaaca gaagcaattc gtgattatgt
    21181 agtttctaaa ctcgaaaaga tcgaaaagta cttccaacca gaacaagagt tggatgcccg
    21241 aattaactta aaagtttatc gtgaaaaaac ggctaaagtg gaagtaacga ttccgcttgg
    21301 atctattact ctccgcgcag aagatgtatc tcaagatatg tatggttcaa ttgaccttgt
    21361 aactgataaa attgaacgtc agattcgtaa aaataaaaca aaaatcgagc gtaaaaataa
    21421 aaataaggta gcaactggtc aattatttac agatgctttg gtggaagatt caaatattgt
    21481 ccagtctaaa gttgttcgtt caaaacaaat tgatttaaaa ccaatggatt tggaagaagc
    21541 aattctacaa atggatttat tggggcatga tttctttatc tatgtggatg ttgaagatca
    21601 gacaaccaat gtgatttatc gtcgtgagga tggcgaaatt ggtttgttag aggttaaaga
    21661 atcttaattt caatatgtgt aaaggtaggt ttactgaatt gtaaactacc tttttcttat
    21721 aattgataga attactgatt acacttttaa aaagtcgctt tttgaggggt attatggtat
    21781 aatgggtgcc aagaggtttt gaatgaaaaa attttatgta agtccaattt ttcctattct
    21841 agtaggattg attgcgtttg gagtcttatc cactttcatt atttttgtta ataataatct
    21901 gttgacggtt ttaattttgt ttctttttgt aggaggctat gtttttttat ttaagaaact
    21961 gagagtgcat tatacaagga gtgatgtaga acagatacag tatgtaaacc accaagcgga
    22021 agaaagtttg acagctctat tggaacagat gcctgtaggt gttatgaaat tgaatttatc
    22081 ttctggagag gttgagtggt ttaatcccta tgctgaattg attttgacca aggaagatgg
    22141 tgattttgat ttagaagctg ttcaaacgat tatcaaggct tcagtaggaa atccgtctac
    22201 ttatgccaag cttggtgaga agcgttatgc tgttcatatg gatgcttctt ccggtgtttt
    22261 gtattttgta gatgtatcca gggaacaagc cataacagat gaattggtaa caagtcgacc
    22321 agtgattggg attgtctctg tggataatta tgatgatttg gaggatgcaa cttctgagtc
    22381 agatattagt caaatcaata gttttgtagc taattttata tcagagtttt cagaaaaata
    22441 catgatgttt tctcgtcggg taagtatgga tcgattttat ctatttactg actacacggt
    22501 gcttgagggc ttgatgaatg ataaattttc tgttattgat gctttcagag aagagtcgaa
    22561 acagagacag ttgcccttga ccttaagtat gggattttct tatggcgatg gaaatcatga
    22621 tgagataggg aaagttgctt tgctcaattt gaacttggct gaagtacgtg gtggcgacca
    22681 ggtggttgtt aaggaaaacg acgaaacgaa aaatccagtt tattttggtg gtgggtctgc
    22741 tgcttcaatc aagcgtacac ggactcgtac gcgcgctatg atgacagcta tttcagataa
    22801 gattcggagt gtagatcagg tttttgtagt cggtcacaaa aatttagaca tggatgcttt
    22861 gggctctgct gtaggtatgc agttgttcgc cagcaatgtg attgaaaata gctatgctct
    22921 ttatgatgaa gaacaaatgt ctccagatat tgaacgagct gtttcattca tagaaaaaga
    22981 aggagttacg aagttgttgt ctgttaagga tgcaatgggg atggtgacca atcgttcttt
    23041 gttgattctt gtagaccatt caaagacagc cttaacatta tcaaaagaat tttatgattt
    23101 atttacccaa atcattgtta ttgaccacca tagaagggat caggattttc cagataatgc
    23161 ggttattact tatatcgaaa gtggtgcaag tagtgccagt gagttggtaa cggaattgat
    23221 tcagttccag aattctaaga aaaatcgttt gagtcgtatg caagcaagtg ttttgatggc
    23281 tggtatgatg ttggatacta aaaatttcac ctcgcgagta actagtcgga catttgatgt
    23341 tgctagctat ctcagaacgc gcggaagtga tagtattgct atccaggaaa tcgctgcgac
    23401 agattttgaa gaatatcgtg aggtcaatga acttatttta caggggtgta aattaggttc
    23461 agatgtacta atagcagagg ctaaggacac gaaatgctat gatacagttg ttattagtaa
    23521 ggcagcagat gccatgttag ccatgtcagg tattgaagcg agttttgttc ttgcgaagaa
    23581 tacacaagga tttatctcta tctcagctcg aagtcgtagt aaactgaatg tacaacggat
    23641 tatggaagag ttaggcggtg gaggccactt taatttggca gcagctcaaa ttaaagatgt
    23701 aaccttgtca gaagcaggtg aaaaactgac agaaattgta ttaaatgaaa taaaggaaaa
    23761 ggagaaagaa gaatgaaagt aatcttttta gcagatgtta aaggaaaagg taaaaaaggc
    23821 gaaattaagg aagtaccaac agggtatgcg caaaactttc ttatcaaaaa gaatctagcc
    23881 aaagaagcga ctgctcaagc tgtaggtgaa cttcgtggta aacaaaaatc ggaagaaaaa
    23941 gctcacgctg agatgattgc agaaggaaaa gcaattaaag cacaacttga agcagaagaa
    24001 actgttgtag aatttgttga aaaagttggt ccagatggtc gtacctttgg ttctattacc
    24061 aataagaaga ttgcagaaga attgcaaaag caatttggaa ttaagattga taaacgtcat
    24121 attcaagtac aagctccgat tcgagcggtt ggtttgattg atgtgccagt gaaaatctat
    24181 caagatatca caagtgtaat caatcttcgt gtgaaagaag gataagttta cactttcttg
    24241 acaagattgt aaaagaaggg aagtctgatg gcagaagtag aagagttacg agtacaacct
    24301 caagatatct tagctgagca atccgtttta ggggctatct ttattgatga gagtaaactt
    24361 gtttttgtgc gagaatacat tgagtctcgg gactttttta agtatgccca tcgtttgatt
    24421 ttccaagcca tggtcgattt atccgatcgt ggtgatgcca tagatgcaac aacggttcgt
    24481 actatccttg ataatcaagg tgatttacag aatattggtg gcttgtctta cttggttgag
    24541 attgttaatt ctgtgccaac ttctgctaat gcggagtatt atgctaagat tgttgcagaa
    24601 aaagcaatgc tacgtcgttt aattgccaag ttgacagagt ctgtcaacca agcttacgaa
    24661 gcgtcacaac cagctgatga aattattgct caggcagaaa aagggttgat tgatgtcagt
    24721 gaaaatgcaa atcgaagcgg gtttaagaac attcgagatg tgttgaatct caactttgga
    24781 aatctggaag ctcgctcgca acaaacgacc gatattacag gtattgcgac aggttatcgt
    24841 gatttggatc atatgacaac aggacttcat gaggaggagt tgattatctt agcagctcgt
    24901 ccagcagttg gtaagacagc atttgccttg aatatcgctc agaatattgg gactaagttg
    24961 gacaaaacgg ttgctatttt ttcactcgaa atgggtgcgg aaagcttggt agatcgtatg
    25021 ttagctgcag aaggcttagt ggagtcacat tctatccgta cagggcaatt gacagatgag
    25081 gagtggcaaa aatatactat tgctcagggt aatctagcta acgccagtat ctatatcgat
    25141 gatacgccag gtattcggat tacagagatt cgttctcgtt ctcgtaaatt ggctcaagaa
    25201 actggaaatc ttggtttgat tttgatagac tatttgcaac ttatcacggg aactggtcga
    25261 gaaaatcgtc aacaagaagt ttctgaaatt tctcgtcagt tgaaaatact agccaaggaa
    25321 ttgaaggttc cagtaatcgc tctgagtcag ctttctcgtg gtgtagaaca acgtcaggac
    25381 aagagaccgg tcttgtctga tattcgtgaa tctgggtcta ttgagcagga cgctgatatc
    25441 gtagcttttc tctatcgcga tgactactat gaacgtggtg gtgaagaaga ggagggtatc
    25501 ccaaataata aggtggaagt tattatcgag aaaaaccgta gtggagctcg tggaacagtg
    25561 gaattgattt tccaaaaaga atacaataaa ttttcaagta tctcaaagag ggaggcataa
    25621 gatgtcagat gcatttacag atgtagccaa gatgaaaaaa atcaaagaag aaatcaaggc
    25681 acatgaggga caagtcgtag aaatgacttt ggagaatggt cgtaagcgcc aaaaaaatag
    25741 attgggtaag ctaattgaag tttatccatc tctatttatt gtggagtttg gggatgtgga
    25801 aggagataaa caagttaatg tttacgttga atcctttact tactcagata ttcttacaga
    25861 aaagaatttg attcattatc ttgactaaag tgagaaattt tctcactttt tcttttttct
    25921 ccgaataatt taggtgaagg caatcatcgc tttatattat ttttcaagga ggaagaatga
    25981 aaattttacc gtttatagca agagggacaa gttattactt gaagatgtca gttaaaaagc
    26041 ttgttccttt tttagtagta ggattgatgc tagcagctgg tgatagtgtc tatgcctatt
    26101 ccggaggaaa tggatcgatt gcgcgtgggg atgattatcc tgcttattat aaaaatggga
    26161 gccaggagat tgatcagtgg cgcatgtatt ctcgtcagtg tacttctttt gtagcctttc
    26221 gtttgagtaa tgtcaatggt tttgaaattc cggcagctta tggaaatgcg aatgaatggg
    26281 gacatcgtgc tcgtcgggaa ggttatcgtg tagataatac accgacgatt ggttccatta
    26341 cttggtctac tgcaggaact tatggtcatg ttgcctgggt gtcaaatgta atgggagatc
    26401 agattgagat tgaggaatat aactatggtt atacagaatc ctataataaa cgagttataa
    26461 aagcaaacac gatgacagga tttattcatt ttaaagattt ggatggcggc agtgttggga
    26521 atagtcaatc ctcagcttca acaggcggaa ctcattattt taagaccaag tctgctatta
    26581 aaactgaacc cctagctagc ggaactgtga ttgattacta ttatcctggg gagaaggttc
    26641 attatgatca gatacttgaa aaagacggct ataagtggtt gagttatact gcctataatg
    26701 gaagctatcg ttatgttcaa ttggaggctg tgaataaaaa tcctctaggt aattctgttc
    26761 tttcttcaac aggtggaact cattatttta agaccaagtc tgctatcaaa actgaacccc
    26821 tagttagcgg aactgtgatt gattactatt atcctggaga gaaggttcat tatgatcaga
    26881 tacttgaaaa agacggctac aagtggttga gttatactgc ctataatgga agtcgtcgct
    26941 atatacagct agagggagtg acttcttcac aaaattatca gaatcaatca ggaaatatct
    27001 ctagctatgg atccaataat agttcaactg tcggttggaa gaaaataaat ggtagttggt
    27061 atcatttcaa atcaaatggt tctaaatcaa caggatggct gaaagacggt tctagctggt
    27121 attatttgaa attatctggt gaaatgcaga caggatggtt aaaggagaat ggctcgtggt
    27181 attatctggg tagttcaggg gcaatgaaaa caggctggta ccaggtctct ggtaagtggt
    27241 attattctta ctcttcaggc gccttagctg ttaatacgac ggtggatggc tacagagtaa
    27301 acagtgatgg agaacgagta tagaaaattg gagtaggaga aatttcctgc tcttttctgt
    27361 aagcagtttc cttgacattt ttcttatttt gcgctatcat atatacatat aatatatggg
    27421 agtctgtgta cagtctgaga ggaagtgtta aacttcgacc gcacctgatc tgggtaatgc
    27481 cagcggaggg aacgatactt agtctaattt tgcacctttt ccatgtatgg taaaggtttt
    27541 tcttttttta aaaaggaaaa cgagaagagg aggttcttat gaaagcaagc attgccttgc
    27601 aagttttacc cctagcacag gggattgatc ggatagctgt tattgatcag gtcattgctt
    27661 atctgcaaac tcaagaagtg acgatggtag tgacaccatt tgaaacggtc ttggaagggg
    27721 agtttgatga gcttatgcgc attctaaaag aagcgctgga agtggcaggg caggaggcag
    27781 acaatgtctt tgccaatgtc aaaataaatg taggagagat tttaagtatt gatgagaaac
    27841 ttgagaagta tactgagacg acacattagt ctattgggct ttctcggagt cttgttaatc
    27901 tggcagttag caggttttct taaacttctc cccaagttta tcctgccgac acctcttgaa
    27961 attctccagc cctttgttcg tgacagagaa tttctctggc accatagctg ggcgaccttg
    28021 agagtggctt tactggggct gattttggga gttttgattg cctgtcttat ggctgtgctc
    28081 atggatagtt tgacttggct caatgacctg atttacccta tgatggtggt cattcagacc
    28141 attccgacca ttgccatagc tcctatcctg gtcttgtggc taggttatgg gattttgccc
    28201 aagattgtct tgattatctt aacgacaacc tttcccatca tcgttagtat tttggacggt
    28261 tttaggcatt gcgacaagga tatgctgacc ttgtttagtc tgatgcgggc caagccttgg
    28321 caaatcctgt ggcattttaa aatcccagtt agcctgcctt acttttatgc aggtctgagg
    28381 gtcagtgtct cctacgcctt tatcacaact gtggtatctg agtggttggg aggttttgaa
    28441 ggtcttggtg tttatatgat tcagtctaaa aaattgtttc agtatgatac catgtttgcc
    28501 attattattc tggtgtcgat tatcagtctt ttgggtatga agctggtcga tatcagtgaa
    28561 aaatatgtga ttaaatggaa acgttcgtag aattagaatg tttctgaaaa agaaaagagg
    28621 aaatcaaaat gaagaaaaca tggaaagtgt ttttaacgct tgtaacagct cttgtagctg
    28681 ttgtgcttgt ggcctgtggt caaggaactg cttctaaaga caacaaagag gcagaactta
    28741 agaaggttga ctttatccta gactggacac caaataccaa ccacacaggg ctttatgttg
    28801 ccaaggaaaa aggttatttc aaagaagctg gagtggatgt tgatttgaaa ttgccaccag
    28861 aagaaagttc ttctgacttg gttatcaacg gaaaggcacc atttgcagtg tatttccaag
    28921 actacatggc taagaaattg gaaaaaggag caggaatcac tgccgttgca gctattgttg
    28981 aacacaatac atcaggaatc atctctcgta aatctgataa tgtaagcagt ccaaaagact
    29041 tggttggtaa gaaatatggg acatggaatg acccaactga acttgctatg ttgaaaacct
    29101 tggtagaatc tcaaggtgga gactttgaga aggttgaaaa agtaccaaat aacgactcaa
    29161 actcaatcac accgattgcc aatggcgtct ttgatactgc ttggatttac tacggttggg
    29221 atggtatcct tgctaaatct caaggtgtag atgctaactt catgtacttg aaagactatg
    29281 tcaaggagtt tgactactat tcaccagtta tcatcgcaaa caacgactat ctgaaagata
    29341 acaaagaaga agctcgcaaa gtcatccaag ccatcaaaaa aggctaccaa tatgccatgg
    29401 aacatccaga agaagctgca gatattctca tcaagaatgc acctgaactc aaggaaaaac
    29461 gtgactttgt catcgaatct caaaaatact tgtcaaaaga atacgcaagc gacaaggaaa
    29521 aatggggtca atttgacgca gctcgctgga atgctttcta caaatgggat aaagaaaatg
    29581 gtatccttaa agaagacttg acagacaaag gcttcaccaa cgaatttgtg aaataatgac
    29641 agaaattaga ctagagcacg tcagttatgc ctatggtcag gagaggattt tagaggatat
    29701 caatctacag gtgacttcag gcgaagtggt ttccatccta ggcccaagtg gtgttggaaa
    29761 gaccaccctc tttaatctaa tcgctgggat tttagaagtt cagtcaggga gaattgtcct
    29821 tgatggtgaa gaaaatccca aggggcgcgt gagttatatg ttgcaaaagg atctgctctt
    29881 ggagcacaag acggtgcttg gaaatatcat tctgcccctc ttgattcaaa aggtggataa
    29941 ggcagaagct atttcccgag cggataaaat tcttgcgacc ttccagctga cagctgtaag
    30001 agacaagtat cctcatgaac ttagcggtgg gatgcgccag cgtgtagcct tactccggac
    30061 ctaccttttt gggcacaagc tctttctctt agatgaggcc tttagcgcct tggatgagat
    30121 gacaaagatg gaactccacg cttggtatct tgagattcac aaacagttgc agctaacaac
    30181 tctgatcatc acgcatagta ttgaggaggc cctcaatctc agcgaccgca tctatatctt
    30241 gaaaaatcgc cctgggcaga ttgtttcaga aattaaacta gattggtctg aagatgagga
    30301 caaggaagtc caaaagattg cctacaaacg tcaaatcttg gcagaattag gcttagaata
    30361 agtagaaaaa tagggagttg gtgaagatta tcctttacca gcgccctttt tcttttaaaa
    30421 atgagaaaat ttcggtataa tagtcaaaca aggtcaaggt ttaaagagag aggtgggttt
    30481 gttatgagat ttaaaaatac atcggatcat attgaggcct acatcaaggc gattttagat
    30541 caatctggta tcgtggagtt gcaacggagt cagttggcag atacctttca ggttgttcct
    30601 agtcagatta actacgtgat caagacacgc tttacggaaa gtagaggcta cttggttgaa
    30661 agtaagcgtg gtggcggagg ctacattcgt ataggacgga ttgagttttc tagtcatcat
    30721 gaaatgctcc gggatctgct ttactcgatt ggtgagcgag tcagtcaaga aatttatgag
    30781 gatattctcc agcttttggt tgagcaggaa ttgatgacca agcaggagat gaatttgcta
    30841 gaatcagtag ctttggatcg cgttttagga gaagaagctc cagttgttcg agcaaacatg
    30901 ctacgtcagg tcatacaaga ggtagataga aaagggaagt aagatgaact attcaaaagc
    30961 attgaatgaa tgtatcgaaa gtgcctacat ggttgctgga cattttggag ctcgttatct
    31021 agagtcgtgg cacttgttga ttgccatgtc taatcacagt tatagtgtag caggggcaac
    31081 tttaaatgat tatccgtatg agatggaccg tttagaagag gtggctttgg aactgactga
    31141 aacggactat agccaggatg aaacctttac ggaattgccg ttctcccgtc gtttgcaggt
    31201 tctttttgat gaagcagagt atgtagcgtc agtggtccat gctaaggtac tagggacaga
    31261 gcacgtcctc tatgcgattt tgcatgatgg caatgccttg gcgactcgta tcttggagag
    31321 ggctggtttt tcttatgaag acaagaaaga tcaggtcaag attgctgccc ttcgtcgaaa
    31381 tttagaagaa cgtgcaggct ggactcgtga agatctcaag gctttacgcc aacgccatcg
    31441 tacagtagct gacaagcaaa attctatggc caatatgatg ggcatgccgc agactcctag
    31501 tggtggtctc gaggactata cgcatgattt gacagagcaa gcgcgttctg gcaagttaga
    31561 accagtcatc ggtcgggaca aggaaatctc acgtatgatt caaatcttga gccgtaagac
    31621 taagaacaac cctgtcttgg ttggggatgc tggtgtcggg aaaacagctc tggcccttgg
    31681 tcttgcccag cgtattgcta gtggtgacgt gcctgcggaa atggctaaga tgcgcgtgtt
    31741 agaacttgat ttgatgaatg tcgttgcagg gacacgcttc cgtggtgact ttgaagaacg
    31801 catgaataat atcatcaagg atattgaaga agatggccaa gtcatcctct ttatcgatga
    31861 actccacacc atcatgggtt ctggtagcgg gattgattcg actctggatg cggccaatat
    31921 cttgaaacca gccttggcgc gtggaacttt gagaacggtt ggtgccacta ctcaggaaga
    31981 atatcaaaaa catatcgaaa aagatgcggc actttctcgt cgtttcgcta aagtgacgat
    32041 tgaagaacca agtgtggcag atagtatgac tattttacaa ggtttgaagg cgacttatga
    32101 gaaacatcac cgtgtacaaa tcacagatga agcggttgaa acagcggtta agatggctca
    32161 tcgttattta accagtcgtc acttgccaga ctctgctatc gacctcttgg acgaagcagc
    32221 agcaacagtg caaaataagg caaagcatgt aaaagcagac gattcagatt tgagtccagc
    32281 tgacaaggcc ctgatggatg gcaagtggaa acaggcagcc cagctaatcg caaaagaaga
    32341 ggaagtacct gtctacaaag acttggtgac agagtctgat attttgacca ccttgagtcg
    32401 cttgtcagga atcccagttc aaaagctgac tcagactgac gctaagaaat atctaaatct
    32461 tgaagcagaa ctccataaac gggttatcgg tcaagatcaa gctgtttcaa gtattagtcg
    32521 tgcgattcgc cgtaatcagt caggaattcg cagtcacaag cgtccgatcg gttcctttat
    32581 gttcctagga cccacaggtg tcggtaagac cgagttggcc aaggctttgg cagaagttct
    32641 ctttgatgac gaatcagccc ttatccgctt tgatatgagt gagtatatgg agaaattcgc
    32701 agccagccgt ctaaatggag ctcctccagg ctatgtgggt tacgaagaag gtggggagtt
    32761 gacagagaag gttcgcaata aaccctattc cgttctcctc tttgatgagg tagagaaggc
    32821 tcacccagat atctttaatg ttctcttgca ggttctggat gacggtgtct tgacagatag
    32881 caagggacgc aaggtcgatt tttcaaatac cattatcatt atgacatcga acctaggtgc
    32941 gactgccctt cgtgatgata agactgttgg ttttggggct aaggatattc gttttgacca
    33001 ggaaaatatg gaaaaacgca tgtttgaaga actgaaaaaa gcttatagac cggaattcat
    33061 caaccgtatt gatgagaagg tggtcttcca tagcctatct agtgatcata tgcaggaagt
    33121 ggtgaagatt atggtcaagc ctttagtggc aagtttggct gaaaaaggca ttgacttgaa
    33181 attacaagct tcagctctga aattgttagc aaatcaagga tatgacccag agatgggagc
    33241 tcgcccactt cgcagaaccc tgcaaacaga agtggaggac aagttggcag aacttcttct
    33301 caagggagat ttagtggcag gcagcacact taagattggt gtcaaagcag gccagttaaa
    33361 atttgatatt gcataaaaga ataaaagtac cagcatctga ccataagtca cagtggagtg
    33421 aaactcaatg aaaatcaaag agcaaactag gcagctagcc gcaggttgct caaaacactg
    33481 ttttgaggtt gcagatagag ctgacgtggt ttgaagagat tttcgaagag tataagctgc
    33541 aagatgaatg attttcttgt attgacgttg ttgttgacaa aaagtagcgg ataaatgaaa
    33601 tccattctat tatcatagat gataggctgg taggaaattt tcaaatagca tacaggaaat
    33661 agatgtatgg agttctggta gtagaaaggg agagagatga acattttagt tgcagatgac
    33721 gaggaaatga ttagagaagg aattgcagca tttctgacag aagagggtta tcatgtcatt
    33781 atggctaagg atggacaaga ggtcttggaa aaatttcaag atctccctat ccatctcatg
    33841 gtactggatt taatgatgcc taggaagagt ggttttgaag tgttaaaaga aatcaatcaa
    33901 aagcacgata ttcctgtcat cgtcttgagt gctctgggag atgaaattac tcagtcacag
    33961 gtatttgatc tctatgctga tgatcatgtg acaaaacctt tttctttggt actgcttgtc
    34021 aagcgtatta aggcgcttat cagacgttac tacgtcatag aggatatttg gcgatatcag
    34081 gatgtaacag tggattttac ctcttacaaa gcacattata aaaatgaaga aattgatctc
    34141 aaaccaaagg aattactggt actaaagtgt ttgattcagc ataaaaatca agttttaagt
    34201 agagagcaga tattggaaga aatttcaaaa gatgtagctg atttaccttg tgatagggtc
    34261 gttgatgtct atattcgtac tcttcgcaaa aaattagctt tagattgtat cgtgactgtg
    34321 aaaaatgttg ggtataagat tagtttatga taaaaaatcc taaattatta accaagtcct
    34381 ttttaagaag ttttgcaatt ctaggtggtg ttggtctagt cattcatata gctatttatt
    34441 tgacctttcc tttttattat attcaactgg agggggaaaa gtttaatgag agcgcaagag
    34501 tgtttacgga gtatttaaag actaagacat ctgatgaaat tccaagctta ctccagtctt
    34561 attcaaagtc cttgaccata tctgctcacc ttaaaagaga tattgtagat aagcggctcc
    34621 ctcttgtgca tgacttggat attaaagatg gaaagctatc aaattatatc gtgatgttag
    34681 atatgtctgt tagtacagca gatggtaaac aggtaacagt gcaatttgtt cacggggtgg
    34741 atgtctacaa agaagcaaag aatattttgc ttttgtatct cccatataca tttttggtta
    34801 caattgcttt ttcctttgtt ttttcttatt tttatactaa acgcttgctc aatcctcttt
    34861 tttacatttc agaagtgact agtaaaatgc aagatttgga tgacaatatt cgttttgatg
    34921 aaagtaggaa agatgaagtt ggtgaagttg gaaaacagat taatggtatg tatgagcact
    34981 tgttgaaggt tatttatgag ttggaaagtc gtaatgagca aattgtaaaa ttgcaaaatc
    35041 aaaaggtttc ctttgtccgc ggagcatcac atgagttgaa aaccccttta gccagtctta
    35101 gaattatcct agagaatatg cagcataata ttggagatta caaagatcat ccaaaatata
    35161 ttgcaaagag tataaataag attgaccaga tgagccactt attggaagaa gtactggagt
    35221 cttctaaatt ccaagagtgg acagagtgtc gtgagacttt gactgttaag ccagttttag
    35281 tagatatttt atcacgttat caagaattag ctcattcaat aggtgttaca attgaaaatc
    35341 aattgacaga tgctaccaga gtcgtcatga gtcttagggc attggataag gttttgacaa
    35401 acctgattag taatgcaatt aaatattcag ataaaaatgg gcgcgtaatc atatccgagc
    35461 aagatggcta tctctctatc aaaaatacat gtgcgcctct aagtgaccaa gaactagaac
    35521 atttatttga tatattttat cattctcaaa tcgtgacaga taaggatgaa agttccggtt
    35581 tgggtcttta cattgtgaat aatattttag aaagctatca aatggattat agttttctcc
    35641 cttatgaaca cggtatggaa tttaagatta gcttgtagac agattagttt tttattaaag
    35701 ttcatatagg gttaacataa gtgtgttatt ctttgtgtag ataaaagaaa ggatactaat
    35761 atggtattag cgattatttt agtaacattc tttattcgat tgattttttt aaagcgttcg
    35821 atagagaatg agaaacgaat ccttagcaat ggcgggaaag aatttggagt tgagaataca
    35881 aaacgattaa ctatggctca tattgttttt tatctctctt gcttggttga ggcaatggtg
    35941 cacaagacaa tttttgatgg catgggcatg gttggtttag tcttgcttat tttttctatg
    36001 ctgatgttga tgttggtgat tcacttgttg ggagatattt ggacagtgaa gcttatgctt
    36061 gtcaataatc acaaatatgt agatcatatc ttgtttagga cagtaaaaca ccctaattac
    36121 tttttaaata ttttacctga gttgattggc ttgaccttgt tgagtcatgc ctatatgact
    36181 tttgttttag tttttccagt ttatgcagtt attttgtatc gacgaatagc tgaagaggaa
    36241 aagctattac atgaagttat aatcccaaat ggaagcataa agagataaat acaaaattcg
    36301 actcatatac agttcatatt gaagtgatat agtaaggtta aagaaaaaat atagaaggaa
    36361 ataaacatgt ttgcatcaaa aagcgaaaga aaagtacatt attcaattcg taaatttagt
    36421 attggagtag ctagtgtagt agttgccagc ttgttcttag gaggagtagt ccatgcagaa
    36481 ggggttagga gtaagaataa cctcacggtt acatctagtg ggcaagatat atcgaagaag
    36541 tatgctgatg aagtcgagtc gcatctacaa agtatattga aggatgtcaa taaaaatttg
    36601 aaaaaagttc aacataccca aaatgtcgac ttcaacaaaa agttgagcag aattaaaacg
    36661 aagtatttgt atggattaaa agagaagtcg gaagctgagt tgacgttaaa aacaaaagaa
    36721 acaaaagaag agttaaccgc agcttttgag cagtttaaaa aagatacatt gaaatcagga
    36781 aaaaaggtag cagaagctga gaaaaaagcc aaagctcaaa aagaagaaga tcgccgtaac
    36841 tacccaacca atacttacaa aacaatcgaa ctggaaattg cggaagcaga agtaggggtc
    36901 gccaaggcag agcttgagct tgagtttgca caagctcaag ttcaaatacc tcaagatact
    36961 gagaaaatta atgctgctaa atctaaagta gaagctgcta aaagtaatgt taaaaaacta
    37021 gaaaaaatta aatcagatat tgaaaaaacg tatttgtata aattagataa ctcaaccaaa
    37081 gaaacgccaa aacctagagt gcgaagaaat tctccggaaa taaaagctaa gggcagagtc
    37141 aaaaattatg aagaggctaa tattgaactt tctaaatata tgactgattt gtataaatta
    37201 gataactcaa ccaaagaaac gccaaaatct agagtgcgaa gaaattctcc gcaagtaggc
    37261 gattcgagag aacttaagga aacgatagac aaagcgaaag aaactctgtc tacctatatg
    37321 gtaactcgtt taacgaagct ggatccatct gttttttggt ttgcagatct tcttatggat
    37381 gctaagaagg ttgtggaaga atacaagaca aaattagagg atgcttcaga taaaaaatcg
    37441 gtagaagact tgcgaaagga agcagaagga aaaatagagt ctcttatcgt gactcaccaa
    37501 aatagagaaa aagaaaacca accagcaccc caaccaggag gacaagcagg tggttcaatg
    37561 gttgtaccac cggtgacgca aacacctcca tcaacttccc aaagtccagg acaaaaggcg
    37621 accgaagctg aaaagaaaaa gttacaagac ttgattcgtc aattccaaga agccttgaac
    37681 aaactagacg atgaaacaaa gactgttcca gatggggcta aactcacagg agaagctgga
    37741 aaagcctata atgagactag aacttatgcg aaagaagttg ttgacaaaag caagaagctt
    37801 ctatcacaga cagcagtgac aatggatgaa ttggcaatgc aattaaccaa attgaacgat
    37861 gccatgtcta aattgaaaga agctaaagcg aaattggtac cagaggttaa accacagccg
    37921 gaaaacccag agccaaaacc acaaccagag ggtgagaaac caagcgtacc agatattaat
    37981 caggagaaag aaaaagctaa acttgctata gcaacataca tgagcaagat tttagatgat
    38041 ataaagaaac atcatctgaa gaaagaaaaa catcatcaga ttgttgctct tattaaggac
    38101 cttgataaac ttaaaaagca agcactttct gaaattgata atgtaaatac caaagtagaa
    38161 attgagaata cagtccacaa ggtatttgca gacatggata cggttgttac taaattccaa
    38221 aaaggcttaa ttcag
//
LOCUS       DAVLZG010000013        37468 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLZG010000013 DAVLZG010000000
VERSION     DAVLZG010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.013"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            206..913
                     /locus_tag="VYO72_000637"
     CDS             206..913
                     /locus_tag="VYO72_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1707053.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLHKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            918..1940
                     /locus_tag="VYO72_000638"
     CDS             918..1940
                     /locus_tag="VYO72_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1707054.1"
                     /translation="MINQIYQLTKPKFINVKYQEEVIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            1957..2826
                     /gene="licA"
                     /locus_tag="VYO72_000639"
     CDS             1957..2826
                     /gene="licA"
                     /locus_tag="VYO72_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1707055.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIEFAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            2816..3694
                     /locus_tag="VYO72_000640"
     CDS             2816..3694
                     /locus_tag="VYO72_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1707056.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            3706..4395
                     /locus_tag="VYO72_000641"
     CDS             3706..4395
                     /locus_tag="VYO72_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1707057.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEIFKNEN"
     gene            4491..5339
                     /gene="dprA"
                     /locus_tag="VYO72_000642"
     CDS             4491..5339
                     /gene="dprA"
                     /locus_tag="VYO72_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1707058.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            6223..7266
                     /locus_tag="VYO72_000643"
     CDS             6223..7266
                     /locus_tag="VYO72_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1707059.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            7433..9520
                     /gene="topA"
                     /locus_tag="VYO72_000644"
     CDS             7433..9520
                     /gene="topA"
                     /locus_tag="VYO72_000644"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1707060.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            9626..9985
                     /locus_tag="VYO72_000645"
     CDS             9626..9985
                     /locus_tag="VYO72_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1707061.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            10078..10710
                     /locus_tag="VYO72_000646"
     CDS             10078..10710
                     /locus_tag="VYO72_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1707062.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            10754..11410
                     /locus_tag="VYO72_000647"
     CDS             10754..11410
                     /locus_tag="VYO72_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1707063.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            11429..12523
                     /locus_tag="VYO72_000648"
     CDS             11429..12523
                     /locus_tag="VYO72_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1707064.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEETINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLTETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQERVLVTVENRDTETILNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            12535..13561
                     /gene="leuB"
                     /locus_tag="VYO72_000649"
                     /pseudo
     CDS             12535..13561
                     /gene="leuB"
                     /locus_tag="VYO72_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            13558..13827
                     /locus_tag="VYO72_000650"
     CDS             13558..13827
                     /locus_tag="VYO72_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1707065.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            13831..14190
                     /gene="leuD"
                     /locus_tag="VYO72_000651"
     CDS             13831..14190
                     /gene="leuD"
                     /locus_tag="VYO72_000651"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1707066.1"
                     /translation="MVGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            14352..14975
                     /locus_tag="VYO72_000652"
                     /pseudo
     CDS             14352..14975
                     /locus_tag="VYO72_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            15141..17072
                     /locus_tag="VYO72_000653"
     CDS             15141..17072
                     /locus_tag="VYO72_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1707067.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            17059..18375
                     /locus_tag="VYO72_000654"
     CDS             17059..18375
                     /locus_tag="VYO72_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1707068.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            18550..19536
                     /locus_tag="VYO72_000655"
     CDS             18550..19536
                     /locus_tag="VYO72_000655"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1707069.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            19600..19671
                     /locus_tag="VYO72_000656"
     tRNA            19600..19671
                     /locus_tag="VYO72_000656"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19633..19635,aa:Arg,seq:ccg)
     gene            19854..20552
                     /locus_tag="VYO72_000657"
     CDS             19854..20552
                     /locus_tag="VYO72_000657"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1707070.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            20543..24082
                     /gene="smc"
                     /locus_tag="VYO72_000658"
     CDS             20543..24082
                     /gene="smc"
                     /locus_tag="VYO72_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1707071.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENACKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIVIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            24079..24873
                     /locus_tag="VYO72_000659"
     CDS             24079..24873
                     /locus_tag="VYO72_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1707072.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            24873..25691
                     /locus_tag="VYO72_000660"
     CDS             24873..25691
                     /locus_tag="VYO72_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1707073.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVSEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            25695..26972
                     /gene="ftsY"
                     /locus_tag="VYO72_000661"
     CDS             25695..26972
                     /gene="ftsY"
                     /locus_tag="VYO72_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1707074.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(27016..28503)
                     /locus_tag="VYO72_000662"
     CDS             complement(27016..28503)
                     /locus_tag="VYO72_000662"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1707075.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(28652..29392)
                     /locus_tag="VYO72_000663"
     CDS             complement(28652..29392)
                     /locus_tag="VYO72_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1707076.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(29392..31557)
                     /locus_tag="VYO72_000664"
     CDS             complement(29392..31557)
                     /locus_tag="VYO72_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1707077.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            31730..32683
                     /locus_tag="VYO72_000665"
     CDS             31730..32683
                     /locus_tag="VYO72_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707078.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            32760..34748
                     /gene="uvrB"
                     /locus_tag="VYO72_000666"
     CDS             32760..34748
                     /gene="uvrB"
                     /locus_tag="VYO72_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1707079.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            34758..35321
                     /locus_tag="VYO72_000667"
     CDS             34758..35321
                     /locus_tag="VYO72_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707080.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            35287..35796
                     /locus_tag="VYO72_000668"
     CDS             35287..35796
                     /locus_tag="VYO72_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707081.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            35849..36316
                     /locus_tag="VYO72_000669"
     CDS             35849..36316
                     /locus_tag="VYO72_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1707082.1"
                     /translation="MSRSQLTILTNICLIEDLETQCVVMQYRAPETNRWSGYAFPGGH
                     VENGEAFAESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYKATEFTGTLQS
                     SDEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(36313..36828)
                     /locus_tag="VYO72_000670"
     CDS             complement(36313..36828)
                     /locus_tag="VYO72_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1707083.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHQVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(36840..37367)
                     /locus_tag="VYO72_000671"
     CDS             complement(36840..37367)
                     /locus_tag="VYO72_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1707084.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        11593 a         6585 c         8243 g        11047 t
ORIGIN      
        1 aaggactcta aaatttcgca gccatttatt agtaattgct acagaattcc tagtcattac
       61 tagaaatgaa ctagtttctt tgaataatag aactgcataa ttctcctatt ctagaagggg
      121 aggaccagta tttcttttat gataggacta gattgtggta taatagagag aataagtttt
      181 tttagtaaga caaaggagaa aatagatgat ttatgcagga attcttgccg gtggaactgg
      241 cacacgcatg ggaatcagta acttgccaaa acaattttta gagctaggtg atcgacctat
      301 tttgattcat acaattgaaa aatttgtctt ggagccaagt attgaaaaaa ttgtagttgg
      361 ggttcatgga gactgggttt ctcatgcaga agatcttgta gataaatatc ttcctcttca
      421 caaggaacgt atcatcatta caaagggtgg tgctgaccgc aatacaagta ttgagaaaat
      481 cattgaagcc attgatgctt atcgtccgct tacttcagag gatatcgttg ttacccacga
      541 ttctgttcgt ccatttatta cacttcgcat gattcaggac aatatccaac ttgcccaaaa
      601 tcatgacgca gtggacacag tggtagaagc ggttgatact atcgttgaaa gtaccaatgg
      661 tcaatttatt acagatattc caaatcgtgc tcacctttat caaggacaaa cacctcaaac
      721 attccgttgc aaggacttca tggaccttta tggatctctt tctgatgaag agaaggaaat
      781 cttgacagat gcatgtaaaa tctttgtgat caaaggaaaa gatgtggcct tggccaaagg
      841 tgaatactca aatctgaaga ttacaaccgt aacagatttg aagattgcaa aaagtatgat
      901 tgagaaagac tagtaaaatg attaatcaaa tttatcaact aactaagcct aagtttatca
      961 atgtcaaata tcaggaagag gttattgacc aagagaatca tatccttatc cgtcccaact
     1021 acatggctgt ctgtcatgcg gatcagcgtt actatcaggg aaaacgtgat cccaagattt
     1081 tgaataaaaa gcttccaatg gcaatgattc acgagtcatg tggaaccgtc atttctgacc
     1141 cgaccggaac ctacgaggtt ggtcaaaaag ttgtcatgat tcccaatcag tctcctatgc
     1201 agagtgatga agaattctat gaaaactaca tgacagggac ccatttcttg tctagtggat
     1261 ttgatggctt tatgagagag tttgtttctc tccctaaaga tcgtgtggtg gcttatgatg
     1321 ctattgaaga tacggttgca gccattacag agtttgtcag tgtgggcatg cacgctatga
     1381 atcgtctatt gactcttgct catagcaagc gggagcggat cgccgttatt ggagatggaa
     1441 gtttagcttt tgtggttgcc aatattatca actatacttt gccagaagca gagattgtgg
     1501 ttattggtcg tcattgggaa aagttggaac tcttctcatt tgccaaagaa tgctatatta
     1561 cggataatat tcctgaagat ttggcctttg accatgcttt tgaatgttgt ggtggtgatg
     1621 gtactggacc agctattaat gacttgattc gctacattcg tcctcaggga acgattctca
     1681 tgatgggagt tagcgaatat aaagtcaatc tcaatactcg cgatgcctta gaaaagggct
     1741 tgattttggt tgggtcatct cgttctggtc gcattgattt tgaaaatgct atccaaatga
     1801 tggaagtcaa gaaatttgcc aatcgtctta aaaatatcct ttatctagaa gaacctgtaa
     1861 gagaaattaa agatattcat cgtgtctttg caaccgattt aaacacagcc tttaaaacag
     1921 tgtttaagtg ggaagtataa gtactggagg ttaattgtgg agaaaatcat taaagaaaaa
     1981 atttcttcct tacttagtca agaagaggaa gtcctcagtg ttgaacaact gggtggaatg
     2041 accaatcaaa actatttggc caaaacaaca aataagcaat acattgttaa attctttggt
     2101 aaagggacag aaaagcttat caatcgacaa gatgaaaagt acaatcttga actactaaag
     2161 gatttaggct tagatgtaaa aaattatctt tttgatattg aagctggtat caaagtaaat
     2221 gagtatatcg aatttgcgat tacgcttgat tcaacgtcaa tcaagaccaa gttcgacaaa
     2281 attgctccaa tattacaaac tattcatacg tctgctaagg aattaagagg agaatttgct
     2341 ccttttgaag aaatcaaaaa atacgaatcc ttgattgaag aacaaattcc ttatgccaac
     2401 tatgaatctg ttagaaatgc agtcttctcc ttagagaaaa gactggctga cttaggtgtt
     2461 gacagaaaat cttgtcatat cgatttggtg cctgaaaact ttatcgaatc acctcaagga
     2521 cgactttatt tgattgactg ggaatattca tcaatgaatg atccaatgtg ggatttggct
     2581 gccctctttt tagagtctga attcacttcc caagaggaag aaactttctt atctcactat
     2641 gagagtgacc aaacaccggt ttctcatgaa aagattgcta tttataaaat tttacaagat
     2701 actatttgga gtctatggac tgtctataag gaagagcaag gtgaagattt tggtgactat
     2761 ggtgtgaatc gttaccaaag agctgttaaa ggtttggctt cttatggagg ttcagatgaa
     2821 aagtaaaaac ggagttcctt ttggccttct ctcaggtatt ttctggggct tgggtctaac
     2881 ggttagtgct tatatctttt cgatttttac agatttgtca ccctttgtgg tggctgcagc
     2941 tcatgatttt ttgagcatct ttatcttact agcttttctc ttggtaaaag aagggaaagt
     3001 tcgcctctca attttcttaa atattcgcaa tgtcagtgtt atcatcggag ccttgctagc
     3061 aggccctatc ggtatgcagg ccaatcttta tgcagttaag tatatcggaa gttctttagc
     3121 ttcatctgta tcggctattt accctgcgat ttcagttcta ttggctttct tctttttgaa
     3181 gcacaagatt tcgaaaaata ctgtatttgg gattgtcttg attattggag ggattattgc
     3241 tcagacctat aaggttgaac aggttaattc tttctacatt gggattcttt gtgctttggt
     3301 ttgtgctatt gcatggggaa gtgagagtgt tcttagctct tttgccatgg aaagtgaatt
     3361 gagtgaaatc gaagccctct taatccgtca agtaacttcg ttcttgtcct atcttgtgat
     3421 tgtgctcttc tctcatcagt catttactgc agtagccaat ggacaattgc taggtctcat
     3481 gattgttttt gcagcctttg atatgatttc ctacttggct tattatatcg ctatcaatcg
     3541 cttgcaacca gccaaggcta caggcttgaa cgtgagctat gtagtatgga cggtcttgtt
     3601 tgcagttgtt ttcttgggtg caccgctaga tatgctgacc attatgacgt cacttgtcgt
     3661 cattgctgga gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa agccattatc
     3721 ttagcagcgg gattgggaac tcgcttgcgt cctatgactg aaaatacccc taaagccttg
     3781 gttcaggtta atcaaaaacc cttaattgag taccaaattg agtttctcaa agaaaaagga
     3841 atcaatgaca tcatcatcat tgttggttat cttaaagaac aattcgatta cttaaaagaa
     3901 aaatacggtg ttcgcctcgt tttcaatgat aaatacgctg actacaataa cttttactct
     3961 ctctatcttg taaaagaaga attggccaac agctatgtta ttgatgctga caattatctc
     4021 tttaaaaata tgttccgcaa tgatttgact cgttcgactt attttagtgt ttatcgtgaa
     4081 gattgtacca acgaatggtt cttggtctat ggagatgact acaaggttca agacattatt
     4141 gttgatagca aggcaggtcg catccttagt ggtgtatcct tctgggatgc tccaactgca
     4201 gaaaagattg tcagctttat cgataaggct tatgcaagtg gcgaatttgt tgatctctat
     4261 tgggacaata tggttaagga taatatcaaa gagctagatg tctatgttga agaattagaa
     4321 ggcaatagca tttatgagat cgatagtgtc caagactatc gtaaattaga agaaattttt
     4381 aaaaacgaaa attaaagatt ccaacatctg acaaaatagt cggatgtttt ttgatttttt
     4441 acgaactttt acgaatagat agatgagtag aaaaagaaat ggagttattt atgaaaatca
     4501 caaactatga aatctataag ttaaaaaaat caagtttgac caatcaacag attttgaaag
     4561 ttctagaata cggtgaaaat gttgatcagg agcttttgtt gggtgatatt gcagatatat
     4621 caggttgccg taatccagcc gtttttatgg aacgttattt tcagatagac gatgcgcatt
     4681 tgtcgaaaga gtttcaaaaa tttccatctt tctctatttt agatgactgt tatccttggg
     4741 atttgagtga aatatatgat gcgcctgtac ttttatttta caagggaaat cttgacctcc
     4801 tgaaattccc gaaggtagcg gtcgtgggca gtcgtgcttg tagcaaacag ggagctaagt
     4861 cagttgaaaa agtcattcaa ggcttggaaa atgaactggt tattgtcagt ggtctggcca
     4921 agggcattga cacagcagct catatggcag ctcttcagaa tggcggaaaa accattgcag
     4981 tgattggaac aggactggat gtgttttatc ctaaagccaa taaacgcttg caagactaca
     5041 tcggcaatga ccatctggtt ctaagtgaat atggacctgg cgaacaacct ctgaaatttc
     5101 attttcctgc ccgtaatcgc atcattgctg gactttgtcg tggtgtgatt gtagcagagg
     5161 ctaagatgcg ttcaggtagt ctcattacgt gtgagcgagc aatggaagaa ggacgcgatg
     5221 tctttgctat tcctgatagc attttagatg gactatcaga cggttgccat catttgattc
     5281 aagaaggagc aaaattggtc accagtgggc aagatgttct tgcggaattt gaattttaaa
     5341 aatgacctaa gctagaattc taagaaaaaa tcaattttaa gagaaaatga acccaacatt
     5401 tccataataa aacgcatatt agcaagtttt taacacttga taatatgcgt tttttctaag
     5461 tggattagta gagtagagga tttttctcat ataatactct tcgaaaatct cttcaaacta
     5521 cgtcagcttc catctgcaac ctcaaaacag tattttgagc tgacttcgtc agtcttatct
     5581 acaacctcaa agcagtgctt tgagcaacct gtggctagct tcctagtttg cgctttgatt
     5641 ttcattgagt ataagggaaa gtatagtgaa ttgaaataag atgtgaacaa ctctatcagg
     5701 aaagtcaaat taatttatag aaatatttta gcagccaagg tgcactgtta tagattcaat
     5761 acactataat ttagtgtaat tgagaaagga gaaatgattg tgattgatgt tggctaggtt
     5821 atgttcaatg attcctaccg tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa
     5881 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
     5941 tggttattat aagaaatggt ctaaaataga tgatgatact tttcgaaaat ctttttacgt
     6001 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
     6061 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catttgagtc aggatattat
     6121 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
     6181 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
     6241 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
     6301 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
     6361 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
     6421 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
     6481 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
     6541 gctagttcgg agattgttgc tagaacctct ccgactattt gggatgttct cattgctttt
     6601 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
     6661 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
     6721 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
     6781 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
     6841 gataacgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     6901 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     6961 aagaaattta tatcagagca gtttcagggg tataatattt tgaaaaaaac ctattctaaa
     7021 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     7081 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     7141 ttgtctgatt cagaacaact tagtaaggaa gagctggtgg agtatttctt ccagtatatc
     7201 aaggataagg aagcaaaaga aaaggagaaa gccaataaat ttgatacaga gtctgaggag
     7261 caataatttc ttgagaatag ctggtttctc tcgtgagtct tctatgtata tcaaaggaag
     7321 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     7381 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     7441 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     7501 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     7561 gcatatccgt gatttgaaga aatccagtat gtccgtcgat attgaaaata attatgaacc
     7621 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     7681 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     7741 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     7801 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     7861 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     7921 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     7981 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     8041 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     8101 tggtaaaaag atgaaactga ccagcaataa cgaagtcaag gaagtcttgt ctcgtctgac
     8161 gagtaaagac ttttcagtag atcaggtgga taagaaagag cgtaagcgca atgctccttt
     8221 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     8281 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     8341 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     8401 ggcggcaagc ttcattacgg atcgttttgg tagcaagtat tctaagcacg gtagcaaggt
     8461 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcga gtgtctttaa
     8521 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     8581 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     8641 attgtctcaa aatggagttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     8701 tcttgccatt tataatgatt ctgacaagaa taaaatgcta ccagatatgg ctgttggaga
     8761 tgtggtcaaa caggttaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     8821 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     8881 tgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     8941 tgaaccgaca gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat
     9001 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     9061 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     9121 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     9181 agtgtgtggc agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     9241 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     9301 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc ttttctatgg
     9361 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     9421 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     9481 ttgtagcaaa ggcgactacg aggaagaaaa gattaaataa gaggaggggc ccgaaagtaa
     9541 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     9601 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     9661 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     9721 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     9781 caagctctat caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg
     9841 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     9901 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcactt attatctttt
     9961 caaggtcatt ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa
    10021 agcatattca taataatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
    10081 atttacgaat tttgtgctga aaatgtgact ttacttgaaa aagcgatgca ggctggagct
    10141 cgtcggattg aactctgtga taatctagca gttggtggga caacacccag ctatggagtg
    10201 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
    10261 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
    10321 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gaactttaac tgctgataaa
    10381 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
    10441 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
    10501 agtcaagccg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
    10561 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
    10621 ccaggtgggg ggattgacct tgaaaaccgt caaaccttta tcgaccaggt gggggtaaca
    10681 caattgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
    10741 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
    10801 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
    10861 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
    10921 agagactggt gacctctatc ctcacgttca tatggaaagc atgaggggaa gttttgtcgg
    10981 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
    11041 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
    11101 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
    11161 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
    11221 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca
    11281 aaaggggatt tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga
    11341 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
    11401 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
    11461 gaagaaattt tcagaaaata taggatttac cacaccagag gaatatggtg ccatcttcaa
    11521 atacctgatt gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga
    11581 tgacctcgga atagcagtgg caaatagcct tgctgctgtc aagaatggtg caggacgtgt
    11641 tgaagagact atcaatggta ttagggagcg agctggaaat gctgctttgg aagaaattgc
    11701 agtggctctc aatattcgcc aagattacta ccaagtagaa accagtattg tcctaactga
    11761 gaccatcaat acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa
    11821 agccgtcgtt ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct
    11881 taaaaatcct ctcacttatg agatcatcac acctgaattg gttggtgtta agattccgct
    11941 tggaaaatta tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt
    12001 tacagaagag gatatcaaac cactctttgc taagttcaag gcactggtcg ataagaagca
    12061 agaaatcaca gatgcagata ttcgagcttt ggtagctgga accatggttg aaaatccaga
    12121 aggcttccac tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct
    12181 cgttagccta gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc
    12241 cgttgaagca atctttaatg ctatcgataa gttctttaac caatctgttc gtttggtgtc
    12301 ctacactatc gatgcggtaa cagatggaat cgatacccag gaacgggttt tggtcactgt
    12361 tgaaaacaga gatacagaaa ccatcttgaa tgcagcaggg cttgattttg atgtgttgaa
    12421 ggcttctgct attgcctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga
    12481 gatgggacgc agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca
    12541 aagaaaatag tagctctagc aggagacgga attggcccag aaatcatgga ggctggttta
    12601 gaagttctgg aggctctagc tgaaaaaaca ggttttgact atgagatcgt tcggaggtgc
    12661 agatattgat gcagcaggat ctcccttacc tgatgaaacc cttaaggcaa gtagggaagc
    12721 agatgctatc ctactagtag ctatcggtag tcctcagtat gatggagtag cggttcgccc
    12781 tgaacaaggc ctgatggctc tccgtaagga actcaatctt tacgctaata ttcgtcctgt
    12841 aaaaatcttt gacagtctca agtatttgtc accactcaaa ccggaacgaa tttctggtgt
    12901 agactttgtc gtggtgcgtg aattgacagg cgagatttac tttggagatc atattcttga
    12961 agagcgcaaa gcgcgtgata tcaacgacta tagctatgag gaagtggagc ggattattcg
    13021 caaagccttt gaaattgcaa gaaatcgcag aaaaatcgtt actagtatcg ataagcaaaa
    13081 tgttctagcg acctcaaaac tctggcggaa agtagctgag gaagtcgcac aggatttccc
    13141 agatgtaacc ttggaacacc agctggtaga ctcagctgct atgcttatga ttaccaatcc
    13201 tgctaagttt gatgttattg taacggagaa tctttttgga gatattttat ctgatgaatc
    13261 aagcgtctta tctggtacac ttgaggttat gccatcagcc agtcattctg aaaatggacc
    13321 aagtctctat gaacctattc acggttcagc acctgatatt gcaggtcaag gaattgccaa
    13381 tcctatttcc atgattttat tagttgtcat gatgttgaga gatagtttcg gacgttatga
    13441 ggatacagag cgtatcaaac gtgctgttga gacaagtctg gcggcaggaa ttttaacgag
    13501 agatatagga ggtcaggctt caacaaagga aatgatggaa gctattattg caaggttatg
    13561 aagttagacg aaaaaattac tctagtcctt ttgatttgga atgtcatcat tttcttgatt
    13621 tatggcattg acaaattcaa ggcaagaaga agagcttggc gcatcccaga gaaaatctta
    13681 ctcattttag cccttacttg tggtggtttt ggggcctggt tagctggaat cacttttcac
    13741 cacaagactc gaaaatggta ctttaaaaca gtttggtttc ttgggatggt gaccacacta
    13801 gtagccttat attttatttg gaggtaatgg atggtagggt cttcgaggga acacgctgct
    13861 tgggctctag cggactatgg ttttaaggtc gtgattgcag gatctttcgg tgacattcat
    13921 tacaataatg aactcaataa tggcatgttg ccaatcgttc agcctagaga ggttagagag
    13981 aaactagccc agctaaaacc aaccgaccag gtaactgtgg acttggaaca acaaaaaatc
    14041 atctcaccag ttgaagaatt caccttcgag atagatagca agtggaaaca taaactccta
    14101 aatagtttgg atgatatcgg tattaccttg cagtatgaag agttgattgc tgcttatgaa
    14161 aaacaacgac cagcctactg gcaggattag aaaaaataga aaaggaaata tagtaaactg
    14221 aaataagatg taaacaaatg aattggagct taacatccat ttccagcaat tttttagaaa
    14281 ctacagtgga ctattctgga ttcaacacat tataaaatta tgacaaaaca cattcacaag
    14341 aaggctacga cattttaaaa ggtgagggcg gatgtatcgt ttgccctact aaagttggtt
    14401 acattatcat gaccagcaac aaggcaggac ttgagcgtaa gttcgcagcc aaagaacgta
    14461 agcgtaacaa accaggtgtt gttctctgcg gtagcatgga tgaacttcgc gctttagcgc
    14521 aactcaaccc agaaattgaa gcattctact aaaaacattg gatgaagata ttcttcttgg
    14581 ttgtatcctt ccttggaaac cagaagcctt tgaaaaactc aaagcatacg gggatggccg
    14641 tgaagaactt atgactgatg tacgtggtac tagctgtttt gttatcaagt ttggaaaagc
    14701 aggtgaacaa ttggctgcca agctttggga agaaggtaaa atggtctacg cctcatatgc
    14761 ttcaatgaca aaacgattga aactcgctat gagagcaagg tgtaatggtg tctatggtcg
    14821 ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacttca ccagcaccag
    14881 ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca gatactttta
    14941 actcatggga ctactgtcag gttgagtatt attaagataa aaaaagaagt ctagtgttat
    15001 gagatattaa agctcctaac actggacttt ttgtttagaa tttcttttct ttttctatag
    15061 gatatggtat tctatgtaga aaatatatgt taataagtaa tgccaatatt taaacatcat
    15121 tagtaaaagg agttagattg atgaataaaa gaaaagttag tttagaagat ttttataaat
    15181 ggtatagtct aaataaagaa gagttattaa ataaggcaac tgttggtgaa aagtttaatg
    15241 ataaattaaa agaagagttt ctccaggaat ggcctttgga taggatttta acaatgtcaa
    15301 tcgatgaata tgtaatagga aagggacagc aaaataagtc tttatgctac gctcttgaga
    15361 agggaaaata caaaaatcta tttcttggaa tttctggtgg ctcagcttca aaatttggta
    15421 tttattggaa taaaaaaaca aacaaatata aagatcaagc taataatgag atttcagagt
    15481 tggatcagcg attttcaaaa ttaaaatcag atttgtatga aattatcaaa gaaggtattc
    15541 gttttaactt tgaaaatcct atttttgata tgaaaagatc aacaaatgaa tttattggtc
    15601 gttctgctat ggtgacaaaa ttactttgta tctatactga gggagatcct ttctttggtg
    15661 taaatattaa tagtcagaaa gaattttgga accactttgt ttctcagaca aatcaaggtg
    15721 gaccttatct gcaaaatcat aaaataattg aactggtgtc caaaacttat cctgagttgg
    15781 agccatcgaa attaggaact atgctttttg agtattctaa gctttttatg gaaaataagg
    15841 aagacaatag tacaatggat tcatcaaaca attttagtca tcaattaact caatctctat
    15901 taaagtctcc aaaccttatc cttcgtggtg ctcctggcac aggaaagact tatcttgcta
    15961 aagaaattgc caaagaatta acggatggca acgaagacca aatcggattt gtacaatttc
    16021 acccatccta tgattatacg gattttgtag aaggtttaag accagtatca aatggggatg
    16081 gagctattga gtttaggcta caggacggta tttttaaaga tttttgtcag aaagcaaaag
    16141 aaacccaatt gattggagga caagataatt ttgatgaggc ttgggattct tacttagaat
    16201 atataaatgt tgctgaagaa aaagaatata taacaaaaac atcttactta tctgttaata
    16261 gtagacaaaa tttgtcagta aattatgata gtggtgttcc aggatggtca ctacctagca
    16321 aatatgttta cgagttgtat aaagataaaa attataataa gcaagaatac tacaaaagtg
    16381 gtggaaaaac tgtcctagaa acattgagaa agagatttgg tttgaaagac tatgtttccc
    16441 caacagaaat tgatactgat aagaaattcg tcttcatcat cgatgaaatc aatcgtgggg
    16501 agatttctaa gatttttggc gaactctttt tctctatcga ccctggctat cgtggtgaaa
    16561 aaggaagtgt ttctacccaa tatgcaaatc tacacgaaac tgatgaaaag ttctatatcc
    16621 ccgaaaatgt ttacatcatc ggaactatga atgatattga tcgttcagtg gatacctttg
    16681 attttgctat gcgtcgtcgt tttcgttttg ttgaagttac tgccgagggt caagttggca
    16741 tgttggataa agagctgaat atccatgcag aagaagcaaa aattcgtcta agaaacttga
    16801 acgctgctat cgaaaatgtt caggaattaa acagtcatta tcatattgga ccaagttatt
    16861 ttcttaagtt gaaggatgta gattttgact atgaattact ctggtctgat tatattaagc
    16921 ctctcctaga agactacttg cgaggttctt atgatgaggt tgaaactttg gaaactttga
    16981 aaaaagcatt tgaactgaca aataatgagc aaaaagatca ggcagtagct gatgacaatg
    17041 aaggcgatga aaacgatgat gcggattact gataatcaac acaagattat taaagaaaaa
    17101 tttgttgaag aatatcctaa actaagcaat cttcttttag acagaacctt ggaaagtcta
    17161 tcccaagatg aacgtatttt catttttcca aatgatttga ctcatactcc tgatttggat
    17221 aaggaccaaa agatttttga aacagtcaat cagaaaatca agacagggaa cgtgattggt
    17281 tttcttggat atggtcagga aagattaacg atttcctcac gattttctga tgagagtaat
    17341 gaccattttt tgcattatct cttaaacaag gttcttcata tcaatctcac tagtttagat
    17401 gttgctttgt ctcgtgaaga gaggctttat caacttttga tgtatctctt ccccaagtat
    17461 ctacaagctg ctattcgaaa aggtctttat aaggaatacc agagattttc tcataacgac
    17521 agtcatgtta agggagtgat tgatgtaaga aaccatctca agaaaaatct tcctttcacg
    17581 ggaaatattg cctacgcaac gagagagttc acctatgata atcccctcat gcagttggtc
    17641 cgtcacacta ttgaatacat taagaatcag aaaagcattg gtcaaggggt actagataat
    17701 ctctcaacta gtcgtgaaaa cgtatctgaa atcgtgcgtg taacgccctc ttataaacta
    17761 gctgatcgtg ctaagattat tcggggaaat caatctaaac ctatacgtca tgcatacttt
    17821 cacgagtaca gaaacttaca agaactttgt ctgatgatcc taaaccaaga aaagcacggt
    17881 ttagggtatc aagatcaaaa aatctatggt attctctttg atgttgcctg gctttgggaa
    17941 gagtatgttt acaccttgtt gccaaaaggt tttgtacatc ccagaaataa ggataagacg
    18001 gatggaattt cagtattttc tgttgggaaa cgaaaagtat atccagattt ttatgacaga
    18061 gaacgaaaga ttgttctaga tgcaaaatat aaaaaactgg aattgactga aaaaggaatc
    18121 aaccgtgagg acttattcca gctgatttcc tattcttata ttttaaaagc tgagaaggct
    18181 ggactgattt ttcctagtat ggagcagtca gtaaatagtg aaataggaaa agtagctggc
    18241 tatggagctc aattgaagaa gtggtctatt cgaatccctc agaatgcctc attctatagt
    18301 acattttgta aaatgatgga aaattcagaa gaaaatttta aagcgattat tgatgaagaa
    18361 gtggggagaa aataatttcc cctctttctt ttatttttaa cacaagtaaa acccgaacga
    18421 tatattttaa ttcataaaat aatttgacaa aaactgtact ttgatttata ataaattaag
    18481 gaaacgtcgg aaaaggcgta gtgatgcaag agcataggta ggtcattaca aaagaaacga
    18541 gacatcgata tgttaaatga atttccaatt tttgattacg aagatattca attgattcca
    18601 aataaatgtg tcattaaaag ccgtgcagaa gcggatacaa gtgtcacttt aggaaatcac
    18661 acctttaaac tacctgttgt gccagcgaat atgcagacga ttttggatga aaatgtagca
    18721 gagcaactgg ctaaaggtgg ttacttctac attatgcacc gttttgatga ggcaggacgc
    18781 attcctttta ttaaacgaat gcacaatcaa gggctcattg cttctatctc tgtcggtgtt
    18841 aaggattatg agtatgattt tgttagccag ctcaaggctg atactcctga gtatatcact
    18901 attgatattg ctcatggtca tgcggatagc gtgatttcta tgattcaaca catcaagaaa
    18961 gaattgccag atacctttgt cattgctgga aatgtgggaa caccagaagc tgtgcgtgaa
    19021 ttggaaaatg ctggtgcgga tgctactaag gtcggaatcg gtcctggtaa ggtttgtatc
    19081 accaaggtta agactggttt tggtacaggt ggttggcagt tggctgctct acgctggtgt
    19141 gccaaggctg cgcgtaaacc gattatcgct gatggaggaa ttcgtactca cggtgatatt
    19201 gccaagtcta tccgcttcgg tgctagcatg atcatgattg gttccctctt tgcaggacac
    19261 attgaaagtc cagggaaaac gattgaagtc gatggtgaac agttcaaaga atattatggt
    19321 tcagcctcac aatatcaaaa aggtgcttac aaaaatgtgg aaggcaaacg tatcttgctt
    19381 cctgctaaag gtcatctgca agacacttta actgagatgg aacaagacct tcaaagtgct
    19441 atttcttatg caggtggacg tcaggttgct gaccttaaac acgttgatta tgtgatcgtg
    19501 aaaaactcca tctggaatgg ggatgcttcc cactaagacg gggtctttga ccaaaaaact
    19561 tgttattaga gcaaatttct gttataataa aacaagtttc cacccttagt gtaatggata
    19621 tcacgtaaga ttccggttct tgagatgggg gttcgattcc ctcagggtgg atgtaaacat
    19681 cctaaaaagc ctttaatagg gcttttttct ttatcctgac ccaaatttgc cgctaaaact
    19741 gagaatctct gtctaaagaa ttcccaaatg ctttccagtc ccgttttaga gtgactcagg
    19801 gggctttttt tgatataata aaaaggacta ttatcagtta gaaagaggtt ggtatgaaag
    19861 aattacaaac tgtactaaag aatcattttg caatcgaatt tgcagacaaa aatttactgg
    19921 aaactgcctt tactcatacg agttatgcca atgagcaccg cctcttaaaa atttcacaca
    19981 atgaacgctt ggaattttta ggagacgctg ttctacagtt attgatttca gaatatctat
    20041 ataaaaaata tcctaaaaag cctgaaggtg acctatcaaa actccgtgct atgattgtcc
    20101 gtgaggagag tttagctggt tttgcgcgtg attgccagtt tgaccagttt atcaagttgg
    20161 gtaaagggga agaaaaatct ggtggtcgca atcgtgacac cattcttggt gatgcctttg
    20221 aagcctttct tggtgccctt cttttggata aggatgtggc caaggtcaag gaatttatct
    20281 atcaagtcat gattcctaag gttgaagcag gcgaatttga gatgattaca gactataaaa
    20341 cccatctcca agagttactt caggtcaatg gtgatgtggc tattcgttat caggtgattt
    20401 ctgaaacagg gcctgctcac gataaggtct ttgatgtaga agttcttgtt gaaggtaaga
    20461 gcatcggtca aggccaaggt cgttctaaga aattagcaga gcaggaagct gccaaaaatg
    20521 ccgttgagaa ggggctggat tcatgtattt aaaggaaatc gaaattcagg ggttcaagtc
    20581 ttttgctgat aagaccaagg tcgtttttga ccaaggtgtg acggcagttg ttggacccaa
    20641 tggatctgga aagtccaata ttacagaaag tctgcgttgg gctttggggg agtctagtgt
    20701 caagagtctc cgtgggggca agatgccgga tgtcatcttt gctggaaccg aaagtcgcaa
    20761 accgctcaat tatgcttctg tagttgtgac tctggataat catgacggat ttatcaagga
    20821 tgcaggtcaa gaaatcaggg tggaacgcca tatctatcgt agtggagata gcgaatacaa
    20881 gattgacggc aagaaagtcc gtctgcgtga tattcatgac ctcttcttgg atactggatt
    20941 gggacgagat tccttctcta ttatttccca agggaaggtt gaggagattt ttaattccaa
    21001 gcctgaggaa cgacgagcta tttttgaaga agctgcagga gttttaaaat acaagactcg
    21061 cagaaaagaa actgagagta aactgcaaca aactcaggat aatctagacc gcttagagga
    21121 cattatctac gagttggata atcaaatcaa gcctcttgag aagcaagctg agaatgcctg
    21181 taagttttta gacttggaag gacaacgtaa ggctatttat ttagacgttc tggttgctca
    21241 aatcaaggaa aataaggcag aactagagtc gacagaagaa gagctggctc aggttcaaga
    21301 actcttgatg agttattacc aaaagcgtga aaaattagaa gaagaaaatc aaactcttaa
    21361 aaagcaacgc caagatttac aggctgaaat ggccaaagac caaggcagtt tgatggactt
    21421 gactagtctg attagtgatt tagaaagaaa attagcccta tcgaaactgg agtccgagca
    21481 agtggccttg aatcaacagg aggcacaagc tcgtttggct gctttggagg ataagagaaa
    21541 ttcactcagc aaagaaaagt ctgataaaga aagctcttta gctctgttag agggaaatct
    21601 agtccaaaat aatcaaaaac tcaatcgttt agaagctgaa ttgctggctt tctcagacga
    21661 tcctgatcag atgattgagc tcttacgtga acgctttgta gctcttttac aagaagaagc
    21721 ggatgtctca aaccagttga cccgtattga gaatgagttg gaaaatagtc gtcagctttc
    21781 tcaaaaacaa gcagatcaac tagaaaagct gaaagagcaa ttagctatag ctaaagagaa
    21841 ggctagtcag caaaaggaag agcttgaaac tgccaaggag caggttcaga aattattggc
    21901 tgactaccaa gctattgcca aggagcaaga ggagcagaaa acttcctatc aagctcaaca
    21961 aagccaactc tttgaccgtc tggataatct caaaaacaag caggccagag ctcaaagttt
    22021 ggaaaatatc ctgagaaatc atagtaactt ttatgcaggt gttaagagtg ttctccaaga
    22081 aaaagatcgc ctaggtggga ttattggtgc agtcagtgag catctgacct ttgatatgca
    22141 ttatcaaact gccctagaaa ttgcgcttgg agcgagtagt cagcacatta ttgtagaaga
    22201 tgagaatgcg gcaaccaagg ctattgactt ccttaaacgg aacagagccg gtcgtgcaac
    22261 ctttcttcct ttgaccacta ttaaggcgcg tacgatttct agtcagaacc aagatgctat
    22321 cgctgtaagc ccaggtttcc ttgggatggc agatgagttg gtgacttttg atactagact
    22381 ggaagccatt ttcaagaact tgctagctac gacggctatc tttgataccg tagaacatgc
    22441 gcgtgaagct gctcgacaag ttcgttatca ggttcgtatg gtgacattgg atgggacaga
    22501 attacgcacg ggtggttcct atgcgggtgg tgccaatcgc caaaataaca gtattgtcat
    22561 caagccagaa ctggagcaat tacaaaaaga aattgctgca gatgaagcaa gcttgggttc
    22621 agaagaagcg gctttgaaga ccttgcaaga ccagatggct gcattgacag aaagattaga
    22681 agccatcaaa tctcaaggag agcaggcacg tattcaggag caaggcttgt ccctcgctta
    22741 tcagcaaact agtcagcaag ttgaagaact ggaaactctt tggaaactcc aagaagagga
    22801 aatagatcgt ctttctgagg gagattggca agcggataag gaaaaatgtc aagagagcct
    22861 tgctactatc gccagtgaaa agcaaaatct ggaagctgag attgaagaaa ttaagtctaa
    22921 taaaaacgcc atccaagaac gctatcaaaa tttgcaggaa gaggtggcgc aagctcgctt
    22981 gcttaagaca gaactgcaag ggcaaaaacg ttatgaagta gctgatattg agcgtttagg
    23041 caaggaattg gacaatctta atatcgaaca agaagaaatt cagcgcatgc tccaagaaaa
    23101 agttgacaat cttgagaagg ttgatacaga attgctcagt caacaggcgg aagaatccaa
    23161 aactcagaaa acaaatctcc aacaaggttt gattcgcaag cagtttgagt tggatgatat
    23221 agaaggtcaa ctggatgata ttgccagtca cttggatcaa gctcgccagc agaatgagga
    23281 gtggattcgc aagcaaacac gtgctgaagc caagaaagaa aaggtcagcg agcgcttgcg
    23341 ccatctacaa aatcaattaa cagaccagta ccagattagc tatactgaag cactagaaaa
    23401 ggcacatgaa ttggaaaacc tcaatctggc agagcaagag gtgcaggatt tagagaaggc
    23461 tattcgctca ttgggacctg tcaacttgga agctattgac cagtacgaag aagttcacaa
    23521 ccgtctggac tttctaaata gtcagcgaga tgatattttg tcagcgaaaa atctgctcct
    23581 tgaaaccatt acagagatga atgatgaggt caaggaacgc tttaaatcaa cctttgaagc
    23641 tattcgtgag tcctttaaag tgaccttcaa gcagatgttt ggcggaggtc aggcagactt
    23701 gatattgact gagggcgacc ttttaacagc tggtgtggag atttctgttc aacctccagg
    23761 taagaaaatc cagtcgctta acctcatgag tggtggtgaa aaagctctat cggctcttgc
    23821 cttgcttttc tccattattc gtgtcaagac cattcctttt gtcatcttgg atgaggtgga
    23881 agctgcgctg gatgaagcca atgttaaacg ttttggggat tacctcaacc gctttgacaa
    23941 ggacagccag tttatcgttg taacccaccg taagggaacc atggcagcgg ctgattccat
    24001 ctatggagtg accatgcaag aatcgggtgt ttcaaagatt gtttcagtta agttaaaaga
    24061 tttagaaagt attgaaggat gacaattaaa ctagtagcaa cggatatgga cggaaccttc
    24121 ctagatggga atggacgctt tgatatggat cgtctcaagt ctctcttggc ttcctacaag
    24181 gaaaaaggga tttactttgc ggtggcttcg ggtcggggat ttctgtctct ggaaaaatta
    24241 tttgctgatg ttcgtgatga cattattttc atcgcggaaa atggcagttt ggtagagtat
    24301 caaggtcagg acttgtatga agcgactatg tctcgtgact tttatctggc aacttttgaa
    24361 aagctgaaaa cgtcacctta tgtagatatc aataaactgc tcttgacggg taagaagggt
    24421 tcatatgttc tagatacggt tgatgagacc tatttgaaag tgagtcagca ttataatgaa
    24481 aatatccaaa aagtagcgag tttggaagat atcacagatg acattttcaa atttacaacc
    24541 aacttcacag aagaaacgct agaagctggt gaagcttggg ttaatgaaca tgtccctggt
    24601 gttaaggcca tgacaactgg ctttgaatct attgatattg ttctggacta tgtcgataag
    24661 ggtgtagcta ttgttgaatt agctaaaaaa cttggtatca caatggatca ggtcatggct
    24721 tttggagaca atcttaatga cttacatatg atgcaggttg tgggacatcc tgtagctcct
    24781 gaaaatgcac gacctgaaat tttagaatta gcaaagactg tgattggtca ccataaggaa
    24841 cggtcggtta tagcttatat ggagggctta taatggcaga tataaaattg attgcattgg
    24901 acttggacgg gaccttgctg actactgata aaaggctgac ggatcgtacc aaggaaacct
    24961 tgaaagctgc gcgtgatcgt ggtatcaagg tcgtattgac aactggtcgt cccttaaaag
    25021 ccatggactt ctttctccat gagttaggga ctgacggcca tgaagatgag tataccatta
    25081 cttttaatgg tggattagtt cagaaaaata caggagaaat ccttgataaa acagtctttt
    25141 catatgatga tgtggcacgt ttgtatgaag aaacagagaa attatcactg cctcttgatg
    25201 ccatctcaga aggaacagtt tatcaaatcc aatcggacca agaaagtctt tatgccaaat
    25261 tcaatccagc tttgaccttt gttccagtgg actttgaaga cttatctagt caaatgacct
    25321 acaacaaatg cgtgactgcc tttgctcaag aacccttgga tgcagccatt cagaagattt
    25381 ctccagaatt gtttgaccaa tatgaaatct ttaaatcacg tgaaatgttg ctagaatggt
    25441 caccaaagaa tgttcataaa gcaacaggtt tggcaaaact aatcagccat cttggaatcg
    25501 accaaagtca agtgatggct tgtggtgacg aggccaatga cctctctatg attgaatggg
    25561 caggtcttgg tgttgctatg caaaacgctg tttctgaagt aaaggcagcc gcaaatgtag
    25621 tgacgccgat gaccaacgat gaggaagctg tcgcctgggc tatcgaagaa tatgtgctaa
    25681 aggagaacta agatatggga ttgtttgacc gtctattcgg aaaaaaagaa gaacctaaaa
    25741 tcgaagaagt tgtaaaagaa gctctggaaa atcttgattt gtctgaagat gttgatccta
    25801 ccttcacaga agttgaggaa gtttctcagg aagaagcaga ggttgaaatt gttgaacaag
    25861 ctgtgttcca agaagaggaa atccaagaca cagttgaaga aagtctggat ttagagccag
    25921 ttgtagaagt ttctcaaaaa gaagtcgaag aatttccaca ctcagaagaa gggaatactg
    25981 agtttctaga gactatagaa gaaaataatt ctgaagttct tgaagcagaa aggcctcaag
    26041 cagaagaaac cgttcaggaa aaatatgacc gcagtcttaa gaaaactcgt acaggtttcg
    26101 gtgcccgctt gaatgccttc tttgctaact tccgctctgt tgacgaagaa tttttcgagg
    26161 aactggaaga actgctgatt atgagtgatg ttggtgtcca agtcgcttct aacttaacgg
    26221 aggaactacg ttacgaagcc aagcttgaaa atgccaagaa acctgatgca cttcgtcgtg
    26281 tcatcattga gaaattggtt gagctttatg aaaaggatgg tagctacgat gaaagcatcc
    26341 acttccaaga taacttgaca gttatgctct ttgttggtgt gaatggtgtt gggaaaacaa
    26401 cttctatcgg aaaactagcc caccgctaca aacgagctgg taagaaggtc atgctggttg
    26461 cagcagatac cttccgtgcg ggtgcagtag ctcagctagc tgaatggggc cgacgagtag
    26521 atgttccagt agtaactgga cctgaaaaag ctgatccagc cagcgtggtc tttgatggta
    26581 tggaacgtgc cgtggctgaa ggtatcgata ttctcatgat tgatactgct ggtcgtctgc
    26641 aaaataagga taaccttatg gctgagttgg aaaagattgg tcgtattatc aaacgtgttg
    26701 tgccagaagc accacatgaa accttcttgg cacttgatgc atcaacaggt caaaatgccc
    26761 tagtacaggc caaagaattt tcgaaaatca cacctttaac gggaattgtt ttgactaaga
    26821 ttgatggaac tgctcgagga ggtgtggttc tagccattcg tgaagaactc aatattcctg
    26881 taaaattgat tggttttggt gaaaaaatcg atgatattgg agagtttaac tcagaaaact
    26941 ttatgaaagg tctcttggaa ggcttaatct aatcagaagc aaaaatcctg caaggtacaa
    27001 acttgcagga tttttttatt cgaaacgacc atcttgacga taggcgatat ctggttgcca
    27061 agtccatttg gcatcgaatt tttcaagtag gtcaaagctg gcttgaggtc ccatgcttcc
    27121 agctttatag tcatgaagtg gggcaccatt ttcggcccag agctcttcaa tacggtcaat
    27181 caacttccat gacgcaccaa cttcatccca gtggctaaag ttagttgagt tgttatttag
    27241 gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag tcgcatctgt
    27301 acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct tcccatttag
    27361 gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg gagcaagtgg
    27421 ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgggttc ctttttcagt
    27481 cagtcgttta cctgtacgga aaaagaaagg aacaccacgg aatcgatcgc tgtctacaaa
    27541 gaaggcacct gatgtaaagg tttcagttgt tgattctgga ttcacatttg gctcgctacg
    27601 ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac ggataaagtg
    27661 ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa tcttttcagc
    27721 acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg aaagaagttg
    27781 tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt agccaccacg
    27841 ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa aatccttgtt
    27901 ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt ggatcatttc
    27961 cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg ctaggagttc
    28021 gtcattcaac ttgtttgcag ttgcgtaatc tgtaccaaat ggtttttcaa cgatcaagcg
    28081 ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa tggttccaaa
    28141 gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt atttttcatt
    28201 aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga catcatggct
    28261 ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg ccaaatcaag
    28321 gatggactcg acaactacag attcaaaata ttccttactc caaggtctac gggcagttcc
    28381 aataacggca aagtgcttgg aaagattgcc ggatttatat agtctaaaaa gggaagggta
    28441 gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa ccttagatga
    28501 catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag gaaacctcat
    28561 ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat acgaggtaga
    28621 aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta tctaagaact
    28681 ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg tcttcaagga
    28741 actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat cccatctcat
    28801 gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg ttaagtacgt
    28861 ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg atgtctggat
    28921 tcattgctag gccacgagcg atggccacac gttgtttttg accacctgat aggctatctg
    28981 gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt cccaattcct
    29041 cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg ttgtccaata
    29101 cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt tcacggacgt
    29161 ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg tgaccgctag
    29221 tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa cctgaaggac
    29281 cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt aggacttcat
    29341 tttttccata gtgcttgtgt aaatcattta catcaatttt taattttgcc attaacgaat
    29401 cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa gatagaagat
    29461 agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa tcttaccagt
    29521 ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa gagcgataac
    29581 gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga taatcttacg
    29641 catggttttt ccataagaga tacccaagct tcggctggct tccatttggc caactggaac
    29701 ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga gtgagagggc
    29761 aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag actcgatgaa
    29821 gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac cacgaataac
    29881 gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc taaacatacc
    29941 gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag caagagtgat
    30001 accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga gcgttgtttc
    30061 gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt caagaatctt
    30121 ttggaattca ccgtttgcct taaggtttgc aagtccgttg ttgaacattt caatcagttc
    30181 tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc cagagattgg
    30241 agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat catccataac
    30301 ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag caaaggtttt
    30361 gattttgtaa ccgtatttgc tttgattttc tgttaggaag gtttgagaag cagttccgtt
    30421 tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc ttgattcttt
    30481 gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag ttgccttacg
    30541 agcatctgtg acagacatac cagcaatgat accatcggct tgaccagctt ggacagcact
    30601 gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt ctttagcgat
    30661 tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt ggaaaacaaa
    30721 aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa tagcttttaa
    30781 tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc atttcttgat
    30841 aattttatca agactaccat cttttttcat ttcagccaag gcttggttaa attcagtaac
    30901 caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta cagcttcacc
    30961 atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa caggtttgtc
    31021 atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat caccagtgtc
    31081 aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac gttgagcggc
    31141 agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc taattttgtg
    31201 tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca tggtgaagac
    31261 tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt gcccagcttg
    31321 aaccgcattg accgctgcgt caaatccagg ataggacatc tgaatgttcc agcctttaat
    31381 ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat ctgaatcttt
    31441 aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg ctttggcaat
    31501 acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt tcttcatttt
    31561 tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa ggcaaatttt
    31621 tatattttcc gtgtcagaaa atataacatt gatttttcct tttctttctt gaattgctat
    31681 taaaaagtgc tataataata gtatatatag aagaaaagag gacggggata tgaagaataa
    31741 aagaatattt aaagacttcc aagcttcaaa aatgaattta aacatttaca caagcccctt
    31801 gttagccttt gtttttgtct tcataggaga gtttgtggct tatactttat atggtattag
    31861 tttgttagct ctcatcggac ttgctagaaa ttttggagag gctggtcaaa atcttgcaag
    31921 ctacttgcag accttgcatc agagcttgac ggataaaaca agtgactttc gtttaatttt
    31981 aggattactg gcctttggtt ttattcttaa cactgtgttc agatggacaa gaaaagttga
    32041 gaaaagacct attcgaacct tgggatttta tagagagaat ttcctcagca atcttctgaa
    32101 aggatttagt ctaggcctgg cactttttct tctgaccttg ttaggtttag tggtcttagg
    32161 tcaatatcgt ttggaatcca ttcacttgaa tccttattct cttgcctttg tcgtctttac
    32221 tatcccattt tggattttac aggggacagc agaagaagtg gtggcccgtg cttggctact
    32281 tcctcaattg gcctcaagaa ccaatctaaa actagctatt cttatatcta gcctgttctt
    32341 taccctgctt catatgggca attctggcct cacccctcta tctctagtaa atctcttttt
    32401 attcggagtt gccatggctc tttaccttct caaaactgat acagtttggg gtgttgcagg
    32461 tattcatggt gcttggaatt ttgctcaggg taatctcttt gggattttag ttagtggtca
    32521 accgtcagga acgtctctga tgaccttttt accacaaggc aatcaagatt ggctatcagg
    32581 tggttctttt ggcatagaag gttccattat gacaagtctg gtattactac tgctgattgt
    32641 ctatcttgct aataaattaa agaaagaaaa tgaaaggatg tgacttcggt ccgtcctttt
    32701 cttcgtgaaa atactataag tatgctaaaa taggaatagc acatggagag aggattctta
    32761 tgatcaatca cattacagat aatcaattta aactagtatc aaaatatcaa ccatcaggag
    32821 atcaacccca agctatcgag cagttggtgg ataacattga ggggggagaa aaagctcaga
    32881 ttctgatggg ggcgactgga acagggaaga cctatactat gagtcaggtc atttctaaag
    32941 tcaataaacc aactctggtt attgcccaca ataaaactct ggctggtcag ctctatgggg
    33001 agtttaagga atttttccct gaaaatgcag ttgagtattt cgtatcctac tatgattatt
    33061 accagccaga ggcctatgtc ccttctagcg atacctatat tgagaaggat agttctgtca
    33121 atgacgagat tgacaagctt cgccactcag ctacctcagc ccttttggag cgtaatgatg
    33181 ttattgtcgt ggcctcagtc tcttgtatct atggtttggg ttcgcccaag gaatacgctg
    33241 atagtgtcgt tagtctccgt cctggtctag agatttctcg tgataaactc ttgaatgact
    33301 tggtcgatat tcagtttgaa cgcaatgata ttgatttcca acgcggaaga tttcgcgttc
    33361 gtggggatgt ggtagagatt ttcccagctt cccgagatga acatgccttt cgagtagaat
    33421 tttttggaga cgaaattgac cgtattcgtg aagttgaggc tctgacaggt caggtgttgg
    33481 gagaagtgga tcatttagcg attttcccag cgacacactt tgtgaccaat gacgaccaca
    33541 tggaagttgc cattgcaaag attcaggccg agttggaaga acaattagct gtctttgaaa
    33601 aggaaggtaa actgcttgaa gcccagcgtt tgaaacagcg gacagagtat gatatcgaaa
    33661 tgttgcgtga gatgggctat accaatgggg ttgaaaatta ttctcgccac atggatggac
    33721 ggagcgaagg agagcctcct tatacgcttc tcgacttctt cccagatgat ttcttgatta
    33781 tgattgacga gagtcatatg accatagggc aaatcaaggg catgtacaat ggagaccgtt
    33841 cgcgtaaaga aatgctggtt aattatggtt tccgtttgcc gtctgctttg gacaatcgtc
    33901 ctctacgtcg ggaggagttt gagagtcacg ttcatcagat tgtttacgtt tcagcgacac
    33961 ctggtgacta tgaaaatgaa cagaccgaga cagtgattga gcaaatcatt cgtccaacgg
    34021 gactcttgga tccagaggtg gaagtccgtc cgactatggg acagattgat gacctcttgg
    34081 gtgaaatcaa tgcccgcgtt gaaaaaaatg agcgtacctt tatcacaact ttgaccaaga
    34141 aaatggcaga ggacttgacc gactacttca aggaaatggg tatcaaggtc aagtacatgc
    34201 actcggatat caagaccttg gaacggacgg agattatccg tgacctgcgc ttgggtgtct
    34261 ttgatgtctt ggtcggaatt aacctgctcc gtgaaggaat tgacgttcct gaagtgagcc
    34321 tcgtagctat tctcgatgct gacaaggaag gtttccttcg caacgaacgt ggactcatcc
    34381 agactattgg acgtgctgct cgtaacagtg aaggccatgt catcatgtat gcagacacgg
    34441 ttacccagtc tatgcaacgt gctatcgatg aaactgcccg ccgtcggaaa attcagatgg
    34501 cctataatga agagcatggt atcgtaccac agacaatcaa gaaagaaatc cgtgacctga
    34561 ttgccgtgac caaggcagtt gctaaggaag aggacaagga agtcgacatc aatagcctca
    34621 acaaacaaga gcgcaaagaa ctcgtcaaga aactagaaaa acaaatgcaa gaagccgtcg
    34681 aagtgcttga ctttgaactg gcggctcaga tccgtgatat gatgttggaa gtcaaggcct
    34741 tggattaggg gaatagtatg atttatttaa gaaagttaaa gagagaagat ttgatgtctt
    34801 tatgggaaat ggcttattca caacttaatc cagtttggaa acagtatgat gctccctatt
    34861 atgatgatta tcagtatttt tcaaatttta aagaattcga actacaaaaa tcagaatcca
    34921 ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga taaactagtt gggactgttt
    34981 cgcgttattg ggtatgtaaa caaacaagat ggatggaatt gggaattggt atttatgata
    35041 aaaaattctg gaacactggt attgggaaag ttgctatgtt gcagtggata gataggacgt
    35101 ttcaggatta cttggagttg gagcatctgg gtttgacaac ttggtcagga aatcttggta
    35161 tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc tcatattcca aaagttcgtt
    35221 attatcaagg taaatatttt gatagtatta aatatggtat tttgagagaa gactgggaga
    35281 aaatgaatga cggttattat caaatcaatg gaaactcctg aagagataga aggtaaatcc
    35341 cttgttcact ggcaaacgtg gagagaggct tatgatgacc ttttgcctgc agaatttcag
    35401 gagacaatga cattagaaag atgtcgattc tttagtcaaa agtatccaga aaatacattg
    35461 attgcgatag gtgatctgaa ggtagttggt tttatcagtt atggtaactt tcgtgatgag
    35521 actattcaag ctggtgaaat tattgcttta tatgttttaa aagactatta cggaaaaggc
    35581 atagcacaaa agttaatgaa agcagctttg actgctctga atcatttttc tgaaattttc
    35641 ttatgggtat tgaaagataa caagcgagcc attgctttct atcaaaaaat gggttttact
    35701 tttgatggac aagaaaagat acttgaactt ggaaagccta taaaggaaaa acgaatggta
    35761 ttctattcta aaataatttt aaaaagtaga agctaatggc actggtacca agtctgaaaa
    35821 tttaataaat tagaaagcga gtaaatttat gtcccgttcc caattaacga ttttaacaaa
    35881 tatttgtctg attgaagacc ttgaaactca gtgcgtggtt atgcagtacc gtgctcctga
    35941 aaccaatcgc tggtctggtt atgcctttcc tggaggtcat gtagaaaatg gtgaggcttt
    36001 tgcggagtct gtcattcgtg aaatctacga agaaacagga ttgactatcc aaaatccgca
    36061 actggtaggt gttaaaaatt ggcctttgga tacagggggg cgctacattg tcttttgtta
    36121 caaggcgacc gagtttactg gaactcttca atcttcagac gagggagaag tttcttgggt
    36181 gcaaaaagac cagattccaa acttgaatct ggcctatgat atgctaccat tgatggaaat
    36241 gatggaagct cccgacaagt cagagttttt ctaccctcgc cgtacagaag acgattggga
    36301 aaagaaaatc ttctagtctt ttactaaata acctagctga tccaaggctt cctcgatata
    36361 gtggaggtct tgttgtgttt cggcttcgac taggtggtaa tggatgccat ctgtcaattc
    36421 agatagaggt ctaaagtcag aatgctcgac ttgttctaga aaatgttgca catctctgcg
    36481 acaagacagt ttaagcaagg tttcaatttc tccataaacg ggatggtcaa tcaaggtatt
    36541 ctggacatgc ccaccattat cgacaatagc aaggagttcc tgaccgattt cttcaacttg
    36601 atgtttcact ttgaaaagtt tgtgaacata aggattggta tcaatttgct tatagatgta
    36661 gccacgattg gtggatagga taggagcgcc atcggctctc aaaattgcaa tgtcctgcac
    36721 aatgacctga cgtgtgacat gaaaatgttc cgccaaactt tggccattaa gggctttagg
    36781 agcttctttc aagagttgga gcagggcttg tttgcgatct tttgtcatag cttttccttt
    36841 taacggcgtt ttcgaagcac tttatagaca gctagtgcta atgtatagtc taccatacta
    36901 tggataattg tgccaaatcc aactagtaca aatagaacat agaacatgtt ttctacattg
    36961 gtacccgaag ttgcgtaaaa aaggacacag gctaatactt cagcaagggc atgaacaaca
    37021 gccaaaacaa aattgaaaac ccaggaagat tttggtttat ctagggtatc ggggaatttt
    37081 tgtaggtaaa gagctcctaa agcaccaaaa gatatatggg aaaaagcccg aaaaacgata
    37141 accatgggat agccagccat caaaaatcca aaactagagg ctaggatgac aaaaactgcc
    37201 atcaagggcg acaagaacat ggctataaaa atagcgatgt ggctccccaa agtataggaa
    37261 gcaggtggaa tgacaatctt gaaaggcata acaattggaa tcaaaatcgc aatagccgtt
    37321 aaaagggctg tcattgtcat aaattgtgtc tttttccgtg tattcacaag aatctccttt
    37381 ttaactgcat atacactagt atggtacaat aaaccagaca ataaagcaag aatttacttg
    37441 ggtttataga tcatttttta gttaaaag
//
LOCUS       DAVLZG010000014        35063 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLZG010000014 DAVLZG010000000
VERSION     DAVLZG010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.014"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            143..2125
                     /locus_tag="VYO72_000672"
     CDS             143..2125
                     /locus_tag="VYO72_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707085.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2426..7729
                     /locus_tag="VYO72_000673"
     CDS             2426..7729
                     /locus_tag="VYO72_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1707086.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7896..10055)
                     /locus_tag="VYO72_000674"
     CDS             complement(7896..10055)
                     /locus_tag="VYO72_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1707087.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10052..10648)
                     /gene="recU"
                     /locus_tag="VYO72_000675"
     CDS             complement(10052..10648)
                     /gene="recU"
                     /locus_tag="VYO72_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1707088.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10714..11241
                     /locus_tag="VYO72_000676"
     CDS             10714..11241
                     /locus_tag="VYO72_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1707089.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11311..11640
                     /gene="gpsB"
                     /locus_tag="VYO72_000677"
     CDS             11311..11640
                     /gene="gpsB"
                     /locus_tag="VYO72_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1707090.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11661..12041
                     /gene="rnpB"
                     /locus_tag="VYO72_000678"
     ncRNA           11661..12041
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYO72_000678"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12126..13283
                     /locus_tag="VYO72_000679"
     CDS             12126..13283
                     /locus_tag="VYO72_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1707091.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13296..14690
                     /gene="mapZ"
                     /locus_tag="VYO72_000680"
     CDS             13296..14690
                     /gene="mapZ"
                     /locus_tag="VYO72_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1707092.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14766..16190
                     /gene="gndA"
                     /locus_tag="VYO72_000681"
     CDS             14766..16190
                     /gene="gndA"
                     /locus_tag="VYO72_000681"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1707093.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSHKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16202..16891
                     /locus_tag="VYO72_000682"
     CDS             16202..16891
                     /locus_tag="VYO72_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707094.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVAYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESVTETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            16989..18005
                     /gene="cbpC"
                     /locus_tag="VYO72_000683"
     CDS             16989..18005
                     /gene="cbpC"
                     /locus_tag="VYO72_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1707095.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEPKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYFGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            18127..19005
                     /gene="mvk"
                     /locus_tag="VYO72_000684"
     CDS             18127..19005
                     /gene="mvk"
                     /locus_tag="VYO72_000684"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1707096.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            18987..19940
                     /gene="mvaD"
                     /locus_tag="VYO72_000685"
     CDS             18987..19940
                     /gene="mvaD"
                     /locus_tag="VYO72_000685"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1707097.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            19927..20934
                     /locus_tag="VYO72_000686"
     CDS             19927..20934
                     /locus_tag="VYO72_000686"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1707098.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            20918..21928
                     /locus_tag="VYO72_000687"
     CDS             20918..21928
                     /locus_tag="VYO72_000687"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1707099.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDNS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            22005..22703
                     /locus_tag="VYO72_000688"
     CDS             22005..22703
                     /locus_tag="VYO72_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1707100.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            22700..23695
                     /locus_tag="VYO72_000689"
     CDS             22700..23695
                     /locus_tag="VYO72_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1707101.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            23709..24341
                     /locus_tag="VYO72_000690"
     CDS             23709..24341
                     /locus_tag="VYO72_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707102.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            24342..24583
                     /locus_tag="VYO72_000691"
                     /pseudo
     CDS             24342..24583
                     /locus_tag="VYO72_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            24565..24819
                     /locus_tag="VYO72_000692"
     CDS             24565..24819
                     /locus_tag="VYO72_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1707103.1"
                     /translation="MAANYLKAMQSYLKETDLPKLEQLVVTKSWWDTVDILDRVVGSL
                     VYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLAS"
     gene            24844..25110
                     /locus_tag="VYO72_000693"
                     /pseudo
     CDS             24844..25110
                     /locus_tag="VYO72_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25260..25499
                     /locus_tag="VYO72_000694"
     CDS             25260..25499
                     /locus_tag="VYO72_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707104.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            25580..26401
                     /gene="cbpG"
                     /locus_tag="VYO72_000695"
     CDS             25580..26401
                     /gene="cbpG"
                     /locus_tag="VYO72_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1707105.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            26420..27442
                     /gene="cbpF"
                     /locus_tag="VYO72_000696"
     CDS             26420..27442
                     /gene="cbpF"
                     /locus_tag="VYO72_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1707106.1"
                     /translation="MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAINTTVGGYYLNY
                     NGEWVK"
     gene            complement(27570..28918)
                     /locus_tag="VYO72_000697"
                     /pseudo
     CDS             complement(27570..28918)
                     /locus_tag="VYO72_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            29127..30896
                     /locus_tag="VYO72_000698"
     CDS             29127..30896
                     /locus_tag="VYO72_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1707107.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     VAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            30920..32875
                     /locus_tag="VYO72_000699"
     CDS             30920..32875
                     /locus_tag="VYO72_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1707108.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            32877..33314
                     /locus_tag="VYO72_000700"
     CDS             32877..33314
                     /locus_tag="VYO72_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1707109.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            33376..34512
                     /locus_tag="VYO72_000701"
     CDS             33376..34512
                     /locus_tag="VYO72_000701"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1707110.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT        10674 a         6239 c         7838 g        10312 t
ORIGIN      
        1 tatagttgag ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat
       61 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
      121 gaaagtttta aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac
      181 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
      241 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc
      301 taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg
      361 ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac
      421 ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc
      481 ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata aaaaatcaga
      541 tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat
      601 caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt
      661 gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa
      721 tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc caagtagtct
      781 cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg ttgaatttgc
      841 gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta aattgtcatt
      901 ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc
      961 agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta tgaaggacaa
     1021 tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca
     1081 gtcctataaa tatacatcta agaccagtga agaacaaaaa acatctacga aaaaggctct
     1141 cttaaacaag gatttccgtc aggctattgc atttggattt gaccgtacag cctatgcctc
     1201 tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg ttccaccaac
     1261 atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta
     1321 tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga
     1381 aaaagccaag gctgaatttg ctaaagctaa atcagcttta caagcagaag gtgtgacttt
     1441 cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc agcgcgtcca
     1501 atctatgaaa caatccttgg aagcaacttt aggagcggat aatgtagtca ttgatattca
     1561 acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggtga
     1621 agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta
     1681 ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag ggtttgactc
     1741 aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac
     1801 tgaggctggt gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca
     1861 agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat
     1921 cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata aaggcacaag
     1981 tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata
     2041 ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga
     2101 agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc
     2161 cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta ctgaccccca
     2221 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     2281 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     2341 ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta aacgcttgct
     2401 aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     2461 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     2521 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccagctga
     2581 tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg aagcgcctaa
     2641 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
     2701 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
     2761 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
     2821 acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
     2881 aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg gcttgaccgt
     2941 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg aaaagggcaa
     3001 atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt ttgtcggtta
     3061 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
     3121 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
     3181 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
     3241 agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg cgggctctta
     3301 tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg taaaagcgga
     3361 tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
     3421 tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc gtgtcaagga
     3481 atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
     3541 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
     3601 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgcct
     3661 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
     3721 cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta gtttcctcgg
     3781 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
     3841 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
     3901 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
     3961 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
     4021 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
     4081 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
     4141 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
     4201 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
     4261 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
     4321 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
     4381 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
     4441 tggtgtcgaa gacttcaaga ccctgattga gaaggctaag aaatatggag ctcatctagg
     4501 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
     4561 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
     4621 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
     4681 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
     4741 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
     4801 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
     4861 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
     4921 ccgtaaccac caaaaagatg cttgggtagg ggactacaga agttatggtg gtgcagccaa
     4981 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
     5041 ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt acttccaaca
     5101 cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
     5161 ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata ataaagtagt
     5221 tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta cagtaacgct
     5281 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
     5341 tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc aggccggtac
     5401 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
     5461 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttaccctaga
     5521 tcttctagca aatcaaccat acgtacttta ccgttcaaaa caaaccaatc ctgaaatgtc
     5581 atggagtgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
     5641 gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
     5701 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
     5761 accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
     5821 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
     5881 caactatgta aaagcctacg cccacaatac acgtcgtaac aatgctacag ttgacgatac
     5941 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct caaatgttac
     6001 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
     6061 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
     6121 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg ttgaaggtgt
     6181 tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac gtggttggaa
     6241 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
     6301 gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg aagcaggtaa
     6361 gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg cttttgtagt
     6421 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
     6481 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggtaacct tccttgtgac
     6541 aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg caagtaatac
     6601 tcgtagtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
     6661 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
     6721 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
     6781 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
     6841 gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
     6901 agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
     6961 tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg taggcaagcc
     7021 tgcaaccatg gtcttgaaag aagcaactga aatcactgga cttcgttatg ttccacgtgg
     7081 atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa
     7141 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
     7201 tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt acggagatgg
     7261 tggcgataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
     7321 acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat taacagacaa
     7381 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
     7441 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
     7501 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gctctttagt
     7561 ttccaatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag aaacacctga
     7621 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc tagcaagtgt
     7681 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
     7741 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
     7801 aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca atagtgctat
     7861 gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
     7921 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
     7981 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
     8041 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga
     8101 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
     8161 tctggattgc ttccttcaga cagataggtc atcatagagc ggtaaacttt ggcagcgacc
     8221 gtaagaccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt
     8281 gaatatttac gcgtatagcc agcaaatagt tcatcaggtg ctacaaattg agaggtcttg
     8341 atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg
     8401 agccaagcaa gataggcatt tcgtccagtt ccataactca agactgtttt catcatgtcg
     8461 gtcatcatat aggctgtcgt ttccttcatg gcacgagttc cgacattaga gaactctttt
     8521 tcactcccat cactaaagac gactttatgg atatacattg gtttatagta agttccacca
     8581 tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct
     8641 gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattccg
     8701 agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct
     8761 gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta
     8821 tcccagttat aaacaggggt atttgtccca gggtagttat agggctcatc gtgaacgata
     8881 gtagcagttg aatcgtagat accgtactcc aaggcaggag catagtctgt gatcggtttc
     8941 atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta
     9001 cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg
     9061 gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata
     9121 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
     9181 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
     9241 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
     9301 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
     9361 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
     9421 gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
     9481 ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta
     9541 tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac
     9601 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
     9661 aacttaatca actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg
     9721 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
     9781 tcttcgatag aaacgattgc tttaaccaaa tctgtgggaa tatcattagc ttgggcattg
     9841 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
     9901 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
     9961 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
    10021 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
    10081 ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat
    10141 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
    10201 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    10261 agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
    10321 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
    10381 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    10441 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
    10501 gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    10561 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatgtttgt cttttttgtg
    10621 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
    10681 attataccat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
    10741 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
    10801 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
    10861 gggactttgg gctttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
    10921 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
    10981 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ctatcctcgc
    11041 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
    11101 tcctatcttt tttatgatga agaaaatgaa acaaaactag cttattttta ccaaaagatg
    11161 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
    11221 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
    11281 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
    11341 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
    11401 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
    11461 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
    11521 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
    11581 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
    11641 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
    11701 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
    11761 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
    11821 taggcttgaa agtgccacag tgacgaagtc tttctggaaa cagagagagt ggaacgcggt
    11881 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
    11941 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
    12001 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
    12061 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
    12121 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
    12181 ttggtcgtga agtgcgagag ttgggctacg attgtcagat tgaaaatgga cgtgttcgtt
    12241 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gctgcgggca gcagatcgta
    12301 tcaaaattat cgtaggaacg ttccctgcta agacttttga agagctattt cagggagttt
    12361 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    12421 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    12481 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    12541 gcccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    12601 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    12661 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    12721 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    12781 tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    12841 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    12901 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    12961 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta tgttccgata
    13021 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    13081 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    13141 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    13201 agcgtaagtt atacaacgga accttgaaag tggatctgta tcaatatttt ggtcagcgtg
    13261 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    13321 aaaaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    13381 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    13441 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    13501 aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc
    13561 gtgaggctgt agagaagtca gaagcttctt cggaggaagt tccatcttct gaagacatct
    13621 tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg
    13681 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    13741 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    13801 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    13861 aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac
    13921 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    13981 aactgaatca actcaagact ttacttgata agctggaagg tagtcgtgaa catacgcttg
    14041 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc
    14101 aatttgagaa accagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg
    14161 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    14221 ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaaacta
    14281 gcagctcaag ttcaagtcaa gcaagttcaa atacgactag tgagccaaaa ccaagtagtt
    14341 caaatgagac tagaagtagt cgcagtgaag tcaatatggg tctctcgagt gcaggggttg
    14401 ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc tgctattgat gatagtaata
    14461 actctgcctg ggattttgcg gatggtgtct tggaacaaat tctagcgact tcacgttcac
    14521 gtggctatat cactggagac caatatatcc ttgaacgtgt caatatcgtt aacggcaatg
    14581 gttattacaa cctctataag ccagatggaa cctatctctt tacccttaac tgtaagacag
    14641 gctactttgt cggaaatggc gctggtcatg cggatgactt ggactactaa gcagtcgtta
    14701 caaaattctt tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa caagaggagt
    14761 gtcaaatgac aaaagctaac tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg
    14821 cccttaatat tgaatcacgt ggttacacag ttgctatcta caaccgtagt aaagaaaaaa
    14881 cggaagatgt gattgcttgc catcctgaaa agaattttgt accaagctat gacgttgaaa
    14941 gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa gctggacctg
    15001 gtacagatgc tactatccaa gcccttcttc cacaccttga caagggtgat atcttgattg
    15061 acggaggaaa cactttctac aaagatacca tccgtcgtaa tgaagaattg gcaaactcag
    15121 gtatcaactt tatcggtact ggagtttctg gtggtgaaaa aggtgccctt gaaggtcctt
    15181 ctatcatgcc tggtggacaa aaagaggcct acgaattggt tgcggatgtt cttgaagaaa
    15241 tctcagctaa agcaccagaa gatggcaaac catgtgtgac ttacatcggc cctgatggag
    15301 ctggtcacta tgtgaaaatg gttcacaatg gtattgagta cggtgatatg caattgatcg
    15361 cagaaagcta tgacttgatg caacacttgc taggcctttc tgcagaggat atggctgaaa
    15421 tctttactga gtggaacaag ggtgaattag acagctattt gatcgaaatc acagctgata
    15481 tcttgagcca taaagacgat gaaggccaag atggaccaat cgtagactac atccttgatg
    15541 ctgcaggtaa caagggaact ggtaaatgga ctagccaatc atctcttgac cttggtgtac
    15601 cattgtcact gattactgag tcagtgtttg cacgctacat ttcaacttac aaagaagaac
    15661 gtgtatatgc tagcaaggtg cttccaaaac cagctgcctt caactttgaa ggagacaagg
    15721 ctgaattgat tgaaaagatc cgtcaagccc tttacttctc aaaaatcatt tcatacgcac
    15781 aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg ccatttgcag
    15841 atatcgcatc tatctggcgt gatggctgta tcatccgttc tcgtttcttg caaaagatta
    15901 cagatgctta caaccgcgat gcagatcttg ccaaccttct tttggacgag tacttcttgg
    15961 atgttactgc taagtatcaa caagcagtgc gtgatatcgt agctcttgcg gttcaagctg
    16021 gtgtgccagt gccaactttc tcagcagcta ttacttactt tgatagctac cgttcagctg
    16081 accttccagc taacttgatc caagcacaac gtgactactt tggtgctcac acttaccaac
    16141 gtaaagacaa agaaggaacc ttccactact cttggtatga cgaaaaataa gtaggtcagc
    16201 catggggaaa cggattttat tacttgagaa agaacgaaat ctagctcatt ttttaagttt
    16261 ggaactccag aaagagcagt atcgggttga tctggtagag gaggggcaaa aagccctctc
    16321 catggctctt cagacagact atgatttgat gttattgaac gttaatctgg gagatatgat
    16381 ggctcaggat tttgcagaaa aattgagtcg aactaaacct gcctcagtca tcatgatttt
    16441 agatcattgg gaagacttgc aagaagagct ggaagttgtt cagcgttttg cagttgcata
    16501 catttataag ccagtcctta tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg
    16561 tcgggacttc attgatcaac actgcagtct gatgaaagtt ccaaggactt accgcaatct
    16621 taggatagat gttgaacatc acacggttta tcgtggtgaa gagatgattg ctctgacccg
    16681 ccgtgagtat gaccttttgg cgacacttat gggaagcaag aaagtattga ctcgtgagca
    16741 attgttggaa agtgtttgga agtatgaaag tgtgaccgag acaaatatcg tagatgtcta
    16801 tatccgctat ctacggagca agcttgatgt taaaggccaa aaaagctaca ttaaaaccgt
    16861 gcgtggtgtt ggatatacca tgcaagaata gataagcagt tgcagttgtg taactgcttt
    16921 tttgaggagt ttttatatat tgacatgcag tcgggtcttt gctacaatcg ttttaggagg
    16981 atatatagat gaaacttttg aaaaaaatga tgcaagttct actagcagtc tttttctttg
    17041 gtttgctagc tacaaatacg gtatttgcga ataccacagg tggccaattt gttgataagg
    17101 ataatagaaa atattatgta aaagatgatc ataaagcaat ctattggcat aaaatagacg
    17161 gtaaaactta ctattttggt gatattggag agatggttgt cggttggcaa tacttagaaa
    17221 ttcctggaac aggttatcgt gataatttat tcgataacca accagttaat gagattggcc
    17281 ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa acagataaac
    17341 aagtactaga gccaaaaacg tctgaaaata caggaaaagt atacggtgaa caatatcctc
    17401 tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag acaggctgga
    17461 tttatgaaga cggcaattgg tattatttaa ataagctagg aaattttggc gatgattctt
    17521 acaatccact accaattggt gaagttgcta agggttggac tcaagatttt catgttacta
    17581 ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca ggtaagatgc
    17641 ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct ggttctatgg
    17701 caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa aatggtgata
    17761 tgaaaacagg atggcaatac tttggtaaca agtggtacta cctccgttca tcaggagcta
    17821 tggtaactgg ctggtatcaa gatggtttaa cttggtacta cctaaatgca ggtaatggag
    17881 acatgacgac aggttggttc caggtcaatg gcagatggta ctacgcttat agctcaggtg
    17941 ccttggcagt gaatacgacc gtagatggct attctgtcaa ctataatggc gaatgggttc
    18001 aataatgaaa gaagcgattg tgaatggaaa caatcgcttt ttttgtgaaa atataataaa
    18061 atagatagga aagaattaat acttgtatga aaaataagac gttttttcgt ctagtaaaag
    18121 gaaaaaatga caaaaaaagt tggtgtcggt caggcacata gtaagataat tttaataggg
    18181 gaacatgcgg tcgtttacgg ttatcctgcc atttccctgc ctcttttgga ggtggaggtg
    18241 acctgtaagg tagttcctgc agagagtcct tggcgccttt atgaggagga taccttgtcc
    18301 atggcggttt atgcctcact ggagtatttg aatatcacag aagcctgcat tcgttgtgag
    18361 attgactcgg ctatccctga gaaacggggg atgggttcgt cagcggctat cagcatagcg
    18421 gccattcgtg cagtatttga ctactatcag gctgatctgc ctcatgatgt actagaaatc
    18481 ttggtcaatc gagctgaaat gattgcccat atgaatccta gtggtttgga tgctaagacc
    18541 tgtcttagtg accaacctat tcgctttatc aagaacgtag gatttacaga acttgagatg
    18601 gatttatccg cctatttggt gattgccgat acgggtgttt atggtcatac tcgtgaagcc
    18661 atccaagtgg ttcaaaataa gggcaaggat gccctaccgt ttttgcatgc cttgggagaa
    18721 ttaacccagc aagcagaagt tgcgatttca caaaaagatg ctgaaggact gggacaaatc
    18781 ctcagtcaag cgcatttaca tttaaaagaa attggagtca gtagccctga ggcagacttt
    18841 tgggttgaaa cgactcttag ccatggtgct ctgggtgcca agatgagcgg tggtgggcta
    18901 ggaggttgta tcatagcctt ggtaaccaat ttgacacacg cacaagaact agcagaaaga
    18961 ttagaagaga aaggagctgt tcagacatgg atagagagcc tgtaacagta cgttcctacg
    19021 caaatattgc tattatcaaa tattggggaa agaaaaaaga aaaagagatg gtgcctgcta
    19081 ctagcagtat ttctctaact ttggaaaata tgtatacaga gacgaccttg tcgcctttac
    19141 cagccaatgt aacagctgac gaattttaca tcaatggtca gctacaaaat gaggtcgagc
    19201 atgccaagat gagtaagatt attgaccgtt atcgtccagc tggtgagggc tttgtccgta
    19261 tcgatactca aaacaatatg cctacggcag cgggtctgtc ctcaagttct agtggtttgt
    19321 ccgccctggt caaggcttgt aatgcttatt tcaagcttgg attggataga agtcagttgg
    19381 cacaggaagc caaatttgcc tcaggttctt cttctcggag tttttatgga ccactaggag
    19441 cctgggataa ggatagtgga gaaatttacc ctgtagagac agacttgaaa ctagctatga
    19501 ttatgttggt gctagaggac aagaaaaaac caatctctag ccgtgacggg atgaaacttt
    19561 gtgtggaaac ctcgacgact tttgacgact gggttcgtca gtctgagaag gactatcagg
    19621 atatgctgat ttatctcaag gaaaatgatt ttgccaagat tggagaatta acggagaaaa
    19681 atgccctggc tatgcatgct acgacaaaga ctgctagtcc agccttttct tatctgacgg
    19741 atgcctctta tgaggctatg gactttgttc gccagcttcg tgagaaagga gaggcctgct
    19801 actttaccat ggatgctggt cccaatgtta aggtcttctg tcaggagaaa gacttggagc
    19861 atttatcaga aattttcggt catcgttatc gcttgattgt gtcaaaaaca aaggatttga
    19921 gtcaagatga ttgctgttaa aacttgcgga aaactctatt gggcaggtga atatgctatt
    19981 ttagagccag ggcagttagc tttgataaag gatattccca tctatatgag ggctgagatt
    20041 gctttttctg acagctaccg tatctattca gatatgtttg atttcgcagt ggacttaagg
    20101 cctaatcctg actacagctt gattcaagaa acgattgctt tgatgggaga cttcctcgct
    20161 gttcgcggtc agaatttaag acctttttcc ctaaaaatct gtggcaaaat ggaacgagaa
    20221 gggaaaaagt ttggtctagg ttctagtggc agcgtcgttg tcttggttgt caaggcttta
    20281 ttggctctct ataatctttc ggttgatcag gagctcttgt tcaagctgac tagcgctgtc
    20341 ttgcttaagc gaggagacaa tggttccatg ggcgaccttg cctgtattgt ggcagaggat
    20401 ttggttctct accagtcatt tgatcgccag aaggcggctg cttggttaga agaagaaaac
    20461 ttggcgacag ttctggagcg tgattgggga ttttttatct cacaagtgaa accaacttta
    20521 gaatgtgatt tcttagtggg atggaccaag gaagtggctg tatcgagtca catggtccag
    20581 caaatcaagc aaaatatcaa tcaaaatttt ttaagttcct caaaagaaac ggtggtttct
    20641 ttggtcgaag ccttggagca ggggaaagcc gaaaaagtta tcgagcaagt agaagtagcc
    20701 agcaagcttt tagaaggctt gagtacagat atttacacgc ctttgcttag acagttgaaa
    20761 gaagccagtc aagatttgca ggccgttgcc aagagtagtg gtgctggtgg tggtgactgt
    20821 ggcatcgccc tgagttttga tgcgcaatca accaaaacct taaaaaatcg ttgggccgat
    20881 ctggggattg agctcttata tcaagaaagg ataggacatg acgacaaatc gtaaggacga
    20941 gcatatcctc tatgcccttg agcagaaaag ttcctataat agctttgatg aggtggagct
    21001 gattcattct tccttgcctc tttacaatct ggatgaaatc gatctttcga cagagtttgc
    21061 tggtcgaaag tgggactttc ctttttatat caatgccatg actggtggaa gtaataaggg
    21121 aagagaaatc aatcaaaagc tggctcaggt ggcggaatcc tgtggtattt tatttgtaac
    21181 gggttcttat agcgcagccc tcaaaaatcc aacggataat tctttttctg tcaagtctag
    21241 tcatcccaat ctcctccttg gaaccaatat tggattggac aaacctgtcg agttaggact
    21301 tcagactgta gaagagatga atcctgttct attgcaagtg catgtcaatg tcatgcagga
    21361 attactcatg cccgagggag aaaggaagtt tagaagctgg caatcgcatc tagcagatta
    21421 tagcaagcaa attcccgttc ctattgtcct caaggaagtg ggctttggaa tggatgccaa
    21481 gacaatcgaa agagcctatg aattcggtgt tcgtacagtg gacctatcgg gtcgtggtgg
    21541 caccagcttt gcctatatcg aaaaccgtcg tagtggccag cgtgattacc tcaatcaatg
    21601 gggtcagtct accatgcagg cccttctcaa tgcccaagaa tggaaagata aggtcgaact
    21661 cttggttagt ggaggggttc ggaatccgct ggatatgatt aagtgcttgg tttttggtgc
    21721 taagtctgtg ggattgtcac gaaccgttct ggaattggtt gaaacctaca cagttgaaga
    21781 agtgattggc attgtccaag gctggaaagc agacctacgc ttgattatgt gttcccttaa
    21841 ctgtgccacc atagcagatc tacaaaaagt agactatctt ctttatggaa aattaaaaga
    21901 agcaaatgat cagatgaaaa aggcgtaacc agcgcctttt ttccatcctc agactgaggt
    21961 gacttttttg aattgtgata aaatagaagg gagaggatga acctatgaga aaatttaaaa
    22021 tctttttatt tatcgaagcc tgtcttctga caggagctct gattttgatg gtatcagagc
    22081 atttttcgcg ttttctgctg atactattcc tctttttgct tttgattcgc tactacactg
    22141 gtaaagaggg gaataatctt cttttagtag cggcaaccat tctcttcttt ttcattgtta
    22201 tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt tatctatagt ctctttcttc
    22261 tttacccgat gatgaaccag gaaaaagagc agaccaattt ggtttttgaa gaggttgtga
    22321 cggttaagaa ggagaaaaat cgttggtttg gaaatcttca tcatttttca agctaccaga
    22381 cttgccaatt tgatgatatc aatctctttc gcttcatggg caaggacact attcatctgg
    22441 agagagtcat cttaaccaat catgacaatg tcattatcct cagaaagatg gtaggaacga
    22501 ccaaaatcat cgtacctgta gatgtggaag tcagtctcag cgttaactgt ctctatgggg
    22561 atttgacttt tttcaaccag cccaagcgag ccctccgcaa tgaacactat catcaagaaa
    22621 caaaagacta tctcaagagt aacaagagtg tcaagatttt cttgaccact atgattggtg
    22681 atgttgaggt ggttagagga tgaaaaaaca agcctatgtc attatcgctc tcacctcctt
    22741 cctgtttgtc ttttttttct cccatagctt gctggaaata cttgattttg actggtctat
    22801 ctttttgcac gatgtcgaaa aaacagaaaa atttttcttt ttattgttgg ttttcagcat
    22861 gtccatgacc tgtctcttag ccctgttttg gcgagggatc gaagagcttt ctctaagaaa
    22921 aatgcaggct aatctcaagc gtttattggc agggcaagaa gtggttcagg ttgtagatcc
    22981 agatttggat gccagtttca agtccttatc aggtaaactt aaccttttga cagaggctct
    23041 tcaaaaagct gaaaatcata gccttgctca ggaagaggaa atcatcgaga aggaacggaa
    23101 gcgaattgct cgggatttgc acgatacagt cagtcaggag ttgtttgcgg cccacatgat
    23161 tttatcgggt atcagtcagc aggctttgaa attggataga gaaaagatgc agacccagtt
    23221 gcagagtgtc acagctattt tagaaacagc ccagaaggat ttgcgggttt tgctcttgca
    23281 tttgcgacca gttgaactgg agcagaagag cttgatagaa gggattcaaa ttcttttaaa
    23341 agagcttgag gacaagagtg atcttagggt tagtctcaag cagaatatga cgaaattgcc
    23401 taagaaaatc gaggagcata tcttccgtat cctgcaagag ttgattagca ataccctccg
    23461 ccatgcccag gcatcttgcc tagatgtcta cctctatcag acagatgttg aattgcaact
    23521 gaaggtggtg gacaatggga ttggtttcca gttagggagc ttagacgact tgagttatgg
    23581 actgcgaaat atcaaggagc gggttgaaga tatggctgga acagttcaac tcttgacagc
    23641 tcccaagcaa gggctggcgg ttgatatccg tattcctctg ttagataagg aatgataaag
    23701 gagtaaagat gaaaatttta ctagtagatg accatgaaat ggtccgattg ggcttgaaaa
    23761 gctactttga cctccaagac gatgtagaag ttgtgggtga ggcgtccaac gggtctcaag
    23821 ggattgactt ggccttggaa ctgcgtccag atgtcattgt catggatatt gtcatgcctg
    23881 agatgaatgg gattgacgcg accttagcaa tccttaaaga atggcctgaa gccaagattt
    23941 tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc agtcttagat gctggtgcca
    24001 aaggctatat gctcaagact tctagtgcag atgaattgct tcatgccgtc agtaaggtag
    24061 ctgctggcga gctggccatt gagcaagagg ttagcaagaa ggttgaatac caccgcaatc
    24121 atatggaact tcatgaagaa ttgactgcgc gtgagcgaga tgttctccaa ctcatcgcca
    24181 agggctacga aaatcagcgc atcgcagatg acctctttat ctctctcaag acggtcaaga
    24241 cccacgtgtc caatattctt gccaaacttg aagtcagcga tcgtacccag gcggctgtct
    24301 atgcctttca gcaccatttg gtggggcaag aggagtttta gatgagttta gcagatttac
    24361 ttgaggagct agaagcagca aaagactcta aaaaagcaag gtccatggaa gcctatatgc
    24421 gccatcaatt ttcttttcta ggtattgcgg tgcctgaaag aaataaactc tataaaatat
    24481 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    24541 aagaatccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    24601 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    24661 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacactc tgaactagaa
    24721 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    24781 caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgctctttg attttcattg
    24841 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    24901 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    24961 aaccaaacag aattttttat caataaagcc attggctgga ctctgcgaga ctactccaaa
    25021 acgaatccca cttgggtaac atgctttatt gagaaaaaca aggaaagaat ggctgaactt
    25081 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    25141 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    25201 ctatagtaga ttaagaaatt tagaatagta cgctataatt acattaggag gatacaataa
    25261 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    25321 gccagttatc gacagtatct gctttgagtg ttatttctag tacaggtgaa gaatatgagg
    25381 taagtgagac actagaaaaa ggtccagagt ctaatgattc ttcattatct gagatttcac
    25441 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    25501 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    25561 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    25621 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    25681 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    25741 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    25801 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    25861 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    25921 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    25981 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    26041 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    26101 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    26161 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    26221 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    26281 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    26341 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    26401 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaaatcg cactagccac
    26461 atttttcttc ggtttgttag cgacaaatac agtatttgca gatgattctg aaggatggca
    26521 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    26581 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    26641 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    26701 gattgctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    26761 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    26821 atatgatagc caagcagaga aacgagtcta ttattttgaa gatcagcgta gttatcatac
    26881 tttaaaaact ggttggattt atgaagaggg tcattggtat tatttacaga aggatggtgg
    26941 ctttgattcg cgcatcaaca gattgacggt tggagagcta gcacgtggtt gggttaagga
    27001 ttaccctctt acgtatgatg aagagaagct aaaagcagct ccatggtact atctaaatcc
    27061 agcaactggc attatgcaaa caggttggca atatctaggt aatagatggt actacctcca
    27121 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    27181 tgctgaaaat ggtgatatga gaactggctg gcaaaacctt gggaacaaat ggtactatct
    27241 ccgttcatca ggagctatgg caactggttg gtatcaggaa agttcgactt ggtactatct
    27301 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    27361 tgcctatgat tcaggtgctt tagctattaa taccacagta ggtggttact atttaaacta
    27421 taatggtgaa tgggttaagt aatgaagact aattgtaaac tgtgatggat acttaacttt
    27481 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    27541 tactgccccc caaaagttag acaaataatt tatccgaagg atttagttct gtattgcaca
    27601 gggctaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc aatatagtct
    27661 acaatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    27721 tccgatttca gaatcccaaa gaaggactcc atcataccgt tgtcttggct gtttcccttg
    27781 cgtgacatgg atgcttgaat tcccttaccc tcaagaaact gatgataaga atcgtgttga
    27841 tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc tgtgaatgcc
    27901 tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt ataggcgata
    27961 atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt acttgctgga
    28021 atggcaaatt ctgtcacatc tgtgtagcac ttttccattg ttttagagcc ttcaaattgg
    28081 ccttgaatga gattctctgc cttcttgcca acgtctcctt tatgagaaga atattttcgt
    28141 ttctgtcgca ttttagcttg taaattgagt acttttatca agccttgaac tcttttatga
    28201 tttaccagat aaccacgatt tcttagttct aaataaattc gacgataagc ataatttccc
    28261 ttgtgttcga taaaaatgga ttgaatttca gctttaagct cttggtcctt atctgttttg
    28321 tctagctgtt tcaagtgata gtagtaggtc gaacgagcta gtttaatgga ttttagaaga
    28381 agatctaacg aaaactcagt cattaattct tgaacaattt ctgtctttct tctttctctt
    28441 tttcctcctt caatcggagt tctcttaact tttttaggat ggcattctcc gctctcaggt
    28501 actcattttc tgcttgaaga cgttctaatt ctgtcctctc ttcaggtctc gtttttggat
    28561 tacgtcccat tttaggtact ctccctcttg ttttctcaac aatagtatac ccgtttttcc
    28621 tgtattgtgc tagccagtta agaagtatcg tacgacttgg gaggccgtat tcaagagaaa
    28681 ctctatcttt agtccagcct tcatgtcaga ctttatgaat catttcttgt tttaaatcag
    28741 gagaatagta acgatttttt ccttttttga cgaactctat tccgtaacga tcaatcaatt
    28801 taatcatgta cctaagatta gaattgttta tcccaaattt atttgaaagc ttctctaagc
    28861 tatatccttg ttttctaagt tcatagatct gaactttatc atcataagtt aatttcataa
    28921 taaaaacacc ccaaaagtta gattttttct gtctaacttt tggggtgtag ttcatgtaca
    28981 cctgatatga tgcgttttat aatttttaag cctttttgcc cagcctcgtc aaaagtaatg
    29041 ttttgacaca aaatctgtga caaaacttta gttttaaagg tttttaactt tgtatatact
    29101 agttttaaga aaaggaggat gatctaatgg aagaaaaagt atcattgaag gtcagggttc
    29161 aaaaactagg gacatcgctt tcaaatatgg ttatgcccaa tattggagca tttattgctt
    29221 ggggagtatt gactgccctc tttatcgctg atggctatct gccaaatgaa cagttagcta
    29281 ctgttgttgg tcctatgtta acgtatttat tgccaatcct gattggttac acaggtggat
    29341 atatgatcca tggccaacgt ggtgccgttg taggagctat tgctactgtt ggtgcaatca
    29401 caggttctag tgttcctatg tttatcggag ctatggtaat gggcccactg ggaggatgga
    29461 ctatcaagaa atttgatgag aagttccagg aaaaaattcg tcccggattt gaaatgttag
    29521 ttaataactt ctcagctggt ctcgttggtt ttgcattatt gcttttggct ttctacgcaa
    29581 tcggtccagt cgtatcgact cttactgtag ctgttgggaa tggtgttgag gctattgtca
    29641 atgctcgcct ccttcctatg gctaatatta tcatcgaacc ggctaaagtc ctttttctca
    29701 ataatgccct caatcatggc atttttactc ctctgggagt agaacaggta gctcaagctg
    29761 gtaagtcaat tctcttccta ttggaagcta atcctggacc aggcctggga attctattag
    29821 cttatgctgt attcggtaaa ggttctgcta aatcttcttc ttggggggca atggttattc
    29881 atttcttcgg agggattcat gaaatttact ttccttatgt tatgatgaag cctactctat
    29941 ttttagctgc tatggcagga ggtatctctg gaacttttac ttttcaactc ttagacgctg
    30001 gtcttaaatc tccagcttca ccaggttcta ttattgcgat tatggctacg gcgccaaaag
    30061 gtgtttggcc tcatctaaat gttcttttag gtgttttagt ggcagcagtt gtttctttcc
    30121 ttgtagcagc ccttattctt catgcagaca agtcaactga ggattcgctc gaagctgctc
    30181 aggcggctac ccaagcagct aaggctcagt ctaaaggtca gttagtatca acttctgttg
    30241 atgcagttgt ttcgacagac tcagtggaaa aaatcatttt cgcctgcgat gctggtatgg
    30301 gaagctctgc tatgggagct agtattcttc gagataaggt taaaaaagca ggtctagaga
    30361 ttccagtatc taatcaggca atctcaaatt tgcttgatac accaaaaaca ttaattgtta
    30421 ctcaggaaga actgacacca agagctaaag acaagagtcc aagtgctatt catgtttctg
    30481 ttgataattt cttagcgtcc cctcgttatg atgaaattgt agcttcatta acaggagctt
    30541 ttccaatagc agaaattgaa ggagatatac caacttcagc accagtagat agtcaggaaa
    30601 ttgaccttaa ccatattgat gctgtagtag ttgcttatgg taaagcacag ggaactgcaa
    30661 ctatgggctg tgaaacgatt cgggctatct ttagaaacaa gaatattcgt attccagttt
    30721 ctactgccaa aatttcagaa ttaggtgaat ttaattctaa aaacataatg attgtaacaa
    30781 ctatttcttt acaggcagaa gtgcagcaag cagcaccgaa ttctcaattt cttattgtgg
    30841 atagtttagt aacaacacca gaatatgaca aaatggctgc tagaatgtac aaatagaact
    30901 agaggtttct aaattacgaa tgctattaac caaacgagaa gaacaattat tgaaggcttt
    30961 cctacatgta gggaagcttt caatgcaaga tatgactgaa atcttacagg tttcatctag
    31021 aacaatttat cgaactttat cagatttgac agatagcatg gagcaatatg gaatcgaaat
    31081 aacgaagcat gggaaatact atattttgac tggagagttg gatgatttgc cgacagaact
    31141 tgaagtgtta gttgagtata gtccccaaga aagacaagag ttgattacct atcgccttct
    31201 gactgagagc ggttttgtca ccaatgaagc attgcaagag tgcacgaaag tcagtaatgt
    31261 aactattatt caggatattt cagatattga taagcgtctt ttagactttg atctgaaaat
    31321 tgaacgacaa aaaggttatc ggatttctgg tgattcagtt ggtaagagaa gatttttggc
    31381 tattttactg acaaactgta tctcagtagc agatttttca accggtaatt ttgggagctt
    31441 tgatatttta gaagcagata gaactaggct ggccagtcag attgttaata agcaactgtc
    31501 aggttttcca gatatggatg ctaggatgaa gatgtttttt gcgatcttgt tatctcttat
    31561 aggtcaggag caaaacattg aaaattcacc taatactagt aagcaggctt tggaaatttc
    31621 tcaaaaaatt tttcaagctt actctaagca gactgcacaa ttttatagta ttcaggaaat
    31681 tatctatttt gcgagcatct tggatgaatt aatcattaaa cgtcaggaca atccgctctt
    31741 tacggagaaa tttgatggtg aatttttcta caatatttca aatctgattg atacggtttc
    31801 catgtatacc aagattgact tttttaagga caaggtttta ttcaattttc ttttccatca
    31861 tattcggctc agtttaggcg tccctatcct ttttcagggt gaaaatttgc cagaatctat
    31921 ccagatttta gttgaaagga ataaatttct ttatacagtc atcagtcttt tagtgaatga
    31981 tatttttccg aaatatcttc atacagagta tgagtatggc atgattgccc tacattttat
    32041 ctctagctta ggccgtagtc cagagattta tccagtccgt gttttgcttt taacggatga
    32101 acgtcgggtc actagagatt tattagtcag taaaattaag agtgttgctc cttttgtaga
    32161 gttgatagat attcagtctc tagtagatta tcacagtatt gatctcagtc agtatgatta
    32221 tattttatct accaagccgc tgactaatca ggaaatcgat gtaatttcta gttttccaac
    32281 cgtcaaagaa ttgcttgaat tacaggaacg acttcagtat gtacaggcac atcgtacaat
    32341 tgtcgcgcgt gatgctatcg ctccagagaa aagttatgac ttgcaagatt atttaatatc
    32401 tagtagtcag cttttgagtc aatttgagtt ggttcaattg gagaataatc aatcatttga
    32461 gcacacggta gaacaaatca tccaatatca gaagaatgtg agtgacagag attacctaac
    32521 aagaaaattg ttatctcact tccagaatag tcctatggct attcctaata ctggtctggt
    32581 gcttttacat agtcagtcta gcaaagtaac aacaaatagt tttactatgt ttgaactcaa
    32641 actacctatc tccgcattgt caatgaaacg agaggaagaa gaggtcaaaa ggtgtctgct
    32701 aatgctaatg tctaaagaag ctagcgagga agcgagagat ttaatgacag ctattagtca
    32761 gtcgattatt gaaaatcatc tttatacaga gatttacaag acgggaaatc aatccattat
    32821 ttatcagatg ctaaatacta tttttaacga aaaaattaag aaattggaga actaatatga
    32881 aacttgaaaa acatttgatt aagcttaata aacaattttc taacaaggag gaagctattt
    32941 gttattgtgg gcaagttctt tatgagggtg gatatgttaa tgaagactat attgaagcca
    33001 tgattgagcg agataaagag ctatctgttt acatgggtaa ctttatcgcc ataccgcatg
    33061 gaacagatgc agcaaaaaag gatgtactca agtctggtat tacagtcgtt caagtcccta
    33121 gaggggttga ttttgggaat gtatctaacc ctcaagtggc aacggttctt tttggtattg
    33181 ctggtattgg taatgaacac ttggaaatta ttcagaaaat ttctatcttc tgtgcagatg
    33241 tagataatgt tcttaaacta gcagatgctc agtcaaaaga ggaagtattg cgcttatttg
    33301 atgctgttga ataattgaat ttcgtcattt gtcatctagt atatatgtcc ctcaaatagg
    33361 aaaaggagaa attgaatgaa acattctgtt cattttggtg ccggtaatat cggtcgtggt
    33421 tttataggtg aaattctatt taaaaatggt ttccatattg attttgtgga tgtcaataat
    33481 cagataattc atgctctaaa tgaaaagggc aagtatgaaa ttgaaattgc acagaaagga
    33541 cagtctcgta tagaagtaac taatgtggct ggcattaata gcaaagaaca tcctgagcaa
    33601 gtcattgaag cgattcaaaa gacggatatt attactactg caatcggacc taatatactc
    33661 ccttttatcg ccgaacttct agccaaagga atcgaagctc gccgagttgc aggaaataca
    33721 caggcattgg atgttatggc ctgtgaaaat atgattggcg ggtctcaatt tctttatcaa
    33781 gaagtcaaga aatatttaag tccggaaggt ttgacatttg ctgataacta cataggtttt
    33841 ccaaatgctg cagtagacag gattgttcca gcacaaagtc acgaagattc cctttttgtt
    33901 gtggtcgagc cctttaatga atgggtcgtg gaaaccaagc gtcttaaaaa tccagattta
    33961 cgtctaaaag atgtgcatta tgaagaagat ttagaaccct ttattgagcg aaaacttttt
    34021 tcagtcaatt ctggacatgc aacttcagct tacattggtg cgcattatgg tgccaagaca
    34081 attttggaag ctcttcaaaa tcctaatatt aaatctcgga ttgaatctgt attagctgaa
    34141 attcggagtc tcttgattgc caaatggaac tttgataaaa aagaattgga gaattatcac
    34201 aaagtcatta tagaacggtt tgaaaaccct ttcatagtgg acgaggttag tcgcgtagct
    34261 cgtactccaa tccgaaaatt aggctataat gaacgattca tccggccgat acgtgaattg
    34321 aaagaactca gtttgtcata taaaaaccta cttaaaacag ttggctatgc ctttgactat
    34381 cgcgatgtaa atgatgaaga aagtattcga ttaggtgaat tgttggctaa acaatcagtc
    34441 aaagatgttg ttatacaagt tacaggttta gacgaccaag aattgattga gcaaattgta
    34501 gagtatattt aatctttttc gaaaatctct tcaaatcagg ttagcatcgc tttgtcttag
    34561 gcatatgttg ttctatctac aacctcaaag cagtgctttg agctgactcc gtcagtcttg
    34621 tctgcaacct caaaacactg tttgagttat ctgcggtaat ctttctagct tgtctttgat
    34681 ttttgttgtt atttataagg taaaagaagc tggacaaaaa gtcttcaaaa tcggaaaaag
    34741 gcagcctatc gggtgttcaa aaatcttgat aggatgtcct ttattatgga aagccttatt
    34801 ggattttctc ctcagattga gtttttgatc agctttatga gataggtttt gctagagatg
    34861 tagcccatca tgttattttt atggacggtg ggaaaattgt tgaaaaaaat aatgcccatc
    34921 aattctttag tcgtccaaga gaagaacgaa ccaagcaatt ttggaacgaa ttctttcgaa
    34981 tgcgatctat atagtaaaat gaaacaagaa caggacaaat cgatcaggac agtcaaatcg
    35041 atttctaaca atgttttaga agt
//
LOCUS       DAVLZG010000015        34762 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLZG010000015 DAVLZG010000000
VERSION     DAVLZG010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.015"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(224..586)
                     /locus_tag="VYO72_000702"
     CDS             complement(224..586)
                     /locus_tag="VYO72_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1707111.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            594..674
                     /locus_tag="VYO72_000703"
                     /pseudo
     CDS             594..674
                     /locus_tag="VYO72_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1482..2171)
                     /gene="rplA"
                     /locus_tag="VYO72_000704"
     CDS             complement(1482..2171)
                     /gene="rplA"
                     /locus_tag="VYO72_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1707112.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2379..2804)
                     /gene="rplK"
                     /locus_tag="VYO72_000705"
     CDS             complement(2379..2804)
                     /gene="rplK"
                     /locus_tag="VYO72_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1707113.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2936..3073
                     /locus_tag="VYO72_000706"
     CDS             2936..3073
                     /locus_tag="VYO72_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707114.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEIADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(3113..3829)
                     /locus_tag="VYO72_000707"
     CDS             complement(3113..3829)
                     /locus_tag="VYO72_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1707115.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKAQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELLKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3910..4714)
                     /locus_tag="VYO72_000708"
     CDS             complement(join(3910..4344,4346..4714))
                     /locus_tag="VYO72_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1707116.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGVHESNLLRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     SHDMKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(4722..5163)
                     /locus_tag="VYO72_000709"
                     /pseudo
     CDS             complement(4722..5163)
                     /locus_tag="VYO72_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(5165..6202)
                     /locus_tag="VYO72_000710"
     CDS             complement(5165..6202)
                     /locus_tag="VYO72_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1707117.1"
                     /translation="MNQTINYIKELTAIASPTGFTREISDYLVHTLEKLGYQPVRTAK
                     GGVNVTIKGQNDEQQRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPTQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(6300..7625)
                     /gene="brnQ"
                     /locus_tag="VYO72_000711"
     CDS             complement(6300..7625)
                     /gene="brnQ"
                     /locus_tag="VYO72_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1707118.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAVAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7796..7888)
                     /locus_tag="VYO72_000712"
     CDS             complement(7796..7888)
                     /locus_tag="VYO72_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1707119.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7931..8083)
                     /locus_tag="VYO72_000713"
     CDS             complement(7931..8083)
                     /locus_tag="VYO72_000713"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1707120.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDELAALHLEGTHNLPLSQ
                     LADSYD"
     gene            complement(8243..8821)
                     /locus_tag="VYO72_000714"
     CDS             complement(8243..8821)
                     /locus_tag="VYO72_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1707121.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFVAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMSKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8875..10275)
                     /gene="pepV"
                     /locus_tag="VYO72_000715"
     CDS             complement(8875..10275)
                     /gene="pepV"
                     /locus_tag="VYO72_000715"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1707122.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETCADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(10288..10893)
                     /locus_tag="VYO72_000716"
     CDS             complement(10288..10893)
                     /locus_tag="VYO72_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1707123.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            11064..11864
                     /locus_tag="VYO72_000717"
     CDS             11064..11864
                     /locus_tag="VYO72_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707124.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(12042..12875)
                     /locus_tag="VYO72_000718"
     CDS             complement(12042..12875)
                     /locus_tag="VYO72_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1707125.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(12865..14709)
                     /gene="uvrC"
                     /locus_tag="VYO72_000719"
     CDS             complement(12865..14709)
                     /gene="uvrC"
                     /locus_tag="VYO72_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1707126.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(14748..15449)
                     /locus_tag="VYO72_000720"
     CDS             complement(14748..15449)
                     /locus_tag="VYO72_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1707127.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(15528..16760)
                     /gene="murN"
                     /locus_tag="VYO72_000721"
     CDS             complement(15528..16760)
                     /gene="murN"
                     /locus_tag="VYO72_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1707128.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(16765..17985)
                     /gene="murM"
                     /locus_tag="VYO72_000722"
     CDS             complement(16765..17985)
                     /gene="murM"
                     /locus_tag="VYO72_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1707129.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(18097..18876)
                     /locus_tag="VYO72_000723"
     CDS             complement(18097..18876)
                     /locus_tag="VYO72_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1707130.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18945..20606)
                     /locus_tag="VYO72_000724"
     CDS             complement(18945..20606)
                     /locus_tag="VYO72_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1707131.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20781..23003)
                     /gene="recJ"
                     /locus_tag="VYO72_000725"
     CDS             complement(20781..23003)
                     /gene="recJ"
                     /locus_tag="VYO72_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1707132.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            23280..24038
                     /locus_tag="VYO72_000726"
     CDS             23280..24038
                     /locus_tag="VYO72_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1707133.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            24078..24842
                     /locus_tag="VYO72_000727"
     CDS             24078..24842
                     /locus_tag="VYO72_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1707134.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24855..25532
                     /locus_tag="VYO72_000728"
     CDS             24855..25532
                     /locus_tag="VYO72_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1707135.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            25542..26201
                     /locus_tag="VYO72_000729"
     CDS             25542..26201
                     /locus_tag="VYO72_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1707136.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            26459..27649
                     /locus_tag="VYO72_000730"
     CDS             26459..27649
                     /locus_tag="VYO72_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1707137.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27970..28851)
                     /locus_tag="VYO72_000731"
     CDS             complement(27970..28851)
                     /locus_tag="VYO72_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1707138.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28990..30318)
                     /gene="vncS"
                     /locus_tag="VYO72_000732"
     CDS             complement(28990..30318)
                     /gene="vncS"
                     /locus_tag="VYO72_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1707139.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(30315..30971)
                     /gene="vncR"
                     /locus_tag="VYO72_000733"
     CDS             complement(30315..30971)
                     /gene="vncR"
                     /locus_tag="VYO72_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1707140.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(31020..31103)
                     /gene="pep27"
                     /locus_tag="VYO72_000734"
     CDS             complement(31020..31103)
                     /gene="pep27"
                     /locus_tag="VYO72_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1707141.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(31283..32662)
                     /gene="vex3"
                     /locus_tag="VYO72_000735"
     CDS             complement(31283..32662)
                     /gene="vex3"
                     /locus_tag="VYO72_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1707142.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(32714..33361)
                     /gene="vex2"
                     /locus_tag="VYO72_000736"
     CDS             complement(32714..33361)
                     /gene="vex2"
                     /locus_tag="VYO72_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1707143.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(33374..34651)
                     /locus_tag="VYO72_000737"
     CDS             complement(33374..34651)
                     /locus_tag="VYO72_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707144.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9876 a         7882 c         6460 g        10544 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaagga ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taataaaatt
      121 ttattcaatc catctactca ttcccaaaag gttgctgtat aatgcaagac atttttctta
      181 ctgattttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactatt gaaacaatag aacgtaaata atgataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatgact ataatcatct gtatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaactgatt aggaaattta aaccaacttc taacaatctg ttatactcaa
      601 tgaaaaccaa agagcaaact aggaaactag ccgcaggttg ctcaaaacac tgttttgaag
      661 ttatggatag aactgacgta gtcagctcaa aacactgttt tgaggttgtg gatagaactg
      721 acgtagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaacc
      781 atacacacgg caaggcgacg ttgacgtggt ttgaagagat tttcaaagag tattagaaag
      841 ctcgatggac tattccagat tcattccact agatttcgaa atcgagtagg ggataatctc
      901 tagcccctct cacaccaccg tacgtgccgt tcggcatacg gcggttcaac taacttttaa
      961 cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt caaggactgg
     1021 ttttgatata gcacgtttaa gtaccgactt ctgagctact atagtagatt gaaactagaa
     1081 tagtacacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct gaacgattcg
     1141 tcctattctt atttcatttt attataattg atagtggtcg ccccagccag ataccttatc
     1201 cgctatatac gccttattat cacgttcctg ttcgtagagc cacgatttcg ctatcccttc
     1261 ctctgacgat tcttatttcc agcgtcagac ttaaaacggt ctatccccag accgttttaa
     1321 tccgctacct cacgatagtc agacttggga atcgctattg ggttcaccgg tagtaggtgc
     1381 ccaccgagga cttacacctc agatatacga catgcccgtc gtacatcaaa aaaagttgag
     1441 acatagtgtc ttcaactttt ttacattact ttaactactg attaaagtga gtttacgtca
     1501 actttgatac caacaccttg agtagttgtg atagtcaagt ttgttacgta agttccttta
     1561 gctgtagctg gttttgcttt ttggattgtt tcgttgaaag ctttaaagtt ttcaaccaat
     1621 ttttcagctt caaatgatac tttaccgatg attgcttgaa cgttacctgc acggtcagca
     1681 cggtaagtga ttttaccacc tttagactct tcaactgctt tagcaacatc cattgttaca
     1741 gtaccagttt tagggtttgg catcaagtta cgtggtccaa ggacacgtcc aagacgtcca
     1801 acaagagcca tcatatcagg tgtagcgata actacgtcga agtccaacca accgtcgttg
     1861 attttagcaa caaggtcatc ttcaccaaca aagtctgcac cagcagcttt tgcttcttca
     1921 gcttttgcac cacgtgcgaa aacaagaaca cgtgaagttt taccagtacc gtttggcaat
     1981 accattgctc cacggatttg ttggtcagct tttttaacgt cgatgttcaa gttgtaagca
     2041 acttctacag ttgcgtcaaa ttttgcaaag ttagtttctt ttgcaagtgc tacagcttct
     2101 tctacactgt atgcttttgt gctgtcgatt ttctcaagag cagcacgaag ttgtttgctt
     2161 tttttagcca ttttctattc tccttgtaag tggttcaatc gattttcatc tcccacgtca
     2221 cttctcgaaa tgatgaagtc ttgcgggttt tcagtctact atttttctct tcctacggcc
     2281 ttaagctccc ttgctgtacc caagtacaag gctcagtcac ttgcctagta tgaaaagcaa
     2341 ctaatagact gctgtgagat tttctactgt gttattgatt agtcaacaac agtgaatccc
     2401 atagaacgag cagtaccttc gatcatacgc attgcagact ctacgtttgc tgcgttcaaa
     2461 tctggcatct tagtttctgc aatttcttgt acttgtgcac gagtaactgt agcaacttta
     2521 gttttattag gtgtacctga tcctttttca acacctgcag cttttttcaa aagaacagca
     2581 gctggtggtg tttttgtaac gaaagtaaat gatttgtctt cgtaaactga gataacaact
     2641 ggaatgatca taccagcttg gtcagctgta cgagcgttga actcttttgt gaatcccatg
     2701 atgttgatac cagcttgacc aagagcaggt ccaaccggtg gagctggtgt agctttacca
     2761 gcagggattt gcaattttac aagtttttcg acttttttag ccatttttaa atcctccttt
     2821 gtggttttgg cggtaattag agatttttac ctcccacaag tatgtttttc acatacccat
     2881 ccattataca ctatttatct ggaattgcaa gagaaaagtt tattttttat actcaatgaa
     2941 aatcaaagag caaactagga agctagccgc aggctgctca aagtacagct ttgagattgc
     3001 agataaaact gacgaagtca gctcaaaaca ctgttttgag gttgtgaata gaaccgacgc
     3061 agtcagtagg taaggcgacg ctgacgtggt ttgaagagat tttcgaagag tattaatcga
     3121 cgtagtctcc gccttcaaag ccatagtatt cttccaaact gagaccactt gcagcaattt
     3181 ctttagcttc ttttcctaca taacgcaggt gccattcctc agccatatag cctgtttcct
     3241 tttccttgcc tttgagataa cggacaacaa agccataatc agctgcatga tccaagagcc
     3301 attgggctgc tttttcttct gtcaccaaat caccatcagt cccaatcaca tcaaaggcca
     3361 agcctgtctg gtgctcacta tagccaggtc gggcagagta acggtcagct gctgccttcc
     3421 catcttggtt aacataatct tgatagagct tggtctgagt ttcataactt ctaaaaccac
     3481 tgtaatgatc gctaatcggg aaacctgcct cttgcattgc tttgatgagt ttgagcaatt
     3541 ctgccttggc tgtcggattt tcacctggat tgtagtcttt agacaatgga tagtgtttat
     3601 tggctacgat gatttcatcg tatttccctt ggatgctgta gtagtctcct ttgttaacca
     3661 cttctgcttt tttctgggca gctccttgag ccttacttcc tactgttcca tcagctttag
     3721 ctgtttgttc tgttttagct gctccatctt cattttttgc tttttcttgt gaacaagctg
     3781 ctagactcaa ggctagcaaa gctgtcaaga ctaggtatct ttttttcatt tctactcctt
     3841 tatttctaat agtttatcta cttctaacga taaacgtttg actaatcttt taatagactt
     3901 cctgcaaaac tagaatccta gttcatgatt gataatacca gcaatcaaat tcattcgtaa
     3961 tccgaagcgt ttacgatgat ttcgataggt tgttgaaaac attttaaacg tttttacttt
     4021 ggcaaagatg ttctcaacct tgcttctctc cttagatagc gcatggttac aggctttatc
     4081 ttcagctgtt agcggcttga gtttgctgga tttacgtgga gtttgtgctt gaggatatat
     4141 cttcatgagc ccttgataac cactgtcggc caagatttta ccagcttgtc cgatatttct
     4201 gcaactcatt ttgaacaact tcatatcatg actatagttc acagcgatat ccaaagaaac
     4261 aattctccct tgacttgtga caatcgcttg agccttcata gcgtgaaatt tctttttacc
     4321 agaatgattc gctaattctt tttttagggc gattgatttg tacttccgtc gcatcaatca
     4381 ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt aacaccactt tgaacaagag
     4441 ttacttcaac ccatcggctc cgacggagta agttgctttc gtgaacacca aaatcagccg
     4501 caatttcttc ataagtgcgg tattctcgca catattgaag agtggccata agaaggtctt
     4561 ctaggcttaa tttaggtttt cgtccacctt ttgcgtgttt aagttgataa gctgttttta
     4621 atacagctag catctcttca aaagtcgtgc gctgaacacc aacaagacgc ttaaatcgtg
     4681 catcagttag ttgtttactt gcttcatcat tcatagaact actataccat attttgtttc
     4741 gcaggaagtc taatctcatc cggttttgct tggcgggttt ctgcggtcat tttttcaaaa
     4801 gggacccacc agactggccc acagtccttg agaccgtggc cattcatatc acctcttcgt
     4861 ctagggaaaa ggtgccagtg gagatgggca tcgccatttc ctagaagttc aatattcatt
     4921 ttctcagcag taaagccctt ggcaactgcc tcttggacta aactcatttc ttctagaaaa
     4981 tggagtcttg tgtccttttc taaaatggtg caattccgtg acatgttcct tggctagaaa
     5041 gagactatag cttgcaaaat actgatggtc tccaatcaca agatagcctg ttcccaactc
     5101 tttgacaaag tagggatttt ctcccttctt gatgagctca attctctggc aaataaggca
     5161 catatcaatc tactaaattg cttctaagat aggcatcgac cattcgttct gttgcgacca
     5221 ccgagtcaat atgagtgcgc tcataagaat gactagactc gatacccgca ccaagaaggg
     5281 catgcttgac ctctgcccct gcagacatag ccgctgaagc atccgaacca taaaatggat
     5341 agatgtccag cttaaaagga atatcttgct ctttagccaa ggcaaccaag tgttgacgga
     5401 agtcatagtg ataaggacct gaagcatcct tgacacagat agatactgtg tactcatctg
     5461 tctgctggtc atctcccatt gcccccatat cgacagctag atattccacc acttgagttg
     5521 gaatattgga attagcaccg tggcccacct cttcgaaaac tgaaaaagca aaatgagttg
     5581 ttactggcaa ttcaattccc tcttccttat aaacacgaag aagattgagc aaaattgctg
     5641 cgctgacctt gtcatccaag tggcgagact tgataaaacc agtctctgtc acaacagttc
     5701 gcggatcgaa actaataaag tctccaacct caatacccaa ggcgcgcgtt tctttttcat
     5761 tggttacttt tgcgtccaaa cgcacttcca tattgtcctg cgtacgttct gcagttcctg
     5821 catccttgta gacatgacaa gaagtctggt ggatgaggat ggtcccagat accgtttgac
     5881 ctgtgctagc cacatgaacg gtacagtttt ctccttcaat catgttccaa ggaaaaccac
     5941 caatacgatc caatttgaga cggccatctg gtttgactgc acgaacaata gcacccagcg
     6001 tatccacatg ggctgtcaca tagcgttgtt gttcatcatt ttgaccttta atggtcacat
     6061 tgacaccacc cttagctgta cgaacaggct ggtaaccaag tttctctaaa gtatggacta
     6121 gatagtctga gatctcacga gtaaagcccg ttggagatgc aatagcggtt agttctttga
     6181 tatagtttat agtctgattc atttcttcac ctctttcgct acctattata acacatttat
     6241 catcggataa aaaaagaaaa tcactcctgt agacttggct acaaaagtga tttaagtgat
     6301 tattccattt caaaaacatc gctttcttgc ttgtttggta gaaccaatga gagcaagatt
     6361 ccaacaatgg ctggcaccaa ccatgggaga gatgccttgg caaaaggaag aacgctaaca
     6421 agatttgcaa gaaactcaac cttaaacgag cttcctagta cgcttgcaat ggcaataact
     6481 gtaaccacag caattgtcaa ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca
     6541 atgacaatca taacgatagc aatcgtgatt gggtacaaga taaccagtac tggaattgag
     6601 tacttgataa tcgcatcaag acccaaattg gcaatagcaa atccaatcaa ggtaaaggct
     6661 gtcgcataaa ccttgtagct gatttgtggg aagcgctcat taaagaactc agctgttgac
     6721 acaatcaaac caacagtcgt tgtgaagcag gttacggtaa ccatagctgc aaggaagagt
     6781 tgagctgttg agccaaagat ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt
     6841 ccacccttca tcgcttcagc tggtactggg aaatgatttc caagaaaacc taaaccgatg
     6901 taaagagcgc tgaaggcaag ggcaacaacg ataccaacaa cccaaatagt tgaaatgtat
     6961 tctttcttac ttgaaaatcc aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc
     7021 actgaggcaa gggcgtccaa ggtattataa ccttctagga aacctgtacc aaaggcagaa
     7081 gcttgataag cagctgaagc agcttgagga cttgttccac catatttgat agctcccaga
     7141 acgaccaaga taacaatcaa aattgcaaag actggcgtta aaatacgtcc aatgcggtct
     7201 aagatttttg atggattaag cgaaatcaaa taggctaccg caaaatacag aaccgtaaat
     7261 acaatcaagc caagtccttt atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa
     7321 gctgttgtag cagtacgtgg ggtagcaaag aatggaccga ttgacaagta aagaactgag
     7381 aggtaaagag tcgcaaacca aggcgctatc ttcgttgaaa tctcgtagat atatccttta
     7441 ggatttagcg ttccaataat aagggtcaag acggcgatac caacgcctga aaagacaaaa
     7501 cctgcgatgg caggaagaaa atgttctcca gatagagcac ctagagaagg cggaaaaatc
     7561 aagttccccg caccaaaaaa tattccaaac aggagcaaac ctgttagggt acctttttta
     7621 gccataaaaa tctccttcat atttataaaa tactgaccta gtataccacg attaggagtc
     7681 tgaaaaaagc atcacgaggc aaatattaaa tgttttcaat tttcttaaaa ataagaatta
     7741 tctaaaaaca aaactctcct acccagtcca caccaagtag gagaaatgca aaattttaaa
     7801 gttcttcaaa ggctaacatg ccaccctgga cattgataac attataacct tgttctaaca
     7861 ggaattggca agcacgcgcc gatctcattc cagatttgca aataatataa tgcaagcgat
     7921 ctttgtccaa ttaatcataa ctatcagcca attgactaag cggtaggttg tgggtacctt
     7981 ctaaatgaag agctgcaagc tcatccactt ctctcacatc cactagagaa agctggtcgt
     8041 tttggtaaag ctgataaaat gcgtcaaagg ctatttcttt cattcttttt cttctaatac
     8101 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt
     8161 cgtcagtttt atctgcaact tcaaagctgt actttgagca gcctacgact agcttcctag
     8221 tttgctcttt gattttcatt gactataaaa tggttttaat tctttttttc aaatctggca
     8281 ctacttctgc ctcaaaccaa ggatttttgg acatccagat ttgatttcgt ggtgatgggt
     8341 gaactagcgg aaaataggct ggcagatagt ctttatagtg tttcaccctc tccgttacct
     8401 tcccactgat tttctcctgt aaatagtagg cttgggcata ttgcccaatc aagagggtta
     8461 actgaatatc aggcaattcc tgtaagagct gcggatgcca tttttctgca aaatctgtac
     8521 gaggcggaag atcacccgac ttgccatgtc ctggaaagta gaaatccata ggcaaaacag
     8581 caaaataacc tgaattgtaa aaggtatctt catccacacc tagccagtcc cgcaagcggt
     8641 caccactttt atctttccag taaaggcctg cttcttgagt tttaagtccc ggagcctgac
     8701 cgatgatatt gatgcgagca gtttttggcg ctacaaagag aggctcaatg ccacgctctg
     8761 tatagctggc attctgcgaa tccgccatga tagcctgttt gattctttcg atttgagaca
     8821 tctactttcc ctccaaaaag aagtccaagc ataagatctc agacttctat cgttttattt
     8881 gatcaattcg taaatagctt cggcataaat tgctgctgct cggaagagat cgtccaaggc
     8941 aataaattca ttggcttggt gcatagtatc aattgagtct gggaacatag caccataggc
     9001 aactccgcgc tctaacaagc gaccaaaggt tccaccaccg atgacttgtt catgaccttg
     9061 taggcctgtt tgtttttcat agacattcaa caaggtttgc acaagtggat cttccattgg
     9121 cacatagtga ggggtatgac catgttctga tagactgaca gaagcaactg gcaagttttc
     9181 taggattgac ttgatttgtt ctggacttgt tccttttgga tagcggatgt tgagggcaat
     9241 ggtattatca gcacatgttt catcgaagcg gaagacgcct gcattcatag aaagggcacc
     9301 catcttttca tccacatgag caatcttgag actttcaccc tcatggtcgt tcaagagaat
     9361 tttaccagtg atgtcaaggt attctttggc tggaccagca aagtcaaact ggctaaggaa
     9421 gagggctagg taagtcgcac cattgacacc tgaagcaggc atagcaccgt gggctgattt
     9481 accaatgatc gtcaccttgt atttgccagc ttcttcttgg agttctcctc taagtttgtg
     9541 ttctgcaaca aaggcatcta gtttagcttg caagtcagcc aaatcacctg aaacgactgc
     9601 tgttgctgat tctggtacca tattttcacg taaaccacct gtaaagctgt gaagacgggc
     9661 agcacctgta ttttctcctg caaagtggag gtattccgtg atatttcctt tttcaccatt
     9721 gatgataggg aattcagcgt ctggagagaa accgaaatct ggtttggcaa gtcctacgtg
     9781 ctcaaagtag tagtccatat ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg
     9841 aactttctta gaagttggaa gacccaattc tttgatgatt ttcaaaccat agtaacaagc
     9901 tgttgtagga cccttatcgt ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt
     9961 tggtgtgtaa ggatctgtat cccaaccgct accagctgga accacgtcca tatgggcaaa
    10021 gattccgaga acttcttctc catcaccaaa ctcaaaatgt cctgcatagt tatcaacatt
    10081 tttagttgga taaccatcac ggtctgcgat ttcaaggaat ttttccaagg cttttactgg
    10141 accaggtcca aatggatgtt gggcatcagc cttgctatca tcacgttctg agttgatttc
    10201 caaaaggcta aacaagtcag ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa
    10261 atcaattgct atcatttttt cttcttccta tcttttttcg atgatttcat ctactggcaa
    10321 gcggtagctt ggttccaatt tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg
    10381 gaaacggtct tcgatttcca aaacttcatt aacttttgat ttgtcaaaac caaggataat
    10441 attggaacca attccttggt ctgtaagagc gagaaccaag ttcatagcaa ccaaacctgc
    10501 attgagtgct aggtagtcgc tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa
    10561 atttttcatg aagtattgaa gttgttcttc tgagaaattg ttagcaccac caactcgggc
    10621 aatcttacga gcgcgtttgg caaggtctgt atctgtaaat agggcaatgg ttacaggtgc
    10681 tgatgatacc tgttcaaaat tggaaccata agctaacttt gccagttcag catttttctc
    10741 acataccacc acaaatttcc aaggctggct gttgtgggcg cttggcgcca aggttgcaat
    10801 ttcgatagcc gtacgcacat cttttggatc aacaggctta tcagtgaaat gcttggtcgc
    10861 atgacgtttt ttatttaatt caagaaattt cataatcgat ttccttttct aattctactg
    10921 cttccattct accataattt gaaagagctt gcagggattt ttcatgatta agtttttcta
    10981 tcacagacat aaaagatata tattggttta tcaggaaagt ttctgataaa ctagcaagta
    11041 ctttacattt gaatggagac agtatgaaaa aatttagcct attactagct atcctaccat
    11101 ttttggttgc ctgtgggaat caagctacac ccaaagagtc cagctctcaa aagacaatcg
    11161 tccttgctac agctggcgat gtgccaccat ttgactacga agacaagggc aatctgacag
    11221 gcttcgatat cgaagtccta aaagcagtgg atgaaaaact cagcgattac gagattcaat
    11281 tccaaagaac tgcttgggag agcatcttcc caggacttga ttctggtcac tatcaagcag
    11341 cagctaataa tttgagttac acaaaagagc gcgctgaaaa atacctctac tcgcttccaa
    11401 tttccaacaa tcccctcgtc cttgtcagca acaagaaaaa tcctttgact tatcttgacc
    11461 agatcgctgg taaaacaaca caagaggata ccggaacttc taacgctcaa ttcatcaata
    11521 actggaatca gaaacacact gataatcccg ctacaattga tttttctggt gaggatattg
    11581 gtaaacgaat cctagacctt gctaacggag agtttgattt cctagttttt gacaaggtat
    11641 ccgttcaaaa gattatcaag gaccgtggtt tagacctctc agtcgttgat ttaccttcta
    11701 cagatagccc cagcaactat atcgttttct caagtgacca aaaagagttt aaagagaaat
    11761 ttgataaagc gctcaaagaa ctctatcaag acggaaccct tgaaaaactc agcaatacct
    11821 atctaggtgg ttcttacctc ccagatcaat ctcagttaca ataacactct tcgaaaatct
    11881 cttcaaacca cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct
    11941 agcttcctag tttgctcttt gattttcatt gagtataaga tatataaaag cgattggact
    12001 accaatcgtt tttagtttgc attggttatt ttaggaaact cttacaaaaa atcaaaaaaa
    12061 ttcttcacat cctctacata cctatgcttt tctattaagc ttgctaatag tttcagattg
    12121 tgcctctgat agttatcttc acgacgtagt tcttcataca tttcgataaa gggaagcccc
    12181 ttggatttgg ccaattctaa ctcagcctcg taatcataag caactttacg aaattggata
    12241 ttgagtaatt ccccatcttc aacctctatc acggcatact gggcacggtg attttttaac
    12301 gcctcccaat taaaataggg catgccaatc gaccctggat tgatgatttg ttgcccttta
    12361 ctgccgtagc gaagcaactg cttgtgaaca tgaccataaa ctgccacgtc cgtttccgca
    12421 tctagcagtt ggtcaaattt ctctgtatca ttctcaacta gcaagtcacc accatagttt
    12481 ttgtcaggta aattatgaga gatagaaaag cgcaatccgt caatttcttt cttttccagc
    12541 aaaggcaagc ttcgtagcca gacaatcgtt gcaggatcca ttcgctccat caaaaactgg
    12601 gtcatgcgca ttgactggat ttctttcgga tattccaaac catattcgcc atccaagacc
    12661 tcaaggacac gatcatccca attgcctcga acacttgctg tgataggaag gtcctttagc
    12721 agggcgacta agtcatttgc gcctggacca ggaagaaaaa tatctccctg aagccaatat
    12781 tcactggccc cttgattttt agcatctgca atcactgctt ctagcgccgt cgcattgcca
    12841 tgaacatctg ataaaattgc gattttatgg ttcattgtgg tttccttccg tttggtaatc
    12901 tactctttct tctgctactt gaggcaaggc ttctccctgc gggttcaact ttctttgcac
    12961 agcctctgca acgactctag gtaccccaac ttcgacaatc tcatccacac tggcttcctt
    13021 gattttggtc aaagacttga aatgcttcat aagattctgc ttgcgtttag gtcccagacc
    13081 gtcaatccca tccaattgag atgagaaaga atttttggag cgcagttggc ggtggaaagt
    13141 gatagcaaag cggtgcacct catcttggat gcgttggagg aggaaaaatt cctgagaatt
    13201 gcgagacaag tccaccacct caagcggatc tccaaagagc aattcatggg tttggtgctt
    13261 atcattcttt tgcagcccag caattggaat atccaagccc agttcctctt ggatgacttg
    13321 cttagcaata ttgacttgac cttgcccccc atcaatcaca atcaaatctg gaggagtcaa
    13381 agcctcacgc tgtactcgac catagcgtct gcgaatgact tctctcatac tagcatagtc
    13441 gtccggccca acaacggttt ttatcttgta cttacggtaa tcttttttac ttggcctgcc
    13501 gttaacaaag accaccatgg ctgaaacagg actggtcccc atgatgttgg agttatcgaa
    13561 ggactcgatg cgaactggag tcggaatttg gagcaaacgt cctagatttt caatagctcc
    13621 ttgggtcttt tcgactgatt tttctagcag attgaacttc tgctctagac taacacgagc
    13681 attttttatg gctagattga ccagctgttt tttctctcca cgttggggtt tgagaatctt
    13741 ggtatccacc aaagccttga cagcttcttc gtcaatatcc tgcggaatca gtacctcatt
    13801 gggaactagg tgagattttt cttgatagaa ttgtcccaca taggtcaaga aatcctcatc
    13861 tggatcattg aagtagggga agagattgac atcgcgctcg atgagcttgc cctgacgaac
    13921 aaagaaaacc tgcacacaca tccagccctt atccacatag tagccaaaga catcgcgatt
    13981 ttggagatcc ttagccatga cccgttgctt ggttcgaagt gttccaatgg cctgaatcag
    14041 gtcacggtat tccgctgccc gttcaaactc catactttgt gctgttactg ccattttact
    14101 cttgagatca tcgatgattt tgtcatcctg acctttcaga aaatcagaca cctcctgggc
    14161 catggacttg aaataggcct cgtcattctt acagatggtg tgggccatac attggccgat
    14221 atggtagtaa aaacagacct tagagggcgg gttggtacat tttcgaaaag ggaaaatcct
    14281 atctagaagt cgcttgattt cattggctgc ccccacatct ggataagggc caaaataaag
    14341 accaccgtcc tttttgacct gacgagtaat gataagccgt ggatagtgct cattggtgat
    14401 tttgataaaa ggataagact tgtcatcctt gagcatgata ttgtacttgg gcttattttc
    14461 cttgatcagg ttgatttcca gcagaagcgc ctcaatatta gactccgtaa caataaattc
    14521 aaaatccaca atttcagaca ccaaggcctc tgttttggta tcatgacttc cacggaaata
    14581 agacctcacg cgattacgca gatttttagc ctttcctaca tagataatgg tgccgttttt
    14641 atccttgtaa atgtagcaac cagggctggt cggcaagagc tctagttttg gtttaatcaa
    14701 gttgttcata gttccattat agcaaaaaag tagggaaaga tagtacccta ctcattagtc
    14761 tcatatattt ttcggaggtt tgcaacatcc tcttcctgga taccataaaa ggaacctgct
    14821 ggttgcatga cagacttctc atctgtatgg tccaagccaa tcgcatgacc taactcatgt
    14881 tctgccgtat ggacaaggcg ttcataggaa tagccatagt atggattgga caaataataa
    14941 tgattcaacc gcaccgttac ggacaagaat tgccctgtta agagattagt ttgactttcc
    15001 gcctctcctg ccacaggagt gcctccgtcg ttcatctccg tagccgtaat atccgcctta
    15061 ctagactcag tcacgagttc aaagttaaaa gcaccagttt gattccagtt ctggattgct
    15121 tctaaataag cctcttgaaa gcgtgaatcc atctgcggat ccaggtaaat acgagcagag
    15181 gcctgtggcc accttccttc agaatgctgg tgactatctg tctggcttaa cttaggcagt
    15241 tgccctgttt tctcccattg gtcaatactt tgttgaccaa tttttactga ccgttctgct
    15301 tgctttagcg ctccttgaaa atccccgttc agataccaga gaagtccgaa agcaagcaca
    15361 cataagagca caactatcca aaccagacgc caaaacaaac gccacacaaa agaaaagaaa
    15421 gcccctatca aacgaaaaag ccagcgcatg tctctccacc tttctagcaa ataaaaatta
    15481 ttttactaaa agaagctaaa agaaatctaa atactgactt tttcatctta acgtcctact
    15541 atttttttga gtaactggat agctttgtat tttaaaggag atggatggta acggaaagta
    15601 cctgctttgc gtacaatata gccattaaaa ttctgtttaa aacgcaaaac accatcactt
    15661 ccatcaaaaa tcccttgaat gcctaggaag ttgtatttag gtattccacg ttttatgctt
    15721 tccaacataa catatttttg aagcagtgca ggggcataga acttattaaa ctcagtgtag
    15781 gaaccactaa agagataagt cgtttcctga ggcatataaa caaataaact cccagctaaa
    15841 acaatatctt cttctccata tttttcaatc aagtctcgcg cttctgcttt tcgaacttca
    15901 aacgtttcaa attgactaga atattctctc agttgatttt gttttttctc agaatgagga
    15961 tttttactca aatcaagtcg caacttgtcc aagttttctt ctagtttatt ttgttcacct
    16021 tgcaatttgc tcatatagtc cgaaaaattt aagcttgcta tgagaaactc cgcttgttct
    16081 ccaaaagtat cataaaaatg ctcataatat tctaaacttt tatcactata ttctctacgt
    16141 tcagaggttt cttttgttat attcttaaaa atcgatagtt cttcacgttt taactttttc
    16201 aatcgaatgc caaaggtttc agcctttttc accaagggtt tacccttttt gctaaaactt
    16261 ttaagcaaac tcttttcagt taattcagtt aaatctttat agtataacca atctggttct
    16321 ccacctgggt aacctgttgt taagccatca aattgataac ctaaatcagt caaaccttga
    16381 ataatacttt ttttctcagc atctattgga ttaccttggc tatcaaaagt ttgataagtt
    16441 tcataaggtt ttacaagcaa ctctaataca ccattttgct tggcatattc ttttaactct
    16501 gcataaaaaa ctggaagagc atcttgttgg gtataaatcg gccccgaatt gagttccata
    16561 tgcagaccac ccagcatggg caagctataa accagagctg caacttgaat ttctccttct
    16621 tgtttcaaag caagataaac aattcgagcc cctctttttt ctagcaaatc ccccatctgg
    16681 acagattgca taaaggaacg agaagaaacc tgatcagaat aagtctgaaa ctcttctttc
    16741 gtgagtgttg ttagtgccat atacttactt tctatgtttt tttcttaatg ttttacggaa
    16801 atcaagagca agtcttaaca gaggatagag aggatgagtg ggcattgtaa attcacccaa
    16861 gtattcttca atcgttggat taaatttttc cttaaaatga taaagtccac cattgagaga
    16921 gttttcaaca ccacctaaat tttgccagac catacctcgc tcaaaggcat agcgagccgt
    16981 ttcataccat gttaaaattg gtgcattgta acgtttaaaa tcatcatcca taccagcata
    17041 tatattgaca gaggtagtac caaattccaa actcaaagta gccgctaaag gaactctcgc
    17101 ttgacctaca tctatatatt cctgcaagaa ggtcaattcc tctaacaaac gttctttttc
    17161 cttcttctgc gcttctactt ttgaagttcg agtcgactca gtaaaggtct cttccaaggc
    17221 tctatttttc gctaactgtt cttctaattc ttgcgaacgt ttagaaacat ccaaggtggc
    17281 caaggtgata taggccttgt ccttaaaatt atctaacaat tttttataat aggcttcatt
    17341 cctcaaatga atctcttttc gcttctcagt ttttttcatc aactccgaaa atgaatctaa
    17401 tagttccagt ccaccatatt gaatctcaag ccctttgttt cgtgctgttc gaatagcctg
    17461 ttttgttgac ttggaaagtt tatcttcttc aaaattttcc ttgtatattt tcgcctgaat
    17521 acgaggttga atggtgtctc ccatttcctc cgtttttcct gaccacctta ctcccatttg
    17581 ttgcaaacta tcaataatag ccagattttc aggaaattct gtcttttcct gattgattaa
    17641 actttgagat aggcaaatac ttgggtcaaa agtcacaaaa accgctctct tactgcgagc
    17701 ataggactta atagactgaa tggcaaaatt caagagttct ttatccccat aatccaatat
    17761 aggtcctctt gggatgtaaa acattttata gcctagcgga agagttctaa tcaaaatact
    17821 agctgtcgcc agtaattttt cttccctgta aacaccaaac ttctcatgtt gccaattaga
    17881 cttaacttcc tcccaagcac tactttgtaa tacattggct aattcatgtt ctttgacaaa
    17941 ctgatcatat tctaatgtgg gaatgccaat ttgataacgg tacatttcct actctctttc
    18001 ctccagtatt ttattactat tctactactt tcgtttgaaa agtctagtga aaacatattt
    18061 tattttagtt ctactccccc tatgctgaag ttcaaactaa gtcagtctct cttctaattt
    18121 gaaatcaatt ggtagggttg ttaaaaaaac ttccaattgt ttttcccagt agtaccactc
    18181 gtgagttcca gcactatggc tataggtcac atcaaaacct agttttttga gatttttcac
    18241 tgcgagatta ttggcttcgt acaagaaatc ctgttcgcca caccacgccc aaagtttggt
    18301 ctttttatcc gattttttag ccagactttc aagagaatag ggactagttg tccagtctct
    18361 aatctctcca aaaacacctc tccagtaggc tggacttccc agattttgac tttcaggaga
    18421 aaagttttga aagctgaggg cacctgaaaa actagctgca tgagaaaaac gatttgtcgt
    18481 aagagccagt ttgaagcagc cgtagcctcc catagaaaga ccagcgataa aggtcttttc
    18541 acgcttgcta gtcatattag ggaagaagcg tttcagaacc tgcggcaatt cctctgctag
    18601 agccgtgtag tagtcaaaac catactgggt atcggtgtac caaccattgc tggtattggg
    18661 cataacaacg atgagattag ttcctcgaag caagcgttct acattggtcc gcttaagcca
    18721 actattatga tttccagaca tcccgtgcaa aaggtacaag acgggaatat cttcacactc
    18781 tggttcttcc actcgattgg catcagggta gaggacattc accccccact ccatatccaa
    18841 tacttgtgag taatactcga ttttcattac tgccatgatt ttctccttct atttttctat
    18901 aagaaaaagc cgaaactcga ctttctctct gtttatttca acgattattt tgcttccatg
    18961 actactggta aaatagctgg acgacgcttg gtttggtcaa agagatactt ggtcaaatta
    19021 tctcgaacct tccctttaag atctgcccag tcaaagtcat ctccttgaag ataatcttct
    19081 accgtttggt taatcaattc tgaactttca cggagaatat cgcgactctt cttgagataa
    19141 acaaatccac gcgtgtgaac acgagcccta gccacaattt tcttctcacg acggttgact
    19201 gtaatagcca cgatgaaaat tccatcctct gacaagacct tacggtcacg aagaacaaca
    19261 tttccaacat caccaatggc attcccatca atcaagatat ctcctgctga aaccgatcca
    19321 gctggaacaa agtctccatt ctcgtaagcc atggtcgtcc cctttttagg aatgaaaatg
    19381 cgttctggca acatcccaac tgccatggca gccttagcgt gagcatccaa ctcacgatac
    19441 tccccttgga cagggaagag gtacttaggt tgcaaaagat tgatcatcag ctgcaaatca
    19501 cgcacatttc cgtgccctga tacatgtaaa ctttgggtaa tcaatttgac aaccccacct
    19561 gcctgataaa tcatattttc cacacgcgca acaaaggctt ctttagcaat agacggagcc
    19621 gtagcaatat agaccaggtc cccatccttg atttctacat aacgatggcg accaatcgac
    19681 atcttacgaa gtccattgat aggttcaccc atacgacctg tctcaagaat aatcaactca
    19741 tggtcttcaa agcgagacat atctttaggc ttaatcaaga gaatttcgtt ggctaaagac
    19801 aacttcttaa gacgaatcgc tgtgcggacg atattttcaa tatcaaatcc tgtcaagacg
    19861 atacgtcgac ctgttttatc cgcagcgtca aaaatctgct gaatacgaga aagattactg
    19921 gaaacagctg caacgatgat acgaccttcc cagtcagcaa tagtttgggt aatttcatcc
    19981 ctaacttcac tttcactagc cacctgaata ttgctgtctg cattggccga atcactgagg
    20041 agagccagga cgccgtcacg accaatctct gccaaacgag caaaatcagt tgcataagat
    20101 tcactagccg tttggtcaaa tttgaagtca cctgtataaa cgatgcttcc ttccgatgtc
    20161 ttcaagacaa ttcccagact ctctggaacg gagtaagtcg tagggaagaa ggaaaccact
    20221 gtcccaccaa aatcaatctc cgtattctca tcaatgacat ggaaatcatt aaatttctta
    20281 acggcatcat ttcctttgac aaagagcttt gccaactcaa tggtcaactc agacccaaat
    20341 acaggaactt tagcctctgc caagagataa ggtagagcac caatggcatc cgcatgcccg
    20401 tgggtcaaga aaaccccagc aatacggtcg ctattttcaa aaaggtaatc catgtttgga
    20461 atcaccacat cgacccctaa ttgttcattt tcaggatatt ttaaccctac attcaaaaca
    20521 aaaatggact ctccaatttc agcaatgtac atattttttc cattctcacg cacaccacca
    20581 agtgttgtta aactgatatt actcattttt cctccaaaat cttagtttat cttgattata
    20641 gggcaattct accctcttat tctaaaagtt ctgatacttt cagccgaatc ttttcctacc
    20701 attataccat ttttttgatg attttcaaaa tgaaggtctg ttttcaaaaa agagttgatt
    20761 tcccaactct ttcctaactt ctactctttt tccatcaaaa aatcataaat ttcttgcacc
    20821 gtacccagcg ccatcatttc ttggtcttta acggtttgtt tgagattttg gtaaatttga
    20881 ctttctccta tctcccgctt tggcgcctct ttattgactg tcatcacacc atcttttatc
    20941 gtcacaaagc ctagttcttc aaatacttga atcatcttga ccagcaagat ttgttgaata
    21001 ttaagatatg cagccaaatc tttcagcttg tagcgaatat caaactctgg gaactggtaa
    21061 atagtcttgt acaatttagc aaactgatct ctagtcccat aacctgtcag ataataggtc
    21121 ttgtcaatat catttttgaa atagacagca gagaaatgct gttcctgaaa aatggtcttc
    21181 agctgagtaa tatcctctgg aatgtttttt acgacaacag cttcactagc cgcaagattt
    21241 ggcagttctc caggaaaatc caagactgga acaccttctg gcaagactgc attttttcca
    21301 cgaatgttaa aaagttgaac accttccact cgcgcatcca ccatcatcaa ctggagggca
    21361 gtttggccat tccattggtt gacagacaat ttaaccgcta actctagatt cttggtttga
    21421 gaaaactctg tcgcccatct gccttgacca aaggctacca cttcaaaact cgcctcaccc
    21481 ttggaaattt tcagctttag atgggcatta cctgccccca tagtacgagc actttcgacc
    21541 tgaaaattct tgatataaaa aataggtttc tgattatcca ttccaaaagg agctaaacgt
    21601 tcaaaacttt tgaccgtttc caagctaagt gcctccaaat ccaactcttc atctaggttt
    21661 aacttattct tgccaccagc atctgcacct ttttcacgaa cataatcttc caaaacctga
    21721 gataaatctg agagttgctc aacttccagc gtcatacccg ctgcacctgc atgacctcca
    21781 aaggcgatga agaggtctcg atggggatcc agagcttcaa aaatatcgac cgcttccaca
    21841 ctacgagcac tgcccttggc acgaccgtct tctatattaa gaacaatgac tgtctgtccc
    21901 aattcttcca ataaacgacc agccacgatt cctagaaccc caggattcca gccttccttg
    21961 gccaagacct gaaccttctt ctcaggatcc accatggtct tggcttcttc atagatagac
    22021 tgaacgattt ccttgcgctc ttcgtttttc tggtgaatca taagggcaat ctcatgcgct
    22081 tcctcatcat caaatccagt caacaaatca atggcaggat tgggatcatc caagcgaccc
    22141 aaggcattca aacgaggagc aatctggaaa ccaaccgttt cttctgttac ttcgttggca
    22201 gcaatcccag ccatgtccag catttcttgc agaccaatgc gctgggtatg acccaacatt
    22261 tccagaccat attgaactaa gatacgattt tcatccgtca gactcaccat atctgcaata
    22321 gttccaatag cgaccaaatc aagcaattcc acttgcactt cttctaacag ggcacaagcc
    22381 aacttgaaag caactccaca accagccaaa tatttaaaag gataatccgc atctggatgt
    22441 tcaggatgga caatagcata agcatctggc agggtttcag gcatggaatg atggtctgtc
    22501 acaatgacat ctactcccat agactgagcc aatgcaatag cctcatgacc agcaacccca
    22561 ttgtccaccg tcacaatcaa ggaaattcct tcttgctcga taaagtattt ataaacacta
    22621 gcattagggc catagccatc ggtaaaacga tttggcaggt aaactcggca ctcagcacca
    22681 agttgttcca aactttcctt cacaatagaa gccgaagtca tgccatccgc atcatagtct
    22741 ccataaacga gaatattttc cccttcttca atagcctgac gaatccgctc cactgccttg
    22801 tccatatcat ggagcagata agcatcatgt aagtcctcca aggaaggttc taaaaacttc
    22861 ttcagacttt cttggtcctg aatccctctc tcaaacaata accgagccac ctcaggaccc
    22921 agtccagcct tcttggctat ctttgtaaaa tccgcatctt ctacctgcag ggcaaactgc
    22981 cattcataag taggtgttat caaaaagaca tccactcttt ctaagaattc tattgcttca
    23041 ttataacatg atttagacgt tttctctatc cagattgctt ttttataaca ttttatagta
    23101 tattgaaact agaatagtac acctctactt ctaaaatatt gttagaaatc gatttgactg
    23161 tcccgatcga tttttcctgt tcttatttca ctatagtgaa ttttttcaga tatgatttga
    23221 caagaacatt cttttattgc agaatcgtgt tataaaatct aacataaagg agttctctca
    23281 tggttttagt agaatttaaa aacgtcgaaa aatattacgg agactaccac gcactccgca
    23341 acatcaatct ccgttttgaa aaaggacaag ttgttgtcct gcttggacct tctggctctg
    23401 ggaagtccac tcttatccgt acgatcaatg gtttagaggc tgttgacaaa ggaagtctcc
    23461 tagtcaatgg gcaccaagtt gctggtgcca gccagaaaga tttggtacct cttcgcaagg
    23521 aagtcggcat ggtttttcaa cattttaacc tttatccaca caaaacagtg ttagaaaacg
    23581 tgacacttgc gcccattaaa gttctaggaa ttgataaaaa agaagctgaa aaaaccgcca
    23641 aaaaatatct ggaatttgta aatatgtggg acaagaaaga ttcctatccc gccatgctat
    23701 ctggtggaca aaaacagcgg atcgccatcg ctcgtggtct tgctatgcat ccggaactcc
    23761 tcctctttga tgaaccaaca tctgctcttg atcctgagac tatcggagat gttctagcag
    23821 ttatgcagaa actggcgcgt gataggatga acatgatcat cgttacccac gaaatgggct
    23881 ttgctcgaga ggttgcggac cgcattatct ttatggccga cggagaagtt ttagtagata
    23941 cgacagatgt cgataacttt tttgacaatc caagcgaacc tcgtgcccaa caattcctca
    24001 gcaaaattat caaccacgaa agtgacaaag tcaaataagg aggcgcctat gaaaaaaaat
    24061 tctttttatc agcattattg attagccttt tcggccttgc tgctgccaaa ccagtccagg
    24121 ctgatacaag tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt gtcaaacaag
    24181 acgttcccaa ttttggttac aaagatccca agaccggtac ttattctggt atcgaaaccg
    24241 acttggccaa gatggtagct gatgaactca aggtcaagat tcgctatgtg ccggttacag
    24301 cacaaacccg cggccccctt ctagacaatg aacaggtcga tatggatatc gcgaccttta
    24361 ccatcacgga cgaacgcaaa aaactctaca actttaccag tccctactac acagacgctt
    24421 ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta aacggcaaaa
    24481 ccatcggagt cgcccaaggt tctatcaccc aacgcctaat tactgaactg ggtaaaaaga
    24541 aaggtctgaa gtttaaattc gtcgaacttg gttcctaccc agaattgatt acttccctgc
    24601 acgctcatcg tatcgatgcc ttttccgttg accgctctat tctatctggc tacactaata
    24661 aacggacagc actactagat gatagtttca agccatctga ctacggtatt gttaccaaga
    24721 aatcaaatac agagctcaac gactatcttg ataacttggt tactaaatgg agcaaggatg
    24781 gtagtttgca gaaactttat gaccgttaca agctcaaacc atctagtcat accgcagatt
    24841 aaggaggata ccctatgaca gatttatcat cttggacagc ctattttcag gattttggac
    24901 aatttttcaa tggtttcctc tttactcttg ccctagcgat tggatccttt atcctcgcca
    24961 tggtcttagg aatcttcttt ggtgccatgt caaccagtaa acgtccaatt ttacgcattt
    25021 tagctcgcat ctttgtggaa ttttaccaaa atactcctct cttggtgcag tttgttattg
    25081 ttttttatgg cctacctctt atcagtgacc atatcatcat gattccaatt tattggacag
    25141 ccgttctctg cgtgggactc tatcacggcg cttatatcgc tgaggttatt cgttcaggga
    25201 ttcagtctat tcctagtggt cagatggagg ccgccttgtc gcaaggtttt acctatatca
    25261 gtgccatgcg cttgattacc ttgcctcaga ccttccgcat cattctccct ccattgacca
    25321 accaaattgt taacctcatc aagaacacct ctactgtagc tatcatctct ggagtagact
    25381 tgatgtttgt gactaagtct tggtcggctc tcaacggaaa ctatatccca gcctttttag
    25441 gtgctactct tctctacttt gccctatgct tccctgttgc ccagtttggt cgcaagatgg
    25501 agcaagccaa caaaaaagcc tattcacttt aggaggttac tatggaatct attttagaag
    25561 ttttaacccc agataaccta gtctttatct ttaaaggatt tggcttgacc ctctatattt
    25621 ctctgattgc catcatcctc tctactatca tcggtacggt gctagctgtc atgagaaatg
    25681 gcaaaaatcc tgtcttgcga atcatctcca gcatttatat cgaatttgtg cgcaacgttc
    25741 ccaaccttct ctggattttt actatctttt tggtgttcaa aatgaaatcc acaccagcag
    25801 gtattacagc ctttactctc tttacatcag cagccttggc tgagattatt cgaggcggtc
    25861 tcaatgccgt agacaaggga caatacgaag caggaatgtc acaaggcttc acctcagccc
    25921 aaatcctcta ctacatcatt ctcccacaag ccatccgcaa aatgctacca gccatcattt
    25981 ctcagtttgt taccgtgatt aaggatacca gcctcctcta ctctgttatc gccctacaag
    26041 aactctttgg agccagccaa attctcatgg gccgttattt cgaaccagag caggtcttca
    26101 gtctttgcat cctgattgcc ctcatctact tcagctttaa cctagcaatt tctagcctgt
    26161 ctcatatgct agccaaacgt tggcaacaag ctgcagaata atactcttcg aaaatctctt
    26221 caaaccacgt tagctctatc tgcaacctca aaacagtgtt ttgagcaact tgcggctagc
    26281 ttcctagttt gctctttgat tttcattgag tataaacagc cactctccag ttcaattgga
    26341 gagttttttg atgagagtag atatttatag acctcaattt gacaccatac attttctatg
    26401 ataaaatgta acaaatttat ttacaacaaa tcgaaatcta aatgaaatgg aattttctat
    26461 gaaatcagtc aaaggactac tctttatcat agctagtttt atcttgactc ttttgacttg
    26521 gatgaacact tctccccaat tcatgattcc aggactagct ttaacaagcc tatctctgac
    26581 ttttatccta gccactcgtc tcccactact agaaagctgg tttcacagtt tggagaaggt
    26641 ctacaccgtc cacaaattca cagcctttct ctcaatcatc ctactaatct ttcataactt
    26701 tagtatgggc ggtttgtggg gctctcgctt agctgctcaa tttggcaatc ttgccatcta
    26761 tatctttgcc agcatcatcc ttgtcgccta tttaggcaaa tacatccaat acgaagcttg
    26821 gcgatggatt caccgcctgg tttacctagc ctatatttta ggactctttc acatctacat
    26881 gataatgggc aatcgtctcc ttacatttaa tcttctaagt tttcttgtta gtagctatgc
    26941 ccttttaggc ttactagctg gtttttatat catttttcta tatcaaaaga tttccttccc
    27001 ctatctaggg aaaattaccc atctcaaacg cttaaatcac gatactagag aaattcaaat
    27061 ccatcttagc agacctttca actatcaatc aggacaattt gcctttctaa agattttcca
    27121 agaaggcttt gaaagtgctc cgcatccctt ttctatctca ggaggtcatg gtcaaactct
    27181 ttactttact gttaaaaatt caggcgacca taccaagaat atctatgata atcttcaagc
    27241 cggcagcaaa gtaaccctag acagagctta cggacacatg atcatagaag aaggacgaga
    27301 aaatcaggtt tggattgctg gaggtattgg gatcaccccc ttcatctctt acatccgtga
    27361 acatcctatt ttagataaac aggttcactt ctactatagc ttccgtggag atgaaaatgc
    27421 agtctaccta gatttactcc gtaactatgc tcagaaaaat cctaattttg aactccatct
    27481 aatcgacagt acaaaagacg gctatcttaa ttttgaacaa aaagaagtgc ccgaacatgc
    27541 aaccgtctat atgtgtggtc ctatttctat gatgaaggca cttgccaaac agattaagaa
    27601 acaaaatcca aaaacagagc ttatttacga aggattcaag ttcaaataag taatcatact
    27661 ctcctgggat ttcccaggag agttttttat agccaaatga aataagacag gaacgatgga
    27721 attttggcat tcaaatcaat tgataagaat gttttatagt ggagtgaaat aggatacgaa
    27781 caaattgatt aggaaaatca aatgaattta tagaaatctt ttagcagtta tgttgtccta
    27841 ttctagtttc aaaacgctat agaagcagca ttgtgctagt ctagattcag tttactatac
    27901 taaaacgagt agcttgaaat caaaaaaccc accctcacag gcaggtttta tctgtattat
    27961 tcagctagat tatgctttac cttctgaacc gaatacgtcg atacgttctt caaccgatgc
    28021 ttggatagct tttacaccgt cagccaagaa tttacgtggg tcgaagagtt ttttcttgtc
    28081 gtattctgct tcgtttgctt cgtagtcacg agcaaattta cgagttgcgt tagcgaatgc
    28141 gatttggcat tctgtgttaa cgttaacttt ggcaacacca agtttgatag ctgcttggat
    28201 ttgctcatca ggaatacctg atccaccgtg caatacgatt gggaatcctg gaagagcttc
    28261 tgtcaatttt tgcaagtggt caaggtctag accttcccag tttactgggt aagggccgtg
    28321 gatgttaccg ataccagctg ccaagaagtc gataccagtt tcaaccattg ctttagcgtc
    28381 ttcgattgga gccaattcac ctttaccgat gattccgtct tcttcaccac cgatagtacc
    28441 aacttcagct tctactgaga tacctttagc gtgtgctttt tcaacaactt ctttagccaa
    28501 tttaaggttt tcttcaactg gaaggtgtga accgtcaaac atgattgaag tataaccaac
    28561 ttcgatacac tcaagtgcat cttcgtagtg accgtggtca aggtggatag ctactggtac
    28621 agtgataccc attgattcaa caaggttagc gatcaagttg cgagcaactt tgtaaccacc
    28681 catgtattta gcagcaccca ttgaagtttg gatcaaaact ggagcttttt tagcttctgc
    28741 tgcgcgcaag atagcttgag tccactcaag gttgtttgtg ttaaatccac caactgcata
    28801 accgttgtca cgggctgctt ggacaaattt ttctgctgaa acgattgcca ttttatcagg
    28861 cctcctgtat atttttatgg gtcatcccat ttacattgtt cattttatca ctttttgcca
    28921 aaaaaatcta gtttttcccg cagtttcgat tgattttctt ctaactccat ctatgtaaac
    28981 cctttctccc tagtcttgga cgacttttgg aaaatctata aagaaggtta aacgattctc
    29041 ctccatctcg aaacgataag ctaatttttc atgttctaat agactcttaa ccacaaagag
    29101 ccccatacca gaccccttga ccttgcgact agcattgtca gaaaaagact gggctagttt
    29161 ttcttgttcc tctgagctac agctattttc gataaaaagt tctccttctc tttctccaat
    29221 tcgaactaag ccacctggaa cagagtgctt aatggcattg ctgatgagat tagaaagaat
    29281 caacttcata actgatgggt ttagataagc ctgctgatgg gtcaaactat tgtctatctg
    29341 gagctctctt tcctttgcta gcaaggcata atctttgacc agattttgcg tcatctggag
    29401 gaggtcaatt gtttccctat catctcgcaa ttcctgcaca gaagagaggg aaagtatctg
    29461 cagaacatgg tgattgagtt catccacaat ccccaaggca actcccagat actggtctct
    29521 atccttataa cgaccgatat tctctctcat attttcgatt aggattttca aactagccag
    29581 cggtgttttc aattcatgag aagctcctcg taggaattcg accttcatct tctccagctg
    29641 gagaatggct tcattctttt catgcaagtc cgcaataaca gtcaagagat gctggtagag
    29701 gctattgatt tgttccttga gattacctat ctcatcctta gaatccacgc gcaatcgcac
    29761 ttgggaatcc aggtccatca tccgacgggt cacccgcttg atttccaaaa tcggtgcaac
    29821 aatagtccga gcgtagatgt aggccaccaa gagggaaatc agaaaggagg ccagcaaggt
    29881 atagggaaga aactggagac tgatttgctc cgcttccttt tgtaaatcca tggaagctag
    29941 aaactggaga atcatagtac caccgtcttg cgttttcacc tcgcgctcct caataaagag
    30001 agaggttgtc tggcggtctg tgtccagagg aagactgtcc ttgacttcta acttgtcctc
    30061 ggtcatctca cctttgacgg tccccttgat atcactagtc tgggaataca agtctaacac
    30121 ttgctcgata ctctgcctat ctttcccttc tagggactgg gcaatggctg ttgccttttg
    30181 accaatggtt tcctgacgat gactcagata agtcgaagga aaaagaaaat aaatagctaa
    30241 atgaaggcag ataaccagaa cactaaatat cgagaaggta tagataaata tctttgcaaa
    30301 taaacctgtt cgtttcattt tcgctccaat ttataaccaa cattgcgcac agtgaggata
    30361 caatccaagt ctagcttttt ccgcaattcc ttgatataaa catcaataac acggtcaaag
    30421 ggaacctcat ctgtcgcttt ccagacggca tcgataatct gagatcgagt caaggcccgg
    30481 ccttcatttt tcactagata gtccagaatt tccaactctt tggcattgat aggcacttct
    30541 tgacctgcga ggcttgcact gtagctttca aagtccacct tggtatcctt gtaagaaaag
    30601 attcgtcctg tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt taaaagggag
    30661 agggagaaag gtttttccag atagccatct gccaaagagg caaaggcact catcttgtat
    30721 tcctcatctt gaaaagctgt caacatcaag acaggaacct gactggtttt acgaatctca
    30781 gctaggactt ctaagccgtt gagcttgggc atctggatat ccagtaaaac cagggccacc
    30841 tcatagctag aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat agtttcatag
    30901 ccacaatccg tcaaataatc actgaccccc tcacggatca tctcttcatc ttctacaatt
    30961 aaaattttca tactttaact gctctctatt ttttattttt cttagaataa atacctaccc
    31021 tattttctat tatagtctct tgctggcctt ttgtctgcaa gcaactgacc actagataaa
    31081 acgttgtgaa attcctttct cataaattcc ataactttag tatattatat ttaagcacta
    31141 aagtacaaag aaagcaactg aaagcaatga ttttcaccac tgctttcgga tttattttga
    31201 attgttaaat agccattcct atccactatt cttgaataga aacacaagat gcaatcttta
    31261 ttctagactc attttttcaa atttattcac catccagcaa gagctctttt ggttgttttc
    31321 taaggagatt gcttgaagca agcgccataa cgagaaccac tagaaccaag gcaaggacaa
    31381 aaatgatgat aaagtctgat gtctgaatgg aaatgtctag gctcgacaag gtcttgctaa
    31441 agccatctac ttctgcacca ccaccaaggt tagaggcttg agccgcctta ctagcctgtt
    31501 tggcaacacc tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg gcagtgtaat
    31561 tagctaggaa gtaagcagaa actagagcag ggatagcaat caagatagat tcggtgatga
    31621 attgacccaa gatacttgcc tgcttgaggc cgatagagag gagaattccc acttccttgc
    31681 gacgggcgtt gatccaaagg ctgagcaaga gggcaaggag gagaactgag aagctcaagc
    31741 taccccagaa gaggaggttg gccatcttgt acataccaga gatagattgc tcaagagctg
    31801 ggtagttaga ggagctcttg acgagtgtgt agctcttcca gttgatacca ctgatgccat
    31861 tcaactcttt cataacatca tccaagttct tgtctgctgt tacaaagaag gttgcgtccc
    31921 cataaatggc tgtgtcttct gtgtatccat aaagttttgc agcagtgtga atgtctgtaa
    31981 tagctgtgtt ttcgtaaagt tcttgtgagt aggttactgc tgacttatta tgaccatcaa
    32041 agagtccctt gattgtcact tcaactgttt ccttggctcc tttttcatta tctgcatcgt
    32101 agatattaga gtccagttta accttgtccc ctactttcca gccgtgtttg gctgccaagt
    32161 ccttgtgcaa gaggatttta tccttgtcgt cgttggttaa gtgctctcct tcgactagtt
    32221 tataagaacc agagacaaac ttgtcttctt tagaggagtc attgacacct gtaatcatca
    32281 agctacttcc aaaacgcttg gcacgatcag cagtgagatt cttcttggtt tctggcgttt
    32341 caatcaggtc atatccagtc aaatctccga tagcgttgat acgtttgaca taagactcaa
    32401 tggccttgtt ttcggtgatt tttttgatgt cttcaccctt gatattccca gcaccacgag
    32461 gcgttccttg gttgacgcga cgattgattt gcatggagaa gctattggtg atatttttaa
    32521 aggtctcctg agaagccttg gcagtagctc ccttgattga caagccgacc aaactcaagc
    32581 tcgccatgag gagaataatc aggaagatga caatcgattt gaaaaacttc cttgtaacat
    32641 aggcaaatgc gttgtgtaac atagattccc tttctagatt ttgttttaat cattctatta
    32701 aaataagctc aaattattta ctagtattgc gcgtttcagt cagtttctta tcctttaatt
    32761 caagtgtaat atctgacgct tgtgccactt ctttactgtg agttacgaca atcacacatt
    32821 tacctgtttt ctgggcaagt gatttgagta gttcgacaat atctccagca gttttaggat
    32881 ccagatttcc tgttggctca tcagctagaa taactggagc ttctgagacc aaactgcgag
    32941 caatggcaac acgttgctgt tgaccacctg ataactggag aacattccgc ttgatctggc
    33001 tttcatccaa accaagctca agaagtgtat tcttgcttgc ctttttgttg accaatcgga
    33061 tattttccag cggagaaaga taatctatca agttataatt ttgaaagacc agggaaatat
    33121 ggtgcatgcg atggtaagaa tagcccttct tacgaatatc ctctccttga aaaaggatag
    33181 aaccttcaac aggactatct agaccagcaa gtagggacaa gagtgtggat tttcctgctc
    33241 ctgactcccc aataatactg taaaattttc cgggttcaaa attataattg atctgatata
    33301 ggactgcttc agcagtattc ttataacggt aggtaacatc ttgtaattgt aataaagtca
    33361 tgatttctcc ttcttaacta atagatgata aaatttcttt cggtgatttt ctaaataaga
    33421 ataggaaaca aagggctaca gataagcaac taagcagaac tagaaaaaca taggattctg
    33481 caaaagataa gatgctagtt gataaactgc ttgctttggc tagtgtatct tgtaagcttg
    33541 cctgatctcc acttgctagt agagtttgga gtaggtaagt tgtgattgcg tttcctgcaa
    33601 caaatgctgg aagcaaagct ccaagagata ccaaaactac ctctaaacag aattgtagga
    33661 agatcgagct cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag acccgttctc
    33721 tcaaccagag agacaaaacc agaattaagg ctccagctcc tgctatcaac atcccataaa
    33781 ggaagatggt caggaaggtt tggaaagttg caactgagtc tttgatttgt tcaaaagcct
    33841 tgttttcctt ttcgacttgg tagccttgat tttccaaggc caagttttct acctgcttca
    33901 tgagtccgtc catttcctta ggattttcta catagaagcg tgctgcactg acttgagctt
    33961 cactattgcc caaaagggtt tggctacttt catagtctgt aaagacttga ttttcactga
    34021 agtcagaaga caagcctgtg aatttctctt gttttttacc agaaaagatg ccgataatct
    34081 caaactctac tgtttgtcct tttccagatt cagactgacc agcatccaag ccaatcttgt
    34141 catgaagcga aagaccgttc ttcttagcca attcttcgtg gataaggatt ttcttggaat
    34201 cccctttttg aaggtgtcgc ccttctttta gattgaaagc cgaactggta aaggttacat
    34261 ccttggatga atcctcaaga gccgttaagc taaccaagtt attgtctgca gctgataaat
    34321 catcacgctc cacgctctgc tcgccagtca ctgcttcctt gtcttttagt tttgcgaccg
    34381 tctcaagttc aggagagaca ttttccagcc ccttaatctt gcttacagat gctaggtctg
    34441 acaacttgaa tgtctgacca ttctctatct tcttaataga aaaagatgta ttgagtgatt
    34501 tataaagatt gctttctact gttttgttgg acttcatcag agtcaaacag gctgaaattc
    34561 cggccaataa gaccaataaa atcagaaata aaataaaact tctcagtcgc tttctgctga
    34621 cataagccca agatctttgg attggattca tttgtcacct ccatatttgt aagactatta
    34681 taaaacccaa atatgaaatg tttatgaaat acgaaaaaaa aatatcgagt aggggataat
    34741 ctctagcccc tctcacacca cc
//
LOCUS       DAVLZG010000016        34591 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLZG010000016 DAVLZG010000000
VERSION     DAVLZG010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.016"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            609..1061
                     /locus_tag="VYO72_000738"
                     /pseudo
     CDS             609..1061
                     /locus_tag="VYO72_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            1080..2417
                     /locus_tag="VYO72_000739"
     CDS             1080..2417
                     /locus_tag="VYO72_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1707145.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2496..3380
                     /locus_tag="VYO72_000740"
     CDS             2496..3380
                     /locus_tag="VYO72_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1707146.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3380..4213
                     /locus_tag="VYO72_000741"
     CDS             3380..4213
                     /locus_tag="VYO72_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1707147.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLITIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4232..6325
                     /gene="nanB"
                     /locus_tag="VYO72_000742"
     CDS             4232..6325
                     /gene="nanB"
                     /locus_tag="VYO72_000742"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1707148.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6338..7441
                     /locus_tag="VYO72_000743"
     CDS             6338..7441
                     /locus_tag="VYO72_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1707149.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7615..8313
                     /locus_tag="VYO72_000744"
     CDS             7615..8313
                     /locus_tag="VYO72_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1707150.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8332..9849
                     /locus_tag="VYO72_000745"
     CDS             8332..9849
                     /locus_tag="VYO72_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1707151.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9974..11302
                     /locus_tag="VYO72_000746"
     CDS             9974..11302
                     /locus_tag="VYO72_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707152.1"
                     /translation="MKFRKLACTVLAGAVVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11554..12420
                     /locus_tag="VYO72_000747"
     CDS             11554..12420
                     /locus_tag="VYO72_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1707153.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12436..13275
                     /locus_tag="VYO72_000748"
     CDS             12436..13275
                     /locus_tag="VYO72_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1707154.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13548..14000
                     /locus_tag="VYO72_000749"
     CDS             13548..14000
                     /locus_tag="VYO72_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1707155.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14133..14441
                     /locus_tag="VYO72_000750"
     CDS             14133..14441
                     /locus_tag="VYO72_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707156.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGAYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFAYNIAAAWDAHDKIPNNGRINF
                     "
     gene            14725..15369
                     /locus_tag="VYO72_000751"
     CDS             14725..15369
                     /locus_tag="VYO72_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1707157.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15538..16455
                     /locus_tag="VYO72_000752"
     CDS             15538..16455
                     /locus_tag="VYO72_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1707158.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16473..17357
                     /locus_tag="VYO72_000753"
     CDS             16473..17357
                     /locus_tag="VYO72_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1707159.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGLVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17373..18224)
                     /locus_tag="VYO72_000754"
     CDS             complement(17373..18224)
                     /locus_tag="VYO72_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1707160.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18424..20481
                     /gene="pbp2b"
                     /locus_tag="VYO72_000755"
     CDS             18424..20481
                     /gene="pbp2b"
                     /locus_tag="VYO72_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1707161.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20492..21088
                     /gene="recR"
                     /locus_tag="VYO72_000756"
     CDS             20492..21088
                     /gene="recR"
                     /locus_tag="VYO72_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1707162.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21264..22307
                     /locus_tag="VYO72_000757"
     CDS             21264..22307
                     /locus_tag="VYO72_000757"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1707163.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22391..23764
                     /locus_tag="VYO72_000758"
     CDS             22391..23764
                     /locus_tag="VYO72_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1707164.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23751..24362
                     /locus_tag="VYO72_000759"
     CDS             23751..24362
                     /locus_tag="VYO72_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1707165.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGQREQYLD"
     gene            24453..25157
                     /locus_tag="VYO72_000760"
     CDS             24453..25157
                     /locus_tag="VYO72_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1707166.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25376..26749
                     /gene="ftsA"
                     /locus_tag="VYO72_000761"
     CDS             25376..26749
                     /gene="ftsA"
                     /locus_tag="VYO72_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1707167.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26766..28025
                     /gene="ftsZ"
                     /locus_tag="VYO72_000762"
     CDS             26766..28025
                     /gene="ftsZ"
                     /locus_tag="VYO72_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1707168.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28030..28701
                     /locus_tag="VYO72_000763"
     CDS             28030..28701
                     /locus_tag="VYO72_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1707169.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28711..29250
                     /locus_tag="VYO72_000764"
     CDS             28711..29250
                     /locus_tag="VYO72_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1707170.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29250..29513
                     /locus_tag="VYO72_000765"
     CDS             29250..29513
                     /locus_tag="VYO72_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1707171.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29570..30295
                     /locus_tag="VYO72_000766"
     CDS             29570..30295
                     /locus_tag="VYO72_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1707172.1"
                     /translation="MEWIKKVEDSYAPFLTPFINPHQEKLLKILAKTYGLACSSSGEF
                     VSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHLTHAKILGTVINQLGIERKLF
                     GDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEERPFTEKIDKLEQYRELDLSV
                     SSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDKSDYTVQVGDLISVRKFGRLR
                     LLQDKGQTKKEKKKITVQLLLSK"
     gene            30304..31092
                     /gene="divIVA"
                     /locus_tag="VYO72_000767"
     CDS             30304..31092
                     /gene="divIVA"
                     /locus_tag="VYO72_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1707173.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31440..34232
                     /locus_tag="VYO72_000768"
     CDS             31440..34232
                     /locus_tag="VYO72_000768"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1707174.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKIIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
BASE COUNT        10670 a         6106 c         7519 g        10296 t
ORIGIN      
        1 aaagacttga aatgctaaaa aaaaaaagta tactctaatt gaaaacggta acaaaactaa
       61 tttagagaat gaaatataga gtatttctct cttaaaagtt tttggtgaaa cgagatgtag
      121 aaaggagatt tagccaaaga gtctattagt gctagaataa tagattagaa ttattttaga
      181 aaaacgaagt gagcagctta taaattcaag tccccaaata gattcatact agtatctttt
      241 gcaaaaaata aagggcgact tccttcatga atatcaattt catctataag gaaggtagct
      301 aattgaacta acttatttat tctgtttgtc gctagaaaaa tcagacctcc ttgtgaagat
      361 tgaggagata cttaatgaaa atcaaagaag aaactagcaa gctagtagca gattgcccaa
      421 aacaccgctt tgaggttgta gataagactg acgtatataa tccaaggtga agcgactgtg
      481 gtttgaagag attttcaaag agtataggct agagagtagt gtttttatgt ccttctagta
      541 gaaaatgcta gacagaagaa tggggaactt ggataggaaa aatagattga gaaaggaggt
      601 tagaagagat gattattaca aaaattagcc gtttaggaac ttatgtggga gtaaatccac
      661 attttgcaac attaatagat tttctagaaa aaacaggact agaaaattta acagaaggtt
      721 cgattgttat cgatggtaat cgattgtttg ggaattgatt tacttatcta gcagatggtc
      781 aagcaggggc tttctttgaa acacaccaaa aatatttgga tattcattta gttttggaaa
      841 acgaagaagc catggctgtt acatcgccgg aaaatgtaag cgttacccaa gaatatgatg
      901 aagagaaaga tattgaatta tacacaggga aagtggaaca gttggttcat ttgagagctg
      961 gcgaatgcct catcactttt ccagaagatt tacatcaacc caaggttcgt ataaatgatg
     1021 aacctgtgaa aaaagttgtc tttaaagttg cgatttctta atgtagaaag agaagaacga
     1081 tgaaaaaaat gagaaagttt ttatgtctag ctggaattgc gctagcggct gttgccttgg
     1141 tagcttgttc aggaaaaaaa gaagctacaa ctagtactga accaccaaca gaattatctg
     1201 gtgagattac aatgtggcac tcctttactc aaggaccccg tttagaaagt attcaaaaat
     1261 cagcagatgc tttcatgcaa aagcatccaa aaacgaaaat caagattgaa acattttctt
     1321 ggaatgactt ctatactaaa tggactacag gtttagcaaa tggaaatgtg ccagatatca
     1381 gtacagctct tcctaaccaa gtaatggaaa tggtcaactc agatgctttg gttccgctaa
     1441 atgattctat caagcgtatt ggacaagata aatttaacga aactgcctta aatgaagcaa
     1501 aaatcggaga tgattactac tctgttcctc tttattcaca tgcacaagtc atgtgggtta
     1561 gaacagattt gttaaaagaa cataatattg aggttcctaa aacttgggat caactctatg
     1621 aagcttctaa aaaattgaaa gaagctggag tttatggctt gtctgttccg tttggaacaa
     1681 atgacttaat ggcaacacgt ttcttgaact tctacgtacg tagtggtgga ggaagcctct
     1741 taacaaaaga tcttaaagca gacttgacaa gccaacttgc tcaagatggt attaaatact
     1801 gggttaaatt gtataaagaa atctcacctc aagattcttt gaactttaat gtccttcaac
     1861 aagctacctt gttctatcaa ggaaaaacag catttgactt taactctggc ttccatatcg
     1921 gaggaattaa tgccaacagt cctcaattga ttgattcgat tgatgcttat cctattccaa
     1981 aaatcaaaga gtctgataaa gaccaaggaa ttgaaacctc aaacattcca atggttgttt
     2041 ggaaaaattc aaaacatcca gaagttgcta aagcattctt agaagcactt tataatgaag
     2101 aagactacgt taaattcctt gattcaactc cagtaggtat gttgccaact attaagggga
     2161 ttagcgattc tgcagcctat aaagaaaatg aaactcgtaa gaagtttaaa catgctgaag
     2221 aagtaattac tgaagctgtt aaaaaaggta ctgctattgg ttatgaaaat ggaccaagtg
     2281 tacaagctgg tatgttgact aaccaacaca ttattgaaca aatgttccaa gatatcatta
     2341 caaatggaac agatcctatg aaagcagcaa aagaagcaga aaaacaatta aacgatttat
     2401 ttgaggctgt tcagtagatg taaaagacta gaaaataggt gggctagtga gctgaaaagc
     2461 tctagcccaa tcttgtaaaa gaagggagaa ggagaatggt taaagaacgt aatttaactc
     2521 gctggatatt tgttttgcca gctatgatta tcgtaggatt actctttgtt tatccgtttt
     2581 tctcgagtat tttttatagc tttaccaata agcatttgat tatgcctaat tataaatttg
     2641 ttggtttggc taactataaa gctgtgctat cagatcccaa cttctttaat gcgttcttta
     2701 attcaattaa gtggaccgtt ttctcattag ttggtcaagt tttagtaggg tttgtattgg
     2761 ctttagctct tcacagagta cgccacttca agaaattata taggacctta ttgattgttc
     2821 cttgggcatt tcctaccatc gttattgcct tttcttggca gtggattcta aacggggttt
     2881 atggctactt acctaatcta atcgtaaaat taggtttaat ggaacataca cctgcatttt
     2941 tgacagatag tacatgggca ttcctatgtt tggtgtttat caacatttgg tttggagcac
     3001 caatgattat ggttaatgtg ctttcagctt tgcaaacagt accagaagaa caatttgagg
     3061 ctgctaagat agatggtgct tcaagttggc aggtgttcaa gtttatcgtc tttccacata
     3121 ttaaagtggt tgtaggactt ctagttgttt tgagaactgt atggatcttt aataactttg
     3181 acattatcta cctcattact ggtggtggac cagccaatgc tacaacgacg cttccaattt
     3241 ttgcttacaa cctgggttgg ggaactaaat tgttgggtcg tgcttcagca gttacagtat
     3301 tgctctttat cttcttggtg gcgatttgct ttatctactt tgctatcatc agtaagtggg
     3361 aaaaggaggg tagaaaataa tgaagaagaa atccagtatt tatttagata ttctctcaca
     3421 tgtactttta gttggtgcga ccatcgttgc aattttccca ttggtatgga ttatcatatc
     3481 ttctgtcaaa gggaaagggg aattaactca gtatccaaca cgattttggc ctgaacagtt
     3541 tacattagat tatttcactc atgttatcaa cgatttgcac ttcattgata acattcgaaa
     3601 cagtttaatc attgccttgg ctacaaccct cattacgatt attatttctg ctatggcagc
     3661 ctatggtatt gttcgattct ttcctaaatt gggagcaatc atgtcgagac tactcgtcat
     3721 tacctatatt ttcccaccaa ttttgttagc aattccctat tcaattgcca ttgctaaagt
     3781 tgggttaaca aatagtttat ttggcttgat gatggtttat ctatctttta gtgttccata
     3841 tgcagtttgg ctcttagttg gatttttcca aacagttcca attggaattg aagaagcggc
     3901 tagaattgat ggtgcaaata aatttgttac gttttataaa gttgtgctac cgattgtagc
     3961 accaggtatt gtagcaacag ctatttatac atttatcaat gcttggaatg aattcctgta
     4021 tgccttgatt ttgattaaca atacaggaaa gatgacagta gcagtagccc ttcgttcact
     4081 taatggttca gaaatactag actggggaga tatgatggca gcgtctgtta ttgtagttct
     4141 tccatcaatt attttcttct ctatcatcca aaataagatt gcaagtggat tatcagaagg
     4201 atctgtgaag tagacgaaag aaggaaaaaa aatgaataaa agaggtcttt attcaaaact
     4261 aggaatttct gttgtaggca ttagtctttt aatgggagtt cctactttga ttcatgcgaa
     4321 tgaattaaac tatggtcaac tgtccatatc tcctattttt caaggaggtt catatcaact
     4381 gaacaataag agtatagata tcagctcttt gttattagat aaattgtctg gagagagtca
     4441 gacagtagta atgaaattta aagcagatga accaaactct cttcaagctt tgtttggcct
     4501 atctaatagt aaagcaggct ttaaaaataa ttacttttca attttcatga gagattctgg
     4561 tgagataggt gtagaaataa gagacgccca aaagggaata aattatttat tttctagacc
     4621 agcttcatta tggggaaagc ataaaggaca ggcagttgaa aatacactag tatttgtatc
     4681 tgattctaaa gataaaacat acacaatgta tgttaatgga atagaagtgt tctctgaaac
     4741 agttgataca tttttgccaa tttcaaatat aaatggtata gataaggcaa cactaggagc
     4801 tgttaatcgt gaaggtaagg aacattacct cgcaaaagga agtattgatg aaatcagtct
     4861 atttaacaaa gcaattagtg atcaggaagt ttcaaatatt cccttgtcaa atccatttca
     4921 gttaattttc caatcaggag attctactca agctaactat tttagaatac cgacactata
     4981 tacattaagt agtggaagag ttctatcaag tattgatgca cgttatggtg ggactcatga
     5041 ttctaaaagt aagattaata ttgccacttc ttatagtgat gataatggga aaacgtggag
     5101 tgagccaatt tttgctatga agtttaatga ctatgaggag cagttagttt actggccacg
     5161 agataataaa ttaaagaata gtcaaattag tggaagtgct tcattcatag attcatccat
     5221 tgttgaagat aaaaaatctg ggaaaacgat attactagct gatgttatgc ctgcgggtat
     5281 tggaaataat aatgcaaata aagccgactc aggttttaaa gaaataaatg gtcattatta
     5341 tttaaaacta aagaagaatg gagataacga tttccgttat acagttagag aaaatggtgt
     5401 cgtttatgat gaaacaacta ataaacctac aaattatact ataaatgata agtatgaagt
     5461 tttggaggga ggaaagtctt taacagtcga acaatattcg gttgattttg atagtggctc
     5521 tttaagagaa aaacataatg gaaaacaggt ccctatgaat gttttctaca aagattcgtt
     5581 atttaaagtg actcctacta attatatagc aatgacaact agtcagaata gaggagagag
     5641 ttgggaacaa tttaagttgt tgcctccgtt cttaggagaa aaacataatg gaacttactt
     5701 atgtcccgga caaggtttag cattaaaatc aagtaacaga ttgatttttg caacatatac
     5761 tagtggagaa ctaacctatc tcatttctga tgatagtggt caaacatgga agaaatcctc
     5821 agcttcaatt ccgtttaaaa atgcaacagc agaagcacaa atggttgaac tgagagatgg
     5881 tgtgattaga acattcttta gaaccactac aggtaagata gcttatatga ctagtagaga
     5941 ttctggagaa acatggtcga aagtttcgta tattgatgga atccaacaaa cttcatatgg
     6001 cacacaagta tctgcaatta aatactctca attaattgat ggaaaagaag cagtcatttt
     6061 gagtacacca aattctagaa gtggccgtaa gggaggtcaa ttagttgttg gtttagtcaa
     6121 taaagaagat gatagtattg attggaaata ccactatgat attgatttgc cttcgtatgg
     6181 ttatgcctat tctgcgatta cagaattgcc aaatcatcac ataggtgtgc tgtttgaaaa
     6241 atatgattcg tggtcgagaa atgaattgca tttaagcaat gtagttcagt atatagattt
     6301 ggaaattaat gatttaacaa aataaaggag aaaaaacatg gttaaatacg gtgttgttgg
     6361 agcagggtat tttggagctg aattggctcg ctacatgcaa aagaatgatg gagcagagat
     6421 tactcttctc tatgatccag ataatgcaga ggcgattgca gaagaattgg gagcaaaagt
     6481 agcaagttcc ttagatgagt tggtttctag cgatgaagta gattgtgtta tcgtcgcaac
     6541 tccaaataat cttcataagg aaccggttat taaggctgca cagcatggta aaaatgtttt
     6601 ctgtgaaaaa ccaattgcgc tttcttatca agattgtcgc gagatggtag atgcgtgtaa
     6661 agaaaacaat gtaaccttta tggcaggaca tattatgaat ttctttaatg gtgttcatca
     6721 tgcaaaagaa ctcattaatc aaggagttat cggagacgtt ctatattgtc atacagctcg
     6781 taatggttgg gaagaacaac aaccgtcagt atcatggaaa aaaattcgtg aaaaatcagg
     6841 tggtcacttg tatcaccaca tccatgaatt ggattgcgtt caattcctta tggggggcat
     6901 gcctgaaact gtaaccatga caggtggaaa tgtggcccat gaaggtgaac atttcggtga
     6961 tgaagatgat atgatttttg tcaatatgga attttctaat aagcgttttg ccttgttaga
     7021 atggggttca gcttatcgtt ggggtgaaca ttatgtctta atccaaggaa gcaaaggtgc
     7081 catccgctta gacttattca actgtaaagg aactcttaag ctagatgggc aagaaagcta
     7141 tttcttgatt cacgaatcgc aagaagaaga tgatgatcgg actcgtatct atcatagtac
     7201 agagatggat ggagcaattg cttatggtaa accaggtaaa cgtactccat tatggctatc
     7261 atctgtcatt gataaagaaa tgcgctatct gcatgagatt atggaaggag ccccagtatc
     7321 agaagaattt gcaaaacttt tgacaggtga agctgcccta gaagcaattg ctactgcaga
     7381 tgcttgtacc cagtctatgt ttgaagatcg caaagtaaaa ttgtcagaaa ttgtaaaata
     7441 aattttggta ttctcctatt tataggtcga cttgctcctc tgaaagtact tttagaggag
     7501 ctgtttgact ttgctagttt ttgaaactga aatctattat actacaaact attgaaagcg
     7561 ttttaatttt aaggtataat aatctcatag aaataaagaa aaggaggaaa gaggatgcca
     7621 cagattagca aagaagcctt gattgagcaa atcaaagatg gaatcatcgt ttcttgtcag
     7681 gctcttcctc atgaaccgct ttatacagaa gcgggagggg tgattccctt gctggtcaaa
     7741 gcggctgagc aaggtggagc agtcggtatc cgagcaaaca gtgttcgcga tatcaaggaa
     7801 attaaggaag tcactaaact tccaatcatt gggattatca aacgtgatta tccacctcag
     7861 gaacccttca tcacggctac tatgaaagaa gttgatgaat tggcagaact ggacatcgag
     7921 gtgattgctc tggattgtac caagcgtgaa cgctacgatg gtttggaaat tcaagagttc
     7981 attcgtcagg ttaaggagaa atatcctaat cagcttttga tggctgatac tagtatcttc
     8041 gaagaagggc tagcagctgt agaagcagga attgactttg tcggaacaac cttatcaggc
     8101 tacacatcct acagtccaaa agtagacggt ccagattttg aattgattaa gaaactctgt
     8161 gatgccggtg tagatgtcat tgcagaagga aaaattcata caccagaaca agccaaacaa
     8221 atccttgaat atggagtgcg aggcatcgtt gttggtggcg ccattactag accaaaagag
     8281 attacagaac gcttcgttgc tagtcttaaa taagatgtga gagggagttt tatgtttaaa
     8341 gttttacaaa aagttggaaa agcttttatg ttacctatag ctatacttcc tgcagcaggt
     8401 ctacttttgg ggattggtgg tgcactttca aacccaacca cgatagcaac ttatccaata
     8461 ctagacaata gtatttttca atcaatattc caagtaatga gctctgcagg agaggttgta
     8521 ttcagtaatt tgtcactact tctctgtgtg ggattatgta ttggcttagc gaaacgagat
     8581 aaaggaaccg ctgcgttagc aggagtaact ggttacttag ttatgactgc aacgatcaaa
     8641 gctttggtaa aactttttat ggcagaagga tctgcaattg atactggagt tattggagca
     8701 ttagttgtcg gaatagttgc cgtatatttg cacaaccgat ataacaatat tcaattacct
     8761 tccgctttag gattctttgg aggttcacgc ttcgttccta ttgttacatc gttctcttct
     8821 atcttgattg gctttgtctt ctttgttatt tggccacctt tccaacaact tcttgtttct
     8881 acaggtggat atatttctca ggcgggtcca attggaactt ttctatatgg atttttaatg
     8941 agactttctg gagcagtagg cttacatcat ataatttacc ctatgttttg gtatactgaa
     9001 cttggtggtg ttgaaactgt tgcaggacaa acagtggttg gagctcaaaa aatatttttt
     9061 gctcaattag ccgatccggc ccattctgga ttatttacag aaggaacaag gttttttgca
     9121 ggtcgtttct caacaatgat gttcggttta ccggctgcct gtttagcgat gtaccatagt
     9181 gttcctaaaa atcgtcgtaa aaaatacgcg ggtttgtttt ttggagttgc tttaacatct
     9241 tttattaccg gtattacaga accaattgaa tttatgtttc tattcgtcag tccggttcta
     9301 tatgttgttc acgcattcct tgatggtgtt agcttcttta ttgcagacgt cttaaatatt
     9361 tcaataggaa acacattttc aggaggtgta atcgatttca ctttatttgg aattttgcag
     9421 gggaacgcta agacgaattg ggttcttcag attccaattg gacttatttg gagtgttttg
     9481 tattatatta tttttagatg gttcattact caattcaacg ttctaacgcc aggacgagga
     9541 gaagaagtag attctaaaga aatttctgaa tccgcagatt caacttcaaa tactgcagat
     9601 tatttaaaac aggatagcct acaaattatc agagccttgg gtggatcaaa taatatagaa
     9661 gatgtagatg cttgtgtgac acgtttacgt gtagctgtaa aagaagttaa tcaagttgat
     9721 aaagcacttt taaaacaaat tggtgcagtt gatgtcttag aagtgaaggg tggcattcaa
     9781 gcaatctatg gagcaaaagc aatcttatat aaaaatagta ttaatgaaat tttaggtgta
     9841 gatgattaag tacttactga cttaataaaa aacagaggag agtgatggat gagtaggatg
     9901 aaatgaaatc gtatacaaga aataaagaac tcattatcca agttggatac gcttattaca
     9961 taggagaata caaatgaaat ttagaaaatt agcttgtaca gtacttgcgg gtgctgtggt
    10021 tcttggtctt gctgcttgtg gcaattctgg cggaagtaaa gatgctgcca aatcaggtgg
    10081 tgacggtgcc aaaacagaaa tcacttggtg ggcattccca gtatttaccc aagaaaaaac
    10141 tggtgacggt gttggaactt atgaaaaatc aatcatcgaa gcgtttgaaa aagcaaaccc
    10201 agatataaaa gtgaaattgg aaaccatcga cttcaagtca ggtcctgaaa aaatcacaac
    10261 agccatcgaa gcaggaacag ctccagacgt actctttgat gcaccaggac gtatcatcca
    10321 atacggtaaa aacggtaaat tggctgagtt gaacgacctc ttcacagatg aatttgttaa
    10381 agatgtcaac aatgaaaaca tcgtacaagc aagtaaagct ggagacaagg cttatatgta
    10441 tccgattagt tctgccccat tctacatggc aatgaacaag aaaatgttag aagatgctgg
    10501 agtagcaaac cttgtaaaag aaggttggac aactgatgat tttgaaaaag tattgaaagc
    10561 acttaaagac aagggttaca caccaggttc attgttcagt tctggtcaag ggggagacca
    10621 aggaacacgt gcctttatct ctaaccttta tagcggttct gtaacagatg aaaaagttag
    10681 caaatataca actgatgatc ctaaattcgt caaaggtctt gaaaaagcaa ctagctggat
    10741 taaagacaat ttgatcaata atggttcaca atttgacggt ggggcagata tccaaaactt
    10801 tgccaacggt caaacatctt acacaatcct ttgggcacca gctcaaaatg gtatccaagc
    10861 taaactttta gaagcaagta aggtagaagt ggtagaagta ccattcccat cagacgaagg
    10921 taagccagct cttgaatacc ttgtaaacgg gtttgcagta ttcaacaata aagacgacaa
    10981 gaaagtcgct gcatctaaga aattcatcca gtttatcgca gatgacaagg agtggggacc
    11041 taaagacgta gttcgtacag gtgctttccc agtccgtact tcatttggaa aactttatga
    11101 agacaaacgc atggaaacaa tcagcggctg gactcaatac tactcaccat actacaacac
    11161 tattgatgga tttgctgaaa tgagaacact ttggttccca atgttgcaat ctgtatcaaa
    11221 tggtgacgaa aaaccagcag atgctttgaa agccttcact gaaaaagcga acgaaacaat
    11281 caaaaaagct atgaaacaat agtccttagt tattctataa aaagtagttt tttaaagaac
    11341 ctaagagtgt ataccccctt ttccctctac acagatagtg taagaaaagg gggcttttgt
    11401 ttaaaatgta agaaactgtc acgaaattaa aatgaagttc ttacataagc gaatcataaa
    11461 aaatttcatt ttgattttaa aacagttcaa gaaagtcaaa aaattattct atttgaaaga
    11521 gaggtgccga ctgtgaaagt caataaaatc cgtatgcggg aaacagtgat ttcctacgct
    11581 ttcctagcac cagtattatt cttctttgtc atctttgtgt tggctccgat ggtgatgggc
    11641 ttcattacaa gtttctttaa ctactcaatg actaaatttg agtttgtagg cttggataac
    11701 tatatccgta tgtttaaaga tcctgtcttt acaaaatctc tgattaacac agttattttg
    11761 gttattggat ctgtaccagt tgttgttcta ttctcactct ttgtagcatc tcagacctat
    11821 catcaaaatg tcattgccag atccttctac cgtttcgtct tcttccttcc tgttgtaacg
    11881 ggtagtgttg ccgtgacagt tgtttggaaa tggatttatg acccactatc agggattcta
    11941 aactttgtcc ttaagtcaag ccacatcatc agccaaaaca tttcttggtt gggagataaa
    12001 aactgggcat tgatggcgat tatgattatt ctcttgacca cttcagttgg tcagcccatc
    12061 atcctttata tcgctgccat ggggaatatt gacaattcac tggttgaagc ggcgcgtgtt
    12121 gatggtgcaa ctgagtttca agttttttgg aagattaaat ggccaagcct tcttccaaca
    12181 actctttata ttgcaatcat cacaacaatt aactcattcc agtgtttcgc cttgattcag
    12241 cttttgacat ctggtggtcc aaactactca acaagtacct tgatgtacta cctttacgaa
    12301 aaagccttcc aattgacaga atacggctat gccaacacaa ttggtgtctt cttggcagtc
    12361 atgattgcta tcgtaagctt tgttcaattt aaagtacttg gaaacgacgt agaatactaa
    12421 agaaaggaga cagctatgca atctacagaa aaaaaaccat taacagcctt tactgttatt
    12481 tcaacaatca ttttgctctt gttgactgtg ctgttcatct ttccattcta ctggattttg
    12541 acaggggcat tcaaatcaca acctgataca attgttattc ctcctcagtg gttccctaaa
    12601 atgccaacca tggaaaactt ccaacaactc atggtgcaga accctgcctt gcaatggatg
    12661 tggaactcag tatttatctc attggtaacc atgttcttag tctgtgcaac ctcatctcta
    12721 gcaggttatg tattggctaa aaaacgtttc tatggtcaac gcattctatt tgctatcttt
    12781 atcgctgcta tggcacttcc aaaacaagtt gtccttgtac cattggtacg tatcgtcaac
    12841 ttcatgggaa tccacgatac tctctgggca gttatcttgc ctttgattgg atggccattc
    12901 ggtgtcttcc tcatgaaaca gttcagtgaa aatatcccta cagagttgct tgaatcagct
    12961 aaaatcgacg gttgtggtga gattcgtacc ttctggagtg tagccttccc gattgtgaaa
    13021 ccagggtttg cagcccttgc aatctttacc ttcatcaata cttggaatga ctacttcatg
    13081 caattggtaa tgttgacttc acgtaacaat ttgaccatct cacttggggt tgcgaccatg
    13141 caggctgaaa tggcaaccaa ctatggtttg attatggcag gagctgccct tgctgctgtt
    13201 ccaatcgtca cagtcttcct agtcttccaa aaatccttca cacagggtat tactatggga
    13261 gcggtcaaag gataatactc tgcgaaaatc gaatgcaaac tacgtcagct tcaccttgcc
    13321 atacttaagt attgcctgtg gttagcttcc tagtttgttc ttcaattttc attgagtata
    13381 ggaaaatcaa tctatcaaga tacagaagta tattttatag atttagagaa tatagaagtt
    13441 ataagtgtct acaaaatgga gggtatgcag ttactttatg aagttttgtc agacacttat
    13501 caacttaaga atggttttag ttaactatca gaaacgaagg aaagagtatg atttttgacg
    13561 atttgaaaaa catcaccttt tacaaaggga ttcatcccaa tttagacaag gctatcgact
    13621 acctctacca acatcgtaaa gattcattcg aattaggaaa gtatgagatt gatggagata
    13681 aagtctttct agttgttcag gaaaatgtcc tcaatcaagt tgagaataat caatttgaac
    13741 accataagaa ctatgcagat ttgcatttgc tgatagaagg gcatgaatat tcgagctacg
    13801 gttcacgtat caaagacgag gcagtagcat tcgacgaagc gagtgacatt ggctttgttc
    13861 attgttatga acactaccca ctcttattgg gttatcacaa ttttgcgatt ttcttcccag
    13921 gtgagccaca tcagccaaat ggttatgcag gcatggaaga aaaggttcga aaatatctct
    13981 ttaaaatctt gattgattaa aaataggatg aattgttttt ttgtaaagct ttgataatac
    14041 tctaccatga aattgatctt tgtgaggtag agaaatgaga ataaaatatt taaaaattgg
    14101 tatcttctaa gtatgctgca agagctagtt tcttggatgg acagggaatt acagttgatg
    14161 agatggcttg gataattagg ggcattgtga atgcattgat tggtagatac ataaaattag
    14221 gtgcttatgc ggctaagtat ggtattagta tggcacgctc gatcttaagt agggcagctg
    14281 caactgcagc agcaagagta ggattatcga ccaagatttc tggatggatt ttacgagtag
    14341 ctgtgaatgt agctgatgta tatggtaatt ttgcctacaa tattgctgca gcttgggatg
    14401 cacatgataa aatccctaac aatggtcgta taaactttta aaatgcgaga atgaaagcac
    14461 tttgtatttt tttattgaat atgttagctt ggacagtgct tgcaatgata attcgtggag
    14521 ggctagatgg atttaatgag catacttgga gtactatttt aattgcttcg ctgttcgggg
    14581 tatatgatta taagcccata gataaaaata gaaaaaagtc caaaagaaaa aagaaaaaat
    14641 agatttgttc atggtaggga cttatgaaag ctttactgac aaaaaagaaa acagtttaca
    14701 aagaaaaatg atggaggagc aaacatggca caaaaaggag taagccttat caaggcagca
    14761 tttgatacag acaactttct catgcgtttt agtgagaaag tcttggacat cgtgacagcc
    14821 aatcttcttt ttgtcgtctc ttgtttgccc atcgtgacga ttggagtggc taaaatcagc
    14881 ctctacgaga ccatgttcga agttaagaag agcagacggg tgcctgtttt taaaatctat
    14941 ctaagatctt tcaagcaaaa tctgaaacta ggtcttcagc tgggtttaat ggagttagga
    15001 attgtgtttc ttaccctttc agatctctat cttttctggg gtcaaacagc tctgcccttc
    15061 caattgctga aagccatttg tttaggtatt ctgatttttc ttactatcgt gatgctggct
    15121 agttacccta tcgcggcacg ttatgaccta tcttggaaag aaattcttca aaaaggattg
    15181 atgttggcta gttttaactt tccttggttc ttcctcatgt tagccattct tgtcctcatt
    15241 gtgatggttc tttatctgtc cgccttcagt ctactcttag gtggctcagt cttcctactt
    15301 tttgggtttg gactattggt ctttatccag actggattga tggagaaaat tttcgcaaaa
    15361 taccaatagg agctttattt ctgaaactac tttcaaaggc tccaaacgct attctataag
    15421 cgagaaacta aaatctaagt gtctataaga tattgaaagc cttttcggga aagtgtatac
    15481 taaagaagta aagaaaaatc tgctttagca gaaaataaaa ataataggag aaaatctatg
    15541 tcagatttga aaaaatacga aggtgtcatt ccagccttct acgcatgtta tgatgatcaa
    15601 ggagaagtaa gcccagaacg tacgcgtgcc ttggttcaat acttcattga taaaggtgtt
    15661 caaggtcttt atgtcaatgg ttcttctggt gaatgtatct accaaagcgt tgaagatcgc
    15721 aagttgattt tggaagaagt catggcggta gccaaaggta aattgaccat cattgctcat
    15781 gttgcctgca acaatactaa agacagtatg gaacttgctc gccatgctga aagcttggga
    15841 gtagatgcta ttgcaacgat tccaccaatt tacttccgct tgccagaata ctcagttgcc
    15901 aaatactgga acgatatcag ttctgcagct ccaaacacag actacgtgat ttacaacatt
    15961 cctcaattgg caggggttgc tttgactcca agcctttaca cagaaatgtt gaaaaatcct
    16021 cgtgttatcg gtgttaagaa ctcttctatg ccagttcaag atatccaaac ctttgtcagc
    16081 cttggtgggg aagaccatat cgtctttaac ggtccagatg aacagttcct aggtggccgc
    16141 ctcatgggtg ctaaggctgg tatcggtggt acttatggtg ctatgccaga actcttcttg
    16201 aaactcaatc agttgattgc ggataaggac ctagaaacag cgcgtgaatt gcagtatgct
    16261 atcaacgcaa tcattggtaa actcacttct gctcatggaa atatgtacgg tgtcattaaa
    16321 gaagttttga aaatcaatga aggcttgaat attggatctg ttcgttcacc attgacacca
    16381 gtgactgaag aagatcgtcc agttgtagaa gcggctgctg ccttgattcg tgaaaccaag
    16441 gagcgcttcc tctaatctaa aaggaggtat ttatgacata ctacgttgca attgatatcg
    16501 gtggaaccaa catcaagtat ggtttggttg atcaagaggg gcaacttctt gaatcgcatg
    16561 aaatgccaac tgaggcgcat aagggtggac ctcatatctt acaaaagacc aaagatatcg
    16621 tagctagtta tttagaaaaa ggcctagtag caggtgttgc catatcttct gctgggatgg
    16681 tggatccgga taagggtgag attttctatg ctgggccgca aatccctaac tacgcaggca
    16741 cccagttcaa aaaggaaatc gaagaaagct ttactattcc ttgtgagatt gaaaatgatg
    16801 tcaactgtgc aggtcttgct gaggcagtat ctggttcagg caagggagca agtatgacac
    16861 tttgcttgac cattggaaca ggtatcggtg gttgcttgat tatggatagg aaagtcttcc
    16921 atggttttag caattcagcc tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc
    16981 aagacttggc ttctacaaca gctttagtga aatatgtagc tgaagcccat ggagaagatg
    17041 ttgatcagtg gaatggccgt agaattttca aagaagccac tgaaggaaac aaaatctgca
    17101 tggaaggtat tgaccgtatg gttgactatc taggaaaagg tctggcaaat atttgctacg
    17161 ttgccaatcc agaagtggtt attcttggtg gtggtatcat ggggcaagag gctatcctca
    17221 aacctaagat tcgcacagcc ttgaaagagg ctttggtacc aagtttagca gaaaaaacac
    17281 gattagaatt tgcccatcac caaaatacag cagggatgtt gggtgcatat tatcatttta
    17341 agacaaaaca atcctagttt ggctcagcca aactaggatt ttcttacacg tttttgtcta
    17401 cgatagccgt tgagtttttt attttcccag tagctattaa agattttttc cttgctttcg
    17461 cgattgattt ccaaaaagta ggcataaatc aaatcgataa agaagagcat aggaagttga
    17521 gcggatattc gttggatata ggagggttgg ctgtgggtgg ctacaagaac agtctctgta
    17581 taggtctggc tatttttatt gggaacactt gtaaagagta cagtctttgc ccccatctcc
    17641 ttggcatcta atagactatc taaaatagaa ggagttgagc ctgaaagtga gaagcccagt
    17701 actagacaat tttcatccat gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa
    17761 gcttcgcaga ccacgcctag tcgcataaaa cgtaatttca tttcacgggc gacgagacca
    17821 gaactccctg ttccaaagaa gtagatacgc tcagcatctt cgattagctg ggcaattcgt
    17881 tctagttgga tttcgtcaat caagtcttgt gtttgttccc tcatattgct ataacttctg
    17941 aggactcgtt tggtcagtgg actgtgcttg gagacttggt tggcttgatt ttctgcctga
    18001 tgttggtatt ggaaaataaa ttctcggtag ccagtaaagc cacacttttt agcaaagcgg
    18061 gtcaaagcag cttgagaaat atgtaatttt tgggtgactt gttgagaaga taaatcatct
    18121 gtaatcgttt cagcttgcaa aaaatagcga gcgatttctt gctctaggtc tgtcatttct
    18181 tcaaaatgtg aatcaatgat agttgcgata tctggtttgt ccatagggaa agctccttta
    18241 catgagtcat actggaagac tagatcaggg aatagtcaca cttcattata acacataata
    18301 taaggataga taaataaaaa cgcatttctg ttttaaaaac gaaaaaatcg aaaaagcttc
    18361 tctcttttcc ataattttct actcaaattg tggtacaatt aagagtaaga ttttaagtta
    18421 gaaatgagac tgatttgtat gagaaaattt aacagccatt cgattccgat tcggcttaat
    18481 ttattgtttt caatcgtcat tttactcttt atgaccatta ttggtcgttt gttgtatatg
    18541 caggttttga acaaggattt ttacgaaaaa aagctagcct cagctagtca gaccaagatt
    18601 acaagcagtt cagcccgtgg ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat
    18661 acgttaaagc aggttgtttc ctttacgcgt agcaataaaa tgacggctac agacttaaaa
    18721 gaaacagcta aaaagttact gacttatgtg agcatcagtt ctccaaattt gacagaacgc
    18781 cagctggcgg attactattt ggctgatcct gaaatctata aaaaaacagt ggaagctctc
    18841 ccaagcgaga aacgcttgga ttcagatgga aatcgtctat ccgaatcaga actgtataac
    18901 aatgcggtcg atagtgtcca aacaagtcaa ctaaactata cagaggatga aaagaaagaa
    18961 atctatcttt ttagtcagtt aaatgctgtt ggaaactttg cgacaggaac cattgctaca
    19021 gatcctctaa atgattctca ggtggctgtt attgcctcta tttcaaagga gatgcctggc
    19081 attagtattt ctacttcttg ggatagaaag gttttggaaa cttccctttc ttctatagtt
    19141 gggagtgtat ccagtgaaaa agctggtctc ccagcggaag aagcagaagc ctatcttaaa
    19201 aaaggctatt ctctaaatga ccgtgtagga acctcctatt tggaaaagca atatgaagag
    19261 accttacaag gaaaacgatc ggtaaaagaa atccatctgg ataaatatgg caatatggaa
    19321 agcgtggata caattgagga aggtagtaag ggaaacaata tcaaactgac cattgatttg
    19381 gccttccaag atagcgtgga tgctttgctg aaaagttatt tcaattctga gctagaaaat
    19441 ggtggagcca agtattctga aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg
    19501 gttttgtcta tgtcagggat taaacatgac ttgaaaacag gagagttgac gcctgattcc
    19561 ttgggaacgg taaccaatgt ctttgttcca ggttcggttg tcaaggcggc gaccatcagc
    19621 tcaggttggg aaaatggagt cttgtcagga aaccagacct tgacagacca gtccattgtc
    19681 ttccaaggtt cagctcccat caattcttgg tatactcagg cttacggttc attccctatc
    19741 acagcggtcc aagctctgga gtattcatca aatacctata tggtccaaac agccttaggt
    19801 cttatggggc aaacctatca acccaatatg tttgtcggca ccagcaatct agagtctgct
    19861 atggagaaac tgcgttcaac ctttggcgaa tatggcttgg gtactgcgac aggaattgac
    19921 ctaccagatg aatctactgg atttgttccc aaagagtata gctttgctaa ttacattact
    19981 aatgcctttg ggcagtttga taactatacg ccgatgcagt tggctcagta tgtagcaact
    20041 attgcaaatg atggtgttcg tgtggctcct cgtattgttg aaggcattta tggtaataat
    20101 gataagggag gactgggtga cttgattcag caactgcaac cgacagagat gaataaggtc
    20161 aatatatccg actccgatat gagcatcttg caccaaggtt tttatcaggt tgcccatggt
    20221 actagtgaat tgacaactgg acgtgccttt tcaaatggtg ccttggtatc cattagcgga
    20281 aaaacaggta cagccgaaag ctatgtggca gatggtcagc aagcaaccaa taccaatgcg
    20341 gtggcctatg ccccatctga taatccccaa atcgctgtcg cagtggtctt tcctcataat
    20401 accaatctaa caaatggtgt aggaccttcc attgcacgtg acattatcaa tctgtatcaa
    20461 aaataccatc caatgaacta gaaaggaaat tatgctttat ccaacaccta ttgccaagtt
    20521 gattgacagt tattctaagt taccaggtat cgggattaag acggctacgc gtctggcctt
    20581 ttatacgatt gggatgtctg ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc
    20641 taagagagaa ttgacatatt gttctatttg tggacgtttg acagacgacg atccttgttc
    20701 tatctgtact gatccgactc gtgaccagac aacaatttta gttcttgagg atagtagaga
    20761 tgtggcagcc atggaaaata tccaagaata ccatggactc tatcatgtcc ttcatggcct
    20821 catttctcct atgaatggta tcagtccgga cgatatcaat ctcaagagcc ttatgactcg
    20881 tcttatggat agtgaggttt cagaagtgat tgtggcgact aatgctacag cggatggtga
    20941 agcgacttcc atgtatcttt cacgtttgct caagccggct ggtatcaagg ttacgcgtct
    21001 agcacgaggt ctcgctgtgg gagcggacat tgagtatgcg gacgaagtga cactcttacg
    21061 agccattgaa aatcggacag agttgtaagt gtaggcaaat ttacgaactc cattcattta
    21121 taaaaaatca aagaggctgg aaatcgttcc tatcggcctc tttttgtata gtgtgatgag
    21181 taggatcagg ttcaagtttt aaaaaaccaa gcaaatatga tatactaaag agcgagtatt
    21241 ctagtagaat taggacaaat aatatgaaac aaacgattat tcttttatat ggtggacgga
    21301 gtgcggaacg cgaagtctct gtcctttcag ctgagagtgt catgcgtgcg gtcgattacg
    21361 accgcttcac agtcaagact ttctttatca gtcagtcagg tgactttatc aaaacacagg
    21421 aatttagtca tgctccgggg caagaagacc gtctcatgac caatgaaacc attgattggg
    21481 ataagaaagt tgcaccaagt gctatctacg aagaaggtgc agtggtcttt ccagtccttc
    21541 acgggccaat gggagaagat ggctctgttc aaggattctt ggaagttttg aaaatgcctt
    21601 acgttggttg caacattttg tcatcaagtc ttgccatgga taaaatcacg actaagcgtg
    21661 ttctggaatc tgctggtatt gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg
    21721 tgactgctaa aatcgctgaa gtggaagaaa aattggctta tccagtcttc actaagccgt
    21781 caaacatggg gtctagtgtc ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag
    21841 ccttagaact tgccttccga tatgatagcc gtgtcttggt tgagcaagga gtgaatgccc
    21901 gtgaaattga ggttggcctc ttgggtaact acgatgtcaa gagcacgcta ccaggagaag
    21961 ttgtcaagga cgttgccttt tatgactacg atgccaagta tattgataac aagattacta
    22021 tggatattcc tgccaaaatc agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa
    22081 cagccttccg tgccattggt ggccttggtc tatctcgttg cgatttcttc tatacagata
    22141 agggagagat ttttctcaac gagctcaata ccatgccagg tttcacccag tggtctatgt
    22201 acccactact ttgggacaat atggggatca gctacccaga actaatcgag cgtttggttg
    22261 accttgccaa ggaaagtttt gacaagcgcg aagcgcattt gatataaaat gaaagagagg
    22321 gtagaagcca gaaccatcac tgcaaggtga ctagagttct cggacttcag ccctttttaa
    22381 aggagtagaa atgaaattaa caatccatga aattgcccaa gttgttggag ccaaaaatga
    22441 tatcagtatc tttgaggaca cccagttaga aaaagctgag tttgatagtc gtttgattgg
    22501 aactggagat ttatttgtgc cacttaaagg tgcgcgtgat ggccatgact ttattgaaac
    22561 agcctttgaa aatggtgcag cagtaacctt gtctgagaaa gaggtctcaa atcatcctta
    22621 cattctagta gatgatgttt tgacagcctt tcaatcccta gcatcctact atcttgaaaa
    22681 aacgactgtt gatgtctttg ctgttacagg ttcaaatggc aagacaacga ctaaggatat
    22741 gttggcgcat ttactgtcaa caagatacaa gacctacaaa acacaaggca attacaataa
    22801 cgagattggc cttccttaca cagttcttca tatgcctgaa gggacagaaa agttggtctt
    22861 ggagatgggg caggatcact tgggagatat tcatctcttg tctgaactgg ctcgtccaaa
    22921 aacagccatc gtgaccttgg ttggagaagc tcatttggcc tttttcaaag atcgttctga
    22981 gattgctaaa ggaaaaatgc aaattgcgga cggaatggct tcaggttcct tgcttttagc
    23041 gccggctgac cctatcgtag aggactattt gccaactgat aaaaaagtgg ttcgttttgg
    23101 gcaaggggca gagctggaaa ttactgactt ggttgagcgc aaagatagtc tgaccttcaa
    23161 ggccaatttc ttagagcaag cccttgattt gccagtaact ggtaagtaca atgctaccaa
    23221 tgctatgatt gcatcctatg ttgccctaca agaaggagtt tcagaggagc aaatccgttt
    23281 ggccttccaa ggtcttgaat tgacgcgtaa tcgtactgag tggaagaaag cagccaatgg
    23341 agcagatatc ctgtcagacg tatataatgc caatccaact gctatgaagc tgattttaga
    23401 gactttctct gccattccag ccaatgaagg tggcaagaaa attgcagtgt tggcggatat
    23461 gaaggagctt ggtgaccagt ctattcaact ccataaccag atgattttga gcctttcgcc
    23521 agatgtgctt gataccgtta ttttctatgg agaagacatt gctgaattag cccaattggc
    23581 cagtcaaatg ttcccaattg gccacgttta ctacttcaag aaaacagaag accaagacca
    23641 atttgaagac ctagtcaagc aggtcaagga aagcctcagt gccaatgatc aaatcttgct
    23701 caagggctct aactctatga acctagccat gttggtagaa agtttagaaa atgaaaccaa
    23761 gtgattttgt taagtatctg caaagaatga ttgcccttac agatactggc ttaaccttta
    23821 caaaagatcc ttttgaccgt gagcgctacg aggacttgcg aagtctgtta tctgaaatgt
    23881 tgaatcaggg atcagacctg gatgcagaag aagtagcaga agtcttgaaa ccaacttcag
    23941 cttatgcgac tcccttaatg gacgtccgtg cttggattgt tgaggatgag aagatttgtc
    24001 tggttagggg acaaggagag gatagttggg ctttgccagg tggctttggt gaagtcggct
    24061 attctccaac tgaaaatatt ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag
    24121 ttgaaagact gctagctgtt tttgatacca atcgtttcca actacagagc aaacaatatg
    24181 caaagtttgt ttttgaatgt aagcttctcg atggacaatt ccaagaaaat caagaaatcg
    24241 ctgaccttca attttttgca attgaccaac tgccgaattt atctgaaaaa cgcattacca
    24301 aggagcaaat agagcttctt tggcaggttt atcaaggtca gagggagcaa tatcttgact
    24361 aagaagatga ttatcgtatt tctaaattca tttttcttaa gtagcatggt ataataaaat
    24421 gcaggaaaat tttgaatcat gaggaagact agatgaattt atgggatatt ttctttacga
    24481 ctcaggcaac cgagccgccc aaatttgacc ttttttggta tgttagccta tttacgctct
    24541 tagccttaac cttttataca gcccatcgct atcgtgaaaa gaaggtttac caacgatttt
    24601 tccaaatctt gcagactgtt cagttaatcc ttctttatgg ttggtactgg gtcaatcata
    24661 tgccactgtc agaaagccta cccttttacc attgccgtat ggctatgttt gtggtactct
    24721 tgcttcctgg tcagtccaaa tataaacaat actttgcatt attgggaaca tttgggacat
    24781 tagcagcctt tgtttatcca gtgccagatg cttacccttt tccacatatc accattctat
    24841 cctttatctt tggtcattta gcactcttgg ggaactctct agtttatcta ttgagacagt
    24901 ataatgcgcg attgctggat gtgaagggaa tttttctcat gacctttgcc ctaaatgcct
    24961 tgatttttgt ggtcaatttg gtgacaggtg gcgattacgg atttttgaca aaaccgccat
    25021 tggttgggga tcacggtcta gtagctaatt atttacttgt ttcaattgtg ctggtagcta
    25081 ctatcagttt gactaagaaa atcttagaat tctttttagc tcaagaagca gaaaaaatga
    25141 ttgcaaagga agcttaacac agagctttct tttttgctct tagagagttt ttacaagcag
    25201 cttataaaat aagaatttct gaatagacaa actcaaaaaa tggctgggaa atttaggaaa
    25261 aaagcaagca cgattaaatt ttttgtgtta taatattttg tgaatagcta tgcctatgtt
    25321 tagctatgga ataatacgaa gtgcgaaact tggaagatag agaggaagcg atgtaatggc
    25381 tagagaaggc ttttttacag gtctagatat tggaacaagc tctgtcaagg tgcttgtggc
    25441 cgagcagaga actggtgaat taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt
    25501 aaaggatgga attattgttg atattgatgc agcagcaact gctatcaagt cagccatttc
    25561 ccaagcggaa gaaaaggcag gcatttcgat taaatcagta aatgtcggct tgcctggtaa
    25621 tcttttgcag gtagaaccaa ctcaggggat gattccagta acatctgata ctaaggaaat
    25681 tacggatcaa gatgttgaaa atgttgtcaa atcagctttg acaaagagta tgacacctga
    25741 ccgtgaagtc attaccttta ttcctgaaga atttattgtg gatggtttcc aagggattcg
    25801 tgacccacgt ggcatgatgg gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc
    25861 tcgtactatc ttgcacaatt tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa
    25921 tgttatcatt tcaccactag caatggttca gtctgttttg aacgaagggg aacgtgaatt
    25981 tggtgctaca gtgattgata tgggggcagg tcaaacgact gtcgctacaa tccgtaatca
    26041 agaactccag ttcacacata ttctccaaga aggtggagat tatgtaacta aagatatctc
    26101 caaggttttg aaaacctctc gcaaattagc ggaaggcttg aaactgaatt acggggaagc
    26161 ctatccgcct cttgcaagca aagaaacctt ccaagtagag gttattggag aagtagaagc
    26221 agtcgaagtg acggaagcct acttgtcaga aattatttct gcacgaatca agcacatcct
    26281 tgaacaaatc aagcaagaat tagatagaag gcgtctattg gacctccctg gtggtattgt
    26341 cttaatcggt gggaatgcca ttttaccagg tatggttgag cttgctcagg aagtctttgg
    26401 cgtccgtgtc aagctttatg ttccaaatca agttggtatc cgtaatccag cctttgcgca
    26461 tgtgattagt ttatcagaat ttgcgggtca attaacagaa gttaatcttt tggctcaggg
    26521 agcgataaaa ggtgagaatg acttaagtca tcagccaatt agttttggtg ggatgctgca
    26581 aaaaacagct cagtttgtac aatcaacgcc tgttcaacca gctcctgctc cagaagtaga
    26641 gccggtggcg cctacagaac caatggcgga tttccaacaa gcttcacaaa ataaaccgaa
    26701 attagcagat cgtttccgtg gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat
    26761 aaattatgac attttcattt gatacagctg ctgctcaagg ggcagtgatt aaagtaattg
    26821 gtgtcggtgg aggtggtggc aatgccatca accgtatggt cgacgaaggt gttacaggcg
    26881 tagaatttat cgcagcaaac acagatgtac aagcattgag tagtacaaaa gctgagactg
    26941 ttattcagtt gggacctaaa ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg
    27001 gtcgtaaagc cgctgaagaa agcgaagaaa cactgacgga agctattagt ggtgccgata
    27061 tggtcttcat cactgctggt atgggaggag gctctggaac tggagctgct cctgttattg
    27121 ctcgtatcgc caaagattta ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt
    27181 ttgaaggaag taagcgtgga caatttgctg tagaaggaat caatcaactt cgtgagcatg
    27241 tagacactct attgattatc tcaaacaaca atttgcttga aattgttgat aagaaaacac
    27301 cgcttttgga ggctcttagc gaagcggata acgttcttcg tcaaggtgtt caagggatta
    27361 ccgatttgat taccaatcca ggattgatta accttgactt tgccgatgtg aaaacggtaa
    27421 tggcaaacaa agggaatgct cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg
    27481 tagaagcggc acgtaaggca atctattcac cacttcttga aacaactatt gacggtgctg
    27541 aggatgttat cgtcaacgtt actggtggtc ttgacttaac cttgattgag gcagaagagg
    27601 cttcacaaat tgtgaaccag gcagcaggtc aaggagtgaa catctggctc ggtacttcaa
    27661 ttgatgaaag tatgcgtgat gaaattcgtg taacagttgt cgcaacgggt gttcgtcaag
    27721 accgcgtaga aaaggttgtg gctccacaag ctagatctgc tactaactac cgtgagacag
    27781 tgaaaccagc tcattcacat ggctttgatc gtcattttga tatggcagaa acagctgaat
    27841 tgccaaaaca aaatccacgt cgtttggaac caactcaggc atctgctttt ggtgattggg
    27901 atcttcgccg tgaatcgatt gttcgtacaa cagattcagt cgtttctcca gtcgagcgct
    27961 ttgaagcccc aatttcacaa gatgaagatg aattggatac acctccattt ttcaaaaatc
    28021 gttaagtaaa tgaatgtaaa agaaaataca gaacttgttt ttcgagaagt tgcagaggct
    28081 agtctgagtg ctcatcgaga gagtggttcg gtctctgtca ttgcagttac caagtatgta
    28141 gatgtaccga cagcggaagc cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt
    28201 gtagataagt ttctggaaaa atatgaagct ttaaaagatc gagatgtgac ttggcatttg
    28261 attggtacct tgcaaagacg taaggtgaaa gatgtcattc aatacgttga ttatttccat
    28321 gcattggact cagtaaagct agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag
    28381 tgtttccttc aagtaaatat ttctaaagaa gaaagcaaac acggtttttc gagagaggaa
    28441 ctgctggaaa tcttgccaga gttagccaga ctagataaga ttgaatatgt tggtttaatg
    28501 acgatggcac cttttgaggc tagcagtgag cagttgaaag agattttcaa ggcgacccaa
    28561 gatttacaaa gagaaattca agagaaacaa attccaaata tgcctatgac cgagttaagt
    28621 atgggaatga gtcgtgatta taaagaagcg attcaattcg gttccacttt tgttcgtata
    28681 ggtacatcat tttttaagta ggagagaacc atgtctttaa aagatagatt cgatagattt
    28741 atagattatt ttacggagga tgaggattca agtctccctt atgaaaaaag agatgagcct
    28801 gtgtttactc cagtaaattc ttcacaggaa ccggctctcc caatgaatca accttcacag
    28861 tcggctggta caaaagagaa caatatcacc agacttcatg caagacaaca ggaattggca
    28921 aatcagagtc agcgtgcaac ggataaggtc attatagatg ttcgttatcc tagaaaatat
    28981 gaggatgcaa cagaaattgt tgatttattg gcaggaaacg aaagtatctt gattgatttt
    29041 cagtatatga cagaggtgca ggctcgtcgt tgtttggact atttggatgg agcttgtcat
    29101 gttttagctg gaaatttgaa aaaggtagct tctaccatgt atttgttgac accagtgaat
    29161 gttattgtaa atgttgaaga tatccgttta ccagatgaag atcaacaggg tgagttcggt
    29221 tttgatatga agcgaaatag agtacgataa tgattttttt aattcgtatg atttataatg
    29281 cagtggatat ttactccctg attttggtag ccttcgctgt catgtcttgg tttccaggtg
    29341 cctacgaatc cagtttaggt cgttggattg tagcgttggt gaaaccagtg cttgctccct
    29401 tgcaacgcct gcctttacag atagcgggtc ttgatttatc tgtttgggtc gcgattgttt
    29461 tggttcgatt tttaggagaa aacctagtgc gttttctggc gatgatagga tgaataaagg
    29521 gatttattag catttctcca tagaagatcg tccatttctt gacaagggaa tggaatggat
    29581 aaagaaggta gaagatagct atgctccttt tttaactcct tttatcaatc ctcatcagga
    29641 gaagctatta aagattttgg ccaaaaccta tggtcttgct tgtagcagta gtggggaatt
    29701 cgtctcgagt gagtatgttc gagttttatt atacccagat tatttccaac cagagttttc
    29761 agattttgaa atatctctcc aggaaattgt gtattccaat aaatttgaac atttaacgca
    29821 tgctaagatt ttagggacag tcatcaatca attagggatt gaacggaaac tttttggaga
    29881 tatcctagta gatgaagaac gggcgcagat tatgattaat cagcagtttc ttcttctctt
    29941 tcaagatgga ctaaagaaaa ttggtcgtat acctgtttcg ctggaggaac gtcctttcac
    30001 cgagaaaata gataagctag aacagtatcg agaactggat ttatctgtgt ctagttttcg
    30061 attagatgtt cttttatcaa atgttttgaa actatctagg aatcaagcaa accagttgat
    30121 tgaaaagaaa cttgtccaag taaattatca tgtggtagac aaatcagatt acactgttca
    30181 agttggagac ttgattagtg tgagaaaatt tggtcgcttg agattacttc aagataaggg
    30241 acaaacgaaa aaagagaaga aaaaaataac cgtccagtta ttattaagta agtgaggaat
    30301 agaatgccaa ttacatcatt agaaataaag gacaagactt ttggaactcg attcagaggt
    30361 tttgatccag aagaagtcga tgaattttta gatattgtgg ttcgtgatta cgaagatctt
    30421 gtgcgtgcga atcatgataa aaatttgcgt attaagagtt tagaagagcg tttgtcttac
    30481 tttgatgaaa taaaagattc attgagccag tctgtattga ttgctcagga tacagctgag
    30541 agagtgaaac aggcggcgca tgaacgttca aacaatatca ttcatcaagc agagcaagat
    30601 gcgcaacgct tgttggaaga agctaaatat aaggcaaacg agattcttcg tcaagcaact
    30661 gataatgcta agaaagtcgc tgttgaaaca gaagaattga agaacaagag ccgtgtcttc
    30721 caccaacgtc tcaaatctac aattgagagt cagttggcta ttgttgaatc ttcagattgg
    30781 gaagatattc tccgtccaac agctacttat cttcaaacca gtgatgaagc ctttaaagaa
    30841 gtggttagcg aagtacttgg agaaccgatt ccagttccaa ttgaagaaga accaattgat
    30901 atgacacgtc agttctctca agcagaaatg gaagaattac aagctcgtat tgaggtagcc
    30961 gataaagaat tgtctgaatt tgaagctcag attaaacagg aagtggaagc tccaactcct
    31021 gtagtgagtc ctcaagttga agaagagcct ctgctcatcc agttggccca atgtatgaag
    31081 aaccagaagt agctccagtg catccgacag gtccaacacc agctacagaa actgttgatt
    31141 cagcaccggg atttgaagca ccgcaagaat ctgttacaat tttataagaa atattctgag
    31201 aacaatatct tatccttata ttcccagcga gcaggagatg gtgtgagtcc tgcattccct
    31261 atcgataaga ttatcctctc aaaaactcaa gtctgaatct agtaagattt gacgttcccc
    31321 acgttacggg ataagaggga gaaagactaa aactttttcc gaataaaggt ggtaccacga
    31381 ttttcgtcct ttttggaagt tgtggttttt aatttgttat tatttataaa ggagatacca
    31441 tgaaactcaa agacaccctt aatcttggga aaactgaatt cccaatgcgt gcaggccttc
    31501 ctaccaaaga gccagtttgg caaaaggaat gggaagatgc aaaactttat caacgtcgtc
    31561 aagaattgaa ccaaggaaaa cctcatttca ccttgcatga tggccctcca tacgctaacg
    31621 gaaatatcca cgttggacat gctatgaaca agatttcaaa agatattatt gttcgttcta
    31681 agtctatgtc aggattttac gcaccattta ttcctggttg ggatactcat ggtctgccaa
    31741 tcgagcaagt attgtcaaaa caaggtgtca aacgtaaaga aatggacttg gttgagtact
    31801 tgaaactttg ccgtgagtac gctctttctc aagtagataa acaacgtgaa gattttaaac
    31861 gtttgggtgt ttctggtgac tgggaaaatc catatgtgac cttgactcct gactatgaag
    31921 cagctcaaat tcgtgtattt ggtgagatgg ctaataaggg ttatatctac cgtggtgcca
    31981 agccagttta ctggtcatgg tcatctgagt cagcccttgc tgaagcagag attgaatacc
    32041 atgacttggt ttcaacttcc ctttactatg ccaacaaggt aaaagatggc aaaggagttc
    32101 tagatacaga tacttatatc gttgtctgga caacgactcc atttaccatc acagcttctc
    32161 gtggtttgac ggttggtgca gatattgatt acgttttggt tcaacctgct ggtgaagctc
    32221 gtaagtttgt cgttgctgct gaattattga ctagcttgtc tgagaaattt ggctgggctg
    32281 atgttcaagt tttggaaact taccgtggcc aagaactcaa ccacatcgta acagaacacc
    32341 catgggatac agctgtagaa gagttggtaa ttcttggtga ccacgttacg actgactctg
    32401 gtacaggtat tgttcataca gcccctggtt ttggtgagga cgattacaat gttggtattg
    32461 ctaataatct tgaagtcgca gtgactgttg atgaacgtgg tatcatgatg aagaatgctg
    32521 gtcctgaatt tgaaggtcaa ttctatgaaa aggtagttcc aactgtgatt gaaaaacttg
    32581 gtaacctcct tcttgcccaa gaagaaatct ctcactcata tccatttgac tggcgtacta
    32641 agaaaccaat catctggcgt gcagttccac aatggtttgc ctcagtttct aaattccgtc
    32701 aagaaatctt ggacgaaatt gaaaaagtga aattccactc agaatggggt aaagtccgtc
    32761 tttacaatat gatccgtgac cgtggtgact gggttatctc tcgtcaacgt gcttggggtg
    32821 ttccacttcc tatcttctac gctgaagatg gtacagctat catggtagct gaaactattg
    32881 aacacgtagc tcaacttttt gaagaacatg gttcaagcat ttggtgggaa cgtgatgcca
    32941 aagacctctt gccagaagga tttactcatc caggttcacc aaacggcgag ttcaaaaaag
    33001 aaactgatat catggacgtt tggtttgact caggttcatc atggaatgga gtggtggtaa
    33061 accgtcctga attgacttac ccagccgacc tttacctaga aggttctgac caataccgtg
    33121 gttggtttaa ctcatcactt atcacatctg ttgccaacca tggcgtagca ccttacaaac
    33181 aaatcttgtc acaaggtttt gcccttgatg gtaaaggtga gaagatgtct aaatctcttg
    33241 gaaataccat tgctccaagc gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct
    33301 gggtaacaag tgttgactca agcaatgacg tgcgtatctc tatggatatt ttgagccaag
    33361 tttctgaaac ttaccgtaag attcgtaaca ctcttcgttt cttgattgcc aatacatctg
    33421 actttaaccc agctcaagat acagtcgctt acgatgagct tcgttcagtt gataagtaca
    33481 tgacgattcg ctttaaccag cttgtcaaga tcattcgtga tgcctatgca gactttgaat
    33541 tcttgacgat ctacaaggcc ttggtgaact ttatcaacgt tgacttgtca gccttctacc
    33601 ttgattttgc caaagatgtt gtttacattg aaggtgccaa atcactggaa cgccgtcaaa
    33661 tgcagactgt cttctatgac attcttgtca aaatcaccaa actcttgaca ccaatccttc
    33721 ctcacactgc ggaagaaatt tggtcatatc ttgagtttga aacagaagac ttcgtccaat
    33781 tgtcagaatt accagaggct caaacttttg ctaatcaaga agaaatcttg gatacatggg
    33841 cagccttcat ggacttccgt ggacaagctc aaaaagcctt ggaagaagct cgtaatgcaa
    33901 aagtaatcgg taaatcactt gaagcacact tgacagttta tccaaacgaa gttgtgaaaa
    33961 ctctactcga agcagtaaac agcaatgtgg ctcaactttt gatcgtgtca gacttgacca
    34021 tcgcagaagg accagctcca gaagctgccc ttagcttcga agatgtagcc ttcacagttg
    34081 aacgcgctgc aggtgaagta tgtgaccgtt gccgtcgtat tgacccaaca acagcagaac
    34141 gtagctacca ggcagttatc tgtgaccact gtgcaagtat cgtagaagaa aactttgcag
    34201 atgcagtcgc agaaggattt gaagagaaat aagattgaaa agtctaggca aaattcaatt
    34261 tgagaagaaa agacaactaa ttttatagtc tattaaacgc attgtatcac gtttttgaac
    34321 acctgatatg atgcgttttt tatttttaaa atttgcaagg tgtgactttt tatactcata
    34381 ctcaatgaaa atcaaaaagc aaactaggaa gctagccgca ggctgctcaa aacactgttt
    34441 tgaggttgta gataagactg acgaagtcag taacatatat atggtaaggc gacgctgacg
    34501 tggtttgaag agattttcga agagtatcaa caagaatcaa agagaaactt agcaagctaa
    34561 cagtagtaag ataaaatagg aatttgatat t
//
LOCUS       DAVLZG010000017        33876 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLZG010000017 DAVLZG010000000
VERSION     DAVLZG010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.017"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(1..503)
                     /locus_tag="VYO72_000769"
                     /pseudo
     CDS             complement(1..503)
                     /locus_tag="VYO72_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(579..1019)
                     /locus_tag="VYO72_000770"
     CDS             complement(579..1019)
                     /locus_tag="VYO72_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1707175.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLRQ"
     gene            1010..1317
                     /locus_tag="VYO72_000771"
                     /pseudo
     CDS             1010..1317
                     /locus_tag="VYO72_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1340..1690)
                     /gene="tnpB"
                     /locus_tag="VYO72_000772"
     CDS             complement(1340..1690)
                     /gene="tnpB"
                     /locus_tag="VYO72_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1707176.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1671..1856)
                     /locus_tag="VYO72_000773"
     CDS             complement(1671..1856)
                     /locus_tag="VYO72_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707177.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2160..3722)
                     /gene="guaA"
                     /locus_tag="VYO72_000774"
     CDS             complement(2160..3722)
                     /gene="guaA"
                     /locus_tag="VYO72_000774"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1707178.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3864..4562
                     /locus_tag="VYO72_000775"
     CDS             3864..4562
                     /locus_tag="VYO72_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1707179.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4605..5501)
                     /locus_tag="VYO72_000776"
     CDS             complement(4605..5501)
                     /locus_tag="VYO72_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1707180.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILHIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5510..6445)
                     /locus_tag="VYO72_000777"
     CDS             complement(5510..6445)
                     /locus_tag="VYO72_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1707181.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARFLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6442..7167)
                     /locus_tag="VYO72_000778"
     CDS             complement(6442..7167)
                     /locus_tag="VYO72_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1707182.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7251..7886)
                     /locus_tag="VYO72_000779"
     CDS             complement(7251..7886)
                     /locus_tag="VYO72_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1707183.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7888..8715)
                     /locus_tag="VYO72_000780"
     CDS             complement(7888..8715)
                     /locus_tag="VYO72_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1707184.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8737..9663)
                     /locus_tag="VYO72_000781"
                     /pseudo
     CDS             complement(8737..9663)
                     /locus_tag="VYO72_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10314..10925
                     /locus_tag="VYO72_000782"
     CDS             10314..10925
                     /locus_tag="VYO72_000782"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1707185.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10970..11698
                     /gene="rlmB"
                     /locus_tag="VYO72_000783"
     CDS             10970..11698
                     /gene="rlmB"
                     /locus_tag="VYO72_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1707186.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11737..12648)
                     /gene="trxB"
                     /locus_tag="VYO72_000784"
     CDS             complement(11737..12648)
                     /gene="trxB"
                     /locus_tag="VYO72_000784"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1707187.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12714..12938)
                     /locus_tag="VYO72_000785"
     CDS             complement(12714..12938)
                     /locus_tag="VYO72_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1707188.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAGARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13016..13759)
                     /locus_tag="VYO72_000786"
     CDS             complement(13016..13759)
                     /locus_tag="VYO72_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1707189.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13759..14559)
                     /locus_tag="VYO72_000787"
     CDS             complement(13759..14559)
                     /locus_tag="VYO72_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1707190.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14717..15073)
                     /locus_tag="VYO72_000788"
     CDS             complement(14717..15073)
                     /locus_tag="VYO72_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1707191.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLSVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15086..15598)
                     /locus_tag="VYO72_000789"
     CDS             complement(15086..15598)
                     /locus_tag="VYO72_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1707192.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15598..16092)
                     /locus_tag="VYO72_000790"
     CDS             complement(15598..16092)
                     /locus_tag="VYO72_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707193.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16227..16673
                     /locus_tag="VYO72_000791"
     CDS             16227..16673
                     /locus_tag="VYO72_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1707194.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMINNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16670..17317
                     /locus_tag="VYO72_000792"
     CDS             16670..17317
                     /locus_tag="VYO72_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1707195.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKNVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17338..17919)
                     /gene="pdxT"
                     /locus_tag="VYO72_000793"
     CDS             complement(17338..17919)
                     /gene="pdxT"
                     /locus_tag="VYO72_000793"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1707196.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLLIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17920..18795)
                     /gene="pdxS"
                     /locus_tag="VYO72_000794"
     CDS             complement(17920..18795)
                     /gene="pdxS"
                     /locus_tag="VYO72_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1707197.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18947..20326)
                     /locus_tag="VYO72_000795"
     CDS             complement(18947..20326)
                     /locus_tag="VYO72_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1707198.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20620..21543
                     /locus_tag="VYO72_000796"
     CDS             20620..21543
                     /locus_tag="VYO72_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1707199.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     IFWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21603..22208
                     /locus_tag="VYO72_000797"
     CDS             21603..22208
                     /locus_tag="VYO72_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1707200.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22227..23471
                     /locus_tag="VYO72_000798"
     CDS             22227..23471
                     /locus_tag="VYO72_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1707201.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23587..23844)
                     /locus_tag="VYO72_000799"
     CDS             complement(23587..23844)
                     /locus_tag="VYO72_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1707202.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23886..25922)
                     /locus_tag="VYO72_000800"
     CDS             complement(23886..25922)
                     /locus_tag="VYO72_000800"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1707203.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26134..27051)
                     /gene="glyQ"
                     /locus_tag="VYO72_000801"
     CDS             complement(26134..27051)
                     /gene="glyQ"
                     /locus_tag="VYO72_000801"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1707204.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27419..28180)
                     /locus_tag="VYO72_000802"
     CDS             complement(27419..28180)
                     /locus_tag="VYO72_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1707205.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFFTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKIFPLLDWFVQQKLIEKEI"
     gene            complement(28453..29295)
                     /locus_tag="VYO72_000803"
     CDS             complement(28453..29295)
                     /locus_tag="VYO72_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1707206.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29409..30800)
                     /locus_tag="VYO72_000804"
     CDS             complement(29409..30800)
                     /locus_tag="VYO72_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1707207.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYSSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31035..31412)
                     /locus_tag="VYO72_000805"
     CDS             complement(31035..31412)
                     /locus_tag="VYO72_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1707208.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMSYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31645..32622
                     /locus_tag="VYO72_000806"
     CDS             31645..32622
                     /locus_tag="VYO72_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1707209.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYSKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGTLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQDPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32619..33701
                     /locus_tag="VYO72_000807"
     CDS             32619..33701
                     /locus_tag="VYO72_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1707210.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTLIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33765..>33876)
                     /locus_tag="VYO72_000808"
     CDS             complement(33765..>33876)
                     /locus_tag="VYO72_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1707211.1"
                     /translation="KNKAFRTLEDVIQGLEKEVIKSIVNRKWTRMLFESR"
BASE COUNT        10036 a         7599 c         6112 g        10129 t
ORIGIN      
        1 taatagctct tgctttagct ccttcaaaac tttgagaaaa aaccaccctc gcttttttaa
       61 actgagctta ggctaaaaga gtccagtgga ctcttttact ccgtcccata accaatgatt
      121 taatggcgcg ttcagctaga ttattggaaa ggaccagatg tccgtctttt aaaatggtct
      181 taaaggtttc ttcatacttg aggctgtatt caattgccct tcctggtttt gaacctgcta
      241 aaactgactg acggcggcac caagcaaaga agtcttccat taagggctgg acgtttctgt
      301 agtcgttcat cagctggcaa agcctcccag tctctttcca aggcaaataa ctggtcacga
      361 taggctaaac ctttagctcc taaggatgat ttatctgctt gcttgggggt cgcttcaaaa
      421 aatttccttc tcacatgcgc ccaacatcca acaagttcag cttcttccag ttgacgataa
      481 gcttctagcg gttcgcagtt taccaagctt agcgtcgcct tgctcctaaa ccttagactg
      541 ctatcgcata ggcagaacta gaggactaaa gttctaagtt actgccgcaa catatcacaa
      601 tgcatatagc cagaataatt tcctaggaat tcttgcacta ccgaaccact ccgacgctga
      661 tcatggtggt acagcgtaat cccttgtttc tcagctttcc cagacaaaaa agtccaatag
      721 taagtcagct gactatcact ttctaagacc cgataagagg tttcatctgc atgaagaaga
      781 gcttgttcta acaacttttc tcgtaaaagg ttataaaggg gctccaaata gtattgactc
      841 gtcttgatat gccaattaga gatttcctta cgtgtgattg gtaaacccat cctagcccaa
      901 tcttcttctt ggcgataatt gggtaccttc agattaaact tctgatggat ggtgtgagcg
      961 ataatagaag ctgagccaag gctatgcgcc aaaggggctt taggaatagg agctttcaca
     1021 agcttatcca gatgattatc ttttactcgt tatggacaat gctatatggc ataaatcaag
     1081 taccttaaag attccgacta atattggctt tgcatttatt cctccataca caccagagat
     1141 gaacccattg aacaagtgtg gaaagagatt cgtaaacgtg gatttaagaa taaagccttt
     1201 caaactttgg aagatgtcat gaatcaactt caagatgtta tacaaggact ggagaaggag
     1261 gtgataaagt ccatcgttaa tcggagatgg actagaatgc tttttgaaag cagatgagta
     1321 taaaaagaaa gtcctcattt caatagaaat cacgactttc tgataaattt attttgggag
     1381 tgatagaaaa gcccttcata agccaatcta cttgttcagg tgtgagagct ttgacatcct
     1441 tttctgtact gggccaagtc agtctgccgt tctcaaagcg tttatatagt agccaaaatc
     1501 cttgaccatc ccagtaaagg gctttaaagc ggtctttacg tccaccacaa aagagaaaaa
     1561 cttgaccgga gaaaggatcc aattcaaagt gggttttaac cagataagcc agtgaatcga
     1621 ttccttgtct catatcagtc ttcccacaca cgagatagac ctgccctagg ctagatagat
     1681 gaattgtcat agagcaacac cttatccaaa agctgttcta ccatttcgag attgagagat
     1741 tgaaaaaaac ttacttcaag cttgccaata cgaattttaa gcagaatatc atttctcttt
     1801 ttagaatcaa aaggacgaga ttgtggaatc tctacaggaa caataggttg tggcattaaa
     1861 atatcctcca atagttttac tttactaata gtatacagga ggaactccat gaatgataga
     1921 taccttgtta tgacgcgctt actatattag aaagttggct ctctaattaa attaattctc
     1981 attatatata tcaaaagacc gcagtttgaa aactacggtc taattttttg tccaaatgta
     2041 aatcacttgg aactattatt caatttattc tttttagtaa atgttcccgt tttaatccca
     2101 gttacagttt ttaatcctct gtaaccgttg attttacaaa gcttttaatt tttttgcgat
     2161 tactcccact caactgttgc aggtggttta cttgtaatat cgtagacgat acggttaaca
     2221 tgatccactt catttacgat acgtactgag attttttgaa gtacttccca tggaattttg
     2281 gcaaaatcag cagtcatacc atcgatagaa gtgatagcac ggattgcaat cgtgtagtca
     2341 tacgtacgac cgtcacccat aacaccgact gaacgaacgc ctgtgttaac agtgaagtat
     2401 tgccaaatat cgcggtcaag tccagcttta gcgatttctt cacgaagaat agcgtctgat
     2461 tcacgaacgg tttcaagttt ctcttcagtg atttcaccca tgacacggat agcaagtcct
     2521 ggtcctggga atggttggcg ccatacgata tggtctggca taccaagctc tgtaccaaga
     2581 gcacgaactt catccttgta aagagtattg agtggttcaa tcaattcaaa ctgcatatct
     2641 tctggaagac cacccacgtt gtggtgtgac ttgatagttt gagctgtatc cgtaccagac
     2701 tcgataacat ctgtatataa agtaccttga gcaaggaatt tcacatcttt gagcttgctt
     2761 gcttcgtcat cgaatacata gacaaactcg ttaccaatga ttttacgttt ttgttcagga
     2821 tcagaaacgc cagcaagttt gtcaaggaaa cgtttagcag cgtctgcttt gacgatattc
     2881 aaaccaaact taccaccgag catgtccata acttgatcag cttcgccttt acgaagaaga
     2941 ccgtggtcta cgaagataca gatcaattga tcgccaatcg ctttttggag aagaacccca
     3001 acgacagatg agtcaacacc acctgataga ccaagaagga cacgtttatc accgacggtt
     3061 tcacgaattt ttttgatctg catgtcaatg aaattatcca ttgaccagtc acctttagcc
     3121 ttacaaatgt taagggcaaa gttacgaagg atatcatttc cgtatacaga atgacgaact
     3181 tctgggtgga attggatacc gtaaatgtgt ttatctgggt tttcgatggc tgcgtatggg
     3241 cagtcagctg atgtacctgt acgaacaaag tcagcaggaa tctcagtaac cgcatcacca
     3301 tggctcatca aaacagtctg ttcatcaggt gttgattcaa aaagcgctga tggtgtgtga
     3361 gttagggttg attgaccgta ttcacgattt ccagcatcac ctgcaggaac aacttttcct
     3421 ccaagtttat gggtcaataa ctgcatacca taacagattc ccaaaattgg aattccgagt
     3481 tcgaagattt ctgggtcaat atcaaatgaa ccatcttcat atacagaatt tggaccacct
     3541 gatagaataa ttcctacagg attgacttca cgaacttcag cagctgaaat tttatggctt
     3601 tttagttctg aaaaaacacc aatctcacgg atacggcgtg aaatcagctg gttgtactgg
     3661 ctaccatagt ccaatacgat gattttttct acatcttgca aatcagttga aatgttgctc
     3721 atctttttcc tttctcaaaa gaaatatctt ttctcaatat tctatcacaa ataagggcga
     3781 attaccaact aaacaaggcg aagtttgact ttttctagtt tattggggta caatagagaa
     3841 aagatagaaa tgaagtgaaa aatatgctac ctgcttatat gaaaatccat gatcagataa
     3901 aaaaggatat tgacgagcac cgttgggcta ttggtgagag gcttcccagt gaaagagatt
     3961 tagctgagca gtttgcggtc agtcgcatga ccctccgcca agccgtatct ctattagtcg
     4021 aagaaggcgt cttagagcgc cgtgtaggaa gcggcacctt tgtttccagt actcgagtac
     4081 aagaaaagat gcgagggaca accagtttta ctgaaattgt caaatcccaa ggtaaagttc
     4141 cctctagcca gctcatttcc tacaaaaaaa ccattcccaa tgagcaagaa gttgccaagc
     4201 taggaatttt tccaacggac aatattatcc gaatggagcg ggtccgctat gccgaccaag
     4261 ttcccctagt ttatgaagtt gcttctattc ctgaaaaatt cattaaggac tttaaaaaag
     4321 aagaaatcac cagtcatttc ttccaaacct tgcaaaaaca tggctatcgt atcggtaaat
     4381 cccaacagac catctatgct cgccttgcta aagaaaagat tgcccactat ttggaagttg
     4441 aaaaaggaca tgctattctt ggattgaccc agatttccta cctagaagat ggtactgctt
     4501 ttgaatacgt aaaaagtcaa tatgtaggcg aacgctttga attttatctt gaaaataatt
     4561 agattaccac gcaaaaactc tctgtcacgg acaaagagtc ttttttattt ttctaagaat
     4621 aaatctttca aagaaatcaa agttacagca aacaatatca ttgccatacc aagaaaatca
     4681 atgggataaa attgttcatt cattattaag aaggcaaaga aaatcgccga tattggctca
     4741 attgaagcca acaagcttga cttgaccggt cctatcagac tggctccttt aaggaaagct
     4801 gtataggcaa agacagtccc gataaggata atgcctgcaa acgcaaggag aaaatcaaga
     4861 ctagtcggga tatcggcctg tagaacccct gtaaaaggaa gggcgaccaa acctgctatg
     4921 accattccca caccaatgac caagctgctc ccccactttt taatcaaggc tatgtgtaaa
     4981 atgatataca aagcataagt caaggcagaa aagagacccc agaacagacc agcaggtgtc
     5041 atggataact ggtccaactg cccatgtgtt gcgatcagga aggttcctcc gatggcgaat
     5101 atgatggaaa ctatctctcc cagtgtcggt gccaccctat ccttgataca gctataaatt
     5161 aaaattccga caggacaaac atactgaagc accgtcgctg ttcccgcatt ggtctcctga
     5221 atagcagaca gataggcgaa ttggttgaga aaaagaccaa tcagagcaaa aataagaaga
     5281 gacagcaaac tctttctatc ctttaaaaag accagtattt tatcctttgc agtagcataa
     5341 gccaagagca tgagaattcc accagcgatt aaaagacgca agttagtcaa gaccagagcc
     5401 gaaattccgt gtgccattag gtattggcca ctcgttcctg acaaccccca agcaatacca
     5461 gccacaactg ttagtaaagt cccttttaaa ctatttgaca tgtctctcct tactcttctt
     5521 tgcgaatcaa gttcatcact tgattgcggt ctaatatcca ttgagctctc tcgtcctttt
     5581 cataggtacg attcgatagg aaaatagtgg cttcttgctt ctgacgattc cacatgataa
     5641 aggtacctgt atagcccgta tggtctagcc aatctccttc caaattccat gctaaagaac
     5701 gttccttgtc atccaaagga gaaaaatttt gatttaagtc tcttgcaaaa tcatctgcta
     5761 aatagtgttc taaaaagatt tgtaaatcct ttatagtcga aaataaacca gcactcccag
     5821 catgtctacc caggaaacga gccttgggat catgcactat gcctgcctct acacctctaa
     5881 ctgttggaac agcaagctca actggcccaa acttagtttc cgtcattccc caaggtttcc
     5941 agacttgatc ctttaaaatc acatccaaat cttgattaaa aattctttcc aaaataaagc
     6001 ccaacagcaa aaaatggaca tccgaataaa gaaaggctgg ctgacttcgt ctgttgagat
     6061 gaaacatcgc ttcctttaat tcaggggctg ttaaaagatc acgattagga ataaaaggat
     6121 caaggtctgt tgcatgagtc aagagctggc gaatagtgat gtctggataa tcactctcag
     6181 gtaaaaaatc tattaccagt ctatcaatat ctaattgacc tatttcccac aagaaggtac
     6241 aaactgtgcc aaccccaaca accttgctga cactagctag gtcataaact agtcctgcct
     6301 cagtctgcaa gccatgctct ggggcactct ggcctaaata gaactctgtc cattgattgt
     6361 ccttaaaata cgcaaaagag gctccgggat aaattcctgc ctcgatttgt tcttctattt
     6421 ttttaataat cttggtccac ttcatacttc ttcaaaccac aattcaacat tatttctatc
     6481 tttaccaagg aagaattttt cagacttagg aataaaatat tcagtagact caaacttctg
     6541 gcgaagactt gctatgtcta attcattgac caagaacttg agcatagata agtcccaggt
     6601 aaccgtattg tccacagtca aatcctgccc ctgagctgga ataaaatcaa gggatgcccc
     6661 aatttcagat gattccaaga aactttcgat atcagttggg agatgtaatt ccatagaaat
     6721 ctcaaattta cttaaagaaa ttgatgccaa atctgtttga aattcaggct tttctcctac
     6781 ttctactaga cttgctctgt catcttccgc atgaatcaaa atcaaatcat cttctggtga
     6841 gaaaatttca aaagcgtagc cattttgacc tttatataat cgatgaatcg aatctgtttt
     6901 agataagatt ccttcaattt ctaagggatt ttccaccttg acaatcaatc tagctagttt
     6961 ttttcttccc tctaccttac gagtacgcat actgggagct tcttctaaaa ccagcttttc
     7021 aagacccgtt tggtcaccta gtgacagaaa ggccgattct tctaacaggg ccttcattcc
     7081 aagggtttca atataaaatg tttcatttaa ttttctatta ttagctttta aagtaggaat
     7141 aatccgtaca atctgattta cattcataaa ttcctccgtc actttttatt ttaaaggatt
     7201 ttagaatttt ttacaagata ttatgctcaa atttaacatt atttagctat ttagtaaaga
     7261 tagtctttca aggcttttga caaagcctga taaccagcaa tactgaggtg cagtccatca
     7321 gttgtatatt cttttttgag ttggcctgct tggtctgtca aacaatcaaa tactggcaca
     7381 aattccacct gcatataggc agatgcaagc tcttgatagg cttgattcca attctgaatt
     7441 ttttcattcg agcggatata gactgcctgc tggtacttct ctccctcatt gacaggcaaa
     7501 atggaaagca atttaatctc tgtcaatgga taatcgcgag caacggattg aatgatagct
     7561 tcgagattat tgagagcctc attcacagga acatcctttc cgatatcatt tgtcccaatc
     7621 agaagaaaaa ttttatctac tgctccacca tatagatgag catcaaggtt ctctagtaac
     7681 agtcctgtct gatagccacg aattcctcga ttgacaatcg tctttgaagt cccaaatagc
     7741 tcctgtagag gataatactc gacaatggaa tccccaataa aaagaatgtt tggttctaca
     7801 acagaaatgt gatttaggtg acgatatttg gtttgaattt tttcttgttc ctttaggagc
     7861 caattttcta ataactgtac tgccacttca ttctcctttt tctaaccagt tttccaagac
     7921 ttgataaact cctccttggc tgttggctgg tgctagagca gtcgccacag ctttggcttt
     7981 ctcatcagca ttttccatcg cataggcaat tccagccatt tcaagcattt caacatcatt
     8041 ttcactatca ccaaaagcca tgatttcttg ggatttcaag tcccagcgct tgagtaattc
     8101 ctccaagccc catgctttat gaatcccagc ttggaggata tcaatgcaac catagccact
     8161 ggatacagct cggacacggc catcaaagag agcattgatt tcttccaaaa ccgaactcaa
     8221 acgttcctca ccaacaacca tgctcatctt gagcacacca ccaaagaggt cagatgttaa
     8281 ttcatccaca aattgcatcc gttggtagaa tttttcaatc atttctggag tcataaaact
     8341 ttcaagatct gtaaaaatcg taccttcctt gacaaaatca cccttcatcc ccgttacaac
     8401 aaactggtcc tgacacgctc gacccttgaa atgagccaaa gccttgttga caatggcgtc
     8461 atcccatgtc tgagcctgaa tcaattcatt gttttcaaaa atacgagcgc cattagcaac
     8521 aaccagaacc actcgatcca ccaagggact cagtagttgt ctcatgcggt gaatttcatt
     8581 gcccgtcgca atgacaaaac gaatgcccct ttgatccaac tgatctaaaa tcttttccaa
     8641 tcgtgggaga tcaagctgac ctctagcatc cagcaaggtc ccatccatat ctgtcgcaat
     8701 taccttaatc atcatttact ttcctctgga ttcaagctaa taccacttca atcccacatg
     8761 ttcattcatt tctttatagg ctgtatcaat tcgttcctta gtcgcttcat ctaactggtc
     8821 acgatgactg ccatcctcta taaaatcttc caaaatataa gtttggtaat gatacaaggg
     8881 atatccttct ggtgaaaagg ttccctttgg tgttcgattg acccaagtag gatgagcttt
     8941 agctgttccg atagttgttt ttccatcctt cttcttgatg gtgacatcca tgagaacacc
     9001 acgttcagtc cacttagcat tctcttcatc tcccatagat tcaatccgtt gattggaaat
     9061 gaagttcccc atttaataga taatgagttt cttatctcca tctttttcaa ccgtttcaga
     9121 tggttcaaca acgtgaggat gccctccaaa gataatatcc gctccccaat cgatcatctt
     9181 gtgataaaga gctttttgtt cttcagttag ttccaatcga tactcaacac ccatctgaag
     9241 catgataatg gtgatatctg cttccttctc tgcccgttca atttcaacct tcatcttatc
     9301 ttcgtttaaa tctgaaagat aacgattata gtcttcctga gaaatatact gctcaattcc
     9361 attgaaacca taggaatagg ctaacaatgc aaccttgata ccattcactt ccttaatgac
     9421 cagcggagcc tgatcacgtg gttcgtgcgt ataaactccg attggagtga ttccagcttt
     9481 ctcaataata tcggccgttg aaataactcc ctcaatttgc gaatccaaaa tatgattatg
     9541 agctaaatcc agcacatgat aacctgcctc cttaatagca tccataactt cagcaggagc
     9601 attaaagaga agataacccg ctaaataatg atccttatta atggttcctt caaaatcacc
     9661 aatagctaaa tctgctgctt agtccccttg cttgagccaa ggagtcacat actcaaaatt
     9721 ttcatgaaag tcataggtac cgtcttcttt tttagctgaa aagaaaagtc catcgtggta
     9781 gagcaaatcc ccgtgggcca taattctggc agttttttcc tcttcctact cctgagactt
     9841 ttgcttagtc ccctcttgag aaatagtatc tcgtttttga ctagtcaagg gattccttgg
     9901 aagctttcaa acaacaagac caagcccatt gataaatcaa ctgctagcaa gagtatcgcc
     9961 acaaatccct tattgctcca cttgcgataa ctcctaaaaa gtttaccaag cccttcataa
    10021 aacgaaaagc taaaccaccc tgatttcgat tttgtcttct ttgtatcttc attctcccta
    10081 ctttcttatg caagcctttt ctttttatta tatcacagat aagtatttct ttcacaattg
    10141 aattgaactt cccatctatt ttctataaat cctaaatgcc ataatgcttt caattcttgt
    10201 cattttgtga tatcatgtag aggaaatgaa ctaatccaca gtggcttatt ccaagtatac
    10261 cacttgggct ttggcagtag ctaactgcac taaacataat ataaggagag aaaatgtctg
    10321 caatagaacg tattacaaaa gctgctcact taattgatat gaacgatatt atccgtgaag
    10381 ggaatcctac tctacgcgcg attgctgagg aagtcacttt ccccctatct gaccaggaaa
    10441 tcatcctagg cgaaaagatg atgcaattcc ttaaacattc ccaagatcct gtcatggctg
    10501 aaaaaatggg actccgcggt ggtgttggac tggctgctcc ccagttagat atctcaaaac
    10561 gcattatcgc tgttttggta cctaatattg ttgaagaagg cgaaactcca caggaagcct
    10621 acgatttgga agccattatg tacaatccaa aaatcgtctc tcactctgtt caagatgctg
    10681 ctcttggcga aggagaaggt tgcctgtctg ttgaccgtaa cgtgcctggc tatgttgttc
    10741 gccatgcccg cgttactgtt gactactttg acaaagatgg agaaaaacac cgtatcaaac
    10801 tcaaaggcta caactccatt gttgttcagc atgaaattga ccacattaac ggtatcatgt
    10861 tttacgatcg catcaatgaa aaagacccat ttgcagttaa agatggttta ctgattcttg
    10921 aataaagaaa atcccgttgc aagacggggt tttgtgttat aatagaggca tgaaaacaaa
    10981 tgatattgtc tatggcgtcc acgccgttac cgaagccctc cttgcaaata caggaaacaa
    11041 actctacctc caagaagatc tccgaggtaa gaatgttgag aaagtcaagg aactagctac
    11101 agaaaagaag gtgtccattt cttggacatc aaaaaaatct ctctctgaga tgactgaagg
    11161 tgctgttcat caaggttttg ttctacgagt gtctgaattt gcctatagcg agctagatta
    11221 catccttgca aaaacacgcc aagaagaaaa tccacttcta ttgattctag atggtctaac
    11281 cgatccccat aatctgggtt ctatcttgcg aacagccgat gcgaccaatg tttcaggtgt
    11341 catcattccc aagcaccgtg ctgtcggagt aactcctgtc gttgccaaaa cagccacagg
    11401 tgctattgaa cacgttccaa ttgcccgagt gaccaacctc agtcaaacct tagataaact
    11461 caaggatgaa ggcttctgga cctttggaac ggatatgaac ggtactcctt gccacaagtg
    11521 gaatacaaaa gggaaaatcg ccctcatcat cggaaatgaa ggaaaaggca tctctagcaa
    11581 catcaaaaaa caggtcgatg aaatgattac cattccgatg aatggacatg ttcaaagcct
    11641 caatgccagt gttgctgcag ccattctcat gtacgaagtt tttctaaata gactataaaa
    11701 aagtttccag tcatctgatt ggaaactttt ttatgattaa ctatgttctg tgataaactt
    11761 gtaggcttct tgaccagcga tagctccatc tccaactgct gttgttactt ggcgaaggtc
    11821 tttcaagcga acatctccaa ctgcaaagat accgtcgact gcagtcttca tgtggctatc
    11881 tgtcacaatc cagcctgcct gatcttggat attcaattct ttaacaaaat cgctaagagg
    11941 gtccaaacca acatagataa agacaccacc gaaggcttgc tctgtcactt gacctgtttt
    12001 cacattttca aaaacgacag attctactct gttttcaccc ttgatttcct tcactacaga
    12061 atcccagata aagctgattt tttcattcgc aaaggcgcga tcttgtaaaa ccttttgggc
    12121 acgaagttgg tcacgacggt gaacaatggt aacagtctta gcaaaacgag tcaagaagag
    12181 ggcttcttca acagctgaat ctccaccacc aactaccaat aaatcttggt cacggaagaa
    12241 agcaccatca cacacagcac agtaagaaac accacgactg ttcagttctt cttctccagg
    12301 cactcccaaa ggacggtgtt tagaaccagt tgctacgata actgtacgtg tttcatatgt
    12361 ttggtcatca gtcatcactt tcttaaaatc accatggtct tcgacatttt caacataacc
    12421 ataaatgtgc tcaacaccaa gattttcaag tggttcaaac atcttttcag ccaattcagg
    12481 tccactaata ttagcatatc ctgggtaatt ttcgatatca gatgtattat tcatctgacc
    12541 acctggcaga ccaccttcaa tcaaagctac ttttagattg cttcgagcag catacaaggc
    12601 cgcagtcatc cctgcaggtc cagcaccgat aataatagta tcgtacatat agattccttc
    12661 tttcttgttg taactatctt tattctaact ctttcttgtc aatcacgcaa ggattatgcc
    12721 ttgaaaacaa gaattaaact cataaccgca aaggataata ctgggacaac caagactcca
    12781 atcataatca tatcatagag atgggcttgg cgagccccgg ctgtcttatc aactcccgac
    12841 atggctctca gaccaatcca aatccctaaa aaaatcagaa caaggatggt ggtcaagatc
    12901 aaactctcga aatataaaga aaatagttgc agtagcatga tttctctcat ttctatcttt
    12961 tttaaagagt aaactcagct agtccaacta actgagtttt cctttatcta ttatatcaaa
    13021 tataagtccg tttgtaacta gcaaagaatt cttttgtccg ctcttcttta ggggtgtgga
    13081 taatctcatc cggagttcca gactcgatga ttttcccctt atctaagaag agaattttat
    13141 ccgcaacttg ggctacaaag gacatgtcat gactgaccaa aatcatggtc tgacctgact
    13201 tagcagcatc tgcaatagac ttttctactt caccgaccaa ttctgggtca agggctgaag
    13261 ttggttcgtc taagagcaaa acatctggtt tcatagcaag cgcacgcgct agggcaaccc
    13321 gttgcttctg tccacctgat aaatggcgag gataatggtt ttcacggtcc gaaagcccaa
    13381 ccttagccaa ctcttccttg gcaatcttag tcgcttcttg gtcagataat ttcttgacaa
    13441 caaccaagcc ttctttcaca ttatcaagtg ctgttcggcg ttcaaataaa ttaaactgtt
    13501 ggaaaaccat agacaactta cggcgtaggg caaggatttc ttcttgagtg attttagaaa
    13561 aatcaactga aaaaccatca atctgaatag agccactgtc aggtgtttca agataattga
    13621 gactgcgaag aaaggttgat tttccagctc ctgaagaacc aatcaaggct acaacttccc
    13681 ctttttgaat atccaagttc agatgatcca agacagtctg tcctgaaaag gatttgctta
    13741 aattcgaaat cttaatcatt aacgaaggtc tcctttcaca tctgtttgca ctgtatcagg
    13801 tgcagaaata gccatttttc tctcgatgaa acgaccgagg ctttcaattc cgatattgac
    13861 tacccaataa acaagggcaa cggagatgaa gcgttcaaaa tagcgataat cagctccacc
    13921 tagaatctga gcttgggcaa agacttccac aacacccgca ctaaaagcta gagatgttcc
    13981 cttggtcaaa ccgatgaggg aattaatcaa ggttggagta gctaccaccg ctgcattagg
    14041 aataatcact cgtcgataaa cttgcgctcg ggtcataccc agactgcgcg ccgcctcaat
    14101 ctcaccagga ttaactgaga gaatggctgc acgaatggtt tcactagcat aagctgcctc
    14161 attaaaggca aaagcgacaa tcgcaaaagc tgcagctgga atcgcattga tattgagacc
    14221 agttccccat tgctgattga gggctttcaa agccaaaggg attccgtagt aggtcaacat
    14281 gagttgcacc aaaatcggtg tcccttttaa gaaactaaca aagaaggcct gcaagggata
    14341 taaaatcttg acacgattga tcttcacaat ggcaaaaaga agcgccaaaa ccaagccaaa
    14401 aagggcacca ccaattgtca acataattgt tgttggaagt tgttggacaa ttctagggat
    14461 tccatcaaag accgaacgta ggctaaacag cttgccatcc ggaatcaatt gcatcaagtt
    14521 ttggtaccaa tctgatgcta aaatcgttgt aacattcata aaaacatcct cttctgataa
    14581 tgattcattc taccatgctt ctgccgtcaa tgaaattatt tgctacggtc agatacagac
    14641 tttgtctacc tactagttta tcatactttg aaacagggaa gttatatatt ttatctatca
    14701 aagagataga taaaaactat ttcagtccca gttcttcata agattttcga taaccgattt
    14761 gcttaacagt tccattttct actaaaatgg gccgttttaa caacataccg tcacttgcta
    14821 gcaactcagc cgcttcttgg tttgacaaac ttcctacctt atcttttagc cctaattcac
    14881 ggtatttgat accactggtg ttgaaaaatt gcttcaattc aaatcctgag gtttctagcc
    14941 aattcaaaat gacttcttgg ctaggtgttt cttccacgat atggacggct ttataatcca
    15001 cacttaattg atttaattct tgttttgctt ttttacaagt tgaacatttg gggtattcga
    15061 taaattctaa catgtgcttc tccttctatt tgtttatatc tttaaaatct acgccttcat
    15121 gctccaagag ccaagctttc ttttccactc ctgcagcata gcctgtcaga cgcttgcctg
    15181 ctcccaacac acgatgacaa ggtactagga tagaccaagg attgcgtccc actgctccac
    15241 caattgcttg agcagaagcc acttgcaggt cttgagcaat ttgtccatag gtcactgtct
    15301 gaccataagg aatgccctgt aaatagtccc aaactctctt ttcaaaattc gttccgattg
    15361 gcgccaagag caagttggat aaatcctgag gcttgccttt aaagtaatca tctaagcaag
    15421 caataactgg gtctaaaata ggatgactaa caacttcttc tatcgtttca tctcctagtc
    15481 ccctctcaaa atgcttctgc tcctgaaccc aaattccata caaataatgg tcatcagcta
    15541 caagtgatag aataccaatt ggtgaggagt agagtatttt tacatacttc ttttgcatta
    15601 tttctttaat ttttgatagg ccaagcgttc gccatctact ggcaccttac caacttgttt
    15661 aaaaccaagt ttttcaaaaa tatgttgcat aaccttgttt tcagcatgcg tatctgagcg
    15721 aaaatcaaga taatcaaaac cttcaatcaa gccctctaag aaggtttgag caactccttt
    15781 tccctgcaca tctgctgcca cagcaatacg gtgaaagact agatactctg actctccagc
    15841 ttgccagttt ccctcataaa tagcttcata ggcctcctct ggactcttgg tcacagcagc
    15901 ataggctagc agttctccct cttccaaggc tacgtaggct tgccctgaga tgatatcatc
    15961 gataataaca tctgcatttg gatagccatt ttgccactgg tcactaccag catctgctaa
    16021 acattttttg gcatcctcca tcacctgcat gatggcatct acttcatttg gaaaagctaa
    16081 acgaatttcc atcttttttc ctcatttctg actagtttct cccatcatag cataatttaa
    16141 gtatttctac aagcagttaa aacttgactt tgtgtttttg ttattttata atctagttat
    16201 caaaactata taaaaaggag ttgaaaatga aaactacctt ttcctaccca aaatgggcag
    16261 aaattccaaa cattgacctc tatctggacc aggttttgct ctatgtcaat caggtctgcg
    16321 cccctatctc tcctaataaa gacaagggcc taacagcatc tatgatcaac aattatgtga
    16381 aaaatggtta cctgacaaag cctgacaaaa aaaaatacca acgccaacag attgcccgtt
    16441 tgattgctat cacaaccctc aagtctgtat tttctattca agaaatagcc cagacactta
    16501 atactctaca aactcaagca agttcagacc aactctacga tgcttttgtg gactacatga
    16561 accaaggaat tgacccagct aaccctatta tccaaaccag ctgccaaacc gttaaactct
    16621 atcatcaaac tctagactta atcgatcata ctcaagagga ggtaatccaa tgaacactag
    16681 tcttaaactc agcaaacaac tcagttttgg agaggagatt gctaatagcg tgacccatgc
    16741 tgtgggtgca gtcatcatgc ttatcttgct gcctatttca tccatctata gttatgaagc
    16801 acacggattt ttatcctcta tcggcgtttc cattttcgtc atcagtctct ttctcatgtt
    16861 cctatcatcc accatttatc actctatggc ctatggttcg acccacaaat atgttttgcg
    16921 aatcattgac cattctatga tttacgttgc cattgccggc tcatacacgc ccgttgtctt
    16981 gaccttgatg aataactggt ttggctatct gattattgtc atccaatggg gaacgaccat
    17041 ctttggtatt ctctataaaa tctttgctaa aaatgtcaat gagaaattta gccttgctct
    17101 ttacctgatt atgggctggt tggttctggc tatcattcct gccattatca gtcaaacgac
    17161 acccgttttc tggagtctca tggtaactgg cggactctgt tatacagttg gagctggatt
    17221 ttatgccaag aaaaaacctt atttccacat gatttggcat ctctttatcc tagctgcgtc
    17281 cgtacttcaa tacatcgcta ttgtttatta catgtaaaaa agttgagaaa ttcaatctca
    17341 acttttttct ttacacatat tgataaagta ctggtgcaag cgcacatcat cagtcaattc
    17401 tggatgaaaa gaacttacca acatattttt ttcttgggct gcaacaattt gattgttcac
    17461 tgttgctaga atttctacac cctcaccaac actactgata atcggaccac ggataaaggt
    17521 cattggaatc ttgccaactc ccttacattc tgcttccgtg tagaaacttc ctaattggcg
    17581 cccataagca ttacgctcga ccaccatatc catagttcct agataactct ctttctgaga
    17641 agtgatttcc ttagccagca aaattaagcc cgcacaggtc ccaaacactg gtaagccaga
    17701 tagaatggct tctcggatga gaagtagcat gttctggtca cgtaagagct tgcccatggt
    17761 tgtagactca ccaccaggca aaatcaaacc cgacaagtca ctctgatctt gctgaaaatc
    17821 atctagattt ctgagttcta cactctcgac acctaattga tctagcactt ttgcatgttc
    17881 tgcaaaggcc ccttgcaagg ccaatattcc gattttcatc tattttcctc gttcagccat
    17941 gagaatttgg atttcatttt cattaatacc aaccatggct tctcctaaat cttcagagat
    18001 ttgagctagg atttgaggat tacggaagtt agtcacagcc ttaacaatgg cactcgctcg
    18061 tttaacagga tctcctgact tgaaaatacc tgaaccgaca aagaccccct ctgcccctag
    18121 ttgcatcatt aacgcagcat ctgctggcgt tgcaacacct ccagcagcga aatttacaac
    18181 tggcaatttt ccatgttcat gaacatattg gaccaattct acagggactt gcaaatcctt
    18241 ggcagcaaca taaagctcgt cctcacgtaa gttttgaatg cggcgaattt cctgattcat
    18301 catacgcata tgacgaacag cttggacgat atcccctgtc cctggttctc ctttggtacg
    18361 aatcatggaa gcaccttcag cgatacgacg caaggcttca cccaaatcct tagcaccaca
    18421 gacaaaagga acttggaatt ctttcttgtc cacatggaaa cggtcatcag ctggagatag
    18481 aacttcactc tcgtcgatat aatcaatttc aatagcctct aaaatctgag cttcaacaaa
    18541 atgcccgatt ctgaccttag ccattactgg aatactaacc gcttcttgga tttccttaat
    18601 catctttggg tcgctcatgc gggaaactcc tccagctgca cgaatatcag ccggaattcg
    18661 ttccaaggcc atcacagctg ccgcaccagc agcttctgcg atacgagcct gttcaggatt
    18721 ctgcacatcc ataataacac cacccttgag catctgtgcc aagtttttat ttagttcata
    18781 acgattttca gtcatttgtt ttatcctcat catttgtatt ggtagctacc ttttcatttt
    18841 aagtcagaac agaatgaagc acaagataaa aaaactataa ttgtatgggg acaaattagc
    18901 taaaaactat ctgaccttaa cttaaggcca gatagctcat tcatttttat ttttcagccg
    18961 taagggcagc cattgtgatg tagttgtatg gtttgttgaa gtgtggcaag aagaagaggt
    19021 ctgtcaatgc caatttatca attgtcacat gctcttggat agcaagtgag aacatgtgga
    19081 ttcccatgct aattgcaata tcatgtgaaa ccatttgggc accaagaatt tcacggctat
    19141 ctttgtcaaa gacaatctta attgctactt catggttgtc atgtttcatg aattctggtt
    19201 tttgaagatc gttaaagcct gtttcagttg cgttgtaacc agcagctttc gctttttcaa
    19261 gagtcaaacc agttgaaacc atgtgaagac cgtagattga gataccattt gaaccttgaa
    19321 caccgattcc ttccaattca tgtccacaag cattgtaggc accaacgata ccagtgcgaa
    19381 cagcatttga agcaagagcg atatagcttg tatctttacg agcattgtca taaacagtcg
    19441 cacagtcacc aacagcgtaa acgcctggga tagatgtttc ttgtttcttg tctacaagga
    19501 aggcaccgtt gcggaagagt tcgatcttac catctgcaag ggctgtgttt ggacggaaac
    19561 caactgcaag gataaccata tccacgtcaa agctttcttt gtcagtaatc aagcgttcaa
    19621 ctttaccgtc accttcgatt gctttaacag tttgacctag agccaagcgg atgttgtgat
    19681 cttccaagtt cttcgccatc atttgtgtga agtctttgtc atagtaaccg ttcaagacag
    19741 tatcaacgat atcaacaagg acaacttctt ttccaagacg ttcaaaggct tcagcaagtt
    19801 caacaccgat gtaaccacca ccaacaacgg cgatacggtc gaggtgttgg ctcttgtcag
    19861 aaagtttatt gataacttct tcagcatttt ggtacaattt cacgaattgt acgttttcaa
    19921 gagttgcttt aaattcgcgg tttcctttaa caatttcaac accttcgatt ggtggcaaga
    19981 ttggtgtaga acctgtagcg aaaatcaatt tttcgtatga ttctttgtgc tcttttcctt
    20041 caacttccgc tgtaactact ttgttatcat agtcgattga aagaacaggt gagttcatgt
    20101 aaactttagc acctttagct tccaattttt ctttatcaga atagaacaag ccttcagcac
    20161 cgtcaatttg ttcaccaatc caaagagcca ttccacatcc taggaaagag atgttagagt
    20221 tttggtcaaa tacaacaatt tcgttctcat ttccaaaatt atccaacatg gtattgatac
    20281 atgctgtacc agcgtggtta gcaccgacta caacgatttt actcataaaa atttcctgcc
    20341 ttcattctaa atttacctta ctagtatacc atttaccgtt agcgtttaca aggggggtac
    20401 tattatttca gcatttttta tcaaaaataa ttccccattt atcctgtttt caagcctcat
    20461 gaattttatg agcatatttc ttgacttttt ccaaattttg tttgtgaaaa ttctaacttt
    20521 atggtattat aataacatga aaatgaaatg taagggcttc aatttagatg attatttgat
    20581 attacaactt attttctata agagaaagga gttggtagct tgactcttcg ttcacattct
    20641 gaacggctaa tggggactac tatcactatt tcattagtgg atgagcaagc cgatatcttt
    20701 ctccaaaaat cctttgactt gctcaaagag cttgaatacc gcttcaacgc caatagtcaa
    20761 gaatctgagt tgatggaaat caattatcaa gcaggaatat cccccgtcac ggttcatcca
    20821 gacctgtttg agctgatttc acttgggtta gagcatagcc tagcgctctc tagccacctc
    20881 aatatcagca ttggtccctt aattcaaacc tggcgtatcg gtttttcaga tgccaaggtc
    20941 gcccagcctc aagaaattga atcggtgctg cctctaatca atcctcatgg tatcgagtta
    21001 gattcttcta cttctactgt gtttttaaaa cagaaaggaa tgaagatcga tctaggttgt
    21061 ttagccaaag gatacagtgc ggataaggtt gcccaatttc ttaggaaaga gggggtgact
    21121 tctgccttga tcaatctggg agggaatatc ctgaccattg gaaaaaatca ggcaagaggg
    21181 gataacccat ggcaaatcgg gattcaagac ccagccaatc cgaggggaaa tcatttaatg
    21241 accatccctg ttgtcaataa atctgtcgtg acttcaggca tttatgaacg tcacctgacc
    21301 gtcgatggac aagattacca tcacattttt gacagtcaaa caggatatcc tgttgaaacg
    21361 gaactagcga gtctaacaat catctctgat aaatcagtcg atggcgaaat ctggacgact
    21421 cgactctttg gagaaagacc tgcttctatc ttctggcaag tcgaaagttt ggagggcatc
    21481 gaagtcatcc tcatcgataa agaaggccac ctaagctgtt cttcaggaat tcctactcta
    21541 tagagacaac tgtttcaatg gaattttaaa attgtattat gtaaaaagag aaaggaaatc
    21601 tcatgttaaa acttattgct attgttggaa caaattcaaa acgttctaca aaccgtcaat
    21661 tgcttcaata catgcaaaaa cactttgctg acaaagctga aattgagctt gttgaaatca
    21721 aggccattcc tgtcttcaac aaaccagctg acaagcaagt acctgctgaa atattggaaa
    21781 ttgctgctaa aatcgaagag gcagatggcg ttattatcgg tactcctgag tatgatcact
    21841 ctattccagc tgttttgatg agcgctcttg cttggttgtc ttatggtatt tacccacttt
    21901 tgaacaaacc aatcatgatt acaggtgctt cttacggtac gcttggttca tctcgtgccc
    21961 aattgcaact tcgtcaaatc ttgaatgctc ctgaaatcaa ggcaaatgtt cttccagatg
    22021 aattcttgct ctcacactct cttcaagcat ttaacccaag tggcgacttg gttgaccttg
    22081 atgttatcaa gaaattggat gccatctttg atgacttccg tatctttgta aaaatcacag
    22141 aaaaattacg taatgcacaa gaattacttc gcaaagatgc tgaagacttt gactgggaaa
    22201 atttgtaaga taggagacca aaaagaatga aatttgttgg acttgttgga tcaaactacg
    22261 atcaatcata taaccgtaag ctcttggaat ttatccgtcg ctacttcaaa ctcaaatttg
    22321 aattagaagt tcttgaaatt gacgaagttc caatgtttaa ccaagatgaa aaatgggatg
    22381 aaagtttcca attacgttat ttatataaca aaattactcg tgcagatggt gttatcattg
    22441 ctactcctga gcataaccac actatctcag cttcactcaa atctgtactt gaatggcttt
    22501 catacgaagt tcatccattt gaaaacaagc ctgttatgat tgtgggtgca tcatactatg
    22561 accaaggaac atcacgtgct caagttcacc ttcgtaaaat ccttgatgct ccaggtgtta
    22621 atgcctacac gcttccaggt aacgaattcc ttcttggtaa agctaaggaa gcttttgata
    22681 acaacggaaa tatcaccaac gaaggcactg ttaaattcct tgaaacttgc ttagataact
    22741 ttgttaaata cgtaggagtc gtttcgaaat tgaaaaaacc aaaaccaatc gaatcagaag
    22801 acttggattg tggaaaacca atcgctacaa ccatcacaga agttgaccct gacgatccag
    22861 aatgggtaga aaaagttgca gcaatcactg gtgctgtttc tggtgatacc tatgtcaaat
    22921 tggaccacgg tatcctaaca gttaaccaaa ttgatatgtt cttgaaagct atgccatttg
    22981 aattgacata cgctgacgac aacaaccaat tcctctacta caacaacgct caccaagatc
    23041 cagacactat gttcgctaaa cgtgtaccac ctcaatcagg tagccgtatg tcgactgttc
    23101 atggttctct tccaccagca cgtatgaaga acgtagagtg ggttatcgga acacttcgca
    23161 acggaaacca agaatacgtc cgtacgatcg ttccaggttc tcctgcaggt gttatcaaca
    23221 ctcacaacta ccaagcaatg tactatcctg atggatcata cgctggtatc aatgaaatcg
    23281 tctttaactt ccaaccatgg cttgactggt acctaaaaga gactggtcaa cgtttggtgg
    23341 gtggtagcgg accatttgct cctgctgccg gaggtcatgg agacgccgat gctacttctg
    23401 gcgcttctga ttcaggggat gctggaggcc acggtggtga cgcagacgct acagccggtg
    23461 caagttacta atgatagttt ttaggaacca ttatggttcc tttttagcga aaaaagacta
    23521 gcaaacacaa actgctagtc tctttgttat cgtttcatct atctttgtta aaagaaagaa
    23581 tacatattat gaatttggat catcaagact acggccatgt aatccttttt cacgttgtac
    23641 ttggcgtagt ttttctggtg taacatcgtt tccttcttcg tccacaattt tgattccttc
    23701 aatgtggtga cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta gtttggcttg
    23761 ttccactttt tcttctggtg ttaagccttc tgtttttttc tttttagcaa gctcattgat
    23821 acgagcaatt tttttcggat ccatttcttc tcctctgtaa taagataaag tccgtttatc
    23881 aaattttatt tagtgttaat ttggttaaaa caagcaaact tagctgcttt cttggttagt
    23941 tgtgacaaga ttgccaaacg attttgacgg acagcctgat cttcagccat taccatagta
    24001 ttttcaaaga aagcatcaat gactgggcta agcgcaaaga gttgtttcaa ttgctgactt
    24061 gcaggtcctg ataaaacgag tgtttctact gcttctgcca aagctttttc ttggtcattc
    24121 tcaaatagtg ctgaatcaac tgtagcaacc ccttctgcct tctcagccag gttaaaggca
    24181 cgagaaagtg attcaacaga tggtttaaaa tcttcttcct tgcttacttc tacgagagca
    24241 cttgctgctt ccaacatatc tgccacaaca aagtttgaac ctgcaagaac tgcttccttg
    24301 atatcttttg gagtagagcc catcatctta tcaacacgag ccttgataaa gtccataacc
    24361 tctgctttat tttcataagt caaactgtca aatttcaatg cataaaggct atcaatcagc
    24421 tcatccatag caatgtgcca accaaaggca tccaagatac gaaccacacc ttgagttgca
    24481 cgacgaaggg cataagggtc attagaacct gatggaatca atcctactga gaagaaactc
    24541 aaaatcgtat ccaatttgtc tgcaatggct agaactgcac cgaccttgct ctctggaagt
    24601 tctccttcag ctgatgtagg catgtagtgt tcacgaatag cagctgccac cgctggagtt
    24661 tcaccagcaa gaagggtgta tttttcaccc ataattcctt ggagttcgtc aaattcacca
    24721 accatacctg tcaacaagtc aaacttgtaa atggctgctg cacgagcaag gtcaactgtt
    24781 tcatccactg acaaaccagc tttttctgcc aaaagtacag tgatttgacc cgtacgaatc
    24841 atgtgttcac gaagggaacc aatcttctca tggaaggtga cattgtttaa tttttcaaca
    24901 agatctgaaa tcaccaattt ttggtcttca cgccagaaga attctccgtc ttccaagcgg
    24961 gctaccaaga ctttttcatt tcctttgatg acatttttca aacgctctgc gtttccgtta
    25021 cgaacagaaa tgaagtttgg caagagtttt ccatcttgat cacgaacaac aaagtaacgc
    25081 tggtgttcct tcatagaagt caccaagact tcttctggaa cttcaaggta tttagcatca
    25141 aaacttccca tgaaggcagt tgggtattca accaaattca agacttcatt cagcaaatcc
    25201 gcatcaattt cgatacgtac accatgtttt gcctcaattt tcttgatttg gtcaacaatc
    25261 atttgctcac gttcacatgg atctgcgatt acaaactgct tacgaaggtc ttcttcatag
    25321 ctcaatgctg actgaatttt ggtttctttc cccaagaaac gatggccacg gctcacacga
    25381 cctcccttga tatcaaggaa atccaagtca aactcttgct catccaagag aacagttaaa
    25441 gtgtgaacag ggcggatgta ttcaaagcta tttccagccc agtgcatgct gacagggaaa
    25501 gtcaatgact tcaagacatc tacaacacca ggaacaatgg cttcaactgc ttgaccaact
    25561 tcttccttag tgacatagac atattcttca cccttgattt cacggaattc gatatcttca
    25621 acagtcaagc cttttccacg gacaaatcct tgagctgctt tggtgaagtt tccatcacta
    25681 tccaaggcaa tttcctttgc tggtcccttg aaatcttctg tcaaatcaga ctgtttgtct
    25741 gataaaccag tcacacgaac agccaaacga cgtggtgttg agaaggtttg aatggcttca
    25801 aaagacaggc ggttttcctt gaggaaggct gccatttttt cgcctagttg tttttcactt
    25861 ggtgtgacaa cataggctgg taattcttca agaccgagtt ctactaataa gttttttgtc
    25921 atgttttttc tccgaaaagt atctttttat tttccagttt gccttatgtg attggcacgc
    25981 aagcaaccaa cttcgttgtt tcattgctaa aattggagcc aaaagtctcc aattttgcct
    26041 agtatcctta gtttcactaa ggataccttc atcactgcgg caactgactc agggctcact
    26101 ctgttcgccc attttcgtaa tttgtcactc tctttattct gcgtcttctg ctaggagttt
    26161 agctcttgtt tcttcatcca aaagtgggta acctaggcgt ttgcgttctg caacaaaggt
    26221 tttggctaca acacgggcca agttacggat acgagcgata tagcctgcac gctctgttac
    26281 agatacagca ccacgcgcgt caagcagatt aaaggtatgt gaacatttga gaacatagtc
    26341 ataggcaggg tgtaccaagc cttcttctaa tgcacgacca gcttcttttt caaacttatc
    26401 aaagttttca agcaacattt cttggtccga aatttcaaat gaatattttg agtgctcata
    26461 ctcaggctgg ataaagattt ctccgtattt tacaccatca gcccactcga tatcatagac
    26521 agagtctact tcttgaatgt aagaagccaa gcgctccaaa ccataggtaa cttccgcagt
    26581 cacagggcca gttgccaatc caccgacttg ttggaaataa gtgaactgag tgatttccat
    26641 tccgtcaagc caaacttccc aaccaagacc agctgaacca gttgatgggt tttcccagtt
    26701 gtcctcaaca aaacgaatat cgtgctccaa aggattgatt cccaattttt ccaaagactc
    26761 aaggtaaagt tcttggatat ttgatggaga aggcttcatg accacctgga attggtggtg
    26821 ttggtagaga cggttagggt tttccccata acgaccgtca gcaggacgac gtgatggctc
    26881 tacataagct gcattccatg gctcaggtcc gatagcacga aggaaagtgt aaggactcat
    26941 tgttcccgca cctttttcat tatcataagc ctgcataagc atacaacctt ggtcattcca
    27001 aaattgttgc aaagtaagga tgatttcctg gaaagtcaat ttcttagaca ttgtttactc
    27061 ctttttatat aaattacttg cgacatgagt ctgcctcgtc gatcatacga ggcaagacga
    27121 gttagtactg cgtctagctc aggcactcta gtgctgagcg tggggcagtc cgactgtaag
    27181 gaggtttctg ccactgatgc agtaaaatgt taatttctta gacattgaat actccttaat
    27241 aaaaaatgat ttcttgcgac acgagtctgc ctcgtcgatt atacgaggca agacgagtta
    27301 gtactgcgtc tagctcagca ccctagtgct gagcgtgggg cagtccgact gtaaggaggt
    27361 ctctgccact gatgcagtga aatgttaatt tcttagacat tgtttactcc tttagttttt
    27421 atatttcttt ttcaattaat ttctgctgaa caaaccaatc taacaaggga aaaatttttt
    27481 ctgtatttgc ccataaatga taagaatcta agaccgcttg tacactacct aaattttcta
    27541 ccaacttatc tactgtcaaa aagcttcgcc agtattcata aaaaatactt gcatagttct
    27601 tatcataagt cgaagaacca aaatcattca atgaatgcca accatacttc ttctgaaaaa
    27661 gttctacgag agattgatta caaatttttt ccgcttgaaa ttcctcttct gtaaagaaat
    27721 acttgcgact aatatattca accatcccct cttcgaacca gatataagag tcataaccat
    27781 caaaatcatc taaaaaatgc tccgaccaat gagctaactc atgtcctaca atctgtaaga
    27841 ggaaattttc agataaagaa tgatagtgac tttctattgc ttgagtttgc tcagaacact
    27901 cgtagtccat caattgatac aaatacaact ctttccaaac agctaaatca ggcgccataa
    27961 ccattcgtct attatttgta taggctggaa cagcgctttc cctaataatc tgtgtagcag
    28021 cattaaaatc tgaccaaata acggcttgcg gtaaatcaca gactgcaagt tcattcttta
    28081 aaaaagattg ataatctttc aacttttcag tatttcttac tacaaaatca cgaaatgtag
    28141 ctagttgact atcgtctttt acaagataaa ggttgtccac ggctctcctt tctttcacac
    28201 aatagactga ataagcaaaa gaaccgcgtc cgacaatcct aggttgattt aacctagggg
    28261 cgtcagaaac gcggttccac cctaatttat tacttcattg tttttgaaaa tactacagaa
    28321 agcgccagct cattattttg ccctacttgg ctcccactat cccaagctcg cttgaagaac
    28381 gccataagac tttctttcct gctgactatt atatcaaaaa ttagaataat gtacaattct
    28441 ttttatgatt ttctagaaat ccacatcatc aactcgtgga gcacccgatt gaacagcaat
    28501 cgtttttaag gtttctctct cctcatgact cagttcaatt ccaaagcaat caagattagc
    28561 ttgaatacga gaggttgtga cagattttgg aagtggtaaa aatccttctg ccaagctcca
    28621 ggccaaggct atctgagcaa tcgattttcc gtgatttgct gcgatttctt gcacttgctt
    28681 gctatcaaat agttctccct gaccaaaagg cccccaagct tccaataaaa ttcccttttc
    28741 acgacagtaa gctacgactt gatcttgata cacacctggc gccaagcgaa cttgattgac
    28801 cgcaggaacg atagttgcag tttcaagcaa ggcatccaaa tgatggggaa gaaaattgct
    28861 aacgccgata gcacggattt tcccttcttg atagaggtct tccatcgctc tccaaacttc
    28921 cgcattgcga gttttccatg cgtcattttc tctgagcggt tttgggttcg gccaatgaat
    28981 caaatacaaa tccaaataat ccaagcccag tttttctata gatttttcca aagcttgacg
    29041 agtttgctca taggtttgct gactattcca aagcttggta gttacgaaca tttcttcacg
    29101 tggaactccg ctatctttga ttgcttgacc aacactttct tcattctgat aaatcgccgc
    29161 cgtatcaata tgacgataac cagccttcaa ggcttctaac actgcatgat aggcttcttc
    29221 tccatcctta gccttaaaag ttccaaatcc caatactgga atttctactc cattatttaa
    29281 ttgataggta ttcatatgct tctccttcta ttttattcat caattatagc ataagacatt
    29341 ttttaagtag tactatcttc tgtaaaaaat aagtctgtca aatatctaac agacctattt
    29401 tttcttgctt attcatcacg actatagtac agctcatgag cttttaggcg agtattgagc
    29461 atctctggta tggtcacaaa ggtataacct tgatttttca aatactcaat gacccttggc
    29521 aaggcattga ctgtcggact gtgaatatca tgcatcaaaa cgatagagcc gttagctact
    29581 tgatgctgaa tttctgtcaa aatagatgct tcatttttac tcttccagtc cagactatcc
    29641 acatcccaca tgataaagct caaatccaag ctattgcgaa tatcatctgt aatagcacca
    29701 taaggtggac gcatgagttt agaactagaa cccagcactt tagttagcac atcctcagta
    29761 tcagtaatct gctttttagc ttcatcaaga gagagttgcg agagaatcgg atggctccaa
    29821 ctatggtttc caacaacatg accttcagat tttatcctct tcaccaagtc ctcattccca
    29881 gaaacatttt tcccaagcac aaagaaagtc gctttaatat catatttagc tagggtctct
    29941 aatacctgcg gggtcgttgc tggatttgga ccatcatcaa aggttagagc gacaactttt
    30001 tgatatttct tatcaaagta agattgatac aaggccgcat ctttttcgag taagtacgaa
    30061 gattggataa catcaaagaa agcagatact ggcaaggcta tctcttctaa attttcaagc
    30121 acaggacttg aataaaggat aatctgacta tccttgtaat caaaattcca tgcagacaag
    30181 tcttggtcag agaagctttt tacaatctgc tcactctggt cttgctctat ttttttatcc
    30241 tctatgaagg aggtcaactc ttttatcagc tgttccttag ccttactagc atctgaaaac
    30301 agttggtcaa gtgtaaaagg ttgcccatct tctgttaagt gaacctttcc tagactggtc
    30361 ttttcagtct cttcaacctt aaaagcaact aaatcataga tttgtttggt cacattacga
    30421 ttaacgactc cctttaaacc tgactcttct tgctctgtat agtagaaaac aagattgtcc
    30481 ttactttcta gcttgtcctt aacatcttga tttatcaact ccctaacaga ggaaatcact
    30541 ttctcccctt ggagaggata ataggcaatc acttcggctt gcccctgacg aaaatgctcc
    30601 ttctgatttc cctcactcaa ttgatcatct ttctcttttt tgagcgattc aatcttttgc
    30661 tcaaaacttt tttgctggta gatcttaaaa gcaataaatc cgcctaatag gcaaatagaa
    30721 attgctaaga taccaatcaa agccaataat acatgtctcg ttttcccgtg tctgccacgt
    30781 cctagtctac ttttattcat atttatatca taacaaattt gagcaataat ttcaatgata
    30841 caatttggca atccacaatt cctctagcaa gccaaagcat cttacatcaa ctccaacatc
    30901 cgtatctgta gagattatgt agttttctat ctatggaatt tctagtaaat tgaagctaga
    30961 atagtagacc tatacttcta aaacattgtt agaaatcgat ttgattgtcc tgatcgattt
    31021 gtcctgttct tatttcattt tactataaaa ctatgaaaag ctaggtcatc tgagaagtaa
    31081 ttactatcga caattgcgat agcgtatact ggtgcgattt gtttgtagct ctggtgggta
    31141 tcaccttcac gttggcgaat tttttctagg ttttgattaa cctgactgca cagataagcc
    31201 cataggcgat tgatgaaaaa attctgatga tgaacctgaa tttcgatgat aacttgaatt
    31261 ccattatcta actccgccaa gacgtctata ctagtataga aatcctgcgc tgagtaggac
    31321 atggaaggca agacgtgaat gttacttccc tccaaaatcg tcacattttt tgctggcaag
    31381 tccagcatat cgcggataaa ttgacaaatc attagttggg ctgatacccg gatgtctgag
    31441 aatcctcctt ttcctccttc tattatagca catttttaaa tctaggtttg ctagattcta
    31501 tgcttctatc tatttattcg gaaaagaaag cttttcttca gaagaaagct aatagcttat
    31561 ttgaaatttt ctcctctctg ttggatagtc ccgtctatct atgttataat gaaagaagga
    31621 tttaaaatcg gaaaaggagt atttatgcta aaattaggtg tcatcggaac tggcgctatc
    31681 agccatcatt tcatagaagc agcccatacc agtggagaat accaactggt cgcaatctat
    31741 tctagaaaac tagaaactgc agcaaccttt gcttctcgct atcagaatat ccaactattc
    31801 gatcaattag aagtcttctt caaatcttct tttgatttag tctatatcgc cagtccaaac
    31861 tccttacatt ttgctcaggc aaaagctgcc ttgtctgctg gtaaacatgt tattctcgaa
    31921 aagccagctg tcactcaacc acaagaatgg tttgatttga ttcaaacagc tgaaaaaaat
    31981 aactgtttta tctttgaagc agctcgtaat taccacgaga aagcctttac tactatcaaa
    32041 aactttttag cagataagca agtgttagga gcagatttca actattccaa atactcttcc
    32101 aagatgcctg acttgttggc tggacaaaca ccaaatgtct tttcagaccg ttttgctggt
    32161 ggagccctca tggatttggg gatttatccc ctctatgctg ctgttcgtct ttttggaaaa
    32221 gccaatgacg cgacttacca tgctcaacag cttgacaata gcattgacct aaatggagat
    32281 ggtaccctct tctacccaga ctatcaagtt cacatcaagg ctggaaaaaa catcacttcc
    32341 aatcttcctt gcgagattta tacaacagat ggaaccttga ctctcaacac gattgagcat
    32401 attcgctcag ctatttttac cgaccaccaa ggaaatcaag tccagcttcc tatccaacag
    32461 gatcctcata cgatgactga ggaagtcgct gcatttgcac acatgatcca gcaaccagat
    32521 ctgaatctct accaaacttg gctgtatgat gcaggctctg ttcatgagct actatatacc
    32581 atgcgccaga ctgctggcat tagatttgag gcagaaaaat gaaaaccaaa ctaccgactg
    32641 aatggcaaga actgagtgac caactcggtt tccaagaatt caccctcatt caaactcaac
    32701 tatttgagcc ccttcttgct ggagaaaacc tcctaggagt gagccaaacc ggaactggta
    32761 agaccctagc gtatctccta ccaagtcttc tcagactaca aaagaaaaaa gcccaacaac
    32821 tcttgattct agcaccaaat acggaacttg ctggacagat ttttgatgta tgtaaaacgt
    32881 gggcagaagc tatcggattg actgctcaac tcttcctttc aggttcaagt cagaaacgac
    32941 aaattgaacg ccttaaaaag gggtcagaaa ttctgattgg aactcctggc cgtatctttg
    33001 aactcattaa acttaaaaaa atcaagatga tgaatgtgga aaccatcatc ctggatgaat
    33061 ttgaccaatt actagatgat tctcagattc actttgtaga aaaaatcact cactacgcac
    33121 ctcgtgacca ccaactggtc tacatgagtg ccacgaccaa gtttgaccaa gaaaagattg
    33181 tgccgaatac acgcactatt gatctctctg atcaaaaatt ggacaatatc cagcatttct
    33241 acatgcaggt agaccaacgt catcgagtgg atatgctacg aaaactggct catgtagagg
    33301 atttccgtgg tctagtcttc ttcaatagcc tgtcagacct tgggaatgcc gaggaaaaac
    33361 tacagtatcg tgatatattg gctgtttccc tcgctagtga tgttaatgtt aaatttagaa
    33421 aaatcatctt agaaaagttt aaagataacc aactaaccct gcttcttgca actgaccttt
    33481 tggctcgtgg aattgatatc gatagcctag aatgtgtcgt aaactttgat attcctagag
    33541 atagcgaaac ctacacacac cgtgctggcc gtactggtcg tatgggcaag gaaggttatg
    33601 ttatcactct cgtcactcat ccagaagaaa tcaaaaaact taaaaagttt gcaagtatcc
    33661 gagaaattgt cctaaaaaac caagaactct atatcaaata aagccctatt gctctataca
    33721 catccagtgt atggagcttt tttataagca attcaatttt atactcatct gctttcaaaa
    33781 agcattctag tccatttccg attaacgatg gactttatca cctccttctc cagtccttgt
    33841 atgacatctt ccaaagttcg aaaggcttta ttctta
//
LOCUS       DAVLZG010000018        33780 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLZG010000018 DAVLZG010000000
VERSION     DAVLZG010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.018"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(115..330)
                     /locus_tag="VYO72_000809"
     CDS             complement(115..330)
                     /locus_tag="VYO72_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707212.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="VYO72_000810"
     CDS             complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="VYO72_000810"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1707213.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2501..2857)
                     /locus_tag="VYO72_000811"
     CDS             complement(2501..2857)
                     /locus_tag="VYO72_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1707214.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3095..3331)
                     /locus_tag="VYO72_000812"
     CDS             complement(3095..3331)
                     /locus_tag="VYO72_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707215.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="VYO72_000813"
     CDS             complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="VYO72_000813"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1707216.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGSRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="VYO72_000814"
     CDS             complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="VYO72_000814"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1707217.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4995..6695)
                     /locus_tag="VYO72_000815"
     CDS             complement(4995..6695)
                     /locus_tag="VYO72_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1707218.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6896..8563)
                     /locus_tag="VYO72_000816"
     CDS             complement(6896..8563)
                     /locus_tag="VYO72_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1707219.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8566..8931)
                     /locus_tag="VYO72_000817"
     CDS             complement(8566..8931)
                     /locus_tag="VYO72_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1707220.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9088..9276)
                     /locus_tag="VYO72_000818"
     CDS             complement(9088..9276)
                     /locus_tag="VYO72_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1707221.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9392..9568)
                     /locus_tag="VYO72_000819"
     CDS             complement(9392..9568)
                     /locus_tag="VYO72_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1707222.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(9679..9877)
                     /locus_tag="VYO72_000820"
                     /pseudo
     CDS             complement(9679..9877)
                     /locus_tag="VYO72_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(10305..11849)
                     /locus_tag="VYO72_000821"
     CDS             complement(10305..11849)
                     /locus_tag="VYO72_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1707223.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNKRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12062..12364
                     /gene="gatC"
                     /locus_tag="VYO72_000822"
     CDS             12062..12364
                     /gene="gatC"
                     /locus_tag="VYO72_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1707224.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12364..13830
                     /gene="gatA"
                     /locus_tag="VYO72_000823"
     CDS             12364..13830
                     /gene="gatA"
                     /locus_tag="VYO72_000823"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1707225.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLSAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13830..15272
                     /gene="gatB"
                     /locus_tag="VYO72_000824"
     CDS             13830..15272
                     /gene="gatB"
                     /locus_tag="VYO72_000824"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1707226.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15401..15961
                     /gene="efp"
                     /locus_tag="VYO72_000825"
     CDS             15401..15961
                     /gene="efp"
                     /locus_tag="VYO72_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1707227.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15983..16372
                     /locus_tag="VYO72_000826"
     CDS             15983..16372
                     /locus_tag="VYO72_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1707228.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            16365..16787
                     /gene="nusB"
                     /locus_tag="VYO72_000827"
     CDS             16365..16787
                     /gene="nusB"
                     /locus_tag="VYO72_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1707229.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQMVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16837..17073)
                     /locus_tag="VYO72_000828"
     CDS             complement(16837..17073)
                     /locus_tag="VYO72_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707230.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(17086..17559)
                     /locus_tag="VYO72_000829"
     CDS             complement(17086..17559)
                     /locus_tag="VYO72_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707231.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17577..17762)
                     /gene="briC"
                     /locus_tag="VYO72_000830"
     CDS             complement(17577..17762)
                     /gene="briC"
                     /locus_tag="VYO72_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1707232.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17921..18688)
                     /locus_tag="VYO72_000831"
     CDS             complement(17921..18688)
                     /locus_tag="VYO72_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1707233.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18685..19551)
                     /locus_tag="VYO72_000832"
     CDS             complement(18685..19551)
                     /locus_tag="VYO72_000832"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1707234.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19588..20955)
                     /gene="accC"
                     /locus_tag="VYO72_000833"
     CDS             complement(19588..20955)
                     /gene="accC"
                     /locus_tag="VYO72_000833"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1707235.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVKKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="VYO72_000834"
     CDS             complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="VYO72_000834"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1707236.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(21386..21871)
                     /locus_tag="VYO72_000835"
     CDS             complement(21386..21871)
                     /locus_tag="VYO72_000835"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1707237.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="VYO72_000836"
     CDS             complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="VYO72_000836"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1707238.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="VYO72_000837"
     CDS             complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="VYO72_000837"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1707239.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="VYO72_000838"
     CDS             complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="VYO72_000838"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1707240.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="VYO72_000839"
     CDS             complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="VYO72_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1707241.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(25903..26127)
                     /locus_tag="VYO72_000840"
     CDS             complement(25903..26127)
                     /locus_tag="VYO72_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1707242.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(26187..27161)
                     /locus_tag="VYO72_000841"
     CDS             complement(26187..27161)
                     /locus_tag="VYO72_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1707243.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(27161..27595)
                     /locus_tag="VYO72_000842"
     CDS             complement(27161..27595)
                     /locus_tag="VYO72_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1707244.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27689..28474)
                     /locus_tag="VYO72_000843"
     CDS             complement(27689..28474)
                     /locus_tag="VYO72_000843"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1707245.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28844..30208
                     /locus_tag="VYO72_000844"
     CDS             28844..30208
                     /locus_tag="VYO72_000844"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1707246.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYYAFFGE
                     SKED"
     gene            30211..30582
                     /locus_tag="VYO72_000845"
     CDS             30211..30582
                     /locus_tag="VYO72_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1707247.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30796..32070
                     /gene="serS"
                     /locus_tag="VYO72_000846"
     CDS             30796..32070
                     /gene="serS"
                     /locus_tag="VYO72_000846"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1707248.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(32095..32994)
                     /locus_tag="VYO72_000847"
     CDS             complement(32095..32994)
                     /locus_tag="VYO72_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1707249.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(33104..33652)
                     /locus_tag="VYO72_000848"
     CDS             complement(33104..33652)
                     /locus_tag="VYO72_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1707250.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
BASE COUNT         9913 a         7743 c         6229 g         9895 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
      121 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata
      421 attagttcag aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
      481 tctacaccat aaatatttgc taataaaaat actgtattat taccctctta aggtgcgaaa
      541 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
      601 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttctctag ctcaaaaact
      661 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
      721 catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca
      781 tccttaatag agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
      841 tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga
      901 gcaaactagg aagctagccg caaattgctc aaaacactgt tttgaggttt cagatagagc
      961 taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtatgactat gcttgtcaat
     1021 agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga
     1081 acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca
     1141 tcttcattat agcacatata catcagttgt acaaataata tgatattttt ttattagtcc
     1201 tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa
     1261 accttccatt ctacggatca aacctgcata atcatgctta tctgccaaag cgatcccaat
     1321 caatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc
     1381 atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgct gtgggaaatt
     1441 gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat
     1501 acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata
     1561 ttcagctaaa acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc
     1621 ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa
     1681 agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat
     1741 cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct caaaggcagc
     1801 tttcatggaa cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc
     1861 cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc
     1921 atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg
     1981 acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt
     2041 aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac
     2101 aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat
     2161 aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt
     2221 tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc
     2281 ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata
     2341 aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac
     2401 cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct
     2461 ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt
     2521 cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat
     2581 aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac
     2641 gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt
     2701 ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt
     2761 ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac
     2821 atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt
     2881 acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc
     2941 gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc
     3001 tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct
     3061 gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc
     3121 atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga gaatgaattt
     3181 caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca
     3241 acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg
     3301 accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca
     3361 actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca
     3421 gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaaca
     3481 aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt
     3541 tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca
     3601 aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg
     3661 attacacgtg aacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc
     3721 attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact
     3781 tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg
     3841 ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt
     3901 tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag
     3961 tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga
     4021 acaccaaatc cttcttcgta agtacgacgt accaagtgtc ccggtccttt aggagcacac
     4081 atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt gaaaccatgg
     4141 gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct
     4201 tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt agcttctact
     4261 actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca
     4321 ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg tccttgtgaa
     4381 ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca
     4441 tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct
     4501 ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag
     4561 caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat
     4621 ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag
     4681 gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa
     4741 tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct
     4801 gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa
     4861 tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa
     4921 cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtagtt
     4981 ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca
     5041 gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga
     5101 acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag
     5161 tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac
     5221 tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga
     5281 ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg
     5341 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
     5401 attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc
     5461 actaactgac gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca
     5521 acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct
     5581 tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg
     5641 actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc
     5701 aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca
     5761 gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc
     5821 gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca
     5881 atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt
     5941 gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat
     6001 tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc
     6061 tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga
     6121 gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt ttctaaagca
     6181 gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg
     6241 acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta attgtactta
     6301 gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt cccaatccct
     6361 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat agcatccgca
     6421 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
     6481 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga
     6541 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca
     6601 ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac
     6661 cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa
     6721 ataacttgtt actatcatac cattttttca aaatttttca agataaaaga agaaattttc
     6781 tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt aaaaagatac
     6841 cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
     6901 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
     6961 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
     7021 caccgacata gaaggttacg atttcactat cttcatccaa catatgtttc aaggtttcag
     7081 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat
     7141 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
     7201 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
     7261 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
     7321 ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
     7381 tgtttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt
     7441 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
     7501 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
     7561 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
     7621 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
     7681 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
     7741 ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
     7801 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
     7861 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
     7921 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
     7981 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
     8041 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
     8101 cttcaacagc gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
     8161 aaactgttaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
     8221 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
     8281 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
     8341 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
     8401 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
     8461 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
     8521 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
     8581 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
     8641 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
     8701 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
     8761 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
     8821 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
     8881 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
     8941 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
     9001 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
     9061 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
     9121 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
     9181 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
     9241 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
     9301 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
     9361 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
     9421 ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
     9481 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
     9541 attttcttac aacaatatct aaatccaaat acagtacacg agactcgctt acatactttg
     9601 gaataaaata cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
     9661 cagaatacta ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt
     9721 ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
     9781 ataatagatg aacacaaaga gattttattg ttgtttcaac tttatccata taagcattat
     9841 ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatctcatt tctttttatt
     9901 cccatcatat gtttctacgt aaccattatt ttcgcccatt cgttcgtaaa accataccag
     9961 tggagatttt agatgaagtc ccattacggt ttacaatttt tacattacga cacggagttt
    10021 tacaaatcga tttcatttgc caaacgtagt tagtaaggca gttagctagg ctacctactt
    10081 tctgctacga cggaaaaatc cacaaatcaa taccattcgt ggatttttcc tagtgaagcg
    10141 tttaggtaag ccgccatagc ggttaccgat tattagatta cgacacggag tttggcaaat
    10201 cgattctatt tgccaaacgt agttagtgag gcagttagct agttcgccaa atagcgacta
    10261 gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct
    10321 aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga
    10381 aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgatga catccgttca
    10441 tccaaatcct caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact
    10501 tccgcattat attctccttc catacggtgc ttaaagactt caaactggag ttgacctaca
    10561 gcgcctagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc
    10621 actagttgct caatcccctt gtggaaggat ttttgcttca tgacattctt agcagaaact
    10681 ttcatgaaaa tttcaggagt aaaggttggc aatggttcaa attcaaattt gtttttccca
    10741 actgtcaagg tatccccaac ctgataagtg cctgtatcgt aaaccccgat aatatcacct
    10801 gccacggcat tggtcacatt ctcacgactt tccgccataa actgggtaac attagacagt
    10861 ttagccccct taccagtacg agggagatta acactcatgc cgcgctcaaa ttcgccagat
    10921 acgatacgga caaaggcaat acggtcacgg tgacgagggt ccatgttggc ttggatttta
    10981 aagacaaagc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg
    11041 tgaccatgtg gttctggagc aaacttgagg aaggtttcaa ggaaggtctg cacaccaaag
    11101 tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct
    11161 gaaaactcat tcccggcttc atttaaaagc tcaatatcat ccttgacttg ctcgtagaaa
    11221 ggattgctac caaaaagttt gtccccatct tctagactag caaaacgctc atccccttta
    11281 taaagctcta aacgtttgtt atagaggtca tacaagccct caaaggcttt ccccatcccg
    11341 ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc ttgtaagaga
    11401 tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaagac tggaatgcca
    11461 cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc
    11521 acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc
    11581 tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca
    11641 gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccaatcaga tttagcaaaa
    11701 gtccctgttt tcttcccttt taccgtacca gcctcacgaa tttcaccccc aaagtagagt
    11761 aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga
    11821 cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgattct ctatttttct
    11881 tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc aacactccat
    11941 tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt
    12001 tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa
    12061 gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc
    12121 tgaaaaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt
    12181 gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac
    12241 tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt
    12301 acctgaaaaa gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc
    12361 ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt ctctaaggaa
    12421 atttctgcaa cagaattgac ccaaacaaca cttgaaaata tcaagtctcg tgaggaagct
    12481 ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat
    12541 gaagctggaa ttgatgctga caatgtcctt tcaggaattc cacttgctgt taaggataac
    12601 atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca
    12661 atctttgatg cgacagctgt tgccaatgca aaaaccaagg gcatgattgt cgttggaaag
    12721 accaacatgg acgaatttgc tatgggtggt tcaggtgaaa cttcacacta cggagcaact
    12781 aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct
    12841 gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa
    12901 cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc
    12961 ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag
    13021 gaaaatgccc tcttgctcag cgctattgcc agcgaagatg ctaaagactc tacttctgct
    13081 cctgttcgca tcgccgactt tacttcaaaa atcggccaag acatcaaggg tatgaaaatc
    13141 gctttgccta aggaatacct cggtgaagga attgatccag aagttaagga aacaatctta
    13201 aacgcggcca aacactttga aaaattgggt gctattgtcg aagaagtcag ccttcctcac
    13261 tctaaatacg gagttgccgt atactacatc atcgcttcat cagaagcttc atcaaacttg
    13321 caacgctttg acggtatccg ttacggctat cgcgcagaag atgcaaccaa ccttgatgaa
    13381 atctatgtaa acagccgaag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg
    13441 ggtactttca gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc
    13501 cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt
    13561 ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg
    13621 tacttagccg acctattgac catacctgta aacttggcag gactgcctgg aatttcgatt
    13681 cctgctggat tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct
    13741 gaggaaacca tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa
    13801 caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatt ggacttgaag
    13861 tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cacttcggaa
    13921 atgatcaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt ctgccagttc
    13981 tcaataaagg ggttgtcgat gccggaatca aggctgctct tgccctcaac atggacatcc
    14041 acaaaaagat gcactttgac cgcaagaact acttctatcc tgataacccc aaagcctacc
    14101 aaatttctca atttgatgaa ccaatcggat ataatggctg gattgaagtc gaactagaag
    14161 acggtacgac caagaaaatc ggtatcgaac gtgcccacct agaggaagac gctggtaaaa
    14221 acacccatgg tacagatggc tactcttatg ttgacctcaa ccgccaaggg gttcccttga
    14281 ttgagattgt atctgaggca gatatgcgtt ctcctgaaga agcctatgct tatctgacag
    14341 ccctcaagga agttatccag tacgctggca tttctgacgt taagatggag gaaggttcga
    14401 tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca agagaaattc ggtaccaaga
    14461 ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc
    14521 aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg
    14581 atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct
    14641 acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc
    14701 ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt
    14761 tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa
    14821 aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg
    14881 ctcagttctt gaatactgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact
    14941 tggttgaaat gattgccatc atcgaagacg gtactatttc atctaagatt gccaagaaag
    15001 tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta
    15061 tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata
    15121 acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag
    15181 gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg
    15241 cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt
    15301 tttttcttct ctcccaactc ccaataacta ttttggcttt atttccagag tattttatgg
    15361 taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt
    15421 aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag
    15481 tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac
    15541 tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga
    15601 gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga
    15661 aacttacgac caatacgaaa tccctgtagt caatgttgaa aacgaattgc tttacatcct
    15721 tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc
    15781 tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac
    15841 aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat
    15901 cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta
    15961 atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc
    16021 cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc
    16081 tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcattta
    16141 tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt
    16201 aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat
    16261 ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac
    16321 accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat
    16381 tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg
    16441 gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa gatacggatg
    16501 tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac
    16561 tagataagca aatcactcag catttaaaag caggttggac cattgaacgc ttaacgctcg
    16621 tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac actcctcaga
    16681 tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc
    16741 gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt
    16801 ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat gataatagat
    16861 ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg
    16921 gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc
    16981 aatcagacta taatataata aactaattgg atctctgtga gatagtatca aatggctaat
    17041 cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg gaaagaaggt
    17101 attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaggcag
    17161 gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa gcacggtaaa
    17221 atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc aaaaattacc
    17281 gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc agttccagct
    17341 ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta atagaaggaa
    17401 acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta accctaaaat
    17461 gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa
    17521 aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac
    17581 cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata
    17641 tagggagcaa attctctata atataaccat ctactatatc catcttccca aacagcaaga
    17701 ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt tgtacctgtc
    17761 attgcaagta ccttcttaaa atagattgtt gtaggttcac atttatagta tatttctttt
    17821 tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa ttacattttt
    17881 ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt
    17941 gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc agctccgttt
    18001 ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt tcagaaatca
    18061 ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc agttctgctg
    18121 cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct ggactgagaa
    18181 tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga gccagagccc
    18241 cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg tcactcattt
    18301 ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg acaccaggat
    18361 aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca gcctgtttca
    18421 tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc cgtttgaggt
    18481 tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga tctccaagcc
    18541 aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca tgtaattgga
    18601 taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg
    18661 cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc tgactaggct
    18721 agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc catgttctaa
    18781 taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat tttcaatcac
    18841 acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat cgccttccat
    18901 agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca ggtaaaagag
    18961 accagcattt gaatggcgtt taaccgccgc agagatctta gccatctgca tgagactcat
    19021 gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg gcaatttttc
    19081 gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac ccatagaagc
    19141 catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa taagagcagt
    19201 tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca gtttcttttg
    19261 gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt ctttgaaggt
    19321 tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg tatagctaca
    19381 gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct tacagcctgg
    19441 acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt ccctaaccga
    19501 acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca ttgattcccc
    19561 ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag gtaagaaggt
    19621 ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg aaatgaggtc
    19681 aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga gggcacgttg
    19741 cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg caatcatact
    19801 atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc gcaagccaac
    19861 tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa agttaaaggc
    19921 tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa tatcttcttg
    19981 cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga tatcaacacc
    20041 tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct ccatgaaata
    20101 gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct catagccaac
    20161 aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt ttccgattgc
    20221 aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac aatcccgttc
    20281 acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa tgtgccgagc
    20341 tggatagata acccgttcta tgtacatggc accattgcca taattggcct tggcctcact
    20401 agaggcagtt tcaaaggcag aaacgaggtc atctggtttt ttaaccttac gaatcccttt
    20461 accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt cagcaacaat
    20521 caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag gcacacctgc
    20581 tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa catgaccaga
    20641 tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg aattttcact
    20701 gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag ctgatagaac
    20761 tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa ctgcttcatc
    20821 tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta ccgtcgcaat
    20881 ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat tggcaattaa
    20941 aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag ggtaccactg
    21001 gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt gccacgacgt
    21061 tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt cttgaactta
    21121 accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt tgataactcc
    21181 aacacaccgg cagtttgcgc caaggcttcc ataatcagaa cacctggcat aactgggtat
    21241 tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat agcaacaatg
    21301 gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg gtggggaaga
    21361 gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta ccaaactcaa
    21421 ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga gctgggattt
    21481 cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg acactatcac
    21541 caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact ccaacaagtg
    21601 gactctctac aagatttccc tcagtagcca cacttgcttc agctggagct ggaacttctt
    21661 ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt gctagaacgg
    21721 gtgctggagc gacttgagtt gcaacttcag gcacaggtct tgcttcattc ttgctaaact
    21781 gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg tcaaattgag
    21841 tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac gtttgaaagc
    21901 aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg gaatttcttt
    21961 ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt cacttgtccc
    22021 agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag cttctactgc
    22081 acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag gtacttcctt
    22141 accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag ttgacgttcc
    22201 gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca aggctagttt
    22261 gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt aggcatcaca
    22321 agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt cagcgtgttc
    22381 aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat tgcgatcctt
    22441 atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg ttaaggcttg
    22501 gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca acatcacatc
    22561 ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg atgaagagca
    22621 ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga
    22681 agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg gtcctttttc
    22741 atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag atgcaacgat
    22801 aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat ttacagcctc
    22861 ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat ctttttttac
    22921 aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat caaagtcact
    22981 atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac tattccaaaa
    23041 ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca ctactcgatt
    23101 tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat caatggcaat
    23161 cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg caacctgctc
    23221 tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa tcttatctga
    23281 taagatagct gtcatatcag actcaatcat tcctggagca atcacattga ctcgtatatt
    23341 ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag ccttagaagc
    23401 agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca tattaatgat
    23461 agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat taaaggcacc
    23521 agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga gcataagagt
    23581 atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt ctgcaatagc
    23641 ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa tgggaaccac
    23701 cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc cacgactgtt
    23761 taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac caattccacg
    23821 actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc tttcaaaact
    23881 tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat cttccacatg
    23941 agctaagtga gcagtttgat caattttttt aacaaagcct gacaagactt tccccggtcc
    24001 aatctctata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt catagaaacg
    24061 aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc
    24121 agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct gagctagagt
    24181 ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac ctgacacctt
    24241 aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc
    24301 aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg gagtaaccac
    24361 tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg tattgagaac
    24421 tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc cacgcttagc
    24481 taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg cagagtattc
    24541 tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca ataaacggta
    24601 gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc
    24661 ttcttccgta tcgatgagat aacgcaaatc ataacctagt acctggctcg ctcgatcaat
    24721 cgtttcttta acaatcggat actgatcata gaaatcccgt cccatcccta gatactgggc
    24781 accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct gtccagcgag
    24841 aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg atttcttcag
    24901 ctgtttcttc tttagaaaca agccctgcga tttgacctgc cataacagag ccaccatcca
    24961 catcaccgtg aacaactgct ttggctagag cacctgctcc catttgttca aagatttcta
    25021 aatcaggatc ttcttgctta aaggcatctt tttcagccag ttcaaaatct ctagtcaact
    25081 gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat
    25141 cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct tttgcaacta
    25201 caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc gcagcacctt
    25261 caccatccgc aattcctcct gcagcaataa caggaataga tacagctgtg gctacctgtc
    25321 gcaccaaagt catggttgtt aatttaccga tatgcccccc agcttccatt ccttctgcaa
    25381 taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcaacacta ggaacgacag
    25441 gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga tttcctgctc
    25501 ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct tccacaaagg
    25561 gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg attttatcaa
    25621 tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct aatcctccag
    25681 ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct ccttggaaaa
    25741 taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct ccaaccttcc
    25801 ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta cctaaacaag
    25861 agggagtggg tttctcccta ctccttctac ttaatattct gcttattttg cttgctcttc
    25921 aacgtaagca accaagtcac caactgtttt caagtcattt tctgcttcga tttggatatc
    25981 aaaagcatct tcgatttctg agattacttg gaacaagtcc aatgaatctg cgtccaaatc
    26041 atcaaaagtt gattcaagtg ttacttctga tgcgtctttt ccaagttctt caacgataat
    26101 ttcttgtact ttttcaaata ctgccatgat aggactcctt taaaataaat agttttttta
    26161 taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc ccaggtcaaa
    26221 cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat gagaccttgt
    26281 tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc atattccatc
    26341 atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt atccaaaata
    26401 cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat aggagattca
    26461 tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa gactgtgcgt
    26521 ccatccatct tcaaaaatga atctgcactt tcttgatctg aaaatggaga atgcaaacct
    26581 gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact ctcagctaag
    26641 aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc aaacaacaca
    26701 gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc aatcaccaag
    26761 cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc aaatacaaat
    26821 ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcaccaat attagcttga
    26881 acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag gatgataaaa
    26941 tccagttctt ttcctgttat tccagctttt gccatcagtt tcttagcaac ctctgtagcc
    27001 aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt tcgacttgaa
    27061 atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac cacttgctct
    27121 ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa tcctccaaaa
    27181 attggtaaag attagtcaag cctttaccca tgacagcaat ttcttcctcg ctcatgccat
    27241 caataatttt ttctaccatg gccttgtgga agcgtttatg cagtctatga atcaagcgac
    27301 ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga actcgctcaa
    27361 tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga gttaccatca
    27421 actcttttga cacttgactt ggagtcacat ctggagcctt accgatgaca tcaatcgtat
    27481 gcatttcttt gatggagata tccttaaaac gactacctct caagttcact tcctcaatta
    27541 caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag tccatttttc
    27601 atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa gaattatatc
    27661 aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt cttcttctct
    27721 ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat ttctgtaggt
    27781 tcagttctaa agtagcgtaa ccctgccagt ctttaaattg gctctcccaa accaacttct
    27841 taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc tgttctctcg
    27901 tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct agggcttttt
    27961 ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca ccgatactgc
    28021 ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca aaggcttgga
    28081 taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata ttcgctgcgg
    28141 cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc ttgattttat
    28201 aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca tcctcatcca
    28261 ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca ttggcattga
    28321 ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct aaaatctcct
    28381 cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta aggattgcca
    28441 agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat tttataagca
    28501 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgtaa cctcaaaaca
    28561 gtattttgag ctgacttcgt cagtcttatt tacaacctca aagcagtgct ttgagcagtc
    28621 tgcggctagc ttcctagttt gctctttgat tttcattgag tgttaaatta tttcactgtc
    28681 aaagtatatc ttttttagga gcagaaagca agaaaaaatc gactgaaagt gtctcagccg
    28741 ataagaaagg ctcgctttag gctagaaagc atcttatttt cttcattgaa aaaagccttt
    28801 ctttctgcta taatcgtata aaatacttac tttaggagtt cttatgaaag ttgttaaatt
    28861 tggaggtagt tctcttgcct ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag
    28921 cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac
    28981 taaggttacg gatgccctga ttaaatacta ccgcgactat gttgcgggta acgatattag
    29041 caagagccaa agctggatta tcgaccgcta tgctgctatg gttagtgaat tgggactaaa
    29101 accagctgtg ctagaaaaaa tttctaaaag cattcacgcc ttggccactc ttcctattga
    29161 agaaaatgaa tttctctacg atactttcct agcagccggt gaaaataaca atgccaaatt
    29221 gattgctgcc tactttaacc aaaatggtat cgatgcacgc tatatgcacc ctagagaagc
    29281 tgggattgtg gtcacaagtg aacctggtca cgctcgcatc attccatcaa gttatgacaa
    29341 gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac
    29401 taaggaaaat caaatctgta ctttctcacg tggaggatct gatattacag gttctatcat
    29461 tgctgctggt gtcaaagctg acctctatga aaactttacg gacgttgatg gtatctttgc
    29521 agcccaccct ggtattatcc accaaccaca ctcgattcct gagttgacct accgtgaaat
    29581 gcgcgagttg gcctatgcag gcttctcagt ccttcatgac gaggctcttc ttcctgccta
    29641 ccgtggaaaa attcctctgg ttatcaagaa taccaacaac cctgaccatc caggtactcg
    29701 tatcgttcta aaacacagta atgatgaatt tccagttgtg ggaattgctg gtgactcagg
    29761 ctttgtcagc attaatatgt cgaaatacct catgaaccgt gagattggat ttggccgcaa
    29821 ggttctgcaa atcctggaag aacttaacat cggttgggaa catatgccaa caggtatcga
    29881 cgatctttct atcattctcc gttctcgcca actaactccc atcaaggaag aagaaatcct
    29941 gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa atcgaacacg acctttctat
    30001 cattatgatt gttggtgaaa aaatgaagag ccatatcgga gtgactgcta ctgcgacacg
    30061 cgctctatct gaaaacaaaa tcaacatcca gatgatgtct caaggttcta gtgaagtttc
    30121 tattatgttt gttgtcaata aagaccaaga gaaagcagca attaaagccc tctactatgc
    30181 cttttttgga gaaagtaagg aagactaagc atggctcaat cacttaacaa aacagtactc
    30241 ctcagtacga caggcacttc ctacctctct atcgctggga aagttgggaa attccttgtc
    30301 ggagatcagg ctttggaatt ttacccagat gtcaatgtcg aacaatttat ccagattcct
    30361 tggagccata tcaatcagat tggagccaat gtcactggac gcaaagtcag ccgccacttc
    30421 gaagtcttta cagacaaagg aaaattcctc tttgcttcaa aagactcagg tgccattctc
    30481 aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca aacttccgac cctgattcag
    30541 acaattagcc aaaaatttaa aaatctattt gcaaaaaagt agaaacttta gtataatcat
    30601 agcaacggat aagtaggtta tcttcttctt tcagaaagtc tgcgggtact gcgagcagat
    30661 aggggggata ggtgaaattc taccgttagt aacaattaca tacacaatca agtgcacacc
    30721 tgtgaagttg gatggaaccg tggccctgcc actccaacgt tttgtcaggc gtgctttttt
    30781 cataaaggag ttcttatgtt agatatcaaa cgtattcgta cagattttga agctgtcgca
    30841 gaaaaattag ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa agaaatcgat
    30901 gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca aagcagaacg taacacagtt
    30961 tctgctgaga ttgcccaagc taagcgcaac aaggaaaata cagatgacaa gattgctgcc
    31021 atgcaaaatc tatctgctga ggttaaagcc ttggatgctg aattggcaga aatcgatgct
    31081 aaattgacag aatttacaac gactcttcca aatatcccag ctgacagcgt tcctgttggg
    31141 actgacgaag acgacaatgt ggaagttcgc cgttggggta ctccacgcga gtttgacttc
    31201 gaacctaaag ctcactggga tctcggtgaa gaccttggta tccttgactg ggaacgcggt
    31261 ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc tcggtgctcg tttggaacgt
    31321 gctatctaca actttatgtt ggatgaacat ggaaaagaag gctatactga agtcatcaca
    31381 ccttacatag tcaaccatga ttctatgttt ggtactggtc agtatccaaa atttaaggaa
    31441 gatacttttg aactcagcga taccaacttt gtcttgattc caactgctga agttcctctg
    31501 acaaactact accgtgatga aatcttagac ggcaaagatc ttccaatcta cttcactgcc
    31561 atgagtccgt cattccgttc tgaggctggt tctgccggtc gtgatacgcg tggcttgatc
    31621 cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac
    31681 gaagaattgg aaaaaatgac agccaacgct gaaaacattc ttcaaaaact caaccttcca
    31741 taccgtgtcg ttgctctctc tactggagat atgggcttct cagctgcgaa gacttacgac
    31801 ttggaagtgt ggattccagc acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca
    31861 gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg
    31921 aaactccttc ataccttgaa cggttctgga cttgcagttg gacgtacagt ggctgcaatt
    31981 cttgaaaatt accaaaatga agatggttct gtgaccatcc cagaagcact tcgtccatac
    32041 atgggtggag ctgaagtcat caaaccataa aaaataaggt ttagctattt ctagctagac
    32101 cttttttcgt aaccaaatca gataagcacc tagtacaaag aataaaatag ttaggcatat
    32161 aatggtttca gccaatacca ggtaatccag aaatggaagt ttcaaaattc cctgagccat
    32221 cttgagcgag gtcgctgtga taatggttgg gaaggtgagg gctgagaagg ctggttgaaa
    32281 accttgtttt aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg attgagaagc
    32341 caaaatcatg acaatcaaga cccaagtcgg caggctggtt cctcctactc gaactagaga
    32401 agccaagagt agagagaaag gagcacagta gattccttct tgtccaagca aggctagtgg
    32461 gagtggatgt ttctttaaat cgctataaat aaggggatag agatagaagg tcaagagaaa
    32521 accaaaactc aaggtcgcat aggcaatttc gataatacct accagaggat aggtcaaggc
    32581 agccactgct atccccacat agagaaccgt ccagcttgga gtggcatgaa ccctccgccc
    32641 tggacaagca aacttgatgg taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa
    32701 ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga cataggtcga
    32761 taaaatcatc ccagccatag gaaaggttgc cattcctgac aaaagagggg gcttggtcaa
    32821 ttcttgcttg gtttctttcc aattaaagag atgcagaatt agaaagtaaa tccataaaac
    32881 caaaccagtc agactaaaaa gatgggatag aaccggcaac gtatctaaaa taagatttcc
    32941 agctcctgcc aaacctagca aacaacctga aaatactaag gggagttttt tcatcctaac
    33001 ctccaataat catgttagtt tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa
    33061 acgaagtccg attatttcag acttcatttt actcagatat gaattaggca taaggttgca
    33121 attctggatt aattggtgta ttagctaagt tgttggcata gttacagagg attgctaggc
    33181 tgacaccaaa aaccacatcc aaggcatttt gttgagtgta gccagcttct aaaaactcag
    33241 acaaggcttc atctcctaca cgacccttgg tattgataac tgccaaggta aacttagcta
    33301 gggtatccaa tttaggatct gtttcaattg gagtacgatt gcgaagagct tgaatcaagt
    33361 catcattcat ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac
    33421 aaccattggt cacggctgcc gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt
    33481 tgcgacggtg gatagatgag acaatttggt aggcttctaa aacagtcggg gcattggcca
    33541 agagaccgat taggttggga atatagccat tgttgtcttt ttctactgtt tcaagaattt
    33601 ctttcacttc tgctggtgct gactctactg tatggatagt aaatgttgtc ataagatacc
    33661 tcttttctta ttattgacac taatattatt ggaaaatctt ataaaatcct gattcctaag
    33721 tttatctaag ataaagcttt attctctcat aagattttcg ttgttatatt agtttatcac
//
LOCUS       DAVLZG010000019        32034 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLZG010000019 DAVLZG010000000
VERSION     DAVLZG010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32034
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.019"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(426..2153)
                     /gene="ezrA"
                     /locus_tag="VYO72_000849"
     CDS             complement(426..2153)
                     /gene="ezrA"
                     /locus_tag="VYO72_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1707251.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAESYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2235..4181)
                     /gene="gyrB"
                     /locus_tag="VYO72_000850"
     CDS             complement(2235..4181)
                     /gene="gyrB"
                     /locus_tag="VYO72_000850"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1707252.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4196..4759)
                     /locus_tag="VYO72_000851"
     CDS             complement(4196..4759)
                     /locus_tag="VYO72_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1707253.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTSFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4844..5398)
                     /locus_tag="VYO72_000852"
     CDS             complement(4844..5398)
                     /locus_tag="VYO72_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1707254.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5409..6632)
                     /locus_tag="VYO72_000853"
     CDS             complement(5409..6632)
                     /locus_tag="VYO72_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1707255.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPRLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6669..9119)
                     /locus_tag="VYO72_000854"
     CDS             complement(6669..9119)
                     /locus_tag="VYO72_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1707256.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMGREYQRSLTLILDRRIVGKRYGKQIVVSLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9319..10248)
                     /locus_tag="VYO72_000855"
     CDS             complement(9319..10248)
                     /locus_tag="VYO72_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1707257.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10388..10675
                     /locus_tag="VYO72_000856"
     CDS             10388..10675
                     /locus_tag="VYO72_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1707258.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10709..12043)
                     /gene="ciaH"
                     /locus_tag="VYO72_000857"
     CDS             complement(10709..12043)
                     /gene="ciaH"
                     /locus_tag="VYO72_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1707259.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12033..12707)
                     /gene="ciaR"
                     /locus_tag="VYO72_000858"
     CDS             complement(12033..12707)
                     /gene="ciaR"
                     /locus_tag="VYO72_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1707260.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12816..15362)
                     /locus_tag="VYO72_000859"
     CDS             complement(12816..15362)
                     /locus_tag="VYO72_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1707261.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15485..15925)
                     /locus_tag="VYO72_000860"
     CDS             complement(15485..15925)
                     /locus_tag="VYO72_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1707262.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15900..16769)
                     /locus_tag="VYO72_000861"
     CDS             complement(15900..16769)
                     /locus_tag="VYO72_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1707263.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16747..17247)
                     /locus_tag="VYO72_000862"
     CDS             complement(16747..17247)
                     /locus_tag="VYO72_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1707264.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17258..17956)
                     /locus_tag="VYO72_000863"
     CDS             complement(17258..17956)
                     /locus_tag="VYO72_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1707265.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17949..18185)
                     /locus_tag="VYO72_000864"
     CDS             complement(17949..18185)
                     /locus_tag="VYO72_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1707266.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18285..19211)
                     /locus_tag="VYO72_000865"
     CDS             complement(18285..19211)
                     /locus_tag="VYO72_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1707267.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19286..20101)
                     /locus_tag="VYO72_000866"
     CDS             complement(19286..20101)
                     /locus_tag="VYO72_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707268.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20105..20425)
                     /locus_tag="VYO72_000867"
     CDS             complement(20105..20425)
                     /locus_tag="VYO72_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1707269.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20587..20667)
                     /locus_tag="VYO72_000868"
                     /pseudo
     CDS             complement(20587..20667)
                     /locus_tag="VYO72_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20711..22708)
                     /gene="metG"
                     /locus_tag="VYO72_000869"
     CDS             complement(20711..22708)
                     /gene="metG"
                     /locus_tag="VYO72_000869"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1707270.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22832..24091)
                     /locus_tag="VYO72_000870"
     CDS             complement(22832..24091)
                     /locus_tag="VYO72_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707271.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24093..24794)
                     /locus_tag="VYO72_000871"
     CDS             complement(24093..24794)
                     /locus_tag="VYO72_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707272.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24778..25977)
                     /locus_tag="VYO72_000872"
     CDS             complement(24778..25977)
                     /locus_tag="VYO72_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1707273.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26263..27609
                     /gene="gor"
                     /locus_tag="VYO72_000873"
     CDS             26263..27609
                     /gene="gor"
                     /locus_tag="VYO72_000873"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1707274.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            27806..28342
                     /locus_tag="VYO72_000874"
     CDS             27806..28342
                     /locus_tag="VYO72_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1707275.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(28543..28758)
                     /locus_tag="VYO72_000875"
     CDS             complement(28543..28758)
                     /locus_tag="VYO72_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1707276.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28856..29176
                     /locus_tag="VYO72_000876"
     CDS             28856..29176
                     /locus_tag="VYO72_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707277.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29207..29545)
                     /locus_tag="VYO72_000877"
     CDS             complement(29207..29545)
                     /locus_tag="VYO72_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707278.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29557..30276)
                     /gene="trmD"
                     /locus_tag="VYO72_000878"
     CDS             complement(29557..30276)
                     /gene="trmD"
                     /locus_tag="VYO72_000878"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1707279.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30266..30784)
                     /gene="rimM"
                     /locus_tag="VYO72_000879"
     CDS             complement(30266..30784)
                     /gene="rimM"
                     /locus_tag="VYO72_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1707280.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELTLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30814..31602)
                     /locus_tag="VYO72_000880"
     CDS             complement(30814..31602)
                     /locus_tag="VYO72_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1707281.1"
                     /translation="MKRFEVSTEIGSLSVTYKKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
BASE COUNT         9462 a         7038 c         5758 g         9776 t
ORIGIN      
        1 ttttagaggc ctatttaccg tggactaaag ttgtacaaga aaagtgcaaa taagaaatct
       61 ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag acttcgttat
      121 tggacggtta ccaagttact caaagtacag atttgaagct gcagataaga ctgacgaaat
      181 cactttaata ctaaatgaaa atcaaaaagc aaactaagaa gctagcctca ggctgtactt
      241 gagtacggta aggcgacgct gacgtgattt gaagagattt tcgaagagta taaaacactg
      301 ttttgaggtg gtggataaat cggctgggta aaaactcaat ctcaggagaa aatgaagtaa
      361 atctccccgc aactatagaa aaagatttga ttctgctcct cacacaataa aatctttttc
      421 ttttattaaa aacgaatcgt ttcacgtgtt ttctcatatg aggtaacaaa gcgattagtt
      481 acaccaggct ctgccacttc caatgcttga gaaatcttgt caaatgaagc gtgataatca
      541 aattcttttt caaaaatatc taaagcttcg ttaaatgctt cttgaatgcg ttcatcaaat
      601 gagcgatagc ggttagaata ttgcaagagt tgctctgtca aagttgcata ttgtacaata
      661 ttataagttt ccgtttctaa agcttccata tcattcgttg caatttcaag aactcgggta
      721 acagattcaa tgttaatcat tttttgttct aactcaacca ttaaatcctc ggtattattg
      781 cttgccgtaa agaataactt caagaaagtt tgtggaatac ctggcagatt gcgtttttcc
      841 atgtatcgct tgatagtatg gagacgattg acataaacat tggccttttg acgtgcatta
      901 atatcatctt tctcaatttg tgtcaggcgc tcactaactg aaatttgctc atcttcaata
      961 tcttttagtt gagtttgtaa atcctcaaga ttttcttcaa gaactgaata agcttgggtt
     1021 ggttcttctt gattcgaagt tacctcaaca atagctgcct caaaactctc taattctgtc
     1081 tgaatacgac gaacatggct tgcagctgtc tcaggaagta aataggtctt gttcaaacgt
     1141 gcaatatctt ctcccaataa agtattattc tctttcatat gttgaaggta agttggaaga
     1201 gttgcaagta gattttccac tactttctga gcagcaattt ctcgagtaaa aatatcatac
     1261 aaggcattga tttcctcttg tgcctgtcca ttctcatatt cggcattatc caattccaac
     1321 tgacgaatat tctcttggtt tttcttgaat gcttcataaa gcaagtggaa acgcgcttca
     1381 atatccgttt caacaaaatg ataattagca tcaattagtt tacgataacc ggcttccaaa
     1441 tcctgtaatt gatctggcaa ttctgtagaa agcgtcgtaa ccaaggctgg aacacgatcc
     1501 acaatatgac ttaaggccaa aatgtgattt tctgtattat ccaaaatcac tgcggcttcc
     1561 acagggtcac ccgatgaatt caaggttaca aattgtgaaa attcagattg gatattttct
     1621 aattgttttt caatttcatc caaggcttga ccatactgtt ctgaattttc agcaactcta
     1681 tgctgaagtt cctcaaataa atccaaagca tgaagaacac gaccactatt tttagattct
     1741 tgcttctcta agtctgccaa agcattgcga attgccgcaa tatcttcttc aatcaaagta
     1801 atttgactct caatttggtc aatttgatga ctggccttga gaaaacgaaa tgaatggtta
     1861 tagctctctg cttcaaagag attattttca atatcggcaa aagagttgag agataaatcg
     1921 acccattttt gattccattc acggaaagcc acttgacttt gtccaatcaa gtgcatattt
     1981 tttacagctt ctacttcatc atttactgga agattgtata gttcttcttt tctttcttct
     2041 agtgcctcta atctcccctc gtttcgctta cgtagaaaga ttgccactac ataagccaga
     2101 actaaaatga ctgcaattgc aaccattaaa taaattagtt gtccattaga catatcaaac
     2161 tcctttttta cttgaaacaa tcgtaacgat tatatcatat tttttagacc aagggaacta
     2221 cttctcccta ttttttagac atcaagtgta ctatagacag cattttcttc gataaactca
     2281 cgacgaggct ctactcgatc ccccatcaac atatcaaaga ttttatctgc ttctgcagca
     2341 tcatctacag aaactctagc catcaagcga tgttcgggat ccatggttgt ttcccacagc
     2401 tgatgatcgt ccatttcacc tagcccctta taacgctgaa tagtcggttt ggtacgacct
     2461 tcactataac gggctaaagc ttcttggagt ttgatttctt gatctgcacc cggctggata
     2521 tattctttaa tctcgcttcc aaccttgaca ccatagattg gtggttgggc aatataaaca
     2581 taaccagctt ctaggattgg tttcatataa cgataaatca aggttaaaag aagggtacga
     2641 atgtgggctc catcgacatc ggcatcggtc atcaaaacga gtttttggta acgggctttc
     2701 gaaacatcaa attctgcgcc aaatcctgtt cccatggctg tgaaaagact acgaatttct
     2761 tcgttagcta gaatcttatc catacttgct ttttcaacgt tcaaaatctt accgcgaatt
     2821 ggaaggatag cctgaaactc acggttacga ccagatttgg ctgatccacc agctgagtct
     2881 ccttcgacga tgaagagttc tgtttcagca gggttattag aagaacagtc tgctagtttc
     2941 cctggaaggt tggaaatttc caaaccagat tttttacgtg tgacttcacg cgcacgcttg
     3001 gcagccacac gagccttggc agccaaaatt cctttttcta cgatacgttt ggcaatctgt
     3061 ggattttcca tgaggaaatc ggagaaggct tcactgaaga ggcgattggt aatcttgacc
     3121 acttcgctat ttcccaattt ggtcttggtt tgtccttcaa actgtggatt tgggtgttta
     3181 actgagataa ctgcagttaa gccttcgcga acatcttccc ctgttaggtt gtcttcattg
     3241 tctttcagta acttattttt acgagcataa tcattgataa cacgtgtcaa ggctgtacgg
     3301 aaaccttgtt catgcgttcc accttcatgt gtatgaatat tattggcgaa actcatgaca
     3361 ttttcatggt aaccagttgt gtactgcatg gctacctcaa ctgtgatatc atccatctca
     3421 ccgtctgtat agattggtgt atcaaagatt acatccttgt tctcgttgat atattcaacg
     3481 taactagcaa tcccaccttc ataatgataa tgcttggttt gttccaaacc ttggcgctta
     3541 tcagtgatag aaatttgaag accgcgattt agaaaggcca actcttgaat ccgtttattt
     3601 aatttatcaa aatcaaagat tgttgtttca gtgaaaattt ctgggtccgg tgtgaagtga
     3661 accgttgttc cagttctatc tgtatcccca accacctcaa ggtctgcaac aacatgacca
     3721 cgacggtatt cttggtaatg aatcttaccg tttttatgga catgaacgtc taattgagtg
     3781 gaaagggcat taactactga cgaccccacc ccgtgaagac cacctgaaac cttgtatcca
     3841 ccaccgccga actttcctcc agcatgaagg actgtaaaga cggtctcaac agcaggacgg
     3901 cctgtttttt cctgaatatc gactgggata ccacgcccat catccacaac agtaatcgaa
     3961 tcatctggct caataaaaac ttgaatatgg ctggcaaatc ctgccaaggc ctcgtcaatt
     4021 gagttatcaa caatttccca gactagatgg tgaagacctt cttttgaggt tgatccaatg
     4081 tacatccctg gacgcatacg aacagcctct aagccctcta aaacttgaat ttgactggca
     4141 tcataatcct gtgcctgcag atttttgatt tcttctgtca tcttattcct ttttcttata
     4201 tgtctaatac ttgtcttaaa ttcacgatac tggtaaacaa gtgggtatca agtcctgcag
     4261 cttgacctgc ttcgatatca atcggccgat caccaatgac aagaccagag ctaatctgat
     4321 acttttctct taaataaagc atggattcgg gatttggctt tctcttaaag cctgagctag
     4381 aagtcaccac ttctgtaaaa taagctgcta tagaggtttt ttctaaaatt tccaaaacct
     4441 gatcatttcg atgagagacc aaaaaatgac ggccaccttg atttgaaatg acttccaata
     4501 ggtcagaaac tccttcaaat aaaatcgggt gttcaagctc tctggcttca ttttccttgt
     4561 acttttctaa aaaattctct aaattgggag cgaatgtctc aatcgcaaaa gaagtagaaa
     4621 cctttaaagc ttgatagaca ctgtcatggt cttgtgtgat accatacagt gccaatgttt
     4681 caacaaatgc agctgttgaa gtttcataat tatccagtaa agttccacct aaatcccaga
     4741 tgtaatcgtg atatttcata cccttcatta tagcattttt ttatgaaaaa agcgatgatt
     4801 tccctgagtt ttccacataa aaaacgagag aataactccc gttttactga tttttaccaa
     4861 agacatctcg atagagcatt cctgttcgta aactctctgc gtcccctcct agttgctcca
     4921 ccaactcgta ggcaaaggca agggctgttg aaggaccccg actggttgtc aactgaccat
     4981 ctaccactac tgtttccttg acgtagtgac catcaaggat ttgctcttga acgccgtcat
     5041 aacaagtgta tcgcttattt ttcaatatct ctgcttgatt gagggcaatt ggtgccgcac
     5101 aaatggctgc tagtttcttc ccttcttgct cgaagctttg caattcttga atcaaggtct
     5161 gattatcacg taaatgtgca gaaccaggca tacctccagg aagaacaatc atatcatagt
     5221 ctgataaatt tccatcaaag acatgatctg ctcttacttg gattgcatgc gaacccgtta
     5281 cttgctcttc aaaaccaacc atatcacatg tgatattggc tcgacgcaag acatctacaa
     5341 ctgtcaaggc ttcaatttct tcaaagccct gagctaacat aactgctact tttaccatga
     5401 ttttctcctt atttaatttg ttttaataca acctttttcc gtttgaatgg gacttttccg
     5461 ctcttttctt cagctagatt agtctggtaa ctcatcgata aaagcaaacc aacaccaatc
     5521 agattactga taatagctga tcccccttgc gaaatgaaag gcaagggaat ccccgtcaaa
     5581 ggaagtagtc cagtcacagc accgatattc tcaaagatgt ggaagagcaa catcataatc
     5641 aaacctgtgg aaatataagt gtagaactgg ttatttgatt taagagtaat cttcaacata
     5701 cggtaaatca acatgagata gagggcaata accaggacag agccaataaa gccaaaatct
     5761 tctgcaataa ccgtaaaaat catatctgac tctcgaactg ggataagcag attcgaagca
     5821 ttaaatccct gaccaaataa gccaccactc ccaatggcaa tctgcccttg agcctgctgg
     5881 taagtcgttg tttgggcaaa ctcaaaggga ttgagccaag ccaaaatccg attgatttgg
     5941 taggtcggca ttccaatctg gtgaagaaaa gctcgtccgt ccttgctaat aaagatagct
     6001 aagaaaccag caactcctgt tacagcagtc acaaatactg ggataataat tttccaagaa
     6061 acccctgata ataaaacgat tcctgagaaa atggctacaa aaaccaaagc cgtccccaag
     6121 tcactttgaa gtgctaaaag aactaggact ggaatggtaa agagaatcat ccagaaaatt
     6181 aacaaaaagt ccagcggaac cgtgcgtctc cattccttat gtttctttgt aaattggaca
     6241 atgacacgag ccaacatgag gatataagat atcttcataa attctgacgg ttggaatagg
     6301 gtaattccat ttattgatac ccagtttttg gcacccgttg atgcaactaa tcttggatta
     6361 taaaatacaa tcggcaagat cataagtccc aagcctaaaa tatatagaaa gggggtcacc
     6421 ttccaaagaa attctgtatt aaagagcatg accacaaaac caatcacaag ccccaaggca
     6481 atccaggcga cctgctgccc taaaatgggc aaaatattat tgggataatc atgactaacg
     6541 gctatataga tagccaccac accgatgacc agtagaaaaa atactggcaa gagcaaactg
     6601 taatcgactc ttgagtcgag agaacgtttc atatatacta accttatact ttcatacaat
     6661 actatttatc aaagttcatt aaaaaatcta tcaatagcct cgtcaacttc ggatcgagag
     6721 atggttttaa cagtcgcttc ttctgctaga gatactacta tttgtttgcc gtatcgtttt
     6781 ccgacgattc tcctatccaa aataagagtt aaggaacgtt ggtattcacg tcccatactt
     6841 cttcccaaag cctgttttaa acgaataatg gccattggca attgataatc ataaaaggca
     6901 tttttccctt cttgattcag ttcttgatta atctttttcg tcaagggttc ttgaggattt
     6961 tggaaaggaa gcctcggtac aacttgaatc acaaaaggat ggcttgaaaa atcaactccc
     7021 tcccagaaac ttgctgcacc aagcaagatt tgttgttcac ctttttcaaa gcgtttcttt
     7081 agctgatgaa catccccatt tttatactgg gccaagtggc taactgtaag taaatccgat
     7141 actgctagaa gcatgtcttt agcggtaaag agaaccaaaa tcggttgctg gaaagcttga
     7201 atttccacta gtaaagcagc tacctctctg gcatagactt ctaaggaggt ttctgttacc
     7261 agagggaaat ctttgaccat gaccacttct tgttcctgtt ttccccgaga ttcaatcttg
     7321 acaaatttgg cttcaggata gcctaaaagg tctgccaaag aaaccctctg actaatctca
     7381 agagtagccg atactcccaa gacttggcaa ctctcaggaa gtaaagagga cagaagagta
     7441 cggcatgatt ttgtagaaga aatctgaatt ttcttttgac tcgtttcagt tacttcaagc
     7501 cagtaatcac cttcagctgt aaaatagcga accagctcat caaagccttc tacttctaat
     7561 tctgaaaaat actgatggag attgtccaga gaatctaaga tatttttcct agatttacca
     7621 gactgaaatt gttctatcaa gtagagacac tcaaagcgaa tactttctag tatccgttgt
     7681 tgaaccctgt tttcttctcc tactaaagcc ttatcaatta aatcgataat agattgtata
     7741 tcgtaggtct cttgaagcag attttctaga gctaacaaaa tcttttggac ttcatcaata
     7801 atcagtaaac ggtcactgac aaattcagga ttatcttcaa gtctggtcac gagataggca
     7861 tgattagtca ctaaaagctt gcaagtctct gccctttctt gactacgttt ccaaaaatct
     7921 tccgtcacaa ataagctctg ggatgataaa ttcccatcat gacgaaggtc tgctagaaaa
     7981 tgttggtaac ggtagagttg cccgatttca tccaaatctc ctgtctctgt ctcagtaagc
     8041 cagaccaaga cttgcatttt aaagcgtcta aataagcgat tttcatcatt ttcctgcaag
     8101 gaatgataaa aggcatccaa cttcagataa ttttgtggtc cctttaagct atgaatatct
     8161 gtatggaaca cttccttgag gcgtttacct tcttcttcca tgatttgatt ttgaagaatc
     8221 tttgtcggaa cactaagaac aatttgtcgc tctttggatt gagataaagc gggtaagaga
     8281 tagccatagg ttttcccaat ccctgtcggc gcttgaatca gagagacagg ttcatctttc
     8341 aatagcaagc caacctcttt agcaaaactt tcttgttcct ccctcacttc aaggttcaac
     8401 agagaaatat ttttagaaaa gtcttgagat agttttcgtg gctccagaga agctgccgtt
     8461 ttcttaaaat acagaccttg aacttggacc aagtctggag aactcaggat agattggttg
     8521 cgataagttt cctcaataac caggtaggac tcatatagga gagcgtcagc catttccagc
     8581 aagcgttcca agagaccttt aggaagctgg gtcatctttt cccgtaaaaa aagaagtaat
     8641 tctgctgtag cttgggcatc tgaaagggct gtgtgtgcgt gtttaagagg aattcctaat
     8701 tctcgacaca aaatcggcaa gctatatttt tccagttcag ggaaaaagac ctgggccaat
     8761 tcgaccgtat caacacgagg gtttcttagc tcatagcctt caaaaaataa attttccgcc
     8821 aagagattag catcaaactg aacattatgg gctacaaaaa tcccatcctc caccaagtca
     8881 aatatttttc tggcaacttg cgaaaaatca ggtgcttgcg ccagacgttg gtctgtcaat
     8941 cctgtcagtt ctttgatatg agcatccaag ggttcatgtg gattgacatc cgtcgtatag
     9001 tgatcgacga tttctccgtc ctcaatcacg acaattccca cttggataat tttagcctta
     9061 ctacctgtgc tagttgcctc taaatccacc acaacatagc gattaccaat cgttttcatt
     9121 ataaaaaatt ataccaaaaa aagggccatt tggcacctgc aaacatagga taattttcaa
     9181 actcaagaac actacttttc ttaaaaatcc catcgaatag agcattctag cctgctgatt
     9241 tttgtaaaat agtgaagaaa tacgaaaaat tgagagaaga aatgtttgca tcttccttct
     9301 ctcaacgaat catgtatttt atctaaccat gtcaggatcg tagtcataaa atcctgtatc
     9361 aaggaaacgg tttttagggt gaagtttacg aacttcttca tccagcaaga aggcttgatc
     9421 atggctaaag ttgccctctt gaatcaagtt acgcgcttgg ataaagagtt ttgcaatctc
     9481 aacaaagttc tgaccaggag tgtagagccc ttctagtttc cagcgagtaa agccatgctc
     9541 caccaattct gttaatttga tcatcaaatc aaggtcattg ttggcaaaga tatgggtccc
     9601 atgattatct tcaaaaatgg aatagtggct ctctggatca cttggctcag ccaagaagag
     9661 gtcacgttta tgcgtctttt catcatcgat atgtgtaaag ttatagtagt tttgcaagag
     9721 tggacgttta gaatgatgga tgacgctagc accgtaaacc aaaacttcag caggaatttc
     9781 caaaatctct ggcattttga aaagttcagc tgatggaatt tcacgcgcca aaacagcctc
     9841 agatgcgcca gccttttgtc cccagaagtt aatctgacga ctgctagtta ccatggttga
     9901 agcatcgtag atggtcttaa atgaataacc atcgcggtta actacgtaaa agacgcctgc
     9961 atccccaatc gtaatatagt ctgtcttgat ttcttccaag aagtctaaga aaggcttgat
    10021 acggtccatc atatcttggt gcatgagagc attgaccgca acgatcaatt ccttaccagc
    10081 atcatgaacc aacttagcga tttcacgtaa ttggtcataa ctaaaggtcg ttggcagacg
    10141 aaggccaaaa tctttctcac cgacatagat acggtctacg ccagcttcga gtagttgttc
    10201 aacttgttca atactttcag cagttgctgt aatgacaatc ttttccataa gaaaaattat
    10261 accacatttc tccaaaatca tccatgcttt gaaaatgaaa agggacttta ttctttttgt
    10321 aacctttctg taataattct ctgccgaaaa aatgataaaa taggtatgta ctgttaagga
    10381 gagaattatg cccgtaagaa aattacaatc ctatgaggta gactatcaag aagaattaaa
    10441 ccagcagctt cctcattacc aagcttatac acctgaagcg caatctgatg ccaatctcaa
    10501 ggaaatccta ttttttatta atatcgctgt tttttgtatc tgtattgcta tctttagttt
    10561 tatcttttta gcattaaaat tatcaactgc tcttgccttt gccgcagcaa tcggattcag
    10621 cttacttgtt ttaaaagttc aacggtctat tatcaaacga aaacgtagaa gataaatcca
    10681 aaatatcgcc ccagttggag cgatattttt attttttctt tttagatggt gtctgaatgg
    10741 caatcttcac ttcaaagatt gttcccttgg gtttattatc tttgacagta acagttcctt
    10801 ttagagcatc tacaatttgc ttggctaggg ataatcctaa accaaaacca cctttttgcc
    10861 gggttctagc cttgtctact cgataaaaac ggtcaaaaat tttcttttta tcttctgtcg
    10921 aaataccgat tccattatca gaaacaagta aataaagatt gcgatcggtc gccgagataa
    10981 gaaaatcaat ttcaccatcc tcctcagtat acttgacggc attatcgaaa agaatggtca
    11041 tcagttgttt cagaagaagc tgatctgtga caattgttcg atggatacga ttttcaaaac
    11101 ggaagacacg attattttcc gaagcaatca tctcgtagtt tgtgaaagtt gtattaaaaa
    11161 agctagttgg aacttctgca agctccggct taatcccatc atctctccga gctaagttca
    11221 gcaagcttgt cgttaaaaaa cgcatatttc ggacttcttc caaactcgat gcaatgcttt
    11281 cgctcacatc cataatggta gcttctggct tacgaaaaag ggtctctaag cgattttgca
    11341 aaactgcgag tggagttcgt aactcatgac tggcattttc cacaaaagac tgttgcttct
    11401 gcatactctc aagcaggggc ctaacactga ccctagctag atagagactg gcaagtaaag
    11461 acaaaatcca gaaactagcc atcacgacca caatcaattg ctcatgcttt tgactagcct
    11521 gttccaactg actggtatta atcaagacag cagcatactt gatattggtt gaaaccgaac
    11581 taatattggt ctccatcaaa atcacacgat agatttcttc ctgcccatag ctattaaaaa
    11641 cctgaatctg gtagatatgt cctagttctt tcttttctaa cttaatctta tccaagccca
    11701 aaaatcgatt tccagaaaga agttgagtaa agtctttatc aaagagaatg acttccgtat
    11761 tggaactgac attaggtttt atttctactt tactagcgtc cgccctagca ttttctaaat
    11821 ctttaatctc ttctgttgcc ctatttatag ccagctgaat aactgcttga ggattttcac
    11881 tcagtccatg aagcttatcg tccaccgaag tataaagact cgaatgcatg acttgtaaaa
    11941 taatcagagt cattgtagaa aaaatcaggg tgaagacacc gaagttgcgg ataaaataac
    12001 taaagtcatc cgcataccat gtttttttaa gtttactgaa catcttttaa aagataccca
    12061 acactacgca aagtttgcaa attctctgca aaagtggttc cctttaattt cttacggact
    12121 tttgaaacat agacttcgac aaccgaaatc gttgtatcac tatcaaatcc ccatagacgg
    12181 tcaaaaatct gcgtcttagg taaaatcaca ttttgatttt gaaggaaata aactagtaaa
    12241 tcgaactctt tccccagcaa ttcgacagga gtatcttcaa ctttaacggt attggttgat
    12301 aaattaacca cgatattccc ataagtcaag gtgttttcat taaacttccc tgaacgtttg
    12361 agaagagcct gaatccgcat tttaagttct tctaggtaga aaggtttggt cagataatca
    12421 tccgctccca gttcaaatcc atgtcccttg tcatccaaac tttccttggc agtcataatc
    12481 agaactggtg tcgtaattcc cttttcacgc aattctttta agacttggaa accatttttt
    12541 tctggcaaca tcaaatccag caaaatcaag tcatagacac cactctcagc ttcgtagaga
    12601 ccttcttctc catcaaatac ctgcataaca tccgcaaaat cgtctaaaaa gtcaaatact
    12661 gaatttgaca gacctaggtc atcctcaacc aataagattt ttatcatgag aaactcctcc
    12721 ttattaaaac tattatacca aatttgcctt aaaaaaaact caactctctg cattttacat
    12781 gagatagctg agttttcttt ttattttagg cttatttatg catttccgta ttgaagaaca
    12841 actgcttcga ctgcagcttt ttcacggcta atcaagtcaa cacgcgctgc aatttccttg
    12901 attcccatac cgatgttacg gctaagagca aggtcagaaa gttgcggctc aaagaactcc
    12961 ttgtattccg ccaagcgttg ctgagtctta aatacatgag caggaaggat aacaaagcta
    13021 tcaaagctca tatctcctcc aagggctgcc ttaatccaag cccagttttc acgcgcccaa
    13081 gaccaagctg ttttctgagt tgcttgatga gctaggaatt ggtaatacca agcagacaag
    13141 tcctgtggtt tgaccacaaa tttgtccttc caagaagtaa tcaggttttg gatattatcc
    13201 gcatctgtac tgtatgcaag agctgctgcc aactggcgtt taaagacagc atctgttgcg
    13261 tgagtataag tatcaagata aagtgctaac aagtctttag tctcatgatg tttcatctca
    13321 ttaatcagaa cttgtgagcg aatagctgct gggagtcctg caagattctc cttgtgtgtt
    13381 gcgaagattt ggctagcgac ttgactagct tctgcatcat ttgagcgaat catcatcgaa
    13441 acagccagct gacgaaccaa ttcatcctca tctgattctc cgtctttagc ttcaaaacca
    13501 agacggtcat agttatgacg agccaattta gcaaccagtc ctttgaaggc tgtttcagca
    13561 tccgttcctt catcaataaa gcgctcaagg gctgaaatca cttgagaaac agctgaaacc
    13621 accagataag actcttcctt agcaagttta tcaagaactg gaagcaagtc tgcataagaa
    13681 atgtgccctg cctcagccaa caaacgacgt tcttgaacaa tttgcagttt gcttgtgtta
    13741 tcaagtgtct ctagctcagc aagaacagct tctaacaagt ctccttgata gtcggtaata
    13801 tagtgggcag tattttcagt gttgagacga agagctcctt cattttcagc aagaagagct
    13861 gcgtagccag ggatttcgat actttcagtt tcgagtgtat caggcaagcc tttccagttg
    13921 ctattgaggg gcaccaccca gagacggttc ttgtcttcgt tctcaccgat gaagaattgt
    13981 ttttgtgaaa tcttcaagac atcattttca actttaacag taagaactgg gtaaccaggc
    14041 tgttccaacc aagaatccat gaaggctgcg acatcacgtc ctgacgcttg accaagggca
    14101 tcccaaaggt cactaccaat ggtgttgctg tattggtgtt tttcaaagta ggcgtgcaaa
    14161 cctttagcaa aatcagcatc tcctagccaa cggcgaagca tgtgcatgag acggcttcct
    14221 ttggcataga cgatagcgcc gtcaaagagt gtattgattt catctggatg tttaacttcg
    14281 acgtggacag actgaacgcc atcagtagcg tcacgttcaa gagcaagagg tactccacct
    14341 gtttggaaat cttcaaagat attccagctt ggttcgatgg tatccacaca gacgtattcc
    14401 atcatattag cgaaactttc attgagccaa aggtcatccc accatttcat agtcacgagg
    14461 ttcccaaacc attggtgagc caattcatgg gccacaacaa gggcaacttg ttgacggcta
    14521 gcaaatgtag agttctcatc gacaaccaag taaacttcac ggtaggtcac aagaccccag
    14581 ttttccatag caccagctga gaagtcagga agggcgatgt ggagagattg aggaattggg
    14641 tacttaactc catagtaatc ttcgtaaaac tcgatagagc gaacagcgat atccagtgag
    14701 aaatcaagat ttgaaagtgg atgtgctttg gttgagtaga cacctaccag ggtaccattt
    14761 ttagttttag cggtcacccc ttgcaaatca ccagcaacaa aggccaacaa gtaagaagac
    14821 atgcgaggtg ttgtctcaaa cttccagata cctgtttcct tacggttttc aacatcgatt
    14881 tctggcatgt ttgacaaggc caattcacct tctgcttggt caaagcgaag agagaggtca
    14941 aaagttgctt tggcttcagg ctcatccaca catgggaaag cttcgcgcgc aaaatggctc
    15001 tcgaactgag tagacaagac ctccttcttg actccatcaa ctgtataata agaagggtaa
    15061 atccctgtca tgttgtctgt aattttacca gaaaaggcaa gaaccaattc aacttgacca
    15121 gcctcagcca attcgatatg aagggcttca ttgtcatggt caactgtaaa tggacgagct
    15181 tgacctgcaa cttctacaga ggtgatttcc aagtcttttt ggtggaggga gatgcggtca
    15241 ctctgtgctt gaccagtgat ggtcactttc ccagaaaaag tcttggtctc acgactcaaa
    15301 tctaaaaata aatcataatg ttcaggaaca aattgcttaa taaaatgttc aactgcttgc
    15361 atagttttct cctattctaa gtttaagagc tgctgctctt cttcaaacaa acttattata
    15421 tcatattttg cttgagaaaa aaggattgga cagcgatttc caaaactttc ttccttctaa
    15481 tagtctacag tgggtagacc ttgcgaaatt cttctaaaac aaccttgctt tcaggtgtaa
    15541 aagtcagccc tacttcaccc aaacagtctg tgaaaaagtc ctcatgaacc tggcgccaat
    15601 aggcaagtga tttgtctccc tcaccttcct taaaggcatg ttgcgcagaa acttgattga
    15661 agagttcaac agaaaccttt gtaatttcga caatgcagac agactgattt tgactatcta
    15721 aaatgacatc gaaggtccct acttggggaa gtggttcgtc ttctagtaca tagaggtcat
    15781 aggctgatgc tgttgctgtc ttttctcctt taaacaccaa atccgctaaa aggtctggtt
    15841 caactccaaa agcccaagca tcgatttcat ctccgatcaa aggattgatt tgcttgtatt
    15901 tattccacat ttcttgcggt atcatgggta ctcctttgta attttttact ttcttctttt
    15961 atgtgtttaa gatgatctgg atggtcaatc tctaaatcaa aaatctctgg aatagaactg
    16021 tagtggataa tgcacttgat acccaactga ttcatttttt gtatgaaaga agtattcaga
    16081 tagcctgcta cagcaaaatc aatcttgttc tttcttgctt tatcctgcat atctcttagc
    16141 atatctaaca ttattggact ttccatatca tgccattgac tgtttctcat agtcgcaaaa
    16201 acaaaggaag tcaaatcatt cattccaact acaatctttg aaatgcccgt ttccagtatc
    16261 ctatccaagt caaaatacgc tgacggtaat tcaatcatcg ttccgacttt cccagtaaag
    16321 ccatactgac gcaatactgt aatagcttgt tttaattggt cggcatcatt gacaaaagga
    16381 aagataagag atagattggg attggtttga taaacttctg taacgacatg tgcttcagcc
    16441 tgaaattcat ccaaacacgc cagtaaacgc ctggttcctc tatagccaaa caagggatgc
    16501 ccttcgtcaa aaaactctct agtccccact aaacaattgg cttctgtatt cgttaattca
    16561 gaaaaacgat accaaacttc ttcatctgag tacagggagc agatagtctc tagataatct
    16621 tttacaaatt gctgacaact tgctaatatg atgttttgat taagctctct caacaaatat
    16681 tccccacgaa tcatgccgac gtggtgaaat agttgaggat aaattttttc aagaattttt
    16741 tcgccactaa gggcaagttg atttctcatc attcaccttc caattcatgt aagaagtctt
    16801 gtccagttct ggaaatccta ataattcaga cttaaccttc aagactaatg gcgatgcatt
    16861 ttcttctgta atctcttgaa tatccatcca aatatatcca agtgaatcat tcgcaccatc
    16921 agacacagct tccgaagtcg taacttgagg tgcactctca ttcatttcaa catcatacaa
    16981 ggccatgaca tggtgaacca taaaatttgt taactcttct ctgacgaaaa catcgtagat
    17041 tcgaggatta gagtagcttc taacagtaaa tcccgtctct tccataactt ctctagtcag
    17101 cgtttccgtc agtccttcac caagttgctg actgcctcca ggtagatcat accgatgttg
    17161 ataagggcct ctcgtttttt caatgcagag taacttccca ttttctaagc aaacagcgta
    17221 gactccaaag tgttttttga tttccatcca actcctccta cttcaaagac cagccaccat
    17281 ctattgtcaa gatttgtcct tgcatggcgc tcgcttttcc acttgctaaa aaaagactaa
    17341 gctctgctat ttcctctggc tcaatccagc gcttgattgg ggtttcacta gccacccagt
    17401 cagccaaacc acctggttca aaatccgcag cggtcatagc tgtcttgact gctcctggag
    17461 cgataccaaa gacctgaatc ccagcttcag catagtctag agccaactgc ttggtgaagc
    17521 cagccaaggc atgcttggat gaagtatagg cgtgaccacc tccacctgct aggctagaag
    17581 caatggaaca catattgatg atgattccct ttttattttc cagcatttgt gtcaaataat
    17641 accgagtcaa ctcaacagga gtcatgtagt taatttcaaa aatctcttga atttcctgcg
    17701 cagtctgttc caacagtggt ttgtaagcat ccaaaactcc ggcagtatta cacaaaacat
    17761 ccacctgagg gcaccagtca aaaataggtt ccaagtccaa ggtcaaatct ctctgtaaaa
    17821 agtgaaaatc accctctaag agtggctttt caccttggtc aactccataa acttgatagc
    17881 ccttctctaa aaagaggcga gcttgagcca atccgatccc tgaactcact cctgtaatga
    17941 gtacacgttt agtcatgcac ttctacccaa tccgttgcca aaacatcaca agctgtcggg
    18001 ctccacatgg aaaaaccttc tccttctcca gacacgttga ttaagaaata aggtgtcact
    18061 tcaagtgcaa gcccattttg ctcgatggta tcaaagagtt ggacatagtt ttcagcacct
    18121 ccccaaccag ttcgtacata ttttttctta gcctttaagc caggtagaat ttcttcaaat
    18181 gtcatgtttt tctcctttaa tgtcaataat tctccccttc attataacaa aaaaaccgct
    18241 ttaaaacggc tttttgactg tgatttattt acatcttctt ctacttacgg caaattattc
    18301 cctgcagcaa gataaatttc ataccattct tttcttgtta agctaaagtt tgccgcttgg
    18361 ctaacttctc tcaagtgctt aggatttgtg gtacctacaa ctgcctgcat ttttgctgga
    18421 taacgcaata tccaagaaat ggcaatagtt gaagaggtta ctccatattt aatagctaaa
    18481 cgatcaagta cttgatttaa agcttgaaat ttctcatttc caacaaagtt ccctttaaaa
    18541 tacccgaatt gcaagacaga ccatgcttga atgaccacat cgtgtaattt gcaatattca
    18601 aaaatgctgc catctcgcat agctgcttga ctatcttcca tattaacatg aaaagctgat
    18661 tcaaatcctg gagtaaaagc cgcactcaat tgtagctgat taacagctaa cggctgcttg
    18721 acatcttttt taagcaactc catcatcata ggattttgat tagaaactcc aaaatctcga
    18781 actttacctt gtttataaag gagatcaaag gcttctgcta cttggtcaga ttccatcaaa
    18841 gcatctggtc gatgaaggag caagctatct agatgatcaa tcttcaatct ttgcaaaata
    18901 ccgtctactg attttataat atagtcctta gaaaaatcaa aataggtaaa ttcttcaatg
    18961 cgaatgccac atttggactg aatccacatc ttttctctta aatctggacg attttttagg
    19021 acaagaccta acagttcttc acaacgacca cgaccataaa tatcagccaa gtcgaaggca
    19081 ttgattccaa cagaaagtgc tgtttctaca agctcttcaa cttcttttac agacttatct
    19141 tttattctca tcattccgag aacaatttct gataattctt tgtcatcttg accaagagtt
    19201 atgtatctca tcaaattttt ctcctttaat ttctaacatt cttcccttca ttataacaaa
    19261 aaaccgcttt gcaacggctt tttgactata cttcactcca ttttatcttc ttaaacccac
    19321 ggaacaagac aaagattcca ataaagagga cagctaaagg aataactttt gtaaggaaaa
    19381 catttgaaat tcccatccac tcataataac ggagcagaga acccaccaca agatgggcaa
    19441 taatcatact gacaaatgga cgaaagaccg cttctttcca attccaaata ccgataacta
    19501 gcgaaatcgt aaagacagac aaactatccc agggagccgg aatataaaag gctccttctt
    19561 gtatgaagct tgccattcct acatatccta aaacaactag aagaactata gtcccaacaa
    19621 caatgtaagt gccaattttc attttaggag aatcttggac taaacttctt cgtaaaattg
    19681 tggccacaag tccaaatcca atcagaaaaa taagaagttg ccctaaaaat gtgagcaaat
    19741 tgactgttaa gagaggacct ttagaaaaat cacttagtag ttgataataa cgtaataccg
    19801 ccaggacaag aattggcgtc aaaagggact ctttgataga actgcgaggt gctcccttga
    19861 gaatctcttt cattattttt ttaggattct tacctagata atcctctgca ctcatgccat
    19921 ctcgttctgc ttctgagaaa tctagcatca tcaaatagat ctgctctctg agatagtctt
    19981 catcatagag aaatccagca agattaaaac tttcccacaa ctcctcaaaa tacttttgat
    20041 tctcctcaga aaactcatgt agcaaagcgc ttgtttcttc gtaatacttc attttcttca
    20101 tggtttaacc cccattctta atcccttcta ctttttgact caaatcgtcc cattgttgcc
    20161 aaaagactga gacacgctct tctccttctt tcattaatga aaaatacttc cgatctggac
    20221 catctggcga cgggcgcatg tcgcctctta tccattgatt tttttctaac ttttgcaaca
    20281 aaggataaat agttcctgga acgatagtat caaatccagc ctctcgcaaa gtctgaacca
    20341 actcataacc ataccgctct ttttgaccaa tcatatccaa gacacaacct tcaagaacac
    20401 cttttaatag ctgagtttct ttcatcactt ctcccttcta atctattttg taatacctac
    20461 tagtaacttc acctatagta tatcacttct acactagttt gtaaagcata atagttaata
    20521 ctcttcgaaa atctcttcaa accacgtcag cgtcgcccta ccgtatgtat ggttactgac
    20581 ttcgtcagtt tcatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct
    20641 agtttgctct ttgattttca ttgagtataa ataaaaaaac agaactagtc tgaactagtc
    20701 ctgtctactt ttacccaatc acacttccat ttggtacagc tggatcaact gtgagaaggg
    20761 ttaatttgcc atcatgttca gctgatagaa tcataccctg gctgacatat tttttcatca
    20821 ttttacgtgg tttgaggtta gcaacgattt gaactttctt gccgaccaat tcttgttcat
    20881 ttggatagta ttttgcaatt cctgaaagaa tctgacgatc ttctccatca ccagcatcca
    20941 agcggaattg aagcaactta tctgaacctt ctactttaga cacttctttg acttctgcga
    21001 cacggatttc aaccttgtca aagtcttcaa acttgatttc atccttgttt agtttgagct
    21061 caacttcgtc cggattccat tctttttcga ctgctggttt attgccttcc atttgttcct
    21121 tgatataggc gatttcttct tccatattta gacgtggaaa gataggtgtt cctttggcaa
    21181 ctacagtcac atctgctggg aagtcagcca aactcaagtt ttcaagacta gaaacttctt
    21241 ccaaaccaag ttgagtcaaa actgcacgac tagtttccat cataaatggt tcaatcaagt
    21301 gagcaactac acgaatgctg gctgccaagt ggctcatgac acttgccaat tggtcacgaa
    21361 gagcttcatc cttggccaag acccatggtg cggtctcatc gatgtattta ttggtacgag
    21421 agatcagagt ccagactgct tcaagcgcac gtggatagtc aactgcttcc atgtgtgtat
    21481 ggaagtctgc gattgattgt tctgcaacct cagcaagaac atgatcaaat tcagtcacac
    21541 cttctacata ggcagggatt tgtccatcaa agtacttatt aatcatggaa accgtacggt
    21601 taaggaggtt cccaaggtca ttagccaatt catagttgat acggccgaca tagtcttcag
    21661 gagtaaaggt tccgtctgaa ccaactggaa ggttacgcat gaggtagtaa cgaagtggat
    21721 ctagtccata acgctctacc aacatttcag ggtaaacgac attccctttt gacttagaca
    21781 tttttccgtc tttcatgaca aaccaaccat gggcaatcaa acgatcaggt aatttaacat
    21841 ccaacatcat aagaaggatt ggccagtaga tagagtggaa gcgaaggata tcttttccta
    21901 ccatatggaa gactgttcca ttccagaact tgtcaaagtt accatgttcg tcttgagcgt
    21961 agccaagagc tgtcgcatag ttaagaaggg catcaatcca aacgtagaca acgtgttttg
    22021 gatttgatgg gacaggcact ccccatgtaa aggttgtacg agataccgcc aaatcttcca
    22081 agcctggctc gatgaagttg cgtagcattt cattaaggcg accatctggc gtgataaatt
    22141 caggatgagc tttgaaaaat tcgaccaaac ggtcttggta tttgctaagg cgaaggaagt
    22201 atgattcttc agaaacccat tcaacctcat gacctgatgg agcaatacca ccagtcacat
    22261 ttccagcttc atcacggaaa acttctgcca gctggctttc tgtaaagaat tcttcgtctg
    22321 atactgaata ccaaccagag tattcaccca agtagatatc atcttgagca agtaagcgtt
    22381 caaagacctg tgcgacaact ttttcatggt agtcatcggt tgtacggata aatttatcgt
    22441 atgagatatc tagtaattgc cagagttctt taactccaac cgccattcca tcaacatagg
    22501 cttgaggtgt aataccagct tcttccgctt tctgctggat tttctgacca tgttcatcaa
    22561 gacctgtcag ataaaataca tcgtagccca tcaggcgttt gtaacgtgct aggacatcac
    22621 atgcgatagt tgtgtaggca gaaccgatat gaagtttccc agatggatag taaatcggcg
    22681 ttgtaatata aaaatttttt tcagacataa tttttccttt ccaggcaaat gaaacctgtt
    22741 tttctaacac ttcattatat cacattttta atgaatttcg atagggaaat ccatacaaaa
    22801 acaagataga cgagtgtcca tcttgttgat ctcattcata acgaagggct tcaattggat
    22861 caagtttcga tgccttgttg gctggcaaga ctccaaaaat cataccaaca ctagccgaaa
    22921 ctgcaagact aaatagggca actgggattg atactccaac ttctatacct tctattaaac
    22981 cttgcagtaa caaacctgct aaggcagtta aaccacttgc aattgtcaag ccaattaagc
    23041 cacctaacaa ggtcaaaatc atggattcaa tcaaaaactg aattaaaata ttggcacgtg
    23101 ttgcacccaa agccttacga agaccaatct cacgagtgcg ctctgtcacc gaaaccagca
    23161 tgatgttcat gacaccagtt cctccaacaa agagagaaat ccctgcgatg gaactaataa
    23221 tcgtcgtcat aaaactaaac gattgttgaa tttctgcaaa tacaacggac tcatctgcca
    23281 cctggtattc tccctgttgt aagcctgcaa gctctgtcat ttttcgtgcc agttctggac
    23341 ccagagttgg ggttaaactg gtatcattca ctcgaaagac aatattagct atttcatcta
    23401 cattaaaatt cgcagcaagg gagatattgg tagtaatagg caagccacca aacccatata
    23461 tttttgatct tttagcctcc ggactagtat aaaccccaat gacccggtaa ctaaatccat
    23521 tgacttctac aaccttgtta atagcctctt gaggagattc aaataaacta atggacaatt
    23581 cctcatctag caaaatgaca cttgcaaact ctttgaaatc ttgctctctc agactacgac
    23641 ctgcaataat ttcattctta acagcgtcca tgtaagttct gtttccacct gtcaaattag
    23701 cattctcaac ctttttatct tgataggtca agatggcatt cgttgaattg gttacatagt
    23761 aactatccac tcccttcagt ttagctgcct cttgaaccca ggattcttgc ggttttggcg
    23821 gttcaacagg aacttcctct tcctttccag aaaccgtaaa agctgattgt ttctgagtaa
    23881 aagacccatc tttacttttt ttaggagaga aaaagacgct aatatttttc tgagatttag
    23941 tcatatcttt attgacttga cgagataggg aatcacccaa agccataatc acaacaactg
    24001 atgaaacacc gataataatc ccaatcatag taagcaaaga acgcatcttg tgagccatga
    24061 tagatgaaaa ggcaaatttc agattctgca tcttagtttt cctcctttcc taactgagca
    24121 ctgtcagacg aaatgacccc atcccgaatg acaatctgac gtttggcata ggcagcaatc
    24181 tcaggctcat gcgttaccat gataatggtt tttccttctt tattcaaatc aaccaataat
    24241 tgcataattt ggttacctgt tttggtatcc aaggctcctg tcggttcatc cgctaggata
    24301 atagaaggat tgtttaccaa ggcacgcgca atggctacac gttgcttttg accaccagat
    24361 aattctgaag gtaaatggtg actacgttct gtcaattcaa ccttgtctaa atattcctca
    24421 gccaacttgc gacgttttga agacgaaact cctgcgtaaa tcaagggcaa ttctacattt
    24481 tgcagagcat tgagcttcga tagaagaaag aactgctgaa agacaaaacc gatttgttgg
    24541 ttacggacct tagccagttg tttttcacca agcccagcca cttcttgacc ttcaagataa
    24601 tattctccac tggttggtgt atccaacatg ccaatcgtat tcatcagagt ggacttacca
    24661 gacccagatg gtcccatgat ggctacaaat tcaccctcat tcacttctag attgatattt
    24721 ttgagaacct gcaattcttg gtcaccatta cggtagcttc tgaagatatt ttttagacta
    24781 attagttgct tcatcagcct tcacctcttt tccttcttcc aaggaagatg ttggattact
    24841 gatgacctta gcaccgttcg ttaaaccaga agtgatttct tgattttctg cgtcagcatt
    24901 tcccaatgaa acctcaactt ttttagcctt ttgttgttca tccacaatcc agacataatt
    24961 tttactatca tccattacta gactgctaac aggaacaaga atagccttag ttttgctttt
    25021 aacctcaatg ttgacagaaa aaccttgttt caaatcacca acctcgcctg tcacatcaat
    25081 agtataaggg tatttagaac ctgtattatt cccggctgct ggactagctg cttcaccatt
    25141 gtttttagga tagtcagaaa tatagcttaa tttcccagtc cattttttat caggatacac
    25201 tttagaagta aagcttactt cttgacctac agaaaggttg gctagattgt actcagacaa
    25261 ttctcccttg acttgtaaat tttcattgct gacaatatga accataactt ggctcgcccc
    25321 tgttggagat ttagaaacat tgctattgac ttcgactaca gttccctcta gggtactgag
    25381 aacagttgtt gcatccaatt gactttgagc cttacttaat tgcgccgcag catctgcacg
    25441 cgcatcacgg gcatcaccca attgagcgtc aatagaagca acagaatttc cagccactgg
    25501 agttgggctt tgcaccgttg catcttctcc tcctactggc gctggtaact gtggagccgg
    25561 agctgaagcg gcttcatttc gtgcttgatt gagttcattg atatgacgat ctgccttagc
    25621 tactgctcga ctagctgaat cataggccgc ctgcgcttct gaactactgt acttgactaa
    25681 agcctgccct tcgctgacct tatcgcccac agaaacaagg atttcatcta aatcaccctt
    25741 actagcatca aaataaacat attgttcatt ttttgctgtt actgtccctg acaataaaac
    25801 agaggatgcc acgcttcctt ccttggcaac aacaagatga gtaggctcat cttttagagc
    25861 agtctgagaa ggttgtctaa agagtaaaat ccccccggca cccaatacaa ctacactcgc
    25921 agcaccgatt gctgcataca gttgccactt tttagcttta ccattctttt tcttcataat
    25981 gaaactcctt ttctttttta caatactttg ctattatacc aaatttccct ccagcaaaca
    26041 atgcagttca gatggaaata atggcagttc aggattaaac aatcgttcgg aattttgctt
    26101 ttctattgta ctagatatat aatacactat cttgacttat ttggcaagct tttttgcaat
    26161 tttttgtgcg tagcagattt ttgcaatcaa atcaaaaaaa gaataaaata taactatcaa
    26221 aaaagacact ctactattta aaagattaca aaggagtttt caatgagaga atatgatatc
    26281 attgctatcg gtggaggtag cggaggaatc gctaccatga accgtgctgg tgaacatgga
    26341 gccaaagcag ccgttattga ggaaaagaaa ttaggtggaa cctgtgtcaa cgtcggttgt
    26401 gttcctaaaa aaatcatgtg gtacggggcg caaatcgctg agactttcca tcaatttgga
    26461 gaagactacg gctttaagac tactgatctt aactttaact ttgcaaccct acgtcgcaat
    26521 cgtgaagcct acattgatcg cgctcgttct tcttatgatg gtagttttaa acgcaacggt
    26581 gtagacttga ttgaaggtca tgctgaattt gtagattctc atactgtaag cgtaaatggt
    26641 gaactgattc gtgctaaaca tatcgtgatt gctacaggtg cccatccaag tattcctaat
    26701 attcctggtg ctgagctagg tggctcttct gatgatgtat ttgcctggga agaacttcca
    26761 gagtcaattg ccattctagg cgctggttat atcgccgttg aattagctgg cgtactccac
    26821 acttttggtg tcaagacaga tctctttgtt cgccgcgatc gtcctttacg tggttttgat
    26881 tcctacatcg ttgaaggttt ggtcaaggaa atggaaagaa caaacttacc acttcacact
    26941 cacaaagtcc ctgtcaagtt agaaaaaact actgacggca ttaccattca tttcgaagat
    27001 ggtactagtc acacagctag ccaagttatc tgggctacag gtcgccgtcc aaacgttaag
    27061 ggcttgcaac ttgaaaaagc tggagtgact ctgaacgaac gtggctttat ccaagtggat
    27121 gaataccaaa atactgttgt tgagggaatc tatgctctag gtgatgtaac gggcgagaaa
    27181 gaactgactc cagttgcaat caaggccgga cgtaccctat ctgaacgtct ctttaacgga
    27241 aaaactactg caaaaatgga ttactcaact attccaactg ttgtcttttc acaccctgct
    27301 atcggaactg ttggtttgac agaagagcaa gctattaaag aatacggtca agaccaaatc
    27361 aaggtttata aatcaagctt tgcatctatg tactctgctt gcactcgcaa ccgtcaagaa
    27421 tcccgtttca aactcataac agctggttca gaagaaaaag ttgtcggact tcatggaatt
    27481 ggctacggcg ttgatgaaat gattcaggga tttgccgttg ctatcaaaat gggagcaacc
    27541 aaggctgact ttgatgcaac tgtggcaatt cacccaactg catctgaaga atttgtaacc
    27601 atgcgttaat cgaaacaaaa gaagctgata taaatatgtc tgcttctttt ttaatgattt
    27661 tcgaatcaac aaaaaaatta tccaacttga ctagtcacga aaatcggctg ttacagtttt
    27721 tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata atagttacta
    27781 tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta tccctgctat
    27841 tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac ctgttccctt
    27901 cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga gagaggctgt
    27961 actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct ttgcaggagg
    28021 tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt tttatctcgt
    28081 ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta agatttttct
    28141 tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct tgcatttcct
    28201 agctggaatg gcatttgaaa aagctcttgt tgtgggggtt cttcccttta tcattccaga
    28261 ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac gccttaaaaa
    28321 tcaggcttac tttactaact aaaaaaggat accgagttat catgactcaa tatccttttt
    28381 tttattttga aaacttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
    28441 gctgctcaaa acactgtttt gaggttgtag atgaaactga cgaagtcagt aaccatacgg
    28501 caaggcaaag ctgatgcggt ttgaagagat tttcgaagag tattagttgc ctttaaaggc
    28561 atccaccatc gtttgaaatt cttcatttga gagagtaatc cctttgccca ttttagtatg
    28621 gtctggactc caagcacgaa tatcaaactt tgcaggggca ccattaaagc tcacacggtt
    28681 aatttccttg gtccaacctt tttcgttttc agaaagagtc aacaagtgct cttcgatttc
    28741 aaatgtaaat tctgccattt tcttctcctt ttttagtttc attagtttat tcgtaaaatc
    28801 ttgtagattt taggaaaatt ttatataata ttgatataaa agaagggagg ccaatatgag
    28861 acataaattc cagcaagttc tagataaaat acatgatttt ttaaatggac atgaccaacc
    28921 tgaccagact gaaaccaact cccttacagc cactattgaa gaggctatcc agaaacaaac
    28981 cgctgttcac cttatcttgt ctgagacaag ctttacaggt gatatcatca aatatgatca
    29041 gcaaggccag caaattatcg tgaaaaattt tgccaaaaat gtgagccgga ttatccgtat
    29101 aagcgatatt caacgcctgc gatttgtccc ctcaactgtc caaacagccc aaaaaaatag
    29161 atttaagaaa gagtgagatg tagttgcttc atcccactct tttttcttag cgaatttgtt
    29221 caaaatgtaa atgaactgcg atatgatctc cataaccact tctttccaag tcacgttgta
    29281 aacgatagga aatgtagtgt tctgcaatgg taatgtaacc tgcgcccaat aaacgatgtt
    29341 caaccataga ttgaatcata ctgatagtcg cacgttccac cttggcttct tgtaaatcca
    29401 aaactacctt cttagtgact tgagcaagat tttgacgcaa atcatctgtc aaaacataaa
    29461 cagtttgggc tgccttcaag atggcttggt aaatcttatc tggattaaat tcagcaattt
    29521 cgccattacg tttgattact tgcataggtt tctcctttat tctttgtttt ctttgatttc
    29581 tgccagcatt ttttcttctt ctactgtcag ttgataatgt tcaagtaaat ccggtctgcg
    29641 ctcgtaggtt ttctttaaac tctcgtacaa tcgccactga cgaatctttt catggtggcc
    29701 actcatcaat acatctggca cgaccatgcc tcgataatca tagggacgtg tgtactgagg
    29761 atattctaaa agacctgaag aaaaactatc atcttggtgg ctagactcct tgccaatcac
    29821 ttctggaatc aggcgaactg tagcatcaat catggtcata gctgccaatt ctccaccagt
    29881 gaggacatag tcgcctaggg aaatctcatc tgttaccaag gtcttaatgc gctcatcata
    29941 accctcatag tgcccacaga taaagattag ctcttcctct tgagccaaat cttcagcata
    30001 agcctgatca aactgctttc cagcaggatc gaggagaata acgcgcggat ttttcttttc
    30061 aatagcatca aaggaatcga aaataggttg tgctctgagc aacatgccct gaccgcctcc
    30121 gtagggctca tcatctacat gacgggcctt ttcagcattt tctcgaaaat tatgatactg
    30181 gatatccaag agcccttttt ctcgagcctt tccaacgatt gagtgctcca gtggagaaaa
    30241 catctctgga aagagggtta aaatatcaat cttcatcgtc taacccttct aagatttcca
    30301 catcgacccg tttatttgga atatcaacat tgagaaccac tggtgggata taaggtaaaa
    30361 gcaaatcacg tttgcctttt cgtttgacca cccagacatc attagcacct ggttgcagga
    30421 tttccttgat ggttccaacc aagctatcac cctcatagac ttccaaaccg ataatctcgt
    30481 gatagtaaaa ttcaccatcg tctaggtcat tcaaatcttc ctcagcgacc ttgagactgt
    30541 atcccttgta cttttcgata gtattgatat ggtacatatc tttgaattta ataatgtcaa
    30601 agttcttctg tttacggtgg ctagcgatgg tcactgtttg gacaaactga tctttttcat
    30661 caaacaaagt cagctcagct ccttttttaa accgttcttc tgcaaaatcc gtcacagaca
    30721 atactcgcat ctcaccctgt aatccctgcg tattaacgat tttcccaaca ttaaagtagt
    30781 tcatcttgtc tcctgtaatc tcctttttcc atcttattct gacaattctc gaataatagc
    30841 cgcaattttt tccgattctg accattgtaa ataatggtga ttccttccta aaatgagttt
    30901 agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag tctgacaaaa
    30961 aataaataca gggacatgag attctatcga caaattctca aaatcttcct cagtaatctc
    31021 tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt cttgcattaa
    31081 ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt tcttaaaata
    31141 aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg gataaggatt
    31201 ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta ctaaagtctg
    31261 acacttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac tatgtgcaca
    31321 aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat ctgcaagatt
    31381 atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg gaaaatcaat
    31441 tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat tttcataact
    31501 tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt tataagtaac
    31561 agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat ccactcattc
    31621 tatataatga attattaaaa atccttatcc tttattttat cacgttccaa agattttctc
    31681 aagttggagg aaggggacaa tatctctact ttcccttcaa gaatccttcc aaatcatgtt
    31741 tatgttggta attaacggct gcggttttgt ctttctcaaa gatggttcta gttaggtcaa
    31801 tatgcttgat agcagcaata gcgacggtgt agtgaatgat attagccagt tctatggcag
    31861 gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa aacctcggct
    31921 acttctccga cttcctccac taacttcata aagagacctt catcagtccg agactgctgt
    31981 taatgttcga gtaagtagtc ttggaattgc ctaaacgttc aatcttttat agta
//
LOCUS       DAVLZG010000020        30506 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLZG010000020 DAVLZG010000000
VERSION     DAVLZG010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.020"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(1..297)
                     /locus_tag="VYO72_000881"
     CDS             complement(1..297)
                     /locus_tag="VYO72_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707282.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VYO72_000882"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VYO72_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1707283.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(2690..2950)
                     /locus_tag="VYO72_000883"
     CDS             complement(2690..2950)
                     /locus_tag="VYO72_000883"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707284.1"
                     /translation="MSDIKVNIPGECLYDKVFVLSFIIYNISINLNIVNGIFYIQAKK
                     DSITFEWKAKEQTRKLAIDSSKPCFEVVDIVKGNKNRTNRSG"
     gene            complement(3571..4797)
                     /locus_tag="VYO72_000884"
     CDS             complement(3571..4797)
                     /locus_tag="VYO72_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1707285.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAASRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="VYO72_000885"
     CDS             complement(4840..5532)
                     /locus_tag="VYO72_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1707286.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="VYO72_000886"
     CDS             complement(5705..7456)
                     /locus_tag="VYO72_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707287.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATMVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGV
                     TYHKMYSLQAGAMADTL"
     gene            complement(7446..9191)
                     /locus_tag="VYO72_000887"
     CDS             complement(7446..9191)
                     /locus_tag="VYO72_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707288.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9397..9693)
                     /locus_tag="VYO72_000888"
     CDS             complement(9397..9693)
                     /locus_tag="VYO72_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1707289.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9846..10303)
                     /locus_tag="VYO72_000889"
                     /pseudo
     CDS             complement(9846..10303)
                     /locus_tag="VYO72_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10437..11264
                     /gene="xth"
                     /locus_tag="VYO72_000890"
     CDS             10437..11264
                     /gene="xth"
                     /locus_tag="VYO72_000890"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1707290.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11276..11413
                     /locus_tag="VYO72_000891"
     CDS             11276..11413
                     /locus_tag="VYO72_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1707291.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLLKSV
                     N"
     gene            11524..11652
                     /locus_tag="VYO72_000892"
     CDS             11524..11652
                     /locus_tag="VYO72_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1707292.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12035..12130
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12530..13111
                     /locus_tag="VYO72_000893"
     CDS             12530..13111
                     /locus_tag="VYO72_000893"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1707293.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13111..14373
                     /locus_tag="VYO72_000894"
     CDS             13111..14373
                     /locus_tag="VYO72_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1707294.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTRFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14424..14885)
                     /locus_tag="VYO72_000895"
     CDS             complement(14424..14885)
                     /locus_tag="VYO72_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV1707295.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14882..15646)
                     /locus_tag="VYO72_000896"
     CDS             complement(14882..15646)
                     /locus_tag="VYO72_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV1707296.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15827..16231)
                     /locus_tag="VYO72_000897"
     CDS             complement(15827..16231)
                     /locus_tag="VYO72_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1707297.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16301..17782)
                     /locus_tag="VYO72_000898"
     CDS             complement(16301..17782)
                     /locus_tag="VYO72_000898"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1707298.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17801..18979)
                     /locus_tag="VYO72_000899"
     CDS             complement(17801..18979)
                     /locus_tag="VYO72_000899"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1707299.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19144..20151
                     /gene="galR"
                     /locus_tag="VYO72_000900"
     CDS             19144..20151
                     /gene="galR"
                     /locus_tag="VYO72_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1707300.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20197..21234)
                     /locus_tag="VYO72_000901"
     CDS             complement(20197..21234)
                     /locus_tag="VYO72_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1707301.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21235..21588)
                     /locus_tag="VYO72_000902"
     CDS             complement(21235..21588)
                     /locus_tag="VYO72_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1707302.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21832..22722)
                     /locus_tag="VYO72_000903"
     CDS             complement(21832..22722)
                     /locus_tag="VYO72_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1707303.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22855..23391
                     /locus_tag="VYO72_000904"
     CDS             22855..23391
                     /locus_tag="VYO72_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1707304.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23557..24363)
                     /locus_tag="VYO72_000905"
     CDS             complement(23557..24363)
                     /locus_tag="VYO72_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1707305.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24708..26228)
                     /locus_tag="VYO72_000906"
     CDS             complement(24708..26228)
                     /locus_tag="VYO72_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1707306.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLNGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(26221..26949)
                     /locus_tag="VYO72_000907"
     CDS             complement(26221..26949)
                     /locus_tag="VYO72_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707307.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(26964..27728)
                     /locus_tag="VYO72_000908"
     CDS             complement(26964..27728)
                     /locus_tag="VYO72_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1707308.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27732..28175)
                     /locus_tag="VYO72_000909"
     CDS             complement(27732..28175)
                     /locus_tag="VYO72_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1707309.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28857..29153)
                     /locus_tag="VYO72_000910"
     CDS             complement(28857..29153)
                     /locus_tag="VYO72_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1707310.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29175..30239)
                     /gene="pepA"
                     /locus_tag="VYO72_000911"
     CDS             complement(29175..30239)
                     /gene="pepA"
                     /locus_tag="VYO72_000911"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1707311.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPYVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
BASE COUNT         9001 a         6897 c         5508 g         9100 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttaccc ccgaatatac
      841 tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatgctatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac tatcccgatc
     2701 gatttgtcct attcttattt ccttttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttattgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttaccttaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat atttgcgtta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaaa gacgctagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct ataccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 gcaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaagctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaactgca tggaatgaga aggaagtaaa gtcagcgata gaaccagaag gttgtccttt
     4261 ataaatagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactggaata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccactacttc
     4741 agtaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac
     4861 ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt
     4921 atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 ctccgtcatt tgactgataa ttgtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aatccctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tgcggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacgaaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 tttgctatcc aacttgatcc aaatgctcaa gatgagaaag atgggagagg tcagaaccag
     5401 taagaccaag gccaaaaccc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtatcggcc atggcccctg cctgcaaact atacatcttg tgataggtta
     5761 ctcccagagc caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcatct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaagct ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgttgccca gtagagaagc tcgaaccacg ctcggaaaca ggggagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actggtttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgcaagacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatat gagaaacaca
     6421 catgttcaaa acggatattg ccttcttgga ctttggcttg cccattttct tgaagaggtt
     6481 cataggtcct ctcgtctatc agggcaaaga cacgacctgc agaaaccata gccgtttgca
     6541 gagttgaaaa gttttgcgtc acctcaatca aggggtcaaa aaggcggttg atgtactgga
     6601 taaaggcata catggtcccg accgttatcc cgatagaaaa accacggtag ccaaagtagg
     6661 ccatcaagac tgcatagcct agaagtttca gcaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcgtaga ccaagtgttc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaagg cctgaataat cctgattccc tcgatattct
     6841 ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg attttcactg
     6901 acttttttcg atagagattg accaaaagga aaatcaaagg aagaaagagc aagactaaag
     6961 ccgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa
     7201 agagaagatt gcctacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt aacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacgagggg tatgacactt ttaatgacca tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtcaggag tccataaggc ttgagataag acatcaagcg cttcaataca gcccattgtt
     7441 cttgtttatt ctgcatcttc ttctcctttc atttccaact gctgagactg gtaggtttgg
     7501 gcataccagc catccatcgc tagcaagtct tcgtgcgtgc ctcgttcgat aatttgacca
     7561 ttttgtagaa ctaaaataaa atctgcatgg acaacagcac tgaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagtcgcaa agagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatag tacccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag aggaaactca
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaaaccg atggccagaa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg aaccatcaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gtataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgagtta attgccccga tgtgatggca
     9061 tcaatgactc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaatcc cgactagata acggcgtttt tctaacttga aaaaccacca gagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agaaattttc gaagagtaca agaccccagg tttttcttat tcataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtct gtcacaactg gatacttagg attttcatct cccatttgca caacgatgag
     9601 ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttatgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg
     9781 aacattgttg ttgagctatt tgaaagtcaa gatcagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaatttggt tcctttttta tcatggtatg ccttgaaagc
    10201 aaaaaaaaac tgtcacagct aatagaacaa tcccaaagcc aaccatgata ccattttgct
    10261 gaccgatttg gctgagtaca tagtcataag agtagaattt catgtatttt cactcccttt
    10321 cataaaatca ttcttaatta taaacgaaag agagtaattt ttcaaaccat acgttgggga
    10381 aatagatctt tttttggtat aataaaatct ataatctgaa tgaaaaaggt aactttatga
    10441 aacttatctc atggaatatt gattccctaa acgctgccct aactagtgac tcagctcgtg
    10501 ccaaattgtc ccaagaagtc ctacaaacct tggtcgctga aaatgctgat atcattgcta
    10561 tccaagaaac caagctttct gccaaaggac ctacaaagaa acacgtggaa attttagaag
    10621 aactcttccc aggctacgaa aacacgtggc gctcttccca agagcctgcc cgtaaaggct
    10681 atgctggaac catgttcctt tataagaaag aacttacacc cactgtcact ttcccagaaa
    10741 tcggtgcccc ttctaccatg gacttggaag gccgcatcat cactctagaa tttgatgcat
    10801 ttttcgtaac ccaagtttac actccaaacg ctggtgacgg tctcaaacgc ttggaagaac
    10861 gccaagtctg ggatgttaaa tatgctgagt atttggctga actagacaaa gaaaaaccag
    10921 tccttgcgac cggtgactac aacgtagccc acaatgaaat cgaccttgca aatcctgcta
    10981 gcaaccgccg ttcacctgga tttactgacg aagaacgtgc tggatttacc aaccttttgg
    11041 caactggatt tacagacacc ttccgccatg ttcatggcga tgttcctgaa cgctacactt
    11101 ggtgggcaca acgcagcaaa acttctaaaa tcaacaatac aggctggaga atcgactact
    11161 ggctcacaag taaccgtatc gctgacaagg tcactaaatc tgatatgatt gactcaggtg
    11221 ctcgccaaga ccatacaccg attgtcttgg aaattgactt gtaaggattt tctatatgga
    11281 ctacaatgcg gtcattcccg agttgcttgt atcgaatatc gaacagtccc ggtccttcta
    11341 ctgtggttta ctgggtttta ggattgaata ccaacgtcca gaagaaaact ttctcttgaa
    11401 gagtgtcaac taatgttaga ggagggaaca aaggatcaac tagctgaact gacctacccc
    11461 tttggtcgtg gagtcaatct ctcctttggc ataaaggatg ttccaaaact ctattaaaga
    11521 gtgatgaagg caaactatcc tatttatcgt cccttgacca aaagaaagtt tcgtgtcagt
    11581 gatccctata tctatcctca taaatttgca gttttggatc cagatggcta ttttttaaga
    11641 tttagcgagt agaataataa aaattgggaa aagtctttaa agttagaaaa aggcatattg
    11701 tcaggtgtct aaaaacttga tagtatgcct tttatgatgg aaaaatcttc taatactctt
    11761 cgaaaatctc ttcaagccac gtcaacgtcg ccttaccgta ggtatatgat actgactctg
    11821 tcaattctat ccacaacctc aaaacagtgt tttgaggttg tggatagctt cctagtttgc
    11881 tctttgattt tcatttagta taaatgttag cttacaatgg agtttttgtt caccccctct
    11941 tctgtttgtt cgttttttaa atcaaaacac taacaaaata gttgatttat aaagttattt
    12001 agtgtaaaat aaaaacattg gctcaagcct atttaaaatt gaatatcgtt ttacttgttt
    12061 atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa cacctaacaa taagtaagtc
    12121 agcagtgaga tatggtcgtt tttgccatgc ctatttgggg gacttactta gagattaagt
    12181 aggtcctttt tgaatatttt taatatttcc cttaattagt gcggacggga ggtgaaatta
    12241 tcctgtgaat aatttcagga attcagggaa tttcatccct aatttttgag cccctagctc
    12301 tttcatttct aggcttaggc taaaatagtt ccccgaacta ttttactctc aaaaatcccg
    12361 tcatagacaa taacaagatt attgtctatg ataccactac atcgggaaat atttgataag
    12421 actattacga gcgaagcgag tcttatcaaa tatatagtat tagcaaaagg gatcactata
    12481 gaaacatttc aacaacaagt aaattagctt ttagacttta ggaggtctta tgaaattatt
    12541 agaagatcgc atcctcaagg atgggcatat cttgggtgat aacatcctca aggtagattc
    12601 ctttttaacc caccaagttg actttagctt gatgcgagag attggtaagg tttttgcgga
    12661 aaaatttgct gctgccggca ttaccaaggt cgtaaccatt gaagcgtcgg gtattgcccc
    12721 agccgttttt acagctgaag ccttaaacgt tcccatgatt ttcgccaaaa aagctaagaa
    12781 catcaccatg aacgaaggca tcttaactgc tcaagtctac tcctttacca agcaggtgac
    12841 cagcactgtt tctatcgctg gaaaattcct ctcaccagag gacaaggttt tgattatcga
    12901 cgatttcctt gctaatggcc aagctgctaa aggcttgatt caaatcatcg aacaggccgg
    12961 tgccacagtc caagctatcg gtatcgtgat tgagaaatcc ttccaagatg gtcgtgattt
    13021 gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgc ttggatcgtt ttgaaaatgg
    13081 tcaggtcgta tttaaggagg cagatctcta atgcaaactc aagaaaaaca ctcgcaagca
    13141 gccgttctgg gcttgcagca cttactagcc atgtactcag gatctatcct ggttcccatc
    13201 atgattgcga cagcccttgg ctattcagct gagcagttga cctacctgat ttctacagat
    13261 atcttcatgt gtggggtggc aaccttcctc caactccaac tcaacaaata ctttgggatt
    13321 ggactcccag tcgttcttgg agttgcattc cagtcggtcg ctcccttgat tatgattggg
    13381 caaagccatg gtagtggcgc tatgtttggt gcccttatcg catctgggat ttacgtggtt
    13441 cttgtttcag gcatcttctc aaaagtagcc aatctcttcc catctatcgt aacaggatct
    13501 gttattacca cgattggttt aaccttgatc cctgtcgcta ttggaaatat gggaaataac
    13561 gttccagagc caactggtca aagtctcttg cttgcagcta ttactgttct gattatcctc
    13621 ttgatcaaca tctttaccaa aggatttatc aagtctatct ctattttgat tggtctggtt
    13681 gttggaactg ccattgctgc tactatgggc ttggtggact tctctcctgt tgcggtagct
    13741 ccacttgtcc atgtcccaac tccactctac tttgggatgc caacctttga aatctcatct
    13801 attgtcatga tgtgtattat cgcaacggtg tctatggttg agtcaactgg tgtttatcta
    13861 gccttgtctg atatcacaaa agatccactc gacagcacgc gccttcgcaa cggttaccgc
    13921 gcagaaggtt tggccgtact tctcggagga atctttaaca ccttccctta caccagattt
    13981 tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa aacgcctgcc aatctactac
    14041 gcagctggtt tcctggttct ccttggactg cttcctaagt ttggtgccct tgcccaaatc
    14101 attccaagct ccgtcctcgg cggtgccatg ctggtgatgt ttggttttgt atctattcaa
    14161 gggatgcaaa tcctcgcccg agttgacttt gctaacaatg aacacaactt ccttatcgca
    14221 gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta atctctttgt cagcatgccg
    14281 acagccttcc aaatgttctt ctcaaacgga atcgtcgtag ccagcctact cgccattgtc
    14341 ctcaatgccg tattaaatca taaaaagaaa taagaaaaag aggtgcgagc ctcttttttg
    14401 tgtgacaaaa taaaaacatc tacctattca tatatgctag tgtcatagtc ctgaaaatca
    14461 tctgcatcaa gaacaatttc acaactctta tacttttctc ttacaagtcg ttcggcttca
    14521 tctggatttt cagcctctat acttactaaa cgtgataaag tttctgtaat ttctactgta
    14581 tactttttca gttttagatt gctttccaat aattcaccta ttaacaataa tctatgatag
    14641 gagctatgta gccactctgg caatttatct cctacttccc acccatattt ttccttcatc
    14701 aaagctagtt gtttttcgtc accaaatttc atattttcag ataaccatct cacacaatcg
    14761 ggatctgata aggtacagac gattaaactt aggttatcgt aacggctttc agtttcataa
    14821 tcaggccaga tgacttttaa gaaatcatac acctcttctg atgcaacaag ttgtttcgtt
    14881 ttcataattt ccgatacttt cctctacctt taaattctat tatttctttg tctcttaata
    14941 tttgaagctg ttgcctaatc ttttctttga tatgattgtt cttaacaaag atatttttta
    15001 ggtcactttc aaaacgatac atatcttcaa gggtaaattc tgaaccctct atcttatcta
    15061 tacaatttag aatttctatt gtccaacctc ttgatgacag agagctcttc cttaaaaata
    15121 aaccttgctt aaattctttt gtaacttttt ctggatctct aacttgtcca tcttgcacaa
    15181 gaaatatcct tcctttagaa ggtacttgtg ataaatcaat gttacaacca atccaacctg
    15241 ctcgtctagc agttggtgca agtggttttc tttgaataat cgatttcggt gtaacaaatt
    15301 gcttcggaag gacaagaaag ttatttacct caaaattttt tgtgtaagtt aaaaaaaaga
    15361 aattaggatt attatctgcc tgcacacgct tcatcatcgt tgcataagca ccatcattga
    15421 ttgttgatga aaaatttcct tttttgctct ttagttcaaa ctcctcacta caatgattac
    15481 agtaaaaatc tgctacaggc cgattatttt caaaatgatt taagggattg ttcccacaat
    15541 tagggcaata agactgacga taaacccaat cctccgttaa gatacgtgcc ttttggctat
    15601 tacttttata ggtttctact aattctaaat taaagtgtaa ttccatttaa aaattcctca
    15661 ctaatatgag aactcactcg atataagcaa ttaaaatcta ctataactag tataccacat
    15721 atatgtacct attacatttg tatttcatca ctctctttta tatttccttc taacatatct
    15781 cataaattaa aaatgagtga gataaattta tcccactcac ctttctttat atacttaccc
    15841 gtctttcctc agacctttgg cctgtgacaa acatggtaaa ggttgcttta cagacatttc
    15901 tgccctcttg attggtgata tccacatcca tcacacaggt tgtacgacct tgatggacac
    15961 attctccttt aatggtcaat acatcgtcga gttttcctgc cttaaggtag ttgatagagg
    16021 attggagtgt caccccatca agtcccagcg agataaccac caaaccactg atttggtcac
    16081 atagcgtgaa tagatagcca ccatgggcat tgccatagta gttgagcgac gagttcacta
    16141 ctttggtcgt caccacaacg tgaccatctc tcattttttc aatttcgtaa ttttcaaagg
    16201 cagatatagc gtcaaaatga aagtctttca tcgtttcctc ctgatatttc aaacgacact
    16261 atgatactac tttttatagg actgtgcaag gagaaagctc ctagtctagt aaaattccga
    16321 catgttccac aaagcgcata aaggctgtct gcccttgttc tgtctgcttg tagactcctg
    16381 catcctcaag tacacgcgca aagatagcac ccacagagtc cttgacgatt gcaagggctt
    16441 tttctttatc cgttaggtct ggatgttggg atttgagttg gtctgcccac tcctgatgat
    16501 aatcggcaac tgtaacagct tctcctacaa gatagctcgc gacttgctcc acttcttctt
    16561 tcagacgtgg tggcaagatt gccaagccca tgacctcaat caagccgata ttttccttct
    16621 tgatatgttg gacatccttg tggggatgat agatgccatc aggatgctct gctgaagtct
    16681 gattgtctcg caagaccaag tccaactcaa actgtccatc acgcttacgc gctattggtg
    16741 tgatggtgtg atgcggtgtc ccgtctgtct ctgctaaaat ctgcacacta gaatctgaat
    16801 actgacgcca ttcctggaaa atcttatcag ctaagttaat caaatcctct ttggaatccg
    16861 aagtcaagcg taggacagac attggccact tgataattcc agccttgacc tgctcaaaac
    16921 cagcaaatcg gaaggtcttt tgcaagggag ccaattccat aggaaatacg tgacggcctc
    16981 cctgataatg atcgtgagtt agaatagagc cccccacaat cggcaggtcg gcattagatc
    17041 cagcaaaata tcctggaaac tgctctacga tagccaacag acgttcaaaa ctctgacgac
    17101 taatggccat gggacgatgc tggccatcta aaaagataca atgctcatta aagtaagcat
    17161 agggcgaata ctggaacccc cattcctgac caaccatttc aaaacggata atccggtggt
    17221 tgctgcgagc tgggtggttg acccgaccat ggtaaccctc attctctaaa caaagttgac
    17281 actgaggata attactagct tgcaccaact tggctaccgc aatctctttc ggatcctttt
    17341 caggcttaga gagattgatg gtaatttcaa gttctccata atcagatgga acacgataag
    17401 cgatattttt agcaatggcc ttgagtttga tgtaatcatt tttctgactg agttgataaa
    17461 aatcctctat cgcttgctca ggagagtgga cataggcttc ccagaagtca cgattgacct
    17521 gactcggata aggagtcacc aagtccatca gttcagtacc aaggatttca cgcgcagtct
    17581 gactatcctc aatcatctct aatcgaacgg cttcctcaac tagctggtcc ttgaggtcaa
    17641 tcaatttatc cagattggtc tcaacttcca aaacaccttc tcccactcgt gccaaaacac
    17701 ggttggtcag gtagattcga tccatttcct caaatgaact ttcagaaatg acatgtgtta
    17761 caaatttatc tactaagatc actatagagc ctccttttga ctagtcaagg acgcgagtgc
    17821 cacctgcaac ttcagcgata tagaagcttg gagcgtatcc aactacttcc tcgtagtgtt
    17881 tgcctacagc ttccttaaag gcctcaacag tatctttttg aaccaaggca atggcacagc
    17941 caccaaaacc agcccctgtc atacgagcac cgagaactcc ttcttgtgcc caagctgtgt
    18001 gaacaagagt atccaattcc aaaccagtta cttcataatc atgctccaga gaaacgtgtg
    18061 acgcattcat caaacgacca aatgtttcca aatcacctgc ttgaagggct gcttgagctt
    18121 taagggtacg ttggttttca agcacagcat ggcgagcacg tttcaaacga ttttcatctt
    18181 taatcaaata gctatattgg tcaacggccc actcgtccaa ttcacccagg gtctgaatat
    18241 ccaaggcaac ttgcaattct tccactgctt tttcacactc agcacgacgt tcattgtatt
    18301 tagagtccgc caattcacgg cgtttgttgg tgttcatgat aacaacgaca ttgtccttca
    18361 aatcaagtgg caccaagtcg tattctaaag tattggtatc taagtaaata gcacgttggt
    18421 cagcccccat accaatagca aactggtcca tgataccaga gttgactccg ataaagttgt
    18481 tttctgtttg ttttccgatt ttaaccaaat ccaaacggtc tagttttaaa tcaaagagat
    18541 gctctgccac gactcctgtc aagagctcca aggatgctga agaagacaaa ccagcaccat
    18601 ttgggatatt cccataaaca taaaaatcaa aacctttgtc aatcacgtgc ccagcttctt
    18661 gcaagaaatg aagaacccct tttggataat tggtccagtt gtgctctttt tcaaacttga
    18721 ggtcagcgag aggcacttcg ataatgccct tgtcctcaaa gttagctgag tagaaacgca
    18781 agacttggtc gtcacgctta cgagctgcac cgtaagttcc caaggaaata gcagcaggaa
    18841 aaacgtgccc accgttgtag tctgtgtgtt caccaatcaa attaatacgg cctggtgaaa
    18901 agaaggtttg gtctgcttct tgaccaaaaa cagcaagaaa gtctttgcga aggacttcag
    18961 tagtaagatg ttgtgccata tgaattctcc tttgactgtc cgttaagcca tcttaacgtg
    19021 taatcgtttt ctttctattg tatccaagga atttcccaag gtcaatcctt tttactaaaa
    19081 ttttactaaa atatcagtaa aaagaagaaa aatatgatat actaacctaa tcaaggagga
    19141 tttatggcta ccttaaaaga cattgcacag ctagcctctg tctcaatcgc gaccgtatcc
    19201 cgtgtcctca accgcgacca gagcctatct gttacagaag aaaccagaca ccgtatttta
    19261 accgttgctg aagagctagg ctacaccaaa cacctcaaga caggcgagtc ccacaagccc
    19321 aagcaaaaga ttgccattat ccaatgggtc agcgaacaag gggagctaga cgacctctac
    19381 tactaccaga ttcgcctagg aatagaaaaa agagcccaag agttggacta cgatatcttg
    19441 cgctatttta atgaccatcc ttttacctta agcgaggaag tgattgggat tctctgcatc
    19501 ggaaaattta gccgagctca gatttctgcc tttgaagaat accaaaagcc tcttgtattt
    19561 ctagacagcg atacactttc cctgggacat acctgtatta tcacggattt ttacactgct
    19621 atgaaacagg ttgtcgatta tttcctcagt caagggatgg accgcatcgg gattctaaca
    19681 gggcttgagg aaacaacaga ccaagaagaa atcattcagg acaagcgtct agaaaacttc
    19741 aaaaactaca gtcaagcgag gggaatctat catgatgaac tggtctttca aggaagattt
    19801 actgcccagt ctggctatga cttaatgaag gaggccattc agagcttggg agaccaactt
    19861 ccgccagcat ttttcgcagc cagcgatagt ttagctatcg gtgctctccg tgccctccaa
    19921 gaagctggaa tcagcctgcc agatcgcgtc agcctcattt cattcaacga caccagtctg
    19981 accaaacagg tctatcctcc cctctctagt attacagttt atactgaaga aatggggcga
    20041 gcaggtatgg atattcttaa caaggaagtc ctccacggtc gcaaaattcc tagcctgacc
    20101 atgctgggaa ccagactgac attaagagaa agtaccctaa atcaagaata ggataacata
    20161 aaaaacgaat agagttctaa aactcctatt cgttttttat tcgattacaa tcatagactt
    20221 aatggtctta cgttcatcca tatctttgta ggcttggtcg atatcttcca gtttataact
    20281 tgaagtaaag acgcgacctg gattgatatc accatcaagg acggctttta gtaaaaattg
    20341 cttatcgtat gttgtagcag aagctgcccc acctgctaca gagatatttt gcataaatgt
    20401 cgaaccaaga gcacgattat tatagtgtgg gactcctaca aagcccatac gccctccatt
    20461 atgaagaaca cctagcgcct gttctatagc agcctccgta ccaacacatt caagtgctgc
    20521 gtctgctcct ccaccgagga tttcacgcac cttggtaatt ccttcttgac cacgttctgc
    20581 aacaacagct gtcgcacctg actccatagc catcttttga cggtcttcat gacggctcat
    20641 aaggataatt tgtgatgctc cacgcatctt agccgcgatg acagcacatt gaccaacagc
    20701 cccatcaccg ataacaacaa ccttgtcccc tttttgaaca tttgcaacac gcgccgcatg
    20761 atagcctgtc ggcatgacat ctgcaagagt caaaagggac ttgagcatcc cttctgtata
    20821 gtcagaaggt tgaccaggga ttttaaccag cgcccagttt gcatagtgga agcgaatata
    20881 ttctgcctga aaatcacccc ccaaattatt gccaatatga ttgtcgcaag aaccgtcaaa
    20941 tccagcaaga caggcatcac actcaccaca tccatgtgta aaagggacaa tcacaaaatc
    21001 acctggtttc accgtcgtaa tggcttcccc agcttcttca acaatcccaa tcgcttcgtg
    21061 tccactattt ttgtgtccag ctttcgtttc tggattacgg tacctccata aatctgaacc
    21121 acaaacgcac gcacgaacca cacgaataat cacatcatcc gcttctatta tttgcggacg
    21181 ttcaatgcta gcaagtccaa cctgacctgc ctttgtatat actgctgatt tcatttaaaa
    21241 ttttccttcc ttataaagtt taattttgag atttaaacga tttaaagctg tctgtagctg
    21301 agacaagcgc tcctctaatt tttgcttttc ctcttctaaa ataccaagcc tctcctctct
    21361 cgtttcatct cccttttggt agagcgacat atagtcaact aaactatcta cagagacacc
    21421 cgccgaacga aaacacttaa taaattccag cgcttcgata tcctgatctt gaaaatcacg
    21481 aatcccagta gcagtacgag taatcggtgg cacaagacca acccgttcat aataccgaat
    21541 cgtatccgct gaaattccca acaaatcact ggcagattta atattcacac gctaacctcc
    21601 tctcatttca ttcactgaat tcacgctatt ctaactcact tatcttatta tataactttg
    21661 agttgactcc aagtcaagca ttttgtatct aatcgaaaaa tttttatcat taacaatcat
    21721 atatctggag tttatacaat gctcttctct taccaatttt tgaaatattt aaataataaa
    21781 gaaattactc tattccaaat aagatagtac ccaagtattt ttcacttttt tctaatgttg
    21841 atgctcataa ctccgttcca agtcacacac ctttcgctta tgggtttggt gagtttctag
    21901 gtcagcatca atttcaatgg taatattttg aaaaccacaa tcttttagga aaattcgaat
    21961 agactcttta caagtttcca tatgttccat ttcttttaga caaacatgga caatggcatt
    22021 tttttccaaa gcatccatag tccagagatt aagctgatta aggctggcca cattgtccaa
    22081 tcgctccagg ccactcttta cttgcttgat atcaagacct tctggcacag catccaagaa
    22141 aatcttgagt gtagaccaaa aacgtggaag ggcttttgaa agaataaaga aagaaatgac
    22201 aagggacaaa agaggatcta ggatatacca gtccgtaaat cgaagaacaa tcgccatcag
    22261 gataacagct acccacccta gcgtatcttc cagaaaatgc agactcagaa tagactcatt
    22321 ctttgtcttt cccttaccaa ccaccagact cgctaacaga ttgatagtaa tcgcaataat
    22381 tcctaaccag agaatcccct catcattgac tggttgcgga tgcaaaatct tcgtgacatt
    22441 ttccaaaatg actagaacag agcccgttac gagaatcaca gctgttacca aggctcctag
    22501 caggctaaac cgcttatagc ccaaggtgta ctgattgtct tcttcacgat tggagattgt
    22561 ttctagaaaa gctgatattc caattgcaat cgcatctccc aagtcatgca cagagtcagc
    22621 aagaacagcg ctagaaccaa atactccacc tgcaataaac tcaacaatgg cataagtcaa
    22681 atttaagaaa aaagccaccc aaacagcata ttttgccttc atatttctca ttcctttgtt
    22741 ataatagatt tatgaacacc ttgttcatta tcattatcca ctaaaactca aagaaaggat
    22801 agaagcaaaa cgtcagcttt attcagttct gaacaatttg cctcaagtgt ccatatgact
    22861 aacattgacc gccgtatcag caaaaccaaa aaagccatct atcaagcttt tatacaactt
    22921 ttgaatgcta agggctacga ggccactact gttcaggata tcattgatct cgcagatgtg
    22981 ggacgatcca ccttttactg tcactatgag agtaaggagc ttcttctgga ccagctctgc
    23041 cgctacctct tccatcatct ttttgaaaga gagcaagcca tttcaaccga ggactacctc
    23101 gcccacctct ttctgcattt tcataaaaac caagaccata tcaccagtct gctattttcc
    23161 aaaaatgact acttcctccg tcaactccat aaagagctag aacaccatgt ctattccgtg
    23221 ctagctgata atttaaaaga agcccaccct aatctgccta cttcttacct ccaacacttg
    23281 gtcatgtcca actttatcga gacattgacc tggtggctca aaaaaggtca agatttcaca
    23341 gaccaggaag ttgtccaatt ttatctagac cttctcattc ctaaaaattg aatatagagt
    23401 aaagctcagt tgtcttattt ctagattact gagtttttta tcttttcaac aacaaaagag
    23461 gacccgccga tcctcttttt catactataa atccttgatt atcaactata tctgttttaa
    23521 tcgaaatctc aaaacagcac tttcaaacat cttttcctag ttaagtaaat cagtattctg
    23581 cttagctgcc ttgctccatt gataccaacc aactagactg ttaatgagat aaattagata
    23641 tttcccttga atttgcaggc tttctcccca ccagagatag attgaaaaga cattggtagc
    23701 cgcccagaat atccactgtt cacggtaaac agctgtcatg aggatttgcc ctaccccatt
    23761 ggttgcatct gtgattgaat cacgataggg acgattggca ccaatagact gataaatgaa
    23821 gccaaaggcc aaccaccaaa gcacactaat ggaaagatac tttgtccagc ccttgccgtc
    23881 cagtttacgc gcgacaaact cctgcttttc cttcttaaac tgtgcctgat aaatccaaac
    23941 tagaagtcca attggctgca tgactgtgaa gtaaagtgtc gtcagcacct caccataaaa
    24001 gcctttctgt agggccaaaa taaggtaaat aacagagtta atcaagccaa aaagataatt
    24061 acttgctcga ccttccgata caaagattac acagataatc cctgtcaagc tacaaatcat
    24121 cccaatccag tcaacaatac gatgttcgta aaccaactcc agccagagag gaaaacttcc
    24181 taaaaccagc aaataaatcc actgggcaaa actacgatgg gcaaagaggt catcccagat
    24241 agccttcata gttcctgaaa atcctaaatc agccatagcc gcaaccatac gacggtaacc
    24301 acctgacatt tcacctaggg ttgttttgat attttcaatt ttcttttgca aataagtatg
    24361 catcatttct ccttttgttt ttaaagagcc gtgtctggat agactttcgg acgcaacgct
    24421 ctattagata atgaactgcc tatacacaag atttctaacc ttagtcgaca tgagctgaaa
    24481 cctcttattt gttaagtagt tcacaaaata ttatacacct attttatgaa tagtcaactg
    24541 tctttacagt aaaattttag aaaatcatga aaattttctc tttctttcca ttttaagtga
    24601 cattcagtca ttctcacatc aaaaaagccc agacgaaatt gtctgagcat tcttttatct
    24661 agtcgtttaa ggaagttgag ttcagtatgt ttaaagtctc tgtcccatca tttcttcaac
    24721 aaaccttgtt cttggagaaa ctccttggct acttgctctg ctgacttgcc ttcaacaccg
    24781 acttggtagt tgagctggct catctggttt tctgtaatct taccagccaa tgtattaaga
    24841 actctttcca actctggatg tttcttgaga agagcttctt tcatgagtgg agccccttga
    24901 taaggtggga agagttgctt gtcatcttcc aagacctgta aatcataacg ctccaattcc
    24961 gcatcagtcg aataggcatc cgtgatttga atatcccctg actgaattgc ctgataacga
    25021 agagctggct gcatagtcgc cacattgaga ttgagaccat acattgattg caagccctta
    25081 tttccatctt cacggtcgtt aaactcaagc gtaaagcctg ccttcagctg cccttccact
    25141 tttttcaaat ccgaaatggt cttcaagcca tattcttgag caatcttttt cggaacagct
    25201 acagcatagg tattttgata agacataggt ttgagatagg ctagatgatc ctgcttggca
    25261 atgccatcac gcgccacttg ataaacctgc tctggctcat gactcacctt gggtgatggt
    25321 tgaagcaaac tttcagtcac cgtaccggta aattcaggat aaatgtcaat atcacctttt
    25381 ttcagagctt cataaaggaa acttgtcgtc ccaaaattcg gtttaacagt cgcagtcatg
    25441 ctggtatttt cttcaatcag caatttatac atattagcca aaatttctgg ttctgggcct
    25501 attttcccag caataatcaa gttttccttc tctttttgag ccaaaagggc tggactataa
    25561 gacagaccca gtaataaagc caccaaggca aaaccagaga aaatcgtccg caatttcgct
    25621 ttttccatta cttttagtag gaagttaaag gcaatagcta gcactgcaga agaaagtgcc
    25681 ccaatcaaaa tcagactggc attattacgg tcaattccca aaaggataaa ggaacctagt
    25741 ccccctgccc caatcaaggt cgccaaggta gccgtaccga taatcaagac cgctgccgtc
    25801 cgaattccag acatgataac aggcatggca agtggaattt caaacttctt gagacgctcc
    25861 catctggtca tcccaaaggc aatcccagcc tcttgcagac tcggatcaat tccattcagc
    25921 ccagtaatag tattttgtaa aatcggaaaa atcgcataaa tcactagagc tgtcaatgcc
    25981 ggtaaagtcc caattcccat caaagggata aagagcccca acaaggccag agacgggatg
    26041 gtctggaaaa tacctgcaat ctgcaagacc cagtcggcca gcttctcatg atagcgaaga
    26101 taaacagcca agggaatcgc aagcaaaata gctagtaaca aggtcaaaag tgacaactgc
    26161 aaatgttgag atagggctgt caaccaatca ccaaaacgat cctgaaaagt tgcaattaaa
    26221 ttagtcatga atactacctc caaacaagtc tgcaacaaag tctgttgcag gagcttttaa
    26281 aatagtctca ggattcgaca cctgacgaat ctctccatcc tgcaagacag caatacgatc
    26341 tgccaacttt aaggcttcat ccgtatcatg agtcacaaaa atcgttgtca tcccaaactc
    26401 tttatgtaat tcttttgtca gaacctgcaa ctgttttctc gaaatagcat ccaaggctga
    26461 aaagggttca tccatgagga gaatcttggg ctgaccaatc atagctcgga caataccgac
    26521 ccgttgctgt tctccaccag atagctcact tggaagtcga tgcccatact cagctactgg
    26581 taaaccaacc ttagccaaaa gctcttctgt tttttgagca atttcttcct tagtccaacc
    26641 cttcatttca ggaatgagag caatattttc ctcaactgtt agattgggaa agagagcaat
    26701 agcctgtaaa acatatccag tagaaagacg aagttcacgc tcatcatagt ctttgatgcg
    26761 cttcccatcc atataaatat ttccatcagt tggttccaaa agacggttaa tcatcttgag
    26821 catggtcgtc ttacctgacc cagaaggccc tactaaaacc ataaattccc catcctcaat
    26881 ctgtaagttg acatctctca agacatcctt ttctgtgtag cgcagtgcta catttttgta
    26941 ttcaatcatt ctttgtcctc aatttaaaac ttccctcgat tagtcaagtc ttctacctta
    27001 ggcatgactt ccttattatc ccaatgctcc acaattttcc cgttctctaa acggaagata
    27061 tcgtactggg cataagcaac gccatcaatc tgagtctgac catagctaac cacatagttt
    27121 ccttgtccta agagttggaa aacaaagtca aaagtgacac tatattcagc cacatagttt
    27181 ttataagcag cacttccttg tccaatctca tgattatgct gaatcaaatc gtctgccaca
    27241 taatcactcc actgctctag ctccccattt tggaaaattt ctgtcaagaa acggcgaacc
    27301 aactttttat tttctgcttt cttatccaaa tccttgattt caaaatctcc aaaaatttga
    27361 tctagttggt cattttcagg tgttcgatag tagtcaatga catcccaatg ctcaacaata
    27421 cgaccattct catccgcacg aaaagtatcc gtcgtcaccc attgagcttc tccaccattc
    27481 agatattgat gaacatgaac aaagaccaga ttgccatcct caatggtgcg gacaatctta
    27541 atctgacgct ctggatgacg ctcaaagaaa tctgcaaaga aggctgcaaa tccttctttc
    27601 ccgtcaggaa cacctgtcga atgttggata taggtatccc ctacagactg ggcttgagcc
    27661 tcagcaactc gtccgtcttg aatggcatgg atgtataggt tgtgagcatt tttcacttgt
    27721 tgtgacatat tctaaacctc atttcccttc tctttcaaat tcgccaaaat tctttcttga
    27781 aaaccttcaa attggtgaat ttcttcctct gaaaatcctt tgtaaaagat agtatccaat
    27841 ttctgactga cacgatgccc cacttctttc tgggacttgc ctaactccgt taaaactaaa
    27901 tacttcttac gcttgtcttt tccacacgga ctaacaatta caagcttttg ttcctctagc
    27961 ttttttatca tagtcgtcag cgtattattc gcaagcccag tcgcaagcgc gatatctgtc
    28021 gcagttgcgc agccagtttc actattccat aaaaccgcta aaatcttgcc ctgttcaccc
    28081 ctataaagag cctcaggatc ttgactcagt aacttttgaa aaatccgccc attcaacaaa
    28141 cgaatatgat gggctagcaa atgaccatct ttcataacac ctccaattta tttcgatatc
    28201 gaaatgaata aaacaattgt aacactcatc gttctaactg tcaactattt cgatttagaa
    28261 ataatttttg ataattatcc acaccaccat actccggctc aactaacttt taacgagagt
    28321 ttctaaactc cttcgtcctc cagtctacaa aagccttcca ttcgtactat cctatatttt
    28381 atgaggggac acatttttcc tatcagacca tttattttaa agatagaagt aaatcataat
    28441 tgcttccatc tgttctttta tagtatattg aagttagact agagcactgt atcttctaaa
    28501 acattgatag aaagcgattt gaatttccca atcaatttgt tcgtatttat agcatttcga
    28561 aactggaata ggacaccatg actgctaaaa gatttctata aattcatttg attttcctaa
    28621 tcaatttgtt catatcttat ttcattccgc tataatttca ccttacccta tctttttcgt
    28681 agcacccttc aaacagccta tcccctaccg tttgacgatt cctcacttcg ctccacttcc
    28741 attacagaag tttcttcact actatgggct cggctgactt ctcatgattc cttgttacta
    28801 ctatttgaac gctcacgaga tagatcttac aaaaaatgct ttgatccaca atggaatcaa
    28861 agcattttaa agagttcctc atacataagc gcagaagtcg cagttcctct gtacttggct
    28921 tcttctcttt tgataaagcg agccaagttg agcaactcag gtgctggatg tttgggattt
    28981 aggagcaatt cacgattgac caggcctgag agacgaactg cctgcaattg ttcatttgta
    29041 gtaggcagtt ttttagcagt ctctaggaga gcagcaacta aatcttcact caaatcatgt
    29101 cgagcatgat tgtaaagatc ttttataagg ctttctaggt ttggttctgc catccctacc
    29161 acctccctta tggtttaata atgtttaatc aaatcaaccg ttgaacgatc caatttcttc
    29221 accaaggctt gtaagaaagc ttgcgcttct aggaagtcat ccattgcata gagggtttgg
    29281 tgagaatgga tataacgagc gcagacaccg atagttgttg atgggacacc accatttttc
    29341 agatgagctg cacctgcatc tgttccgcct ttaccacagt agtattggta cttgatacca
    29401 gcttcttcag ccgttgtcaa aagaaaatcc ttcatccctg ggagaagcaa gtgacctgga
    29461 tcatagaaac gaatcaaggt tccatctcca attttgcctt gaccaccgta gacatcacct
    29521 gctggtgagc aatcaactgc gaggaagact tctgggtcaa acttggttgt agaggtatga
    29581 gcgccacgca gaccaacttc ttcttggacg ttagaaccca gatagagttc attgccgagt
    29641 ttttgacctg ataaagcttc agctagctcg cttaccatga ggacaccgta gcggttatcc
    29701 caagcttttg agatgatatt tttttcattg gctgtcaaaa ttgcagaact atctggtacg
    29761 atggtatcac caggacggat gccaaaactt tctgcctcag ccttgtccgc aaaaccacca
    29821 tcaaaaacga tatcggcaat ggctggcatg gttggtcccc cctttccacg agtcaaatgc
    29881 ggaggaacag aacctgaaat cacaggaatt tcatgaccat cacgagtcaa gagtttgaaa
    29941 cgttggctgc taaccaccat ggggttccag ccaccgattt ctacgacacg gaaggtacca
    30001 tctggcttga tttcgctgac cataaaacca acttcgtcca tatgagaagc gaccaagacg
    30061 cgcggtgcat ccacagcttc tgaatgtttg ataccaaaaa taccacccaa gccatctgtc
    30121 accacttcat ccacatacgg tgtcaacttt tcacgaagat aagcacggac aggcgcttca
    30181 tgacctgaga ctgcagcaag ttctgttact tctttaattt ttgaaaataa tgttgtcatt
    30241 tcagttcctt ctttctttca tccattttac cactttttat aggagaagga tagtgggaag
    30301 gtggatttct aagttagtat cttagtcctg ctctatctta gaaaaggata gtattctctt
    30361 gcatgtagtg caaaatctag taaacattcc aaaattaact cgaatattta tttccaaaca
    30421 aaaaaacaat acaccatcaa agttgtttag atttttcatg aaatttacag aaaatagttg
    30481 acttcccttt cttctttctt taaata
//
LOCUS       DAVLZG010000021        29684 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLZG010000021 DAVLZG010000000
VERSION     DAVLZG010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.021"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            364..1527
                     /locus_tag="VYO72_000912"
     CDS             364..1527
                     /locus_tag="VYO72_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1707312.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1524..2201
                     /locus_tag="VYO72_000913"
     CDS             1524..2201
                     /locus_tag="VYO72_000913"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1707313.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2191..3045
                     /locus_tag="VYO72_000914"
     CDS             2191..3045
                     /locus_tag="VYO72_000914"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1707314.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3064..4131
                     /locus_tag="VYO72_000915"
     CDS             3064..4131
                     /locus_tag="VYO72_000915"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1707315.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            4141..5307
                     /gene="aroC"
                     /locus_tag="VYO72_000916"
     CDS             4141..5307
                     /gene="aroC"
                     /locus_tag="VYO72_000916"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1707316.1"
                     /translation="MRYLTAGESHGPRLTAIIDGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5317..6420
                     /locus_tag="VYO72_000917"
     CDS             5317..6420
                     /locus_tag="VYO72_000917"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1707317.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6431..6769
                     /locus_tag="VYO72_000918"
     CDS             6431..6769
                     /locus_tag="VYO72_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1707318.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6861..8144
                     /gene="aroA"
                     /locus_tag="VYO72_000919"
     CDS             6861..8144
                     /gene="aroA"
                     /locus_tag="VYO72_000919"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1707319.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLSPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8137..8613
                     /locus_tag="VYO72_000920"
     CDS             8137..8613
                     /locus_tag="VYO72_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1707320.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8610..9458
                     /gene="pheA"
                     /locus_tag="VYO72_000921"
     CDS             8610..9458
                     /gene="pheA"
                     /locus_tag="VYO72_000921"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1707321.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9455..10729
                     /gene="psr"
                     /locus_tag="VYO72_000922"
     CDS             9455..10729
                     /gene="psr"
                     /locus_tag="VYO72_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1707322.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     RNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11008..11853
                     /locus_tag="VYO72_000923"
     CDS             11008..11853
                     /locus_tag="VYO72_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1707323.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11843..12946
                     /locus_tag="VYO72_000924"
     CDS             11843..12946
                     /locus_tag="VYO72_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1707324.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12948..13934
                     /locus_tag="VYO72_000925"
     CDS             12948..13934
                     /locus_tag="VYO72_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1707325.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13950..15383
                     /locus_tag="VYO72_000926"
     CDS             13950..15383
                     /locus_tag="VYO72_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1707326.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            15412..16446
                     /locus_tag="VYO72_000927"
     CDS             15412..16446
                     /locus_tag="VYO72_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1707327.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16588..17325
                     /gene="mecA"
                     /locus_tag="VYO72_000928"
     CDS             16588..17325
                     /gene="mecA"
                     /locus_tag="VYO72_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1707328.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17476..18762
                     /locus_tag="VYO72_000929"
     CDS             17476..18762
                     /locus_tag="VYO72_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1707329.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVVHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18764..19633
                     /locus_tag="VYO72_000930"
     CDS             18764..19633
                     /locus_tag="VYO72_000930"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1707330.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19883..20821
                     /gene="msrB"
                     /locus_tag="VYO72_000931"
     CDS             19883..20821
                     /gene="msrB"
                     /locus_tag="VYO72_000931"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1707331.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20879..22603
                     /locus_tag="VYO72_000932"
     CDS             20879..22603
                     /locus_tag="VYO72_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707332.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            22605..24356
                     /locus_tag="VYO72_000933"
     CDS             22605..24356
                     /locus_tag="VYO72_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707333.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            24703..25962
                     /locus_tag="VYO72_000934"
     CDS             24703..25962
                     /locus_tag="VYO72_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1707334.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26038..26173
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26212..26712
                     /locus_tag="VYO72_000935"
     CDS             26212..26712
                     /locus_tag="VYO72_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1707335.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26788..27156
                     /gene="rplL"
                     /locus_tag="VYO72_000936"
     CDS             26788..27156
                     /gene="rplL"
                     /locus_tag="VYO72_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1707336.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27343..27513
                     /locus_tag="VYO72_000937"
     CDS             27343..27513
                     /locus_tag="VYO72_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707337.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27513..27761
                     /locus_tag="VYO72_000938"
                     /pseudo
     CDS             27513..27761
                     /locus_tag="VYO72_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27775..28115
                     /locus_tag="VYO72_000939"
                     /pseudo
     CDS             27775..28115
                     /locus_tag="VYO72_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28108..28488
                     /locus_tag="VYO72_000940"
     CDS             28108..28488
                     /locus_tag="VYO72_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1707338.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            28501..28644
                     /locus_tag="VYO72_000941"
     CDS             28501..28644
                     /locus_tag="VYO72_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707339.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            28737..29324
                     /locus_tag="VYO72_000942"
     CDS             28737..29324
                     /locus_tag="VYO72_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707340.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            29526..29663
                     /locus_tag="VYO72_000943"
     CDS             29526..29663
                     /locus_tag="VYO72_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1707341.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         8833 a         5442 c         6645 g         8764 t
ORIGIN      
        1 agtttgtaac aaaaggcttt tctataaaat caaattttcc agatacctat tgaagcagat
       61 ttatttcttc atctttcttc tactaccttt gtcactaaat ttgacagaca catattgctg
      121 attcaacctc tctacctata atctcacagt taacctgagg ctagtttcat agtttgctat
      181 ttgattttcg ttgataaaaa gaaatgctcc tccaagatgg aagagcattt tttattgtga
      241 ttcttacaca tttacttcct agttttgcag gaagtctagt ataccatttt ttaaaagaag
      301 agtaaaaaag caagggtagt ttcttttttg agaattgtct aaaagtttga tataatggta
      361 gttatgaata gaataagagt cagcaaaagg gttgaaaaga agcttgctaa ggggctagtt
      421 ttactagaag ccagtgatct tgagaatgtc aatcttaagg atcaggaagt agaggtgcag
      481 ggtcaggaag gaaactttct tgggactgcc tacctttctc agcaaaacaa gggcttgggc
      541 tggtttgtca gcaaagacaa ggtggccttc aatcaagctt tctttgaaac gttgtttaga
      601 aaagccaaag aaaagagaaa cgcctactat caagatgatt tgacaactgc ctttcgtctc
      661 tttaatcaag agggagatgg ctttgggggt ctgacagtgg acctttatgg cgactacgcc
      721 gtcttttctt ggtataactc ttatgtttat cagattcgtc agactatatc agaagccttt
      781 agacaggttt tccctgaggt tttaggagct tatgagaaaa tccgctttaa gggtttggac
      841 tatgaatctg cccatgttta tggtcaagaa gcacctgact ttttcactgt tttagaaaat
      901 ggtgtcctgt atcaagtctt tatgaatgat ggcttgatga caggaatttt cctagaccag
      961 catgaggttc gcggtagttt agttgacggc ttggctatgg gtaaatcctt actcaatatg
     1021 ttttcctaca cagcggcttt ttcagtagct gcggccatgg gaggagctag ccagacaact
     1081 tctgttgatc tagccaaacg ttcacgagaa ttgtctcaag cgcattttca ggcaaatggg
     1141 ctcagcacag acgagcatcg ttttatagtc atggatgtct ttgagtattt caaatatgcc
     1201 aaacgcaaag acttgaccta cgatgtgatt gtcctagatc cgcctagctt tgctcggaat
     1261 aaaaaacaaa ctttctctgt ggccaaggat tatcacaagt tgatttccca gagtcttgag
     1321 attttaaatc cgggagggat tatcattgcc agtaccaatg ctgccaatgt ttcccgtcag
     1381 aaatttacag aacaaattga taaaggtttt gcaggaagaa gttaccagat tttaaacaaa
     1441 tatggtcttc cagcagattt tgcctataat aaaaaagatg aaagtagtaa ttacctcaag
     1501 gtgattagta tgaaggttag taaatgaaat taatcgtttc agtaatgcca agaagtttag
     1561 aggaggctca ggctctggat gccacgaggt acttggatgc cgacatcatt gaatggcgtg
     1621 ccgactatct gcctaaagaa gcgattttgc aggtagctcc agccattttt gaaaaattcg
     1681 caggccgtga gttggttttc acgctacgaa ctcgctccga aggtggagaa atcgaccttt
     1741 ctccagaaga gtatatccat ctaatcaagg aagttgcgca actctatcaa ccagactata
     1801 ttgattttga gtactatagc tacaaggatg tttttgagga aatgctggac ttcccaaatc
     1861 ttgttttgag ttaccataat ttccaagaaa cacctgagaa catgatggaa atcttgtcag
     1921 agttgacgat cctaaatcca aaacttgtta aggttgcggt gatggctcac acggagcagg
     1981 atgtcttaga cttgatgaac tatacacgag gctttaaaac cctcaatcct gaacaggaat
     2041 atgtgaccat ttctatgggt aaggtgggca aggtctctcg tatcactgcg gatgtgactg
     2101 gttcgagttg gtcttttgcc agtctggatg aggttagtgc ccctgggcag atttctctag
     2161 ctagcatgaa aaaaatcagg gagattttgg atgaagcttg atggctatac acgtttagct
     2221 gcagttgttg ccaatcctat taagcattct atttctccct tcatccacaa tagagccttt
     2281 gaggcgacag ctaccaacgg tgcttatgtg gcttgggaga ttgaagcgag tgacttggca
     2341 gaaacagtgg ccaatattcg tcgctaccag atgtttggca tcaatctgtc catgccctat
     2401 aaggagcagg tgattcctta tttggatgag ctaagcgatg aagcgcgctt gattggtgcg
     2461 gttaatacgg ttgtcaatga gaatggcaat ttaattggat ataatacaga tggcaaggga
     2521 ttttttaagt gcttgccttc ttttacaatt tcaggtaaaa agatgaccct gctgggtgca
     2581 ggtggtgcgg ctaaatcaat cttggcacag gctattttgg atggcgtcag tcagatttcg
     2641 gtctttgttc gttccgtttc tatggaaaaa acaagacctt acctagacaa gttacaggag
     2701 cagacaggct ttaaagtgga tttgtgtgct ttagaatatg tttctgaact gcaagcaagg
     2761 attgccgagt cggatttgct agttaatgcc accagtgtgg gcatggatgg ccaatcctct
     2821 cctgttcctg aaaacatagt cttaccagaa actcttttag ttgcagatat catataccaa
     2881 ccctttgaaa caccgttttt gaaatgggct agaagtcagg gcaatccagc agtcaatggt
     2941 ctgggaatgt tgctctatca agctgcagaa gcttttcaac tgtggacagg caaggaaatg
     3001 ccgacagaag agatttggca gtctttaaca gaaaaatacc aataaagaaa gggagactct
     3061 cctatgaaaa tcagaatcga tattcctcat catccttatg atattcagat tgaaaaaggt
     3121 tgtatggccc aggctggtca gtggttgcga gaactctggc aaccgcaaaa ggtagtcatt
     3181 gtgacagata accatgtagc ctctctctat gcagagaagg tcaagctcag cctagaagat
     3241 gctggttttc aggtagctgt ttttgatttc ttagaaggtg aagaaagaaa gaatttaact
     3301 actgttcaga aagtctatga atttctagtc aagcaaggtc tgactcgtag cgatggaatc
     3361 gttgctcttg gtggtggcgt tgttggggac ctggctggct ttgtagcctc tacctatatg
     3421 cggggtattc actttgttca gattccgact agtttgacag ctcaggttga ttcttctatc
     3481 ggtggaaaga caggcgttaa cacaccattt gctaaaaata tggtggggac ctttgcccaa
     3541 ccagatgggg ttctgattga tccacttgtt cttgaaaccc tcggaaaaag agagttgatt
     3601 gaagggatgg gtgaagttat caagtatggc ttgattgagg atccagaact gtgggctctc
     3661 ttgacgggac tgaatggttc tgttgagagt attttggaac atgcagagac cttgattgaa
     3721 cattcttgtc aggtgaagcg caagatggtg gttgaagatg agttggacaa tggtattcgt
     3781 ctttacctca attttggcca cactattggc catgccatcg aagcgactgc cggttatggc
     3841 aaggtcatgc atggagaggc tgttgccatg ggaatggtac agatttccaa gattgctgag
     3901 gaaaaaggcc tcatgccagc tggcattacc caatctatca cagagatgtg tcagaaattc
     3961 ggcttgcctg ttgactatga aaattgggaa gttgacaagc tttatcaggc tcttactcat
     4021 gacaagaaag cgcgtggcaa caccttgaaa ttggtcttgg tgccagagct tggttcagcg
     4081 atcattcacc cagtttctct ggaagagatg aaagactact tggtaaaata aggagagtgt
     4141 atgagatatt taactgcagg agaatcacac ggcccccgtc taacagctat tattgatgga
     4201 attccagctg gacttccatt gacagctgag gatatcaatg aggaccttag acgccgtcag
     4261 ggtggctacg gtcgtggtgg tcgtatgaag attgagaatg accaggttgt ctttacttcg
     4321 ggcgttcgcc acgggaagac gacaggggcg cctattacta tggatgtcat caataaggac
     4381 caccagaaat ggctggacat catgtctgcg gaggacattg aagaccgtct taaaagcaag
     4441 cggaaaatta ctcatcctcg cccaggtcat gccgatttgg ttggggggat taagtaccgt
     4501 tttgatgatt tgcgaaattc tttggagcgt tcatcagctc gtgaaaccac catgcgggtg
     4561 gcagttggtg cagtagccaa acgcctcttg gctgagttgg atatggagat tgccaaccat
     4621 gtcgtggtct ttggtggcaa ggaaatcgat gttcctgaaa atctgacagt cgctgaaatt
     4681 aagcaaagag ctgcccagtc tgaagtttct attgtcaacc aagaacgaga acaggaaatc
     4741 aaggactata ttgaccaaat caaacgtgat ggtgatacca tcggtggggt tgtggagaca
     4801 gtcgtcggag gcgttccagt tggtcttggt tcctatgtcc aatgggatag aaaattggat
     4861 gcaagattgg ctcaagctgt tgtctctatc aatgccttta aaggggtgga atttggtctt
     4921 ggctttgagg ctggttatcg taaaggcagc caagttatgg atgaaattct ctggtctaaa
     4981 gaagacggtt atactcgccg taccaataat ctaggtggtt ttgaaggtgg tatgactaat
     5041 gggcaaccca tcgttgttcg tggggtcatg aaacccattc ctactcttta taaacctctt
     5101 atgagtgtgg atatcgaaac ccacgaacct tacaaggcaa ccgtggagag aagtgatccg
     5161 actgctcttc cagctgcagg aatggtcatg gaagcagttg tagcaacggt tctggcgcaa
     5221 gaaatcctcg aaaaattctc atcagataat cttgaggaac taaaagaagc ggtagccaaa
     5281 caccgagact atacaaagaa ctattaagga gttcctatgg caaaaacaat ctatatcgca
     5341 ggtcttgggt tgattggagc ctctatggca cttggtatca aacgcgatca tccagattat
     5401 gaaattttag gttataatcg tagtcaagct tcgagagata tcgccttgaa agaaggcatg
     5461 attgaccgtg caacggatga ttttgctagt tttgctcctt tggcagatgt cattatcctc
     5521 agcttgccaa tcaaacaaac tattgctttc attaaggagt tggccaattt ggatttgcga
     5581 gaaggcgtta ttatttcaga tgctggttcg accaagtcaa ccattgtgga tgcggcggag
     5641 cagtatttgg ctggcaagtc tgttcgcttt gtcggggccc atcccatggc tggtagtcac
     5701 aagacagggg ctgcttcggc agatgtcaat ctttttgaaa atgcctatta tatctttaca
     5761 ccttcaagcc tgacaagtca ggacacgctt aaggaaatga aggatctgct ttcaggtctt
     5821 catgctcgtt ttatcgagat tgatgccaag gagcatgatc gtgtcacttc tcagattagc
     5881 cattttcctc atattttggc ttctagtctc atggagcaga ctgcggtcta tgctcaagag
     5941 catgagatgg caaggcgctt tgcggcaggt ggttttcgag atatgacccg aattgcggaa
     6001 agcgagccag gaatgtggac ctccattctc ttgtccaata gcgagatcat tctggataga
     6061 attgaggatt tcaaggaacg tttggaagcg attggtcagg ccattagtaa gggagatgaa
     6121 gagcaaattt ggaacttttt taaccaagcg cgtgaacaac gccagaccat ggaaatccat
     6181 aagcgtggtg gtgtggatag ctcttacgac ctctatgttg acgttcctga tgaagaagat
     6241 gtcatcctgc ggattttgga actgctacgt ggaacttcct tggttaatat ccacatcaac
     6301 gaggaaaatc gtgaggatat tcacggaatc ctacaaattt catttaaaaa tgctcaagac
     6361 ttggaaagag ctgagcatct cataacagaa aatactgact atacagtcgt catcaaataa
     6421 ggagaagaac atgtcaaata tttacgatag tgcaaacgaa ctcagtcgcg gtctacgcgg
     6481 attaccagaa tacaaggctg ttaaagcagc taaagatgcg attgcagcag atgctgaggc
     6541 aagcaaaatc tttacagatt atcttgcctt tcaagaggaa attcaaaaac tagcacagac
     6601 aggtcaaatg ccagatgcgt ccttccaagc taagatggaa ggctttggta aacagattca
     6661 aggaaatagc ctcttgtcag aattctttac caagcaacaa caattggcca tttacctttc
     6721 tgacattgaa aaaattgttt ttgaaccagt ttcagaattg ctgaaataag aaaagaacta
     6781 tcctaaagtc aggaattttt aaggaatttc tggcttttta tgataaaata ggtaaaagta
     6841 ttgcaagtat gaggtccagt atgaaactaa aaacaaacat tcgccattta catggtagta
     6901 tccgcgtccc aggtgacaag tctatcagcc accgttccat tatctttgga agtttggctg
     6961 agggtgagac caaggtttat gatattctgc gaggcgaaga cgttctttcg accatgcagg
     7021 tttttcgtga ccttggtgtt gaaattgagg ataaagatgg ggttattacc attcaaggtg
     7081 taggcatggc tggcttaaaa gcgccgcaaa atgcccttaa tatgggaaat tctggcacct
     7141 cgattcgcct gatttcaggt gtccttgctg gtgcagattt cgaagtagag atgtttggag
     7201 atgatagtct ttccaaacgt cctatggacc gtgtgaccct tccactgaaa aaaatgggcg
     7261 tcagcatttc agggcaaact gaacgagact tgcctcccct tcgcttaaaa gggacgaaaa
     7321 acctaagccc tattcattat gagttgccaa ttgcctctgc ccaagtcaag tcagccttga
     7381 tgtttgcagc cttacaagct aagggggagt cagttattat cgaaaaagaa tacacccgta
     7441 atcatactga agatatgttg caacaatttg gtggtcattt aagtgtggat ggtaagaaaa
     7501 tcacagtcca agggccacaa aaattgacag gacagaaggt ggtcgtacca ggagatattt
     7561 ccagtgcagc cttttggtta gtcgcaggtt tgattgctcc aaattctcgt ctagtgctgc
     7621 agaatgtggg gatcaacgaa actcgcaccg gtattattga tgtcattcgt gccatgggtg
     7681 gaaaattgga aataactgaa atcgatccag tcgctaaatc tgcaaccttg attgttgagt
     7741 cttctgactt gaaaggaaca gagatttgtg gcgctttgat tccacgtttg attgatgaat
     7801 tgcctattat tgccctactt gcgacccaag cccaaggtgt aacagttatt aaagatgctg
     7861 aggagctcaa ggtcaaggaa acagaccgta ttcaggttgt ggcagacgcc ttaaatagta
     7921 tgggagcaga tattactcct acggcagatg ggatgattat caaaggaaaa tcagctcttc
     7981 acggtgctag agtcaatacg tttggtgacc accgtatcgg catgatgaca gctatcgcag
     8041 ccctattggt tgcagatgga gaggtggagc ttgaccgtgc agaagccatc aataccagct
     8101 atcctagttt ctttgatgat ttggagagct tgattcatgg ctaaggtgtt attagggttt
     8161 atgggggctg gaaaatcaac tattgcaaga ggcttggacc ctaattacct tgatatggat
     8221 gctctgattg agaagcgcct aggtatgtcc attgcgaatt ttttcgctga aaagggagaa
     8281 tcagcctttc gtcaggtaga atcagaagtc ctagctgatt tactacaaac agaccaagtc
     8341 gtgtcaactg gaggaggagt ggttatttct cagagaaatc gtgacttact caagactaat
     8401 acagataaca tctacctgaa agcagatttt gaaaccctct acctacgtat cgtagctgat
     8461 aaggacaatc agcgaccgct ttttctaaat aatagcaagg aagaactagt agctattttt
     8521 caagaaagac aggcttggta tgaggaagtg gctagtcggg ttttggatgt gaccaagcta
     8581 agcccagagg aaattataga ggaactaaga tgaaaattgc ttatctaggt cccaaaggat
     8641 cattttcaca ccacgttgtg cagacagctt ttcctcatga ggaattgcag gcttttgcca
     8701 acattacaga tgttatcaag gcttatgagc aaggattagt ggactattct gtggtgccag
     8761 ttgaaaattc tattgagggt agtgttcatg aaaccttgga ctatcttttt catcaggctc
     8821 acatccaagc agtagcagaa atcgttcagc ctattcatca gcagttgatg gtggttccag
     8881 gccatactaa gattgaaaag attttttcac atccacaggc cttggctcaa ggaaagaaat
     8941 tcatcgatga acaatatcca gaggctcaaa tcgaggtaac agctagtaca gcttatgcgg
     9001 cccgttttat ttccgaacat ccagaccagc cctttgcagc agttgcacct agaagttctg
     9061 ctgaagaata tggattggaa ctgattgccg aggatattca ggaaatggaa gccaatttca
     9121 cacgtttctg ggttctagga gctgaaaagc ctagtattcc cttgcaagca caaactgaaa
     9181 agatgagttt ggccttgaca ttacctgaca accttccagg tgcactttat aaggccctgt
     9241 cgacctttgc ttggcgagga attgacttga caaaaattga aagtcgtcca ctcaagacag
     9301 cactgggtga atactttttc attatcgatg tggattatac cgataaggac ttggtccact
     9361 ttgcccaaaa agaattagaa gcgattggaa tccagtataa aattctgggt gcctatccta
     9421 tttatccaat atcagaccat ggaaaggaga gaagatgagt aaagaaaatc ccttaagtca
     9481 tcatgagcag ttgcgttatg attatttgct aaaaaatatt cactacctca atgagagaga
     9541 aaaaaatgag tttgcctatt tgcaagaaaa gctaactctt gctaggagaa atagtagctc
     9601 tagcttggaa caagaaagag aagagcaggt tgacttacca agttatgcga accggagtcg
     9661 ctcacaatcc aaatcacaag cactctcttc ccctccaaaa aagaaaagac ggaagctccg
     9721 tcttaaacga atttttatgg tgattttttc acttttggtc tgtgtggctt tggccatggt
     9781 attcatgttt ttgcgtggtt accaagatgc tagcgcaaag aaaactgctg atgcccgggc
     9841 agctcaagta gaagtcttta atggtcagga cactagagat ggagttaata ttttaatcat
     9901 gggtactgat ggtcgaatcg gccagaacag tgttgagaca cgaactgact ctattatggt
     9961 attaaatgtc gggggctcag ataagaaaat gaagctagtc agtttcatgc gtgataattt
    10021 ggtctatata gatggttata gtcaagtgat taacggtaga aaacagacag ataacaagtt
    10081 aaacgtagcc tacgagttag gagaacaaga ggggcaaaaa ggggcagaaa tggttcgcca
    10141 agtcttgaaa gataattttg acttggacat taagtactac gccttggttg atttccaggc
    10201 ctttgccaca gcgattgaca cacttttccc tgatggggtg acgattgatg ctcaattttc
    10261 aacattgaat gggcgtcccc taacagaagc tacagtcgga gatgatttat acgctaccga
    10321 gactgagtct ccaacccaaa ccattaaagt cggaaaacag cagatgaatg gctcgaccct
    10381 gctcaattat gctcgtttcc gtgatgatga tgaggcggat tacggccgta caaaaagaca
    10441 gcaacaagtt ttaacagcaa ttttagagca aattaaagat cccactaaac ttttcactgg
    10501 ttctgaagct cttggaaagg tttttgctat gacctcaacc aacgtaccct atactttcct
    10561 cctaacaaac ggtttatctg ttttggatgg agcaaaaaat ggtattgaaa aattgacgat
    10621 tccagaactg ggtgactggg tagatgccta tgatgtttat ggaggcttgg gcttgctggt
    10681 tgatcaaaac aaatatcaaa ccaagctcgc tcaaatgggc ttgagataag ataatactca
    10741 atgaaaatca aagtgcaaac taggaagcta gccgcaggct gctaaaaaca cagttttgag
    10801 gttatagata agactgacga agtcagttac ctatacctac ggcaaggtga agctgacgtg
    10861 ctttgaagag attttcgaag agtataagac agaaaaatca aagtttgata gctatttgga
    10921 tagcagtcag gctttgattt tttacagtct gcaatagatt ttcacccctt gtttgtggta
    10981 taatgaaacg atacgataga aagaataatg aacaatatga ctgatttaaa agcaattcag
    11041 gctcgtagtc tggagatggc tgaatatttt gtggcctttt gtaaagaaca tgatttgctc
    11101 tgttatctct gtggcggagg cgctattggt acccttcgaa acaagggatt tattccttgg
    11161 gacgacgacc tagacttttt tatgcctcgt aaagattatg agaaattagc agaattatgg
    11221 cctcgttatg cagatgaacg ttatttcttg tcaaagagtt acaaggattt tgttgatcgt
    11281 aatcttttta ttaccattcg tgacaaggaa accacctgta tcaagcctta tcagcaggat
    11341 ttggatttgc cacatggtct ggccttggat gttttgcctt tggattatta tccgaaagat
    11401 ccagctgagc ggaaaaaaca ggttcgttgg gccttgattt attcactctt ttgtgcgcaa
    11461 actattccag aaaagcatgg tgctctcatg aaatggggaa gtcgcatttt actgggtttg
    11521 actccaaaat ctctccgtta tcgcatctgg aaaaaagctg agaaagaaat gactaagtat
    11581 gatttggctg attgtgatgg cattacagaa ttatgctcag gtcctggcta catgagaaac
    11641 aagtacccaa tcacatcttt tgaagacaat cttttcttgc catttgaggg aacagagatg
    11701 cctattccaa tcggctatga tgtctatctc agaactgctt ttggggatta tatgacgcct
    11761 ccaccagcag acaagcaggt accgcatcat gatgctgtca tcgctgatat ggataagtct
    11821 tatacagaat acaagggaga atatggtggc taagaaaaaa atcttatttt ttatgtggtc
    11881 tttttctctt ggaggtggtg cagagaagat tctatcaacc attgtttcaa atctggatcc
    11941 agaaaagtat gatattgata ttcttgaaat ggagcacttt gacaagggat atgaatctgt
    12001 tccaaagcat gtacgcattt taaaatccct tcaagattat cgccaaacca gatggttacg
    12061 agcttttttg tggagaatga gaatttattt tccaagactg gctcgtcgtt tgcttgtaaa
    12121 agatgattat gatgttgaag tttcttttac cattatgaat ccaccactgt tgttctctaa
    12181 aagaagagaa gtcaagaaga tatcttggat tcatggaagt attgaagaac ttcttaagga
    12241 tagctctaaa agagaatcac atagaagcca gttggatgct gcgaatacaa ttgtagggat
    12301 ttcaaaaaag accagcaatt ctatcaagga agtttatcca gattatgctt ctaaattaca
    12361 gacaatctac aatggatatg attttcagac tattctagaa aaatctcaag agaagatcga
    12421 tatcgagatt gctcctcaaa gtatctgtac tatcggacgg attgaggaaa ataagggttc
    12481 tgaccgtgta gtggaagtga tacgattatt acaccaagag ggaaaaaact atcatctcta
    12541 ttttatcggg gctggtgata tggaagagga actgaaaaaa cgagtcaaag agtatgggat
    12601 tgaggactat gtacatttcc ttggttatca aaaaaatcct tatcagtatt tatctcagac
    12661 gaaagttctc ttgtctatgt ctaaacaaga aggttttcct ggagtgtatg tggaggcctt
    12721 gagtctggga ctccctttta tctctacgga cgttggaggg gctgaggaat tatcccaaga
    12781 aggacgattt ggacaaatca ttgagagcaa tcaagaggca gctcaggcga ttactaatta
    12841 catgacttct gcctcaaact ttgatgtcga tgaggctagc caattcattc aacaatttac
    12901 aattacaaaa caaatcgaac aagtagaaaa actattagag gagtagcatg gaaactgcat
    12961 taattagtgt gattgtgcca gtctataatg tggcgcagta cctagaaaaa tcgatagctt
    13021 ccattcagaa gcagatctat caaaatctgg aaattattct tgttgatgat ggtgcaacag
    13081 atgaaagtgg tcgcttgtgt gactcaatcg ctgaacaaga tgacagggtg tcagtgcttc
    13141 ataaaaagaa cgaaggattg tcgcaagcac gaaatgatgg gatgaagcag gctcacgggg
    13201 attatctgat ttttattgac tcagatgatt atatccatcc agaaatgatt cagagcttat
    13261 atgagcaatt agttcaagaa gatgcggatg tttcaagctg tggtgtcatg aatgtctatg
    13321 ctaatgatga aagcccacag tcagccaatc aggatgacta ttttgtctgt gattctcaaa
    13381 catttctaaa ggaatacctc ataggtgaaa aaatacctgg gacgatttgc aataagctaa
    13441 tcaagagaca gattgcaact gccctatcct ttcctaaggg gttgatttac gaagatgcct
    13501 attaccattt tgatttaatc aagttggcca agaagtatgt ggttaatact aaaccctatt
    13561 attactattt ccatagaggg gatagtatta cgaccaaacc ctatgcagag aaggatttag
    13621 cctatattga tatctaccaa aagttttata atgaagttgt gaaaaactat cctgacttga
    13681 aagaggtcgc ttttttcaga ttggcctatg cccacttctt tattctggat aagatgttgc
    13741 tagatgatca gtataaacag tttgaagcct attctcagat tcatcgtttt ttaaaaggcc
    13801 atgcctttgc tatttctagg aatccaattt tccgtaaggg gagaagaatt agtgctttgg
    13861 ccctattcat aaatatttcc ttatatcgat tcttattact gaaaaatatt gaaaaatcta
    13921 aaaaattaca ttagaacggg ggtgaccaag tgattgatgg gaaacgatta ttatttagtt
    13981 tgaccatagt cagttatgcc ttgacgctag taagtggaat tgtgtatctg tttaataata
    14041 ataatgttag cttactttct actttattgt tcttgttggt tagtagctta attgcttgtt
    14101 ggaatgatat caagtattac ttaatccatt ttattttcta tttaaccatt tttgtatttc
    14161 tggtatcaag accgaccatt gattatttta gggatggtgc tttggatacc tatcatccaa
    14221 tagcctatcg ttttgccttt atagttgtca tggtttcgat tctgggcttg accacaggag
    14281 gcattctggc tcgttacttc atagctagga agaaaataaa agtagcaaat ataggaaatt
    14341 ctctaaaaga ggtttatatc aagcggttac gctttgtatc actaggagtt tttcttctaa
    14401 cctatccttt ctatttcatt cggttatttg aacggctctt gtatcgtttg cagacttcct
    14461 actatgccta ctatgcaaat tttgaaagta aactgcctta ttttacctac attttgtcta
    14521 cctttacggt ctatgcaatg tgtatgtatc tggcaaccaa gccaaagaaa ttgcaggcca
    14581 cagcagtgct tgtctccttt attgcagcta atactattca tttggcaatt gggacacgaa
    14641 atccctttat tttaagtatt ttatttgctt ttgtttatta ctttatgcgg gagcaaactg
    14701 aaaaaggaaa atggattggg tttaaagaaa agttagcgat ttttgtaggt tctcctattc
    14761 tcatgttagc gatgggagta ctcaattatg tacgggataa tgtccaagtt tcccatacag
    14821 gtttctggga tatcttactt gactttatct ataaacaagg gactagtttt ggtgttctgg
    14881 ctcgaggttt tctatttaac agtagcctcc cttaccgaga tttccgtaat tttacttttg
    14941 gtcctgttct tgattatttt gcaaggggga gtttgggagc cattttcgga ggaaaagcct
    15001 ttgaacatac aaccaatagt gtggaactag ctattgatag taatagttat gcccacaatc
    15061 tatcctatct tgtcttgaac aaggaatacc tgaaagggca tggtatcgga agtagttata
    15121 tcatggagtt gtataccgac tatggtatga ttggagtctt tctgcttagt ttcttactcg
    15181 gcgtattatt tatagccatg ctgcaagtag cctatcgctc aaggacaatc ctatttgctt
    15241 tatccctact catcttgaat aatctattct ttatgccaag aagcagcttt tcagaaagtt
    15301 tcttcaattt atttacaatg caattctggg gaattgttct tgtgattata tttatagcaa
    15361 aaatgcttac aaaggaaaac tagtatctac taaacaaagg agaaaaaaat catgtttgaa
    15421 cattattcag tagctgattt gtttgcaaat ctttataaaa agcgaaaagc aaatatttta
    15481 gctctcatcg ctttatttgc tctcattgct gtaccattta caattaaagc agttaggaat
    15541 aaaaacactg tcaaagatac aacaagttat tcaacttatc ttatctataa aatcactcct
    15601 ccaaaagagt cggccaaaac gattttgaat catcaaattg gtggttatag tgatttttat
    15661 gggaaattga ttgatggtaa tttgaatgga gcttatcttt tcaatgatgt agaacccagt
    15721 gagttgaaaa aaattgccag tgaattagac acgacagaaa caaccttgaa aaattcaacg
    15781 aatgactatt ggtggaaaaa attgaccgtc tactatatga ttgacgatgc aggggttggt
    15841 gtgaaaattt tgacatcaag taaagatgcc aatgacttgt tagagaaaaa aattgatggg
    15901 ttgattgaga aatttaaaca tgcctatgca aatgtgaaaa ttgaaaaact ggaaaccatc
    15961 aactctaaag aattgaacgc aaatggtgaa acagcgcttg gcttaaatgt gaaaaatctg
    16021 attcttcgtt tagttgttat tggagtggtt tgtgtgattt tggttgtgat gggaaatgtg
    16081 ttagtttatc tctttaatcc aacaatcaat agagtaggtg atttttctca gtatcaaatt
    16141 gattttgtaa cagagattac aacaattgct aacctagcag atgttttgtc atacaaaaat
    16201 actggacagg aattgaccat cgttagctca aataaagcta tcctagataa attgaaacag
    16261 agtcaagaag ctttaaaagg aatgcatttt gtagatttac aggatgtatc atctcttttg
    16321 gaaagagata cagtccttct tgttgaagag tacggagtga ctcgttataa gaaatttgag
    16381 caaagtcttc aaattctcag aaacttaaat cgttctatcc tcggtgtagc aacctttaaa
    16441 ttataagtat tctgatgtat aaggtcttca aagtcggcta agagccgatt ttgaaggctt
    16501 tttctatctg tctgcagaaa ttttcttttg ataaaatcgt aaaaatctag tataatagat
    16561 agaactgaaa gtatgaggtt actagcaatg aaaatgaaac aaattagtga tacaacttta
    16621 aaaatcacga tatctttaga ggatttgatg gatcgtggaa tggagattgc tgactttctc
    16681 gttcctcaag aaaaaacaga agagttcttt tatgctatct tggatgagct agagatgcct
    16741 gatagctttc tggatacagg catgttgagc ttccgtgtga ctccaaaacc tgataaggta
    16801 gatgtctttg tgaccaagtc aaagattgac caaaatctag attttgaaga cttatcggat
    16861 ttgccagata tggaagaatt ggctcaaatg tctccagatg aatttatcaa aaccctggaa
    16921 aaaagcatcg cagacaaaac caaggatgat atcgaagcca ttcaatctct tgagcaagtt
    16981 gaagccaagg aagaagaaca agagcaggct gaacaagaag ctgagagtaa gaaagaacct
    17041 tacatctact acatcctttc ttttgctaag ttggctgact tggtagcttt tgccaagaca
    17101 gtgacttttg aaatggaaac ttctgaactc tacaaaatga acgagcgcta ttatttgacc
    17161 attttagtgg atattgaaaa tcatccaagc ccatatccag cttggctgtt ggcccgtatg
    17221 cgcgagtttg cagaggatag tgatatcagt cgctcagtct tacaagagta tggtcaagtt
    17281 ttgatgagtc acgatgcagt gctcaatctg caaaaaatcg gctaatcttt tctggaaagc
    17341 tattttcaga ttttaagaag agcgaatcgt ctgattcgtt ttttcttttt atactgaaat
    17401 agtgatttac tataatagga attttcacaa aattctgtta taatggctat attagaaaat
    17461 ttcgaggaga taaagatgac agttaaaatt gctttactag gatttggtac cgttgcaagt
    17521 ggtgtgcctt tcctcctaaa ggaaaatgga ggaaaaatca atcaatcagc acattcagat
    17581 atcaaagttg ctaaggtatt ggtcaaggat gaagatgaaa aaaatcgctt gcttgcagca
    17641 gggaatgact ttaactttgt aaccaatgtg gatgatattt tatcagacca ggatattact
    17701 atcgtagtgg aattgatggg gcgtattgag cctgctaaaa cctttatcac tcgtgccttg
    17761 gaagctggaa aacacgttgt tactgctaac aaggaccttt tagctgtcca tggcgcagaa
    17821 ttgctagaaa tcgctcaagc taacaaggta gcactttact acgaagcagc agttgctggt
    17881 gggattccaa ttcttcgtac tttagcaaat tccttggctt ctgataaaat tacgcgcgtg
    17941 cttggagtag tcaacggaac ttccaacttc atggtgacca agatggtgga agaaggctgg
    18001 tcttacgatg atgctcttgc ggaagcacaa cgtctaggat ttgcagaaag cgatccgacg
    18061 aatgacgtag atgggattga tgcagcctac aagatggtta ttttgagcca atttgccttt
    18121 ggcatgaaga ttgcctttga tgatgtagtc cacaagggaa tccgcaatat cacaccagaa
    18181 gacgtagctg tagctcaaga gcttggttac gtagtgaaat tggttggttc tattgaggaa
    18241 acttcttcag gtattgctgc agaagtgact ccaaccttcc tacctaaagc gcacccactt
    18301 gctagtgtga atggcgtaat gaacgctgtc tttgtagaat ctatcggtat tggtgagtct
    18361 atgtactacg gaccaggtgc gggtcaaaaa ccaactgcaa caagtgttgt agctgatatt
    18421 gtccgtatcg ttcgtcgttt gaatgatggt actattggca aagacttcaa cgaatatagc
    18481 cgtgacttgg tcttggcaaa tcctgaagat gtcaaagcaa actactattt ctcaatcttg
    18541 gctccagact caaaaggtca ggtcttgaag ttggctgaaa tcttcaatgc tcaagatatt
    18601 tcctttaagc aaatccttca agatggcaaa gagggtgaca aggcgcgtgt cgttatcatc
    18661 acacacaaga ttaataaagc ccagcttgaa aatgtctcag ctgaattgaa gaaggtttca
    18721 gaattcgacc tcttgaatac cttcaaggtg ctaggagaat aagatgaaga ttattgtacc
    18781 tgcaaccagt gccaatatcg ggccaggttt tgactcggtc ggtgtagctg taaccaagta
    18841 tcttcaaatt gaggtctgcg aagaacgaga tgagtggctg attgaacacc agattggcaa
    18901 atggattcca catgatgagc gtaatctctt gctcaaaatc gctttacaaa ttgtaccaga
    18961 cttgcaacca agacgcttga aaatgaccag tgatgtccct ttggcgcgcg gtttgggttc
    19021 ttccagctcg gttatcgttg ctgggattga actagccaac caactgggtc aactcaactt
    19081 atcagaccat gaaaaattgc agttagcgac caagattgaa gggcatcctg acaatgtggc
    19141 tccagccatt tatggtaatc tcgttattgc aagttctgtt gaagggcaag tctctgctat
    19201 cgtagcagac tttccagagt gtgattttct agcttacatt ccaaactatg aattacgtac
    19261 tcgcgacagc cgtagtgtct tgcctaaaaa attgtcttat aaggaagctg ttgctgcaag
    19321 ttctatcgcc aatgtagcgg ttgctgcctt gttggcagga gacatggtga ccgctgggca
    19381 agcaatcgag ggagacctct tccatgagcg ctatcgtcag gacttggtaa gagaatttgc
    19441 gatgattaag caagtgacca aagaaaatgg ggcctatgca acctaccttt ctggtgctgg
    19501 gccgacagtt atggttctgg cttctcatga caagatgcca acaattaagg cagaattgga
    19561 aaagcaacct ttcaaaggaa aactgcatga cttgagagtt gatacccaag gtgtccgtgt
    19621 agaagcaaaa taaagaatag aagataggat ggggaaactc ttgaccagag ggtttcatat
    19681 cctttttgtg aaaagaagtt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    19741 cgcaggctgc tcaaaacagt gttttgaggt tgcagataga actgacgaag tcagtaacat
    19801 atatacggta aggtgacgct gacgtggttt gaagagattt tcgaagagta ttagttaaaa
    19861 acgtgataaa ggagaaataa agatggcaga aatttatcta gcaggtggtt gtttttgggg
    19921 cctagaggaa tatttttcac gcatttctgg agtgctagaa accagtgttg gctacgctaa
    19981 tggtcaagtc gaaacgacca attaccagtt gatcaaggaa acagaccatg cagaaacggt
    20041 ccaagtgatt tacgatgaga aggaagtgtc actcagagag attttacttt attatttccg
    20101 agttatcgat cctctatcta tcaatcaaca agggaatgac cgtggtcgcc aatatcgaac
    20161 tgggatttat tatcaggatg aagcagattt gccagctatc tacacagtgg tacaggagca
    20221 ggaacgcatg ctgggtcgaa agattgcagt agaagtggag caattacgcc actacattct
    20281 ggctgaagac taccaccaag attatctcag gaagaatcct tcaggttact gtcatatcga
    20341 tgtgaccgat gctgataagc cattgattga tgcagcaaac tatgaaaagc ctagtcaaga
    20401 ggtgttgaag gccagtctat ctgaagagtc ttatcgtgtc acacaagaag ctgctacaga
    20461 ggctccattt accaatgcct atgaccaaac ctttgaagag gggatttatg tagatattac
    20521 gacaggtgag ccactctttt ttgccaagga taagtttgct tcaggttgtg gttggccaag
    20581 ttttagccgt ccgatttcca aagagttgat tcattattac aaggatctga gccatggaat
    20641 ggagcgaatt gaagttcgtt ctcgttcagg cagtgctcac ttgggtcatg ttttcacaga
    20701 tggaccgcgg gagttaggcg gcctccgtta ctgtatcaat tctgcttctt tacgctttgt
    20761 ggccaaggat gagatggaaa aagcaggata tggctatcta ttgccttact taaacaaata
    20821 aaacagagag tggggcttcc cactttcttc atttctagaa tatgaataga agggatttat
    20881 gaaacaccta ttatcttact tcaaacccta catcaaggaa tcaattttag cccccttgtt
    20941 caagctgtta gaagctgttt ttgagctctt ggttcccatg gtgattgctg ggattgttga
    21001 ccaatcttta cctcagggag atcaaggtca tctctggatg cagattggcc tgctccttat
    21061 ctttgcagta attggcgttt tagtggcctt gatagctcaa ttttactcag caaaggcagc
    21121 agtaggtttt gctaaggaat tgacaaacga tctttatcgt catattcttt ccttgcccaa
    21181 ggacagcaga gaccgtctga caacatctag tttggtcact cgcttgactt cggataccta
    21241 ccagattcag actggtatca atcaattcct gcgtctcttt ttgcgagcgc ccattatcgt
    21301 ttttggtgcc atttttatgg cttatcgaat ctcaactgag ttgactttct ggttcttagt
    21361 catggttgcc attttgacca ttgtcattgt agggttatct cgattggtca atcctctcta
    21421 cagtagtctc agaaagaaaa cggaccaact ggttcaggaa acgcgccagc aattgcaagg
    21481 gatgcgggtt attcgtgctt ttggtcaaga aaaacgagag ttacagattt ttcaaaccct
    21541 taaccaagtt tatgctagat tacaagaaaa gacaggtttc tggtctagtt tattaacacc
    21601 tctgacctat ctgattgtca atggaactct tctcgttatt atctggcaag gctatatttc
    21661 aattcaagga ggagtgctca gtcaaggtgc tctcattgct cttatcaatt acctcttaca
    21721 gattttggtg gaattggtca agctagccat gttgatcaat tccctcaacc agtcctatat
    21781 ctcagtcaag cgaatcgagg aagtctttgt tgaggctcca gaggatatcc attcagagtt
    21841 agaacaaaag caagctacca gagataaggt tttacaagtc caagaattga cttttaccta
    21901 tcctgatgcg gcccagcctt ctctgagata catttccttt gatatgactc aaggacaaat
    21961 tctaggtatc atcgggggaa ctggttctgg taaatcaagc ttggtgcaac tcttacttgg
    22021 actttatcca gtagacaagg ggaacattga cctttatcaa aatggacgta gtcctcttaa
    22081 tttggagcag tggcggtctt ggattgccta tgtacctcaa aaggtcgaac tctttaaagg
    22141 aaccattcgt tccaacttga ctctaggttt caatcaagaa gtatctgacc aggaactctg
    22201 gcaggccttg gagattgcgc aagctaagga ttttgtcagt gaaaaggaag gactcttgga
    22261 tgctctagtt gaggcagggg ggcgaaattt ctcaggtgga caaaaacaaa gattgtctat
    22321 cgcccgagca gtcttgcgcc aagctccgtt tctcatccta gatgatgcaa cctcggcact
    22381 ggataccatt acagagtcca agctcttgaa agctattaga gaaaattttc caaacacgag
    22441 cttaattttg atctctcaac gaacctcaac tttacagatg gcggaccaga ttctcctctt
    22501 ggaaaaaggt gagttgctag ctgttggcaa gcacgatgac ttgatgaaat ccagccaagt
    22561 ctattgtgaa atcaatgcat cccaacatgg aaaggaggac tagaatgaaa cgacaaactg
    22621 taaaccagac gctcaaacgt ttagccgtag atttagcaag ccatcctttc ctccttttcc
    22681 tagcctttct aggaactatt gctcaagttg gcttatcaat ttacctacct attctgattg
    22741 ggcaggtcat tgaccaagtc ctagtggctg gttcatcacc agttttttgg cagatttttc
    22801 tccagatgct cttggtggta ataggaaata ctctggtaca atgggccaat cctctcctct
    22861 ataatcgtct aatcttctct tataccagag atttacggga gcgaatcatc cataagctcc
    22921 atcgtttacc gattgccttt gtagataggc aaggtagtgg agagatggtt agtcgtgtaa
    22981 ccacggacat cgaacagttg gcagctggct tgaccatgat ttttaaccaa tttttcattg
    23041 gtgttttgat gattttggtc agtattctag ccatgctcca aattcatctc ctcatgactc
    23101 tcttagtctt gctgttgacg ccactgtcca tggtgatttc acgctttatt gccaagaaat
    23161 cctatcatct cttccagaag caaacagaga cgaggggaat tcagactcag ttgattgaag
    23221 aatcgcttag tcagcagact ataatccagt ccttcaatgc tcaaacagaa tttatccaaa
    23281 gattgcgtga ggctcatgac aactactcag gctattctca gtcagccatc ttttattctt
    23341 caacggtcaa tccttcgact cgctttgtaa atgcactcat ttatgccctt ttagctggag
    23401 taggagctta tcgtatcatg atgggttcag ccttgaccgt cggtcgttta gtgacttttt
    23461 tgaactatgt tcagcaatac accaagccct ttaacgatat ttcttcagtg ctagctgagt
    23521 tgcaaagtgc tctggcttgc gtagagcgta tctatggagt cttagatagc cctgaagtgg
    23581 ctgaaacagg taaggaagtc ttgacgacca gtgaccaagt taagggagct atttccttta
    23641 aacatgtctc ttttggctac catcctgaaa aaattttgat taaggacttg tctatcgata
    23701 ttccagctgg tagtaaggta gccatcgttg gtccgacagg tgctggaaaa tcaactctta
    23761 tcaatctcct tatgcgtttt tatcccatta gctcgggaga tatcttgctg gatgggcaat
    23821 ccatttatga ttatacacga gtatcattga gacagcagtt tggtatggtg cttcaagaaa
    23881 cctggctcac acaagggacc attcatgata atattgcctt tggcaatcct gaagccagtc
    23941 gagagcaagt aattgctgct gccaaagcag ctaatgcaga ctttttcatc caacagttgc
    24001 cacagggata cgataccaag ttggaaaatg ctggagaatc tctctctgtc ggccaagctc
    24061 agctcttgac catagcccga gtctttctgg ctattccaaa gattcttatc ttagacgagg
    24121 caacttcttc cattgataca cggacagaag tgctggtaca ggatgccttt gcaaaactca
    24181 tgaagggccg cacaagtttc atcattgctc accgtttgtc aaccattcag gatgcggatt
    24241 taattcttgt cttagtagat ggtgatattg ttgaatatgg taaccatcaa gaactcatgg
    24301 atagaaaggg taagtattac caaatgcaaa aagctgcggc ttttagttct gaataagcca
    24361 ttctcttttg aaagtttatg gacgaaaaaa gttgccttcg agtgactttt ttgttacaat
    24421 agctagaaaa attgttcact gtaatactca atgaaaatca aagagcaaac taggaagcta
    24481 gccgtaggtt gctcaaagca cagctttgag gttgtagata agactgacga agtcagttca
    24541 aaacactgtt ttgaggttgc agatagaact gacgaagtca gctcaaaaca ctgttttgag
    24601 gttgcagata gaactgacga agtcagtaac cacacctacg gcaaagtgaa tctgaagtgg
    24661 tttgaagaga gtacaacttg tcttttagaa aaggagccta taatgaaagt ctttcagcat
    24721 gtaaatatcg tgacttgtga tcaagatttc catgtttatc ttgatggaat cttagcagtc
    24781 aaggattctc aaatcgtcta tgtcggtcaa gataagccag cgtttttaga gcaagctgag
    24841 cagattatag actatcaggg agcttggatt atgcctggtt tggtcaattg tcacacccat
    24901 tctgcaatga caggtctgag agggatccga gatgacagca atctccatga atggctcaat
    24961 gactatattt ggccagcaga atctgagttt actcccgaca tgactaccaa tgcggtcaaa
    25021 gaagccctga cagagatgct ccagtcagga acaacaacct ttaacgatat gtataatccc
    25081 aatggtgtgg atatccagca aatttatcag gtggtgaaaa cttccaagat gcgttgttat
    25141 ttttctccga ctctcttttc ttcagagaca gaaacaactg ctgagactat aagtagaact
    25201 cgatccatca tagacgaaat cttaaaatat aaaaatccaa atttcaaggt tatggtagca
    25261 cctcattctc cgtatagctg cagtagagac ttgctggaag cgagtttgga aatggcaaaa
    25321 gagctaaata ttccgctcca tgtccatgtg gcggagacca aggaggagtc aggaattatc
    25381 ctcaaacgat acggcaaacg cccccttgct tttcttgaag aactgggtta tttagatcat
    25441 ccgtccgtat ttgctcacgg ggtcgaatta aacgagagag aaattgaacg cttggcatct
    25501 tctcaagtgg ctatcgccca caatcctatc agtaacctca aactggcatc aggaattgct
    25561 ccaattatcc agctccaaaa agcgggagta gcagtcggaa ttgcgactga ctcggttgct
    25621 tccaataaca atctagatat gtttgaggaa ggaaggactg cagctcttct tcagaagatg
    25681 aaaagtgggg atgccagcca gtttccaatc gaaacagctc tcaaggtact gacaatcgaa
    25741 ggggctaagg tccttggaat ggaaaatcag ataggaagtc tggaagtcgg caagcaagca
    25801 gattttctgg tcattcaacc acaagggaaa attcatctcc aacctcagga aaatatgctg
    25861 tctcacctgg tttatgcagt taaatctagt gatgtagatg atgtttatat cgccggagaa
    25921 caggttgtta agcaaggtca agtcctgaca gtagaacttt aaaagaaaaa ttacgaaaaa
    25981 ttttaaaaaa agtttgcaaa aatcttgcat tctttttttg actatgctat acttatatac
    26041 ggtttaaaaa aactgcctaa gacagtaggg gagctcgact cataaatatc ctaccgagga
    26101 caaaacgtat catgtaaaaa gaagcgtatt gtactttcgt gtctaggttt gggcgcgttt
    26161 ttctttttga aaaattcccc aagcaaaata attacggagg tgaacacact aatgagtgaa
    26221 gcaattattg ctaaaaaagc ggaactagtt gacgtagtag ctgaaaaaat gaaagctgct
    26281 gcatctatcg tcgttgtaga cgctcgtggt ttgacagttg agcaagatac agttcttcgt
    26341 cgtgagcttc gtggaagcga agttgagtat aaagttatta aaaactcaat cttgcgtcgt
    26401 gcagctgaaa aagctggtct tgaagatctt gcatctgtat ttgttggacc atctgcagta
    26461 gcattttcta atgaagatgt tatcgcacca gcgaaaatct tgaacgactt ttctaaaaac
    26521 gctgaagcac ttgaaattaa aggtggtgca atcgaaggcg ctgtcgcatc taaagaagag
    26581 attcttgcac ttgcaactct tccaaaccgc gaaggacttc tttctatgct cctttctgta
    26641 cttcaagcgc cagtgcgcaa cgttgctctt gcagtcaaag cggttgcaga aagcaaagaa
    26701 gacgcggctt aatcttaagc tacacagcgt agcctagcta cgaaaaaaac tattataaaa
    26761 tttaaaactt atttggagga aataacaatg gcattgaaca ttgaaaacat tattgctgaa
    26821 attaaagaag cttcaatcct tgaattgaac gaccttgtaa aagctatcga agaagaattt
    26881 ggtgtaactg cagctgctcc tgtagctgtt gctgcagctg atgcagctga tgctggtgct
    26941 gctaaagatt cattcgacgt tgaattgaca tctgcaggcg acaaaaaagt tggcgttatc
    27001 aaagttgtac gtgaaatcac tggtcttggt cttaaagaag ctaaagaact tgttgacggt
    27061 gcaccagcac ttgttaaaga aggcgttgca actgcagaag ctgaagaaat caaagctaaa
    27121 ttggaagaag ctggagcttc agttactctt aaataataga gtatcgcaat ttgattgcgg
    27181 aatccctatt taccagtctt tgagagcgat aagcgattga tagaaactga taaattgatt
    27241 tggtttcctg ccaaaaattc tttggcagga tttttgtttt aataaacttt cgggggtaga
    27301 cactagattg tctacccctt tttttgtgtt tcggaggtaa ttatgcaaaa ggaaggacag
    27361 tcatcacgtc aattcgtgaa gagtcatctc atgactatca tgggagttga tattgtaaaa
    27421 gcaactcagt tagttgatga aatggaacaa gtaggtttaa tccgatttga tgaatttgga
    27481 aatgttggaa ttttagtctt ggagggacaa taatgaagcg tattaccgct aatcaatatc
    27541 agacatcaga gcgttattat aagctcccca aacttttatt tgagagtgaa cggtataaga
    27601 atatgaaact ggaggttaag gtggtttact cagttttaaa agatcggttg gagttgtctt
    27661 tgagcaaagg ttggattgat gaggatgggg ctatttattt gatttattcc aattcaaatt
    27721 tgatggcact tttaggctgt tcaaagtcaa aattactctc catgtgagtt tgaagtgata
    27781 tttttagatg attaccataa aaaacataac tacccactat tttacgaatc ctatcttcaa
    27841 aacgttatgg aattccttga aagtcaagac ataaagaatg gggttgatgc ctttgtagat
    27901 gatcatcaaa atctcgtttt tgttttatat ggacaaggct atcgagccga gggaaaagag
    27961 ggaatactta caacccaagt aactgtaaaa gcttatgatg aagacaagaa accgattaac
    28021 ttcgcaaatt tattagattc cttaatttat tagattcctt aatcgtgtca gaatatcaaa
    28081 tggaaccgaa tctttgggag gtctcccatg attgatctct atctaagtaa aaatagacaa
    28141 agaaatcaac ttcttttaga tttcttccaa aactatggca tagaggtatc ttgtcattca
    28201 gtttctgaaa tgacaaagga caaattaatt gagatgatga gctattcttc agattgtttt
    28261 gagtttttat ctcccaattt attacgattt aagaaccgtg acaatctaag attaacggat
    28321 ttcgttgaga taattttaaa aaatcctgaa ctaaccatca gacttcctct tgcggtttca
    28381 aataagcgag tttatccaag tctgaatttg gaagaggcta gagctctatt gccaagagat
    28441 acgaaacaat tgatttacat ggcgcaaaca cattatttat ctaactaaag gagaagcaat
    28501 atggctgaac gattttggga gaacttgtcc attattttgg ctgaaagaaa tatcagctgg
    28561 attgagttaa ccagaaaaat gtttgcggga gagtttcact atccaagtga attgaatcgt
    28621 ttgtatcaaa agattcgcca ctagaagatg gaacaatgaa tgcctcaaag tccatgggta
    28681 gaaaggattg tgcaggtatt agatttagat tatgaagatt tatttcggag gtaactatga
    28741 aaagaataat tccagtttat atattccaac aagtaaatgt cctattggta tctctatact
    28801 tattgaaatt tctttgtatc ggtgagttaa ctatactaca gattctctat ggttcgtcac
    28861 tcatttcttt tttatggatg tatggccaac gcaaacaagc gcataaggtc aatatgaaat
    28921 ctaggatgaa atggcttggt gttgaatttg ttagcctact gattataagt ctatgtttta
    28981 gtctgattca tgctcaagga agcacgaatc aagcaaactt aattggcctt caacatcaaa
    29041 ttccttggtt ttcattttta ttgttcttaa tcaatgcgag tatggttgaa gaatttctgt
    29101 atcgagaaat tttatggaat ttggtcagaa aattagatat cagagttgct ttgacaagtg
    29161 ttttatttgc cttagcacat catccaggaa ccattatagc ttggtgtttg tatgtatcgc
    29221 tggggatgtt tttagggctt gtacgctaca aattggactt atggggcagt atggggctac
    29281 atttggtgtg gagcctacta gtttatagtt tgctgctttt ttaaaatagg taacctgatt
    29341 tttaggtaac ttctaaaact aacttccagt tttgggagag agatggaagt tactttgaaa
    29401 agttacggaa acattatttt ctacgtgaca acattgtatc attgcttgca ttttactgct
    29461 ggagagagta taatgaaggt ggataaagca cttaatccca aaaatttaaa taggaggagt
    29521 tagctatggc agaagaagta ttaaatcttc aattagtatc tgttcaagtt gacgaaacag
    29581 atgaagttga tggaatgcga tttagtacat tcagtacaaa ccgttgcggt aactggagtg
    29641 cttttagttg ggaaaattgt taattcattt aaattgtaaa cttt
//
LOCUS       DAVLZG010000022        29421 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLZG010000022 DAVLZG010000000
VERSION     DAVLZG010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.022"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..508
                     /locus_tag="VYO72_000944"
     CDS             <1..508
                     /locus_tag="VYO72_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707342.1"
                     /translation="KLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDWNYSDL
                     VMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLNFFYKQ
                     LGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSFSNEYL
                     KTTDEVNR"
     gene            505..1683
                     /locus_tag="VYO72_000945"
     CDS             505..1683
                     /locus_tag="VYO72_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1707343.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            2108..2341
                     /locus_tag="VYO72_000946"
     CDS             2108..2341
                     /locus_tag="VYO72_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1707344.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            2624..4573
                     /gene="mutL"
                     /locus_tag="VYO72_000947"
     CDS             2624..4573
                     /gene="mutL"
                     /locus_tag="VYO72_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1707345.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(4898..5365)
                     /locus_tag="VYO72_000948"
     CDS             complement(4898..5365)
                     /locus_tag="VYO72_000948"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1707346.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(5366..6571)
                     /locus_tag="VYO72_000949"
     CDS             complement(5366..6571)
                     /locus_tag="VYO72_000949"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1707347.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(6591..7226)
                     /gene="ribE"
                     /locus_tag="VYO72_000950"
     CDS             complement(6591..7226)
                     /gene="ribE"
                     /locus_tag="VYO72_000950"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1707348.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(7211..8311)
                     /gene="ribD"
                     /locus_tag="VYO72_000951"
     CDS             complement(7211..8311)
                     /gene="ribD"
                     /locus_tag="VYO72_000951"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1707349.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(8445..8559)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8716..9309
                     /gene="ruvA"
                     /locus_tag="VYO72_000952"
     CDS             8716..9309
                     /gene="ruvA"
                     /locus_tag="VYO72_000952"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1707350.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            9319..9882
                     /locus_tag="VYO72_000953"
     CDS             9319..9882
                     /locus_tag="VYO72_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1707351.1"
                     /translation="MTKRCSWVKMTNPLYITYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            9879..10556
                     /locus_tag="VYO72_000954"
     CDS             9879..10556
                     /locus_tag="VYO72_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707352.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALIHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(10693..11723)
                     /locus_tag="VYO72_000955"
                     /pseudo
     CDS             complement(10693..11723)
                     /locus_tag="VYO72_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
     gene            complement(11978..12661)
                     /locus_tag="VYO72_000956"
     CDS             complement(11978..12661)
                     /locus_tag="VYO72_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1707353.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(12673..13617)
                     /locus_tag="VYO72_000957"
     CDS             complement(12673..13617)
                     /locus_tag="VYO72_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1707354.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            13749..16580
                     /gene="uvrA"
                     /locus_tag="VYO72_000958"
     CDS             13749..16580
                     /gene="uvrA"
                     /locus_tag="VYO72_000958"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1707355.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILASVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            16573..17634
                     /locus_tag="VYO72_000959"
     CDS             16573..17634
                     /locus_tag="VYO72_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1707356.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            17766..18164
                     /gene="spx"
                     /locus_tag="VYO72_000960"
     CDS             17766..18164
                     /gene="spx"
                     /locus_tag="VYO72_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1707357.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            18230..18799
                     /locus_tag="VYO72_000961"
     CDS             18230..18799
                     /locus_tag="VYO72_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1707358.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            18886..19152
                     /locus_tag="VYO72_000962"
     CDS             18886..19152
                     /locus_tag="VYO72_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1707359.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            19156..19575
                     /gene="ruvX"
                     /locus_tag="VYO72_000963"
     CDS             19156..19575
                     /gene="ruvX"
                     /locus_tag="VYO72_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1707360.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            19591..19896
                     /locus_tag="VYO72_000964"
     CDS             19591..19896
                     /locus_tag="VYO72_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1707361.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            20155..21405
                     /locus_tag="VYO72_000965"
     CDS             20155..21405
                     /locus_tag="VYO72_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1707362.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKDGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMREGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            21402..21944
                     /locus_tag="VYO72_000966"
     CDS             21402..21944
                     /locus_tag="VYO72_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1707363.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            22090..23622
                     /gene="cls"
                     /locus_tag="VYO72_000967"
     CDS             22090..23622
                     /gene="cls"
                     /locus_tag="VYO72_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1707364.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIMEIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            23700..23843
                     /locus_tag="VYO72_000968"
     CDS             23700..23843
                     /locus_tag="VYO72_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707365.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            23880..25418
                     /locus_tag="VYO72_000969"
     CDS             23880..25418
                     /locus_tag="VYO72_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1707366.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     YFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILY
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            25538..27745
                     /gene="nrdD"
                     /locus_tag="VYO72_000970"
     CDS             25538..27745
                     /gene="nrdD"
                     /locus_tag="VYO72_000970"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1707367.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTD"
     gene            27757..27897
                     /locus_tag="VYO72_000971"
     CDS             27757..27897
                     /locus_tag="VYO72_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707368.1"
                     /translation="MGKYQLDDKGCAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            27941..28447
                     /locus_tag="VYO72_000972"
     CDS             27941..28447
                     /locus_tag="VYO72_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707369.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            28440..29030
                     /gene="nrdG"
                     /locus_tag="VYO72_000973"
     CDS             28440..29030
                     /gene="nrdG"
                     /locus_tag="VYO72_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1707370.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            29038..29208
                     /locus_tag="VYO72_000974"
     CDS             29038..29208
                     /locus_tag="VYO72_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1707371.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNPNYSPQI"
BASE COUNT         8724 a         5483 c         6313 g         8901 t
ORIGIN      
        1 aaagttgaaa aattttattg aagaggaatt caataaattt agaaattctc acggagctaa
       61 tctaagcctc tatgaatact gtttgcttga taattcttta actttaaaaa atgattggaa
      121 ctattctgat ttagttatga aatttacgag taatttttat gctgatataa aagacttgtt
      181 catggaaaat tctgatattg aaatcatcca tgaagaggga gtaccttttg tatttttaga
      241 tttaataggt gaaggtaaaa aagaatatga aatgtttttt caatggttaa acttctttta
      301 caaacagctt ggaatcacat tgtatgctag aaatagtttt gggtttcgga atctaacagt
      361 agagtatttt ggaattattg ggacagaaag atatatattt aagatttgtc caggtgttta
      421 taaagggtta agttattatt tgatgaaatt tttattaaaa tctttttcaa atgaatattt
      481 aaaaactact gatgaggtta atagatgaaa aatttgataa agttgctaat aattagattg
      541 attgttaact tagcagacag tgtattttat atagtagcat tgtggcacgt tagcaataat
      601 tattcttcga gcatgttctt aggaatattt attgcagtaa attatctacc ggatttgtta
      661 ctaatctttt ttggaccagt tattgacaga gtaaatccgc aaaaaattct tataatatca
      721 attttggttc aattagcagt ggctgtaata tttttattat tattaaacca aatatcattt
      781 tgggtgataa tgagtctagt gtttatttca gtaatggcta gctccataag ttacgtgata
      841 gaagatgtgt tgattcctca agtggtagaa tatgataaga ttgtatttgc aaattctctt
      901 tttagtattt cgtataaagt attagattct atttttaatt cattcgcatc atttttacag
      961 gtggcagtag gatttatttt attggttaag atagatatag gcatattttt acttgctcta
     1021 tttatattgt tgttgttaaa atttagaact agcaatgcga atatagaaaa cttctctttc
     1081 aaatattaca agagagaagt gttgcaaggt acaaagttta ttttaaataa taaattatta
     1141 tttaaaacca gtatttcttt aacgcttata aacttttttt attcatttca gacagtagtt
     1201 gtaccgattt tttctattcg atattttgat ggtccgattt tttatggtat ttttttaact
     1261 attgctggtt tgggtggtat attgggaaat atgctagcgc caatcgtaat aaaatattta
     1321 aaatcgaatc aaattgttgg tgtatttctt tttttgaacg gctcaagttg gttagtagca
     1381 attgttataa aagactatac tttatcactt attttatttt tcgtttgttt tatgtctaaa
     1441 ggagtcttca atattatttt taattcgttg taccaacaaa tacctccaca tcaacttctt
     1501 ggtagggtaa atactaccat tgattctatt atttcttttg gaatgccaat tggtagttta
     1561 gttgcaggaa cgcttattga tttgaatatt gaattagtgt taattgctat tagcatacct
     1621 tattttttgt tttcttatat tttttatacg gataatggat tgaaagaatt tagtatatat
     1681 tagaaatgtt tatgttcatt caaaagcata atgactataa ctgaaaaaga aaagtgatat
     1741 ctttaaggtt gttcttcttg gtggtgagat tcgtgagaca acccaagctt ttgtcggaaa
     1801 gattaccaat gctttgatgg ataggatgta ctttagcaag atgtttttag tggtaacggt
     1861 atcgtggatg gacgtgtaat aacctcttct ttcgaggagt attttactaa aaaactagcc
     1921 ttggagcgtt ccccagaaac ggacttactc attgactctt caaagatttg gggagaagat
     1981 tttgcttcat ctgttccttg aaaaaagtca cagcagtcat cacagacgat agtactgaac
     2041 aaaactatga agagttagaa atttatacgc aggtgattgt ataaaggatc tggaaataga
     2101 taagaagttg attagtattg acctaggtgg tacaaatatt aagattactg ttctttcaaa
     2161 tgacggtgag attgaaactt tgtggagtat tacaacagat acaagtgaga aaggttctca
     2221 aattatatcg gacatcatca gttctattaa aaataaattg accgaacgga atattcctga
     2281 tagcgacctt cttggaatcg gtatgggaag ttgctcatca tactttcctt gtaaatcata
     2341 ggggctataa actctccgtc tacttgtcct gcaacaattg aagtctgctc aaaacgccgt
     2401 ccgctaatct tttcatagac tttctccctt ttaggagcct agctttctag tttgttcttt
     2461 gatttttatt gagtatacca ctattttact ccctctggca agggactttg tctatgtgga
     2521 gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg tataatagca
     2581 ctaatcaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc atattattga
     2641 attgccagag atgctggcaa accaaatcgc ggctggagag gtcattgaac gtcctgccag
     2701 tgtggtcaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga ttatcattga
     2761 gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg gaattgccca
     2821 cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa atcaagcaga
     2881 tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta ttgcgtctgt
     2941 tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca agttagtcgc
     3001 gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa ccaaggtttg
     3061 tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga gccagcaagc
     3121 ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc ctgagatttc
     3181 ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg gtcaattgcg
     3241 ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg aaattgagaa
     3301 ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga ctcgggctaa
     3361 ccgcaattat atcagcctct tcatcaatgg ccgttatatt aagaacttcc tgctcaatcg
     3421 tgctattttg gatggttttg gaagcaagct tatggttgga cgttttccac tggctgtcat
     3481 tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta agcaagaggt
     3541 gcggatttcc aaggaaaaag aactgatgac tctggtttca gaagctattg caaatagtct
     3601 caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga ccgtgcgcaa
     3661 tcgtgagaag gtggagcaaa ctattctccc actcaaagaa aatacgctct actatgagaa
     3721 aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag aattgactga
     3781 tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga ccaagccagc
     3841 aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc atccagagtt
     3901 agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag catccagctt
     3961 cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc aagggcgaga
     4021 tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg aggagtaccg
     4081 tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct atatctttga
     4141 atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag aggaagtggg
     4201 cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc ctatttggat
     4261 ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc ttttgaccaa
     4321 ggaagtttct atcaagaaat accgagcaga gctggctatc atgatgtctt gcaagcgatc
     4381 tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct atcagctttc
     4441 tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc attttaccaa
     4501 gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc tccgtgagtt
     4561 ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag aaaaacgcat
     4621 aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catagaaata tttacttcat
     4681 tttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca gtaatctcaa
     4741 aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg tgttttacca
     4801 ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa ttgcgatttt
     4861 gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat gtacgaatta
     4921 ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct gctttagtac
     4981 cagctcgttc tatggcttgt tcaattgtat ctgtcgttaa cacaccaaac ataacaggaa
     5041 tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat acataatcat
     5101 aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca tattttttac
     5161 tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc caggctacct
     5221 cgatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca gataataatt
     5281 ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata ttgtttgcta
     5341 ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg tgacccattc
     5401 gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt tcgattgata
     5461 ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca ggattatttg
     5521 tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca atatgatatt
     5581 ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc atgccttgat
     5641 cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc tcctgtcgca
     5701 agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta tcgaattgct
     5761 gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg gagtggaccc
     5821 gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga tgatgttccc
     5881 catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta ggcatattga
     5941 cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt aattctttga
     6001 tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct gttctcatca
     6061 ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt ccagctaatt
     6121 ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca cctttttttg
     6181 caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata tcttcagcta
     6241 cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc gtttctttat
     6301 aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca accataggtg
     6361 aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat cctttggcat
     6421 aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa attaagtctc
     6481 cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc tgcaatgctt
     6541 ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg ctaaaatcca
     6601 ttttgatata atagttcctt agatatttct gattttggag agttatccat cagtttttgc
     6661 acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg tttactctta
     6721 agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac tttggagact
     6781 ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac tattaaatct
     6841 aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt ttttattgac
     6901 gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag tcgaccgttg
     6961 acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt aagagctgtt
     7021 cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa atgagtaact
     7081 gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt taatattttt
     7141 gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc aacttttccg
     7201 atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg agatagtcat
     7261 ttcctatttg agaaaaagca taaggtttca atctaatagc gtcatttggc aaagaaatgc
     7321 cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca atatatattt
     7381 tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg cccccttcta
     7441 gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat aagtctatat
     7501 gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat agcttcattt
     7561 tatttttgtc ttcagaggaa gtggcaatgt aagttttaat atcatttgct gtttttacga
     7621 ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata ggatttttcc
     7681 cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg actcccacca
     7741 taattgcact aacatagtgt cgtaactgat gcacatgctt tcttgcttct tcttcagtaa
     7801 tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt gcatatttca
     7861 taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt aagttaagac
     7921 actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt atctttactc
     7981 cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt gtaataccac
     8041 tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag ggttcaagtg
     8101 ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca tttctctcag
     8161 catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta tcttttacaa
     8221 taactgcgcc gaccatagga ttgggattga cgtaaccagc ccctttttgt gccagtttta
     8281 ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa tataccttga
     8341 ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa atgctctgaa
     8401 atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat cttctttcat
     8461 ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct cgtgggctat
     8521 accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca gatgattata
     8581 gtacttaatt ttgaatatgt caacagataa ataccgattg tttttgatat actgtatttg
     8641 tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata aacgaaataa
     8701 gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat tactgccaaa
     8761 tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa tccttatgcc
     8821 tattcaggtc aggttaatca ggaggctcag atttatgtgc atcaggttgt gcgtgaggac
     8881 gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct tagtctgatt
     8941 tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga tgacaatgct
     9001 ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt ccctaaaatt
     9061 ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt agttgcagga
     9121 gatgaccttc ctgccaaggt cgcagtgcaa gcaagtgctg aaaaccaaga attggaagaa
     9181 gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa aatcaagaaa
     9241 ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct taaaatgttg
     9301 gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac caacccgctc
     9361 tacatcacct atcatgatga ggagtggggc cagcccctcc atgatgacca agcattgttt
     9421 gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt actcaacaaa
     9481 cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc agagatgact
     9541 gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag agccaagatt
     9601 tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta cggctctttt
     9661 gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt tcctgattat
     9721 cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct caaaaaacga
     9781 ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc agggctagtt
     9841 gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac aaaaataagg
     9901 gaattctgat ttttgcgatt ctctatacag tcctctttgt gtttgatggc gttaaattgc
     9961 tggcttcttt aatgccatct gccattgcaa attatcttgt ttatgtagtt ttagctttat
    10021 atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt agaaagacta
    10081 aaagaaaatt cttctttgga gtcttaacag gatggctctt tctcattctg atgactgttg
    10141 tctttgaatt tgtatcagag atgttgaagc agtttgtggg actagatgga caaggtctaa
    10201 atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct gtttttgctt
    10261 gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg cattacttgc
    10321 aggaacggtt gtcaggttta ctaagcatta ttctggtagg acttgttttt gctctgattc
    10381 atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta ggtggaggcc
    10441 ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc ctacttgttc
    10501 acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta aaatgaaatg
    10561 agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt
    10621 caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa agctgagaaa
    10681 cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg catctacatg
    10741 agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat tcagattata
    10801 gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt cgtcatggaa
    10861 agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata tgccagtgtc
    10921 ctttaaagtt agcaacatct ttttgaagtc ttctggctta ggcttttctt cgcttgtttc
    10981 gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt atttttggca
    11041 gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg attcgaggca
    11101 accaccgagg attttcccct cgaactgggc acttccttgc aacaagtcaa aacctgtatt
    11161 tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc gttcctcata
    11221 ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc tcaatcaatt ctttaaagta
    11281 gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta aaaaggattg
    11341 accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg ttgtatccga
    11401 gaagccaaga aaaatttttt gtttgatacc cttttggagt tggtcatttt caaaaagata
    11461 aggtagcaag cgataggcat cgtctccacc gatggcacat aggatcatgt cgatctatca
    11521 tcagaaaagg catgaatcaa atcctctgca cgagcttcag gatggtcctt gataaagtct
    11581 aatcctttta acgaatgggg caaaaagatg ggattgagtc ccagatcctt gagacgttgg
    11641 atacccaagt ccacttcgtg tttgacaaaa tcctctccga taatgccact agataaacta
    11701 acaataccaa tagtagaaac catatctcat cctcctagaa atagattgag cctattttat
    11761 cacaaaatat aagagaaagc tatgtgggat ttcagaagaa tacttttaat actcttcgaa
    11821 aatctcttca aaccacgtca gttttatttg caacctcaaa gctgtgcttt gagcaacctg
    11881 cagctagctt cctagtttgc tctttgattt tcattgagta taactcaaaa aagtaagtga
    11941 aaaagcaacc gcacctgcag ttgcttttat cgttttctta ttcttgatag cgtgttggtc
    12001 ctgcacttgc actacggata ttcaagcgtt tcttgagata gaagcgaagg gctaggaggg
    12061 ctgctccaat aatagctagt ggcaatggat ccagtactgg gttaaggcta gctggtagga
    12121 agcttgttgc aaagaagaca agcaaccaaa ggaacataga agctaggata actagtacag
    12181 atttccagaa aggtggacgt tgactgcgat ccatatctgg tccatagtat tggtaaacaa
    12241 agtagtacat caagtagaag gcaaatccac caaccagtcc aactaataga agagtaatca
    12301 atccatagcc gaaagcttga tctgccgcaa agaaggttgt gagggcgctg acaagggcaa
    12361 agaggctagt gatgaaaaga gctgagtcca taatcatcag ttttggatca tcattttctt
    12421 ttggatgctc tttttcgtac tgctctttga cagtgaagct atgagcccaa tgagttggtg
    12481 cgccgtatag ggaacgggca gttgtacctt tagattgctc ctcaaggatt tggggaatga
    12541 cttcctcaaa aatagtctgg atttcagcgt ctgttttccc atctttgatg aattgttggg
    12601 tagcaatgtg gacaaactct tggtttttct tagttaattt ttgtagatca atttgagaca
    12661 taggaactcc tcttagaacc attttttatg gatgagatag agagtgagcg agacactcat
    12721 agcaaaggcg ataaagacga ttaaccagaa ggcatttggc tctccgttta gggggatttc
    12781 attatcctta aagttcatcc cgtaggcaga aaagaccatg gttgggatgg acatgacgat
    12841 ggtcacaagg gccaaggttt tcatgatgtt gttctggttg ttagaaatga tagaggcaaa
    12901 ggtctctgtc atagaatgca agacgtttcc ataaatatct gccatctcga tggcctgttg
    12961 ggtttcaatc agggtgtctt caagcaggtc ttcgtcttca aggtatttct tgatattgct
    13021 ggttgaactg gtcaatttct taatcacgcg ctcatttgtt ttgagggagg ccttgaaata
    13081 gacgatagtt ttttccaatt ccatgagctc aatcaattct tcattacgag ttgattgatg
    13141 cagttgactt tcgatttgtt cactcttgcg gtcgattgaa cgaagggctg ttaggtaaag
    13201 ctctgcattg cgataaagaa tttgaaagat aaaacgtgaa cgcatgaagg tatagaaatt
    13261 acgcaatcga cggttgataa agacatcaag gacaggtagt ggttccaaac acgtagtgat
    13321 aatggtttcc tcagtgatga taataccaag cgggatggtt acgtagtagg tgcggttatt
    13381 tctttcctcc gtgaccggca cgtctacgat aatcagggta tactcgtctt caatggtaat
    13441 acgagacatt tcttccgcat cgagcggtgc tcgaaggtcg gcaatatcaa tatcgaaggt
    13501 gttggcgatt tcgagtgatt cattttgagt cggattgacg agattgatcc aagtacccgg
    13561 ttcaagcgta tcgatctctt taaattcagt tgttgtagag agaaaaactt gtttcatatc
    13621 ccttatcctt tctcattttt cagatttttt cacactgtac tattatacta caaaatcggc
    13681 cttttgggta atagaatctc actttttttg gtataatggt aagcaataat ggactagaaa
    13741 gaacaaagat gcaagataaa attgtcattc atggggcgcg tgcccataat ttaaaaaata
    13801 ttgatgtgga gattccgcga gacaagttgg ttgtcgtgac tggcttgtca ggttcaggga
    13861 agtccagtct ggcttttgat accctctatg cggagggaca acgtcgctat gtagagagtt
    13921 tgtccgccta cgctcgtcag ttcttgggaa atatggaaaa accagatgta gatgccattg
    13981 atggtctcag tccagctatt tctatcgacc agaaaacgac tagcaaaaac cctcgctcga
    14041 cggtgggaac aacgactgaa atcaatgact atctgcgtct cctctacgca cgtgtgggga
    14101 cgccttactg tatcaacgga catggagcta tcaatgcttc ttctgtggag caaatcgttg
    14161 ataaggtttt ggagttacct gaacgccagc gcttgcagat cttggcctct gtcatccgca
    14221 agaaaaaagg ccaacataag agtgttatcg agaaggttca gaaagacggg tatgttcgtg
    14281 tccgtgtgga tggggaagtc tatgatgtga ccgaagtgcc agagttgtct aagagcaagc
    14341 aacacaatat cgatgtcgtg gttgaccgta ttgttatcaa ggagggcatt cgtagtcgtc
    14401 tctttgattc cattgaggct gcccttcgta ttgcagaagg ttatgtcatt atcgacacca
    14461 tggacgactc tgagttgttg ttctctgagc attatgcctg tccagtttgt ggttttactg
    14521 tcccagagtt agagcctcgt ctcttctctt tcaatgctcc ttttggctct tgtagtgagt
    14581 gtgacggctt gggcatcaag ctggaggtgg atactgattt ggtagtgcca gatgccagca
    14641 aaaccttacg tgagggagcg ttagcacctt ggaatcctat ctcatccaac tactatccaa
    14701 acatgttaga gcaggccatg aaagtatttg gagtggctat ggataagcct tttgaggacc
    14761 tgtcagaaga agataagaac ttgattctct atgggtcaga tggtaaggaa ttccatttcc
    14821 actatgagaa tgaatttggt ggcgtgcgcg atatcgacat tccgtttgag ggagttatca
    14881 ataatatcaa acgtcgttac catgaaacca atagcgatta cactcgcact cagatgcgtc
    14941 tctacatgaa tgagctgacc tgcggaacct gtcaaggcta tcgtctcaat gaccaggcct
    15001 tgtctgtccg tgtgggcggc cagcaagggc cacatattgg agaaatctca gacctgtcta
    15061 tcgctgacca cttggacttg gtgagccagt taactttgtc tgaaaatgaa gccatcattg
    15121 ctcgtcccat tctcaaggaa atcaaggatc gtttgacctt ccttaataat gtgggtctta
    15181 actatctaac cctgtcacgt tcagcaggaa ccctttcagg tggggaaagt cagcgcattc
    15241 gtttggcaac ccagattggt tccaacctat caggcgtcct ctatatccta gacgagccgt
    15301 caatcggtct tcaccagaga gacaatgacc gcctgattgc cagtctgaaa aagatgcgtg
    15361 acttgggcaa tactcttatc gtggtggaac acgacgaaga taccatgcgt gaagctgatt
    15421 atctgattga cgttggtcct ggtgccggtg tttttggtgg tgagattgtt gcagcaggta
    15481 cacctaagca agtggctcgc aacagcaagt ctatcacagg tcagtacttg tcaggcaaac
    15541 gtgtcatccc agtaccagaa gagcgccgtg tcggaaatgg tcgttttatt gaagtgatag
    15601 gagcgcgtga gaacaacttg caaaatgtca cggctcgctt tccactagga aaatttatcg
    15661 cagtgacagg tgtgtcgggt tcagggaaat cgactctaat caacagcatt ctcaaaaaag
    15721 ccattgccca gaagctcaac cgtaattcag acaaacctgg taagtttaag actattacag
    15781 ggattgagca tgtcgaccgt ttgattgata ttgaccagag ccctatcgga cggacgccga
    15841 ggtctaaccc agctacctat acaggagttt ttgacgatat acgtgacctt tttgctcaga
    15901 caaatgaagc caagattcga ggctacaaga aggggcgctt cagtttcaac gtcaagggag
    15961 gtcgctgtga agcttgctca ggtgacggga ttatcaagat tgagatgcac ttcttgccag
    16021 atgtttatgt ggcttgtgaa gtttgccacg gaacccgcta taacagtgaa accctagaag
    16081 ttcactacaa ggaaaagaat atttcgcagg tcttggatat gacggtcaac gatgcggtag
    16141 aatttttcca acacattccg aaaattcaac gcaaactcca gaccatcaag gatgtagggc
    16201 taggctatgt gaccttggga cagccagcta ccaccctttc tgggggagaa gcccaacgta
    16261 tgaagttagc tagcgaactc cacaaacgct cgacaggaaa atctttctac attctggatg
    16321 agccgacgac agggcttcat acagaggaca ttgctcgcct gctcaaggtt ttagctcgct
    16381 ttgtagacga tggcaataca gtcctcgtca tcgagcacaa tctggatgtt atcaagacgg
    16441 cagaccatat cattgacttg ggacctgagg gcggtgtcgg tggtggaacc atcatcgtaa
    16501 caggaactcc agaagaagta gctgccaatg aagccagcta tacaggacac tatttgaaag
    16561 gaaagttaca tcatgaataa acgcgtacaa gcatttctag ctaaaatgca agaaaaagaa
    16621 ctagatggta tcatcatcaa caatcttaaa aacgtctatt atttgactgg tttttggggc
    16681 tcaaacggaa cagtctttat cagccgtgac cgtcaggtct tagtgacaga ctctcgctat
    16741 atcatcgcag ctaagcaaga aaccagtggt tttgagattg tggctgatcg tgatgaattg
    16801 gctgtcattg caggaattgt taaggacatg ggcttgactc gtatcggttt tgaagatgag
    16861 atttcagtat cttattacca ccgtatgcag gcagcttttg caggtttgga cttgcttcca
    16921 caaactcaat ttgtggaagg tcttcgtatg attaaggatg aggcagagat tgcagcgatt
    16981 cgcaaggctt gttctatctc agaccaagct ttccgcgatg cgcttgactt tatcaaacca
    17041 ggaaaaactg aaattgaaat tgccaacttc cttgatttcc gcatgcgtga gttgggagca
    17101 tctagcttat cttttgatac gatcctagct agcggtatca attcttctaa accccatgcc
    17161 catccaatgc acaaaccagt ggagttggga gaagccatta ccatggactt cggctgtctc
    17221 tatgaccact atgtcagtga tatgacccgg actatctatc tagggcatgt tagcgatgag
    17281 caggcagaga tttacaatac ggttctaaaa gctaaccaag ccttgattga ccaagctaag
    17341 gcaggcttag gtttccgtga ctttgacaaa atccctcgtg atattatcat tgaggcaggt
    17401 tatggcgact actttactca cggcattggc cacggtattg gtctggatat ccatgaggaa
    17461 ccctacttta gccagacttc tacagaaact attaagacag gtatggcctt gaccgatgaa
    17521 ccaggtatct atatcgaagg caaatatggc gttcgtatcg aggatgatat cctgattaca
    17581 gagacaggtt gtgaattatt gaccctagct ccaaaagagt tgatagtcat ttagttgttt
    17641 gtcaagaaaa aagtacgaaa atgacgaaaa aagtcaaaaa aaattaaaaa taggtcgcaa
    17701 gtcggatgtt ttttatggta taatagacta aactgatagt aacatgtagc gaaaggggta
    17761 ggtacatgat taaaatttat acagtctcaa gttgtactag ctgtaaaaaa gcaaaaacct
    17821 ggctcaatgc ccaccagtta agttataaag aacaaaacct tggtaaagaa ggaattacga
    17881 gagaagaatt actggatatt ctaaccaaaa cagataacgg aatagccagc atcgtttcgt
    17941 ctaaaaatcg ctatgccaaa gcccttggag tggatattga agatttgagt gtcaatgaag
    18001 ttctcaatct gattatggaa acaccgagaa ttttaaagag cccaatcctt gtagatgaaa
    18061 aacgcctgca agttggctac aaggaagacg atattcgtgc cttcctacca cgctctgtcc
    18121 gtaatgtaga aaatgcagaa gcacgtttac gtgcagctct ataaacatca aggctgggag
    18181 cacttcccag tcttattcta ttttaatttc aaaaagaaag aagagagaaa tgaaaaaaat
    18241 agttcttgtt agtctagctt tcctttttgt cctggttggt tgcggacaga aaaaagaaac
    18301 tggaacagct acaaaaacag aaaaggatac gcttcagtcg gcattgccag ttattgaaaa
    18361 tgccgagaag aatacagttg taaccaagac tttggtcttg cccaagtcag atgatggtag
    18421 ccagcaaact caaaccatta catacaagga caagactttt ttgagcttaa cgattcaaca
    18481 aaaacgtcca gtttctgatg agttgaagac ttatatcgac caacatggag tggaagaaac
    18541 tcaaaaagct cttcttgaag cggaggagaa ggataagtct atcattgaag ctcgtaaatt
    18601 ggcaggtttc aaacttgaaa caaaactatt gagcgcaacg gaacttcaaa caacgactag
    18661 ttttgatttt caagttctgg atgtcaagaa ggcttcccag ttggaacatc tgaagaatat
    18721 tggtttggaa aatcttttga aaaatgaacc aagcaaatat atttcagata gattggcaaa
    18781 tggcgcgaca gaacaataga aaatccaaat aaatagactg cctgaattgt agaaggtaag
    18841 gaattatgct ataatggtac tattctaagg aaagagggtg ttagaatggg atttactgaa
    18901 gaaacagtac gttttaaatt ggacgattcc aataaaaaag aaattagcga aactttgaca
    18961 gatgtttatg cttcgttgaa cgataagggt tacaacccaa ttaaccaaat cgtaggttac
    19021 gtattgagtg gagaccctgc ctacgttcct cgttataata atgcacgaaa tcaaatccgt
    19081 aagtatgagc gtgatgaaat cgttgaggaa ttggttcgtt actacctcaa aggacaagga
    19141 gtcgatctat aacctatgag aattatggga ttggacgtcg gttcaaaaac ggtaggggtg
    19201 gcgattagcg atccgcttgg ttttacagct caagggcttg aaatcatcca gataaatgaa
    19261 gaacaaggcc aatttggttt tgaccgcgtt aaggaattgg ttgatactta caaggtagaa
    19321 cgatttgtag tgggcttgcc taaaaacatg aacaatacaa gtggaccgcg cgtagaagct
    19381 agtcaagcct acggagcaaa gctagaagag ttttttggtt taccagtaga ctatcaggat
    19441 gaacgcttga caacagtggc tgctgagcgc atgttgattg aacaagcaga tatcagtcgc
    19501 aataagcgca agaaagtcat tgataagtta gcagctcagc tgattttaca aaattattta
    19561 gatagaaaat tttaatataa aggagaggct atgtcacacg atcataacca cgaccacgaa
    19621 gaacgtgaac taatcacact agtagatgag caaggaaatg aaaccttgtt tgaaatcctt
    19681 ttgacaattg atggaaaaga agaatttggt aaaaactatg ttcttctagt accagttaac
    19741 gcagaagaag acgaagacgg acaagttgaa atccaagctt actcattcat tgaaaatgaa
    19801 gatggaacag aaggcgaatt gcaaccaatc ccagaagact cagaagacga atggaacatg
    19861 attgaagaag tcttcaacag ctttatggag gagtgataca gtctgggaga ctgtatcagc
    19921 ccaactccca gaaatgggga agagttggaa cgtccagtga acatttttac cccaactctt
    19981 agaacttgag aagagttgga acatctagtg gatgttttta gcccatattc acattcatag
    20041 tagctagtta ttagctaacc aggtaagagg tcgggacgaa aatcctggcc ttgtttttat
    20101 tagtaaccat actttaatgc gataattgat tggacttttg tcaaggagat gtgtatgttt
    20161 gaagtagaag aatggctcca tagtcggatt ggtttgaatt ttcgatcagg tttgggccga
    20221 atgcagcaag cggtggattt gttaggaaat cctgagcagt cttaccctat tatccacgta
    20281 acagggacta atgggaaagg atctaccatt gcttttatga gggaattatt tatggggcat
    20341 ggcaaaaaag ttgcgacctt tacctcccct catatcgtct ctatcaatga ccgaatctgc
    20401 attaatgggc aacctatagc agacgcagac tttatccgtt tgactgatca ggtcaaagag
    20461 atggagaaaa cgcttctgca aactcctgcc cagttgtcct tttttgaatt gctgacctta
    20521 gttgcttttc tttattttag ggagcaggag gtggatttgg ttttattaga agtgggaatt
    20581 ggtggcttac ttgacacgac caatgtggta actggagagc ttgctgtcat cacctccatt
    20641 gggcttgacc atcaagaaac cttgggtgat agtctagaag caattgcaga gcagaaagct
    20701 ggtattttca aggatggtaa gaaggcagtg attgcgaaat tgcctccaga agctaggctt
    20761 gtctgtcaga aaaaagccga atctttagct gttaaccttt atcaggcagg tcaagatttt
    20821 ttaatgctga atggtgattt ttcaagctct ttactaaatc tttcacagct gaacataggc
    20881 ttagaaggag tctatcagca ggagaatgca gccttggcgt tgcaaacttt tcttcttttt
    20941 atgagagaag gaaaggaagc tgttgatgaa caggctgtaa gaaaggcctt ggaacagacc
    21001 cattgggctg gtcgcttgga gcgtattcgc ccacagattt acttggatgg tgctcataac
    21061 ctccctgcct tgactcgctt ggttgagttt atcaaagaaa aagagcagga aggctatcga
    21121 cctcaaatcc tctttggatc cttgaaacgg aaggattatc aagggatgtt gggttatctg
    21181 actgaaaatt tacctcaagt ggaactcaaa atgaccggct ttgactatca agggtctttg
    21241 gacgagacag atgtcacagg ttaccatgta attccctctt accgagaatt tatcagcagt
    21301 ttcgaagaaa gggcagacgc tcaagacttg ctgttcgtta cagggtctct ctattttatc
    21361 tcagaagtac ggggctacct gctggaccgt gagcagataa attgaccccc ttgtttgaac
    21421 ttgttatact aggggaattg ctggttagag aaaatttctc taaattggta gcagaaagga
    21481 aattcatcat gaaattaaaa agattcacac tttctcttgc ttctctagca agttttagtc
    21541 tcttagtagc ttgttcacaa agagctcaac aggttcaaca gcctgttgct cagcaggtcc
    21601 aacagcctgc tcaacagaat accaatactg caaatgcagg aggtaaccaa aatcaagcgg
    21661 ctccagtaca aaaccaacct gttgctcaac cgaccgatat tgatgggact tatactggtc
    21721 aggatgacgg agaccgtatc actttagtgg taactggaac gactggtaca tggactgagc
    21781 tcgaatctga cggggatcag aaagtcaaac aggttacatt tgattcagca aatcaacgca
    21841 tgattattgg cgatgatgtc aaaatttaca ctgtaaacgg taatcaaatc gtcgtagatg
    21901 atatggatag agacccatcg gaccaaatcg ttttaactaa ataagactat gcaagtagaa
    21961 agggctggat ttttcagcct ttttactttt acctagaaaa taatcataaa tacttgcctt
    22021 ctaccgaata cctgcgttat actagtatca attacttgtt tttagcattc aaactatcaa
    22081 ggaggggata tgaaatatag gaaatttcaa ttattgatgt ccaagtatgg ctttagtctt
    22141 tcgattatgc tacttgaact ttgtcttgtt tttggtctct ttctttattt aggacgcatg
    22201 gctcccattt tatggattac tgtcctcatt ctactgagta tcatcacaat catttcgata
    22261 gtcaaccgta atacgactcc tgagaataag gtaacctggt tgttagtagc ctttgtgcca
    22321 gtatttggtc ccttgctcta tctgatgttt ggtgaaaggc gattgtccaa aaaagaaatc
    22381 aaacaactga agaagctagg ctctatgcat ttccaagaag caaatagcca gctactaaaa
    22441 gagaaattaa aagaaagtga caaggcagct tatggagtca tcaagtcctt attgagtatg
    22501 gataccaatg ctgacatcta tgatcaaact gcctctacat tttttcctaa cggagaagct
    22561 atgtggaaaa agatggtaga agatcttaaa aaggctgaga aatttatttt cttggaatat
    22621 tacattatag aagaaggttt gatgtggaat cgcatactag atatactaga gcaaaaggta
    22681 gctcagggtg tagaggttaa gatgctctat gatgatatcg gctgtatggc tactttaaca
    22741 ggagattatg cacatcgact tcgtcagctg ggcatcgagg cccataaatt caataaagtt
    22801 attcctcgtt tgacagtggc ttataataac agagatcata gaaaaatatt gattgttgat
    22861 ggtcagatag cctatactgg tggggtcaat ctggcagatg agtacattaa ccacgtcgag
    22921 agatttggtt attggaagga tagtggaatt cgcttagacg gactagcagt aaaagccctg
    22981 acacgcttat ttttgaccac ttggtacatt aatcgaggag aaattagtga ttttgatcaa
    23041 tatcatttag aaaatcattc tatcccgagt gacggtttaa ccattccata cggaagtgga
    23101 cccaagccaa tttttcgagc gcaggtaggg aaaaaagttt atcagagttt aatcaatcaa
    23161 gcaacggaat cggtctatat tacgacacct tatttgatta tagattatga tttaacagag
    23221 acaatcaaaa atgcagctat gagaggggtc gatgttcgaa ttatcacccc ttacatacca
    23281 gataagaagt tcattcagtt agtcacgaga ggggcttatc ccgaccttct ttctgctggt
    23341 gttcggattt atgagtatag tccaggtttt attcatagta agcagatgtt ggtagacgaa
    23401 gattttgcgg tggtggggac aatcaatctc gactaccgga gcttggtaca ccattatgaa
    23461 aatgcagtct tactctataa aactccttct ataatggaaa tcgcccgaga ttttcgaaat
    23521 atatttgcag attctcagga agtctatcct cattctatca aaacgagctg gtatcaaaag
    23581 cttgtaaaag aaatcgccca gctattcgcc cctatcttat aagaaatcta gaacttagga
    23641 tacaaaccag acctattttt cttgtctttt acgaatagaa agaaagagga ggggaattca
    23701 tgctaactaa ggaagaagtg aatgatatga ttgagttcaa acagacacat ttacaccgct
    23761 ttcgggaaat tgaaaccttt gtgaaactat gcaaaaaatc actcaaacag ccatcgcaag
    23821 ctgacaatcc taggactttt tgatatacta agacagataa attgaacagg agaaacgata
    23881 tgagtgtgta tggtagagta gaagaagttc ataaggagaa tcgtgaacct ctagaatacc
    23941 aaatcgaaca agaatcgcat catcgtgaat caagtcgtct tcctttggtg aaaattttac
    24001 tatggagtac gcttgtaacg gggataactc taggagtacc gctattactc gacttaatga
    24061 gtgcacaaga agtgcaggat ttttatgcag gttgggcgct tcatcagaca gggaagattt
    24121 acagcgacta ttatggaagt caaggtttgc tttattattt gctgacttac gtgagtcagg
    24181 gcggatattt ctttgccatc tttgagtggt tagccttggt agcaggagga tttttccttt
    24241 ttagatcagc ggacaccttg acagagcaag gagaccaagc tggacatctg gtgactattt
    24301 tttacatgct agttacaggt cttgcttttg gtggaggcta tgcgactctt ttagcgcttc
    24361 ctttcttatt cgcagccttt agtttagttg cggcttacct aagcaatcca agccatgata
    24421 agggatttgt acggattggg ctagctttgg caggcggatt tttctttgct cccttatcat
    24481 cgctcctgtt tattgctgta gtgagtttag gcttgttggt ctttaacctt gggcatagac
    24541 gttttgtgca tgggttttat cagtttcttg cagtggcttt aggtttttca cttgtctttt
    24601 atccaactgc ctactatagt gctgcaacag gaagttttgg ggatgcgatt agtggtattc
    24661 gttatcctat tgacagtatt cgctttgatt ttacttctaa aattttagag aatatgtttt
    24721 tttatggctt gttgtccctt ggtttgggat ttgtggtttg tatcttttta ggtctctttc
    24781 aatccaaacc ctttaaacta tacgtcattt cggttcctgc aagtcttgtg gtaattttag
    24841 gtttgatttt acttttcttt tcacaagagc ctctgcacgc ttcttatttg atggtcgtct
    24901 tccctgtttt cctactttta ttggtaacca atattaagag tcaacagagg gggcgtagtg
    24961 ctagaagaag ccgaagagaa acgccagtta gcctatggag tcgtttcttc aaaggaaatc
    25021 tatatctgct agtttttggg tttgtctatc ttttgtctgt tccttttttg atgaagtttg
    25081 tcctttatcc agtaccttat caagaacgta atcgtcttgc tgatttggta aaagaggaga
    25141 caaatacgga agatgctatc tatgcatggg atgatactgc gactctttat cgtaagagtg
    25201 agcgcttgtc gccatcggcg attttgtacc cgttgcacta tacagcaact gaagaaaatc
    25261 gtaataagtt acttaatgac ttgaaagaaa aacaacctaa ggtgattgtg gtaaatgaca
    25321 aggtggtagt ctggtctgaa gtggaaacac tcttaaaaga aaattaccaa caagtaaaga
    25381 ctgattactc agagtttaaa gtctataaaa ttaaataacc aaatcaatat cttgtgtatt
    25441 tttaaaaatt ttaggatttt taacacaaga tattgatttt tctttttaga gtggtataat
    25501 actttttaga aagaacattt tagaaaagag catgcatatg attgcactag aagaaaaaat
    25561 tacaattttg ccaactctct tcgtcgagaa acgagatggg agacgtgttg tatttgatgt
    25621 ggacaagatt gacaaggctc tccacaaggc ggctgacaag gttatggatg tgacacccct
    25681 ggttgaaaaa cgcctcaatg atctgactga gcgaattatt acagaaattc atagtcgctt
    25741 tccacaggga attaagattt acgaaattca aaatatcgta gaacatgaac tccttgaagc
    25801 caaagaatat gcactggctg aggagtatat tacttatcgg acacagaggg attttgagcg
    25861 ctcaaaagcg acggatatca actttagtat tcataaactt ctcaacaaag accagacagt
    25921 tgtcaatgaa aatgctaata aagacagtga tgtctttaac actcagcgtg atttgacagc
    25981 agggattgtt gggaaatcaa tcggactgca aatgcttcct aagcacgtag ccaatgccca
    26041 ccaaaagggg gatatccact atcacgattt ggactacagt ccctataccc ctatgaccaa
    26101 ctgctgtttg attgatttta agggtatgtt ggaaaatggt tttaagattg gaaatgcaga
    26161 ggtagagagt cccaagtcta tccagactgc gacagcacag atttctcaaa tcattgccaa
    26221 cgttgcttct agccagtacg gtggctgttc agctgaccgt atcgatgaaa ttttggcgcc
    26281 ttatgcagag aagaactatc aaaaacatct caaagatgca gaagagtggg tattgcctga
    26341 aaaacgggaa gattacgctt ggaagaaaac gcaaaaggac atctacgatg ccatgcaatc
    26401 tcttgagtat gaaatcaata ctctcttcac ttcaaatgga caaacacctt ttacttcgct
    26461 aggttttggt ctgggaacca gtcgttttga acgagaaatt caaaaagcta ttttaaacat
    26521 tcgcatcaag ggtcttggtt cagaacaccg tacggctatc tttcctaaac ttattttcac
    26581 tctgaaaaga ggccttaatt tagaggaagg aactcccaac tacgacatca agcagttggc
    26641 tcttgagtgt gcaaccaaac ggatgtatcc agatgtttta tcttacgata agattgttga
    26701 cttgacagga tccttcaagg tgcctatggg ttgccgttct ttcctccaag gatggaagga
    26761 tgaaaatggt gtagaagtca attcaggtcg catgaatctg ggtgttgtga cggttaatct
    26821 gcctcgtatt gctcttgagt ctgaaggtga tatgaataag ttctgggaaa tcttcaacga
    26881 gcgaatgaat atcgcagaag atgctcttgt ttaccgtgtc gaacgcacta aagaggcgac
    26941 accagcgaat gctcctatcc tttatcagta cggtgctttt ggccatcgtc taggtaaaga
    27001 agaaagtgtt gaccagctct ttaagaatcg tcgtgcgacc gtttcgctgg gctatatcgg
    27061 cttgtatgaa gtagcgacag ttttctttgg taacagctgg gaaagtaatc cagatgctaa
    27121 ggaattcacg ctagacatca ttcacgatat gaaacgccgt gtagaagagt ggtcagacca
    27181 atatggctac catttctcta tctactcaac accatccgaa agtctgacag accgtttctg
    27241 tcgactagat atagacaagt ttggctctat tcctgatatc acagacaagg aatactacac
    27301 caactctttc cactacgatg ttcgtaaaaa tccaacaccg tttgaaaaat tggactttga
    27361 gaaagtctat ccagaagcag gtgcgtcagg tggtttcatc cattattgtg agtatccagt
    27421 ccttcagcaa aatccaaagg ccttggaagc tgtctgggat tatgcttatg accgtgtagg
    27481 ctatctaggc accaatactc cgattgaccg ttgctacaag tgtgactttg aaggggattt
    27541 tgaaccaact gagagagggt ttgcttgtcc aaactgtggc aatagcgacc ctaaaacagt
    27601 agatgtggtg aagcgaactt gtggctacct aggtaatcct caagcaagac cgatggtcaa
    27661 cgggcgtcac aaggaaatcg ctgcgcgtgt caaacatatg aatggttcaa cgattaaaat
    27721 agctgggcat caagtaacag attagaaaga aatgaaatgg gaaaatatca actagacgat
    27781 aaggggtgcg cacaagtgac ccgttatcac gagaaacact ctaaaggtgg agctggtaag
    27841 aaagaacgct tgcttagctt cagagaacaa tttttaaaca agaacaagaa aaaataaaag
    27901 tgagagccag ctctcgcttt tctcatagtg ggaggtaagg atggaattac gcagaccaag
    27961 attagcggat aagaaagctg ttttagatat gatgacagag tttgaaaaat ttcagtcgcc
    28021 tcacgacggc ggtttctggg atacagagaa ctttgtgtat gaagactggt tagaaagcaa
    28081 tcaggaacag gaaatgggga ttaatctgcc tgaaggatgg gttcctgcaa ttcagttagt
    28141 ggctttttct gagaaaggtc aagcagttgg atttcttaat ctccggttgc gcctcagtaa
    28201 ctttctacta gaagaaggtg gccacattgg ctactccatt cgtccatctg aaagaggcaa
    28261 gggttatgca aaagagactc tccgtcaggg cttgcaagtt gctaaggaaa agaacatcaa
    28321 gaaagctctg gtgacctgta gcgtgaataa tcctgctagc agagcagtca ttctagcaaa
    28381 tggtggaata tttgaggatg ctcgcaatgg agtcgagcgt tattggatag aggtagcgaa
    28441 tgaataatcc aaaaccacaa gaatggaaaa gcgaggaact tagtcaaggt cgtatcattg
    28501 actacaaggc ctttaacttt gtggacggcg aaggcgtgcg taactctctc tatgtatcag
    28561 gctgtatgtt tcactgcgag ggatgttata atgttgcgac ttggtctttt aatgctggca
    28621 ttccctatac agcagaatta gaagagcaga tcatggcaga tcttgctcag ccctatgttc
    28681 aaggtttgac tttgttggga ggggagcctt ttcttaatac tgggattctc ttgccacttg
    28741 ttaagcggat tcggaaggaa ttgccagaca aggacatctg gtcctggacc ggctacactt
    28801 gggaagaaat gatgttggaa actccagata aactggaatt cttgtcactg attgacattc
    28861 ttgtcgatgg aagatatgat cgaactaaga gaaatcttat gctccagttt cgaggttcat
    28921 ctaaccaacg aattatcgat gtgcaaaaat cgctcaaaag tgggcaagta gtgatttggg
    28981 acaagctcaa tgacggaaaa gaaagctatg aacaggtgaa gagagaatga agaaaaaatg
    29041 aagaaaaaag acttagtaga ccaactagtc tcagagatcg agacggggaa agtcaggaca
    29101 ctgggaatat acggtcatgg agcttcaggt aaatcaacct ttgcacagga attgtaccaa
    29161 gctttagatt ctactacagt aaaccccaat tattcacccc aaatctaaaa accatccaga
    29221 atccttgcct tagcttagat cctggatggt ttcttttttc acccaatggg tgttttttac
    29281 tagacaaaaa agagtttccc ctttatggta taagtgtaga aaaaaacaca aaaagaaagg
    29341 aaactcatat gaacagttta ccaaatcatc acttccaaaa caagtctttt taccaactat
    29401 ctttcgatgg aggtcattta a
//
LOCUS       DAVLZG010000023        24996 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLZG010000023 DAVLZG010000000
VERSION     DAVLZG010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.023"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..346)
                     /locus_tag="VYO72_000975"
     CDS             complement(<1..346)
                     /locus_tag="VYO72_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707372.1"
                     /translation="MGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVY
                     IFLGYVLVIQKDV"
     gene            complement(385..723)
                     /locus_tag="VYO72_000976"
     CDS             complement(385..723)
                     /locus_tag="VYO72_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1707373.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            1189..2052
                     /locus_tag="VYO72_000977"
     CDS             1189..2052
                     /locus_tag="VYO72_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707374.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(2238..2708)
                     /locus_tag="VYO72_000978"
     CDS             complement(2238..2708)
                     /locus_tag="VYO72_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV1707375.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(2674..3480)
                     /locus_tag="VYO72_000979"
     CDS             complement(2674..3480)
                     /locus_tag="VYO72_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1707376.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3687..4328)
                     /locus_tag="VYO72_000980"
     CDS             complement(3687..4328)
                     /locus_tag="VYO72_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707377.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4325..6433)
                     /locus_tag="VYO72_000981"
     CDS             complement(4325..6433)
                     /locus_tag="VYO72_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1707378.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6485..6781)
                     /locus_tag="VYO72_000982"
     CDS             complement(6485..6781)
                     /locus_tag="VYO72_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1707379.1"
                     /translation="MIGEINHEKISVASLMVCGILATTNALAVWVEGGQWNYGVGWTG
                     TFGYSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            7186..7506
                     /locus_tag="VYO72_000983"
     CDS             7186..7506
                     /locus_tag="VYO72_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1707380.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(7558..8145)
                     /locus_tag="VYO72_000984"
     CDS             complement(7558..8145)
                     /locus_tag="VYO72_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1707381.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQKLVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8387..9058
                     /gene="sdaAB"
                     /locus_tag="VYO72_000985"
     CDS             8387..9058
                     /gene="sdaAB"
                     /locus_tag="VYO72_000985"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1707382.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            9067..9939
                     /gene="sdaAA"
                     /locus_tag="VYO72_000986"
     CDS             9067..9939
                     /gene="sdaAA"
                     /locus_tag="VYO72_000986"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1707383.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9961..10593
                     /locus_tag="VYO72_000987"
     CDS             9961..10593
                     /locus_tag="VYO72_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1707384.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            10643..10900
                     /locus_tag="VYO72_000988"
     CDS             10643..10900
                     /locus_tag="VYO72_000988"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707385.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSNHIRQGDVDVI"
     gene            complement(10986..12836)
                     /locus_tag="VYO72_000989"
     CDS             complement(10986..12836)
                     /locus_tag="VYO72_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1707386.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(12878..14035)
                     /locus_tag="VYO72_000990"
     CDS             complement(12878..14035)
                     /locus_tag="VYO72_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1707387.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVINNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            14093..15259
                     /locus_tag="VYO72_000991"
     CDS             14093..15259
                     /locus_tag="VYO72_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1707388.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15398..15724
                     /locus_tag="VYO72_000992"
     CDS             15398..15724
                     /locus_tag="VYO72_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1707389.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            15711..16304
                     /locus_tag="VYO72_000993"
     CDS             15711..16304
                     /locus_tag="VYO72_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1707390.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            16297..17208
                     /locus_tag="VYO72_000994"
     CDS             16297..17208
                     /locus_tag="VYO72_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1707391.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            17271..18335
                     /locus_tag="VYO72_000995"
     CDS             17271..18335
                     /locus_tag="VYO72_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707392.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(18407..19267)
                     /locus_tag="VYO72_000996"
     CDS             complement(18407..19267)
                     /locus_tag="VYO72_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1707393.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(19389..20375)
                     /locus_tag="VYO72_000997"
     CDS             complement(19389..20375)
                     /locus_tag="VYO72_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1707394.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(20647..22122)
                     /locus_tag="VYO72_000998"
     CDS             complement(20647..22122)
                     /locus_tag="VYO72_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1707395.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(22206..23129)
                     /locus_tag="VYO72_000999"
     CDS             complement(22206..23129)
                     /locus_tag="VYO72_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1707396.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(23143..24072)
                     /locus_tag="VYO72_001000"
     CDS             complement(23143..24072)
                     /locus_tag="VYO72_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1707397.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(24391..24741)
                     /locus_tag="VYO72_001001"
     CDS             complement(24391..24741)
                     /locus_tag="VYO72_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707398.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         7589 a         5398 c         4465 g         7544 t
ORIGIN      
        1 atacgtcttt ttgtatcact aaaacataac ctaaaaatat atagaccatc aaatctagta
       61 caaaaagaga aaatatcctc cttttcatta ccttacttgc cttaaagatt ctgtttaata
      121 gaacctttat cgtagtatct acacaaattt ttatcaaaaa gataagagcc aatacacctg
      181 ctgctgcacc aataagccaa cctccaaggc ctccaacctt aatatagttt attagttttt
      241 ttgttaaaac tgcagctcca gtcaatgcta taaaagttcc tgggctcata gctaaagctg
      301 cgcaaattcc ttgacaagca ctcttgctta aataagcccc ccccatcaag atacatcatc
      361 tcctcttgct caagagcaac ataattattt ggtaatacga gttccattta ttttctcctt
      421 tatactatgt aataccacaa aatgattttg acctaaatca ttcttaactt gaagaatcgc
      481 aggaaatgtt aattttggag tcaaatcttc cagtgccact cgaacagctt ttactgtaaa
      541 attcaactta ttcagacctg aaacaatacc actgacagtc gttccataca tgtctgtacc
      601 aataatttcc cgaatcttca tgattgatag ttcctttttg taagataaaa gaactgttga
      661 aacaactgcc gcagcacaat ctgactgatc atgttgcatc gtacaaggat atttttttaa
      721 catagaaata ctcaattctt tagaattaat ctaacttttc tttgatgtca cccaaacctc
      781 aatcactgcc cagtagttct tgaatcagtt tattttcaat cgtatcattc tttgttcttg
      841 atatctttcc aagcattgta gtacagcaga tttttgtcca aggactgagc ctcctttaac
      901 aactcaagct cccttacatt atatcgacca gccccatgga aagattatga ccagactaat
      961 caatgatatc atacatacta gaatacaaaa tattttttta ttcatacttt ttctcctatc
     1021 tttattttct acctacatca tacctcttat taagctcatt ttaaaattac gttaactttt
     1081 ttcacaaatt tatttcgact ttctttttta ctttttacat tgctatgata caatattttt
     1141 aacaagattt tattatttgt taactttttt cacagaaagg agaaaatcat gcgttatgat
     1201 ttcggaaagg tctataaaga aatacgtgag tcaaaggggc tgacccaaga agaggtctgt
     1261 gggggtgttc tctcaagaac cagcttatca aaaatcgaaa gtggcaagac aaccccaaaa
     1321 tatgaaaata tggaatttct tctccgtcaa atcaatatga gttttgaaga gtttgaatat
     1381 atctgtcaac tttatcaacc aagtcaacgc acagagatta tgcaaaccta tctcaatatg
     1441 cgttccatta tcgggaccag cgatcttgtc aatttatttc aaaaatgcca agactacctc
     1501 aagacccacc acgatctccc tatagaagaa atcagagata tgcttgaagt tgtcatttat
     1561 atccgtcaac acggggcagg ggaactatca gatcacgcag aacaggttgt caaaaaactt
     1621 tggagaaaaa ttgaaaaaca agatacatgg tatgagagtg atctaaaaat cctcaatacc
     1681 attcttttca gttttcccat tgaatacctc catctcatca ctggaaaaat attgcaacgc
     1741 ctagaagtct ataaaaacta tcaacattta tatgacttgc gaatagcaat cctgctcaac
     1801 ctttccacac tctatctata caatcaagat aaaaacatgt gtaagcaaat ctgctacact
     1861 ttactggagg acgccaagaa taagaaaagc tacgataggc tggctatctg ctatgtccgc
     1921 attgggattt gtacagacga ttctaaactt atccaaaaag gtttctcact cctagagctg
     1981 accgaggaaa cttctatgct gtctcatctc aaaaaagaag tagagatcta ttaccaagcg
     2041 aaggaaagat aaaaaagccg agggagctcc tcgacctttt catagaatcg ccgaacgatt
     2101 taacgagaaa gtatgacttt tacgtttatc ccaactcaat tatgacattt ttttcaaaag
     2161 tcaatatatc tcactttttc aacgacaaga aagaggctga taatctacca acctcttatt
     2221 ctgaacccat cactccatca ctttttagct tcattcgctt tcttagcgac tgcaatctgg
     2281 tattcgactt ggtcattccc cttaccggta caaccatgag caattgtagt cgctcctatc
     2341 tgatgcgcta tttcaaccaa ttttttagaa atcagagggc ggctcaaggc agataccaag
     2401 ggatactttt gttcataata ggcatgtgac tgaagagcca ctagcacata atctgtagca
     2461 aattcgtcct taacatcaat gacataagat tctactgccc caaccttaag agccttatca
     2521 tggatgaaat ctaagtcttt cccttcaccc acatccatac aaactgaaac aacatcatag
     2581 tctttcttta accaggtaat agcaactgat gtgtccaaac cgccagaata ggccaaaatt
     2641 actttttctt tactcatgtt cttttccttc tttctatttt tcaatggatg ctttaaaggc
     2701 atcctcaatg agtttgtcta attccccaga ctccttcaac ttttgaatgg ttttatcgac
     2761 tgcctctttc aattccttgc tatctttttt catggctacc gcgtaggaat catcttgctc
     2821 tttttcaaaa ttgaggtctg cgattgctaa atcaggatta ttttccacaa atcccttgga
     2881 aacaggttct tcaaagataa cggcatccac ttgtcctgat tttaaatctg tgattaaatt
     2941 cccattttta ggcagagata cgagggaaga attttgtagc aaatctttcg ccatcgtctc
     3001 ttgaatcgaa cctttctgcg ctccaacctt tttctgcgcc aagtcgttta cagactgata
     3061 agtagtcaag tcagattttt tgacaatgag tttatttttt gcagtatagt agggaatgga
     3121 aaagtcaaac accttgctcc gttcatctgt cttagaaaca cctgatatgg caaggtcggc
     3181 ttttcctgat tgaacactag ccagtacatt atcaaaactc atgggagata gttccaattc
     3241 gacacctagt tctgttgcga tagccttggc taattcgata tctgaaccca caatctgatt
     3301 tttcccatca accacttttt ggtattcaaa tggagcaaaa tccggattga gggctacaac
     3361 caattttcct ttggacttga tggcttcaat tccagccgat tgattgttgc tacaagcaaa
     3421 tagtaggggg agcatcacta aaccaaacat cgtcatcaac accttcttca tcttattcat
     3481 aataaagcct actttatgtt tattcctttt gtttgtataa acaatacatc tatattcatc
     3541 ctttgtcaag cctaaattga aaaaattttc aatttgaaac aaaaaaaacc tagaaatact
     3601 acataaaatg tcattcctag gcgtatttat gctatttttc tctggaaaac atgagtattc
     3661 agccagtcaa aaggagctga atgaactcat tttccctcgc ccaattcaat gacacgatga
     3721 cattgttggg ctacataagc atcgtgggtc acaataatga ctgttttccc ttctcgattc
     3781 atctctaaga gaaacttcaa gaccaaatct ctattttcag gatccagcga acctgtaggt
     3841 tcatcggcta aaatcagctg gctgggtttt aagatggctc tagcaactgc aattcgttgt
     3901 tgttcgccac cagacaactc ggagaccctt tgatgcaaag tagctgacaa acctactctc
     3961 tctaaaatct cttccacctt tttgagcttg tctttcttag gcaatttcac atatttcagc
     4021 gccagcatga gattgtactc gaccgtttca tcatcaatca gggcaaaatt ttgaaacaga
     4081 taagagatat gttcacggat tattgtttgc gacttagcag aattaaccgc tagatttgtc
     4141 tgaccaaaaa tctcataccg tccgctataa tcaccatcta tcaaacccaa taaatttaac
     4201 aaggtcgact tcccactacc actcttacca acaatagcta ccaaatcccc ctgatcaatc
     4261 ctgagagata agttatccaa aatcactttt cccccaatgg ttttggtaat atttttcaac
     4321 tcaatcataa gatgccccct ttcaataact ctactagact tcttttctcc atcctagaag
     4381 ctaagcctag cacaaatagt atatccagac atgtaaaacc tgcaaacagt agaagtggta
     4441 agaacgcatg ggcaaagaaa atcaagacta gaagagggaa actatagccc agcaagagca
     4501 gaacgaggag aggacggtag cgatcgacca gtttccaccc cataaacttc ttggtaatga
     4561 tatccctgcg cttcaataag aaagttgtta ctagtaagaa gtaggaaatc atcatgctaa
     4621 ggagaccaaa caaagcaaag agtaggttaa aattccgaac agcatctcta taagaatcca
     4681 ctttctcttg ttgaatggct tgaatagatg aaaattttaa ataatttcca tctgacaatt
     4741 tctcaactaa ctctgtaatc tctttttgat gttgaaccgt attttcaatt ttaatcggat
     4801 tatttaagcc agttgttgac agggaggctt tctcatccca catcatatca gaatcattga
     4861 ccaagctaat aattggattg gagagatttt cctttcgctt atcactatat gggaaaaatg
     4921 accaatctcc ttcataatag gcaatctcga catccatctc ctctatcgtt cgtttttgct
     4981 gctcttcata cttcatcgaa tgaaaggcaa ttaacttccc caagagctga tttttatctt
     5041 cttcaccttt cgtacttgct ggcatcaaaa taactttttt aataccggta tctggtagct
     5101 tgaatccctt gctctttaga aaattgcgat tggcatagta aacatccacc gtatctgtta
     5161 actgatattg ctgaatctgt tctgattgga caaaattttt tacaggaaga ctgctactct
     5221 gcacatagcc cgcctgcgtt ttttctacca aatcctgata aaatcgatag aaataatctg
     5281 tagatttccc tgaccctgct agctcttctt gccacagatt atcattgagt ttgaaggttt
     5341 ctaaggtcag gtaattacct tgacttaccc actgttgctg ataagcaagt tctttgtttt
     5401 cttgttctaa acttctgccc accccaatca gtaaggccgt cagtaaaata gttgtcccta
     5461 ttttcatcac ataattgaag ataagaccaa atttgaaaga tgaaaaacct ttcagcagag
     5521 agctgattgt cattttttgg attaagaggt aagtcaacca actgataaag agataaagct
     5581 gcaacagcaa aaaatgagac aaccacagca taggaaacaa atcttttggc ttataatcaa
     5641 gcaagaaaaa cacgcctaga ttgatcacaa gagccccacc taggaggagg taaaggttgc
     5701 cttttacaac atcagctaaa acagccctat cttgaaaacc aagtaatttt tgtaccccaa
     5761 ctcttttcat ctccatcatc ggttgataca ctgtcactaa cacaagaagc aaaatagcca
     5821 agacaaaaac aatggcagat aaaagcaaat ctcgatttat gacttccact gcacttttgt
     5881 aggtcggctc tagcaaggta gcctggtcta tcttgaaaaa atcgctccat ttctgtacaa
     5941 tcctatcctt gtccatctct tgtgtagaag ttatcgtata gcgaccattt aaactacgag
     6001 atgtatcctt gatataggtt tgaaaagtca taagctgaat aggtttggct tttagaaagg
     6061 tcggaatcgt accaagttta ttggaaattt ctttattact atagactcct tcaccatctg
     6121 tggtaaaatc aagagaagaa atcccaaact cttggtaggg gaaggtatct ttatcaaaaa
     6181 caccagactt gaccacctca tcaccactgt ctgttttgat gatggagact ttatactcct
     6241 ttgatacatc ctcaaaaaat cgaagaacag acgctgcagg ttcgttaata tctttcaaat
     6301 acaaatccaa agaatctaca gtctttccca tttcttgaat ccgaaccact tctcgtgtat
     6361 agtttacatt aaaaacaaaa aaagtggtac acagaagcag gagtaacata cagaaattac
     6421 tgattttttt cataaaagtg cctccactac agttttccct ctccaaatag gagagggaag
     6481 aattttactc aaatccatag aaatattcca ttcctgttgg cggaatcttg gtgagggaag
     6541 ctctagccca tgcctcaggt tttgcataat ccttagaggt tctaccccca tgtctaacag
     6601 ttgctgtatg atatcgagta gaatgtaagt aatcagaata tccaaaagtt cctgtccaac
     6661 ctactccata gttccattga ccaccctcaa cccatactgc taaagcattt gtagtagcaa
     6721 gtataccaca taccattaaa gatgcaacac taattttctc atgatttatt tctcctatta
     6781 tcgagagctg ttccgtaaaa acagctatag taatttatca acaagtatcg tagtccattg
     6841 gactcacctt ccttctatct catttcattt ttaacaacga acttactctt aaccgggaga
     6901 atggtgcgct tctgtatcag gtccttgaac aaccagagta gtattaagca cactctaact
     6961 attactcaag aatcagtcca ataaacaata tggatagcgc tttcaaattt ttaaactcct
     7021 atcccatcct tttatctata taataagtga aaatataata actgtcaagt aactgaagtg
     7081 aattttataa aaaaattaca agccaaattt gtaaagttta cactaagccg ctagggcaat
     7141 cgtctatcag aatatccgtt tatttgtcaa taatccgaga aaatcttgca acgcttagaa
     7201 gtctataaaa actatcaaca tttatatgac ttgcgaatag caatcctgct aaacctttcc
     7261 acactctatc tatacaatca agataaaaac atgtgtaagc aaatctgcta cactttactg
     7321 gaggacgcca agaataagaa aagctacgat aggctggcta tctgctatgt ccctattggg
     7381 atttgtaggg atgatgcgaa acttatccaa aaaggtttct cactcctaga gctaaccgag
     7441 gaaacttcta tgctgtctca tctcaaaaaa gaagtagaga tctattacca agcgaaggaa
     7501 agataaaaaa gccgagggat ttcctcgact ctttacatat tatttgttcg ttagttctta
     7561 ataccagcca ttgttaagcc agaagttttt agcagctgtc catgaaccgt aacgtcctgc
     7621 aacgtaggca tctgctacac gttcttggtt ttcagctgag tagtcaccgt tcaggtatga
     7681 atctgttaat tggtaacgtc cgatataacg tccatttgta gctgtatagc taccacctga
     7741 ttctttttga gcgatccatt ctttggcttc tgcttcagat ccgcttacag ttgaaacaac
     7801 tgtttcactt actactggag tttctgccac tggagctgaa acagtttcat cttgagcggc
     7861 tggtgccgca taagtagctg gcgctggtgt tgcaacaggc gctacagggc catcgataac
     7921 caacttttga tcaacataaa tcaaatgaat gttatcaatg tggttgtttt ctgccaattt
     7981 ttcaactgtt gtgttgtgag tttcagcgat ttctgaaagt gtatcacctt ctttaacagt
     8041 gtaagttgat gattcttgag cagatacaaa tgatggagca aatactgcaa acaaggcagc
     8101 tactcctgca agagttgctt taatcttttt agttattgat ttcatattcg aaaattctcc
     8161 ttctttctat agttctatca taccctttaa atattaccgt ttcttgacac ttttatgtag
     8221 aaatattaca aaattatttt ttatttccct aaataaggtg ttttttgtca taaaagatac
     8281 tatttttatg ctatttgagg tattagaaag gttttcatcc acaattaaag ccaagcccct
     8341 cattctttga tataatagag ataagaattt ttataagggg aaactgatga aatcacttcg
     8401 ttttcaatct gtctttgata tcatcggacc agttatgatt ggcccatcta gtagccatac
     8461 cgctggtgct gttcgtattg ggaagattgt ctcttccatt tttgatgata ctccgacaga
     8521 agttgaattc caacttttta actcatttgc caagacctat cgtggtcacg gaacagacct
     8581 agcccttgtt gcaggtattt taggaatgga tacagatgat cctgaaattc caaatagtct
     8641 ggaaattgcc cacaagcgtg gtatcaagat tgtctggacc attcagaaag acagcaatgc
     8701 ccctcaccct aacaccacta aaattactgt taaaaatgcc cacaagacca tcagcgtgac
     8761 tggtatttct atcggtggag gaaatattca ggtaaccgaa ctcaatggtt ttgccgtctc
     8821 tctcaatatg aatacaccga ctatcatcat cgttcatcaa gatattccag gtatgattgc
     8881 ccttgttaca gaggcgcttt cccgctatgg tatcaatatc gcccagatga atgtcactcg
     8941 tgaaaaagct ggtgaaaaag ccattatgat tatcgaagtt gacagtcgca actgtgatga
     9001 ggctatcgaa gaaattcgaa aaatccctca tctccacaat gtcaatttct ttaaatagga
     9061 ggaagcatgt tttattctat caaagaattg gtcgagcaag cagatctgga ctttcaagga
     9121 aatgtcgcag aactcatgat tacaacagag tttgaattga ccggtcgcga acgtgaagaa
     9181 gtcttccttc tcatggaacg caatctggaa gttatgaaag cctctgtcca acttggcctc
     9241 aatgaaaata aatctcgtag tggcctgaca ggtggagatg ctgccaaatt ggatcactac
     9301 atcgaaaacg gaaaaactct gtcagattat acgattctct cggctgcccg aaatgccatc
     9361 gcagtcaatg aacacaatgc caaaatgggc ttggtctgtg ccactccaac cgctggaagt
     9421 gctggctgtc tgccatccgt tctcactgct gctattgaaa aattagacct cagccacgag
     9481 caacaattgg atttcctctt tgctgctggt gcctttggac tagtcatcgc aaacaatgcc
     9541 tccatctcag gtgctgaggg tgggtgtcaa gctgaagttg gttcagcctc tgctatgagt
     9601 gctgccgcct tgactctggc tgcaggtgga acaccttatc aggccagtca agctattgcc
     9661 tttgtcatta aaaatatgct aggcctcatc tgtgaccctg ttgcaggttt ggtcgaagtt
     9721 ccctgtgtca aacgtaatgc catgggagct agctttgctt tcatcgcagc agacatggcc
     9781 ttggcaggta tcgaatctaa aatccctgtg gatgaagtga tcgatgccat gtaccaagta
     9841 ggagcaagca tgccaactgc ctttcgtgaa acagctgaag gtggactcgc taccacccct
     9901 actggtcgtc gcctccaaaa agagattttc ggagaataag cttatcaaat aggagaaacc
     9961 atgacctcta tcacagcgat ttttttcgat ttggatggaa ccctcgttga tagttctatc
    10021 gggattcaca atgcctttac ctataccttt aaagagctgg gggtgcctag ccctgatgcc
    10081 aaaactattc gtggttttat gggaccacct ctcgaaagta gttttgcgac ctgcctgtcc
    10141 aaagaccaaa tttctgaagc catgcagata tatcgttctt actataaggc aaaaggcatc
    10201 tatgaagctc aactctttcc tcagattata gacttgcttg aggagttatc gagcagttat
    10261 ccactctaca tcaccacgac aaagaataca tctactgctc aagacatggc caaaaacttg
    10321 gaaatccatc atttctttga tggtatttat ggttctagcc ctgaagcacc ccataaggca
    10381 gatgtcattc accaagcctt acagacacat caactagcac cagaacaagc catcatcatc
    10441 ggagatacca agtttgatat gctgggagct cgagaaacag gtattcagaa attggccgtc
    10501 acttggggat ttggagagca agcagatcta ctaaactatc aacctgatta tatcgctcac
    10561 aaacccttag aagttttggc gtattttcaa tagcatagac tgggtaacaa ctccatttca
    10621 gaagaaaatg aagtaatact caatgaaaat caaagagcaa actaggaaac tagctgcggg
    10681 ctgctcaaaa cactgtttta agattgtaga tggaactgac gaagtcagct caaaacactg
    10741 ttttaaggtt gtggatggaa ctgacgaagt cagctcaaaa cactgttttg aggttgcaga
    10801 tagaactgac gaagtcagct caaaacactg ttttaaggtt gtagatggaa ctgacgaagt
    10861 cagtaaccat atacggcaag gcgacgttga cgtgatttga agagattttc gaagagtata
    10921 agtctctaca taataaaacg catattacca aggttgttta acttgataat atgcgttttt
    10981 cttttttatt caatgtgggt tgtttgatta gcaaaggcga taatagcttg cttcaactca
    11041 tctccactga gagtgcggaa ctctccaatc ttttgattga tggattctaa aggcatgaca
    11101 ttaaccttac caacgaaaat cttatccata acttgattgt caacgagttc ggttgatacc
    11161 aagagttctt cgtagagttt ttcacctggg cggattccaa cttcaacgat tggaatttca
    11221 ctctcagtgt ggccacttag aagcaccatc ttcttggcca agtcataaat cttgactggt
    11281 ttgcccatat caaggataaa gacttcccca tctttggcat aagcaccagc atggataacc
    11341 agacgactag cttctggaat ggtcataaag taacgggtca tgcggaagtc tgtcaccgtt
    11401 acaggcccac cttcagcaat ctgacgttca aagactggaa tgacactacc acggctacca
    11461 agaacattcc caaaacgaac tgcacagtag gttgattggc tacgttggtt aaagccagtg
    11521 acaatcaact ccgccacgcg cttggttgct cccataacat ttggtggatt aactgcctta
    11581 tctgtcgaaa tcataaccat cttaggcacc ttggcttcat caacggctct agcaacattg
    11641 taagttccac ggatattgtt tttgaaggct tcttttggat tgcgctccat cataggaaca
    11701 tgcttgtggg ctgccgcatg ataaacaata gcaggtttgt actgctcaaa gacttgcaac
    11761 aaacgatcat agtcttgaat gtccgcaatc acaggtacat aatcaatccc ttggaactta
    11821 cgaatcaatt catgataaac aaggtagatt gagttttccc catgaccgag caagacaatg
    11881 cgttcaggat tgaagcgact aacttgacga cagatttcag aaccgattga acctccagct
    11941 cctgtgacta agatggtctt acctgtcagt tctgcaccca gacgcgattc gtcaagacgg
    12001 atttcctgac gacccaaaag gtccgtaata tcaatttttt ggaagccagt acctgcttgg
    12061 tgaaggccct gaacaacagt ttcaacctta ggcatcttgt aacatttgac acccagctta
    12121 ttacacatct gcaagatacg ctcatattct gacggatcca gcgacggaat cgcaacgatg
    12181 acacgctcga tttgatggcg tttggctaat tcaggcagat tgtcataaga gcccaaaaca
    12241 ggaataccac caagtttttg accctttttc ttagaatcct tatccaaaat accgaccagt
    12301 tctaattcac tggttggatg ttggtaacta tccataaaga gagccccacc atcaccggca
    12361 ccaatcaaga aggtccgacg gtgttctcca tcaccactac cttttttgcg tctggagtag
    12421 attaactgcc aagtaatccg tggcaataaa atcaagaagg tactcaacaa gataaagaga
    12481 atgatgaaac ggatggagaa gagtggcaag aaggcataac agatactata tgacaagaca
    12541 ctgctagcag tcacaccaaa aaagattttc atgaaatccg taatcttgct gtaacgacta
    12601 atgctcgcgt tcaaccccca aaaaccaatc atcaattgat agaacaagaa ggccaaactc
    12661 gtatagataa tgtagtcaac aggtgctgga ttaatcagcc cataaaataa aatataagat
    12721 acaattatgg aaaccaccat actgaaaata tcaaatattc cccagaaaac ctgcttttgt
    12781 tgtttattta aaatttccac cagatcaatc acataatctg ttagtttttt attcatagaa
    12841 atctactcct ccttaaaaga gttttactat attgttatta tagcatattt tgatttattt
    12901 ggcttatttt atccaaataa attattgttc ccttgtactc cttcttccat ttaaatcctc
    12961 taattaaacc tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat aaaagaaagg
    13021 gcatcacaat tagaaatcca tttttatgtt ttaataaagt cagcaaagtg agtaatgaca
    13081 aaagtagaaa ataggcacct aatagtaaag ttatgaatac gaatgtgatc ggtaacaatg
    13141 ctagactaaa cacaagactc aaaacaaata aacaaggaac atagtgaaat aatgataaac
    13201 acttaaactg aacatgactt gtcaagccaa tccacaaacc atttgaatac ttttgatgca
    13261 gcattttctt gaatgttggt cgaatatact gataagatag aatacttggg ctatagcgga
    13321 ttttataacc atgttctcga attctataat gaatatcatt atcttcagtt cggccaagtt
    13381 gctcatttac taaaccaacc ttctggaaaa cctctcgttt atacatccca tgaaaaatag
    13441 aagaaacata tctatcctcg gaactatttc gataattggc aatgctactg ccaaacatat
    13501 tttcctcaac aagatgcaag gtctctgccc attttccttt tccttcgaca atcgtcggtc
    13561 taggcccccc acagacaaat tcaccttgtt gaataatagc cacattgtta attacaaaac
    13621 tctcagtaac ttttgaatga gcatcaattt ttaaaataag gtcccctaca gaatgtttaa
    13681 ctcccaggtt aaaaccacta gcttgatttt tcttaggatt gttatacaat ctaattgagt
    13741 taaactctgt atcttccttt ataaattgct gaatgatagc tgtggtccca tctgtggaca
    13801 tagcatttat aaatagaatt tcaatatcct ctttaggata ggtttgattt tttaagtctt
    13861 caattagacc aggcagatat ttttcttcat tgtatgcact gattacaatg gatacgagaa
    13921 gactttcaac attttgagtc actactactc tcctgaattt ttccttccac cattctatca
    13981 taattttcaa gactttccca tttttatctt gaaagccaga aaccttactt gacattatag
    14041 tgaaaaagcc ttaaaataag ctgttattaa aatcagctag aagaggtatt atatgaaaaa
    14101 gcaatcactc ttttttgttc caggtattat cctgattggt gtttccttgc gaactccttt
    14161 tactgtttta cccattattt tgggaaatat ttcgcaaggt ctggaggtag aagttagttc
    14221 gcttggtgtc ttgaccagcc tgcctctcct tatgtttacc ctcttttcac cattttctac
    14281 ccaactggct cagaaaatcg gcttggagca tctcttcacc tacagcctct tcttcttgac
    14341 catcggctca cttattcgac taatcaatct gcccctgctc tatctaggaa ccttgatggt
    14401 tggggcaagt gtcgcagtca tcaatgtcct gcttcctagt cttatccaag ccaatcaacc
    14461 aaagaaaatt ggttttctga ccaccttata tgtaacgtct atggggattg caacggctct
    14521 ggcttcctat ctagctgtgc ccattacaca agccagttct tggaaaggac ttatccttct
    14581 cctcacgtta ctctgtctag caactttttt ggtctggctc ccaaatcacc gctataatca
    14641 tagactagct ccacaaacca aacaaaaaag tcaaataaag gtcatgcgta ataaacaggt
    14701 ttgggcaatt attatctttt caggttttca atccttgatc ttttacaccg tcatgacctg
    14761 gttacctacc atgtctatcc atgcaggtct atccagtcac gaagctggct tgctgacttc
    14821 tatcttatct ctgattagca ttcctttttc aatgaccatc ccaagcctga caaccagttt
    14881 atctactcgc aaccgtcagc tcatgctcac tctggtttca ctagctggtg tggtcggcat
    14941 ttccatgctc tttttcccaa tcaataattt catttactgg cttgccatcc atctcctcat
    15001 cggaaccgca accagtgccc tcttccctta tctcatggtc aacttttcac tcaagacaag
    15061 cgcccctgaa aagacagccc aattgtccgg cctatctcaa acaggaggct atatcctagc
    15121 agcctttggg ccaaccctct ttggttacag ttttgacctg ttccactctt gggtaccatc
    15181 tgtagctgcc ctcttgctca tcgatatcct gatgactgtg gccctcttta cagtggacag
    15241 agcggataag atcctttaaa cttctagttt tagctagaag ttttttatat ataaaaattt
    15301 tacacatttc tcttgacagg gctttctttt agatgtacaa tgtatgtgta gaaaaattat
    15361 atataaaaat cttacacatt agaaaaggag gtttcccatg tactttccaa catcctctgc
    15421 cttgattgaa tttctcatct tggctgtact ggagcagggt gattcttatg gttatgagat
    15481 tagccaaacc attaagctga tcgctaatat caaagaatcc acactctatc ccattctcaa
    15541 aaaattggaa ggcaatagct ttctgacaac ctattctaga gagttccaag gtcgcatgcg
    15601 caaatactac tccttgacaa acggtggtat agagcagctc ttgaccctaa aagatgaatg
    15661 ggcactctat acagacacca tcaatggcat catagaaggg agtatccgcc atgacaagaa
    15721 ctgaatacct gactcagcta gaactctatc tcaagaaact acctgaagct gaccgtatcg
    15781 aagccatgga ctatttcaga gagctctttg acgatgctgg agtcgaagga gaagaagaac
    15841 tcatcgctag tttgggaact cccaaagaag cggcccacga agttctatcc aatcttctcg
    15901 ataaaaaaat caatgaagca cccgctcaaa aaaataaccg acaaatttta catatcgcct
    15961 tgttagccct ccttgcagca cctatcggca ttcctctggg aatcgccatc ctcgtgaccc
    16021 tgttcgcaat tcttgtagcc gctttgactg tcattctggc tttctttgca gtttccatac
    16081 tgggtatcat cggcggattc ctatttttag ttgaaagttt cactgtcctc gcccaagcca
    16141 aatcagcctt tatcttgatt tttggttctg gtttactggc tatcggtgct tcttcgctag
    16201 ttttacttgg catttcctat gcaactcgct tcttcggtct actcattgtt cgtctggtac
    16261 aatttgttct taaaaaagga aagagaggta atcagcatgc gtaaatggac aaaaggattt
    16321 ctcatctttg gtgtggtgac taccgttatc ggctttatcc tgctttttgt aggtatccaa
    16381 tctgacggga ttaagagcct actttccatg tccaaagaac ctgtctatga tagccgtacg
    16441 gaaaagctaa cctttggcaa ggaagtcgaa aacctagaaa ttactctcca ccaacacacg
    16501 ctcaccatca cagactcttt cgatgatcaa atccacattt cttaccatcc atctctttct
    16561 gctcaccatg atcttatcac caatcagaac gatagaactc tgagtctcac tgataagaaa
    16621 ctgtctgaaa ctccgtttct ctcttctgga attggtggga ttcttcatat cgcaagtagc
    16681 tactctagtc gttttgaaga agttattctc cgactaccaa aagggagaac tctaaaaggg
    16741 atcaacatct cagccaatcg cggacaaacc accatcataa atgctagcct tgaaaatgcg
    16801 accctcaata caaacagcta tatcctccga attgaaggaa gtcgtatcaa aaacagtaaa
    16861 ctcacaacgc ccaatatcgt taatatcttt gatacagttc ttacagatag tcagctagag
    16921 tcaacagaga atcacttcca cgctgaaaat atccaagtcc atggcaaggt tgaactgact
    16981 gccaaagatt atctcagaat catcctagac cagaaagaaa gccaacgaat taactgggac
    17041 atctcaagca actatggttc tatcttccaa ttcacaagag aaaagcctga atcaagaggt
    17101 acggaattaa gcaaccctta caaaactgaa aaaaccgatg tcaaggatca actcattgcg
    17161 agatctgatg ataatattga tctaatatcc acaccaagca gacgttgaca aaaacgctta
    17221 catttgctac tatggaaaca tatttatcta actaaaaagg aggttctacc atgaaacaag
    17281 aatggtttga aagtaatgat tttgtaaaaa caacaagcaa gaacaagcct gaagagcaag
    17341 ctcaagaggt tgcagacaag gctgaagaaa cgatagccaa tctcgataca ccaattggaa
    17401 aaaatactca agtagaggag gaagtctctc aagctgaagt cgaactggaa agccagcaag
    17461 aagagaaaat tgaaactcct gaaggcggtg aagcgagaac agaaatagaa gaaaagaagg
    17521 catctaattc tactgaagaa gagccagacc tttctaaaga aacagaaaaa gtcactatag
    17581 ctgaagagag ccaagaagct cttcctcagc aaaaagcaac cacgaaagag ccacttctta
    17641 tcagtaaatc tttaaaaagt ccttatatcc ccgaccaagc tccaaaatct agggataaat
    17701 ggaaagagca agtgcttgat ttttggtctt ggctagtaga agcgatcaaa tctcctacaa
    17761 gtaagttgga aacaagtatc acacacagtt acacagcctt tctcttgctc attctgtttt
    17821 ctgcatcttc ctttttcttt agtatctatc acatcaaaca tgcttactat ggacatatag
    17881 caagcattaa cagtcgcttc cctgagcagc tagctccttt aactcttttt tctatcatct
    17941 ctatcctagt agcgacaaca ctcttcttct tttcattcct cttgggtagt ttcgttgtga
    18001 gacgatttat ccaccaggaa aaggactgga cgctagacaa ggttctccaa caatatagtc
    18061 aactcttggc aattccaatc ttcctcactg ctattgctag tttctttgct ttctttgata
    18121 gcctacgatt tacagctctc ttgtgtgtga ttagcattgg aatcattctg cttgccagtc
    18181 tccatatcat tacaagacca agtcaagcaa gtgaaaccga ctccttctat caattattct
    18241 tgtctgtcct tgtgaacgga gttattatcc tcctcttctt tgtagctgaa gtggcactga
    18301 ttggagatta tcttcgtatc ttggcctttc tttaaaattc aatcctgtca tccttggcag
    18361 gattttttct atgtcaaaaa agcaagtcga ttgacctgct tctgctttac ttttcttgtg
    18421 ctaatgtttt aaaatctttg tctaatatgg gttgcacttc tatttgattg gcgtctagtt
    18481 ggtggtaaaa agatgggggt aatacctcta agaattttgc atagtccaag cgagctatgg
    18541 attcatagtc ttctggttta gagccgtctc ctgtgatttg aaccaagtca atctcccact
    18601 ggacttcctt atccaccaat tgctcaatat aggctgcagg aacaaacggt tctctcggta
    18661 aaactgtctt gactccttga gctaaatggt aaacgccatg cacttttcct tctccatcct
    18721 gatagaagga aactcttgca aagtaggcat ctgtctcttg aaccgcacgc acacgcgctt
    18781 caaactgagc caagccatct gcctctaaaa agcttttcaa gttctcacga ctaaagaaaa
    18841 taggattaaa aattccttgg caaatcgtaa aacgagctac agggtctgct agataggctt
    18901 gaatacttgc ttggaaataa gcttcaaaat caaaaccatc tagcccttca atatcagtcc
    18961 ctgtataagc aagcaaagca tctaaaaatg acttgataat ctgccagtct gtctttgtta
    19021 gtaggtcagg aagatcgaca cggtaagcct tttgaccatc agcataactg accttaaaga
    19081 gaaattgtga ttgccccact atcgcacact caatatactc gagacgatta agaggctgac
    19141 gaagatagac tacatcatag ctatgtgact ccaaaccgtc tagcaaggcc aagatcgact
    19201 tggcattcaa aatctcttgt tctcctaaaa tgctctgttt atttggaata aaaaatgttt
    19261 ttgccataac tggactcctt tgaaatcgtt tacatacagt ataccttatt ttcctgaaag
    19321 atacaaaaac aaactttaga tttttgagta caaagcatag aaaaacagcc cctgaggact
    19381 gtttgatctt atacagtagc tgcctgatcc aagctttcac cgatagcggc taggcgctca
    19441 atcacttcag cttgtgtcaa ttcatttttt gaaacatagc ggttacgtgg gtgaacacgg
    19501 cactcgtgtg agcatccacg aaggtacttg tcttcatttt cttctgatgt caagatacga
    19561 cggttacaga agggatttcc acagttgaca taacgttcac atggtgttcc atcaaaccag
    19621 tctttcccta cgatggttgg gttgacatgg ttgacatcaa cggcaatacg ctcgtcaaag
    19681 acgtacattt tcccatccca aagctcacct tgaacttctg ggtctttacc gtaagttgcg
    19741 attcctccgt gcaattggcc gacatctttg tagccttcac ggaccatcca gcctgagaat
    19801 ttctcacagc gaacgccacc tgtacagtaa accacgacac gcttgtccat gaatttttcc
    19861 ttgttatcac ggacccattg tggtaactca cggaagttgc gaatatctgg gcgaatagcc
    19921 ccacggaaat gtcctaggtc gtactcataa tcgttacgtg tgtcaaggac aacggtatct
    19981 ttatcaagaa gcgcttcttt gaactctttt ggagacaagt aagcacctgt tgtttcaagt
    20041 gggttgatgt cattgtcaaa gtcgttgtct tccaaaccaa ggtggacaat ttctttcttg
    20101 tagcgaacaa acatcttctt gaaggcttgt tcattttctt cgtcaatctt gaaccagagt
    20161 tcttccattc ctggaaggct gtgaacgtag tccatgtatt tttgagttgt ttcatagtca
    20221 cctgaaactg ttccgttaat tccctcgtca gcgactagga tacggccttt aaggccgatt
    20281 gatttacaga aagccaagtg gtctgcagca aattgctctg cattttcaat tggagtataa
    20341 aggtagtaaa gtaagacacg aatatctttt gccataagat ttgttctctt ttctattctt
    20401 aaattttcta aattttttat ttatctacac tagtatacct gcttgagaaa acgaatgcaa
    20461 tttatttgac tggaaattgt agagggttct cgaaatttcc tgaatggtta aaataaggac
    20521 aagagaaaac atggatatct atatccttgt gccaaaaaaa ccactgccct ccccagacca
    20581 acctgaggaa agcggtgatt cttattttag gagttaggaa tgaatacacg aaatcaattt
    20641 agctgattat tttttgtttt tcaagaattc atcgtattgt ttttgcattt cgttcaatac
    20701 tttttcgtag gcaccttcag atttcaattt ttccatcaat tctggaatcg ctttatctgg
    20761 gtctacagta ccagtgttga tagctgtatc aaattgttgc attgtgttag caatagctga
    20821 gatttcagat ttcacattgt cagtattgaa gataaatcca agcgctggag attctttagc
    20881 ttctgccaat tctttcttag aattttcgat ttgttggtct gtaacgtttt cgttgatgta
    20941 aaggatccag ttgttaccag tgttccatcc acccatgtga gtgtttcctt tgtagccatc
    21001 aagaacgcga acacggtttt ctttaccttc aattttttcc cagttcttgc cttctggacc
    21061 gtaaacaaga ccgttcaaaa gttctgggtt cgtattcaag aggttcaaga tttccattga
    21121 tttttctttg ttcttagagt tgtttgagat gacaaagtta gcaacttgtg ttgtttggtt
    21181 tttcttgatg aagttagtga ttggtttgat ttggatatct ttgttggcaa cacgtgaaag
    21241 caagctgtta ccgtagtcag ctggtcctac tgtttcttca cgaacgaacc aagtatcttg
    21301 ttgaaggtca aatgaagtgt cacttgttgc gacgtctttt ggaatgtagc cagcttcata
    21361 gaatttgtga agagtcttca agtgttcttt gaaacgaggc acttcgtaac ggtttacaac
    21421 tttagtagta tcgccttcaa ggtcaataac gaatggaagc ccgtttgcta ctgggtagtc
    21481 aaagttatca gatgggatga aaactttacc aatagcaaat ggtactacgt ctggagcttt
    21541 ttctttgatt tgtttcaaga ctggctcaag agtttcgtaa gaagtaacac ctgaaatatc
    21601 gataccatat ttggcaagga gagttccgtt gaaggcaaag ttttgagatg atgctacgtt
    21661 ggctgcaact ggtacagcgt aaatcttacc atttacagta ttacccttga tataagctgg
    21721 atcaagtgcc ttgtaaaggt ctttaccttc ttttttgtac aattctgtca agtcagcata
    21781 agcacctttt tgagcattta caatatagtt atctgcaaag gcgatatcat agttttcacc
    21841 agatgatgtg ataactgaca ttttcttacc atagtcaccc cagccaaggt attggatatc
    21901 caatttggca ccaacttttt cttcgatgat tttgttggca tttgctaaca attcatccaa
    21961 gttatctggt ttgtcaccga tttggtacat tttgataaca ggtttgtcac ctgaatcagc
    22021 agcttttttg ctgttacctg tcaaatttcc acaagcagca agacctgcag ccaaagcgac
    22081 tacactagca gatgcaaaag catatttttt ccagtttttc atgataaaaa ctcctttttt
    22141 tatttttaaa cttataaaca atgtaatgat cttaacttca cgcaagggaa gtttggaaac
    22201 aagtgctatt ctttcacacc accgatagtc aaacctttta caaagtagcg ttggaagaat
    22261 ggatacaaaa ttgcgattgg aagggttgct accacaacca tggccatacg acctgtttct
    22321 ttcggtagag caactcccag ttgaccagtc aagccgaccg ctttggcaat gtagtccata
    22381 ttttgttgga tttgcatgag caaatattgc aatggataca agttgtcact cttgatgtaa
    22441 agaagggcgt tgaaccagtc attccagaaa ccaagagctg tcaaaagcgt gatggttgcg
    22501 atacctggta gtgacaatgg caaacagatt tggaagaaaa tccgggcctc actggcacca
    22561 tcgatacgag ccgattcgag aatggcttct ggaatggtct tcttgaagaa ggaacgcatc
    22621 aagatgatat tgaatggtga gagaagcatt ggaacaatca aggcccaaac agtgtcacca
    22681 agctgaagta cacgggtcac catgatataa cctggtacca aaccagcgtt gaacaacata
    22741 ctgagaagga cgaagatggt aaaaaatctg cgatacttaa aggttgtccg tgaaatagcg
    22801 taggcatagg ttgttgtgat aaagacattt gtcaatgtcc caactacggt tacaaagaca
    22861 gagatgaaga gggcttgtag gattttatcc ttaaactgtg ccaaaaactc aaaaccgtct
    22921 aagccaaatt gggatgggaa gaagctatag ccgtattgga ggaggctttt ctcgtctgtc
    22981 actgaaataa tgataacgaa tacaaaaggt aggatacaag agagggcaat caaacccgaa
    23041 atgatactga agaagatatc tgctttctta ctgaaggagt gaatgccgac attatcaatt
    23101 ttttcttttt taattttctt ttttgccata ttctcctcct ttctagaaca aagctgagtt
    23161 tggatcgact cgtcttgcaa gcaagtttga taggataacc agaatcaaac caacaacgga
    23221 ttggtaaaga ccggctgctg cagccatacc gatatctgct gtctgagtca aaccattaaa
    23281 aacatatacg tccaaaacgt tggttacatt gtaaagctga ccagcattgt gtgggatttg
    23341 atagaagaga ccgaagtctg cgcggaagat atttccgact gcaaggatgg tcaatacagt
    23401 tacaagcgga gtcaactgag gaatggttac gttgcgaata cgttgccact tgctagctcc
    23461 gtccactgtc gctgcttcgt agtaggttgg atcaattccc atgatcgtcg catagtacat
    23521 gacactgcta tatccaaaac ctttccaaat acctaggaaa agtaggagat agggccagat
    23581 gcccaggtca gcgtagaaat tgacttcttt gagaccaaga ctttccaata gatgattgaa
    23641 caccccttta tcaatattta ggaaggcatc tgtaaagaaa ctgatgataa cccaagacaa
    23701 aaagtaaggg aacaacatag aagtttggaa aatcttcacc attctcttag aacggagctc
    23761 gctgaggata atggcaatcc ctacagatac aactaaacct agaaagataa agccaagatt
    23821 gtagaggaca gtatttcgtg tgataataaa ggcgtctctt gaactaaata agaatctgaa
    23881 attatcgagt ccgacccatt tactatttat gatactatct atgaaaccat tactggtcat
    23941 gtggtagtct ttgaaggcaa ccacgttccc aaatactgga atgtaaaaga atagaatcaa
    24001 ccagagtgcc cctggcaaaa ccatcaagag aaagatccag ttgtctctca atgtttttga
    24061 aaactttttc ataatttcct ccctttttat tttgatatcc atctaaaaat tcttttttag
    24121 acttttgata acgattacat tattagtata ctcctatttg caggttaggt taaactccta
    24181 attatagaaa aaattccaca aattatgtag cagatttaaa actttatcac cactatcaaa
    24241 caaatgtcct aaatcaattg tttattttat ctctattagc ccagtgatgg cgtcactctg
    24301 ttataagcat ccaacaacgg ggtatactga aaaatctcca gactagggaa ctcagcgata
    24361 gttcctaatc tggagatttt taatatgtta ttaggcgttt gctttcaact tagcaataac
    24421 ctctttaaga ttatcaatca actctgcttc agtatgctca gagccttttt catctgccaa
    24481 gaacaaaact gctttttgaa gttcttcttg agagttttca aggacatcct tatctgctgt
    24541 ttctttgccc gctgtttgtc ctccatcctt agttgctgac tggctttcct taatggactc
    24601 tagggaagca atggcatctt tgactgtttg caagatatca cgtaaacctt gctctgtcaa
    24661 actatcatct gtaagagctt tcttagcctc tgccaaaacc agacgtgctg aatctgtggt
    24721 aggattcgat acacctgtca atgatctcaa aagattttct aaggtttgag tctgcttact
    24781 aatactagac taaaatcaaa aagcattaca taacagtgat atgaaatcaa ctaaagaaga
    24841 aatccaaacc atcaaaacac ttttaaaaga ctctcgtaca gctaaatatc ataaacgcct
    24901 tcaaatcgtt ctatagtaaa atgaaacaag aacaggacaa atcgatcagg acagtcaaat
    24961 cgatttctaa caatgtttta gaagtagagg tgtact
//
LOCUS       DAVLZG010000024        23671 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLZG010000024 DAVLZG010000000
VERSION     DAVLZG010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.024"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(14..3190)
                     /gene="carB"
                     /locus_tag="VYO72_001002"
     CDS             complement(14..3190)
                     /gene="carB"
                     /locus_tag="VYO72_001002"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1707399.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3503..4582)
                     /gene="carA"
                     /locus_tag="VYO72_001003"
     CDS             complement(3503..4582)
                     /gene="carA"
                     /locus_tag="VYO72_001003"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1707400.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4632..5555)
                     /locus_tag="VYO72_001004"
     CDS             complement(4632..5555)
                     /locus_tag="VYO72_001004"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1707401.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5574..6095)
                     /gene="pyrR"
                     /locus_tag="VYO72_001005"
     CDS             complement(5574..6095)
                     /gene="pyrR"
                     /locus_tag="VYO72_001005"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1707402.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6306..6935)
                     /gene="nth"
                     /locus_tag="VYO72_001006"
     CDS             complement(6306..6935)
                     /gene="nth"
                     /locus_tag="VYO72_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1707403.1"
                     /translation="MVLSKKRARKVLEEIITLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(6935..7477)
                     /locus_tag="VYO72_001007"
     CDS             complement(6935..7477)
                     /locus_tag="VYO72_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1707404.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7647..7964
                     /locus_tag="VYO72_001008"
     CDS             7647..7964
                     /locus_tag="VYO72_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1707405.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            8203..9762
                     /locus_tag="VYO72_001009"
     CDS             8203..9762
                     /locus_tag="VYO72_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1707406.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9806..10705)
                     /gene="htpX"
                     /locus_tag="VYO72_001010"
     CDS             complement(9806..10705)
                     /gene="htpX"
                     /locus_tag="VYO72_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1707407.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10707..11267)
                     /locus_tag="VYO72_001011"
     CDS             complement(10707..11267)
                     /locus_tag="VYO72_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1707408.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11361..12074
                     /gene="rsmG"
                     /locus_tag="VYO72_001012"
     CDS             11361..12074
                     /gene="rsmG"
                     /locus_tag="VYO72_001012"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1707409.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12328..13610
                     /locus_tag="VYO72_001013"
                     /pseudo
     CDS             12328..13610
                     /locus_tag="VYO72_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
     gene            complement(13805..15376)
                     /gene="ffh"
                     /locus_tag="VYO72_001014"
     CDS             complement(13805..15376)
                     /gene="ffh"
                     /locus_tag="VYO72_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1707410.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15388..15720)
                     /locus_tag="VYO72_001015"
     CDS             complement(15388..15720)
                     /locus_tag="VYO72_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1707411.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(15811..16188)
                     /locus_tag="VYO72_001016"
     CDS             complement(15811..16188)
                     /locus_tag="VYO72_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1707412.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16260..17564
                     /locus_tag="VYO72_001017"
     CDS             16260..17564
                     /locus_tag="VYO72_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1707413.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17577..18383
                     /gene="yidA"
                     /locus_tag="VYO72_001018"
     CDS             17577..18383
                     /gene="yidA"
                     /locus_tag="VYO72_001018"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1707414.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(18438..18509)
                     /locus_tag="VYO72_001019"
     tRNA            complement(18438..18509)
                     /locus_tag="VYO72_001019"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18474..18476),aa:Arg,seq:cct)
     gene            complement(18551..18898)
                     /gene="rplS"
                     /locus_tag="VYO72_001020"
     CDS             complement(18551..18898)
                     /gene="rplS"
                     /locus_tag="VYO72_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1707415.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19017..19346)
                     /gene="crcB"
                     /locus_tag="VYO72_001021"
     CDS             complement(19017..19346)
                     /gene="crcB"
                     /locus_tag="VYO72_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1707416.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(19340..19714)
                     /gene="crcB"
                     /locus_tag="VYO72_001022"
     CDS             complement(19340..19714)
                     /gene="crcB"
                     /locus_tag="VYO72_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1707417.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19711..19977)
                     /locus_tag="VYO72_001023"
     CDS             complement(19711..19977)
                     /locus_tag="VYO72_001023"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1707418.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20093..20536)
                     /locus_tag="VYO72_001024"
     CDS             complement(20093..20536)
                     /locus_tag="VYO72_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1707419.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            20640..21575
                     /locus_tag="VYO72_001025"
     CDS             20640..21575
                     /locus_tag="VYO72_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1707420.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21629..21913
                     /locus_tag="VYO72_001026"
     CDS             21629..21913
                     /locus_tag="VYO72_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1707421.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(21970..22548)
                     /locus_tag="VYO72_001027"
     CDS             complement(21970..22548)
                     /locus_tag="VYO72_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV1707422.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(22523..23536)
                     /locus_tag="VYO72_001028"
                     /pseudo
     CDS             complement(22523..23536)
                     /locus_tag="VYO72_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(23539..23671)
                     /locus_tag="VYO72_001029"
                     /pseudo
     CDS             complement(23539..23671)
                     /locus_tag="VYO72_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         6943 a         5341 c         4531 g         6856 t
ORIGIN      
        1 cttatttttc tatttaaatc gcttctgtaa caaagctacg actttcaagt accttaagca
       61 tggcattagc tgtatctagc gctgtgaaga ggggcacccc gtgttcaatg gctgaacgac
      121 gaatttgctc accatcttcg tcagcagttc gttttgttcc tactgtgtta atgatagctt
      181 gaattcttcc tttgcgtaca aaacttggga tatccttatc gtcatcacca atcttaccaa
      241 caggttgggc ttgcaagcca tggctagcaa agaaggctgc tgtcccttct gtcgcaagga
      301 ttccataacc aatgttttgg aaacgacgag ccaagttcaa ggcttcttct ttggcatcat
      361 cagcgatggt aaagacgaca ttaccaaaag ttggcaagtg tagataagaa gcttcaaagg
      421 ctttatagag agctttttcc aaagtagcat cagaacccat aacttcacct gttgacttca
      481 tttcaggacc gagcaagctg tctaccttag ctagtttggt aaaggagaag acaggtgcct
      541 tgatatgaac acgggtgctt tcagggtaaa gtccattttg gtagccaagt tctgataaac
      601 tttgaccaag aatgagcttg gtcgctactt gagccatagg aatattggtt accttagata
      661 ggaatggaac agtacggctg gcacgtggat tgacctcaat aacgtagact ttttcatcct
      721 tgataacaaa ctggatgttc atcattccaa ggcagtgaag accgattgct aagcgtttgg
      781 tgtagtctgc gatggtctcc tgaacctttt gcgacaaggt ttgtggtggg taaacagcca
      841 ttgagtcacc tgagtggaca ccagcacgtt cgatatgctc catgatacca ggaatgagta
      901 catctttacc atctgaaatg gcatcaactt cgcactcttg cccaacgata taagagtcga
      961 caagaactgg gtgatctgga ctagccttaa cagcagttcg catgtaagaa cgaaggtctt
     1021 cttcgttttc aacgatttcc atggcacgtc caccaagtac ataagatggg cggacaagaa
     1081 ctgggaagcc aatcttacga gctgcaagag ctgcttcttc ttcattggta gccgtttgtc
     1141 ctggtggctg tggaatatcc aattctttga gagcttgctc gaagaggtca cggtcttcgg
     1201 cacggtctag gtcagcaacc tgtgtaccaa ggatggtcac acctgctttt gccaatggct
     1261 ccgcaaggtt gatggctgtt tgaccaccga actgaacgat aactcccttt ggttgttcca
     1321 agtcaatgac gttcataaca tcttcgaatg tcaatggctc aaagtaaagc ttatctgata
     1381 cagagaagtc tgttgaaacg gtctctgggt ttgagttcat gatgatagct tcataaccag
     1441 ctgcctggat agccttaaca gagtgaacgg ttgcgtagtc aaactcaacc ccttgaccga
     1501 tacggattgg acctgaacct aggacaagta cagattcttt atcagatctg atagattcat
     1561 tttcccaacc ataggttgaa tagaaatatg gcgtttcgga gtcgaactct gccgcacaag
     1621 tgtctaccat cttataaact ggaacaatct tgttttccaa gcgaagttgg cgaactttat
     1681 catcagtcgt tccccagagt tcagcaatct tacggtctga aaaaccatta agtttggctg
     1741 ttttcaaaac ttctagatct tgtggatgag cacccaattc ttgctcaatt tcaaagatat
     1801 gcaagagttt atcaagatag aagatatcaa tttttgtaag ctctgcaatt tcttcaggtg
     1861 tgtagccacg acgaattgct tctgatacgt agaagagacg gtcatcttgg gctttgacaa
     1921 ccttttcaat caaggcatca tcagaaactg ctgcaagttc aggtatttca ttgtggtgca
     1981 ccccaatttc aagggagcgg caggccttga gaagagattc ctcgatgtta cgaccgattg
     2041 ccatgacttc tccagtcgcc ttcatttgtg taccgagacg gcgttcaccc ttttcaaact
     2101 tgtcaaatgg gaaacgtgga atcttagcaa ctacgtagtc aagggctggt tcaaacatgg
     2161 cataggttga acctgtaact gggtttataa cctcatccaa ggtcaaacct actgcaatct
     2221 tggcagccaa cttagcaatc ggatatcctg tcgctttaga agcaagggct gacgaacgtg
     2281 atacacgagg gtttacttcg ataacataat acttgaagct gttaggatca agagctagct
     2341 gaacattaca tccaccttca atcttgaggg cacgaataat gctcaagctc gcatcacgaa
     2401 gcatttggtt ttcatagtct gacatggttt gcgcaggggc aaatacaatg gaatcccctg
     2461 tgtgaatccc aactgggtca aagttttcca tgttacaaac aaccaaggca ttgtcagctg
     2521 agtcacgcat cacttcgtat tcaatttcct tgaaaccggc aatcgaacgc tcaatcaaac
     2581 attgggtaac aggtgacaat ttcaaaccat tttcagtgat ttcacgcaat tctttctcgt
     2641 tggcacacat accaccacca gtaccaccaa gggtaaaggc tggacgaacg atgactgggt
     2701 agccaattgt cgctgcaaag gcaactgctt cttctactgt gttaacaatt tcagattctg
     2761 gaatgggttg ttcaagctct tccatcaatt gtttaaagag gtcacggtcc tccgcttggt
     2821 caatggcaga taatttggta cccagaagtt caacgccaag ctcgtctagg ataccatttt
     2881 tagataattc catggccatg ttgagacctg tctgaccacc gagtgttggt agcaaggcat
     2941 ctggacgttc cttacgaaga atacgtgtca caaactcaag tgtaatcggt tcaatgtaaa
     3001 ccttgtcagc aatttccttg tccgtcatga tggttgcagg atttgagtta accaaaacaa
     3061 cctcataacc ttcctctttc aacgacaagc aagcctgagt cccagcgtag tcaaactcag
     3121 cagcctggcc aataataatc ggaccagaac caatcaccat aattttttga atatcagtac
     3181 gtttaggcat atataagata ttaagggcgt caagcggaca aagctaaaat aggagttatg
     3241 acgaagaact gtcagttcta ggaataacta tctttttagc accgtccgta gcccgtattc
     3301 agttcagcaa atacggagca cccttctcct ttctattcgt cgcctctcag ggcgacatta
     3361 aataagatac aaaggacgaa tagaaagcga ttgaatttta gaaaatcaag gaaggattga
     3421 caatccaagt tgatttctct acattctgag ctttccgtcc gtgttcagtt acataaattc
     3481 tccgacgagc ttttactcgt tcttagtttg attgtttaaa aacttccatc atctcgataa
     3541 actcgtcaaa taggtagcta gcgtcgtgtg gcccaggagc tgcatctggg tggtattgaa
     3601 cagagaaagc aggttggtat ctgtggcgca caccttccac tgacttgtca ttgatttctt
     3661 cgtgggtaat aatcaagtgc tctggcaaat cctcgcggct gactgcataa ccatggttct
     3721 ggctggtgaa gtctactcgt cctgttgcga tttcacgtac cgcatggttg aatccacggt
     3781 ggccaaactt catcttatag gtcttagccc cgtttgccat tgcaaagagt tggtgtccca
     3841 tacaaatacc aaagattgga atttttcctt gtacaccgcg aatcatgtcg agtgcttgtg
     3901 gaacgtcttc tgggttacct ggaccatttg acaacataac cccatcagga ttgagatgga
     3961 gaatttcttc agccgttgtc gaataaggaa caactgtcac gttacagttg cgtttagaaa
     4021 gttcacgtag gattgagtgc ttgagaccaa agtccactag caccacgctc aaaccaactc
     4081 ctggagctgg ataagacgtt ttagtagaaa cctgtttgat attgtctgtc ggtaaaactg
     4141 ttgcttggag ctggtccgtc acatggtcca tactgtcccc aacatgggtc aaggttgcac
     4201 gcatagtacc atgcttacgg ataatcttgg taagagcacg cgtatcaatt cctgaaatcc
     4261 ctggaatttt tttggctttc aaaaattcat ccaaggtcat ttggttgcgc cagttgctag
     4321 ctctacgcgc ttcttcaaaa acaacgactc ccttacaagt tggaataatg gattcataat
     4381 catcacgatt aataccataa tttcctacca aaggataagt aaaggtcaag atttgtccat
     4441 tataagactg gtctgtaatg gattcttggt agccggtcat ccctgtatta aagacgattt
     4501 cgcctgttac atcaatatct gctccgaagg ccttgccttc aaaaactgtg ccatcttcta
     4561 atactagaat tctttttgtc atattttcac ctctcgtgga cgctcactgg cgtcttttaa
     4621 cgtcttgtgt tttagttggc gtttctactc gctagtacgg attctaagat tgccattcga
     4681 acaaagacac cattggtcat ttgttggaca atccgtgatt ttggtgcttc aaccaagtgg
     4741 tctgctattt ctacatcacg attgattgga gctgggtgca tgaggattgc tgtttctttc
     4801 aaacgatcgt aacgttcttg agtcaagcca tgttgggcat ggtagtcttc ttttgaaaat
     4861 acagctccac tatcatggcg ttcgtgttgc acacggagaa acatcatgac atcaacctga
     4921 tcaatgattt catcaatggt tacaaactgt ccatagtctg caaactcttg acttctccat
     4981 tcctcaggtc cagcgaaaaa gagttcagct cccaagcgtt tcaaaatctg catattggat
     5041 ttggcaacgc gtgagtgatc caagtcacct gcaatagcaa ctttaagacc ctcaaagtgg
     5101 ccaaattcct cataaatggt catcaaatca agcaagctct ggctagggtg ttggcccgaa
     5161 ccatctccac cattgatgat ggaagtcgta atcgttggac tagcaatcaa ttctctatag
     5221 tagtcgacct ctggatggcg aatcacacag acatccactc ctaaagcaga cagagtcaaa
     5281 atggtgtcat aaagtgtctc acccttatta accgaactag tcttcacatc aaagtcaagt
     5341 cgttccaatc caagtttaat ctctgcgact tcaaaggact tatgtgtccg tgtagaatcc
     5401 tcaaagaaga gattggaaac aatcggatgg tcttcatagg gaagctgggc tccattttta
     5461 aactcaattc ctcgcttgat caatttcatt acttgatcga cagtgaggtc ttccatggac
     5521 accacatggt tcaatgcttg ttgattttct gacatggcta ctcctttaac tttctaagct
     5581 tcttcagtaa tcagaactct gtcttggtca tcaagttctg tcatctctac gatgatttct
     5641 tcagaacgac tggttgggat attttttcca acgtaatctg gacggattgg caattctcta
     5701 tgtccacgat cgactagaac tgctaaactc acacgcgcag gacgaccatg accgacaata
     5761 ttatcaatag cagcacggat ggtacgacct gtatagagca catcatccac caagataact
     5821 tcgcggtctg tcacatcgac agaaaccaaa gaagtatctt ctccactttt aacatcatca
     5881 cggaaaggtt tagtatccaa ttccacaaca ggaactgaaa gattttctaa ctgcttcaaa
     5941 cgttcttgga ttcggtgggc aataaagaca ccacgagttt taataccagc caagacgatc
     6001 ttattcaaat ctttgttgcg ttcgataatc tcataagtaa tacgcgtaat cgctcgtttg
     6061 acggtcaatt cgtctacaac ttcttttgtt ttcatgacaa acctccaaaa agaaaagtct
     6121 ccttaaacaa ggagacttga aatttatagc caagcgagcc ctactgcaca cagtatagac
     6181 ttcacccttc tactttatcg cgctccttgc ctgcctcacg ggacaggttt aaaggaatat
     6241 ttagttatca tttactatag cacaaagcat gcttaaaatc aagcaaaaag tttcaatgta
     6301 gcatcttaca aattgctaaa atcatataat tgtgggtact ggtcacactc tggatttttt
     6361 ggatggcaaa tggctcttcc aaaataaatc atggcctgat gggcagctaa ccactgctca
     6421 ggcggcaaga tatccatgac ccgcttttcc acctcaagtg gcgtcgctga ttttttgaca
     6481 atatcgtggt gtttgcaaat acgctccaca tgagtatcca ctgcaaaggc tggaatccca
     6541 aatcctacac tcatgacaac attggctgtc ttgcgaccaa cacctgccaa actctccaat
     6601 tcttcacgtg tctgagggac ttgaccatca aaatcgtcta gtaactgttg ggcacatttt
     6661 ttaaggaatt tagctttatt ccgatacaat cccaagcgag aaatatgtga agcaatctca
     6721 ctctctgtcg ctacagacat agcttggggt gttggaaagg caacaaagag acctggtgtg
     6781 gccttattta ccgctgcatc tgtcgtctgg gctgataaca tgaccgcaac caggagttca
     6841 aaatgattgg taaaatcaag actaggcttg gcatctggga agagggtaat gatttcttct
     6901 agcacctttc gtgctcgttt ttttgacaag accattattc atctccgtca aatagtcctt
     6961 gtaagccagc aaaaggactg ttttcttctt tctttactgc tttttgagct tggtattctt
     7021 cctctgtcat gatttgccag tcatttcctg agataaatcc ttgaccagct tcttcttcag
     7081 ccgtcaagac cttgatagga atgtttagca ggatattgtc tgatacactc tcagcaaggt
     7141 caagctcccc attttcgatg ggcaagacca agtcatcatc taaaacttct tgatctagct
     7201 ggttagttgc gccttccatg aaaacttccg tgactggata agattcaact aactcaactg
     7261 gctccatact gcgactcgaa gcaagaacaa tggtataaga tagttgataa tctaagaaat
     7321 acatacggtc ttcatattgt actttcccaa ctgcaaggat atcttttaca tctaaaattt
     7381 cttgattacg tgcacgcagg tcatcaacta aatctaacgt ttgttcaaag ttcaaacctt
     7441 cagactgctt acgaatttct tgaatattta atttcatact tcctccataa agatttactc
     7501 tcttgattat accatgaaaa ggctacaaat cagcacacca aactttgtaa ttaaaattca
     7561 aaattttaac atatttacta ttatagtttt attttttagt gctatactat agggaaagag
     7621 tacatcagat caaggaggat gctcacatgg aagacaagaa actcattcaa ctcctatcca
     7681 agttaaataa aagctaccaa aactgtaaac agggtacggc agatgatatt cgactacaag
     7741 agctgctaaa cactactatg caagagctca aaaaaacgga acagttgaac aacagtatct
     7801 taattgatct tgagaaattt taccaaccta ccagtcttct gattggactg ggtagcctaa
     7861 aactaaacga tcaagcacgc actgcttggc gaaactatga taaattccat tacgagcatg
     7921 tcaaacacgt actaagtctc tatggacctg tttttgaatt ttagagcata gaatttccag
     7981 ttttctgttg acaaaatttc cttaaaggta taatataaag atactaatac tcggaggtaa
     8041 gggagacatg aacaactaag tctatcaaat aaagaacctt tatttagtag atcttgtttt
     8101 tgtctctttt tgtgtgctct tttatgctct ttttctggca tgttaataga gtttttttga
     8161 catagacttt gggctctact aggtaaagta gagctttttg ttatgcacta tgaacattct
     8221 agaaagggaa atcatatgat aaaaatcaat catctaacca tcacacaaaa caaagattta
     8281 cgagatcttg tatctgacct aaccatgacc atccaagacg gggaaaaggt tgctattatt
     8341 ggtgaagaag gaaatggcaa atcaacctta cttaaaattt taatggggga agctttgtct
     8401 gatttcacta tcaagggaaa catccaatct gactatcagt cactggccta cattcctcaa
     8461 aaacttcccg aggagctgaa aaagaaaact ttacacgact acttcttttt agattctatt
     8521 gatttagact acagtatcct ctatcgtttg gcggaggaat tgcattttga tagcaatcgt
     8581 ttcgcaagtg accaagagat tggcaatcta tcagggggag aagctttgaa aattcagctt
     8641 atccatgagt tagccaaacc ctttgagatt ctatttttag atgaaccttc aaatgaccta
     8701 gaccttgaga cagttgattg gctaaaaggc cagattcaaa agaccaggca aaccgttatt
     8761 ttcatttccc atgatgaaga ctttctttct gaaacggcag acactattgt tcacttgcga
     8821 ctggtcaaac accgtaaaga agcggaaacg ctagtagagc atttagacta tgatagctat
     8881 agtgagcaga gaaaggctaa ttttgccaaa caaagtcagc aagctgctaa caaccaaaga
     8941 gcctacgata aaaccatgga aaaacatcgg agagttaagc aaaatgtaga aactgcgctt
     9001 cgagctacca aagatagtac tgccggtcgc ctattgtcta aaaagatgaa aactgtcctc
     9061 tcacaagaaa aacgctacga aaaggcagct cagtccatga ctcaaaaacc acttgaagag
     9121 gaacaaatcc aacttttctt ttcagacatc caaccattac cagcttctaa agtcttagtc
     9181 caactggaaa aagaaaattt gtccattgac gaccgagttt tggttcaaaa actacaacta
     9241 actgtccgtg ggcaagaaaa aatcggtatt atcgggccaa atggtgttgg gaaatcaact
     9301 ctgttagcca aattaaagca acttctgaat gataaaagag agatttccct tggttttatg
     9361 ccacaagatt accacaaaaa actacaattg gatttatcac caatagctta tatcagcaaa
     9421 actggggaaa aagaggaact tcagaaaatc cactctcacc tagccagtct caatttcagt
     9481 tatccagaaa tgcagcatca aattcgctcc ttatctggcg gacaacaggg aaaactcctg
     9541 cttttggatc tagtcctgcg caaaccaaac tttctcctgc tggatgaacc cacacgaaac
     9601 ttttctccca cttctcaacc ccaaatcaga aaactctttg caacctatcc aggcggtctc
     9661 atcactgttt cgcatgaccg tcgtttctta aaagaagtct gctcgatcat ctatcgcatg
     9721 acagaacacg gtttgaagct agttaattta gaagatttat aaatttgcaa catagcaaaa
     9781 atccagagac gacctctgga ttcttttaca tctgttttaa acgttcaatc cgttctgaga
     9841 taggtgggtg ggtataaaag agtttttgga accccccacc tttcttggga tcattgatat
     9901 aaagagcact gctagcatca tcgacgtggc gactcatcgg tttgctattg tccaacttat
     9961 ctagggcatt aatcattccc tggggattgc gagtcagctc aacactagat gcatctgcca
    10021 gaaattccct ctgacgagaa atagcgagct gaaccaaggt tgcagcgaga ggtgccagta
    10081 caatagctag tagggaaacc actagcataa tgatttcaag accatttcca tctcggtcat
    10141 catcacttcg tctgcgacct gctccacccc accacatcat acgacctgcc ataccagaaa
    10201 gcatggtgat agcactagca agggcaactg caatagtcga aatacggata tcataattac
    10261 gaatatgact gacttcatgt cccataacag cttctagttc ttcacgattc atgatagcta
    10321 gtagacctga agtcgcagca acagccgcat tttgaggatt agaacctgtc gcaaaggcat
    10381 ttaaggctgg atcatcaatg atgaaaacac ggggcatagg aatctgagcg accagagcca
    10441 tatcttccac tacatggtag aggtctggtg ccgtttgctc atccacctca cgcgctccat
    10501 tcatggacat gacaatctct gtcgattgaa aaatcataga caaagcgtag ataaagccga
    10561 taatcagtgc gataaccaaa ccaccaagtc cagatcttat aaagagataa ccaaccgcat
    10621 aaccaacaag agctaagagt aggaaaaata ccagcaacaa aatccaggtt tttcgtttat
    10681 tgcttgcaat ttgatcaaac aacatcttag tcacctaaac cgctaaaatc aactttagga
    10741 accgactttt cctcttcagg tgtttgaagg aaatctgccg ctttaaatcc aaacattcca
    10801 gcgataatat tgctcgggaa agtttctaat tttacattgt agttgctgac aacactgtta
    10861 tagagttgac gagagtaaga aattttattt tctgtgtttg tcaactcctc ttgcaattta
    10921 acaaagttag cactagcttt caaatctgga tagctttctg caactgcaaa aatacctgaa
    10981 acctgacgag tgagggcatc actggctttc atagcttctg ctggtgaagt cgctgccgcc
    11041 acttggttac gtagttctgc caccttttca agggtagaac cttcatattt ggcataacct
    11101 tttacagtct caatcaagtt cggcaagagg tcatttcgac gtttcaactg aacatcaatc
    11161 tgactccaag cctccttggt ttgcatacga tttttaacca aaccgttata gctaacaatc
    11221 acaaaaataa caataagagc gataactcca agaataatcc aagtcataat ataagtcctt
    11281 tctgctttta gattagtacc agtatatcaa attttctatg attgtggtaa aataagatga
    11341 tactaaagaa ggaaataact atgaaaccaa aaacatttta caacttgctt gccgagcaga
    11401 atcttccact ttcggaccag caaaaagaac aatttgaacg ttattttgag ctcttggtcg
    11461 agtggaatga gaagattaat ttgacggcga ttacggacaa ggaagaagtt tatctcaaac
    11521 atttttacga ttcgattgca cccattcttc aaggtttgat tcccaatgaa actatcaaac
    11581 ttcttgatat cggggctggg gcaggatttc ctagtctacc aatgaaaatt ctctatccgg
    11641 agttagatgt gaccattatt gattcactca ataagcgcat caacttccta caactcttgg
    11701 ctcaagaact ggatttgaac ggagttcatt tctaccacgg acgtgccgaa gattttgccc
    11761 aagacaagaa cttccgtgct caatatgatt ttgtaacagc tcgtgcggtt gcccgtatgc
    11821 aggtcctatc tgaattgacc attccctacc ttaaggttgg tggaaaacta ttggcactca
    11881 aggccagcaa tgcgcctgag gaattattag aagctaagaa tgccctcaat ctccttttta
    11941 gtaaggtcga agacaatctc agctacgccc taccgaatag agatccgcgc tatatcacag
    12001 tggtagaaaa gaaaaaagaa acaccaaata aatatccacg taaggctggt atgccaaata
    12061 aacgcccact ttaaattttt tagtaaacaa atgtttacaa aatcagcctc gctcttttat
    12121 ttctaggctc gggaaaaaat gatttacaaa atcatttttt tctgctatac tatcctaagc
    12181 aaaggttttt aatgtcatcc cgtgaggtga cgaagacgca gaaatattta aaactcttta
    12241 aaatctaaat tttaaagaag tcttactctg agggcctatt gctgtaaaat aatgggctct
    12301 tttttgatgc ccaaaagtga ggtttatatg aaacaagaat caactgttga tttgttacta
    12361 gacgttgacc aacgtccttc ggctggaaaa ggaattctcc ttagtttcca acacgttttc
    12421 gccatgtttg gtgcgaccat cttggtacca ttgattttgg gaatgcctgt atctgttgcc
    12481 ctttttgctt caggtgttgg aacactcatc tacatgcttg ctactggttt taaagttcca
    12541 gtttatctag gttcttcatt cgcctttatc acagctatgt cactggctat gaaagaaatg
    12601 ggggggatgt atctgctgct caaacagggg ttatcttgac tggtttggtc tatgtccttg
    12661 ttgctaccag catccgattt gtaggaacaa aatggattga taaactcttg ccaccaatca
    12721 ttatcggtcc tatgatcatc gttatcggtc ttggacttgc aggttcagct gttaccaatg
    12781 caggtcttgt agcagacgga aattggaaaa atgctctggt agccgttgtt actttcctaa
    12841 ttgctgcctt tatcaataca aaaggaaaag gcttcctacg aatcattcca ttcctctttg
    12901 ccattatcgg tggttacctc ttcgcactaa ctcttggttt ggttgacttt acgcctgtcc
    12961 tagaagctaa ctggtttgaa attcctggtt tctacttgcc atttagcaca ggtggtgcct
    13021 ttaaagagta caatctttac tttggtccag aagccatcgc tatcttgcca atcgctatcg
    13081 taacaatttc tgaacatatc ggagaccata ctgttttggg tcaaatctgt ggtcgtcaat
    13141 tcttaaaaga accaggtctt caccgtactc ttcttggtga cggtatcgca acttctgttt
    13201 ctgccttcct tggtggacca gccaatacaa cttacggaga aaatacaggg gttatcggta
    13261 tgactcgtat cgcttctgtc tcagttatcc gtaacgctgc cttcatcgcg attgccctca
    13321 gcttccttgg taaattcact gccttgattt caactattcc aaacgctgta cttggtggta
    13381 tgtcaatcct tctctatggg gttatcgcca gcaatggttt gaaagtcttg attaaagaac
    13441 gtgttgattt cgctcaaatg cgaaacctca tcatcgcaag tgctatgttg gttcttggac
    13501 ttggaggagc tatccttaaa cttggtccag ttacactttc aggtactgcc ctttcagcca
    13561 tgacaggaat catcttgaac ttgatcttgc catacgaaaa taaagactaa gagtctaaat
    13621 acacctaatc cactcagaca gctgagtgga tttttcgtat accataataa aagtgtctta
    13681 acaaaattat taaaatcaaa aaacgtataa tatcagatat tctaaaacct tgatactgta
    13741 cgttttatca tagaaatttt tactttattt tctcatcaaa tgagatttgc atcaatctct
    13801 tgtcttactt gcgtttcttc ttcgctttct tcattttgtt agccatacgt ttcatggact
    13861 gtttcatggc aaattcacca attttacctt tcaaaccgcc accaaacatc tggctcatat
    13921 ctggcattcc tgctcctccg agagctgata agtcaggcat accgccttgt cccatcattc
    13981 cttcaagggc agacatatcc attcctccca tatttggcat atttttagga aggttatttg
    14041 gattaatccc catttgcttc atcattttat tcatatcccc agacataaca ccctgcatga
    14101 gctgtttagc ctggttaaag tccttgatga atttattgac ttcgacgaat gtatttccag
    14161 aaccagcagc aatacgacgg cgacggcttg gatttaacaa atctgggttt tcacgctctt
    14221 caggtgtcat cgaagacaca atggcacgtt tacgagcaat ctggcgttca tccaccttca
    14281 tgttttgaag ggctggattg ttggccatac ctggaatcat cttgagcaag tcttccatcg
    14341 gccccatatt ttgcacctga tctaattgat cgatgaaatc attaaaatca aaggtgtttt
    14401 cgcgcatctt ctcagccatt tcaagggctt tttgttcatc gtattcctga gaagctttct
    14461 caatcaaagt gagcatatcc cccatgccaa ggatacggct agacatacgg tctgggtgga
    14521 aggtttcgat atctgtaatt ttttcacctg taccagtgaa cttgattggt tttccagtga
    14581 tgtgacgaac agacagagca gcaccaccac gagtatcacc atcaatcttg gtaaggatga
    14641 ccccagtcac ttccaactga gcattaaact cacgcgcaac attggctgct tcctgaccaa
    14701 tcatagcatc aacgacaagc aagatttcat ttggttgagc caatactttc acatcacgaa
    14761 gctcattcat gaggagctca tcaatctgca aacgacccgc agtatcaatc aagacatagt
    14821 cgttatgatt agtttgggct tgctccaaac cttgacgtac aatctcaaca gctggtactt
    14881 ctgttccaag tgcaaagaca ggcacatcaa tctgttgtcc caaggtctta agctggtcaa
    14941 tggcagctgg acgataaata tccgccgcaa tcatcaaagg acgagcattt tcttctttct
    15001 tgagtttgtt ggccaattta ccagcaaagg ttgttttacc agccccttgt aaaccaacca
    15061 tcatgatgat ggttggaatc ttaggtgact tgataatttc tgccgtatca gaacctaaaa
    15121 cggctgtcag ttcctcatca acgattttaa taatctgttg cgcaggatta agcgtatcaa
    15181 tgacctcatg cccgactgca cgctcacgaa ctttcttgat aaagtccttt acaacaggca
    15241 aggcaacgtc ggcctcgagc aaggccaagc gaatttcttt ggttgcctct tggacatcag
    15301 attcagagat ttttcctttt ttacgtagat ttttaaagac gttctgcaaa cgttctgtta
    15361 aactttcaaa tgccattttt cttcctctta ttctctatta tcaatgcttg ttaaaatttc
    15421 tatctgctcc tgcagaaagt catccttggg atagcgctcc aaaatctgat caaaaatctg
    15481 actgcggaca atatagtccg agtacatgtg caatttcatc tcataatctt ccagaatctt
    15541 ttctgttcgc ttgatattgt catagacagc ctgacgactg acaccgaact cctcggcaat
    15601 ttcagcaagg ctgtaatcat cagcgtagta gagctcgata taattcattt gcttatctgt
    15661 caaaagcgcc gcataaaatt caaagagcgc attcatacga ttggtttttt cgatttccat
    15721 aacttttatt ataccaaaaa ttagcctaat ctaccacact aggaagccga tccaagaaga
    15781 tagatagcta aatttgaaaa agacatgagc ctagccccaa gtaatttcca attgatagct
    15841 ggcaaaggga tgtccctctt gattttgtag ttgataatct agttcaatct tttgcccatc
    15901 cacttgataa cgattcgttt ggataataaa ctcctgcata cccataggtg tgggaatata
    15961 ggctaaacta tcactatcct ttagaaagcg cataatggtc ttgggattgg aaaatcgact
    16021 catcacaagt tcttgaccat gaaatttaat cactactttt tccttttcct cattatagaa
    16081 aagcaggtag ctataatctc ctttttcatg cacttccaca tcataaagct ggtcaatcac
    16141 ttccaactgc tcatcaaact gaattgtatt tcgcatccga atcttcacat caggccctct
    16201 ttcttgtctc ttgtcctact attttaccaa aaagagcagg attttgctat aatggtcata
    16261 tgaacgaaaa agtattccgt gaccctgttc acaactacat ccatgtcaat aatcaaatca
    16321 tctatgactt gattaataca aaagaatttc aacgtttgcg ccggatcaaa caactgggaa
    16381 cttccagtta taccttccac ggtggagagc atagtcgctt ctctcactgt ctaggagtct
    16441 atgaaattgc acgacgcatc acagagattt tcgaagaaaa atatcctgag gaatggaatc
    16501 ctgccgagtc tctcttgacc atgaccgctg ctctcctaca cgaccttggg catggtgcct
    16561 actcccatac ttttgaaaat ctctttgata cagaccatga agccattact caggagatta
    16621 ttcaaaatcc tgagacagag attcaccaag tcctgctaca agtggcacct gatttcccag
    16681 aaaaggtggc cagtgtcatt gaccatacct atcctaataa gcaggtcgtg cagctcattt
    16741 ctagccagat tgatgcggac cgcatggact atctcttgcg tgactcctat tttacaggag
    16801 catcctatgg ggaatttgac ctgactcgaa tcctccgagt cattcgtcct atcgaaaatg
    16861 gtatcgcctt tcagcgcaat ggcatgcacg ccatcgaaga ctacgtcctc agtcgctacc
    16921 agatgtacat gcaggtttat ttccaccccg caacacgcgc catggaagtt ctcctacaga
    16981 atcttctcaa acgcgccaag gaactctatc ctgaggacaa ggatttcttt gcccgaactt
    17041 ctccacacct cctgcctttc ttcgaaaaaa atgtgacctt gactgactat ctggctctgg
    17101 atgatggcgt gatgaatacc tacttccagc tttggatgac cagtcctgac aagattcttg
    17161 cagatttatc gcatcgcttt gtcaaccgca aggtctttaa atccattacc ttttcacaag
    17221 aggaccaaga tcaacttact agcatgagaa aattggttga ggatatcggc tttgatcccg
    17281 actactacac tgccattcat aagaactttg acctccctta tgatatctat cgtcccgaat
    17341 ctgaaaaccc acggacacag attgagattt tacaaaaaaa tggagaactg gccgaactct
    17401 ctagcctgtc tcctatcgtc caatcccttg ctggcagtcg ccacggagat aatcgctttt
    17461 attttccaaa agaaatgttg gaccaaaaca gcatctttgc aagcattacc cagcaatttt
    17521 tacacttgat tgagaacgat cattttaccc caaataaaaa ctagaagagg aattttatga
    17581 gtattaaact aattgccgtc gatattgacg gaaccctagt caacagccaa aaggaaatca
    17641 ctcctgaagt cttttctgcc atccaagatg ccaaagaagc tggtgtcaaa gtcgtgattg
    17701 caactggccg ccccatcgca ggtgttgcca aacttctgga cgacttgcag ttgagagacc
    17761 aaggtgacta tgtggtgacc ttcaatggtg cccttgtcca agagactgat actggccatg
    17821 agattatcag cgaatccttg acctatgagg attatctgga tatggaattt ctcagtcgca
    17881 agcttggtgt tcacatgcat gctattacta aggacggtat ctataccgcc aatcgcaata
    17941 tcggaacata cactgtgcac gaatcaaccc tcgtcagcat gcctatcttc taccgcactc
    18001 ctgaagaaat ggctggcaag gaaattgtca agtgtatgtt catcgatgaa ccagaaatcc
    18061 tcgatgctgc gattgaaaaa ataccagccg aattttacga gcactactct atcaacaaat
    18121 ctgctccttt ctacctcgaa ctccttaaaa agaatgtaga caagggttca gctattactc
    18181 acttagctga aaaactagga ttaaccaaag atgaaaccat ggctatcgga gacgaagaaa
    18241 atgaccgtgc catgctggaa gtcgttggca accctgtagt catggaaaac ggaaatccag
    18301 aaatcaaaaa aatcgccaaa tacatcacca aaacaaatga cgaatccggc gttgcccatg
    18361 ctattcgtac attggtactg taaaaggaaa gaatagataa aaaccgctca gctgagcggt
    18421 ttttgatgtc taattactgc cccctgcagg aatcgaacct gcaactactc cttaggaggg
    18481 agttgttata tccattgaac taagggagct agataaaaac tctgctgaaa agcagagttt
    18541 tttagtcgaa ttaacgacgg atttctttga tacgagctgc tttaccttga agagcacgca
    18601 agtagtacaa tttcgcacga cgtactttac cgtaacgaac aacttcgatt ttttcaacac
    18661 gtggagtgtg gattgggaag atacgctcaa cacctacacc gttagagatt ttacgaactg
    18721 tgtagttttc tgagattcca gcacctttac gtgcgataac aacaccttca aaaatctgga
    18781 tacgttcacg gttaccttcg acaactttcg cgtgtacacg aacagtgtca ccaggacgga
    18841 atgatgggat atctgtacga agttgacctt cagtcaagct ttggattaat ggattcattt
    18901 tattctccta tctttgtcaa tcttgaggaa tcttcctcag cggataaact gtatttttgt
    18961 gcgtccatta cacacaagat atagtttacc aaatttctaa aaaaaagtaa agaaatttat
    19021 agcaaaattc ctaaaaaaat cgcaaccaaa ccacctatgt aagtcaaagt caggtaagaa
    19081 taaaagacct tcttatcact tagcagtctt tgaagttcgt cattcaaggt cgaaaaagtt
    19141 gttaaaccgc cacaaaatcc tgttgctaga atagcatata cttccttaga ctctacatga
    19201 ttgtagaata ctccaattaa aaaacaacct aaaagattag ctatgagcgt tccgagtggc
    19261 aatttagaag cttgattata gcgagaaaag aaataccgta cgagtgctcc gaaaccacaa
    19321 gcaattgcaa gatagacgat taccatttct tcctccctag aaaataagct aagagtaggc
    19381 ctccaccgat gctcaaaagc aaatacagga ctaaactaag ataacgccct gtatcaagca
    19441 gcttcacagt atcaagcatt aggctggaaa aagttgttaa acctccgcaa aaacccgtcc
    19501 ccagtgctaa aatcaagccc ttactagtcc ccttatagac cagatagccc ttgacaagaa
    19561 aaatcaagca gaaaattccc agatagttga caaagagagt gccccaagga aagtctggac
    19621 tggctggtaa ccaggtggaa actagatatc ggacaagtcc gcccaacata gcagctagaa
    19681 aaattcctag cggataaaat tgttcttttt tcatttgata ttttgatcct gataatcacg
    19741 cgaacgtttg agtatgtccg aaaaagtcgc gacaatagtc tcctgatagc gcttgtcctc
    19801 tacacgactc ctaacctttt caaaaataac ttcttctctc ttagtatcta aaatcggttt
    19861 acctgaagct ttcttataag caaccacccc ctcaactaaa tgcattcgtt cttctaacag
    19921 tttgacaatt tggtcgtcga tttgatcgat ttcttgacga ataatatcta aatccataca
    19981 gtctcctcct ttatttgaat tattgtatca aaaagccatc aattaggcta gtaaaatccc
    20041 aactctcgat aagaaaaatg cactgattga ttacatcagc gcacttttat gtttatccta
    20101 ctttagcagc caattcttct gcgaattgtt ccaagcgttc aatatcttct tcctcggcag
    20161 aaagatcaac tttaacacac tctgaacctt tttctgctcc tgttgacaca aagacacggt
    20221 caaagtcatc aacagcctta cagaattcat cgtagaaggt atctcctgag ccgaccactc
    20281 cgtagatttt gccattcaag ttgagatctg ctaggtcttc gtagaagtcc atcatctcat
    20341 ctggcaattc accatcacca taagtatagg tcgcaacgat agcgatgtct gcttccaaga
    20401 agtctgaagc gtcaacagtt gtacattcat caacatcaac atccaagccc aagtcacgta
    20461 atttgtctgc tacaatatct gcaatttctt cggtattacc ggtcatactg gcaaatacaa
    20521 tttttgctaa tgccatatcg tcctcctcaa tttatctttc tccattatat cacatctttt
    20581 tcattttaaa aataaaaatt cttgtgctac aatgaaatga gaaagaattg aggttattta
    20641 tggagatttg ccaacaaatt ttagaaaaaa ttaaagaata cgacaccatt atcattcatc
    20701 gtcatatgaa accagaccct gatgccttgg gaagtcaggt gggattgaaa gccttgctgg
    20761 aacatcattt cccagaaaaa accatcaaag ccgtcggttt tgatgaacca actcttactt
    20821 ggatggctga gatggatctt gttgaagata gagcctacca aggcgcactt gtcatcgtct
    20881 gtgatacagc taatactgct cgtatcgatg ataagcgcta tagtcaaggt gattttctca
    20941 ttaagattga ccaccatcca aatgatgatg tatacggtga cctgtcttgg gtcgatacta
    21001 gttcaagtag cgctagcgag atgattaccc tatttgccca aacaacccaa ctagccttgg
    21061 cagatcgcga tgctgagttg ctctttgcag gaattgtcgg tgatacaggt cgcttcctct
    21121 acccttctac cactgcacgg actcttcgcc tggctgctta tttgagagaa cataactttg
    21181 actttgcggc tctcactcgc aaaatggaca ctatgagcta caaaattgct aaactgcaag
    21241 gctacatcta cgaccatctg gaagtggatg aaaatggtgc tgctcgcgtt atcctgagtc
    21301 agaaaatctt gaaacaatac aatataaccg atgctgaaac tgcggccatt gtaggtgcac
    21361 ctggacgcat tgacagagtg agtctctggg gaatttttgt cgaacaggct gatggccact
    21421 accgagttcg cttacgcagt aaagtccatc ctatcaatga aattgccaag gagcatgatg
    21481 gtggaggcca ccctctagca agtggtgcta attcctatag cctagaagaa aacgaaatca
    21541 tctaccaaaa gttaaaaaac ttgcttaaaa actgataaaa tacttgccaa acttttcaga
    21601 atctgataga ctagtatagt aacaatctat ggctcgcaaa gagaccatgg cagaaaggaa
    21661 atattgcaaa atgaaaaaag atatccatcc agaatatcgc ccagttgtct tcatggacac
    21721 aactactggt taccaattcc ttagcggttc aacaaaacgc tctaacgaaa cagttgagtt
    21781 cgaaggcgaa acttacccat tgatccgtgt ggaaatttca tcagactcac acccattcta
    21841 cactggacgt caaaagttca ctcaagcaga tggacgcgtg gatcgtttca acaaaaaata
    21901 cggtctcaaa taatgataag agaacagttt tggctgttct tttttgtttc ttgaaatcaa
    21961 ctgctgtttt catgttccag actcatctgt aggttcgatt tccatgctac taggcaggaa
    22021 ggaaatagct gtttcaacac gtccataatg agctatacta ttgtcacgaa ccacactttc
    22081 attgatggtc caagtggaat tcattttctt aaaagcttct cggacttttt ccaaatcttt
    22141 ggaggcaatg gcctgctcta aggtttcaaa acgaggactt agacggttta ccaatttttc
    22201 cttttccgca tctaggtcaa caggattttg ttctttttca aaagctaata gagctgagga
    22261 aatttcggtg agtttggctt cagtaatatc tccagataga gctaactttt ccttaacaat
    22321 cttaccaacc tcagaatcct tattttctac tctttcgaag tctgatgcca tcttcgtaac
    22381 gagtttctgg gtctcagtct gaccaccatt tttaaccgtt ttggatgcat ctgtgatttt
    22441 cacaaagaaa aaactcaagc tttcttgggc acctgctggg gaaagaatta aaaatgacaa
    22501 agctaaaact agtaaccagc ttttagcctt ccaataattt ctgaccaatg tagcctcctt
    22561 tctccacacc accaaagcaa gtaaaaagtc cactacctat gtgagtgatg tattcattca
    22621 tcttatcagt agcacctagg ttagtttgaa ccttaacaaa gttatcagga tccttctgga
    22681 aagaaatgaa gagcaatccc gtatcaaact gaccagtctt ttcatcaatg ccatctgagt
    22741 aagaataaga acgacgtaaa agtggcttat ccacttcttt ggccaaacaa acatgcgaat
    22801 catcaggtaa gagactcaaa tccacttcat caaactcatt tttcttacca aagggggcac
    22861 cgctttcctt gtaacgacca aaggtatttt ctcgttcttc gagactagtg cggtcccagg
    22921 tctctaaaaa catctgaatc cgacgaactg ccatataaga accattttcc atccagtcct
    22981 tactatcagc ccagataacg cggtcaaagt cttgctcctt ggttggattt gctgttccat
    23041 ccttaaaacc aaagaggttc cacggagtct ccattcgatc cccgatagct gcaaatccag
    23101 actgactcca acgaaggggc accgcatttc tccccttacg gatgagattg cgaatagcgt
    23161 gaaaggcaat ttgctcatca tctgcacaag catgaatcac aatatctcca ccagtatatt
    23221 tttcacgtaa ttgctcctta ggaaatagag gtaaatccct gaacagtcga gggcgcttgt
    23281 tttccaagtt catccttttc aagaaacttg cagatacacc aaaagtcagc gtcaaacgat
    23341 gaggattgag cccaactgtc tcaccagtat cgctcggagg aaagagagca ttctgtccat
    23401 cttttttaac caattccccc tcgaccaact tggcactata atccgtccaa tccttgaata
    23461 gctggataat tttatctcta tccgtcgtat gcaggtccaa gacaacaaaa tagatattct
    23521 tttgcatggg cgtactattt ggtacatcaa gcgaacctta tgaaaaggtc tactggtttt
    23581 aaagcgcttt cttttcttct tgaattgaga ttttattttt agacgcgaca atggtttgag
    23641 cgtctgcttt cctaggatgt tctggacgtg g
//
LOCUS       DAVLZG010000025        23514 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLZG010000025 DAVLZG010000000
VERSION     DAVLZG010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.025"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..176)
                     /gene="blpI"
                     /locus_tag="VYO72_001030"
     CDS             complement(<1..176)
                     /gene="blpI"
                     /locus_tag="VYO72_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1707423.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGS"
     gene            457..2610
                     /gene="blpA"
                     /locus_tag="VYO72_001031"
     CDS             457..2610
                     /gene="blpA"
                     /locus_tag="VYO72_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEV1707424.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2621..3982
                     /locus_tag="VYO72_001032"
     CDS             2621..3982
                     /locus_tag="VYO72_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1707425.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSIISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4039..4194
                     /gene="blpC"
                     /locus_tag="VYO72_001033"
     CDS             4039..4194
                     /gene="blpC"
                     /locus_tag="VYO72_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1707426.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(4239..5579)
                     /locus_tag="VYO72_001034"
     CDS             complement(4239..5579)
                     /locus_tag="VYO72_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1707427.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(5593..6330)
                     /locus_tag="VYO72_001035"
     CDS             complement(5593..6330)
                     /locus_tag="VYO72_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707428.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6335..6673)
                     /locus_tag="VYO72_001036"
     CDS             complement(6335..6673)
                     /locus_tag="VYO72_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707429.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6949..7278
                     /locus_tag="VYO72_001037"
     CDS             6949..7278
                     /locus_tag="VYO72_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1707430.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7446..8495)
                     /locus_tag="VYO72_001038"
     CDS             complement(7446..8495)
                     /locus_tag="VYO72_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707431.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8492..9223)
                     /locus_tag="VYO72_001039"
     CDS             complement(8492..9223)
                     /locus_tag="VYO72_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707432.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9291..9701
                     /locus_tag="VYO72_001040"
     CDS             9291..9701
                     /locus_tag="VYO72_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1707433.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9711..9998
                     /locus_tag="VYO72_001041"
     CDS             9711..9998
                     /locus_tag="VYO72_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707434.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10159..10335
                     /locus_tag="VYO72_001042"
     CDS             10159..10335
                     /locus_tag="VYO72_001042"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707435.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTHIYTASRR"
     gene            complement(10364..11500)
                     /gene="dnaJ"
                     /locus_tag="VYO72_001043"
     CDS             complement(10364..11500)
                     /gene="dnaJ"
                     /locus_tag="VYO72_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1707436.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11705..12058)
                     /locus_tag="VYO72_001044"
     CDS             complement(11705..12058)
                     /locus_tag="VYO72_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707437.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(12071..13894)
                     /gene="dnaK"
                     /locus_tag="VYO72_001045"
     CDS             complement(12071..13894)
                     /gene="dnaK"
                     /locus_tag="VYO72_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1707438.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14374..14898)
                     /gene="grpE"
                     /locus_tag="VYO72_001046"
     CDS             complement(14374..14898)
                     /gene="grpE"
                     /locus_tag="VYO72_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1707439.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(14925..15959)
                     /gene="hrcA"
                     /locus_tag="VYO72_001047"
     CDS             complement(14925..15959)
                     /gene="hrcA"
                     /locus_tag="VYO72_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1707440.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16123..16632)
                     /locus_tag="VYO72_001048"
     CDS             complement(16123..16632)
                     /locus_tag="VYO72_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1707441.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17239..19572
                     /locus_tag="VYO72_001049"
     CDS             17239..19572
                     /locus_tag="VYO72_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1707442.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19585..21048
                     /locus_tag="VYO72_001050"
     CDS             19585..21048
                     /locus_tag="VYO72_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1707443.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21048..22616
                     /locus_tag="VYO72_001051"
     CDS             21048..22616
                     /locus_tag="VYO72_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1707444.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            22673..23470
                     /gene="psrA"
                     /locus_tag="VYO72_001052"
     CDS             22673..23470
                     /gene="psrA"
                     /locus_tag="VYO72_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1707445.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT         7543 a         4660 c         4328 g         6983 t
ORIGIN      
        1 gaacctacac aaataagtgt tgctgctccc ccagttatcg gaccagtcgc agcagctaat
       61 agtactgctc caatacaacc accgattgca gatcctaaat tgcctcttcc tccactaact
      121 atttcgagtt cttcattatc cataacagaa aattgttcca tcatttttgt attcatgaca
      181 aatactcctt ttttattttt aatttttgtc ttgttgcaac tttgacaagt ttagtatatc
      241 attatttttt aatttttttc atccaaatct tgaattgcca tcgaaacgtc ttgaattagc
      301 ttttttattt caagccacct ctaaatgttt aaaaaaaata atttctaatc acttttttac
      361 cattcaggaa gttttaatga ctattcaaca tttcataaaa tatgaactta gttttatggc
      421 ataatatacc tatccactat atgaaaggaa ttgccaatga cttcttataa acgtacattt
      481 gttcctcaaa tagatgcgag agactgtggt gtcgctgcct tagcctcgat tgctaaattc
      541 tatggttcag atttttctct agctcacttg agagaacttg caaagaccaa taaagaaggg
      601 acgactgctc ttggcattgt aaaagccgct gatgaaatgg gctttgaaac aaggcctgtt
      661 caagcagata aaactctctt tgacatgagt gatgtcccct atccatttat cgttcacgtt
      721 aacaaagaag gaaaactcca acattactat gttgtctatc aaacaaagaa agactatctg
      781 gttattggtg atcctgaccc ttctgtaaaa atcactaaaa tgtcaaaaga acgctttttc
      841 tctgaatgga ctggagtagc tatttttcta gctcccaaac ccagctatca accccataaa
      901 gataaaaaga atggtctact aagcttcctt cctctgattt tcaaacaaaa atctctcatt
      961 gcttacattg ttctctcaag cttattggtc actattatca atataggtgg ttcttattat
     1021 ctccaaggaa tcttagatga atacatccca aatcagatga aatcaacttt aggaatcatc
     1081 tcagttggtc tggttatcac ctatatcctc caacaagtca tgagcttctc cagagattat
     1141 ctcctaaccg ttctgagcca gagattaagc attgatgtga ttttatccta tattcgccat
     1201 atttttgaac ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacgg
     1261 ttcacagatg ctaactctat tatagatgcc ttggcttcta ccattctttc tcttttcctg
     1321 gatgtttcta ttctgattct tgtagggggc gtcttactgg cacaaaaccc taatctcttc
     1381 cttctttctc ttatttctat tcctatatac atgttcatca tcttttcttt tatgaagcct
     1441 ttcgaaaaaa tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc
     1501 gaagatatca acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa
     1561 aatatagaca gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct
     1621 attttacaaa caagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg
     1681 tttggcgctc aattagtcat gtcgagtaaa atttctatcg gtcagctgat tacctttaac
     1741 acactttttt cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc
     1801 caatctgcga aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt
     1861 caagttcaag aaaaccctgt tcattcacat tttttgatgg gcgatattga atttgatgac
     1921 ctttcttata agtatggttt tggacgagat accttaacag atattaatct cacgattaaa
     1981 caaggagata aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa
     2041 atgattgtca atttctttga accctacaaa gggcatattt ccatcaatca tcaggatatt
     2101 aaaaacattg ataaaaaagt cttgcgccgt catattaatt acctacccca acaagcctat
     2161 atctttaatg gctctatttt ggaaaactta accttgggcg gtaatcatat gattagtcaa
     2221 gaagatattc taaaagcttg tgaagtagct gaaatccgtc aagacattga aagaatgcct
     2281 atgggctatc aaactcagct ctctgatgga gctggtctat caggaggaca gaagcaacga
     2341 atcgctctcg ctcgtgctct tttaactaaa tctcctgttt taatactaga tgaagctact
     2401 agcggtcttg atgtcttgac tgagaaaaaa gttatagata atcttatgtc cctaactgat
     2461 aaaaccattc tctttgtagc ccatcgtctc agtatagccg aacgaaccaa ccgtgtcatt
     2521 gttcttgacc aggggaaaat cattgaagtt ggtagccacc aagagttaat gcaggcgcaa
     2581 ggtttctacc atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag
     2641 aagcgtcgag ttttatcaga gacgttacca taactatgcg acagtgttaa ttatacctct
     2701 ttcattacta tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt
     2761 cacttcccaa ggagaaatcg cccctacaag tatcatttca tctattcagt caaccagtga
     2821 taatcctatc cttgctaatc atttagtggc aaatcaagta gttgaaaaag gggacttact
     2881 catcaaatac tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca
     2941 aagacttgag aagcaaaaag aaggacttgg aattttgaaa caaagcttag aaaaagcgac
     3001 tgatcttttt tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa
     3061 acaatcccat gatattgaac tgggtatcac aaagactaac actgaggttt caaatcaagc
     3121 taatcttgcc aatagcagtt catcagctat tgaacaagaa attacaaaag ttcaacaaca
     3181 aattggagaa tatcaagagc tgagagatgc tatcataaat aacagagcac gcttaccaac
     3241 tagcaatcca caccagtcaa ttttgaatcg ttatcttgta gcctcacaag gacaaacaca
     3301 aggaacggca gaggagccat ttttatctca aattaatcaa agtattgcag gtcttgaatc
     3361 atctatcgca agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa
     3421 tagtttagca accaaaattg aagtactccg cactcaattt ttacaaacag cttctcagca
     3481 acaactaacc gtggagaacc aattaacaga attaaaagta caactagatc aagcgacaca
     3541 gcgcttagaa aacaatacct taaccgctcc aagtaaaggt atcgttcatc tgaacagcga
     3601 atttgaaggt aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctatcat
     3661 cacagataca agagaagtac taatcactta ctacgtagct tctgactatc tacctctact
     3721 agataaagga caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcattaccat
     3781 catcggccaa cttcagacaa ttgatcaaac tcctaccaga acagagcaag gcaatctctt
     3841 taaattaacc gctcttgcaa aactatctaa tgaggatagt aaactcatcc aatatggctt
     3901 acaaggtcgc gtcactagtg taactgcaaa gaaaacatat tttgattatt tcaaagataa
     3961 aattttaacc cattctgatt aattttcaga taacactcta taactattta ttatcttatc
     4021 aaaaaggaga atcataacat ggataagaaa caaaacttaa cttcatttca agaactaaca
     4081 actaccgaac tcaaccaaat tacaggtgga ggactgtggg aagatatctt atacagcctt
     4141 aatataatta agcataacaa tacgaaagga cttcatcatc caatacaact ataaaaaata
     4201 agaccgagta acaagaactc tcggtcttat ttttttcatc attctgtagg tatcatagta
     4261 agcacctgac gaaagacttg atcttgacag gtagtattta aactggcatt gggataactt
     4321 tccacaatct tcataacggt atagagaccg acacctctct cctccccttt agaactaact
     4381 ccaaaggaga agatttcaga aatatcgatg ccctcttctt tgatggagtt ttcaatgata
     4441 aaagtctcct gtgctccact ttttaaaaag gcaattgaaa catgaggttg accggcctct
     4501 gcactcgctt caatagcatt atcacaaagg atagacacaa tggttagaaa atcaagcagt
     4561 ctcatcccct caacctgaat ctcttcagga acttcgacat taaagacaat gtccttttct
     4621 ctagctttta taaattttcc agctaggaga cttttgaggg cacgatcccg aacattcacc
     4681 aatctgccca ggtcatattt attgtcctgc aatttctgac tggaatccct taagaccaag
     4741 tcatagacct cttttatctg ctccatatcc tcctcttcaa tacccagacg taaacttgtc
     4801 aagaggttgg tgtagtcatg gcgaaaactc cttacttcct tgtaaagttc ctctatatgc
     4861 cgactatagc gttctatatc tctatagcgc aagacctgct cttggtccag tctatcatgg
     4921 agtttgtcct tcaaataggt atccaatttc ttgataaccc ccataaaaaa taggaggtaa
     4981 aacactagaa tgagatggcg aacagtcgtt gattgaatac cttgctcata ttcaaagtaa
     5041 gacagacttt gtatcaccaa atagtaagcc cccattatcc agttaatctt agtcagggac
     5101 ttttgaaaac ctgtatctag aatctccctt ctcaaactag taaaatcata gtccaaccat
     5161 ttcaaaaagg ctagagaaat gaagaaattg aaaattatta tacataaccc agtaaatgag
     5221 tagccatcat atacttgctc ttgtcccaaa aatggaagca caaaatagga gactcctcta
     5281 taaaagagat tcaccaatat cattggaaag agaccataaa agaaaaggag ttttttagga
     5341 agccctctta acaataagaa agacaagcct atgccgtaca agggttccat aaaataagat
     5401 aggtaaacat ttcctaccat atagccaatc attacaaaaa caaaggccaa cagtatcttc
     5461 aaaagaaagg ccttaaaaat cctctcaaaa gtgagaccaa ttccatctac cttaaagaaa
     5521 atgacaattt ttaatccgtg agtaacaagt gtatacaaca atatccaagc aacattcata
     5581 aactctccta gctcagtgta agttattaat agcctcagac acttccctga ccttataacg
     5641 cgcgatcaga cagcttccac cattgggaaa gaaaaggagt ttttctttct tatccaaatg
     5701 caccacattt gcaggattga tgagaaaaga gcgatggcac tgcaagagac ggggttcctg
     5761 cttaaaaacc tcctctaaac tcgccgtaaa ttctagcctg tccgtcttgg tatagagaat
     5821 aacacgatgg ggtcttgggg atgtttcgag atagtaaacc tctttgaaag gatattggaa
     5881 ttgggcaaat tttgatttaa agtaaaagca atcttccgcc agacttttac tatcttgact
     5941 attggcatag aggagggctg tctcgatacg agattcaaac tcctctgccg aaagggcctt
     6001 atcaatgtag tccaaagctg acacttggta gcgaaaggac agaggcataa actccgagtg
     6061 agtcgtcaca aagacgatta gggcataagg gtcttgttcc cgaatctttc tagctacttc
     6121 cagtcccttc atctcttcat ttcgaatctc aatatccaaa aagaatagct gatgggcccc
     6181 cttctcatgc acctctgcca gcagttggtc cggcttgcca aatacctcaa aagagctagg
     6241 aatgatatga tgtgctttca aaagtttctc aatcgtcgtt tcaattctag tctgttggga
     6301 aaaatcatct tctaaaacaa atattctcat cttcttactc tccctctttc aaccattttt
     6361 gacgtatttc tctatagcga cgtctggcat acttgacagc atattgacct tcttctccga
     6421 gaaaaaggat tctttcttga aaatcaatcg attttaattt atcaagatta accaaacaat
     6481 ttcgatgaca tctcatcaaa gtttccccac attggttctc aagattactt aaattttgaa
     6541 gcatattaaa actagctttt tctgtaacaa tctgtacggt atgggcttta gttggatgtg
     6601 tttggatata gtagatatcg tcgatgttta ctttatagac tgttttctgt gtctgaataa
     6661 tcatatgttt cattggattc tcctcctaag aaaagaataa cagaaaaggt ctagcccaag
     6721 cacacccaat cctaaacagt ctttgaaaac tcctaaaagg attattttct acaacatcat
     6781 gatgagctta caactatttt atcataaaat tcactcagcg caattcaaga catttcaatg
     6841 acaattaaag atttgaataa aaaaaaagaa ttaaaagtga taaactaaca gtatcaaaac
     6901 acagttgcca gaagtaagac tggcacccag attaaaggag gcattcccat gacagataca
     6961 gaccccatca aaagagctca tactttgatt actgacttaa acaaagccta ccaagcatgc
     7021 aaacaggcaa gcgctgacga cgtccgcttt caggagcaat taaactctat tcttggtttt
     7081 ctagccaagg ctgaaacagt ggataatcga ttcttgattg aactagaaaa attttaccag
     7141 acttccagtc ttctcatggg actcagcgct cttgatccag atgctccaac tcgcgccgct
     7201 tggcgggcct atgaccgctt ccactttgac caagtcaaga ccaagttaat actcaatgag
     7261 aatcaaagag caaactagga agctagccgc aagctgtact tgagtacggt aaggcgacgc
     7321 tgacgtggtt tgaagagatt ttcgaagagt ataagtctct acggaccaac cattatcctg
     7381 tagtaacaaa aaagaagctg agacagactg aactcaactt cttttttagt gtcgtatcag
     7441 caatgttagt cctgcatctg acgttttacc tgataaggca aatacaagac tagtaaaacc
     7501 aaaccagctc ctagtaaggc tagaagggcc agtttttctt ggaaggtaat caacccaaca
     7561 actaattcca caagtaaaac aaaactggtc aatcctcgaa ctacctcctg taagcctttt
     7621 tccttttgcc ccttgtccag cggaaagagt tgggtcaaat actggtagtc aaaggcatga
     7681 tagagggcca gcaactggaa gagcaagagg tagttaaaga gaactaccac tgctgtcgca
     7741 atccaagctt gctcgataaa aacctgcgcc agtacggaaa gtaatagaag acgaagactg
     7801 agagcaaaga ggtcgccatt tcgcagataa gaacgcagat agagattttg ccaaatcttc
     7861 ccaggcacct tctgaacagc ctttaagata aagtccagat aggcacgacg cttaacgctg
     7921 tttgaaattc ccttgacctg cgtaaagagg gcaaagaaac gaagcaagac ttgcttacgc
     7981 ttgctttctt gagaaataac atagtcccag tccagtccag tttcagtgaa aaatttgctg
     8041 gccttttgac gaaagtggaa atattttcct acccccaata aaagcacata gagcagaaaa
     8101 actggcaagc cataacccat tgctaaaaat aaaggcgcaa ataacagcaa gaaaagggtc
     8161 tgtacaaaga gccaaaagac tagggaaatg ccagtttgac gcttgagatg gagcttgatt
     8221 tcctcttctc caactaagag aaagagcttg tctggagcct ccatataggt ggcaattcct
     8281 ccccaaagta aaagtaaaac agacgtaatt cctacaaaca aaaggatagg ccaatgattt
     8341 tcaggaaaat gttgtaagag ttgactgtac tggtaggcta gaaagcccaa caggacaagc
     8401 aggaacaaga caaagtggtc attgagcaca tagcgcagat aaccaagaca ctccttacga
     8461 aaggcctgct ttctctttaa aaacaagtct ttcataggtc ctcctctttt gtcagagcca
     8521 agtaaatatc attcaaacta gcctcaggca tatcaaaggc ttcgcgtagt tgcaggagat
     8581 tgcctttggc acgcacctct cccttgtgaa gaatgacaaa ggcatcacac atcttctccg
     8641 ccgaatccag cacgtgggta ctcatgagaa tagacttgcc cttttgcttc tccacttcca
     8701 aaagctgaat caaatcagaa atagccagcg gatcaagacc aaggaaaggc tcatccacga
     8761 tgaaaagact tggatccacc acaaaagcac agataatcat gaccttctgc ttcatccctt
     8821 ttgaaaaatg aacagggaac cagtctaatt tctgttccaa acggaacatt tttaacaagg
     8881 gctctactcg ttcgaaagcc actttttgct caataccgta agccatagca accgtttcga
     8941 tatgctctct gagggtcaat tcctcataca gactaggcgt ctcaggaatg tagccaatct
     9001 gcttgcggta gctagtcgca tctccttgca gagtcaggcc attgatattg atggagccac
     9061 tataaggtgc caacagaccg ataatctcat tgatcgtcgt tgatttccca gcaccattga
     9121 gaccaatcaa accgaccaac tgcccacttt caacagtaaa ggacacatct ttcaaaacag
     9181 gaacatgaac atagccacct gtcaggtttt taatttctaa catattttct ccaaatctgg
     9241 tataatgtag ctatattata tcaaaattca gtacagtaga ggtagatttt atgtcagatt
     9301 gcattttttg taaaatcatc gcaggggaaa ttcctgcttc aaaagtatat gaagatgagc
     9361 aggtccttgc ctttcttgat atctctcaag taacactagg acacaccttg gtcgtgccaa
     9421 aagaacacta tcgcaatctt ttggagatga atgctacgag cgccagccaa ctctttgccc
     9481 aagtaccaaa agtagctcaa aaagtcatga aagtcactaa ggctgctggt atgaatatca
     9541 tttccaactg tgaagaagtc gctggtcaaa cagtttttca tactcacgtt caccttgtgc
     9601 ctcgctacag tgctgacgat gacctcaaga ttgattttat cgcccacgaa ccagactttg
     9661 acaaacttgc tcaagtcgct gaaaccatca aaaacgctta aggagttgct atgaaattat
     9721 ccaacctact gctatttgca ggagctgcag ccggaagtta tctggttaca aaaaatcgcc
     9781 aaaccatcac agatgaagtc ttaaatacca ctgaccgcgt tcaagctatc aaagacgatg
     9841 tggatattat ccaaaatagc ctgcaaatca tcgaccagca aaaagaactt atcaaggaat
     9901 accaagaaga cttgacttac aagtttaagg tcttggaaaa ggatatccag actagactag
     9961 ctgtgataaa agaaatgcag ggaactgaag ataagtaaaa agagcccccg gctctttttt
    10021 aaaacgtaaa caagttatag tgaattgaat ttagaatagc acatcatagt ttctaaagca
    10081 ttgttagaga ttactttaaa atcctcttat caatttgttc atattctatt tcaatctact
    10141 atatatatcc catcaactat gcatcataat ttaggtaact catactcaat aaaaatcaaa
    10201 aagcaaacta gaaagctagg cacagactgc tcaaaacacc gttttaaggt tgtggataga
    10261 actgacgaag tcagctcaaa acactgtttt gaggttgtag atacgactca catatatacg
    10321 gcaagccgac gctgacgtgg tttgaagaga ttttcgaaga gtattattct ccatcaaagg
    10381 catctttaat atggtcaaag aagccttttt tctttggatt tactttcaag tcaccagcag
    10441 ccgcgaattc tttcaaggct actttttggc ggtcgttcaa gcctgtcggt gttacgacat
    10501 taacagtaac gtattggtca ccaactgcac cgccacgaag gctcggtgcc cccttactac
    10561 gtaggcggaa tttcttacca gtctgagttc cctctggaat aaccaattca acatcaccgt
    10621 gaacagttgg aatatctact gtatcaccaa gagccgcttg gacaaagttg aggttgagat
    10681 tgtagaagat agtcgttcct tcacgttcaa acttgtcgct agcttctaca gaaactacta
    10741 catacaagtc accataaggt ccaccgttaa agcctgcttc accttgacca gcgaggcgaa
    10801 tttgttgacc tgtttccaca ccagcaggga ttttcacatg tacgctatga gcttgtttct
    10861 catgacctgt tccatgacag gttgtacatg gatatttgat ttcttttcct cgaccgtgac
    10921 agacatcaca ggttacttgg cgacgcatca taccaagagg agtctgcgta tcgacgttaa
    10981 tgacaccagc gccatgacag cgtccacaag tgactggact tgtccctggc ttagcaccag
    11041 agccattaca tgtacgacag ccagcttcac gatgatactt aacttccttc tcagttccga
    11101 agatagcttc ttcaaaggtc aaattgacac gatactggag atcatctcct tggcgaggag
    11161 cgtttggatt gcgcgaagaa ccgcctccgc cgaagaaact tgagaaaata tcctcaaaac
    11221 caccgaagcc acctgcccca ttgaaaccgc cgaaaccacc agctccacca aaaccaccat
    11281 tggcgcctgc agcaccatac tggtcatagg cagcacgttt ttggtcgtca ctcaaagtct
    11341 cataggcttc ttgaacttcc ttgtacttgt cctcagcacc aggctccttg ttgatatctg
    11401 ggtgatattt tttggaaagc ttacgataag cctttttgat ctcgtctgcc gaagcgtttt
    11461 ttgacacccc cagacgatca taaaattcag tattgttcat acaagatacc aagaccgtaa
    11521 aattcgactg aaaaatagga aatctgacgc tggagcgacg ctcctagaca gatttctctt
    11581 ttttccgaga atttaggtcg ggttcaattc ctttctttta tattgatgag ataatactcc
    11641 agccactcgg ccctatccct ttttaccgaa aaacagaggc tgggttgcaa cctctgtggt
    11701 tagattattc atttgaaata aaaatggttg tattatctct agtagtaatc ttcaaagacc
    11761 ttttagctaa atcaaactca aatttattat agtgtgggtc ttgtgtttta tataggtgta
    11821 actcctgaca tatatgatcc gaaaagtaaa tcataacatc tttaaacaca gaagtgtagt
    11881 catatttact cttaccaaca gctacttctg taaattcttt ataaatgaca tttccatttc
    11941 tttccacagt caccagcatt tctgttggat tataatccaa attaaataat tcttcaaaaa
    12001 actttatctt ttcatgataa tctgcaatgt cagaaagatt atttttatta acactcataa
    12061 cactagcccc ttacttttcc gtaaactctc cgtctacgac gtcatcgcct gcgtttcctg
    12121 ttgcttgtgc gccttctgct ccttcttgag cttgttgcgc tgctgcggct tgttcgtaga
    12181 gtttaacagc aagtccttga gctttttcgt tcaatgcttc aagttttgct ttcatgtcgt
    12241 ccaagttgtt gtcttcttga gctttcttaa ggtcatcaag ggcagcttgg gcagcgtcac
    12301 gttctgcgtc gaagccttta ccttcagttt ccttgattgt cttttcagtc gcaaagattg
    12361 cttggtctac ttcattacga aggtctactt cttctttacg tttcttatcg gcttcagcgt
    12421 ttgcttctgc atctttcatc atgcggtcga tttcttcgtc agtcaaacct gagttcgatt
    12481 ggatgacaat agtttgttct ttttgagttc caaggtcttt ggccttaaca gacacgatac
    12541 cgttcttgtc gatatcaaat gttacttcga tttgaggaat tccacgaggt gcagctggga
    12601 tatcagtcaa ttggaagcgt ccaagagtct tgttatctgc tgccattggg cgttcacctt
    12661 gaagaacgtg gatatcaacg gctggttggt tgtctgctgc tgttgagaag acttgtgatt
    12721 tagatgttgg gattgtagtg ttgcgatcga taagttttgt aaatactcca cccattgttt
    12781 cgataccaag tgacaatggc gttacatcaa gaaggacaac atccttgaca tcaccagtaa
    12841 tcacaccacc ttggatagcc gcacccatag caactacttc atcagggttt actgatttgt
    12901 ttggttcttt accagtttca gctttaacag cttcaacaac ggcagggata cgagttgaac
    12961 caccaacaag gataacttcg tcgatttctg acaagctcaa acctgcatct gaaagggctt
    13021 gacgaactgg aacttttgta cgttcaacaa ggtcacgagt caaatcatca aatttcgcac
    13081 gagttaaagt catttccaag tgaagaggtc cagcctcacc tgcagtgata aatggcaagc
    13141 tgatttgtgt tgaagttaca ccagaaaggt ctttcttcgc tttttcagcc gcatctttca
    13201 aacgttgcat tgccatcttg tcagtagaca agtcgatacc gttttctttc ttgaattctg
    13261 ctaccaagtg gtcaatgatt ttttggtcaa agtcgtcacc accaagtttg ttgtcccctg
    13321 cagttgacaa tacgtcgaag acaccgtcac ccaattcaag gatagagacg tcgaatgtac
    13381 caccaccaag gtcaaatacc aagatttttt cttctttgtc agtcttgtcc aaaccataag
    13441 caagagctgc tgcagttggt tcgttaacaa tacgttctac ttcaagacca gcaattttac
    13501 cagcgtcttt tgttgcttga cgttgagcgt cgttgaagta agccggaact gtgataacag
    13561 ctttggttac tttctcacca aggtagtctt cagcgtagcc tttcaagtat tgaaggatca
    13621 tagctgagat ttcttgtgga gtgtattctt ttccatttgc agaaactttt tcagaagttc
    13681 ccatcttaga tttgatagag ataactgtat ctgggtttgt gactgcttga cgttttgcag
    13741 catcaccaac gatgatttct ccgtttttga atgagactac agatggagtt gtgcggtttc
    13801 cttctgggtt tgcgatgatt ttgctttcag ttccttcaag aactgcaact gctgagtttg
    13861 ttgtacctaa gtcaataccg ataattttag acatgtgttt ttctccttgt tagttaattt
    13921 tctatttttc tttttgatac tcttcttaag tggcgacgcc gtcagagctt gacttcgtca
    13981 atctctttga ctaaactttg agcctaaggt ctcaaaattt gcgcaaatag cgccacggcg
    14041 aagagtatcg tgtttggttc gcttcgctca ctattacaaa gccaaacata ttttatcttt
    14101 cttcatagtt tattgtcgtt tcggacaagt tttctattat gtaaattgcg acacgaagag
    14161 tcgaaatcga ttttatttcg acgacgagtt agtaaggaag ctaggcaaac gccatagcga
    14221 ttgccgtttt ctgacgagtt gctttagcta ccgtcagaat tgccgaatcg aacacgccct
    14281 aagctctgag taaaaaagat agattttctt gtgttcatcg aacacttcgt caatctccta
    14341 tttttactgc gagcttttta cgggctttgt atcttagtta tacaccacta ccattgctgg
    14401 gcgtaggatg cggtcatgga gtttgtagcc tttttgaaag acttgagcga tggtatctac
    14461 tgggtgttca tcgtctgctg ggagagtttg gatggccata tggtagttat ggtcaaattc
    14521 gccatctgct gcgatttctt caattccttc ttctttcaaa gcgtgaatca agctttcttg
    14581 caccatcccc aagcccttct tcacatcatc tgtcaaacct tcaactgcaa gtgcacgctc
    14641 aaggttgtca agagatggta agattgcttt tgccaagtcc tggctacgat aacgttgcaa
    14701 gttttgacgt tcttcattgg cacggcgttg gatattttgc atttctgcat gagcgcgaag
    14761 atatttgttt tcgaactcat ctgcacgttc atttgccaag tccaactcag acttttcagg
    14821 agttgtttct tcagctgttt ccacaacttc ctcttcttga acttcttcta cttcttcatt
    14881 ttttatatct tgggccatgt tcgcctcctt taatgatttc aatcttaatg tacttcgtaa
    14941 tgattactgc tgaggtagcg gtaaaaatct gtcaacttca tggtcaaaac acggttgacc
    15001 acattgattt gattgattag ctgttggtaa tccagattaa ctggaccgat aatggctaga
    15061 attccaactc cccgataagg aatgaggaac ttactactaa tcaccgctag gtcagctaaa
    15121 caggactctt gaccgtctgc aatacgaaca ttttgcatct gatcctcacg caacccctca
    15181 cgaatctcca aggccacctt ttgcggttgg tcaaagaact gataggctgc tagattggca
    15241 aaattcaaga gattgacctt gcccgccatc acaatgtttt cgttgaacat ttccttaaag
    15301 atgtgttcaa agagatcgat gacattatcc gttgttgtaa agtaacgctg gataatctgc
    15361 ggaatctccg tccgaatctt gtagtgaata tctaaaacgg tgtgaccgag gaaacgttcc
    15421 tgaatgatgc tcttcagttt cagcaaatcc tcctgcaaga agttccttgg aatcagaaac
    15481 tgactagtaa ccgttcgcga ctcgtctagg gtaaataccg ccaaggctgt atgttgcccc
    15541 aaaacaacga tatcaaaggc tgtcaaacgt tgcctgctcg gctcaacatc cagtgccact
    15601 accgtacagc cactcaggtc tgttagcaag ttagcagcct cttgcagaat atcctccaat
    15661 ttgaagaatt cctgatcaaa ggctttgaca atctcatata cctcattttc agccagccgg
    15721 tgaaaatcca gtgagtgttt cacatagtac tgaaaaccag caacacttgg catccgaccg
    15781 cttgaagtat gagccttctc aagcaaccct tgtttttcta gttccgccat gtcattacga
    15841 atggttgcac tgctagagtt aatagactct tgcaaggctt ttgatccgac aggttcgtgc
    15901 gttttggtaa agatgtcaat aatcagattt aaaatatcct gctgacgctc tgtaaccatc
    15961 tcatcactcc tctctgtctg atcaattagc actcaatgca tccaagtgct aacttatgat
    16021 tctattatac acccttagaa gagaatgtca agacaaaaac tcaaaaaatt agcactcttt
    16081 tatcaagagt gctaaaaatc aatctgaaga cctagaacct tgctattcat ctactcggta
    16141 tttccttttt agtctgaaat aaccatgaat tagataagaa atcagaaaag catataaaac
    16201 aaaaataaga aagaaagaca tagaaagatc ctctctaaac aaactcgtac aaacaacaag
    16261 accacctaag aaagtagttg tacaggaacg aagtctagat cgcataactt cccatttgag
    16321 ccccttactc atatagactt gatcctctgg aagtaaatca gaagacgatt tacgaagaat
    16381 cgaacaagaa cctgctccta tcaattccca acctctatct ctaaaatctt gcagttcatg
    16441 cttatatttt ttaagaaatc tagaatcata gatacggtag atgacatcgt ctggttgaca
    16501 ttggtcaaaa tagaacaaac caaaacgact cgttctatac ctccaacctt tcaaatgcat
    16561 ctcatgtaaa tattcttctt ccttgtccaa atcaacaata gtgaaaatcc gaaattctac
    16621 tctgctattc attgtcttac cccaaaatta gaaaacatgc ctggcgttat ttattagata
    16681 attctttccg cttttgactc aatctccaaa aaatataaga aatctgaatc gcaaaaacta
    16741 tcaataaaac ccaatctatt atgaaagtca aaaacacttc ccaactgaaa gaactacctc
    16801 cagtgacaaa ctttgagaaa aacggtagta gagctaaaaa gagaagcaaa ataggaagca
    16861 tccgcattgt taaaatcctt ttggcataaa aaaatcttta tttaaacgaa aatattatgg
    16921 caaaatttac gccagttttt gaacggctga tgtagatatt ttatactttc aaaatgttta
    16981 aatgtgatta tttatttttg aaaaatagct caccagcccg actgaaagtg cttataaatg
    17041 ataataagtc gcctgccgaa aacagcgaaa aatagcggtg ttatgcggag ataatctgac
    17101 gcgatgcgaa agtatattgc atacttattt tcaacaattt agcagagtat ttttataagt
    17161 gtgatataat agaagtataa tttgttctga tagtttattt tatggagaag tagattttta
    17221 gaatgcggag ggttcaatat ggttgagttt ataaagtcta agaaagaaat gagtgaggag
    17281 gatattaaag caaatttcat cactcctgct attgtatcca aaggatggaa aaatggtgag
    17341 catatcgctt acgaagaata cttcactgat ggtcgaattg aggttagagg agataaggct
    17401 cgtcgtaaag aaggaaaaaa atcagactat tcactgtatt accaatttgg aactcgaatt
    17461 gcaattgttg aggcaaagga taataaacac agcgttcgag caggattaca acaagctatt
    17521 gaatatggag agattttaga tgttccattt gtttattctt cgaatggtga tggctttatt
    17581 gaacacgacc gtatcacgag agaagaacgt gagctggagt tagacgaatt ccctactcgt
    17641 gaagaattat tttctcgtat gacgaaggaa aaaggattga cgtacgaaat tacagaagct
    17701 atctcaactc catactatac agacgccttc tcaatgaaaa cgccacgcta ttatcagcaa
    17761 atagctatca accgtactat tgaaacagtt gccagaggac aaaaacgagt aatgtttgtg
    17821 atggcaacag gaacggggaa aacgttcatg gcttttcaaa ttattcatcg ccttcgaaaa
    17881 gctggtttgg ctaaacgagt tttattctta gcggatagaa acatcttagt agaccaaacg
    17941 atggctgaag actttaggcc attcgaaaag gtaatgacga aaattacacc aaaacttttg
    18001 actgctcctg aaaaattaaa ttcttttgaa atttatctag ggctttatca gcaactaact
    18061 ggtgaagatg gaactgaaac acattatcaa aaatttgaca aagacttctt tgatttaatc
    18121 gtaattgatg aagcgcaccg tggttcagct aaggaaaaca gtaactggcg taagataatt
    18181 gattatttca gttctgcgac acagattggg atgaccgcta ctcctaaaga aaccaagaat
    18241 gcttccaata cggaatactt tggtgagcca atctatactt atagtttaaa acagggaatc
    18301 gaggatggtt ttttggctcc atatcgtgtt atgagggtta atttagatgt ggatgtggat
    18361 ggttatcgtc cagaaactgg aaaagttgat gctaacggac aattaataga agataggtac
    18421 tacggcagga aagattttga taaaaccatt gtcattgatg atagaacgca aagagttgcc
    18481 aagtttgttt ctgattatat gaagcaaaac aatgcacgat ttgataaaac aattgttttt
    18541 tgtgttgata ttgaccatgc cgagcgaatg cgtgctgcac ttgtaaaaga gaatctagac
    18601 ttagtccaag aagactatcg ttatgtcatg caagtaactg gtgacaacgc tgaaggaaaa
    18661 gctcaactgg ataactttat ggatgtcaat tctaattttc ccgctatggt aacaacgtct
    18721 aaattattaa cgacaggagt taatgctaaa acatgtcgtt tgattgtttt agactctaat
    18781 atccaatcca tgactgaatt taaacaaatt attggtcgtg gcacacgtct ttatcctcaa
    18841 aaggggaaag aattttttac gattattgat tttcgaaatg ttaccaattt gtttgctgac
    18901 cctgattttg atggtgatcc tgtgaaggtg ctggaaacag gtgcgaaaac agtcagtggt
    18961 tctacgcccg gtttcgtaga taaggaaggt gacccagtag aaaaatatat cgttacagac
    19021 aagcaggtta ccattcttaa ttctactgtt caagtattgg atgaaaacgg gaaactgatt
    19081 accgaaagcc tgaccgacta cactcggaag aatatcttag gtagctacgc cactttgaac
    19141 gattttatca cagtttggca tacggcggat aaaaagaagc ttatcttaga cgaactttat
    19201 aaaaaaggag tttatctaga tgctattcga gagtcggagg gaatatcaga acaagaaatc
    19261 gatgattttg atttactcct aaaacttgcc tatggtcaaa aagaattaac caaaacggaa
    19321 cgtatcaata aactcaaaca aagcggatat ttatataaat atagtgagga agcgcgtgct
    19381 gttttggaaa ttttactgaa caaatacatg gataaaggta ttggagaact cgaaagcatt
    19441 gaaacattaa aacttccaga atttcagata tatggtggaa ccttcaaaat catcaatact
    19501 tattttggag ataaaaaacg atatttacaa gcaattaaag aattggagca agagctattt
    19561 acagtagctt aatgaaagga aagtatgtca attacatcat ttgtaaaaag aattcaagat
    19621 atcactcgaa acgatgctgg tgttaatggt gatgctcaac gtattgagca aatgtcttgg
    19681 ttattattct taaaaattta tgatagccgt gaaatggttt gggaattaga agaagacgag
    19741 tatgagtcaa ttatcccaga ggaattaaaa tggcgaaatt gggctcatgc tcaaaatggg
    19801 gaacgggtat tgacaggcga tgaattactt gattttgtca ataacaagtt attcaaagag
    19861 ttgaaagagc ttgaaataac ttcaaatatg cctattcgaa aaacgattgt taaatcagct
    19921 tttgaagatg cgaacaacta tatgaaaaat ggcgtcttgt tacgccaagt catcaatgtt
    19981 attgatgaag ttgatttcaa tagccctgaa gatcgtcatt cgtttaatga tatttacgaa
    20041 aaaattctta aagatattca aaatgctggg aactcaggag aattttatac gccacgtgca
    20101 gcgactgatt ttattgccga agttcttgac ccaaaacttg gagaatcaat ggcagacctt
    20161 gcttgcggaa caggaggctt cttgacttcg actctgaacc gtttaagtag tcaacgtaaa
    20221 actagtgaag ataccaaaaa atataataca gctgtttttg gtattgaaaa gaaagcattt
    20281 cctcatcttt tagcagttac aaatctgttt cttcacgaaa ttgatgaccc taaaattgtt
    20341 catggaaata ctttggagaa aaatgttcgt gaatatacga atgatgaaaa atttgacatt
    20401 attatgatga atccaccttt tggagggtca gaattagaaa caataaaaaa taactttcca
    20461 gcagaattac ggagttctga aacagctgat ttatttatgg ctgtcattat gtatcgtttg
    20521 aaagaaaatg gtcgtgttgg agttatttta cctgatggtt ttctatttgg tgaaggtgta
    20581 aaaactcgct tgaaacaaaa actggtagat gagttcaact tgcatacgat tattaggttg
    20641 cctcatagtg tctttgcacc gtatacagga atccatacga acattctttt ctttgataaa
    20701 acaaagaaaa cagaagaaac ttggttttat cgtttagata tgccagatgg ttataaaaat
    20761 ttctcgaaaa ctaagccgat gaagtcagaa cacttcaatc ctgttcgtga ctggtgggaa
    20821 aatcgtgaag agattctgga aggtaagttc tacaaatcta aatcatttac acctagtgaa
    20881 ttggctgagt tgaattataa tttagaccag tgtggttttc caaaagagga agaggaaatc
    20941 ttaaatccct ttgagttgat tcagaattat caagcggaaa gagcaacttt aaatcataag
    21001 attgataatg tattagctga tattttgcag ttgttggagg acaaataatg acaccagaac
    21061 aacttaaagc aagtattctc caaagagcga tggaagggaa attagtgccg caaaatccca
    21121 atgacgaacc tgcaagtgaa ttattaaaga gaattaaagc tgaaaaagaa aaacttatca
    21181 gtgaaggaaa aatcaaacga gataaaaagg aaactgagat atttcgtggt gatgatggga
    21241 aacattatgg gaagtttgct gatggaagta ctcaagaaat tgatgttcct tatgatattc
    21301 ctgatacttg ggagtgggtg aggttttcta cattggttga aattgtcaga ggtggctctc
    21361 cacgaccaat caaagattat cttacttctg aagtagatgg aataaattgg ataaaaatag
    21421 gtgatactga aaagggtgaa aagtatataa ataatgttaa agaaaaaatc aaaaaatcag
    21481 ggcttaacaa aactagattt gtaaaaaaag gtacattttt gttaactaat tctatgagtt
    21541 ttggtagacc ttatattttg aatgttgatg gtgcaataca cgatggatgg ttggctattt
    21601 cgaactatga aaactcatta aataaagatt atctattcta tattctttca tcaaatgtag
    21661 tttattctca atttctatct ctaattagtg gagctgttgt gaaaaacttg aatagtgata
    21721 aagttgcttc tattcttatc cctctccccc cactatccga acaacaacgc ataatagaag
    21781 caatcgaatc agctttagaa aaagtagatg aatatgctga aagttataat agactagaac
    21841 agctagataa agaatttcca gataaactaa aaaaatctat tcttcaatat gctatgcaag
    21901 gaaaattagt tgaacaagac ccaaatgatg aatcagtcga agttttactt gaaaaaatac
    21961 gagcagaaaa acaaaaactc tttgaagaag gcaagattaa aaagaaagat ttggacattt
    22021 ctattgtttc ccaaggagat gataactctt attatgagga agtaccttgt gaaataccag
    22081 aaagttggga gtgggtgagg ttaaacgata taacctccta cattcaaaga gggaagtctc
    22141 caaaatattc aaatattcct atataccctg tgattgctca gaaatgtaat caatggtctg
    22201 gcttttctat tgacttagca agatttattg atcccgaaac agttcatagt taccagaaag
    22261 aaagattact aagagatggt gatttaatgt ggaattcaac aggtctaggt acgttaggac
    22321 gattagctat ttaccatgaa aataaaaatc cttatggctg ggctgttgca gatagccatg
    22381 ttacagttat aagagtctta tcgggagtta ttaattgcca tttcatctat aattttcttt
    22441 cctctcctat tgttcagtca gttattgaag aaaaagcgtc gggtagtaca aaacaaaaag
    22501 aattattaac gaaaactata aaagaatatt taatccccct cccacccctt cctgaacaat
    22561 ccagaatcgt tgataaaatc gaacaatttt tcgcccatat tgacgcacta atttagtata
    22621 atagttttac gtgcggtgga atttctatca aacataagat aggagtttta cgttgaaaga
    22681 ttttgaatta catttgaaga aagctggttt agctgaaaat actgtgcgtt cgtaccttta
    22741 tggtgttcga tttttcttgg agaattacga actcaaaatg gaagatttat ttgaatacaa
    22801 aggatattta ttagacaatt ttaaacctaa aactgtcaat ttgcgactac aaggagtaaa
    22861 taaatatctg gcttttattg gtcatgatga tttgaaatta aaatttgtca aagtacagca
    22921 aaaaccgttt ttagaagatg tcattagcca tgctgattac ctttttctta aacgtagttt
    22981 gaaaaaagat ggtattttaa aatggcattt tgtcgtttgg tttttaggtg caactggggc
    23041 tcgtgtaagt gaacttatta aactaaaagt agagcatgta gaaatcggtt attttgacat
    23101 ttactcaaaa ggtggtaaaa ttcgtagact gtacattcct aaaaaattaa gaaatagttg
    23161 tcttagttgg ttagaatcag aaaatcgccg aagtggttat ttatttttga ataaatttaa
    23221 cgaaccaatt acagcaagag gagttgctca acagttaaaa aattatgctg ataaatacaa
    23281 aatgaatcct aaagtaattt accctcattc ttttagacat ttatttgcta agaatttttt
    23341 agcgaagtat aatgatattg ccttgcttgc agatttgatg ggacacgaaa gtatagaaac
    23401 tactcgaatt tatctaagga aaacagctac tgaacaacaa aatattgtag ataaaattgt
    23461 taattggtaa aaaataacag gtggtcaaac tgactacctg ctatttttgt gatt
//
LOCUS       DAVLZG010000026        22902 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLZG010000026 DAVLZG010000000
VERSION     DAVLZG010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.026"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            371..754
                     /locus_tag="VYO72_001053"
     CDS             371..754
                     /locus_tag="VYO72_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1707446.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            806..1495
                     /locus_tag="VYO72_001054"
     CDS             806..1495
                     /locus_tag="VYO72_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707447.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1537..1770
                     /locus_tag="VYO72_001055"
     CDS             1537..1770
                     /locus_tag="VYO72_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707448.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFLGAGYVVGFWLLILNENQRAN"
     gene            1921..2532
                     /locus_tag="VYO72_001056"
     CDS             1921..2532
                     /locus_tag="VYO72_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707449.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFVPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYKSWPLLYYL"
     gene            2693..3487
                     /locus_tag="VYO72_001057"
     CDS             2693..3487
                     /locus_tag="VYO72_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1707450.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETVPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3484..4119
                     /gene="trmB"
                     /locus_tag="VYO72_001058"
     CDS             3484..4119
                     /gene="trmB"
                     /locus_tag="VYO72_001058"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1707451.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4245..4724
                     /gene="rimP"
                     /locus_tag="VYO72_001059"
     CDS             4245..4724
                     /gene="rimP"
                     /locus_tag="VYO72_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1707452.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4768..5904
                     /gene="nusA"
                     /locus_tag="VYO72_001060"
     CDS             4768..5904
                     /gene="nusA"
                     /locus_tag="VYO72_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1707453.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            5926..6219
                     /locus_tag="VYO72_001061"
     CDS             5926..6219
                     /locus_tag="VYO72_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1707454.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6212..6511
                     /locus_tag="VYO72_001062"
     CDS             6212..6511
                     /locus_tag="VYO72_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1707455.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6528..9320
                     /gene="infB"
                     /locus_tag="VYO72_001063"
     CDS             6528..9320
                     /gene="infB"
                     /locus_tag="VYO72_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1707456.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9571..9921
                     /gene="rbfA"
                     /locus_tag="VYO72_001064"
     CDS             9571..9921
                     /gene="rbfA"
                     /locus_tag="VYO72_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1707457.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            10200..10979
                     /locus_tag="VYO72_001065"
     CDS             10200..10979
                     /locus_tag="VYO72_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707458.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQDPTTLLSQEILDRVANACIRDNLLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            10981..11163
                     /locus_tag="VYO72_001066"
     CDS             10981..11163
                     /locus_tag="VYO72_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707459.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(11506..11580)
                     /locus_tag="VYO72_001067"
                     /pseudo
     CDS             complement(11506..11580)
                     /locus_tag="VYO72_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11611..11844
                     /locus_tag="VYO72_001068"
     CDS             11611..11844
                     /locus_tag="VYO72_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1707460.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            11844..13178
                     /locus_tag="VYO72_001069"
     CDS             11844..13178
                     /locus_tag="VYO72_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1707461.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            13188..13442
                     /locus_tag="VYO72_001070"
     CDS             13188..13442
                     /locus_tag="VYO72_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1707462.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            13538..13933
                     /locus_tag="VYO72_001071"
     CDS             13538..13933
                     /locus_tag="VYO72_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1707463.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            14346..14795
                     /locus_tag="VYO72_001072"
                     /pseudo
     CDS             14346..14795
                     /locus_tag="VYO72_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
     gene            14782..15339
                     /locus_tag="VYO72_001073"
     CDS             14782..15339
                     /locus_tag="VYO72_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707464.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            15341..16303
                     /locus_tag="VYO72_001074"
     CDS             15341..16303
                     /locus_tag="VYO72_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1707465.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            16315..18966
                     /locus_tag="VYO72_001075"
     CDS             16315..18966
                     /locus_tag="VYO72_001075"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1707466.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELDRLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            19037..19792
                     /locus_tag="VYO72_001076"
     CDS             19037..19792
                     /locus_tag="VYO72_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1707467.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            19814..19975
                     /locus_tag="VYO72_001077"
     CDS             19814..19975
                     /locus_tag="VYO72_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707468.1"
                     /translation="MKEREVLTGQRLNELEINGIRLTKFKNGEIGIEFIWIDTENPPS
                     DAIGWVAKK"
     gene            20078..21063
                     /locus_tag="VYO72_001078"
                     /pseudo
     CDS             20078..21063
                     /locus_tag="VYO72_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            21166..22860
                     /locus_tag="VYO72_001079"
                     /pseudo
     CDS             21166..22860
                     /locus_tag="VYO72_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         6952 a         4098 c         5185 g         6667 t
ORIGIN      
        1 accccgttac tgttcatttt aaatattatt ggcctgtctt gcttttcagt gctaacatac
       61 attaacataa aagagatact cttaaatata agtaaatgat gatttggtta gtcctagaac
      121 caatcaactt atgtttatcg gcttggcaga ttttatgttt gtcatttgtt tgtatagagg
      181 tatttcagaa acagaattct atcaacaact aatcgcttat ataggtgtat tctctgcttg
      241 tttatcacgc ttctgctcat gtggggcttg aagtattata aaaagtagct ttctatcctt
      301 ttctgacagg atatttgagt agaaggctct attaaattgt tagtgaaata aatgaatgga
      361 ggtatttaat atgaaataca gattattttt tgttattttc ttgagtagtg tgttggatat
      421 tcttttaggg acatttttac aaatctctat cgtatctatt gggtggcttg ttctttacag
      481 tggtttgttt gaagcaggag ttttccttct tgctaataaa ggggtggcgg taaaaatcaa
      541 ggaagtagat attcgaaatc gctttaaatt tatttttgga aaaaccttat ggtttcaaat
      601 tcttttgctc atctttttga taatcaaact ttatcttggt ttggatgcga ggttgatttt
      661 attctatgga catattttca ttgtctttaa tgccttaatg tatctattat ctagtagtca
      721 ggttagcctt aaaaaaaaca aactgtcttc ttaatcttac agcagtagag cctgacaagg
      781 tgaggtcata gtagggagga tttctatgaa aaagtatcaa cttctattca aaataagtgc
      841 agtcttctct tacttatttt tcgtatttgg tctttctcag ctgacgctta tcgtccaaaa
      901 ctattggcaa ttttcttctc agataggcaa tttattctgg attcaaaata tcttgagttt
      961 actttttatt ggagtcatga ttgtggttct tgttaagaca ggccatggtt atctcttccg
     1021 cattccaaga aaaaaatggc tttggtattc gattttgaca gtattagtgg tagtgttaca
     1081 gatctctttt aacgttcaga cagctaaaca tgttcagtca actgcggaag gttgggctgt
     1141 attgattggt tatagtggga ctaactttgc agagctaggt atttatatag ccctgttctt
     1201 tctggttcca ctgatggaag aattgattta tagaggatta ctgcaacatg ctttctttaa
     1261 gcattcgcga tttggtcttg atttgcttct tccttctatt ttatttgctc tccctcattt
     1321 ttcaagcctg cctagtctgt tagatatctt cgtctttgca acagttggaa tcatctttgc
     1381 tggtttgacc cgctatacca agagcattta tccatcctat gcggtgcatg tgatcaataa
     1441 tattgtagcg accttcccgt ttttgctcac ttttctacat agggtcttgg ggtaaaaaaa
     1501 caaaaggctt gcttttcagc catagaggag gtcatcatgt ataaacactt atttttccta
     1561 gattccaaaa ctttagatcg gttgacaccc tatattctag tcttggcttc tgacaccatt
     1621 gcttttaatg tttttgtgct aacctttgta tctgcggtgg tttttaattt cctaaattcc
     1681 atgctagctt taatggctat cttcttagga gctggctatg tggtcggatt ttggttacta
     1741 atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggctgta cttgagtacg
     1801 gcaaggcgac gttgacgtgg tttgaatttg attttcgaag agtataaaat ggtttgtttt
     1861 ggaaaggcta gaactaaagg atgacgtgta ggaagtctgt ttgttgagga ggataatttt
     1921 atggagtttt ttgataaatt tcatgccttg tgttttggat ttttagtact aataattgtc
     1981 attacagttc cttatacgat taaccatggg gatttttttc aaaatgaatc tgcattgatt
     2041 attgtaagtc ttcttgtaac ctcgctgagt gttgcttatg ctagaaagtt tgaaatgatt
     2101 tcttttggga tgttaagcaa gaaacaactt ttgcttttca ttgcaatctt tcttctaagt
     2161 gtgcttgaga cgctggttta tattcatttc ttcgctgttt cttctggctc aggggtccaa
     2221 cacttggcgg aagtcagcag aggaatttcc ctgtctttga ttttgactac ctcagttttt
     2281 gtccccatcc aggaggaact cattttcaga ggacttcttc aaggtgcggt ttttgacaat
     2341 tcttggttag ggcttgtgct aacttcctct ctcttttctt tcatgcatgg accttctaat
     2401 gtcccttcgt ttatttttta tctacttggg ggcttgttac tgggctttgc ttataaaaag
     2461 agtcaaaacc tatgggtttc tactctagta catatgcttt acaaaagttg gccactctta
     2521 tattatttat aaaaattatg aaaaggtaag cagaagacgg tgcttacctt tttcaagcta
     2581 taatgatacc caagccaatc cagaggcttt tctttgagaa tcgggttaga gtggttgacg
     2641 aataggccaa aaactagtag aatagtaagg aaactttata cggaggaaag aaatggattt
     2701 gggtgataat gagctaacac tgactcccat acctgggaaa agtggcaagg cttatatggg
     2761 tagctatcct gatgggaagc gcatctttgt aaaaatgaac acctctccaa tcctacctgg
     2821 tctagctaga gaacaaattg ctccacaatt attatggagt cgtcgtttgg cagatgggcg
     2881 tgatatgtgt gctcaagaat ggttgacagg caagatattg accccctatg atatgaatcg
     2941 taagcaaatc gtcaatattt taacccgtct tcatcgctca cgtccgttga tgacacaatt
     3001 gagtcgtttg ggctatgcca tggaaacacc tgtagattta ctacagtctt ggcaggaaac
     3061 ggttccagat gctttgcgta aaaatcattt tatcagtgaa gtgatggctg atttacgtca
     3121 gactattcca ggatttagag aggaccatgc gaccattgtc catggagatg tacgacatag
     3181 taattggatt gagacagata gtggcttgat ttatttagta gattgggatt cggttcgctt
     3241 gaccgatcgc atgtttgatg tggcccatat gctctgccat tatatttcag aacatcagtg
     3301 gaaggaatgg ttgacctact acggttacaa gtacaatcaa acggtattaa gtaaattgta
     3361 ttggtatggt caattgtctt atttgagtca gatttccaag tattatatga accaagattt
     3421 agaaaatgtc aatcgggaga ttcatggttt gcgtcatttc cgagacaagt atggaaagag
     3481 aagatgagag ttagaaatcg taaaggggca acagaattac tagaggcaaa tccccagtat
     3541 gtggtcctca atcccttgga agccaaggca aaatggcggg acttgtttgg caatgataat
     3601 cccattcatg tggaagttgg aagtggaaag ggtgcctttg tttcaggtat ggccaagcaa
     3661 aaccctgaca tcaactatat cgggattgat attcaaaagt ctgttttgag ctacgctttg
     3721 gacaaggtgc ttgaagctgg agtgtctaac atcaagctct tgtgggtaga tggttctgac
     3781 ttgactgact actttgaaga cggtgagatt gatcgcttgt atctgaactt ttcagatcca
     3841 tggccgaaaa aacgccatga aaagcgtcgt ttgacctaca agaccttttt ggataccttc
     3901 aaacgtatct tgcctgaaaa tggagaaatt catttcaaga cggataaccg tggcttgttt
     3961 gagtacagtt tagtgagctt ttctcaatat ggcatgaaac tcaatggtgt ctggctagat
     4021 ttgcatgcca gtgattttga aggcaatgtc atgacagaat acgagcaaaa attctcaaac
     4081 aaggggcaag ttatctaccg agttgaggca gaattttaag agatagccta aaattaggct
     4141 gtacaagtgc ttttgcttta cataagttgg caaacgtgct atactgatag taagaatatg
     4201 aaaagtgagg cggggaaata tcttcgcctc ttgcttatga ggaggtggac gcaatcgcaa
     4261 caatcgtaga attagtcaga gaagttgtag aacctgtcat agaagctcct tttgaactcg
     4321 tggatatcga gtatggaaag attggcagtg acatgattct cagtattttt gtagataaac
     4381 ccgaaggaat taccttgaac gacacggcag acttgacaga aatgatcagt cctgtcctag
     4441 acaccatcaa gccagatccc ttcccagaac aatatttcct agaaattacc agtccaggtt
     4501 tggaacgtcc tttgaaaacc aaggatgccg tcgctggagc ggttggaaaa tacatccatg
     4561 tcgggctcta ccaagccatc gataagcaaa aggtctttga aggaactttg ttggccttcg
     4621 aagaggacga gttgactatg gaatatatgg acaagacgcg taagaaaacc gtccaaattc
     4681 catacagttt agtatcaaaa gcacgtttag cagttaaatt atagaaaaag aaaggatagc
     4741 ttttgaggat tcaaaagtga agaaaacatg agtaaagaaa tgctagaggc cttccgcatt
     4801 ttggaagaag acaagggaat caaaaaagaa gatatcatcg acgcagtagt agagtcgctt
     4861 cgttccgctt atcgcagacg ctatggtcag tcagacagcg tagctattga cttcaacgaa
     4921 aaaacaggtg actttacagt ttatactgtc cgtgaagttg ttgatgaagt atttgatagc
     4981 cgtttggaaa tcagcttgaa agatgctctt gccattaatt cagcttatga acttggagac
     5041 aaaatcaagt ttgaagaagc accagctgag tttggtcgtg tagcagccca atctgccaaa
     5101 caaaccatca tggaaaaaat gcgcaagcaa acacgtgcca tcacttacaa tacttacaaa
     5161 gaacatgagc aagaaatcat gtctggtaca gtagaacgct ttgacaaccg ctttatctat
     5221 gtcaaccttg gtagtatcga agcccaattg tcaaaacaag accaaattcc tggagaagtt
     5281 tttgcttctc atgatcgtat cgaagtttat gtttacaagg ttgaagacaa ccctcgtggt
     5341 gtgaacgtct ttgttagccg tagccatcca gaaatgatca aacgtttgat ggagcaagaa
     5401 attccagaag tttatgatgg aactgttgaa atcatgagcg tggctcgtga agcaggtgac
     5461 cgtacgaagg ttgctgttcg tagccacaat ccaaacgtgg atgctatcgg tacaatcgtt
     5521 ggacgtggtg gtgctaatat caagaagatt actagcaaat tccacccagc tcgttacgat
     5581 gctaaaaatg accgcatggt accaatcgaa gaaaatatcg atgttatcga gtgggtagca
     5641 gatccagctg aatttatcta caatgccatc gctcctgctg aggttgacca agttatcttt
     5701 gatgaaaacg acagcaaacg tgccttggtg gttgttccag ataacaagct ttctcttgcc
     5761 attggtcgtc gtggacaaaa cgtgcgcttg gcggctcact tgactggtta ccgtatcgat
     5821 atcaagtctg ctagcgaatt tgaagccatg gaagacgctg cttcagtaga gttggaagta
     5881 gaaaacgata ctgtagaaga ataaaagctg ctagaggagg gaaagatgaa aacaagaaaa
     5941 atccctttgc gcaagtctgt tgtgtctaac gaagtgattg ataagcgtga tttgctccgc
     6001 attgtcaaga acaaggaagg acaagtcttt attgatccta cgggcaaggc caatggccgc
     6061 ggcgcttata tcaaactaga caatgcagaa gccctagagg cgaaaaagaa gaaggtcttt
     6121 aaccgcagct ttagcatgga agtggaagaa agcttttatg acgagttgat cgcttatgtg
     6181 gatcacaaag tgaaaagaag agagttggga cttgaataag caaaagataa gtaatctctt
     6241 ggggcttgct cagcgagcag ggcgcatcat atcgggtgaa gaattggtgg tcaaggccat
     6301 tcaagacggc aaggccaagt tggtctttct agctcatgat gctggaccca atctgaccaa
     6361 gaagattcaa gataaaagtc attattatca agtagaaatt gtaaccgtgt tttcaacact
     6421 ggaattaagc atagcagtcg ggaaatcgag aaaggttttg gctgtaacag atgctggatt
     6481 tacaaagaaa atgaggtctc ttatggaata gaagaggagg acatgatttg tctaagaaaa
     6541 gattgtacga aatcgcaaaa gaacttggaa aagaaagtaa agaagttgta gcgcgtgcaa
     6601 aagagttagg cttggatgtg aaaagccact catcaagtgt ggaagaagct gtcgctgcaa
     6661 aaattgctgc cagctttaag cctgcagctg ctccgaaagt agaagcaaaa cctgcagcac
     6721 caaaagtaag tgcagaaaag aaagccgaaa aatctgagcc agctaaacca gctgtagcta
     6781 aggaagaggc aaaaccggct gagccagttg ctccgaaaac agaaaaagta gcagtgaaac
     6841 cgcaaagtcg taatttcaag gctgagcgtg aagcccgtgc taaagagcag gcagaacgac
     6901 gcaagcaaaa taagggcaat aaccgtgacc aacaacaaaa cggaaaccgt cagaaaaacg
     6961 acggccgtaa tggtggaaaa caaggtcaaa gcaaccgcga caatcgtcgc tttaatgacc
     7021 aagctaagaa gcagcaaggt cagcaaaaac gtagaaatga gcgccgtcag caagaggata
     7081 aacgttcaaa tcaagcggct ccacgtattg actttaaagc ccgtgcagca gccctaaaag
     7141 cagagcaaaa tgcagagtac gctcgttcaa gtgaggaacg cttcaagcag tatcaggctg
     7201 ctaaagaagc cttggctcaa gctaacaaac gcaaggaacc agaggaaatc tttgaagaag
     7261 cggctaagtt agctgaacaa gcacagcaag ttcaagcagt ggttgaagtc gtccctgaga
     7321 aaaaagaacc tgcagtggat acacgtcgta aaaaacaagc tcgaccagac aaaaatcgtg
     7381 acgattatga tcatgaagaa gatggtccta gaaaacaaca aaagaatcga agtagtcaaa
     7441 atcaagtgag aaatcaaaag aatagtaact ggaataacaa caaaaagaac aaaaaaggca
     7501 ataacaagaa caaccgtaat cagactccaa aacctgttac ggagcgtaaa ttccatgaat
     7561 tgccaacaga atttgaatat acagatggta tgaccgttgc ggaaatcgca aaacgtatca
     7621 aacgtgaacc agctgaaatc gttaagaaac ttttcatgat gggtgtcatg gccacacaaa
     7681 accaatcctt ggatggggaa acaattgaac tcctcatggt ggattacggt atcgaagcca
     7741 aacaaaaggt tgaagtggat aatgctgaca tcgaacgttt ctttgtcgaa gatggttatc
     7801 tcaatgaaga tgaattggtt gagcgtccac cagttgttac tatcatggga cacgttgacc
     7861 acggtaaaac aacccttttg gatactcttc gtaactcacg tgttgcgaca ggtgaagcag
     7921 gtggtattac tcagcatatc ggtgcctacc aaatcgtgga aaatggtaag aagattacct
     7981 tccttgatac accaggacac gcggccttta catcaatgcg tgcgcgtggt gcttctgtta
     8041 ccgatattac gatcttggtc gtagcggcag atgacggggt tatgcctcag actattgaag
     8101 ccatcaacca ctcaaaagca gctaacgttc caatcatcgt agctattaac aagattgata
     8161 aaccaggtgc taacccagaa cgcgttatcg gtgaattggc agagcatggt gtgatgtcaa
     8221 ccgcttgggg tggagattct gaatttgttg aaatctcggc taaattcaac caaaatatcg
     8281 aagaattgtt ggaaacagtc cttcttgtgg ctgaaatcca agaactcaaa gcagacccaa
     8341 cagttcgtgc gatcggtacg gttatcgaag cgcgcttgga taaaggaaaa ggtgcggtcg
     8401 caacccttct tgtacaacaa ggtaccttga atgttcaaga cccaatcgtt gtcggaaata
     8461 ccttcggtcg tgtccgtgct atgaccaacg accttggtcg tcgtgttaaa gttgctggac
     8521 catcaacacc agtctctatc acaggtttga acgaagcacc gatggcgggt gaccactttg
     8581 ccgtttacga ggatgaaaaa tctgcgcgtg cagcaggtga agagcgtgcc aaacgtgccc
     8641 tcatgaaaca acgtcaagct acccaacgtg ttagccttga aaacctcttt gataccctta
     8701 aagctgggga actcaaatct gttaatgtta tcatcaaggc cgatgtacaa ggttctgttg
     8761 aagccctttc tgcctcactt caaaagattg acgtggaagg tgtcaaagtg actatcgtcc
     8821 actcagcggt cggtgctatc aacgaatcag atgtgaccct tgccgaagct tcaaatgcct
     8881 ttatcgttgg tttcaacgta cgccctacac cacaagctcg tcaacaagca gaagctgacg
     8941 atgtggaaat ccgtcttcac agcattatct acaaggttat cgaagagatg gaagaagcta
     9001 tgaaagggat gcttgatcca gaatttgaag aaaaagttat tggtgaagcg gttatccgtg
     9061 aaaccttcaa ggtgtctaaa gtgggaacta tcggtggatt tatggttatc aacggtaagg
     9121 ttgcccgtga ctctaaagtc cgtgttatcc gtgatggtgt cgttatctat gatggtgaac
     9181 tcgcaagctt gaaacactat aaagacgacg ttaaggaagt tacaaacggc cgtgaaggtg
     9241 gattgatgat cgacggctac aatgatatta agatggatga tgtgattgag gcgtatgtca
     9301 tggaagaaat caagagataa gattttttgc tcctttctta ggtggtgagg gacgcaagca
     9361 aaccgatggt ttcattgctt atttttgagc ctagggtctc aaaaataccc tgtgatggga
     9421 ctgataaatc agttccatca ctttcaccac ggcgaaagaa gcagatgact tcaaattgaa
     9481 cttcgtttca atttaaactg aaaatcaaga agtttaaaat agctaggtct gctggcctag
     9541 cttttggttc aaagtagaga aaggaatatc atggcaaatc atttccgtac agatcgtgtg
     9601 ggcatggaaa tcaagcgtga agtcaatgag attttgcaaa agaaagtccg tgatccacgt
     9661 gtccaaggtg tgaccatcac agatgttcag atgctgggtg acttgtctgt tgccaaggtt
     9721 tattacacca ttttgagtaa ccttgcttcg gataaccaaa aagcccaaat cgggcttgaa
     9781 aaagcaactg gtaccatcaa acgtgaactt ggtcgcaatt tgaaattgta caaaatccca
     9841 gatttgacct tcgtcaaaga cgagtccatc gagtatggaa acaagattga cgagatgcta
     9901 cgcaatctgg ataagaacta aagaagaggg gttgcccctc ttttttggtg gaggaaaata
     9961 ggttgaattt gaaatggaaa aatattcttt tataatagat tgaaactaga atagtacgcc
    10021 tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttct
    10081 tgtttcattt tactataaaa aaggggttct gtatttttta atgttatcta attagaaaat
    10141 gctttttttg taggaaatat aatatgataa ggtgcaaaaa agaaataagg agtttgtata
    10201 tggctgaaca agacttagct atgcaagtat tgcaacaagt ggtgaaacta cctgttgtta
    10261 aggttgatcg ttcgaaattt ttagtggata agttttccaa agaattggat ccaaaagata
    10321 ttcctacctt attggaacaa gacccaacga ctcttctatc tcaagaaata ttagatcgtg
    10381 tagctaatgc ttgtattcgg gacaatttat tattagcgag tgggacttct gttttggcag
    10441 gattacctgg agggcttgct atggcaatta ccattccagc tgatgtggct caattttatg
    10501 ctttctctct gaaattggct caagaattag gttatattta tggttatgag gatctttggg
    10561 cttcacgcga ggagttgagt gaagatgctc aaaataccct cttgctttat ctaggcgtaa
    10621 tgttaggggt gaatggaacc gctgctttgc tacgtgctgg tggtataaca attgccaaac
    10681 aggtaatgaa aacagtgcct aataaagctt taacaaagac gctttggtac cctattttga
    10741 aaaaagtctt aaaaatattt ggtgtgaatc ttaccaaggg agggctggcc aaaggaatag
    10801 ggaaatttat tcctatcttg ggtggtatca tttcaggtgg tttaaccttt gcaactatga
    10861 aaccaatggg ggaaagcttg cagaaagaat tatccaagct agtcaactat agtgaagttc
    10921 aatatcaaga agatgttgaa acaatccgaa aagaggctga aatcatcaaa ggagagtaat
    10981 atgaatccta tcaaagcttt tgctaaaatt tatggtaatt actttttgac cgtgcaaggt
    11041 gtaaaagtga tgaaaacgat aaagaaagct gaccatgtcg ttgttggtct gggcaaactt
    11101 tttattgcag ataagctaat ggatacggct cggtggctca ttaagccaga ggagagagaa
    11161 tgaaattttt ttggtcttct tgctattctt tttatcaaac cgattattgg gattgtgaaa
    11221 ttcttttgga tgatcatttc ttttgcagtt caattgctgt tttacaagat attggattgg
    11281 ttctttaaac ttatctagat ggtaatccaa gttgcagaga actagcagga actccactgc
    11341 tagtttttta ttctctttcc atatggtata atataagcag taaaatcatt ttatactctt
    11401 cgaaaatctc ttcaaaccac gtcagcttca ccttgcagta tatatgttac tgacttcgtc
    11461 agttctatcc acaacctcaa aacggtgttt tgagctgact tcgtcagttc tatctacaac
    11521 ctcaaaacac tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat
    11581 tgagtattag aacatacaat ggaggtcgtc atggacaata tcatcgatgt gtcaattcct
    11641 gttgcagaag tggtggacaa gcatccagaa gtcttggaaa ttctagtgga gttgggtttt
    11701 aaaccccttg ccaatccctt aatgcgcaat acagttggtc gtaaagtatc acttaaacag
    11761 ggttctaagc tagcaggaac tcctatggac aagattgtac gcacactgga agcgaatggc
    11821 tacgaagtga ttggattaga ctaatgacag atgaacggat tcatatccta cgggatattt
    11881 tgttagaatt gcacaatggc gcctctcctg agtcggttca agatcgcttt gatgcgacct
    11941 ttacgggcgt gtcagccatc gagatttccc ttatggagca cgagctgatg aactcggatt
    12001 cgggcgtcac ttttgaagat gttatggaac tctgtgatgt ccatgccaat ctttttaaaa
    12061 atgctatcaa aggtgtcgaa gtttcagata ctgagcatcc aggtcaccca gttcgtgtct
    12121 tcaaagaaga aaatctggct ctccgtgcgg ccttgattcg cattcgtaga ttgttagata
    12181 cctatgagtc tatggaagac gaggaaatgc tggcggagat gcgtaagggt ttggtgcgtc
    12241 agatgggact tgtgggtcaa tttgacatcc attaccaacg taaggaagaa ctcttctttc
    12301 ctatcatgga gcgctatgga cacgattcac ctcccaaagt tatgtgggga gtggatgatc
    12361 agattaggga actctttcaa acagctctaa cgacagccaa gtcactacca gaagtgtcaa
    12421 ttagcagtgt aaaggaagct tttgaagctt ttgcgacaga gtttgaaagt atgattttca
    12481 aggaagagtc catcctcctc atgattctcc ttgagtcttt tactcaggat gactggcttc
    12541 agattgcgga ggagagcgat gcctatggct atgccatcat ccgtccgtca gagaaatggg
    12601 tgccagaacg acagagcttt attgaggaaa agattgcaga ggagcctgta cagctagata
    12661 cggcagaagg tcaagttcaa caagtcatag atacgccaga aggccatttt accattacct
    12721 ttacccctaa ggaaaaggaa gctgtgctgg accgccatag tcaacaggct tttggtaatg
    12781 gctatctttc agtcgagcag gccaatctca tcctcaatca tctccctatg gagattacct
    12841 ttgtcaataa agaagatatt ttccagtatt acaatgacaa tacgccagct gatgagatga
    12901 ttttcaaacg gacgccgtcc caagtcgggc gcaatgtcga actctgccat ccgcctaagt
    12961 acttggacaa ggtcaaaact atcatgaagg ggcttcgtga gggaagcaaa gacaagtatg
    13021 aaatgtggtt caagtctgag tcgcgaggta agtttgtcca catcacctat gctgcagtac
    13081 acgatgaaga cggagaattc caaggagtgt tggagtatgt tcaggatatc cagccctacc
    13141 gtgagattga tacggactat tttcgtggat tagaataagg agaaaaaatg agttacgaac
    13201 aagaatttat gaaggaattt gaagcttggg tcaataccca aatcatgatt aacgatatgg
    13261 cgcacaagga aagtcaaaaa gtttacgaag aagaccagga cgagcgtgcc aaagatgcca
    13321 tgattcgcta cgagagtcgc ttggatgctt atcagttctt gcttggtaag tttgaaaact
    13381 tcaaagcagg caagggattc catgatttgc cagaaggctt gtttggtgag cgaaattatt
    13441 aaacgagaaa gattcttgat ttttcactaa aatcttgata gaatgtttat gttaaatcct
    13501 tgtcagagca gggatttttt attgaaagga ttttatcatg tcaaagaaac tcaatcgtaa
    13561 aaaacaatta cgaaatggcc tccgtcgcgc aggtgccttt tcaagtactg tgactaaggt
    13621 tgtagatgag acaaaaaaag tcgtgaagcg tgcagaacag tcagcaagcg cagctggtaa
    13681 ggctgtttct aaaaaagttg aacaagcagt agaagctacc aaagagcaag ctcaaaaagt
    13741 agctaattct gtagaagatt ttgcagcaaa tttgggtgga cttccacttg atcgtgccaa
    13801 gactttctat gatgaaggaa tcaagtctgc ttcagatttc aaaaactgga ctgaaaaaga
    13861 actccttgcc ttgaaaggaa tcggcccagc taccatcaag aaattgaaag aaaatggcat
    13921 caagttcaag taatttttct tgagccttgc atttccgaaa aaatcttgct acaatagagc
    13981 cattagaggt gttttgaatc ccacatttta cagaaagtgg cggcgctgag aagtccacaa
    14041 atgtgtcaaa actggttgct aatggatgaa aaattgaaat aaaagtgtct ttttgcttta
    14101 aagacgagag ttgcgggcaa ctgcccgaaa ttgggtggta ccgcggataa acacattcgt
    14161 ccctgtcatg tagatggcag ggcttttctt ttacgtctta gtcaaagggg gttgttatga
    14221 agcaatcttt taacacaagt aaactatatt atggttttcc tgtttttatt ttaggatatc
    14281 aagattagaa ttttggctat aacatcacga cctgtagttc ctcttatagt ctaggagatt
    14341 gggttgtgat tggagtcgtt gcaagagaga atgccgcaga gcagatcaaa cagtatcaaa
    14401 aatttactgt gaatatttct gatgaaactt ctatgcttgc gatggagcag gctggtttta
    14461 tcagtcatca ggagaaattg gaacgtttgg gagtgcatta tgaaatttct gaatgaactc
    14521 agactcctat tttagacgcc tgtccacttg ttttagattg tcgggtagat aggattgttg
    14581 aggaagacgg tatttgccac atctttgcca agattcttga gcgacttgtt gttccagaac
    14641 tcctggatga aaagggacat tttaaaaatc aactgtttgc cccaacctat ttcatgggag
    14701 atggatatca gcgcgtttat cgctatctgg acaagcgtgt agatatgaag ggcagtttca
    14761 tcaaaaaagc gaggaagaag gatggcaaga actgagctgc cagataaaat cgaaacagaa
    14821 cgtctcgttt tacgagtccg tactgtggcg gatgctgagg atatctttga ctatgctagt
    14881 ttgccagagg ttgcctatcc agcaggtttt cctccagtca agaccttgga agatgagatt
    14941 tattatctgg agcacattct tccggagcgt aatcaaaagg aaaatctccc agcaggctac
    15001 gggattgtcg tcaaaggaac ggataagatc gttggctctg tcgatttcaa ccatcgccat
    15061 gaagatgatg tgctggaaat cggctatacc ttacacccag actattgggg gcgaggttat
    15121 gttccagaag cagcgtgtgc cttgattgat ctagctttta aagaacttgg tcttcacaag
    15181 attgaactaa cttgctttgg atataacctt caaagtcaac gagtctcgga aaagcttggc
    15241 tttaccctcg aagctcgcat aagagaccga aaggatgttc aaggaaaccg ctgtgacagt
    15301 ctgatatatg gcttgctgaa gagcgagtgg gaggaataag atgagcgatg taaaagagga
    15361 agtaagctct ctatctgaga agcagttacg ccaaattgat gttgagtatg ctgaattaaa
    15421 tgatagtgat attatcgagc gattagctta tttagaaatt aacaacaatg aaaaacgtat
    15481 tgtcatctct gatattgaac caaccaagga aataatgtca gtatcggacc aaatttttga
    15541 gattcaaaag aattttcaaa aaatcaagaa tatgttcgaa ttgtttattt cagatgtctc
    15601 ggatttttta agtattaaaa ataaacttga gtcaaaggaa ttagaaattg aagaggcaga
    15661 tgtaaatcgt ttcatgattc atttattatc cagtggaaaa ttgtttgtcg attttaacga
    15721 aaaccaaatt aaacaaaaat attccaaaga tagtgaggag tttgattgta tacatggttt
    15781 tgcaagctat cagtatgata ccaattttgc ttatcgattt tgccattctt tgagaaatta
    15841 ttcgcaacat actgacttac caataaatga ggtaaaagct gttagcccag atgatgagac
    15901 tgttataata gatttctata ttgatttaga ttatctttta aattccaact ttaaatggaa
    15961 aaaattgaaa ggggagttga taaaactaaa ccaagaaaca tctaagattg acgctatagc
    16021 tctagtgaaa gaatacttta atgctcttac agagctctat ggtaattata ataagttgtt
    16081 tttaaagtta aaccataata cattagtaga tattaaatca aagttggaat cattaaaatt
    16141 gaaacactct aggtattata tttcaaagat aagcaagtat gatcttaaat ataatcctgg
    16201 aaattatact atgtcaccac ttgcagcatt tgctgaaatt gaagagattt atattgaact
    16261 ttcaaaaatt ggtttggtta aaattgtcaa taaaagtaat taaggagaac acacatgtct
    16321 aaagaacttt catctaaata caatccagcc gaggttgagg ctggtcgtta ccaaaaatgg
    16381 cttgatgccg atgttttcaa gccttcaggc gatcaaaagg ctaagcctta ttcaatcgtt
    16441 attccaccac caaacgttac aggtaaactt caccttggtc acgcttggga tacaactttg
    16501 caagatatta tcatccgtca aaaacgcatg caaggttttg ataccctttg gcttcctggg
    16561 atggaccacg cagggattgc cactcaggct aaggttgagg agcgcttgcg tggtgagggc
    16621 atttcccgct atgaccttgg tcgtgagtct ttcttgacga aagtctggga atggaaagac
    16681 gaatatgcca ctaccatcaa ggaacaatgg ggcaagatgg ggctctctgt agactattct
    16741 cgtgagcgtt tcactcttga cgaaggtttg tcaaaagctg ttcgtaaggt ctttgtgaac
    16801 ctttacaaga aaggctggat ctaccgtggt gagtttatca tcaactggga cccagcagct
    16861 cgcacagccc tttctgatat tgaggtgatt cacaaggatg tggaaggtgc cttctaccac
    16921 atgaattaca tgctggaaga tggttcacgc gcccttgaag ttgctacaac tcgtcctgag
    16981 actatgtttg gggacgttgc ggttgcggtt aatccagaag acccgcgcta caaggacttg
    17041 attggtaaaa acgtcatcct tccaatcgct aataaactca tcccaatcgt tggagatgag
    17101 cacgcagatc ctgagtttgg tactggtgtc gtgaaaatca cacctgccca cgatccaaat
    17161 gacttcttgg ttggccaacg tcataacttg ccacaagtca acgtcatgaa cgacgacgga
    17221 actatgaatg agcttgcctt tgaattttca ggcatggatc gttttgaagc tcgtaaggca
    17281 gtcgttgcta agttggaaga aatcggtgcc cttgtcaaaa tcgaaaaacg tgtccacagt
    17341 gttggtcact cagaacgtac aggtgtcgta gttgagccac gcttgtctac tcaatggttc
    17401 gtcaagatgg accaattggc taagaacgcc attgccaacc aagacacaga ggacaaggtc
    17461 gaattctacc cacctcgttt caacgatacc ttccttcaat ggatggaaaa tgtccacgac
    17521 tgggttatct ctcgtcagct ttggtggggt caccaaatcc ctgcctggta caatgctgat
    17581 ggtgaaatgt atgtcggcga agaagctcca gaaggtgacg gatggactca ggacgaagac
    17641 gtcttggata cttggttcag ttctgccctc tggccatttt caaccatggg ctggcctgaa
    17701 gtcgactcag aagactttaa acgttatttc ccaacttcaa ccttggtaac aggttacgac
    17761 atcatcttct tctgggtgtc tcgtatgatc ttccagtcat tggaattcac aggccgtcaa
    17821 ccattccaaa acgtccttat ccacggtctt attcgtgacg agcaaggacg caagatgtct
    17881 aagtctctcg gtaacgggat tgacccaatg gatgttatcg agaaatacgg tgccgatgcc
    17941 cttcgatggt tcctttcaaa cggttctgcg ccaggacaag acgtgcgttt ctcttatgag
    18001 aaaatggatg cttcatggaa ctttattaac aagatttgga acatttctcg ctatatcctc
    18061 atgaacaatg gaggtttgac gctggatgtg gcgcatgaca atgtcacaaa agttgcaaca
    18121 ggtgaggctg gtaatgtgac ggaccgctgg attctccaca acctcaatga aacgattgga
    18181 aaagcaactg ctaactttga taagtttgag tttggtgttg ctggccacat cctctacaac
    18241 ttcatctggg atgaatttgc ggactggtat gttgagttga ccaaggaagt cctttatagc
    18301 gataatgaag aagataaggt aattactcga tctgttctcc tttacactct ggacaagatc
    18361 cttcgtctcc ttcacccaat catgccattc gtgacagagg aaatctttgg acaaatctca
    18421 gaaggttcta tcgtgacagc tgcataccca actgttaatc tagcctttga agaccttgcg
    18481 gctcacactg gtgtagaaag tctcaaagac ttgatccgtg ccgttcgtaa tgcgcgtgcg
    18541 gaagtaaatg tagcaccaag caaacctatt acaatccttg ttaagactag cgatagtgac
    18601 ttggaagcct tctttaacag caatgtcaac tacatcaaac gctttacaaa tccagaacat
    18661 ttggaaatcg catcaaccat ccctgcacct gaactggcta tgtcaagtgt catcacagga
    18721 gcagaaatct acctgccact ggccgatctc ctcaatgttg aagaagaact agatcgtctc
    18781 gacaaagaac tcgctaaatg gcaaaaagaa ctggacatgg ttggtaagaa actctctaac
    18841 gaacgcttcg tagccaacgc caaaccagaa gtcgtccaaa aagaacgcga caaacaagct
    18901 gactaccaag ccaagtatga tgcgaccgta gcacgtattg atgagatgaa gaaactcgtt
    18961 aaataaacac agaaacacgg tgatgagccg tgtttttttg gtataatgaa atcaatatct
    19021 attgatggag aaagtgatgt ccaaacaccc tcattatgaa ttgttaaatt taattggcta
    19081 cggtcttgcc aagtttgaca agctttttat aaaagaattt caatgctcta gcaagtcgga
    19141 gttttatcgt tatgtggttt ctctgggaat tgctgaaaca actggagttg taaaaaatag
    19201 aatggattta tttgatcctt attttgacaa taatcgaaaa ggttggtggc agaaagctga
    19261 agtttatcgt tttcgtaaag atttaattga tatgatgttt ggaaatgaag atgttcatag
    19321 ttatgctgaa atagttaaaa tgttacttgc cagtgaaggg aagaaaacag gcataaccat
    19381 cgttgaaaaa ccaatagttc gaactaaatt caaacgtcta caggaaacgg gaatggaggc
    19441 tgagaattat tttatccttc attttgataa agaagaaaaa ttccaaggtg gacagttaac
    19501 cgatgcccgt ctttatggtg atggatatga ctttcaggta gatgtccaag agtattctta
    19561 ccttgccgaa gtaaaaggta tccgaaaatc taaggggcgt gtgcgtttaa ctgcaaaaga
    19621 atttgaaaaa gtcaaggagt ttcaatcgga ttttatttta tccttggtca caaatctaga
    19681 tgatattcca aagttagtgt taatcgataa tcctttaaaa cattttgagt ttaaaaagaa
    19741 tattatcaaa aatgaaatca ttgaatatag aagcttagaa gatttgtatt agttcccccc
    19801 ttaacttttc cagttgaaag aacgagaagt cttgacaggt caacgactca atgaactgga
    19861 aatcaacggt attcgtttaa ctaaatttaa aaatggggaa atcggtattg aatttatctg
    19921 gattgatacc gaaaatcccc caagcgatgc catcggctgg gtagcaaaga aataaaagtt
    19981 ttcaaaggta ttgtaacaaa taagggattt tattttcgtg tacaatttca gctattcttg
    20041 ttataatcag cctataggaa tcaaggaggt gactcttatg gctgtttttg tgtctttgga
    20101 tggaattgtg gtagaagtac ttgatgtctt ttcttctttt gatggggata gtgagttttt
    20161 cttgtgtaaa cgtcttaaag acaagagtca gtttgttatg gaacgctctc agttcgagga
    20221 gatgttccaa cttcaaagta gtcgcttgac gacgcaagaa aaattacaat tgtttacctc
    20281 tgtgtttgct ggccgttatg atgtttatgc taagagtttt atcaatgatc aagggaaaat
    20341 tcagtatttt ccttcctatg attatggttg gaagcagttg ctacctgaaa aacggagttt
    20401 ccagacattg acggattccg ttttgaaatc tcattttcgt ggggaggcag ctatcggtat
    20461 ctttcctatg cacttagatg atagctgtta ttttttggta ctggatttgg atgaaggaga
    20521 ttggaaagaa gctggtttaa ccattcgaag aatagccagg gaacgccaga tggaagccca
    20581 tttagagatt tctcgttcgg gttacggact ccatatttgg ttcttctttg aggaagcgat
    20641 tctgagtcga aaggctcgcc tgtttggaaa gaaactatta gaattggcaa tgcaggaaag
    20701 tatgcaactg tcctttgatt cttttgatcg catgtttcca aatcaggatg tccttcctaa
    20761 ggggggattt ggaaatttga ttgccttgcc ttttcaagga gaagcttacc atcaagggcg
    20821 aacggtcttt gtggatgaac agtttcagcc ttatgaagac caatggaggt atctacaaga
    20881 aattcagagg atttcaactg ctaaagtggc actgttaatc caagaggagt taggcaagca
    20941 agaattggat aaggagttga aggtcgtttt atccaatatg atccaacttg aaaaatcgtc
    21001 tgtgacatcc aaggcacttt tttcttgaaa aatatggctt ccttttctaa tcccgaattt
    21061 tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt agaaatcgat
    21121 ttgactttcc tgatcgattt gtcctgttat tatttcattt tactatattt aaagcaggct
    21181 atgcgacagc caacctatca aattcctgag agaatgtatt tatttggaga atccgatcat
    21241 tatttatggt tgccaagagg tttgctgtat ccattgcaag ataaatttaa gcaggtatct
    21301 gtggaagata ggagaaaggt acaaaggtct attagcgtgg aatttaaggg agaactcact
    21361 tttgagcaag agttagccct gtcagatatg acttctaaag aaaatggttt acttcatgcg
    21421 gagactggtt ttgggaagac cgttttaggt gctgctctta tctctgaacg gaaaacaaaa
    21481 acaattattc tagtccataa taagcaactc ttagaccaat ggctagatcg cttaaactgc
    21541 tttttgactt tcgaagagga ggaggctatc cgttatacgg catcaggtcg tgaaaaggta
    21601 atcggctatg ttgggcagta cggtgggact aagaaatggc tgagtaaact ggttgatgtc
    21661 gttatgattc aatctctatt taagttggaa aatagtcaaa gtcttttgga tgagtatgag
    21721 atgatgattg tggatgagtg tcatcatgtc tctgccttga tgtttgaaaa agttgttgct
    21781 cagtttagag ggaagtatct ttacggtttg acggctacgc ctgagcgtaa gaatggtcat
    21841 gagcctattg tttttcagag aattggtgag atactccata ctgctgataa gagggaaacg
    21901 gattttaaac ggcaattgca attaagattc acttcttttg gtcatttgga aattgaaaag
    21961 accaaagcaa gtaattttat acagcttagt gattggattg ctactgactc agtgaggaat
    22021 cagatgattc tcaaggatat tctagcccaa gtggcagaag gacggaatat cttggtttta
    22081 gttaatcgaa ttcaacagat agatgtcttt gaaaaattat tgaaagagaa agaggttgat
    22141 gactgttaca ttattagcgg aaaaaccaaa gtccgagaga gaacgagttt actggagacg
    22201 ttagaacagt tagataaagg gtttgttttg ttgtctactg gaaaatacat tggcgaaggt
    22261 tttgacttac ctcagttgga cacgcttatc ttggcagcac ccttttcttg gaaaaataat
    22321 ttgattcagt atgcaggttg gattcataga aactacaagg ataagtcttt ggtgcgtatt
    22381 ttcgattatg tggatattca tgttccttat ttagaaaaga tgtttcagaa acgacaagta
    22441 gcttatcgaa agatggatta tcgtgccatt gagggtgagg agaaacaatt cgtttatgtt
    22501 gatagtagat atgagaaggt gttgagagag gacttagcag gggaaagaca ggaatgtctg
    22561 cttattttac cttatgtgca ccagacaaaa ctgatgaatt ttctaaaaga atttaggatt
    22621 agtcaaattg agatatgtat accagagacg gttgcaaata aagcatggct agaccagttg
    22681 aagagccaga aaattaaagt gtcttttact caatcaaaaa tagtaacgcc tattcttttg
    22741 gtgaataaga ctattgtttg gtatggtgca atgccattat tagggaaggt agatgagatg
    22801 accatattac gtttggaatc agctagtata gtttctgaac tagtggcagg tttacgatag
    22861 agaaaatttt taaaaatttc tatgtatgat tttcatttct tt
//
LOCUS       DAVLZG010000027        22375 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLZG010000027 DAVLZG010000000
VERSION     DAVLZG010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.027"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..617)
                     /locus_tag="VYO72_001080"
     CDS             complement(<1..617)
                     /locus_tag="VYO72_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1707469.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLEN"
     gene            complement(726..1244)
                     /locus_tag="VYO72_001081"
     CDS             complement(726..1244)
                     /locus_tag="VYO72_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1707470.1"
                     /translation="MRTYENKEELKAEIEKTFEKYISEFDNIPENLKDKRVDEVDRTP
                     AENFAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="VYO72_001082"
     CDS             complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="VYO72_001082"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1707471.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="VYO72_001083"
     CDS             complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="VYO72_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1707472.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2700..3590)
                     /locus_tag="VYO72_001084"
     CDS             complement(2700..3590)
                     /locus_tag="VYO72_001084"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1707473.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3587..4225)
                     /locus_tag="VYO72_001085"
     CDS             complement(3587..4225)
                     /locus_tag="VYO72_001085"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1707474.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4445..5242)
                     /gene="proC"
                     /locus_tag="VYO72_001086"
     CDS             complement(4445..5242)
                     /gene="proC"
                     /locus_tag="VYO72_001086"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1707475.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(5246..6508)
                     /locus_tag="VYO72_001087"
     CDS             complement(5246..6508)
                     /locus_tag="VYO72_001087"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1707476.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASFLPRLEQ
                     VLVAERKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6518..7648)
                     /locus_tag="VYO72_001088"
     CDS             complement(6518..7648)
                     /locus_tag="VYO72_001088"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1707477.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7728..9605)
                     /gene="cbpE"
                     /locus_tag="VYO72_001089"
                     /gene_synonym="pce"
     CDS             complement(7728..9605)
                     /gene="cbpE"
                     /locus_tag="VYO72_001089"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1707478.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSLISVVKVNG
                     KKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTS
                     DSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPSFQ
                     AGWHKSVYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFYLT
                     DSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQWYY
                     FAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKANDW
                     YFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKSAT
                     IKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSESE
                     Q"
     gene            complement(9608..10495)
                     /locus_tag="VYO72_001090"
     CDS             complement(9608..10495)
                     /locus_tag="VYO72_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1707479.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLSLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10485..10946)
                     /locus_tag="VYO72_001091"
     CDS             complement(10485..10946)
                     /locus_tag="VYO72_001091"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1707480.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10943..11851)
                     /locus_tag="VYO72_001092"
     CDS             complement(10943..11851)
                     /locus_tag="VYO72_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1707481.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11844..12050
                     /locus_tag="VYO72_001093"
     CDS             11844..12050
                     /locus_tag="VYO72_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707482.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLHYLPFSR
                     QSYFQNQFKKISGYTPLQYRKEKR"
     gene            complement(12102..12773)
                     /locus_tag="VYO72_001094"
     CDS             complement(12102..12773)
                     /locus_tag="VYO72_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707483.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12827..13048)
                     /locus_tag="VYO72_001095"
     CDS             complement(12827..13048)
                     /locus_tag="VYO72_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1707484.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13319..14128
                     /locus_tag="VYO72_001096"
     CDS             13319..14128
                     /locus_tag="VYO72_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1707485.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     NVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14309..15184)
                     /gene="aguB"
                     /locus_tag="VYO72_001097"
     CDS             complement(14309..15184)
                     /gene="aguB"
                     /locus_tag="VYO72_001097"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1707486.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15194..16279)
                     /gene="aguA"
                     /locus_tag="VYO72_001098"
     CDS             complement(15194..16279)
                     /gene="aguA"
                     /locus_tag="VYO72_001098"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1707487.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16276..17403)
                     /gene="nspC"
                     /locus_tag="VYO72_001099"
     CDS             complement(16276..17403)
                     /gene="nspC"
                     /locus_tag="VYO72_001099"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1707488.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17403..18662)
                     /locus_tag="VYO72_001100"
     CDS             complement(17403..18662)
                     /locus_tag="VYO72_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1707489.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18659..19519)
                     /gene="speE"
                     /locus_tag="VYO72_001101"
     CDS             complement(18659..19519)
                     /gene="speE"
                     /locus_tag="VYO72_001101"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1707490.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDREGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            complement(19550..19687)
                     /locus_tag="VYO72_001102"
     CDS             complement(19550..19687)
                     /locus_tag="VYO72_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707491.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            19774..20490
                     /locus_tag="VYO72_001103"
     CDS             19774..20490
                     /locus_tag="VYO72_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV1707492.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQ
                     IEIRNSLDKTIDFSYSLSFS"
     gene            complement(20456..21931)
                     /locus_tag="VYO72_001104"
     CDS             complement(20456..21931)
                     /locus_tag="VYO72_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1707493.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVVELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         6485 a         5172 c         3993 g         6725 t
ORIGIN      
        1 taattctcaa gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa
       61 aacacatttt gaaatgttcc aagtccgttt tcaccaaagc tatattctct cttactatac
      121 ttactcttat tattctctat atagttagag tcaaggttct taacctcttg aagttcattt
      181 tctttacttc tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag
      241 tcattttctt ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta
      301 ccaagtccaa gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct
      361 aatgttttta tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta
      421 aaatagataa atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc
      481 cgtttaagaa gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct
      541 ctatcaacta atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa
      601 aaatattcaa agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg
      661 atagtttttc ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat
      721 ataatttata atactatctt cttccatttt ctgatttttg ttctgaaagt tccaaaaggt
      781 gcaaccgtat ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca
      841 tcagcccact ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt
      901 gcagagatag aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga
      961 gcgtaggtat ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc
     1021 gatggtgttt ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg
     1081 gtccagccaa cctgataagc aaagttttct gctggagttc tatcaacttc atcaactctc
     1141 ttatctttta aattttctgg aatattatca aattctgaaa tatatttctc aaatgttttc
     1201 tctatctcag cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc
     1261 tgatttatca atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaggaac
     1321 gctataactg ctgctccaac catcggtatt ccgtatgggc ttaataaaaa acttaatacc
     1381 aaagcttcta taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa
     1441 acagacagaa ttattacatc ctgtctccct ttattgtttt tcttcccagt cgtggtaggc
     1501 agcgtagagc tgacttttat tccactggta aatcttagcg acttccttga tagcttggtt
     1561 tttcttcaca ccttgctgga tgcgggtttg aatttctacg aacaagtctt cctcgtcctt
     1621 ttcctccaca ccctgactgg caccctcaac aatgagaaga cattcgccct tgagtggcgt
     1681 ttcagcaatg ctttctaata actcagagat agtacctcgt tggtattctt catagatttt
     1741 ggtcaattcc ctgaccaaga caactgagcg gtcaccgtag acttctaaca tattttccaa
     1801 cgtgtctgct acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt
     1861 caagccaaaa aattgcttct gctgacctga ttttctcggt aaaaaaccgt aaaagatatg
     1921 tggctgtggc gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg cacctggaac
     1981 tgtcacaact gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga
     2041 aatgctaggc aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc
     2101 aatcaaatca ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga
     2161 aatgtcaaaa tgcttgagca aaagacctgt attgcgcgta tcctcagcag caatccaatc
     2221 tacttctttc aaggtctgga tagctcgaaa ggtcatatca tctagattgc caatcggcgt
     2281 tgccactaga tacagcttgc catagggaga ctgcccctta aaactttttt gaatctgcat
     2341 gcctactccc tgtatagcaa ctcgtcacaa aacatacatt cctcgtcctg ctctcgacgt
     2401 tgtccataaa aatcattaca tacgtgaaat ccatcacggt aaatgcgacg gacactttca
     2461 cgaacatgct tggccttgac aggagcatct gcttccacct cacccaagcg ttctcgcaac
     2521 ttactatttt ccaagcgaag agctgtattt tcctctacca ggctcttgag atttttcttg
     2581 atggcttcca catcggctaa ggttaccaat aattgttggg aaaaatcatc cagcgcgtca
     2641 aataattctt ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt
     2701 tatatttctt tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac
     2761 atttttctag cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc
     2821 tgcccacaga gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc
     2881 aagttggcta atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc
     2941 agcaggcgtt cactttcatc gaccaaggtc caaaaacttg cctgatgtgc caacttttct
     3001 gcttcagctc gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc
     3061 atttgttcta agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc
     3121 cgacttcgga ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact
     3181 tcactctggg gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta
     3241 tccgcttgct cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt
     3301 cccaccaatt cccgaatgcg ttctgtcttg atgacctgat tgactggctt aatcaaggtg
     3361 acatctggaa actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag
     3421 acgccaactt tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt
     3481 ccaaagaaac ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca
     3541 aaacggtcaa actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc
     3601 ccattccgtc aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag
     3661 catcaatctt gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa
     3721 cttttttatg caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag
     3781 cagcaatacg agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt
     3841 tgaggccatc tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac
     3901 caaatccctg ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag
     3961 cttcaagggc tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa
     4021 gtagctctgt tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct
     4081 tctccccaat caagactccg ccaggttcac gggtcgtcaa cacctctact cctttttcct
     4141 ctaaaattgg tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa
     4201 gagagactaa aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta
     4261 tcaaaaaaat aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat
     4321 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
     4381 cgcagtttga atttgatttt cgaagagtat caaccaccat aaaagaggca gataaaacta
     4441 cctcttattt acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgacta
     4501 tgcctcgaaa agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac
     4561 tacaaacttg atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag
     4621 ctcctaccac agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa
     4681 cacctgcatc tgccaaagcc tcaataaaga gatagacaaa ggctggtcca cagcctgcaa
     4741 gacctgtcgc tgcattgatt aagctttctc ctaattcaac caagagacca gccttggata
     4801 aaagctgaca aaagagctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa
     4861 tcactccttg cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttgac
     4921 ttgggataag acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa
     4981 gactttctct tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag
     5041 gcttaactcc tagaaaaatc acatctgctt ctgcaaacat ttcttcattg ctggaagcct
     5101 gaccaccaaa gtctgcaatg aaagcatcta ccttagcttg actacgattg gcaaggagaa
     5161 tctcatctga cgtcctagtc tgcaagacag attttgccaa gctagcaccc atattcccca
     5221 aaccgataaa tccaatcttc atctcttact cccttatctg cccatcacca gtgaccacat
     5281 acttgtagct agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag
     5341 aaatccccat ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat
     5401 taacatacac cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt
     5461 ccgtcacaat ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt
     5521 ctaaactgct cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt
     5581 gtgcttgagc agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa
     5641 ttggttccag tccagcttcc ttacgctctg caaccaacac ttgctccaag cgaggaagga
     5701 agcttgctgc cttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac
     5761 gactggtttt agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca
     5821 catagacatg gacaatccca gtccctgtct cgataacagg tacaatcgca ttctcaacca
     5881 ctgcattgat caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct
     5941 tcatcatagc ataactactt tcacggctag tatcctccac cagttgaatc acatttggat
     6001 gaatagtagt cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat
     6061 aggcatcctt accactacga agaacaaccg catttccact cttaagagtc aaagcagccg
     6121 catcagacgt cacatttgga cggctttcat agataatacc gatgacaccc atagctacac
     6181 gtttttttgt gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg
     6241 gatctggtaa ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat
     6301 ccaaataaag acgatccaac atcacatctg agattttccc cttagccgct gccatatcga
     6361 gggcattagc cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca
     6421 aggcttggtt tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct
     6481 gttcaaattg ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt
     6541 ggatttcagg agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt
     6601 gagaacgcaa catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg
     6661 attttccact ttccttgtca aatactgtca cgatatcacc gtaagaaaag actccttctg
     6721 cttcaacgat accagataag agaagactct ttccatgttg agagagagct tccgcagccc
     6781 ctttatcaac ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg
     6841 tacgaagccc cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct
     6901 caatcatgga atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg
     6961 cgatagttgc agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc
     7021 caccagccat atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc
     7081 ttggatctga attaggattt ccagtataga gaccgtccac atctgtcaag agaaccaaaa
     7141 ggtctgcttg gaccatcgcc gctacttggg cacttagagt gtcattgtcc ccaaccttga
     7201 cctcatcaat aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagta
     7261 aaaccgacaa agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg
     7321 tcagcaagat ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca
     7381 acaaaagtcc ctgccctacc gctgctgaag cctgtttatc agcaatctta gtcggacgct
     7441 ttttaaatcc taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact
     7501 catgaccagc ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg
     7561 ataaacttcc atcctcattt gtcagagaag aagtacccac cttaaagaca atccgtttgt
     7621 atttcatagt ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat
     7681 agaaaagagt tgataggaaa aagaaggccc taaaaccttc ttttctacta ctgttctgat
     7741 tccgatttgt ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta
     7801 gttgaagaat ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc
     7861 actacttctt tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc
     7921 tcgatcgaaa catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc
     7981 ttaccattca caagtaattg accattttct ttcaagaagt accatttatc cttgtccttg
     8041 atccaaccca cagctcgtga accgtctgtc ttgtagaaat accaatcatt tgccttttta
     8101 tgccagcctt gcttcatagc tcctgaatct tccagataat aatgttgacc agcaacttct
     8161 atctcacctg tcttcatgac accagtagaa tccatatagt accaggtttc tttatctttt
     8221 acccagccca ttttcatttc ccctgatgga gcaaagtaat accattgccc catatattga
     8281 agccatcctg tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga
     8341 acccaaccaa tttccatctg attttctttg ttaaaataat accagattcc atcaattttc
     8401 ttccaatttt tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt
     8461 ttccattgat tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt
     8521 tcattccaac cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca
     8581 tatacactct tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata
     8641 ttgacaaaac cgtcttttcg aatatcaaaa actgtcgcat catagtcttt gctggctgcg
     8701 ttgattctct caattcctcg ttctttgagc caattaacat actcactatc aacaccattt
     8761 ttccaaggta gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa
     8821 tccttggtat ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt
     8881 ccaatgagag gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg
     8941 taaattttct tgccattgac tttcaccacg ctaatcaagg aattgtcatc ccaaattttc
     9001 tttaattcac ccgatgaatc agtttcattt tcataattat agagctgaat atccatgtcc
     9061 ccaaactgaa aatgagcatc cccttgtgtg atattttgaa taactgaaac acctgtttct
     9121 gcagcagtct gtaaaacctt atcatagcca tacagattat cccatagacg ttcagaatta
     9181 gtaatacgac tatcactata tttcttaaga tagactcggt caactggata ggtagacagt
     9241 aattcatcaa catttccaat atgatcactg tgggtatggg tcaccaaaat aaaatcaagt
     9301 ttttggacac ccaattcctt caaacgacga aagacacggt ctgttagaac atgcttataa
     9361 gacgtttcaa ttccttctct ccatggatag cgagaatcac ttccatctgg gaaatcataa
     9421 tcttctcctg tatccaccat ggcaaaatgt ccattgcttt caagaataat cgcatcactg
     9481 ccaccttctt gaacattgat aaagtggatt ttatttcctg aactttcttg agcctgaaca
     9541 ttcccatacc atgacaaacc taaaaaagcg cctacaagtg ctaaactagt taatttcttt
     9601 ttcattctta ctttctcaat ctctccaagg tttccttaaa aatctctggg atatctgctt
     9661 taaattccaa ggtcttacct gttctcggat gagtaaaacc taaagtcttg gcatgaagaa
     9721 attgtccatg tcctttcaaa gtcttgcgag gaccatagac ctcatcacca gcgactggat
     9781 ggccgatata agccatgtgg acacggattt gatgagtgcg ccctgtctcc agttgcaact
     9841 ctactaagct ataatcgcca aagcgttcca agacgtgaaa acgcgtcact gcaggcttcc
     9901 ctttagcagt tacagcctgt ttcttacggt ctttttcact ccggccaatc ggcgcttcaa
     9961 ttacaccacg atcattaggc agatttccat gaacaatcgc ccaatatttg cggagagact
    10021 ttttatcctt gagttcttgg gcaagtgcta gatgcgcatc atcgttttta gcaatcatga
    10081 gaagacctga cgtatcctta tcaatacggt gaacaatccc tggacgcaga accccattga
    10141 tacccgacaa gtccttaata tgatacatga gggcatttac tagggttcca ctggtatgac
    10201 cagcactcgg gtgcacaacc attccctgag gtttgttaac gacagccaca tcctcatctt
    10261 ggtagactat ttctagcgaa agatcctcag ccacatactc taatacctct ggttctggca
    10321 catggtaagt gacgacatca ccctcttgga ctgtgtattt agctttcttg acttgaccat
    10381 tgaccaagac ctggcctgat ttaatttgtt cattcgcgag actacgtgat aattctgaca
    10441 aatctgacaa agccttatcc aaacgcagac caccagtttc aattttaatt tccatttatt
    10501 tcctctttta gcattgcaat caataaaata atcactccaa ccgtcagata gctatctgcc
    10561 acattgaaaa ttgcaaagtt gataaagtca aggtggaaca tatccacaac aaagccctga
    10621 ctgaccctgt caataaagtt tccaagacca cccgcgatta ttagagtcaa acccaagacc
    10681 atccagaatg agtcctccat gtgtttatgt aaataccaaa tggcacctat cacgacaacc
    10741 agagtaatga cagcgaataa cagctgctga tcttgtaaga tagaaaaggc tgcacctcga
    10801 ttttgcaggt aggtcaagct aacgaaattg ggaatccagg agcgcacttc acccagtgga
    10861 atctgctgga cgatatagga tttgaccaac tgatccagcc caattaaaag cagtacaatg
    10921 actgccacta ttgctctttt tttcatgatt tcctcttttg atcaaaatat tcttgcatga
    10981 cttctacgaa gagagtccca gcttgactaa gctccacttc ttcacgttta acatagacca
    11041 tgcggttatc taggttatcc ttgagacgaa taactgtaat gccattaaca ctgtcactat
    11101 ctaaaaatcc agaacctgtc gcataggcgt ccgtccgctc caaaatacca ttcaaggtgg
    11161 cacggtctgt cacattaaac atctgtgagc tagcgctggt atcgacaaag ttctctgaat
    11221 aataaaggta ctcgtctttc tcttgagtga aacgaaccgt tggtaaatcc gctaaatcct
    11281 ccatgactaa ttcctctttc tgggctaaag gatgaccctc acagagataa atatgggtat
    11341 ggaaaggaat caattcgatg acctccagac ctaacttttc aacccgttgc ataatcccct
    11401 ttttattttg attgttgagg tagataatcc caatctcact atgcccttgc gccacttcat
    11461 ctaatatttg aacagtagtt gattcaaaaa tacggaagtt cttatagtca ggatagcgct
    11521 ctgaaaaggc cgtaatagtt ggtggtaaga agtcatagtg ctggctagca acggaaaatt
    11581 catctttttc ttcttcagga ttggcatact gattttgaaa aatatcaaat cctttaacca
    11641 attcttgcgc tttttcataa aattccatcc cacgacgggt caagaaagtc cctgagctgg
    11701 tccgacggaa aatcttaaag cccaactctt tttccaaatc acgaacagaa atagacagac
    11761 tcggctgact aacatacatc ttttcagcag cttcacgaaa agtaccacta ttggcaatag
    11821 ccacaacata gcgtaattgt tgaatgttca tcttctaccc ccaacttctt tatcttttca
    11881 ttataccata ttttagaagt tttccaaaaa ggaaaaaaga acatcctatt cttcttaact
    11941 atcttcacta tcttcactat ctgcctttct cacgccaatc ttattttcaa aatcaattca
    12001 aaaaaataag tggctacaca ccacttcagt atcggaaaga aaaacgttga ctatttgtga
    12061 aaaaagaaaa tgccggaaaa ttccgacatt tttttagtaa gctaacttcc tgaaaatagg
    12121 agtaaccaaa catcccagaa ggcagtgata ttgatgagaa tatgaactag tattggatag
    12181 tagagatttt tagtcatgcg atacaataga gctaaaatca gacctccact agcataaatg
    12241 aaaaaagcaa gaggagttaa agcaaaattg atatgaatat aaccgaaaat aatagcagaa
    12301 agcaaaacat ctccgtacca aggtgagttt ttgaaaaagg ttgtcataag cacacctcga
    12361 taaatcaatt cctcagcaat aggggcgatg aagcaaacga tgagcaagaa ataagggaac
    12421 tcctgtctcc ccatcatttc taccgtttca ttcaaagaaa tctgatttga agacagggat
    12481 atgaaatacg aaaagaggaa gtcagacata tatgaaatga tgtagcccag taaaaggtag
    12541 atgaagtacc tcagctgcca cttgaaatga aaaattttct ttcctgcaaa aaccagtaga
    12601 tagatgaccg ctaagaaaag aactccgctc tccatcaaaa gcagaatctg aaaaaattca
    12661 cgacttgctg gtagataggg ctttgcgagg tgattgaaaa ctctccaaaa ccaagttgat
    12721 ttgtaaaaaa ttaaggacaa tgctagtaaa atttgaatag cccgtttttt catattaaat
    12781 cctctgtttt ctccccttgt ttcttcatat tcctaataaa ttttacttaa aatctcgcag
    12841 cacttccttt gcaaagatga ttgcctcctc caatatatcc taaatcatag gtgcctctgg
    12901 gacaaaatcc atgaaccggc agagttaata ctggttctat ttcccaatcg tacctaccat
    12961 taggattttt accataggga tctgctccac cttgtatcag ctctaattct tcatttgtta
    13021 gatttatatt ttttgtcatt aaaatcatga tatatttcct ccattattct tcagattagt
    13081 tgagtaatct actactcata cctacttaca aaaaaactat tttaagctag tttttttatg
    13141 cttgtctagt tgcaatattg acaagtttag tatatcatat ctttgccaaa tatcctcttc
    13201 aaatcttgaa ttgtcatcga aacgtcctaa actgcaaaat caattagtct caagctttct
    13261 atcaatttct tctccaaaat atgctataat aatagcaaaa gataaagaag gaagacctat
    13321 gattaaacta ctagccttgg atatggacgg caccctcctc aatgaagcca aggaaatccc
    13381 acaagctcac attactgcta ttcacaaagc cattgaaaaa ggtgtcaaac tggttctctg
    13441 tacgggtcgc ccccttttcg gtgtcctccc ctactacaaa aaactggggc ttgacctcca
    13501 gaacgaatat gttattgtta acaacggttg ttcaactcac caaaccagtg attggggtct
    13561 agttgactgg aaagaactga gtccagctga catcgaatac ctctatgacc ttgctgaaaa
    13621 gagtaatgtt cagttgacac tttttgacga gtcacattat tttgttctcg gtggcaagcc
    13681 caatcaagtt attgaaaatg atgctaaact agtattttca gacctgactg aaatttctct
    13741 tgaggaagcg actagtggaa agttccggat gttccaaggt atgtttttag gaacaaaaga
    13801 acaaacagac gattttgagc agcgttttgc tgaagagctt tgccaacgat tcagtggagt
    13861 tcgttcgcag cctgtcattt atgaagcaat gccacttgga acgacaaagg ctactgctct
    13921 ttcacgacta gctgagattt tgaagattga ttcctcagag attatggcca tgggcgatgc
    13981 taataacgat atcgaaatgc tccagtttgc agggcttggg attgcaatgg gaaatgccag
    14041 cgattatgtc aaatctcttg cggatgccgt tacctcaagc aacgaagaag acggcgttgc
    14101 gcgtgctatt gagaaatata ttctataaaa aagaaaagca aatagacaga agttactgct
    14161 atttgctttt ttgctaatat tttaaaatac ggactaatca atagacaaga atagcgaatc
    14221 ataaaaatcg atttactaga tgccatagta tcttatagtt gctaataaga agttagtcta
    14281 gcagaatgaa tctctcattt ctcccacact aatctgtaat ttgtctatac atttctggtc
    14341 ttctatctcg aaacaagccc cagtttaggc gttcactcgc tcccttgtct aggtcataag
    14401 tagctaacag aacagcttct tcttgtcttt cagctcgttc tagaatagct cctgtttcat
    14461 ccgtcataaa ggaggaaccg tagaagtcaa gactggaact ctgtccgcca ttttcctcac
    14521 taggagtaac ctcctctaaa ccataacgat tggctgcgat gactggaaca atattcgctg
    14581 ctgcgtgccc ttgcatagta cgttgccagt gaccacaact atctgtatcc aaaatcggct
    14641 ctgaaccgat ggctgttgga taaaagagca attctgcccc attcagagca agacagcggg
    14701 ctgtttcggg gaaccattga tcccaacaga taccgatacc aatcttagca tagcgagtat
    14761 tccagacctt gaaaccagtg ttaccaggcg tgaaatagaa tttttcttga taataatggt
    14821 catctggtat gtgggtcttt cgataaacgc ccagcacttc cccatctgca tcaataacgg
    14881 caatagagtt atacaagaca ttaccatctt tttcatagaa actgattggt aaaacaactt
    14941 gtagttcctt agcaatcacc ttaaaatgct gaatggcagt attttccgct acagattggg
    15001 catactggta gtagtcatac tgacgttcct gacagaaata gggatgttca aacaactcgg
    15061 gcaagagaat aatttgggct ccttgctcag cagcctgacg tactaaacgc tctgcggttt
    15121 ggatatttgt tgccacatcc ttagcgcatt gcatctgaat ggttgcaact cttacatttc
    15181 tcatcttttt ctcctattct ggaatttgtt gggtgataca gtggatattg ccaccaccta
    15241 agagaatatc tctggctggt attccgacaa ctttacggtc tgggaaacac ttgctgagga
    15301 tatctaaggc cacttggtcg tttacatcct caaactgtgg aaccaagaca gccttgttgg
    15361 cgatataaaa gtttacgtag gaagctgcta gtcgttcacc tgcgtatcgc ttttcttctc
    15421 cttcttcata gatgtagcct ggcaaatctt cttctgtcac aacttgtcga actgcaggga
    15481 taggcaattt atgaatggtg aagtgacaac cttttgcatc tgtttcctgt tctaagagtt
    15541 cgagatctgc ttttgacatg gcatactggg gatcattttc gtcatctgtc caagctaaaa
    15601 caacctcagc aggaccaaca aaggcagcaa cattatcgac gtgttcattg gtttcatcct
    15661 gataaatacc ataaggaagc caaataactt tttcagcacc aagactttct aataatgtgt
    15721 tttcaatctc ctctttagtc aggttaggat tgcgaccagg actaagcaag caactttcag
    15781 ttacgagaat agttccttga ccatcgctat ggattgcgcc tccttccagt acaaaaggtt
    15841 tagcatcata gacaggcttt tccaaggcct cagcaaaacg actggctact tggtcatcct
    15901 cttcataatc ttgataaaga ccatcatagg tgcctcccca agcattgaag gcccaatcca
    15961 cggctaattt cttaccttta tcattgacga gaatggttgg gccagtatca cgcgcccagg
    16021 catcattggt gggaatgtct aaataaacaa ccttgtctcc aagataggat tgggcttcag
    16081 atagataggc ctgctccacc aaaagataga ctctttcccc ttctgctatg gtctcgatga
    16141 tctgagtaaa tgatctttta gcagcctttc cttgaaaagg ccatgatcct ggtcgagtcg
    16201 gccatatcat gagggtacca tgatggggtt cgtactctgc tggcatgtga tagcctaatt
    16261 tttttggact gtccatcatg ataatctccc tttaaagtct tgatagccaa aagctttgag
    16321 taagctacag tctccctgtt cgtccatgag atagagactt ggcaatccaa taccattaaa
    16381 ggtattattt ttgacaaaag aataaatggc catgtcttga aaataaagtc tgtctccgat
    16441 ttggactgga ttttcaaaac tataatcacc aatcacatcg cccgtcagac aggtattaga
    16501 agaaagtctg taggtatggg ctttttcctg tgcctcaaag ccatttctca aaggtggacg
    16561 atagggcatc tcaagtacat caggcatatg gcaggtcgca gaggcgtcta aaaccaagat
    16621 ttccatacca ttttctacaa tatctaatac ctcagttgct aaataacccg cattaagcgc
    16681 aatggcttca ccaggctcga tatagatttc aagattgtaa gtttttcgga tacgcttgat
    16741 ttctgaaatc agcaaatcca catcgtaacc ttctcttgta atatgatgac caccacccat
    16801 attgagccat tttacctcat gtaagtaggg accaaactgt tcttctactg ctttcaaagt
    16861 tgtttgtaaa tcatctgctc cctgctcgca aagggtatga aaatgaagtc cgtcaaccaa
    16921 atctagcaaa tcactcggaa tcttgtctat agtaactcca aagcgagaac caggtgcaca
    16981 agggtcatag agcgcgtgat ctccttgagt tgaacactga gggttgaggc gcaaaccaac
    17041 actgacacca gcctctcgac aacgagcccc atgcttacgc aactgtctct ctgagttaaa
    17101 gacgatatgg tctgttatcc caagcaattc ctccatgtcc tcatccttga aagctggtgc
    17161 aaaaacatgg acttcaccag gaaattcttc ccttgccaat ttggcctcat agagtccact
    17221 agctgtcgta cctgatagat actggctaat caagggataa gttttgtaga gggaatatgc
    17281 cttctgggca agcaagacct tgcaaccggc ctcttcttgt acatattgta gaatgcggca
    17341 attagcttct aacttggcca agtcaataac ataggctggt gttggtactt gttctaactt
    17401 cattagtcca ccatttgtgg attttcaacc acaacccatg gcaaaccata ctcattcaaa
    17461 gcttccatga atggatctgg atctaactcc tcaaggttat acactccagc ttgtttccaa
    17521 gttccgttca tgactaattt tgtcccaatc atggctggaa ctcctgtcgt ataagaaata
    17581 gcttgcgaac caacctctgc gtaacattcc tgatggtcgc agacattgta gatatagata
    17641 gtctttttga caccgtcttt gacacctgta aagatacatc caatattggt tttacctaca
    17701 gtacgtggac caaggctagc aggatctgga agcaaggctt tcaaaaattg aattggaaca
    17761 atttcttggc cgttaaagtt aatggtatcc gtacgaagga gtccaacatt ttcaagacat
    17821 ttcatgtgcg tcaagtaaga ttgaccaaaa gtcataaaga aacgaatgcg tttgactcca
    17881 ggaatgttct tggccagcga ttcgatttct tcatggtgaa ggagatacat atctttttgt
    17941 ccaacttgag ggaaatcata ctcacgcttg atagacatag cttcgacttc gacccatttc
    18001 ccatcttccc agtaagaacc tggcgcagaa acctcacgga gattaatttc tggattaaag
    18061 ttggttgcaa atggataacc gtggtcaccg ccattacagt ctaaaatgtc gatataatgg
    18121 atttcatcaa aatagtgttt gagggcataa gctgaaaaga cactagttac acctgggtca
    18181 aaaccagaac caagaagagc agtcaagcct gcttctttga atttctcttg ataagcccac
    18241 tgccatgagt agtcaaagta ggctgtaaaa ccaagttcct tacaacgttt ttcgtagata
    18301 gcacgccact cagggtcttc tgtgtcttct gcttcgtagt tggctgtatc gatatagtga
    18361 acacctgttg ccaaacaagc atccataatg gttaaatctt gataaggcag agctacattc
    18421 aaaacagctt ctggtttgta gctttcaatc agggcaatca cttcttcaac cttgtcagca
    18481 tcaagtgctg cagtttcaat tttagtactt gttttgcctt ctagcttcgc tttcaagtca
    18541 tcgcattttg acttggtacg gctagcaatc ataatctctg taaatgtttc gctatcttga
    18601 caaatctttg aaatagcaac ttgggcaacg cccccacaac caataactag taaacgactc
    18661 atttttttcc ttcctcttct tctaaaatgt cctcaacata cttgggcaac ataaaggatc
    18721 ccacgtgtaa gtttgcagtg tagtattctg tgaaaagctg gcgttttttc caaccttccc
    18781 tgtcaaaatc tttgacaggg tggtattttt tcgatgcaaa tccaaacaac caatagccag
    18841 ctgggctagt tggaatatgg gcctgataaa cccgactgat tggaaaggct tgattgacct
    18901 tgcggtgcat gcttcggcag gccgactcat cctcgtcaaa gaagggactc ccatgctggt
    18961 aaatcatgat gccgtcttcc ttcagagctc gataactatt gccgtagaat tctttggtaa
    19021 agagtccttc cgtatggcca aatggatctg tcgcatcgtt gatgataata tcgtaatcat
    19081 cttcgcagtt tcgcaaaaag cgtagcccat tttggtagta aatggtaaca cgaggatcat
    19141 ctagccctgc agcaaagtct gggaaatact cacgacagac ctcgaccaac atttcatccg
    19201 gttccacgat atcgatttgt tccagttcag gatagagtgt taatacttgg gcaacaccgc
    19261 cgtcaccacc cccaataacc aatactttct ttggatttgg gtggacagcc atgggaacgt
    19321 ggacggtcat ttcattgtag acgaaatcat ccgcatctga gaacaagaca tggccattta
    19381 aaatcagtat tttcccaaaa gctggcgtat ccaagacttc gatatcctgc cattcacttt
    19441 ttccagcgta aagttgcttg gctgttctca gagacaattt gacatctgga gtatgaactt
    19501 cagaaaacca taaatccatc tatttctcct tatattatat ttagcgcagt tagctactgc
    19561 caaagcccaa gtggtatact tggaataagc cactgtggat tagttcattt cctccaatcg
    19621 cttgacgatt tccgaaaggc tctaaccaca gcttttgttt caattggtaa tgagtttgat
    19681 aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg gataaccaag
    19741 tagacttgaa atactatatc tggaggtact cccatgcttt atgtgggcat tgatatcgct
    19801 aaaaataaac acgatgttac agccttgaat gttccaggaa aaactgttct taaaccactc
    19861 actttttcaa ataataaagc tggttttgaa ctcttagatc tgtctcttcg acagctcaac
    19921 caagactgtc tcatcgctct tgaagatact ggacattatg cctttaatct actgaacttc
    19981 ctgcatgaac aaggatataa agtttacacc tacactcctt tgctcatcaa ggaatttgcc
    20041 aaatcattat cacttcgcaa gactaaaacg gataagaaag acgctcatgg catcgctctt
    20101 aaacttcttt ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca agtagaacta
    20161 aaaatactgg ctagacatat tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa
    20221 tacactcgtt gtcttgatat catctttcct gagttggata aaatcgttgg aaagcattca
    20281 gaatatacct accaactctt gacacgctac cctaatcctc agaaaaggct tgaggcagga
    20341 tttgataagc tgatagaaat taagcgattg accgcttcta attcaagggc tttttgccgt
    20401 gctctaaaat catcgccaaa tcatcaaatt gaaataagaa atagtttaga taaaactatt
    20461 gacttttctt atagtttgtc tttctcttaa taacgttgat atgattgacc tctggatctt
    20521 ccgtcccttg gagggagcaa ccacgttcct tggcgaattg gatatagtct acaatttctc
    20581 gtgtaatgcg ttcaccagga gccaagatag gaatccctgg aggatagcac atgacaaatt
    20641 ctccacagac ctgtccaaca gactcatcta aggtcaaact ttttctctct gaatagaaag
    20701 cttcttgtgg agacagcacc aactcgggct gaatatattc tccagctatt aagtccttcc
    20761 catctcgtga atagagtctc ttaatatcag ccagagcacc aaccaagcgc tcgatgtctt
    20821 ggatgcggtc gccgatggaa atataagcca agatattgcc gatatcacca aactcgatct
    20881 gaatgtcgta ttcgtctcgc aagaggtcat aaacctcgat acctgttaag cctattccct
    20941 gagtgtaaac tgacaacttg gttacatcaa aatcacagac cgacacacca tctattaact
    21001 cttttgagta agcatagtaa ccgccaatgg cattgatttc atgacgagcg tactcggata
    21061 gctcaacgac ttcctcaaac gactctttac cacgaagggc caagttgcga cgtgaaatat
    21121 ccaaactagc catcaataag taagaggcag atgtagactg ggtcaggttt ataatctgac
    21181 gaacgtactc gggattcatc tgctccccga ttaaaagaag cgaactttgt gtcaaactcc
    21241 caccagactt atgcatggaa actgctgcca tatcagctcc tgcatccata gcagaaattg
    21301 gaagtttacc agtgaaatgc aaatgcgctc catgggcttc atctactaaa accatcatgc
    21361 cagcttcatg agccatttct gtcaacccct ttaggtctga acagatgccg tagtaagtag
    21421 gattgttgat taggatagcc ttagcatctg gatgatcctt tatggcctgt gctactcggt
    21481 cattttcaag acctaaagcg ataccaatct taggatctac actcatctcg atatagatgg
    21541 gaatggcacc acatagaacc aacgcattga tagcagattt atggacattt cgtggcagaa
    21601 taatcttatc tcctgccttg caggttgcca gaatcatagt ctgcaccgat gaagttgttc
    21661 caccaatcat tagaaaggca tggctagctc caaaagcatc tgcagccagc tcctctgcat
    21721 cacgaataat cgaaatagga tggcctaaat tatccaaggg tttcatcgaa ttgacatcaa
    21781 tgcctacaca tttttctcct aagagttcga caagttctgg atttccccgt ccacgcttgt
    21841 gacctggaac atcaaaggga acaatccttt tcttgcgtaa cttcaccaag gcctcataaa
    21901 ttggggcttg gttttgatct aactctttca aaacatactc ctttcaatat ttttaggacc
    21961 ttatgaaaac taaggaacta aaggttgact catgaaaaaa gagcaggttt tcacctgctc
    22021 tgcaatcttc tgacgtgttt attttggttt ctgttgagta tgtctgttcc cgatgtttcc
    22081 taactctcta gtagcaaata ttacgtactt tattgatcgt ttcacaagat gacgtgtgct
    22141 ttcaccacac taaaaattta tgaattagga caagtgtcct aacatcaact tataaaagta
    22201 ggcttttaac cctatcaata atgtggcttt tcaaccacgc ttcggcattc aaccctgcct
    22261 gtccgtaggc attttttact cgggtttata tttgctagaa aacatcatct cattttctaa
    22321 gctttattac tatatcatgt ttttaagaac ttgtaaagta ttttttgata aaaaa
//
LOCUS       DAVLZG010000028        21589 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLZG010000028 DAVLZG010000000
VERSION     DAVLZG010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.028"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..1196)
                     /locus_tag="VYO72_001105"
     CDS             complement(<1..1196)
                     /locus_tag="VYO72_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1707494.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHS"
     gene            1364..2686
                     /locus_tag="VYO72_001106"
     CDS             1364..2686
                     /locus_tag="VYO72_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1707495.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2688..4574
                     /locus_tag="VYO72_001107"
     CDS             2688..4574
                     /locus_tag="VYO72_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1707496.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRNYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWKNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4742..5086
                     /locus_tag="VYO72_001108"
     CDS             4742..5086
                     /locus_tag="VYO72_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1707497.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5096..6508
                     /gene="lacG"
                     /locus_tag="VYO72_001109"
     CDS             5096..6508
                     /gene="lacG"
                     /locus_tag="VYO72_001109"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1707498.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6578..8257
                     /locus_tag="VYO72_001110"
     CDS             6578..8257
                     /locus_tag="VYO72_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1707499.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(8382..9821)
                     /locus_tag="VYO72_001111"
     CDS             complement(8382..9821)
                     /locus_tag="VYO72_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1707500.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(9825..11174)
                     /gene="trkA"
                     /locus_tag="VYO72_001112"
     CDS             complement(9825..11174)
                     /gene="trkA"
                     /locus_tag="VYO72_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1707501.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIETKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11362..12210
                     /locus_tag="VYO72_001113"
     CDS             11362..12210
                     /locus_tag="VYO72_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1707502.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12225..12773
                     /locus_tag="VYO72_001114"
     CDS             12225..12773
                     /locus_tag="VYO72_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1707503.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12780..13028
                     /locus_tag="VYO72_001115"
     CDS             12780..13028
                     /locus_tag="VYO72_001115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707504.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            13139..14821
                     /locus_tag="VYO72_001116"
     CDS             13139..14821
                     /locus_tag="VYO72_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707505.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            14806..15636
                     /locus_tag="VYO72_001117"
     CDS             14806..15636
                     /locus_tag="VYO72_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1707506.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            15829..16332
                     /locus_tag="VYO72_001118"
     CDS             15829..16332
                     /locus_tag="VYO72_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1707507.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16386..16620
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16785..17348
                     /locus_tag="VYO72_001119"
     CDS             16785..17348
                     /locus_tag="VYO72_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1707508.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17338..17988
                     /locus_tag="VYO72_001120"
     CDS             17338..17988
                     /locus_tag="VYO72_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1707509.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18016..18432
                     /locus_tag="VYO72_001121"
     CDS             18016..18432
                     /locus_tag="VYO72_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707510.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            18330..18641
                     /locus_tag="VYO72_001122"
                     /pseudo
     CDS             18330..18641
                     /locus_tag="VYO72_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            18769..19356
                     /locus_tag="VYO72_001123"
     CDS             18769..19356
                     /locus_tag="VYO72_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1707511.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            19746..21353
                     /locus_tag="VYO72_001124"
     CDS             19746..21353
                     /locus_tag="VYO72_001124"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1707512.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6410 a         3700 c         4764 g         6715 t
ORIGIN      
        1 ttgctatgtt ctatgaaaaa agcgacgata gctaatgcac aagctcctat acttccacga
       61 tgtttgttgt aaggtaaaat ttcaatttct atattacgag taaagggaac gaagtggagc
      121 tggtcttgga ttttatccct gacttcatga gtgaaaggtt gataattaag caattgactg
      181 ttgatataga ttttatcagc aggattgatg aggaggagat ttgcaataga agtggctaat
      241 aaattgactc ctttatcaat ttgttgacgt aaagcggagt cgcctaaatt ataagccgtt
      301 aaaagggtgt ctaaatgaat gtctttttca gtctttacaa ggctttttag tacagttagt
      361 tgggaatttt taaataataa ttgggcgtgt ttgattaacc aagcatccga aatatatgtt
      421 tgtaaacaac ctttttttcc gcattcacaa tattgcccat tcaattcgac aatggtgtgt
      481 ccaatttctc cgatataagg atttttagag gctcctattt tttcttttgt gaaaaaggaa
      541 gtgtaaatac ctaatccagc gtgcaggaaa ataaagttat cgggggtatt gtgtggatta
      601 aaaaggtatt gtcctatagc catacaatcg atattatttt ttacaataaa aggaaaattg
      661 aatcttttaa ttacatttaa taaattaaaa gattcccata tggggttgtt tgtaatgata
      721 cttccggagt ctttgttata atgtccaggt attgataagc caaatccaag taattttgtt
      781 tccaaaggga cgtactctat agctgttttt atcatattgg taatggtgga attgatttct
      841 gaaataggat aatcttcatt caaaatttct gtctcgaaaa gagttttccc ttgtaagtca
      901 catagactga gaaagatacc taggacgttt atttcaatac ctccaacaac atacggaata
      961 ttatctgtga tagaaatagt ttttctacgt cttccagatc cggaaaactc gctaaattca
     1021 tcaccagttt cgtatatgag ggactgttcg cttagctctt ttatgatgtt agtcgttgtt
     1081 gctggagtaa gtcctgtttc attaacaata tctgtacggg atgttgctgg atttcgatat
     1141 agaaactcca gtatagtggc tctattttgt aaaaaggctg attgttttgt aatcatttgt
     1201 ttcctccttt ggtttatttt atattaaaca taagaaaaaa tcaattaaaa ttattattct
     1261 atacaaagaa aaaaatattg taaaaataac aaaaaatata ttgacaacgc tttctgttag
     1321 tggtatattt aatttataaa aaataaaaaa aggagttccg gtgatgaaca atattttagc
     1381 gtttttagaa acaaaagtcg ctccgtttgg tgaaaaagtt ggcaaccaac ggcatttgaa
     1441 agctattcgt gaaggattta tgatggcaat gcctttgatt ttagtcggct ctttatttct
     1501 tattctaatc agttggcctc aagaggcttt tacaaattgg ctgaatagtg ttggattgct
     1561 aagtatcttg acaactatga atcagtcaac agtagcgatt atctccttgg tcgcttgttt
     1621 cggtattgcc tacaggttgt cggaaggata tggtacagat ggtccgtcgg cagggatcat
     1681 agccttatcc agttttgtat tgatggcacc tcgtttttcg agtatggttt atgataaaaa
     1741 tggggagcag gtcaagcagt tatttggcgg cgcaatacca ttttctagtc tgaatgcatc
     1801 ttctttgttt atggcgatta ctattggatt ggttacagca gagatttatc gtatgtttat
     1861 ccagcgcgga attacgataa aaatgccaag tggtgtccca gatgtggtaa gtaaatcatt
     1921 ttcagctctt ttacctggct ttactacttt tgttttgtgg gctctggtct taaaaggtct
     1981 tgaagcggca ggagttgcag gaggtctcaa cggactccta ggtgcaattg ttggaacacc
     2041 gcttaagtta attgcaggaa cgcttccagg tatgattcta tgtgttattg taaactcatt
     2101 cttttggttc tgtggagtta atgggggaca agttttaaat gcttttgtag acccagtttg
     2161 gttacaattt actacagaaa accaagaagc tgtggctgca ggacaaacac tccaacacat
     2221 tattacatta ccgtttaaag atttatttgt atttattggt ggcggtggag cgactattgg
     2281 tcttgcgatt tgtctcttcc tatttagtaa gagtcgtgcg aataaaacat taggtaagct
     2341 agctattata ccgtctattt ttaatatcaa tacagctatt ctatttacgt ttccaacagt
     2401 tttaaatccg attatgctga ttccgtttat tgctactcct acaatcaatg ccttaattac
     2461 ctatgtatca atggctgtag gattagtacc ctatacaaca ggtgtaatcc ttccgtggac
     2521 aatgccaccg atcataggag gcttccttgc gacaggagct agttggcgag gagctctatt
     2581 acaagttgtt ttgattttgg tttctgtagc aatttattat ccattcttca aaattgcaga
     2641 taaacgcaat cttgaaaaag aaaaagctac tgttggaggg aaataagatg gttatcagag
     2701 tatttgataa gcagaaaaat acttattcta gctttgcctt agaggaatta agttactata
     2761 taaatcgggt ctttaagact gacatagaac ttgtcgagga gaaggaagcg gatatttttg
     2821 taggattagt caataaagag gatagaagag accatgttct tatctcatta gacaagggta
     2881 aggggagaat tgagtctaat acaattgtag gtttacttat tggaatttac cgaatgtttc
     2941 atgaatttgg ggttgtgtat actagaccag ggcgcggaca tgactttgtt ccagagttac
     3001 gatttgaaga ttttttagat aaacagctat ctatagatga aacagccagt tactatcata
     3061 ggggagtatg tatagaggga gcggattcat ttgaaaatat actagatttc attgattggc
     3121 tacctaagat tgggatgaac agttttttca tccagtttga aaatccctac tcttttttga
     3181 aacgttggta tgaacatgaa tttaatccat atctaaataa agaacaattt tcaaatgaat
     3241 tagtacaaga attgagtgat aggttggata aagaattgca aaaaagaggt cttattcatc
     3301 atcgtgttgg tcatggatgg acaggtgaag ttttaggtta ctcttcaaaa tttggctggg
     3361 aatcaggtct tagtatttca gaggagaaga aaccctatgt cgctgaaata aacgggaaac
     3421 gagaattgtt taatacggct ccgattttaa ccagcctgga tttttcaaat ccagatgtag
     3481 ctgataagat ggtagaaatt atcaaggatt atgccaagaa aagacctgat gttaactact
     3541 tacatgtatg gttgtcggat gctcgtaata atatttgtga atgcgaaaac tgtagacaag
     3601 aattggtttc ggatcagtat attcgtattc tcaatcaatt ggatagggct ttaacgagtg
     3661 agggattaga tacaaagatt tgttttctgc tttatcatga gttgttatgg gcacctcaga
     3721 aagaaaaatt agataatcct gaacgcttta ccatgatgtt tgcaccgatt acaagaacat
     3781 ttgaaatgag ttatgcagat gtagattttg acaattccat acctacgcct aaaccttatc
     3841 tgcgtaataa aattatactt ccgaattctc ttgaggaaaa tttatcttat ctttttgagt
     3901 ggcaaaaagc atttaaagga gatagtttcg tatatgacta tcctttaggg cgtgctcatt
     3961 atggcgattt aggctatatg aaaattagtc aaactattta cagagatgta tcttatcttt
     4021 ccaacctaca tttgaacggg tacatttcgt gtcaagaatt acgtgccgga ttccctcata
     4081 attttcctaa ttatgtcatg gggcaaatgc tctggaagaa gacaagaaat tatgaagaat
     4141 tgattgaaga atacttttct gctttgtatg gggaaaattg gcagtctgtt gttgaatatt
     4201 tagaaaaatt atccatttat tcctcttgtg attattttaa tgcaattggc agccgtcaaa
     4261 gtgatgtttt agcgaatcat tattatatag cttacaatct agctgataat tttttaccaa
     4321 ttattgagga aaatatttct aagttattaa atagtcaaaa ggatgaatgg aaacagctca
     4381 gttatcatcg tgaatatgtt gtcaagatgg cgaaggcttt atatcttcaa gcaaccggaa
     4441 aaacaaggca agctcaagat gagtggaaaa atgtgttgaa ttatatccgt gggcacgaac
     4501 tgctattcca atctaatttg gatgtttatc gtgtaattga agtagcaaaa aattacgctg
     4561 gtttccactt ataaatcata agtctagaaa atgaaccaag gtattcagag aagattgatc
     4621 ctaaatatta tgaaatttaa ggatttttaa gatatttagg gtcgactttc tatttgtatc
     4681 gtagcgaagt cattttaata atgatgtgta aaagatggtt caagattgag gaggaagaaa
     4741 gatgaaatca aaagaagaaa taaatatgct tggttttaca attgtcgctt acgcaggaga
     4801 tgcaaggtca gatttgatgg atgctttggc gtttgcgaga gatggatatt ttgaacaggc
     4861 aagagaattg gttgagtctg caaacgactc aatagtgtct gcccatcgag aacagactaa
     4921 tttattagcg gaggaggcat atggagataa ttttgaagtg agttttatca tgattcatgg
     4981 tcaagatact ttgatgacaa cgatgctatt gtatgatcag gtaaagtttt ttattgatga
     5041 atatgaacga attcgaaaga ttgaagaaca tattggtttg caatgaggat tagtcatgga
     5101 aaatttacag gttaaagcct taccgaagga gtttttatta ggagctgcta ccgctgctta
     5161 tcaagtagag ggtgcaacta gggtagatgg caaaggaata aatatgtggg atgtttattt
     5221 gcaagaaaat agtccgttct taccagatcc agctagtgat ttttattatc gttacgaaga
     5281 ggatatagct ttggcggcag aacatggttt gcaggctttg cgtttatcta tttcttgggt
     5341 tcgtatattt cctgatatag atggggagcc gaatatattg gctgttcgtt attaccatag
     5401 agtctttcag tcctgcttaa aatataatgt gattccgttt gtttctttac atcattttga
     5461 ttcgcctcag aaaatgttag aaacagggga ttggttgaat agagagaata ttgatcgttt
     5521 catacgatat gctcgctttt gtttccaaga atttacagaa gtcaagcatt ggtttacaat
     5581 caatgaactg atgtctcttg ctgcaggcca atacatagga ggtcagtttc ctccgaatca
     5641 ccattttcaa ttatctgaag caattcaagc aaatcataac atgttgttgg cgcatgctct
     5701 tgcagtcctc gaatttcatc aattagggat tgagggaaag gtaggttgta ttcatgcttt
     5761 aaagccaggc tatcctattg atgggcaaaa agaaaatatt ttggcagcta aacggtatga
     5821 tgtttataat aataaatttc tattagatgg aacttttttg ggctactaca gtgatgacac
     5881 gctttttcac ttgaatcaaa tattggaagc taataattct agctttatta ttgaagatgg
     5941 tgatttagaa attatgaaaa gagctgcacc tcttaatacg atgtttggga tgaattatta
     6001 tcgttcagaa tttattcgtg aatacaaagg tgaaaataga caagaattta attcaacagg
     6061 aataaaagga cagtcttctt ttaaattaaa tgctctaggt gaatttgtaa aaaagcctgg
     6121 tattccgaca acagattggg attggaatat ttatcctcaa gggttatttg atatgttgct
     6181 tcgtatcaaa gaagaatatc ctcaacatcc ggtcatttat ttaactgaaa atggtacagc
     6241 ccttaaagag gttaagccag agggcgagaa tgatattatt gatgacagta aaagaatccg
     6301 ttatattgag caacatttac acaaagtttt agaggctcga gataggggag tcaatattca
     6361 aggctatttt atatggtctt tgcaagatca attttcttgg gcgaatggct acaataagcg
     6421 atatggtctt ttctttgttg attatgaaac acagaagaga tatattaaga aaagtgctct
     6481 ttgggtaaaa gggctaaaac ggaattaagg ttagcgattt gactgatgtt taatatattt
     6541 taactatgag cttaaatttt ttacaggagg agtttttatg gataagttag tcgctgccat
     6601 tgaaaagcaa caagggaaat ttgaaaaaat ttctactaat aattatatga tggctattaa
     6661 agatggattc attgctacta tgcctttaat tatgttttca agctttttga tgattattat
     6721 tatgattcct aaaaatttcg gagtagagtt accgagtcca gctattgcct ggatgaggaa
     6781 agtgtatatg ctaaccatgg gagttttggg tgttattgtt tcagggacag ttgcaaagtc
     6841 attggctgga aatgttaata gaaaaatgcc tcctggaaag gtaataaatg atacttctgc
     6901 aatgttggcg gccatatgtg gctatcttgt attaactgta acgcttgtag ttgatgagaa
     6961 aacgggatct acaagtttgt cgacaaacta tttaggatct caaggattga taacttcgtt
     7021 tgtcagtgcc tttattactg taaatgttta ccgattctgt attaagcgag acattactat
     7081 tcatttacct aaggaagttc ctggggctat atcacaagct tttagagata tttttccttt
     7141 ttcttttgtt ttacttatta gtggtttgtt agatattgta tctcggttta gtttagatgt
     7201 tccttttgcc caagtatttc aacaactatt gactcctatt tttaaggggg cagaatcata
     7261 tcctgctatg atgttgattt ggtttatgtg cgctttgctt tggtttgttg gaattcatgg
     7321 accatctatt gtcttacctg ctgttacagc tttacaactg agcaatatgg aagagaatgc
     7381 tcaacttctt gcaaatgggc agtttcctta tcattcttta acgcctaatt tcggaaatta
     7441 tatcgctgct atcggaggaa cgggggctac ctttgttgta ccatttattt tgattttctt
     7501 tatgcggtct aaacaattaa aatcggtagg taaagctaca attactcctg ttttatttgc
     7561 agtgaatgaa cctcttctat ttggtatgcc agttattttg aatccctatc tttttgtacc
     7621 ttttttgatg actccaccag tgaatgtatt tctaggaaag gtctttattg atttctttgg
     7681 aatgaatgga ttttatatcc agttaccttg ggcctttcct ggtcccttgg gattgttaat
     7741 tggaacgaat tttcaatcta tctcctttgt atttttatct ttgattttag ttgtcgacat
     7801 attgatttat ttgccattct gtagagcgta tgatagacag ttactgatga aagaagatgt
     7861 tgcaagctca aatgatatta ttttagagga ggagacaagt gaaataatgc ctggtgagtt
     7921 agatgaaata aaaagtaagg agttgaaagt actggttctt tgtgcagggt ctggaacaag
     7981 tgcgcaatta gccaatgcaa ttaacgaggg cgctcaatta gcagaagtta gagtgattgc
     8041 gaattcagga gcgtacggag ctcattatga tattatgggt gtttatgatt taattattct
     8101 ggctccacaa gttcggagtt attatagaga gatgaaggtg gatgcagaaa gattaggtat
     8161 tcagatagtt gctaccagag gaatggaata tattcattta acaaagaatc caagtaaagc
     8221 cttacaattt gtattggagc attaccaagc tgtgtagtaa gtttttccat cttttatttg
     8281 agtaagaact ttgcttacag acaggcttgg atttaaaaac gttccccctt tttaatataa
     8341 aaatccctct ttcacaattg taaaaagagg gattttgtat tttatctctt agaccaagtt
     8401 cttttcataa agagaaggag gattgggtaa atctccaagc gccctgcaat cattgcaaag
     8461 gagaggagaa tttttgagat gggactaaag attgagaaac tagaagtggt tcctagaata
     8521 ggcccgatat tattgaaaca gctaaagaca gcgctggtca cgaccagaaa atcattgcta
     8581 tctaggctga caataaagat aagcgctagc aaaatcatag catagatgac aaagtacttg
     8641 agaatcttat gctgggtatc tttatcaatc accgtttgat tcacatggag agtcaaaaca
     8701 cggtggggcg ataggattga caaaatttgg tttttggcaa tttttgaaag gatgaggcct
     8761 cgaataatct tgagtccacc tgcagttgat ccagcagagc caccgattgc catgaggaaa
     8821 aggaggataa actgggagaa gaggggccag ttggtaatat ctccatatcc aaaaccagtt
     8881 gttgtaatga tgttggaaac ctggaagaag gtcatttcaa agctctttga aaaccctggg
     8941 tagaggtaga gggtgttgag gctaatcaag cctgtagaaa ccagtacaat gaccaagtaa
     9001 gcccgaagtt cttcgtcacc aaagaaggcc ttgatgcgac ggagcatgag gtagtagtag
     9061 aggttgaaat ttaccccaaa aaccagaact ccgatactga ccagataggt aatcagtgag
     9121 ctgccatagt gggcaattcc gtcgttatag acggtaaagc ctccagttcc cgctgtcccc
     9181 atagcaatga caaaactatc gtagagaggc ataccagcta gataatagat gatgacaaag
     9241 agggagaaga gagctagata aaggagatag agaatctggg cagtgttttt tagtttggat
     9301 acaaccttgc caaaaacagg acctggaacc tcagccttca tcacctctag gtggctattt
     9361 ttggcattgt ccataatagc aagtgcaaaa acaagcactc ccatccctcc aatcaagtgg
     9421 gtaaaacttc gccagaagag gagggaacgg ctgagaaccg aaacgtcgtt caaaatactt
     9481 gctccagtag ttgtaaaccc agaactaatt tcaaaaaagg catcaataac gctagggatt
     9541 tgcccagaaa agacaaaggg gagaccacca aagaaagacc aaaggatcca acagagggca
     9601 acgatcaaga ctccctcctt ggcataaatc cgttgatttt ttggcttctg taaactccct
     9661 gaaccgccta acaatacgag aatccctatg gtcgaaaaga gggctgtaaa gacttggctc
     9721 gattcacggt aatagacagc gatagccaca ggaaccaaga ggagaacagc ttcaatcaaa
     9781 agtaactttg aaaggaggta acgaatcata cttttattca tttcttacct cgcaatcaag
     9841 tcataaatct tggtgatgtt tggcaacaag gttgttacta ggagcttgtc tccaacttcc
     9901 aacatatcct ccccagttgg gaaaatagtc ttgccctttc gaataatggc tgcaataaga
     9961 accccttttt tcaatttcag ttgagaaaga ggtttggcag tcattttatt ggcttccttg
    10021 atatggaatt gcagggtttc gatttggcca ttggctagat ggtgcatggc ttgaaggtct
    10081 gaatactggg cattaactcg accacgaata aagtgcataa tcgtatctac agcgatgctt
    10141 ttaggtgtga tgatacttga aaaatcaggc gcattgataa tctcgaggag actggtacga
    10201 ttgaccttag taatattttt ctgtacacct accctgtcaa ggaacataga tgtaatcaga
    10261 ttttcctcat cgactcctgt tagagtcgca acggcatcat agtgttgagc actttcttcc
    10321 agcaggatat cttttgcggt tccatctcct tgaacgatgt agagatttgg gaatttctcg
    10381 ctaaagaagc tagcgatttc aggattgatt tcaataacct tggtttcgat acgactatct
    10441 ttgaggatac ctaatagata ataggcaatt ctaccagctc caacgatgag aaggctcttc
    10501 acggcgcgtg atttaaaata attatggaag agtatcatat cgacacggtt accagtgaca
    10561 aagattctat ctttatcctg tacagtcatg tcaccgcttg gaatgataat ttgatgatcc
    10621 ctctctatcg cacagacaat gacattacca aattttttac gaaaatcaga aatgggcatt
    10681 tggcaaagac cgctggtgga cttgacgaca aattccatga ggctaacgcg tccaccagca
    10741 aagcgttcga cagacagggc gttggggaag tcaatgatat tcgcgatagc gcgggcagcc
    10801 aagagctcag gattaacgat aagagaaaaa ccgagaatat tcttttcctt gaaataagag
    10861 ttagaatatt cagggttccg cacccgaacg atagtttctt tagctcccat tttcttggct
    10921 agaactgctg caatcatgtt gacttcatcg tgctcagtca gggcgataaa gatatcacaa
    10981 tcttggacgc tggcttgctc aagaatggca aaatcggccc cgttaccaag gataccaatg
    11041 atatcaaagc gactgacaat atgattgaga acagcttcgt cttgctcaat cagcaaaaca
    11101 tcatgctttt ctgcaaccaa ggagcgacag agggcaaaac caacttttcc ccctccgaca
    11161 aggataattt tcataataaa acctactttt tcatgatgta actatcatac cctttttcaa
    11221 gaaaaaatgc acctactagc taataacaag agcttttagt gaaaattcgc tataaggtaa
    11281 aactataccc taaccaattg aaatagctat tagcgacttt ctctgaaata tggtatgata
    11341 aaggatatac aaggagataa aatgaataat aatttactgg tattacaatc agactttggt
    11401 ctggttgatg gtgcggtatc ggctatgatt ggagtggctt tagaagagtc tccaacctta
    11461 aaaatccatc acttgacgca cgatatcacg ccttataata tttttgaggg gagctatcgt
    11521 ctctttcaga cggtggatta ctggcctgag ggaacgacgt ttgtatcggt tgtcgatcca
    11581 ggtgtcggtt cgaaacgtaa gagtgtagtt gccaagactg caaaaaatca atacattgtc
    11641 acgccagata atgggacgct ttcctttatc aagaaacacg ttggcattgt agccattcgt
    11701 gagatttctg aggtggccaa taggcgtcaa aacacagagc attcttatac cttccacggt
    11761 cgtgatgtct atgcctatac tggtgctaaa ctggccagtg gtcacattac ttttgaggaa
    11821 gtagggccag agctcagtgt ggaacagatt gtagagcttc cagtcgtagc gaccatcata
    11881 gaagatcatc tggtgaaggg agccattgat attctggatg tgcgtttcgg ttcgctttgg
    11941 acctctatca cacgggaaga attttacaag ctggaaccag aatttggtga tcgttttgaa
    12001 gtgaccatct atcatgctga tatgctggtc tatcaaaatc aggttgtcta tggcaaatca
    12061 tttgcagatg tgagaattgg gcaacccatc ctttacatca actctctcta tcgtttaggt
    12121 ttggctatca accaaggttc ctttgccaag gcctataatg taggtgtcgg ttcatcttgg
    12181 accattgaaa taaagaaaat agaaggataa aataggagaa tagtatggaa attaaattta
    12241 caattaaaca agttgttgct gtcggaattg gcgctgccct ctttgtcgtc atcgggatga
    12301 tcaacattcc aacccctgtt ccaaatacaa gcatccagct tcagtatgcg gtacaagcgc
    12361 tactttctat tatttttgga ccgattatcg gtttgcttgt cgggttgatt ggtcatgcaa
    12421 tcaaggactc tcttgctggt tatggtctat ggtggacttg gattatcgct agcggactct
    12481 ttggtttagt tgtgggactt tttagaaagt acgttcgcgt gatcaatggt gtttttgact
    12541 ggaaagatat tcttattttt aacctcattc aactacttgc aaatgccctt gtttggggtg
    12601 tcttggcacc acttggagat gttgtgattt atcaagaagc ggcagaaaaa gtatttgcac
    12661 aagggattgt tgcgggaatt gccaatggtg tatctgtagc tattgcagga actcttctct
    12721 tacttgccta tgcaggaacc caaactcgtg caggaagttt gaaaaaggac taatactcaa
    12781 tgaaaatcaa agagcaaact aggaagttag ccgcaggttg ctcaaaacag tgttttgaaa
    12841 ttgtggatag aactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
    12901 acgaagtcag taaccatacc tacggcaagg cgaagctgac gtggtttgaa gagattttcg
    12961 aagagtataa aatgatgggg aaggctgggc aactagtctt tttcgatgtt tatagattag
    13021 ttaggtaagt aagctaggat aggaatcttt ttggcgctaa gattttaata ggagagactg
    13081 caagaagggc ttgatttatg ataaaataga agtctaagaa gcgaatgaag agagtaagat
    13141 gaaagaagct ataattgagt ggaaggattt ctctttccgg tatgaaacac aacaagaacc
    13201 gaccttgcaa gggatagact tgaccattta caagggagag aaagtcttaa ttgttggacc
    13261 atctggatca ggtaaatcta ccttgggtca gtgtttgaat gggattattc ccaatattta
    13321 caagggtcag acatatggag aatttttgat aaagggtcaa acagcctttg atatgagcat
    13381 ctatgataag tctcatctgg ttagcacagt tttgcaggat acagatgggc agtttattgg
    13441 cttgtctgtg gcagaagatt tggcgtttgc tctggaaaat gatgtgacag ccctagatga
    13501 gatgaaaggt cgtgtttata aatgggctga aaagctggac cttcttcctt tactggatca
    13561 gcgccctcag gatttgtcag gtggacaaaa gcagcgagtc agtctggctg gtgtcttgat
    13621 tgatgaaagt ccgattctct tgtttgatga gccactcgcc aatcttgatc ccaagtcagg
    13681 tcaggatatt atcgaattga ttgaccagat tcataaggag gaggggacga cgacccttat
    13741 tatcgagcac cgtttggagg atgttctgca ttgccctgtg gatcggattg tcttgataaa
    13801 cgatggtcgt atccttttta atgggagccc tgaccagtta ctggcgactg atttgttgac
    13861 ccaaaatgga attcgcgaac ccctttatct caccactctc cgtcaattgg gtgtggattt
    13921 agtcaaggaa gaacaattag cgaatctgga taacttgtct atctcaaaag gtcaggttca
    13981 gttgcagaat gaactggcaa aagaaacccc agcattgcag tcactcttta gactagagga
    14041 agtatctttt tcttatgatg atagaccgat tttaaaatcc ctacatttag atattaaaaa
    14101 gggtgaaaag attgctattg tcggaaaaaa tggagcaggg aaatcaactc tagccaaggc
    14161 tataagtagc tttattcaga cggaaggacg ctatctttgg gaaaaacagg atataaaagg
    14221 cgattctgtt gcagagcggg cggaacgagt aggatatgtg ctacaaaatc ctaatcaaat
    14281 gatttcaacc aatatgattt ttgatgaggt ggctctaggg ctccgtttgc gaggtgtgga
    14341 tgagaaggaa attgaaacga gagtatatga aaccttgaaa atctgtggac tttatgaatt
    14401 ccgtaattgg cctatttctg ccctgtcatt tggtcagaaa aaacgtgtca ccattgcttc
    14461 aattttggtc ttaggagctg aaattattct cctagatgaa ccgactgcag gtcaagatca
    14521 gaagaactat actgagatta tggaatttct cgaagagtta catcaaaaag ggcataccat
    14581 tgtcatgatt acccatgata tgcaattgat gctggattat tcagaccggg tccttgtcat
    14641 ggtggatgga gaattgattg ccgatactgt tccagccagt ctgttgagcg atcctgagct
    14701 gttagtaaaa gccaatctaa aagaaacctc catctttaac ttggctaaga aactagatgt
    14761 ggatccactg gatttaacgg cattttacaa agaaaggaga gagggatgca agctaaatta
    14821 atcggttacc agcatagaga tactgtgatt catcgcttgt caggagctgg gaaacttctc
    14881 tttttcattc tggtatcatt ggcggccatg attagctatg ataccagaat gctcttgctg
    14941 attgccatct tttcagtctt tctcctctat ttatcagaaa ttcgctttaa agatgtttcc
    15001 tttgtagccg tttttgcgac ggtatttgcc gttttaaacg ttttgatggt ctatctcttt
    15061 tctcccgagt atggggttgg actttatgga gagagaagtg tgatttggca gggaatcggt
    15121 gtctacactc taaccagcca ggagctcttt tatctgctaa atttggccat taagtatctt
    15181 tgcaccattc ctctggctat tatctttttg atgacaaccc atcctagtca gtttgcttcc
    15241 agtttaaatc aaattggtgt gccctataag attgcttatt ctgtcagcct gaccttgcgc
    15301 tatattccag atttgcagga agaattcttt actatcaaga tgtctcagga ggcgcgtggg
    15361 atggaattat ccaagaaagc ttctcttatg caacgaatca aaggcaatct gctcattatt
    15421 acgcccttga tttttagctc gctagaacgc attgatacca ttgcgactgc catggagctt
    15481 cgccgctttg ggaaagagaa aaaacgcaca tggtatagtt atcaggcctt gaaaaaagga
    15541 gactatatta ccttgctctt ggcaaccttg tttttagtag ttagtttact acttatcttg
    15601 cagaatcagg gacgatttta caacccttgg aaatagcttg aaaaaattga aaaaatcaag
    15661 tcatttctat tgacaatgat tctgaaagtg ttatactaag aaagtagttt cgctgattta
    15721 cttcaaacct gttgtgaggt aagttaacga tgccttaacc acgctgtttg ctgagcttga
    15781 ctccgggcag tgtggctatt tttttgcaat ggtgaaagga agcaagtcat gacaaatcac
    15841 attgtattat ttgaacctca aattccacaa aatacgggca atatcgcgcg tacttgcgct
    15901 gcgaccaatt ctcccctcca catcatcaag cctatgggct ttcctattga tgaccgcaag
    15961 atgaagcggg ctggattgga ttactgggat aagctagaga tttattttta cgagagtttg
    16021 gaagatttca tatctcagat gaagggaaaa ctctatctga tttcgaaatt cgcggaaaaa
    16081 gtctattctg aggtggattt atcgactgac gaggaccatt attttctctt tggacgtgaa
    16141 gacaagggct tacctgaaga ttttatgcga gaacatcctg agaaggctct ccgtattccc
    16201 atgaatgatg aacatgtccg cagtctcaat gtgtctaata ccgtctgcat gattgtctat
    16261 gaggctcttc gccagcagaa ctttgcaggt cttgagctcg tccataccta tgaagtggat
    16321 aaattgaaat aaaaaatgaa aatgaacaaa atgcttgcgc ttgcaagcgt tttttgttat
    16381 gataaaagag tcttcagggc agggtgtgat tcccgaccgg cggtgacttt aactaggaaa
    16441 tgatcttttc cttttatact ttgttgacaa gctttgccta accagaagtt atgcctacag
    16501 cttgtcgcct agtctaaaag aaaaatctct atttccttct ctttaaagaa gtccgcgagc
    16561 gcaagctgat gtggtgagat tccacaaccg acagtatagt ctggatggga gaagacgaaa
    16621 gaatagcttt gtctgttttg atagatttat agccggattg taaccacttg ctttgttttt
    16681 ctttaataga gtaagaggga acttttggga tataaaaagt gagaatagat agaggaatcc
    16741 tttccaactt cttctgattt tatagaaaat tggaggaacc tgttatgaca aacacacgtc
    16801 gactttcgac cattgcaatt ctatcagcca tctcatttgt gctgatgtac tttgactttc
    16861 cgcttttacc agcggcatct ttcctcaaga tcgaatttag tatcttgcca gtccttgtgg
    16921 gtctggtggt catggatttg cctgctgctc taggagtgct cttgcttcgc tcactattga
    16981 aattgcttct taacagccaa ggagtgaata cttacattgg tttgccgatg aatatcgtag
    17041 ctttgggagt ttttgtcatc gtatttgctt tgatttggaa aaaggaacgg acaacccttc
    17101 gtttcctact aggctctcta gctggaactg ttggtttaac cttggccatg ttggttctca
    17161 actatgttta tgctgttcct ttgtacgcta agtttgctaa ctttgatatt ggaaaaattt
    17221 tgggactttc caactaccta atgaccatgg tattaccttt taacttgatt gagggtgtaa
    17281 tcttttccgt ttcattctgg ttgttgtacg tccttttgaa accaacctta aaacactatg
    17341 aaagataaac aaacattttt aatgaagggc agttttgccc ttttactttt cgttattctt
    17401 ggctatatgg tcaaatttta ccctgaaacg ctggtcggtt ttgaccaatc gattcagact
    17461 gccattcgag gagacttacc agattatttg actattcttt ttcgatccct cacacatctg
    17521 attgatattc cagtgattat cacttgggtt gtcattatag cttttgtctt ttatcgtaag
    17581 cgatggaaga tagaaagttt cttcatgctg ggaaatctgg ctttggcagg tcttttaatc
    17641 gtgaccttta aaaatatcta ccagcgccca cgaccagcta tcttacatct ggtggaggag
    17701 aagggatttt ccttcccaag tgggcattct ctagctgtaa cgctgatggt agggactttg
    17761 attgttattc ttagtcagcg gattaaagat caggtctgga gaaaaatcgt acaaatcgtc
    17821 cttggcctct acctagtcag tgtgctggta tcaagagtct atctgggagt tcactaccca
    17881 tcagatgttc ttgccagttt ctgtgtgggt ttgggagtct tgtttatcga gtttcccttc
    17941 tatgacaagc tccgcttcca atggcgattt aaaggcaaac agaagtgagt atcgaattcc
    18001 ctttaggaga aagaaatgaa agtcaatata gtagatcttc atccgactca actatattta
    18061 tcagaaaaga agttgcaaga tattcagatg ctttaccagt cggcagaaac aaaccaagtc
    18121 gatccaatca gtattcttgc ctttggagat tgtttgctga ttacagatgg gcatcacagg
    18181 gcttatcagg ctttattggc aggtcgggat acgatttctg ctgagtggga tagagatggt
    18241 ggtgatgaac tatatcatct ctatgcgcaa gcttgcgagg aaagaaagat ttactctgtt
    18301 tttgatttaa aaaatcatat cttacctctt tggatcggca tggtgagctt ttttggattg
    18361 aagtcaagga gaagggagaa tggtttccaa ttggggatat tacactatct caggataatc
    18421 tccccattgt gattgggaat tccgcttacc aacatcgagg acttggaaaa aagattctaa
    18481 gtgctttgat tgaattggct cgagtaaaag gatggaaaga attgagagtc aaggaaatct
    18541 acacctacaa tcatgcttct aggaggtgtt tcaagtcgct tggatttgtg gaaaatggag
    18601 caacagaaaa aggaaggagt tttatattgg aattagtcta atcctgccac tttctccccc
    18661 ttaacctttg actattccgc aaaattatcg taaaataaag agtaaatgat aaaatgaggt
    18721 cagagtctgt tcgctctggc gatagtagta taaatgagga gaaacgcttt ggaattagaa
    18781 gtatttgctg ggcaagaaaa aagtgaacta tctatgattg aggtagcgcg tgctatatta
    18841 gaacttcgtg gtcgcgatca tgagatgcat tttagcgatc ttgtaaacga aattcaaaac
    18901 taccttggaa catcaaacag cgatatccgc gaagctttgc ctctgttcta cacagagttg
    18961 aactttgacg gtagcttcat ctcacttggg gacaacaaat ggggtcttcg ttcatggtat
    19021 ggtgtggacg aaatcgacga agaaatcatc gctcttgaag aaaatgacga cgatgaagta
    19081 gcaccaaaag ctaagaaaaa acgtgtcaat gcctttatgg atggtgattc agatgccatt
    19141 gactacaatg cagatgatcc agaagacgaa gatgcatacg aagcagatcc agctctttca
    19201 tacgatgatg aaaatccaga tgatgaaaaa aatgaagtgg aagcttatga tgcagaaatc
    19261 aacgaaatcg ctccagatga cttgggagaa gatgtggatc tcaacgaaga cgacgacgag
    19321 ttttcagatg acgacgctga aaccagcgag gaataagagt tagctattga caattatcct
    19381 atttttaggt atcatattgt ttgggcacct cttttagagg tcggggctcc ctagttctta
    19441 gggagctatt tttgtttttt caagaagtta tcttcttgta ttttatactc aatgaaaatc
    19501 aaagagcaag ctaggaaact agccgtaggc tgctcaaaac actgttttga ggttgtagat
    19561 aagactgaca aagtcaggaa cacatatcta cggcaaggcg acgttgacgc ggtttgaaga
    19621 gattttcgaa gagtattagt tgtgaatctg gtgcagtcgt cccagattat tcttattagt
    19681 agggtcttgt tttctatatc ccctcgtagt taacaagacc ttgagcattt tagaaagagg
    19741 aatctatgtc tacgaaatat atttttgtaa ctggtggtgt ggtatcgtct attgggaaag
    19801 ggattgtggc agcgagtcta ggccgtctct tgaaaaatcg tggtctcaaa gtaaccattc
    19861 aaaagtttga cccttatatc aatattgatc cgggaaccat gagtccttac cagcacgggg
    19921 aagtttttgt gacagatgac ggagctgaga cagatttgga cttgggtcac tatgaacgtt
    19981 tcatcgatat caatctcaac aaatattcca acgtgacaac tgggaaaatt tacagtgaag
    20041 ttcttcgtaa agaacgccgt ggagaatacc ttggggcaac tgttcaagtc attcctcata
    20101 tcacagatgc tttgaaagaa aaaatcaagc gtgccgctct aacgaccgac tctgatgtca
    20161 ttatcacaga ggttggtgga acagtaggag atatcgagtc cttgccattc ctagaggctc
    20221 ttcgtcagat gaaggcagat gtgggtgcgg ataatgtcat gtatatccat acaaccttgc
    20281 ttccttacct caaggctgct ggtgaaatga aaaccaaacc aacccaacac tctgtcaaag
    20341 aattgcgtgg cttgggaatc caaccaaata tgttggttat tcgtacagaa gagccagctg
    20401 gtcaaggaat taaaaataaa ctggcccagt tctgtgatgt ggcaccagaa gccgttatcg
    20461 aatcgttgga tgttgaacac ctttaccaaa ttccactgaa cttgcaggca caagggatgg
    20521 accaaattgt ttgtgatcat ttgaaattag acgcaccagc agcggctatg acagaatggt
    20581 cagccatggt ggacaaggtc atgaacctca agaaacaagt taagatttcc cttgttggta
    20641 agtatgtgga gttgcaagat gcctatatct cagtggtcga agccttgaaa cactctggct
    20701 atgtcaatga tgcagaagtt aaaatcaatt gggtcaatgc caatgatgtg acagcagaga
    20761 atgtagcaga actcttgtct gatgcggacg ggatcatcgt accaggtggt tttggtcaac
    20821 gtggtacaga agggaaaatc caagccatcc gctatgcgcg tgaaaatgat gttccaatgt
    20881 tgggagtctg cttgggaatg cagttgacat gtatcgagtt tgctcgtcac gttttaggtc
    20941 ttgaaggtgc caattctgca gagcttgcac cagaaacaaa ataccctatc attgatatca
    21001 tgcgtgatca gattgatatt gaggatatgg gtggaaccct tcgtttggga ctttatccgt
    21061 ctaagttgaa acgtggctct aaggctgctg ctgcttatca caatcaagaa gtggtgcaac
    21121 gccgtcaccg tcaccgttat gagtttaata atgccttccg tgagcagttt gaggcagcag
    21181 gttttgtctt ttcaggagtt tctccagaca atcgtttggt agaaatcgtg gaaattcctg
    21241 aaaataaatt ctttgtagct tgtcagtatc accctgaact gtcaagccgt ccaaaccgac
    21301 cagaagaact ctacactgcc tttgttactg cagcggttga gaacagcaat tagcaaaatc
    21361 agaacctttg agaaaaatct cagaggtttt ttgcatacga tgatattgca gtatatctga
    21421 ggtaggagtc ctctgtatgt acctgctacc gttgaaatca atagcgactc cctcttgccc
    21481 tgtgctagtg aatggattta tcagtatatt gaaatgaaat aaaatctgaa caaattaatt
    21541 cggaaagcca aattaatttc tagcaaagtt ttaggaactg gattgtatc
//
LOCUS       DAVLZG010000029        21313 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLZG010000029 DAVLZG010000000
VERSION     DAVLZG010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.029"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            55..351
                     /locus_tag="VYO72_001125"
     CDS             55..351
                     /locus_tag="VYO72_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1707513.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDLVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            472..1416
                     /gene="manA"
                     /locus_tag="VYO72_001126"
     CDS             472..1416
                     /gene="manA"
                     /locus_tag="VYO72_001126"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1707514.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1437..2800)
                     /locus_tag="VYO72_001127"
                     /pseudo
     CDS             complement(1437..2800)
                     /locus_tag="VYO72_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3028..3777
                     /locus_tag="VYO72_001128"
     CDS             3028..3777
                     /locus_tag="VYO72_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1707515.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3797..4252)
                     /locus_tag="VYO72_001129"
     CDS             complement(3797..4252)
                     /locus_tag="VYO72_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1707516.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4272..5447)
                     /locus_tag="VYO72_001130"
     CDS             complement(4272..5447)
                     /locus_tag="VYO72_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1707517.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5506..6351)
                     /locus_tag="VYO72_001131"
     CDS             complement(5506..6351)
                     /locus_tag="VYO72_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1707518.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6476..7033
                     /locus_tag="VYO72_001132"
     CDS             6476..7033
                     /locus_tag="VYO72_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1707519.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7052..7519
                     /locus_tag="VYO72_001133"
     CDS             7052..7519
                     /locus_tag="VYO72_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1707520.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7608..8237
                     /gene="upp"
                     /locus_tag="VYO72_001134"
     CDS             7608..8237
                     /gene="upp"
                     /locus_tag="VYO72_001134"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1707521.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8411..9001
                     /gene="clpP"
                     /locus_tag="VYO72_001135"
     CDS             8411..9001
                     /gene="clpP"
                     /locus_tag="VYO72_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1707522.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9080..9328
                     /locus_tag="VYO72_001136"
     CDS             9080..9328
                     /locus_tag="VYO72_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1707523.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9430..10590
                     /locus_tag="VYO72_001137"
     CDS             9430..10590
                     /locus_tag="VYO72_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1707524.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDSLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10858..11727
                     /locus_tag="VYO72_001138"
     CDS             10858..11727
                     /locus_tag="VYO72_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1707525.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11731..12687
                     /locus_tag="VYO72_001139"
     CDS             11731..12687
                     /locus_tag="VYO72_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1707526.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12687..13451
                     /locus_tag="VYO72_001140"
     CDS             12687..13451
                     /locus_tag="VYO72_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707527.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13451..14161
                     /locus_tag="VYO72_001141"
     CDS             13451..14161
                     /locus_tag="VYO72_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707528.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14469..15125
                     /locus_tag="VYO72_001142"
     CDS             14469..15125
                     /locus_tag="VYO72_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1707529.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15233..16328
                     /gene="prfB"
                     /locus_tag="VYO72_001143"
     CDS             join(15233..15304,15306..16328)
                     /gene="prfB"
                     /locus_tag="VYO72_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1707530.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16346..17038
                     /gene="ftsE"
                     /locus_tag="VYO72_001144"
     CDS             16346..17038
                     /gene="ftsE"
                     /locus_tag="VYO72_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1707531.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17031..17957
                     /locus_tag="VYO72_001145"
     CDS             17031..17957
                     /locus_tag="VYO72_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707532.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18243..20423
                     /locus_tag="VYO72_001146"
     CDS             18243..20423
                     /locus_tag="VYO72_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1707533.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20475..21290
                     /locus_tag="VYO72_001147"
     CDS             20475..21290
                     /locus_tag="VYO72_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1707534.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
BASE COUNT         6527 a         4015 c         4645 g         6126 t
ORIGIN      
        1 tataatgctt tttgatttta gtttagtatt atcgtagaaa atggactcgg tgctatggat
       61 acaccggatg agaatggtta tgtagcagat aactatcgga ttacttactt agaggcccac
      121 atcaaggcca tgcgagatgc catttaccaa gacggggttg acttgcttgg ttatacgact
      181 tggggctgta tcgatctggt ttcagctggc acaggggaaa tgaataagcg ctatggcttt
      241 atctatgtag atcgagataa tgtaggaaac ggagctctca aacgtagcaa gaagaagtcc
      301 ttctattggt acaaggatgt cattgatagc aatggtgcaa gcatcgggta gagcacattt
      361 gtttactatt tttataaaat cttctccctg ctttataaga tgtaaaaaag agttcaattc
      421 gaactctttt tttgctataa tgaggggaga aaaatcagac aggagatcga catgtcagaa
      481 ccattatttt tacaatcagt tatgcaagaa aaaatctggg gtggagccaa gctacgtgat
      541 gagtttggct acgacatccc aagtgaaaaa atcggagaat attgggccat ctcagcccat
      601 ccaaatggag tctctaaagt tgccaatggt cgttacgagg gaacagatct tgctactttg
      661 tatgcggaac accgtgaatt atttggcaat cgtccagaac ctgtatttcc acttttgacc
      721 aagatcctcg atgccaacga ctggctcagt gtccaagttc acccagacga tgcttatgga
      781 ctcgagcatg aaggcgaact cggaaaaaca gaatgctggt acattatcgc agcggatgaa
      841 ggttcagaga ttatctacgg tcacaatgcc aagtcaaaag aagaactccg ccagcaaatc
      901 gaggataaga actgggatgc gctgttgaca aaagtgccag ttaaagcagg agatttcttc
      961 tatgtaccaa gcggtaccat gcacgctatc ggggcgggta tcttgattct tgaaacccag
     1021 cagtctagcg ataccactta ccgtgtctat gactttgacc gaaaggacga taagggcaac
     1081 ttgcgtgaac ttcaccttga aaaatctatc gatgtcttga acattggtga acccgcaaat
     1141 agccgtccag tgacaatcaa agcagatgat ctacgttcca ctctccttgt atccaatgat
     1201 ttcttcgcag tttacaaatg ggaaattact ggaaaagtta actttgaaaa gacagctgac
     1261 tacagcttgt tgagtgtctt ggctggtcaa ggtcaactaa ctgttgacgg gaaaaactat
     1321 ccaatccaaa aagggagaca ctttatccta ccaagtgatg ttgaatcttg gactttagaa
     1381 gggcaagatt tggaattgat tgttagtcat ccataaaaag aaagggcctg agttcactac
     1441 tcaagtcctt tttgattaca taaattgggc gatgaagacc acgatgatga ttggaatgac
     1501 gaaacgaaga aacgaaggag gaagagccag acttggaaaa gtacttgttt ccaggctctt
     1561 tcatcgagat ggagttcctc cataacaaga gcctttttaa agatatagcc tgtaaaaagt
     1621 gaaaggcaga gagctccaaa tggcatgaga agattggaaa ccaagaaatc catggcatca
     1681 aagaaagtct taccaaagat gtgaacatcc gccataactc cataggatag ggctgaagga
     1741 atgccaaaga caaaggtcaa aattcctaaa ataacactcc atttggcacg tttgctgtta
     1801 tcctggttgg tgatattgcc cacattgatc tccagcatca cgacagaaaa agtgactggc
     1861 gcaaaaagga agagcaagag gaaaaggacg tagaaaatgg ttccaaaagg catcttgtca
     1921 aagagttgag gcaagacgat aaagagcaag ctcggtcccc cttcagactg gatattgaag
     1981 ggggaccgag cttggaaaat ggctagacct gccatgatgg atatcgagat attcatggct
     2041 acgatggaga ttcctgactg gactaggttg gttttcttgt ccaagtaaga agcataggtc
     2101 aacatgactg taacccctag tgagagggca aagaaagatt gtcccagagc atagaggaga
     2161 ccagcgctag tcagttttga aaagtctggt ttgaggaagt aaagaacccc ttccatggca
     2221 tttggcaaac tgagagagcg accgatgata acaacaaaga tgataaagag caggggcatc
     2281 atgactttcg aagctctttc aatccctttt tgaaccccac gtgatacaat aaagatattt
     2341 aataagataa aggctgcttg agctcctagg gcaatggctg gatttgaaat gattgaagta
     2401 aataactgag cataatcacc cgttccacca agttggaaca atttcccaaa ctcaatacct
     2461 agatagacta gaatccatcc tccgataaca ctgtaaaaag ataagaggat aaagagggca
     2521 aaggcgccaa tccaaccgat aaagttgtac ttgttattct tgcccagttt tccaaaggtt
     2581 ttgatagcgg aaacgccagc actacggcca agggcaaact cagccagcag gagagggaaa
     2641 ccgattaaaa tagtggaaat gagaaagatt agtaaaaagc ctccatcgcc attagcagca
     2701 gtcatgtagg gaaacttcca aacggaacca agcccgatgg ccagccagca gatgctagaa
     2761 taaaaccaag tttcgacccc cattgtgatt tttctgacat agttaaactc tgatctcctt
     2821 tttcaaaata agaaaaagct acttgagttg tcaaatagcc ttctgtttga ttgatagact
     2881 tgactatcct atcatgtttt ctaaggtctg tcaagaaaat cattttcaag ttttcacacc
     2941 tttctcaaaa aagttaaaaa attttctcaa aaacgcttga ctctgaccta aggggagggg
     3001 ttatactatc attgtaagga ggaaatcatg taccatataa aagaagctgc gcagctttca
     3061 ggtgtctctg tcaagaccct gcatcactat gacaagatag gactcttggt ccccttaaag
     3121 tcggaaaacg gctatcgaac ctacagtcaa gaggatttgg aacgccttca ggtcattctt
     3181 tactacaaat atctaggctt ttctttagag aaaatagcag agctgttaaa ggaagaaagg
     3241 acagatttat tgccccattt gactaggcag ttggactatc taactcgcga aaggcaacat
     3301 ctggatacct tgatttccac cttgcaaaaa actattcaag aacaaaaagg agaaagaaaa
     3361 atgaccattg aggaaaaatt cacgggattt agctatcaag acaatcaaaa ataccaccaa
     3421 gaagcggtag agaaatatgg tcaagaagtc atgggacaag cgctcgaacg ccaaaaaggt
     3481 cacgaagacg aggctacggc cgcctttaac caagtctttc aaactttggc acaaaatctt
     3541 caagttggtt tacctgcaac agcaaccgaa aaccaagagc aagcagccaa gctcttgcaa
     3601 gccattcgca cttatggatt tgactgctct attgaggtat tcggtcatat cggtaaaggt
     3661 tacgtctata acccagagtt taaggaaaac attgacaagt ttggttctgg aacagcccag
     3721 tacacgtcag atgccattgc agcttacgtt cagacaaatg cagaaaaaat aggctaggaa
     3781 tttcctagcc tattttttac ttcaaatcat aaagccagtc gtcaccgttt ttgtagtaaa
     3841 agaattcact gagatcttct tctagaaaca cacgaagcat atcagacata tcatcggttg
     3901 caagttttag atgagaaaga ttttcaaagt cctcccacca aactttccct tcgtctgaag
     3961 actggagttc accagtaaag tgttctgtct tgtaaaaaag gacgacataa cgataatcct
     4021 tgtcgtcata ccagtttttg ataccacaga gttggggttt ggaaatgatc agaccagttt
     4081 cttctttcac ttcacgaatg acagcatcga caaaggattc gccacgttca acatgaccac
     4141 caggaaaagt aatgccaggc cagtcgggac taactcggtc ttggaccagg accttatctc
     4201 cgtttttaat catacacatg ttaacaaatt cgactgcctc tcttctgttc attcttcaca
     4261 acctttaatc tttaatcata atgcagactt cccgccaccc agccggtaca gagggcagaa
     4321 gtgatgttaa agccacccgt gtgggcattg atatccataa cttcgcctgc aaagtggagg
     4381 ccaggtacca gcttactttc aagggtttta ggattgattt ccttgagact gactccaccc
     4441 ttggtaacaa aggactttgc aagggacatt tttccagtta caggaatttt aagttcttta
     4501 atggactgga caagctgttc tcgttccttt tcagtcagct gtttgacttt ttcaggatat
     4561 ccttgtacaa aaaattcggc caagcgttct ggtaacaagg tttttaaagc gtttttcaag
     4621 gatttttccc gattttcttc tagaaatgta accaagtcct tctcagaaag ttgaggcaaa
     4681 acatcgagtg agagaacctc cccacctttg acaaagctag acatgcgtag ggcagcagga
     4741 cctgacaaac caaagtgggt aaagagtaaa tcatgagtga tgacatgctt accataactt
     4801 agggtcacat cgtccaaaga aatcccttgt aaggctttat gtggaaaatc tgttaataaa
     4861 ggactttcag cagcctcaag atcggtgatg gtatgcttaa aatggcgagc aatctcgtga
     4921 ccaaaaccag tcgaaccagt cgaaggataa gacttaccac ctgttgtgac aatgagtttc
     4981 tcacaagtga aggtttgatc cgctgactta aggacaaact ggttatctac ttttttaaca
     5041 gaaacgattt ctatttgagt agcaacttga ccacctagtt cggtgatttt cttttccaaa
     5101 gcttcgataa tagtccgaga cttgtcactg gctggaaaga cgcgtccgtg gtcttcgacc
     5161 ttaagtttaa caccattttc tgtaaaaaag ttgatgatgt catgattatc gaactgggag
     5221 aaaacactgt aaagaaagcg tccgtttcca ggaattccag ctagcaggtt gtctaagcta
     5281 ccattgttgg tcacattgca acgtccccca ccagtcccag ctaatttttt tccaagtttc
     5341 cgattttttt cgatgaggag ggttttctgt ccataaaagc tactggaaat cgtagccatc
     5401 ataccagcag gtcccccacc gatgacaata gtatcaaaat gtttcatagc tctattgtac
     5461 cacaaaaaaa caagagatga tggtcacctc ttgtcaagaa tgcaattaat caatttcata
     5521 gcccatcagc aaaccgccct cttctgcata gaaactgcag agaccagagg ttggtagaat
     5581 tttaatatcc gcttgtggga aggtttcacg gattcgctct gagagctgtt gacaacattt
     5641 ttcgttattg cgttgggcca tgacaatacg gccaccagca tatccagctt ttactaactc
     5701 atcataggca gcttgaactg atttctttga tccccttgct ttttgtagca attcgagagt
     5761 cccagtttca ctagcttttc cgaccatacg aatgttgaga aggccaacga ccgtaccgat
     5821 aagcttgctc aaacggccgt tcttcaccaa gttatcgact ttggctagga caaagagcaa
     5881 cttagttttt tcttgatagg cggtgatagc ttcaaccact tcttcaaaag acaagccctg
     5941 gtcaatcaag tcattcaatt tttctacgag taggtcaact tcaccaccag cagataaact
     6001 atcaatcaca tgaatcttag tgtcaggatg gtcttccaga taaatattct ttgctagttg
     6061 agcactattg tgactgccag aaagggtacc tgtgatggtt actaggaaaa tgtttttggc
     6121 accttcaaat gctcgcaaat agtcatctgg gcttggacaa gctgattttg aagcttctgc
     6181 agttgcatac atggtttcca tcatttggtc aatatcgaga ctggcgtcat caacaaagac
     6241 ctgatcagct acttgaatgg ttaaggggac acttacaaag gttgtgttaa tagctggtgt
     6301 tggcagttga cgataatcac aaccagagtc agcaataatc ttccaagtca tagaaattct
     6361 ccatctttgt cagttataca ttgacaaagg ttctgtcttt ttttacaatt atatcatgaa
     6421 aactcttgaa acaaaagcat catccgtctg ttgtgacaag tagaaagaaa atgttatgtc
     6481 tgaacgtaga atctctgaaa agtctcttga aaatctcaga aaatcaaatc aagaatccaa
     6541 tttattaacc agagaagcca ttgaaacagc cctcttgcaa ctcttggaaa aaaaggagct
     6601 gaccaagatt agtatttctg aattggtcaa acgtgcaggt gtttcgcgtg cggcctttta
     6661 tcgcaattat gactccaaag aggaaatttt agagagcgtc tttaaacgaa ctgtccacaa
     6721 tattatggaa cagctgcatc attacgattt aaagacagac ctttatttgg tttgggttca
     6781 ccttttccgg gaggccagaa aggaagctag agtaattcaa ttggccttgg attaccatct
     6841 ggaaaaaatc tttgtccaag ccatgcagga atttctagaa aaataccatg ggaaatcaaa
     6901 aggtgtcagc tcttatcttc attccttctg gagctcagcc atcgtctctg tccttctaaa
     6961 atggatcaag gatggcatga aggtaccagc tgaaaagatt gcagatttag gtttaccatt
     7021 ttttaaaaaa tagagaaaaa ggagaaaaga gatgactgaa aaaagactgg cctgggatga
     7081 gtattttgca gcccaagccc tactaattgc gaatcgttcc acttgtaaac gtgctaaagt
     7141 gggcgcgatt ctggtaaaag ataataaggt tatttccact ggttacaatg gttcggtgtc
     7201 agggactgag cattgtattg atcacgaatg tttggtcatt gaaggccact gtgttcgcac
     7261 ccttcacgct gaggtcaatg ctatccttca aggtgctgag cgtggtgttc ccaaaggctt
     7321 tacagcctat gtaacccatt ttccttgtct caactgtaca aaacaattgc ttcaggtcgg
     7381 ctgcaagcgc gtggtttata tcaaccagta ccgaatggac gactacgccc aataccttta
     7441 tcaagaaaaa gggacagaat tgacccattt accacttgag acagtacaga cagctcttaa
     7501 agaggctgat ctaatgtaaa aattatcaaa aataaatggt ttagaaagat ttttaaaccg
     7561 ttttttggta taatgagaag aataaattga aagaaggaat tccaaaaatg ggaaaaattg
     7621 aagttattaa tcacccactg attcaacaca aattgtcaat cttgcgtcgt acagatactt
     7681 ctacaaaagc ttttcgtgag ctagtagatg agattgcaat gttgatgggg tatgaagtac
     7741 ttcgtgatct tccactagaa gatgtggaaa tcgaaacacc aattacaaaa acagttcaaa
     7801 aacaattggc aggtaagaaa ttggccatcg tcccaatctt gcgtgcaggt atcgggatgg
     7861 ttgatggtct cttgagcttg gttccagctg ctaaagttgg ccacatcggt atgtaccgtg
     7921 atgaagaaac acttcaacca gttgaatact tggtgaaatt gcctgaggac attgaccaac
     7981 gtcaaatttt tgtagtagac ccaatgttgg caacaggtgg ctcagcaatc ttggctgttg
     8041 attctcttaa aaaacgtggc gcatcaaata tcaaatttgt ctgccttgta tctgctccag
     8101 agggtgtaaa agcccttcaa gaagctcatc cagatgtaga aatctttaca gcagccttgg
     8161 atgaacgttt gaacgaacac ggttatatcg ttccaggtct tggagatgct ggagaccgct
     8221 tgttcggtac aaaataagat cgaaaagaag aatgacttgg aaaagtattt ccagtcacga
     8281 aaggaggttg ggtttttgtt tctgtctaat gaaagcagag caaaaatttg accttttttg
     8341 accaagatat tataatagtc ttatcttcag tcatttgacc aacaaaatta aaactcaaaa
     8401 ggagaaatga atgattcctg tagttattga acaaacaagc cgtggagaac gttcttacga
     8461 tatttactca cgtcttctca aagaccgcat cattatgctg acaggtccgg ttgaagacaa
     8521 tatggctaac tctgttattg cccaattgct tttcttggat gcccaagata gtacaaaaga
     8581 tatttacctt tatgtcaata caccaggtgg ttctgtttca gctggtttgg caatcgtaga
     8641 taccatgaac tttatcaagg cagatgtcca aaccattgtt atgggaatgg ctgcatctat
     8701 gggaacagtc atcgcatcaa gtggagcaaa aggcaaacgt ttcatgcttc caaatgctga
     8761 atacatgatt catcaaccaa tgggcggtac aggtggtggt acccaacaaa ctgatatggc
     8821 tatcgctgca gaacacttgc tcaaaactcg taataccttg gaaaaaatct tggctgaaaa
     8881 ttcaggtcag tcaatggaaa aagtccatgc agatgcagaa cgtgataact ggatgagcgc
     8941 ccaggaaaca cttgaatatg gctttattga tgaaattatg gccaacaatt cattgaacta
     9001 atgatgatag aaggcaaact cgactgggtt tgcttttttt ggtataatag ggagagattt
     9061 cttagaaaga ggatttatca tgtttgaaaa agtcaatcgc tctggcttga ttatctatct
     9121 ttactataat cgtgatgcca aaaaactgca ggattatgga gatattacct atcattccaa
     9181 gaaacatcgt tacttacaac tctatgttcc aactcaagaa gtggagcaat tggtcggacg
     9241 cttgagcaag gaaaaattta ttaaaaaagt tagagtttgt catatccaag agttggaaac
     9301 accctttgtg ggcaatcttt atcgatagga aaacgttatc atcgaaaaag ttcaaggaaa
     9361 acattgacaa ttttctgata attcggtata ttcttaacag actatttaag aaataaggag
     9421 acaaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg cgcttgcaag tgtagcactt
     9481 cttgcagcct gtggagaagt gaagtctgga gcagtcaaca ctgctggtaa ctcagtagag
     9541 gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag gttctttagc tgcatacgga
     9601 acagctgaac aaaaaggtgc ccaattggct gttgatgaaa tcaatgccgc aggtggtatc
     9661 gatggaaaac aaatcgaagt agtcgataaa gataataagt ctgaaacagc tgaggctgct
     9721 tcagttacaa ctaaccttgt aacccaatct aaagtatcag cagtcgtagg acctgcgaca
     9781 tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag caggtgttcc cttgatctca
     9841 ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt acctctttat tggaactttc
     9901 caagatagct tccaaggaaa aattatctca aactatgttt ctgaaaaatt aaatgctaag
     9961 aaagttgttc tttacactga caatgccagt gactatgcta aagggattgc caaatctttc
    10021 cgcgagtcat acaagggtga aatcgttgca gatgaaactt tcgtagcagg tgacacagac
    10081 ttccaagcag cccttacaaa aatgaaaggg aaagactttg atgctatcgt tgttcctggt
    10141 tactataatg aggctggtaa gattgtaaac caagcgcgtg gcatgggaat tgacaaacca
    10201 atcgttggtg gtgatggatt caacggtgag gagtttgtac aacaagcaac tgctgaaaaa
    10261 gcatcaaaca tctactttat ctcaggcttc tcaactactg tagaagtttc agctaaagct
    10321 aaagccttcc ttgacgctta ccgtgctaag tacaatgaag agccttcaac atttgcagcc
    10381 ttggcttatg attcagttca ccttgtagca aacgcagcaa aaggtgctaa aaattcaggt
    10441 gaaatcaagg atagccttgc taaaacaaaa gattttgaag gtgtaactgg tcaaacaagc
    10501 ttcgatgcag accacaacac agtcaaaact gcttacatga tgaccatgaa caatggtaaa
    10561 gttgaagcag cagaagttgt aaaaccataa tagaaaaatg ttgaaatagg gaatgagcct
    10621 ttgactcact ccctgtttcg atatttaata ctcttcgaaa atctcttcaa actgcgtcaa
    10681 cgtcgccttg gattatatat gtgactgact tcgtcagtct tatctacaac ctcaaagcag
    10741 tgctttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtataag
    10801 aacctatcaa aaagtgaggg aaaaccctcg gaattataaa tagaaagagt gaatcttatg
    10861 ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt acgcgctgtt agccctagga
    10921 tataccatgg tttacggaat tatcaagctc atcaacttcg cccatggtga tatttatatg
    10981 atgggagcct ttatcggtta tttcttgatc aattctttcc aaatgaattt ctttgtagcg
    11041 cttattgtag ctatgctagc gacagctatt cttggtgtcg tgattgagtt tcttgcttac
    11101 cgacctttgc gccactctac tcgtattgct gttttgatta cggctattgg ggtttctttc
    11161 ctattggagt atggaatggt ctatctggtt ggtgccaata cccgtgcctt ccctcaagcg
    11221 attcaaacag ttcgatatga tttgggacca attagcttaa caaatgtgca gttaatgatt
    11281 ttggccattt ccttgatttt gatgattttg ttacaagtca ttgtccaaaa gactaagatg
    11341 gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg cgcaattgat ggggatcaat
    11401 gtaaaccgta cgattagctt taccttcgct ttgggttctg ctcttgcggg tgcggctggt
    11461 gttctgattg ctctttatta taactctctt gagcctttga tgggggttac tccaggtctt
    11521 aaatctttcg ttgccgcagt acttggtggt atcggaatta ttcctggtgc ggctcttggt
    11581 ggctttgtga ttggtctatt ggaaaccttt gcgacagcct ttgggatgtc agatttccgt
    11641 gatgccattg tttatggaat cttgttgttg atcttgattg tccgcccagc tggtatcctt
    11701 ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa atttaaaagt taatattcta
    11761 tggttactcc ttttgttagc tggctatagc ttgattagtg tactggtttc agtcggagta
    11821 cttaatctat tctatgtaca gattttacaa caaattggaa ttaatattat tttggctgtt
    11881 ggtctcaact taatcgttgg tttttcagga caattttcac ttggtcatgc tggtttcatg
    11941 gcgattggtg cctatgcagc agctattatt ggttctaaat caccaaccta cggtgccttc
    12001 tttggagcta tgcttgtagg ggctttgctt tcaggagcag ttgccttact tgtcggcatt
    12061 ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa ctctgggtgt ttctgaaatt
    12121 atccgtatct ttatcatcaa tggtggaagt cttacaaatg gtgcggcagg tatcttaggg
    12181 attcctaact ttacaacttg gcaaatggtt tacttctttg tcgtgattac aaccattgca
    12241 accttgaact tcttgcgtag cccaattggc cgttcaaccc tctctgttcg tgaagatgaa
    12301 atcgctgctg agtcagttgg ggttaatacg actaaaatta aaatcatcgc ttttgtcttt
    12361 ggtgccatta ctgcaagtat tgctgggtca cttcaggcag gatttatcgg gtctgttgta
    12421 ccgaaagatt acaccttcat caactcaatc aacgttttga ttattgttgt atttggtgga
    12481 ctcggttcca ttacaggtgc gattgtttcg gctattgttc tgggaatttt gaatatgctt
    12541 ctccaagatg ttgctagtgt gcgtatgatt atttacgctt tggccttggt attggtaatg
    12601 attttcagac caggtggact ccttggaacg tgggaactga gcctatcacg tttctttaaa
    12661 aaatctaaga aggaggaaca aaactaatgg cattacttga agtaaaacag ttaaccaaac
    12721 attttggtgg tctaacagct gttggagatg tgactcttga attgaacgaa ggggaactgg
    12781 ttggattaat cggtccaaac ggagctggga aaaccaccct tttcaacctt ttgaccggtg
    12841 tttatgaacc aagcgaggga acagtaaccc tagatggtca ccttttgaat gggaaatcac
    12901 cttataagat tgcctctttg ggacttggac gtactttcca aaatatccgt ctttttaaag
    12961 atttaacagt tttagacaat gttttgattg cttttggaaa ccatcacaaa cagcatgttt
    13021 ttactagttt cttacgctta ccagcttttt acaagagtga aaaagaatta aaggctaaag
    13081 ctttggaatt gttgaaaatc tttgatttag atggtgatgc agagactctt gctaaaaatc
    13141 tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc ccttgctacg gaacctaaaa
    13201 ttctcttctt agatgaacca gcagcaggta tgaacccaca ggaaacagcc gaattgactg
    13261 agttaattcg tcgtatcaaa gatgaattta agattacaat catgttgatt gaacacgata
    13321 tgaatctggt catggaagta acagaacgta tctacgtact tgaatatggc cgtttaattg
    13381 ctcaaggaac tccagacgaa attaagacca ataaacgcgt tatcgaagct tatctaggag
    13441 gtgaagccta atgtctatgt taaaagttga aaatctttct gtgcattacg gtatgatcca
    13501 agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa gttgtttccc ttatcggtgc
    13561 caacggtgca ggtaagacaa ctattcttcg caccttgtca ggtttggttc gaccaagttc
    13621 aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg ccagctcaga aaatcgtggc
    13681 aggtggtctt tcacaagttc cagaaggacg ccacgtcttt cctggcttga ctgttatgga
    13741 aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa gaaaatcaag ctaacttgaa
    13801 gaaggttttc tcacgctttc ctcgtcttga agaacggaag aaccaagatg cagctactct
    13861 ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct cttatgtcaa caccaaaact
    13921 tcttctttta gatgaaccat caatgggact tgccccaatc ttcatccaag agatttttga
    13981 tatcattcaa gatattcaga agcaaggaac aaccgtcctc ttgattgaac aaaatgccaa
    14041 taaagcactc gcaatctctg accgaggata tgtattggaa acaggaaaaa tcgtcctatc
    14101 agggacagga aaagaactcg cttcatcaga agaagtcaga aaagcatatc taggtggcta
    14161 aaacaatcca gtggattgtt ttagtcggca gatgaagatt acgaagtaat catcaatata
    14221 gtccggggga cctttttagc cggtagattg agattgcaaa caaatctgca tctacattga
    14281 aagcttaatt tctaataatt gaaaaaatcg aatgaaaagt ttcttacctt cattcacaga
    14341 gctcgatttt agagctcttt ttgctagctt attcatactt ttctaaattt tgaaaaagaa
    14401 atgtaagcgt ttgatagatt tgcaaaaaga ttgtataata gggataagaa tagaaaagga
    14461 gaagtctcat ggcagttaaa gattttatga cccgcaaggt agtttatatt agtccagata
    14521 caacagtatc tcatgcagca gatttgatga gagagcaagg attgcaccgc ttgcctgtta
    14581 tcgaaaatga tcaattggtt ggtttggtga ctgagggaac cattgcacaa gcaagtccat
    14641 ctaaagcaac aagtctttct atctatgaga tgaattatct tctgaataag acaaaagtaa
    14701 aagatgtcat gattcgcgat gttgtcactg tctcaggcta tgctagtcta gaagatgcaa
    14761 cttatctgat gttgaaaaat aagattggta ttctccctgt cgtagataac catcaagtat
    14821 acggagttat tactgaccgt gacgttttcc aagcctttct tgaaattgca ggttatggcg
    14881 aagaagggat tcgtgtacgc tttgttacag aagatgaagt tggtgttctt ggaaaaatta
    14941 tttctttgat tgtagaagaa aatttgaata tctcccatac agtcaatatt ccgcgtaagg
    15001 atggtaaggt cattatcgaa gtgcaaatcg atggatcaat tgatttacca gccttgaaag
    15061 aaaaatttga agcaaatggt attcaagtgg aagaaatcgc tcgcacttca gcaaaagtct
    15121 tgtaagaagg gaagcccaaa ggcttctttt ttcatgaaaa ggggattaga gcaaaagatg
    15181 gaaagaaatg ataaaatatg ctataatgaa atgatgtaaa aaaggagtat ttatggacat
    15241 ttcagtaatt cgtcagaaaa ttgacgcaaa tcgtgaaaaa ttagcttctt tcagggggtc
    15301 tctttgacct cgaagggcta gaggaagaga ttgccatctt ggaaaacaag atgacagaac
    15361 ctgatttttg gaacgataat attgcggccc aaaaaacgtc gcaagaattg aatgaattaa
    15421 aaaacactta caataccttc cataagatgg aagagttgca ggatgaagtc gaaattttat
    15481 tggatttttt ggctgaagac gagtcagtgc atgatgaact ggtagcgcag ttagccgaac
    15541 ttgataagat aatgaccagc tacgagatga ctctactctt gtcagaacct tatgaccaca
    15601 acaatgccat cttggaaatc catccaggtt ctggtggtac tgaggcgcag gactggggtg
    15661 atatgttgct tcgtatgtat actcgttatg gtaatgctaa aggctttaaa gtggaagtgt
    15721 tggattacca agcaggtgat gaggctggta ttaagtcggt aactttatca tttgaagggc
    15781 ctaatgccta tggtctcctc aagtcagaaa tgggtgttca tcgcttagtg cgaatctcac
    15841 catttgactc tgccaaacgt cgccatacct ctttcacatc tgtagaagtg atgccagaat
    15901 tggatgatac tattgaagtg gaaatccgtg aagatgatat caagatggat accttccgtt
    15961 caggtggtgc cggtggacaa aacgtcaata aggtttcaac aggtgtacgt ttaacccaca
    16021 ttccaactgg aattgttgtc caatcaacag tggatcgtac ccagtatgga aatagagatc
    16081 gcgccatgaa gatgttgcag gctaagctct atcaaatgga gcaagagaag aaggctgcgg
    16141 aggtagattc tctcaaaggt gagaaaaagg agatcacttg gggaagtcaa atccgttctt
    16201 atgtcttcac gccttatact atggtaaaag atcaccgaac tagctatgag gttgctcagg
    16261 tagataaggt tatggatggg gacctagatg gttttatcga tgcttatctc aagtggcgaa
    16321 ttagctaaga tagaaaggaa ctcacatgtc aattattgaa atgagagatg tcgttaaaaa
    16381 atacgacaac ggaacgactg ctctacgcgg tgtttcggtt agcgttcaac cgggggaatt
    16441 tgcttacatc gtaggacctt caggagcagg gaagtcaact tttattcgtt ctctgtatcg
    16501 tgaagtaaaa atcgataaag gaagtctatc agttgctggt tttaatctgg ttaagatcaa
    16561 aaagaaagat gtcccgcttc tacgtcgtag tgttggggtt gtcttccaag attataaact
    16621 gttaccaaag aaaactgtct atgaaaatat tgcttacgct atggaagtaa tcggggaaaa
    16681 tcgccgtaat atcaaaagac gagtgatgga agttttggac ttggttggat tgaagcataa
    16741 ggttcgttct ttcccaaatg aactctcagg tggggagcaa cagcggattg cgattgcgcg
    16801 tgcaattgta aataatccca aagtattgat agctgatgag ccaacaggaa atctggatcc
    16861 ggataattca tgggaaatta tgaatctctt ggaacggatt aacctacaag gaacaactat
    16921 tttgatggcg actcataata gccagattgt aaataccttg cgccaccgtg tcattgccat
    16981 tgaaaatggc cgtgtcgttc gtgacgaatc aaaaggagag tatggatacg atgattagta
    17041 gattttttcg ccatttattt gaagccttaa aaagtttgaa acgaaatggt tggatgacag
    17101 tagctgctgt cagttcagtc atgattactt tgaccttggt ggcaatattt gcatctgtta
    17161 ttttcaatac agcgaaacta gctacagata ttgaaaataa tgtccgtgta gtagtttata
    17221 tccgaaagga tgtggaagat aatagtcaga caattgaaaa agaaggtcaa actgttacaa
    17281 ataatgacta ccacaaggta tatgattctt tgaagaacat gtctacggtt aaaagtgtta
    17341 ccttttcaag taaagaagaa caatatgaaa aattaaccga gataatggga gataactgga
    17401 aaatctttga aggagatgcc aatcctctct atgatgccta tattgtagag gcaaacactc
    17461 caaatgatgt aaaaactata gccgaagatg ctaaaaaaat tgaaggtgtc tctgaggttc
    17521 aagatggcgg tgccaataca gaaagactct tcaagttagc ttcatttatc cgtgtttggg
    17581 gactagggat tgctgctttg ttaattttta tcgcagtttt cttgatttca aataccattc
    17641 gtattaccat tatttcccgc agtcgcgaaa ttcaaatcat gcgcttggtc ggagctaaaa
    17701 acagttatat ccgtggaccg ttcttgttag aaggagcctt tatcggttta ttgggagcta
    17761 tcgcaccatc tgttttggtc tttattgttt atcaaattgt ttaccaatct gtcaacaaat
    17821 cgttggtagg gcaaaatcta tccatgatta gtccagattt atttagtccg ttgatgattg
    17881 ccctactatt tgtgattggg gttttcattg gttcattggg atcaggaata tccatgcgcc
    17941 gattcttgaa gatttaggta aaatagctgc ttttatgagg agattgtaaa atctcctttt
    18001 ttgctacaag agtttttgaa aagagatgcg cagaagaaaa gagcttccaa agaagtcccc
    18061 cagagaagac ttcttgatgg ctaatttgaa cttgaaattt ggcgcactag aaatttttta
    18121 gaaaaaagtg taattttttt ataaaagcct ttacaaaaaa aattaaagtg gtataattaa
    18181 atcatagaaa gtgcaaacgt tttcgtaaaa cgtttgccta aataaaaata aaggagattt
    18241 gaatgatgaa agatacattc aaaaatgtct tgtctttcga attttggcaa aaattcggta
    18301 aggctttgat ggtagttatc gcggttatgc cggctgctgg tttgatgatt tcaatcggta
    18361 agtctatcgt gatgattaac ccaacctttg caccacttgt catcacaggt ggaattcttg
    18421 agcaaatcgg ttggggggtt atcggtaacc ttcacatttt gtttgcccta gccattggag
    18481 gaagctgggc taaagaacgt gctggtggtg ctttcgccgc tggtcttgcc ttcatcttga
    18541 ttaaccgtat cactggtaca atctttggtg tatcaggcga tatgttgaaa aatccagatg
    18601 ctatggtaac tactttcttt ggtggttcaa tcaaagttgc tgattacttt atcagtgttc
    18661 ttgaagctcc agccttgaac atgggggtat tcgtagggat tatctcaggt tttgtagggg
    18721 caactgctta caacaaatac tacaacttcc gtaaacttcc tgatgcactt tcattcttca
    18781 acgggaaacg tttcgtacca tttgtagtta ttcttcgttc agcaatcgct gcaattctac
    18841 ttgctgcttt ctggccagta gttcaaacag gtatcaataa tttcggtatc tggattgcca
    18901 actcacaaga aactgctcca attcttgcac cattcttgta tggtactttg gaacgtttgc
    18961 tcttgccatt tggtcttcac cacatgttga ctatcccaat gaactacaca gctcttggtg
    19021 gtacttatga cattttaact ggtgcagcta aaggtactca agtattcggt caagacccac
    19081 tatggcttgc atgggtaaca gaccttgtaa accttaaagg tactgatgct agtcaatacc
    19141 aacacttgtt agatacagta catccagctc gtttcaaagt tggacaaatg atcggttcat
    19201 tcggtatctt gatgggtgtg attgttgcta tctaccgtaa tgttgatgct gacaagaaac
    19261 ataaatacaa aggtatgatg attgcaacag ctcttgcaac attcttgaca ggggttactg
    19321 aaccaatcga atacatgttc atgttcatcg caacacctat gtatcttgtt tactcacttg
    19381 ttcaaggtgc tgccttcgct atggctgacg tcgtaaacct acgtatgcac tcattcggtt
    19441 caatcgagtt cttgactcgt acacctattg caatcagtgc tggtattggt atggatatcg
    19501 ttaacttcgt ttgggtaact gttctctttg ctgtaatcat gtactttatc gcaaacttca
    19561 tgattcaaaa attcaactac gcaactccag ggcgcaacgg aaactacgaa actgctgaag
    19621 gttcagaaga aaccagcagc gaagtgaaag ttgcagcagg ctctcaagct gtaaacatta
    19681 tcaaccttct tggtggacgt gtaaacatcg ttgatgttga tgcatgtatg actcgtcttc
    19741 gtgtaactgt taaagatgca gataaagtag gaaatgcaga gcaatggaaa gcagaaggag
    19801 ctatgggtct tgtgatgaaa ggacaagggg ttcaagctat ctacggtcca aaagctgaca
    19861 ttttgaaatc tgatatccaa gatatccttg attcaggtga aatcattcct gaaactcttc
    19921 caagccaaat gactgaagta caacaaaaca ctgttcactt caaagatctt actgaggaag
    19981 tttactcagt agcagacggt caagttgttg ctttggaaca agtaaaggat ccagtatttg
    20041 ctcaaaaaat gatgggtgat ggatttgcag tagaacctgc aaatggaaac attgtatctc
    20101 cagtttcagg tactgtatca agcatcttcc caacaaaaca tgcttttggt attgtgacgg
    20161 aagcaggtct tgaagtattg gttcacattg gtttggacac agtaagtctt gaaggtaaac
    20221 catttacagt tcatgttgct gaaggacaaa aagttgcagc aggagatctc cttgtcacag
    20281 ctgacttgaa tgctatccgt gcagcaggac gtgaaacttc aacagtagtt gtcttcacaa
    20341 atggtgatgc aattaaatca gttaaattag aaaaaacagg ttctcttgca gctaaaacag
    20401 cagttgctaa agtagaattg taatatactt gaggttggaa gctgtattcc aacctcttat
    20461 tttgggagaa aagaatgaaa tttttaacac tcaatactca tagttggatg gagaaagaag
    20521 cagaggaaaa attccagatt ttgcttgaag atattcttga aaaggactat gatttgattt
    20581 gtttccaaga aattaatcag gagatgacct cgtcagaggt ggaggttaat gacctttatc
    20641 aagctttgcc agcagctgag cctattcacc aagatcacta tgttagactc ttggttgaaa
    20701 agttatctga gcaagggaaa aattactact ggacctgggc ctataaccat atcggctatg
    20761 accgctacca cgaaggtgtg gctatcttgt ctaaaacacc tattgaagcc agagaaattt
    20821 tggtttcaga tgtggatgat ccaacagact atcatactcg ccgtgttgcc ctagctgaaa
    20881 ctgtagtcga tggcaaggag ctagcagttg ccagtgttca tctctcttgg tgggataaag
    20941 gttttcaaga agaatgggca cgatttgagg ctgtcttgaa aaaattgaac aagccacttt
    21001 tactagctgg agattttaac aacccagcag gtcaggaagg ttaccaagct attttagcta
    21061 gtccattagg cttacaagac gcatttgaag ttgctcaaga gaaaagtggt agctatactg
    21121 ttccgcctga aattgatggc tggaaaggga acactgaacc ccttcgaatc gattatgtct
    21181 ttactaccaa agagttagcg gtggaaaatt tacatgtcgt atttgatggt aacaagagtc
    21241 cacaagtgag tgatcactat ggcttgaatg ctatgttaaa ctggaaataa taactgaaaa
    21301 gaggttggaa cta
//
LOCUS       DAVLZG010000030        21016 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLZG010000030 DAVLZG010000000
VERSION     DAVLZG010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.030"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            471..709
                     /locus_tag="VYO72_001148"
                     /pseudo
     CDS             471..709
                     /locus_tag="VYO72_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            853..2082
                     /locus_tag="VYO72_001149"
     CDS             853..2082
                     /locus_tag="VYO72_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1707535.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2102..4798
                     /gene="ppc"
                     /locus_tag="VYO72_001150"
     CDS             2102..4798
                     /gene="ppc"
                     /locus_tag="VYO72_001150"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1707536.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    4881..5098
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5211..6215
                     /locus_tag="VYO72_001151"
     CDS             5211..6215
                     /locus_tag="VYO72_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1707537.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6284..7150
                     /locus_tag="VYO72_001152"
     CDS             6284..7150
                     /locus_tag="VYO72_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707538.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7147..7905
                     /locus_tag="VYO72_001153"
     CDS             7147..7905
                     /locus_tag="VYO72_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707539.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            7995..9755
                     /gene="dnaG"
                     /locus_tag="VYO72_001154"
     CDS             7995..9755
                     /gene="dnaG"
                     /locus_tag="VYO72_001154"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1707540.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            9758..10867
                     /gene="rpoD"
                     /locus_tag="VYO72_001155"
     CDS             9758..10867
                     /gene="rpoD"
                     /locus_tag="VYO72_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1707541.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            10881..11210
                     /locus_tag="VYO72_001156"
     CDS             10881..11210
                     /locus_tag="VYO72_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1707542.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11325..12368
                     /gene="cpoA"
                     /locus_tag="VYO72_001157"
     CDS             11325..12368
                     /gene="cpoA"
                     /locus_tag="VYO72_001157"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1707543.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12384..13709
                     /locus_tag="VYO72_001158"
     CDS             12384..13709
                     /locus_tag="VYO72_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1707544.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            13740..13916
                     /locus_tag="VYO72_001159"
     CDS             13740..13916
                     /locus_tag="VYO72_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1707545.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            13975..14109
                     /locus_tag="VYO72_001160"
     CDS             13975..14109
                     /locus_tag="VYO72_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1707546.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14173..15483
                     /gene="obgE"
                     /locus_tag="VYO72_001161"
     CDS             14173..15483
                     /gene="obgE"
                     /locus_tag="VYO72_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1707547.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15493..15651
                     /locus_tag="VYO72_001162"
     CDS             15493..15651
                     /locus_tag="VYO72_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707548.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            16701..17960
                     /locus_tag="VYO72_001163"
     CDS             16701..17960
                     /locus_tag="VYO72_001163"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1707549.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            17976..18527
                     /locus_tag="VYO72_001164"
     CDS             17976..18527
                     /locus_tag="VYO72_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707550.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18520..19797
                     /locus_tag="VYO72_001165"
     CDS             18520..19797
                     /locus_tag="VYO72_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1707551.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            19813..20673
                     /locus_tag="VYO72_001166"
     CDS             19813..20673
                     /locus_tag="VYO72_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1707552.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         6422 a         3615 c         4723 g         6256 t
ORIGIN      
        1 taaaagttaa gataattggt gcttctaaaa ctggcaatcc aaatgtttct ataattaatc
       61 aagaataact tttccgagag atattaaaac catcaataaa atagagcgat actttatatg
      121 ccatgataca aatgatatac aatgatactt ctgaccgttc aggctgccat cgtaaaagag
      181 cagcaagtga aattcttatg atgacttcat cagtcatgcc acgttaaatg tgtgagtttg
      241 ttagagaaac gcaattaatc ctcaaaaggt tccccgaacc ttttgagttc cacagacgca
      301 tcacgtggag tgtgtaagct tgttgctaaa agcgtaaaaa ccttggaacg aaaggaataa
      361 tagacttcct gcgaaacaaa aatacaatac aataaaacta tggatgatga agcaagtaaa
      421 caattaagcg atagccgttt caagagcctt gtaggtgttc agcgcacgag atgttagctg
      481 tgttaaaaac agcttatcaa cgcaacgtaa acgcgcaaaa ggtggacgaa aaaccaaatt
      541 aagcctagac gatctcctca tggtaactat tcaatacatg cgagaatagc acacttatga
      601 acaaattgcg gctgattttg gcattcacga aagcaacata attagtcgga gtcaatggat
      661 tgaagcaact cttattcaaa atggttttac gatttcaaat tctgccttaa ttctgtaaaa
      721 acagtaaaat tcgaaggatt gtaaggtaag agtttttttc tttctgaaaa aatggtataa
      781 tagcaatcaa aactagaaaa taaaacggaa tttggaacag atttgtctgt atcctagtag
      841 agtggtgata ctatgaagat tagtaagagg cacttattaa attattccat cttgattccc
      901 tacttgcttt tatctatttt gggcttgatt gtggtctatt cgaccaccag tgctatttta
      961 attgaagaag gcaagagcgc cttgcagttg gttcgaaacc aaggaatctt ttggattgtt
     1021 agtttgatac tgattgcctt aatttataaa ttgagactag attttttgag aaatgagcga
     1081 ctaatcattt tagttatatt aatagaaatg cttttattgt tcttggctcg ttttattggt
     1141 atttccgtaa acggggcata cggttggatt tcggttgcag gaataactat tcagccagct
     1201 gagtacttaa aaatcattat tatttggtat ttagctcacc gattctccaa acagcaagaa
     1261 gaaatagcta cttatgattt tcaagttttg actcaaaatc aatggcttcc ccgtgctttt
     1321 aatgattggc gattcgttct cctagttctg attggaagtt tgggaatttt ccctgattta
     1381 ggaaatgcga ctattttagt cttggtttcc ttgattatgt atacagttag tggaatcgct
     1441 tatcgctggt tttcaaccat tctggcgctc gtatctgccg cttctgtctt tgtcttgacc
     1501 actatcagcc taatcggtgt tgagaccttt tcaaaaattc cagtatttgg ctatgtagcc
     1561 aagcgcttta gtgccttttt taatcctttt gccgatcgtg ctgatgcagg tcaccagtta
     1621 gctaattctt attttgccat ggtcaatggc ggttggtttg gtctaggtct tggaaactcg
     1681 attgaaaaac gaggttattt gccagaagct catacagact ttgtcttttc tatcgtgatt
     1741 gaagaatttg gctttgttgg tgccagtctt attttagctc tcttattttt catgattttg
     1801 cggattatct tggtcggtat ccgagcggag aatcctttca atgccatggt tgcactcggt
     1861 gtcggaggga tgatgttggt tcaggtattt gtcaatatcg gagggatttc gggcttgatt
     1921 ccatctacag gagtaacctt ccccttctta tcccagggtg gaaatagtct tctagtctta
     1981 tcagtggcag tagcctttgt cttaaatatt gatgccagtg aaaaacgcgc taaattgtac
     2041 cgagaattgg aaaatcaacc aatgaacctt ctgttgaagt aggataaaga aaggatagtt
     2101 tatgtctctt caaaaattag aaaattatag taataaaagt gttgtgcaag aagaagtctt
     2161 gattctaaca gaattactgg aagatattac taaaaatatg cttgccccag agacctttga
     2221 aaaaataata cagttgaaag aattatcaac gcaggaagat tatcaaggtc taaaccgtct
     2281 agtgactagc ttatcaaatg atgaaatggt ctatatttca cgctatttct ctatcttgcc
     2341 tcttttgatt aatatttcag aggatgtgga tttagcttat gaaatcaatc atcaaaataa
     2401 tattgatcag gactatttag gtaaattatc tacaacgatt aaattggtag cagaaaagga
     2461 aaatgccgtt gagatcctag aacacttgaa tgttgtccct gttttgacag cccatccaac
     2521 acaagtgcaa cgcaaaagta tgttggattt aacaaatcat attcatagtc ttttgcgtaa
     2581 ataccgtgat gttaagttgg ggttgattaa taaagataaa tggtacaatg atttgcgtcg
     2641 ttacatcgaa attatcatgc agacagacat gattcgtgag aaaaaattaa aagtgactaa
     2701 cgaaatcacg aatgctatgg aatattataa cagctccttt ttgaaagctg tacctcattt
     2761 gacgacggag tataagcgct tagcgcaagc gcatggtctg aatttaaaac aggctaaacc
     2821 aatcaccatg ggtatgtgga taggtggtga ccgtgatgga aatccatttg ttacagcaaa
     2881 gaccttgaag cagtctgcac tcactcagtg tgaagtcatc atgaactact atgataaaaa
     2941 gatttaccaa ctttatcgtg aattttctct ttcaactagc attgtcaacg tcagcaagca
     3001 agtcagagaa atggctcgtc aatccaagga taactcgatt taccgcgaaa aagagcttta
     3061 ccgtcgtgcc ttgtttgata ttcaatcaaa aattcaggca actaaaacct atctgattga
     3121 ggatgaagaa gttgggactc gttatgaaac cgccaatgat ttctacaagg atttgattgc
     3181 cattcgagat tctctactag aaaataaggg tgagtccttg atttcaggtg attttgtgga
     3241 attattgcag gcagtagaga tatttggttt ttacttagcg tcaattgata tgcgacaaga
     3301 ctctagcgtc tatgaagcct gtgtggcaga actcttgaaa tcagcaggaa ttcattctcg
     3361 ttatagcgag ttgagcgaag aagaaaagtg tgaccttctc ttgaaagaat tagaagaaga
     3421 tccccgaatt ctttctgcga ctcacgcaga aaaatcagaa ttattagcaa aagaattagc
     3481 tatttttaag acggctcgtg ttttgaaaga taagttggga gatgatgtca tccgtcagac
     3541 catcatttca catgcaacca gcctttctga tatgctagaa ttagctattc tgttaaaaga
     3601 agtaggactg gtggatacgg aaagggcgcg tgttcagatt gttccccttt ttgaaacaat
     3661 tgaagacttg gatcattcag aggaaacaat gagaaaatat ctttctctta gccttgccaa
     3721 aaaatggatt gactcacgaa ataactacca agaaatcatg cttggctact ctgacagtaa
     3781 taaagatggc ggttacctgt catcatgttg gaccctctac aaggctcaac aacaattgac
     3841 tgctattgga gatgaatttg gcgttaaggt taccttcttc catggtcgtg gtggtactgt
     3901 cggtcgtggt ggtgggccaa cctatgaagc cattacatct caaccgctca agtctatcaa
     3961 ggatcgtatc cgcttgacgg agcagggtga agtaattggg aataaatacg gtaacaaaga
     4021 cgccgcttac tataaccttg aaatgctagt atcggcagct attaaccgta tgattactca
     4081 gaagaagagc gataccaata ccccaaatcg ttatgaagcc attatggatc aagtagtgga
     4141 ccgtagttac gatatctacc gtgatttggt ctttggtaat gagcatttct atgattattt
     4201 cttcgagtca agtccaatca aggctatttc aagttttaat attggttctc gtccagccgc
     4261 tcgtaagact attactgaaa tcggtggttt gcgtgccatc ccttgggtat tctcatggtc
     4321 acagagtcgt gttatgttcc ctggatggta cggggttggt tcaagcttca aggaatttat
     4381 caataaaaat ccagagaata ttgctatctt acgagatatg taccaaaatt ggcctttctt
     4441 ccaatcgctt ctttcaaatg ttgatatggt tttgtcaaaa tcaaatatga atattgcttt
     4501 tgaatatgct aaactttgtg aagacgagca agttaaggcc atctatgaga ctattttaaa
     4561 tgaatggcaa gttactaaga acgttatctt ggctattgaa ggacatgacg aactcttagc
     4621 tgacaatcca tatctaaaag ctagtctgga ttaccgtatg ccttacttta atattctcaa
     4681 ctatattcag ttagagttga ttaaacgcca acgtcgtgga gaattgtcca gtgatcaaga
     4741 acgattgatt catatcacca tcaacggaat tgcgacagga ttgcgtaatt caggttgata
     4801 attttcaaga gtgaatgcta aaagtgaata tcaaaaaaat tctaatagac tattgacaag
     4861 tagtttaaaa atgatataat ttaaccattc agaaaagtaa tcatacaaac tttttagaga
     4921 gtctgtggta gctgaaaaca gataagtggc gatgatgaaa attgggctga atgctattta
     4981 gaatttgaaa ttataaaaat tcggtaagca caccttacag tgcatctcgt tattgcgaga
     5041 ctgagcgata gggaaattcc ctataattga ggtggtaccg cgcatcgacg tcctcacaca
     5101 agttttttgt gtgaggattt ttttgatgga ggttagtatg gaaagaaaac gatggcgtcg
     5161 cttgtttaga taagtgaaat atgttaaagg aaataaaaag gagaaacaga atgaaaaata
     5221 aacgtttaat tggaattatt gctgcattag cagtcttagt agcaggaagc ttgatttatt
     5281 cttcaatgaa taaatcagaa gctcagaata ataaggatga gaagaaaata accaagattg
     5341 gtgtgcttca atttgtgagc catccatccc ttgatttgat ttataaaggg atccaagatg
     5401 gacttgcaga agaaggatat aaagatgatc aagttaaaat tgattttatg aactcagaag
     5461 gtgatcaaag taaggttgcg acaatgagta aacaattggt tgcaaatggg aatgaccttg
     5521 tggttggtat tgcaacacca gcagcccaag ggttggctag tgcaacaaaa gacctaccag
     5581 ttatcatggc cgctattaca gacccaattg gtgctaactt ggttaaagat ttgaaaaaac
     5641 caggtggtaa cgttacaggg gtatctgacc acaatccagc tcaacaacaa attgaactca
     5701 tcaaggctct gacaccgaat gtgaaaacaa tcggagctct ttactcaagt agcgaagaca
     5761 attcaaaaac acaggttgaa gaatttaagg cttatgctga aaaagcaggt ctgacagtgg
     5821 aaacatttgc agttccttca acaaatgaaa ttgcctcaac tgtcactgtt atgactatca
     5881 aggtagatgc tatttgggtt ccaattgata acaccattgc atcaggattt ccaacggttg
     5941 tctctagcaa tcaaagttct aagaaaccaa tttatcccag tgcgacagct atggtagaag
     6001 taggtggttt ggcatcagtt gtaattgacc aacatgacct tggtgtggca acaggtaaaa
     6061 tgattgtgca agtcttgaaa ggtgcaaaac cagccgatac cccagtcaat gtcttttcaa
     6121 ctggtaagtc agtcatcaat aaaaaaatag cacaagaact aggtattact attcctgagt
     6181 ctgttctcaa agaagcagga caagtcatcg aataaataag gtagggagga ggagactctt
     6241 cccatttttt aaaaagatga atatagaaag gattaaataa aatatgattg tttccattat
     6301 ttctcaagga tttgtctggg ctattctagg tctgggaatc tttatgacat ttaggatttt
     6361 aaactttcca gatatgacga cagaaggttc cttccctctt gggggagctg ttgctgtcac
     6421 tttgataacc aaaggcgtga acccattttt agcgacactt gttgctgtag gagcaggttg
     6481 tttggctgga atggcagcag gccttcttta tacaaaaggg aagatcccaa ccttgctctc
     6541 agggattttg gtgatgactt cttgtcactc aatcatgctc ttgattatgg gacgtgcgaa
     6601 tttaggcctg cttggaacca agcaaattca ggatgttttg ccttttgatt cggatttgaa
     6661 tcaactcttg acaggtctca tctttgtgag cattgttatt gctctcatgc tctttttctt
     6721 ggacactaaa ctcggacaag cctatattgc tacaggggat aatcctgata tggctagaag
     6781 tttcgggatt catactggac gcatggagct catgggcttg gtcttatcaa atggtgtgat
     6841 tgcccttgca ggtgccctca ttgctcagca agaaggctat gccgatgtgt ctcgagggat
     6901 cggggttatc gttgtggggc ttgcaagttt gattattgga gaagttattt tcaagagttt
     6961 gagcttggca gagcgtttgg ttactatcgt tgtaggttct atcgcttatc aatttttagt
     7021 gtgggcagtt atcgcacttg gctttaatac aagttacctt cgtttataca gtgccttgat
     7081 tttagcagtc tgcctcatga ttccaacatt taagcaaaca atcttgaaag gagccaagtt
     7141 aagcaaatga cagcaattgt agaattaaaa aatgcaacca aaattgttaa aaatggcttt
     7201 gatgaagaaa agattatttt aaatgatgtt tccttagaaa tttttgaacg ggactttatc
     7261 acgattttgg gcggaaatgg tgctggaaaa tcaaccctct ttaacactat agcagggacc
     7321 ttatcactaa ctagtggaac tatccgtatt ttaggtgaag atctcactaa gttttcaccc
     7381 gagaagcgtg ccaagtacct gtctcgtgtc ttccaagatc caaagatggg gacagctccc
     7441 cgtatgacgg tcgctgaaaa tcttttaatc gccaagtttc gtggtgagaa gcgtggattg
     7501 ttaccacgac gcttgactag ctataaggat gaatttcagg caaccattga aaaagtagga
     7561 aatggtcttg agaaacactt gaatacaccg attgagttct tatcaggtgg acaaagacag
     7621 gctttgagtc tcttgatggc aaccttgaag cgacctgaat tactcctgtt agatgagcat
     7681 actgctgccc tggatccaaa gactagtgtt gctttgatgg aattgacaga tgaatttgtt
     7741 aagaaagatc agctaacagc ccttatgatt actcatcata tggaagatgc tctcaaatac
     7801 ggcaatcgct tgattgtcat gaaagaagga cggattatcc aagatttaaa ccaagaagaa
     7861 aaagcaaaaa tgaaaatctc tgattattat caactctttg aataaagtag ggaaaatgag
     7921 tgaaatggtt tacttttttt ctgaaataaa gtatactata taaagtaaac tatgataaca
     7981 tggaggtatt gtgtatggtt gacaaacaag tcattgaaga aatcaaaaac aatgccaaca
     8041 ttgtggaagt cataggagat gtgatttctt tacaaaaggc aggacggaac tatctagggc
     8101 tctgtccttt tcatggtgaa aaaacacctt ctttcaacgt tgtagaggac aagcagtttt
     8161 accactgttt tggttgtggt cgctcaggtg atgtctttaa attcatcgag gagtaccaag
     8221 gggttccctt tatagaggct gtccaaatct taggtcagcg tgtcgggatt gaggttgaaa
     8281 aaccgcttta tagtgaacag aagccagcct cgcctcacca agctctttat gatatgcacg
     8341 aagatgcggc taaattttac catgctattc tcatgacaac gactatgggc gaagaggcca
     8401 gaaattacct ttatcagcgg ggtttgacag atgaagtgct taaacatttt tggattggtt
     8461 tagcacctcc agaacgaaac tatctctatc aacgtttgtc tgatcagtat cgtgaagagg
     8521 atttactgga ttcaggcctg ttttatctct cggatgccaa tcaatttgta gacacctttc
     8581 acaatcgcat tatgtttccc ctgacaaatg accaaggaaa ggtcattgcc ttctcaggtc
     8641 gtatctggca aaaaacggat tcacaaactt ctaagtataa aaacagccga tcgactgcaa
     8701 tttttaacaa aagttacgaa ttatatcata tggatagggc aaaaaaatct tctggaaaaa
     8761 ctagtgagat ttacctgatg gaaggattca tggatgttat tgcagcctat cgggctggaa
     8821 tcgaaaatgc tgtggcgtcg atgggaacgg ccttgagtcg agagcatgtt gagcatctga
     8881 aaaggttaac caagaaattg gttcttgttt acgatggaga taaggctggg caagccgcga
     8941 tattgaaagc attggatgaa attggtgata tgcctgtgca aatcgttagc atgcctgata
     9001 acttggatcc tgatgagtat ctacaaaaaa atggtccaga agacttggcc tatctattaa
     9061 caaaaactcg tattagtccg attgagttct acattcatca gtacaaacct gaaaacagtg
     9121 aaaatctgca ggctcagatt gagtttattg aaaaaatagc tcccttgatt gttcaagaaa
     9181 agtccatcgc tgctcaaaac agctatattc atattttagc tgacagtctg gcgtcctttg
     9241 attataccca gattgagcag attgttaatg agagtcgtca ggtgcaaagg cagaatcgca
     9301 tggaaagaat ttccagaccg acgccaatca ccatgcctgt caccaagcag ttatcggcta
     9361 ttatgagggc agaagcccat ctactctatc ggatgatgga atcccctctt gttttgaacg
     9421 attaccgttt gcgagaagac tttgcatttg ctacacctga atttcaggtc ttatatgact
     9481 tgcttggcca gtatggaaat cttcctccag aagttttagc agagcagaca gaggaagttg
     9541 aaagagcttg gtaccaagtt ttagctcagg atttgcctgc tgagatatcg ccgcaggaac
     9601 ttagtgaagt agagatgact cgaaacaagg ctctcttgaa tcaggacaat atgagaatca
     9661 aaaagaaggt gcaggaagct agccatgtag gagatacaga tacagcccta gaagaattgg
     9721 aacgtttaat ttcccaaaag agaagaatgg agtaataatg gcaacaaaac aaaaagaagt
     9781 aacaacattt gacgtacagg tagcagaatt tatccgtaat cataagcaaa aagggacagc
     9841 aacagatgat gaaatcaatg caagtctggt tattcctttt accttggacg ctgatgggat
     9901 tgaagatctc ttgcaacgga ttcaggatgc agggatttct atcacagata acgaaggaaa
     9961 tccaagtgcg cgtgttctta gcaatgaaga agaaccagaa ctcagcgatg aggacttgat
    10021 tggatcaact tctgctaagg tcaatgaccc tgtccgtatg tacttgaaag aaataggggt
    10081 cgttcctctc ttgaccaatg aagaggagaa agagttggca ctggctgttg aagctggcga
    10141 tatcgaagcc aaacaacgtc ttgcggaagc caatcttcgt ttggttgttt ccattgccaa
    10201 acgctatgtc ggtcgtggca tgcagttcct tgacttgatt caagaaggaa atatgggctt
    10261 gatgaaggcg gttgacaagt ttgactattc taaagggttc aagttttcaa cttatgcaac
    10321 ttggtggatt cgtcaggcta tcactcgtgc tattgcggac caagctcgta ccatccgtat
    10381 cccagttcac atggttgaaa ctatcaataa attggttcgt gaacagcgga atctccttca
    10441 agaattgggg caagatccga caccagaaca gattgctgaa cgaatggata tgacacctga
    10501 taaggttcgt gaaatcttga agattgccca agaaccagta tctcttgaaa ctcctatcgg
    10561 tgaagaggac gatagccacc ttggagactt tatcgaagat gaagtgattg aaaatccagt
    10621 ggattatacg actcgtatcg tcttgcgtga gcaattggat gaaatcttag atactcttac
    10681 agaccgtgaa gaaaatgttc tgcgtctacg ttttggacta gatgatggaa aaatgcgcac
    10741 acttgaagat gtggggaaag tctttaacgt aactcgtgag cgtatccgtc agattgaagc
    10801 aaaggctttg agaaaactac gccaaccaag tcgcagcaaa ccgcttcgtg attttattga
    10861 agactaagag tgaggaaaat atggcttata cagaagagca aattgaaaac atcaaaacac
    10921 ggattttaac agccttggaa gaagtcatcg accctgagtt gggaatcgat attgtcaatc
    10981 ttggtttgat ctatgagatt cgttttgacg gtgacacagg gcaaacagag attgacatga
    11041 ctttgacaac tatgggttgt cccttagcag accttttgac agaccagatt tatgatgcta
    11101 tgatagaggt tccagaagta acggatactg aggttaaatt agtctggtat ccagcctgga
    11161 cagttgaaaa aatgagtcgc tatgcccgca ttgccctagg cattaagtaa acatataaaa
    11221 gcatgtgaga gactagagga aaagcgagga aatttcccct cttttcctct agtctctcct
    11281 ttcttttgct gattttattc aaagaaaatg atataatagt agttatggag aaaaagaaat
    11341 tacgcatcaa tatgttgagt tcaagtgaga aagtagcagg acagggagtt tcaggtgctt
    11401 accgtgaatt agttcgtctt cttcaccgtg ctgccaagga ccaattgatt gttacagaaa
    11461 atcttccaat cgaggcagat gtgactcact ttcatacgat tgattttccc tattatttat
    11521 caaccttcca aaagaaacgc tcagggagaa agattggcta tgtgcatttc ttgccagcta
    11581 cacttgaagg aagtttgaaa attccatttt tcttaaaggg aattgtgaaa cgctatgtat
    11641 tttcttttta caaccggatg gagcacttgg ttgtggtcaa tcctatgttt attgaggatt
    11701 tggtagcagc tggtattcca cgtgaaaaag tgacctatat tcctaacttt gtcaacaagg
    11761 aaaaatggca tcctctacca caagaagagg tagtcagact gcgcacagat cttggtctta
    11821 gtgacaatca gtttatcgta gtaggtgctg ggcaagttca gaaacgtaaa gggattgatg
    11881 actttatccg tctggctgag gaattgcctc agattacctt tatctgggct ggtggcttct
    11941 cttttggtgg tatgacagat ggttatgaac actataagaa aattatggaa aatcccccta
    12001 aaaatttgat ttttccaggc attgtatcgc cagagcggat gcgcgaattg tatgctctag
    12061 cggatctttt cttgttgcct agttacaatg agctctttcc tatgactatt ttagaagctg
    12121 cgagttgtga ggctcctatt atgttgcgtg atttagatct ctataaggtg attttggagg
    12181 gaaattatcg ggcgacagcg ggtagagaag agatgaaaga ggctattttg gaatatcaag
    12241 caaatcctgc tgtcttaaaa gatctcaaag aaaaggctaa gaatatttcc agagagtatt
    12301 ctgaagagca tctgttacaa atctggttgg acttttatga gaaacaagcc gctttaggga
    12361 gaaagtaaaa agtgaggtaa tctatgcgaa ttggtttatt tacagatacc tattttcctc
    12421 aggtttctgg tgttgcgacc agtattcgaa ccttgaaaac agaacttgaa aagcagggac
    12481 atgctgtttt tatctttacg acgacagata aggatgtcaa tcgctacgaa gattggcaaa
    12541 ttatccgcat tccaagtgtt cctttctttg cttttaagga tcgtcgcttt gcctaccgag
    12601 gttttagcaa ggcacttgaa attgctaaac agtatcagct agatattatc catactcaga
    12661 cagaattttc tcttggcctg ttggggattt ggattgcgcg tgaattgaaa attccagtca
    12721 tccataccta tcacacccag tatgaagact atgtccatta tattgctaag gggatattga
    12781 tccggccgag tatggtcaag tatctggtta gaggtttcct gcatgatgtg gatggggtta
    12841 tttgccctag tgagattgtc cgtgacttgc tatctgatta taaggtcaag gttgaaaaac
    12901 gggtcattcc tactgggatt gaattagcca agtttgagcg tccggaaatc aagcaggaaa
    12961 atttgaaaga actgcgtagt aaactaggga ttcaagatgg tgaaaagacg ttgcttagtc
    13021 tttcgagaat ctcctatgaa aaaaatattc aagcagtttt agcagccttt gctgatgttc
    13081 tgaaagagga agacaaggtt aaactggtag tagctgggga tggcccttat ctgaatgacc
    13141 tcaaagagca agcccagaac ctagagattc aagactcagt catctttaca gggatgattg
    13201 ctcctagtga gacggctctt tactataaag cggcggattt cttcatttcg gcatcgacaa
    13261 gcgaaacgca aggtttgacc tacttggaaa gcttagccag tggaacacct gtcattgctc
    13321 acggaaatcc ttatttgaac aacctcatca gtgataaaat gtttggagcc ttgtactatg
    13381 gagaacatga tttggctggt gctattttgg aagccctgat tgcaacacca gacatgaatg
    13441 agcatacctt atcagagaaa ttgtatgaga tttcagctga gaactttggg aaacgagtgc
    13501 atgagtttta tctggatgcc attatttcaa ataacttcca gaaagatttg gctaaagatg
    13561 atacggtcag tcagcgtatc tttaggacag ttttgtatct tccgcaacag gtggttgctg
    13621 tacctgtaaa aggatctaga cgcatgttga aggcttcaaa aacacagttg atcagtatga
    13681 gagactattg gaaagaccat gaagaataga aagaggaaca gctatgaaaa aaacaattaa
    13741 tgagaagcgg tcgtgataaa aagattgcgg gtgtttgtgc tggggtggcc cattatctgg
    13801 atatggatcc gactatcgtt caagtcattt ggggtgttct tacttgctgt tacggagctg
    13861 gaattgtagc ttacattatt ttatggatta tcgcaccagt agcaactgac tattgaaaac
    13921 tagctcaatt catgctaaga taatagaaaa tagaatgtaa cgaaggagag aaaaatggca
    13981 tttggagata atggaaatcg taaaaaaact atgtttgaga aaataacctt gtttatcgtg
    14041 attatcatgc tagtagcaag tttattggga atttttgcaa ctgcaattgg tgccctcagt
    14101 aatctataaa atagattcaa gaaaatttag tgactgggat ttcccagccc ttttttaaag
    14161 tgagaagaaa taatgagtat gtttttagat acagctaaga ttaaggtcaa ggctggtaat
    14221 ggtggcgatg gtatggttgc ctttcgtcgt gaaaaatatg tccctaatgg aggcccttgg
    14281 ggtggtgatg gtggtcgtgg aggcaatgtg gtcttcgttg tagacgaagg actacgtacc
    14341 ttgatggatt tccgctacaa tcgtcatttc aaggctgatt ctggtgaaaa agggatgacc
    14401 aaagggatgc atggtcgtgg tgctgaggac cttagagttc gagtaccaca aggtacgact
    14461 gttcgtgatg cggagactgg caaggtttta acagatttga ttgaacatgg gcaagaattt
    14521 atcgttgccc acggtggtcg tggtggacgt ggaaatattc gtttcgcgac accaaaaaat
    14581 cctgcaccgg aaatctctga aaatggagaa ccaggtcagg aacgtgagtt acaattggaa
    14641 ctaaaaatct tggcagatgt cggtttagta ggattcccat ctgtagggaa gtcaacactt
    14701 ttaagtgtta ttacctcagc taagcctaaa attggtgcct accactttac cactattgta
    14761 ccaaatttag gtatggttcg cacccaatca ggtgaatcct ttgcagtagc cgacttgcca
    14821 ggtttgattg aaggggctag tcaaggtgtt ggtttgggaa ctcagtttct ccgtcacatc
    14881 gagcgtacac gtgttatcct tcacatcatt gatatgtcag ctagcgaagg ccgtgatcca
    14941 tatgaggatt acctagctat caataaagag ctggagtctt acaatcttcg cctcatggag
    15001 cgtccacaga ttattgtagc taataagatg gacatgcctg agagtcagga aaatcttgaa
    15061 gaatttaaga aaaaattgtc tgaaaattat gatgaatttg aagagttacc agctatcttc
    15121 ccaatttctg gattgaccaa gcaaggtctg gcaacacttt tagatgctac agctgaattg
    15181 ttagacaaga caccagaatt tttgctctac gacgagtccg atatggaaga agaagcttac
    15241 tatggatttg acgaagaaga aaaagccttt gaaattagtc gtgatgacga tgcgacatgg
    15301 gtactttctg gtgaaaaact catgaaactc tttaatatga ccaactttga tcgtgatgaa
    15361 tctgtcatga aatttgcccg tcagcttcgt ggtatggggg ttgatgaagc ccttcgtgcg
    15421 cgtggagcta aagatgggga tttggtccgc attggtaaat ttgagtttga atttgtagac
    15481 taggagactg gtatgggaga taaaccgata tctttccgag atgcggatgg taattttgtt
    15541 tccgccgcag acgtttggaa tgaaaagaaa ttggaagaac tatttaatcg tctcaatcca
    15601 aatcgtgcct tgagattggc acgaactaaa aaggaaaatc catctcagta aagaagctaa
    15661 aaaatcccgt gcctcatcag acacgggatt ttgtggtacg acaggcatgt atagcaaact
    15721 gaatctggaa tagcacagca tatcttctaa aatattgtta taaattgatt tgaatttcaa
    15781 aattaaattg tttgattctt atctcaattt gttatagtat atctgatgtc aaagttctcg
    15841 gcgagtcaaa tagcgattcc caagcctgac tatcgtgagg tagcggatta aaatggtctg
    15901 gggatagacc gttttaagtc tgacgctgga aataagaatt gtcagaagaa gggatagcga
    15961 aatcgtggct ctacgaacag gaacgtgata ataaggcgta tatagcggat aagagggcct
    16021 caaactctaa agtccaaaaa ggtagtcgta acctatatgc gtaaatcacg agagtaattg
    16081 aattcgtact aagattttct attttcactg taagctttta acgtccttat atcttgtata
    16141 cacgaggaaa gatgtacgac ttatcccgtg aggtctatca ctataaagag aaaacgacag
    16201 atagaagtga tcctgagtca cggttatctt taaaatagat tgtctgatag gacggtatgt
    16261 ataaaacgct tctgtgaact gagagaaggg ggagaagttc ttgctaaaat ttagttgaac
    16321 agccgtattc cgatacttag ataagagatc tagtcttagc tcctactcag ttttagggga
    16381 taaaaaaggg gaaatagcga ttcgagaaag attatactct tcgaaaatct cttcaaatca
    16441 cgtcaatatc gccttgccgt atgtgtagga tactgactac gtcagttcca tctacaacct
    16501 caaaacagtg ttttgagcaa cctgcggcta gtttcctagt ttgatctttg attttcattg
    16561 agtattagta attcagttac taactcgtca actctgattt atccaataaa attgaaaagg
    16621 atggaaaaaa ggataaattt atgatatact ttattttgaa gaccttatta gaaatcttga
    16681 aagagtattg aaaacttaga atgagaaaaa ttgttatcaa tggtggatta ccactgcaag
    16741 gtgaaatcac tattagtggt gctaaaaata gtgtcgttgc cttaattcca gctattatct
    16801 tggctgatga tgtggtgact ttggattgcg ttccagatat ttcggatgta gccagtcttg
    16861 tcgaaatcat ggaattgatg ggagctactg ttaagcgtta tgacgatgta ttggagattg
    16921 acccaagagg tgttcaaaat attccaatgc cttatggtaa aattaacagt cttcgtgcat
    16981 cttactattt ttatgggagc ctcttaggcc gttttggtga agcgacagtt ggtctaccgg
    17041 gaggatgtga tcttggtcct cgtccgattg acttacacct taaggcgttt gaagctatgg
    17101 gtgccactgc tagctacgag ggagataaca tgaagttatc tgctaaagat acaggacttc
    17161 atggtgcaag tatttacatg gatacggtta gtgtgggagc aacgattaat acgatgattg
    17221 ctgcggttaa agcaaatggt cgtactatta ttgaaaatgc agcccgtgaa cctgagatta
    17281 ttgatgtagc tactctcttg aataatatgg gtgcccatat ccgtggggca ggaactaata
    17341 tcatcattat tgatggtgtt gaaagattac atgggacacg tcatcaggtg attccagacc
    17401 gtattgaagc tggaacatat atatctttag ctgctgcagt tggtaaagga attcgtataa
    17461 ataatgttct ttacgaacac ctggaagggt ttattgctaa gttggaagaa atgggagtga
    17521 gaatgactgt atctgaggac agcatttttg tcgaggaaca gtctaatttg aaagcaatca
    17581 atattaagac agctccttac ccaggctttg caactgattt gcaacaaccg cttacccctc
    17641 ttttactaag agcgaatggt cgtggtacaa ttgtcgatac gatttacgaa aaacgtgtaa
    17701 atcatgtttt tgaactagca aagatggatg cggatatttc gacaacaaat ggtcatattt
    17761 tgtacacggg tggacgtgat ttacgtgggg ccagtgttaa agcgaccgac ttaagagctg
    17821 gggctgcact agtcattgct gggcttatgg ctgaaggtaa aactgaaatt accaatatcg
    17881 agtttatctt acgtggttat tctgatatta tcgaaaaatt acgtaattta ggagcggata
    17941 ttagacttgt tgaggattaa accgtagagg tgtttatgaa tatttggacc aaattagcaa
    18001 tgttttcttt ttttgaaacg gatcgcttgt atttgcgtcc tttctttttt agtgatagtc
    18061 aggacttccg cgagatagct tcaaatccag aaaatcttca atttattttc ccaacgcagg
    18121 caagtctgga agaaagtcaa tatgcactgg ccaattactt tatgaagtcc cctttgggag
    18181 tgtgggcaat ttgtgaccag aaaaatcaac aaatgattgg ttctattaaa tttgagaagt
    18241 tagatgaaat caaaaaagaa gctgagcttg gctatttttt gagaaaagat gcttggtcgc
    18301 aaggatttat gacagaggtt gttagaaaaa tttgtcagct ttcttttgag gaatttggct
    18361 taaaacaatt atttatcatt acccaccttg aaaatgaagc tagccaaaga gttgctctta
    18421 agtctggatt tagtttgttc cgtcagttta agggaagtga tcgttacaca agaaaaatgc
    18481 gggattatct tgaatttcgg tatgtaaaag gagagttcaa tgagtaagca tcaggaaatt
    18541 ctaagctatt tggaggaatt accagtaggt aaaagggtca gtgttcgtag catttcgaat
    18601 catctaggag ttagtgatgg aacagcctat cgagctatta aagaagctga aaaccgtgga
    18661 attgtggaga cccgtcctag aagtggaaca attcgtgtta aatcccagaa agttgctata
    18721 gatagattaa cgtttgctga aattgcagaa gtgacttctt ctgaggttct ggctgggcaa
    18781 gaaggtttag agagagaatt tagtaagttt tcaattggtg ccatgactga acaaaatatc
    18841 ttgtcttacc ttcatgatgg ggggctcttg attgtcggag accgaacccg tattcagttg
    18901 ctagccttgg aaaatgaaaa tgcagttctg gttacagggg gatttcaggt tcatgatgat
    18961 gtgcttaaac tggccaatca aaaagggatt cctgttctaa gaagtaagca tgataccttt
    19021 accgtcgcta ccatgatcaa taaagccttg tcaaatgtcc aaatcaagac tgatattctg
    19081 acagttgaga aactttatcg ccctagtcat gagtatggtt ttctgagaga gacagataca
    19141 gttaaagatt atttggactt ggttcgtaag aatcgtagca gccgtttccc tgttatcaat
    19201 caacatcagg tcgttgttgg cgttgtaacc atgagagacg ctggtgataa atcaccaagc
    19261 acgacaattg ataaggttat gtctcgtagt ctatttttgg ttggattatc gacaaatatt
    19321 gccaatgtga gtcaacggat gatcgcagaa gactttgaaa tggtaccagt tgttcgaagc
    19381 aatcaaactt tgcttggcgt tgtgacgcga cgagatgtca tggagaagat gagccgttcc
    19441 caagtttcgg ctctaccaac tttttctgag cagattggac aaaagctctc ttatcaccat
    19501 gatgaagtag tcattacagt ggaacccttt atgctagaaa aaaatggagt tttggctaat
    19561 ggtgtattgg cagaaattct gacccacatg acccaagatt tagttgttaa tagtggtcgc
    19621 aatctcatta tcgagcagat gctgatctac tttttgcagg ctgttcagat agatgatata
    19681 ttgcgcattc aggcacggat tattcatcat acgagacggt cagctataat tgattacgat
    19741 atttatcatg gtcaccagat tgtttcaaaa gcaaatgtga ctgttaaaat taattagaaa
    19801 ctaggagaaa agatgataac attaaaatca gctcgtgaaa tcgaagctat ggacaaggct
    19861 ggtgattttc tagcaagtat tcatataggc ttacgtgatt tgattaagcc aggcgtagat
    19921 atgtgggaag ttgaagaata tgtccgccgt cgttgtaaag aagaaaattt ccttccactt
    19981 cagattgggg ttgacggtgc catgatggac tatccttatg ctacctgttg ctctcttaac
    20041 gatgaagtgg ctcacgcttt ccctcgtcat tatatcttga aagatggtga tttgctcaaa
    20101 gttgatatgg ttttgggagg tcccattgct aaatccgacc tgaatgtctc aaaattaaac
    20161 ttcaacaatg ttgaacaaat gaaaaaatac actcagagct attctggtgg tttagcagac
    20221 tcatgttggg cttatgctgt tggtacaccg tccgaagaag tcaaaaactt gatggatgta
    20281 accaaagaag ctatgtacaa gggtattgag caagctgttg ttggaaatcg tatcggtgat
    20341 atcggtgcgg ctattcaaga atacgctgaa agtcgtggtt acggtgtagt gcgtgatttg
    20401 gttggtcatg gtgttggccc aactatgcac gaagaaccaa tggttcctaa ctatggtatt
    20461 gcaggtcgtg gactccgtct tcgtgaagga atggtcttaa ccattgaacc aatgatcaat
    20521 acaggcgatt gggaaattga tacagatatg aaaactggtt gggcgcataa gaccattgac
    20581 ggtggattgt catgtcagta tgaacaccaa tttgtcatta cgaaagatgg acctgttatc
    20641 ttgactagcc aaggtgaaga aggaacttat taataaaaag tgaaaagact actggaagtt
    20701 tattttgata aaaaatccag tagatctttt cataataaaa cgcattgtat caagtgttag
    20761 gggctgatat catgcgtttt tctgctttta agattttttc caactttgtt tgtaagcgca
    20821 tcataacaaa gggtctagga ttcagggctc tcctcctata tactattagt aaagtaaaac
    20881 taagggagga tattttagtg tcgcagtcta ttgttcctgt agagattcca caatattgtc
    20941 gttttgattc taaaaagaga aatggaattc tgtttaacgt ttgtattgcc aatcttaaat
    21001 ttattttttt atatta
//
LOCUS       DAVLZG010000031        20825 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLZG010000031 DAVLZG010000000
VERSION     DAVLZG010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.031"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            115..3216
                     /locus_tag="VYO72_001167"
     CDS             115..3216
                     /locus_tag="VYO72_001167"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1707553.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVDQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3299..4306
                     /gene="pfkA"
                     /locus_tag="VYO72_001168"
     CDS             3299..4306
                     /gene="pfkA"
                     /locus_tag="VYO72_001168"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1707554.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4365..5870
                     /gene="pyk"
                     /locus_tag="VYO72_001169"
     CDS             4365..5870
                     /gene="pyk"
                     /locus_tag="VYO72_001169"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1707555.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6095..6388)
                     /locus_tag="VYO72_001170"
                     /pseudo
     CDS             complement(6095..6388)
                     /locus_tag="VYO72_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167986.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(6554..6779)
                     /locus_tag="VYO72_001171"
                     /pseudo
     CDS             complement(6554..6779)
                     /locus_tag="VYO72_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7627..8499
                     /locus_tag="VYO72_001172"
     CDS             7627..8499
                     /locus_tag="VYO72_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1707556.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8645..8989)
                     /locus_tag="VYO72_001173"
                     /pseudo
     CDS             complement(8645..8989)
                     /locus_tag="VYO72_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9132..9443
                     /locus_tag="VYO72_001174"
     CDS             9132..9443
                     /locus_tag="VYO72_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707557.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            9447..10163
                     /locus_tag="VYO72_001175"
                     /pseudo
     CDS             9447..10163
                     /locus_tag="VYO72_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(10293..11108)
                     /locus_tag="VYO72_001176"
     CDS             complement(10293..11108)
                     /locus_tag="VYO72_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1707558.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11105..12010)
                     /locus_tag="VYO72_001177"
     CDS             complement(11105..12010)
                     /locus_tag="VYO72_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1707559.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            12422..14551
                     /locus_tag="VYO72_001178"
     CDS             12422..14551
                     /locus_tag="VYO72_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1707560.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIADLEKEAEKFVCEGFATGKEALAGAVDI
                     LVEALSEDVTLRAMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYNFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNINTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKQIDTEREKVNLSLLAPNETD"
     gene            14538..14987
                     /locus_tag="VYO72_001179"
     CDS             14538..14987
                     /locus_tag="VYO72_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1707561.1"
                     /translation="MKLTDYVKQVSLEDFGRSFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            15046..15318
                     /locus_tag="VYO72_001180"
     CDS             15046..15318
                     /locus_tag="VYO72_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1707562.1"
                     /translation="MNSKFYKMRRNRMISGVLVGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15672..15863)
                     /locus_tag="VYO72_001181"
     CDS             complement(15672..15863)
                     /locus_tag="VYO72_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707563.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16291..17049
                     /locus_tag="VYO72_001182"
     CDS             16291..17049
                     /locus_tag="VYO72_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707564.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17051..19039
                     /locus_tag="VYO72_001183"
     CDS             17051..19039
                     /locus_tag="VYO72_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707565.1"
                     /translation="MFRLTNKLAISNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKKLGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTIFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQIINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19081..19725)
                     /locus_tag="VYO72_001184"
     CDS             complement(19081..19725)
                     /locus_tag="VYO72_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1707566.1"
                     /translation="MLRAGVLDANNGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKAPARTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(19751..20626)
                     /locus_tag="VYO72_001185"
     CDS             complement(19751..20626)
                     /locus_tag="VYO72_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1707567.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNCKRSVKKSSVTKELKEKILHYHNQ
                     KFSPDKKQASINFKPAGQSIEQRPEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENRNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKYLDYKSPREDFLM
                     ANLNLKFSVRNKSRN"
BASE COUNT         6358 a         3798 c         4402 g         6267 t
ORIGIN      
        1 aaaatacaaa tgaatagaaa ataaattagt aagctgatga aatttttctc aagagaagcc
       61 atttataggt gaaaatggta taatatagtg agaaggatag aggagaagtg taaattgatc
      121 gcacaactag atacaaaaac agtctatagt tttatggaaa gcgtcatttc gatcgaaaag
      181 tatgtgagag cagctaaaga atacggctac actcatttgg ctatgatgga tattgacaat
      241 ctttatggcg ctttcgactt tctagagatt acaaaaaaat acggcattca tcctttgcta
      301 gggcttgaaa tgacagtgtt tgtagatgat caggaagtga atttgcgttt tttagctcta
      361 tctagtgtgg gctatcagca gttgatgaag ctttcgacag ccaagatgca gggggagaaa
      421 acttggtcag tcctgtccca gtacctggag gatatcgcgg tcattgtgcc ttattttgat
      481 agagttgagt cgttagaact aggctgtgat tactatatag gggtttatcc agaaacacta
      541 gcaagcgaat ttcatcatcc tatcttacct ctttatcggg tcaacgcttt tgaaagcagg
      601 gatagagaag ttcttcaagt tttaacagcg attaaagaaa atctaccgct cagagaagtt
      661 cccttgcgtt cgagacaaga tgtctttata tcagcaagtt ctttagagaa actattccaa
      721 gagcgttttc cgcaagcttt ggacaattta gaaaagctta tttcaggcat ttcttacgac
      781 ttggatacta gtctgaaact gcctcgtttt aatccagcta gaccagcagt agaggagttg
      841 agagagcgtg ctgaactggg gcttgttcag aaggggttga ctagtaaaga atatcaagat
      901 agactagacc aagaattgtc tgttattcat gatatgggct ttgatgatta tttcttggtt
      961 gtttgggatt tgttgcgttt tggacgatcg aatggctatt atatgggaat gggaaggggt
     1021 tctgcagtag gcagtttggt ttcttatgcc ttagacatca cggggattga cccagtagag
     1081 aaaaatctga tttttgaacg ctttcttaat cgtgaacgct ataccatgcc tgatattgat
     1141 attgatattc cagatattta tcgtccagat tttatcagat atgttggtaa taaatatggt
     1201 agtaaacatg cggcacaaat cgttactttt tcaacctttg gagccaagca agctcttcga
     1261 gatgtcttga aacgctttgg tgtgccagag tatgaattat ctgcaattac taagaaaatc
     1321 agttttcgtg acaatcttaa gtcggcctat gagggcaatc tccagtttcg tcagcaaatc
     1381 aatagtaagt tagaatacca aaaagctttt gagattgctt gcaagataga gggctatcca
     1441 aggcaaacct ctgtccatgc ggctggtgtt gtaattagtg accaagattt aaccaactat
     1501 attcctctaa agtatggtga tgaaattcca ctgactcagt atgatgctca tggagttgag
     1561 gctagcggac ttttgaagat ggactttctg ggactacgaa atttgacctt tgtccagaag
     1621 atgcaagagt tgcttgctga aatagaaggt attcacctta aaattgaaga aatagatttg
     1681 gaagacaaag aaacgttaga tttatttgcc tctggaaata caaaaggtat ctttcaattt
     1741 gagcaaccag gtgccattcg tctgcttaag cgtgtgcaac cagtctgttt tgaagatgtc
     1801 gtcgcgacta cttctctaaa tcgaccgggt gctagtgact atatcaataa ttttgtggca
     1861 agaaagcatg ggcaggaaga agtgactgtt ctggatccag tactggagga tattttggct
     1921 ccaacctacg gcataatgct ctatcaggag caggttatgc aggttgccca gcgacttgcc
     1981 ggatttagtc ttgggaaagc cgatattttg cgtcgggcta tggggaaaaa ggatgcctct
     2041 gccatgcatg agatgagggc ttcctttatt caaggttcat tagaagctgg tcatactgtg
     2101 gaaaaagcag agcaggtctt tgatgttatg gagaagtttg caggttatgg ttttaacagg
     2161 tcacacgcct atgcctactc agccttggcc ttccagttgg cttatttcaa aacgcattat
     2221 ccagccattt tttatcaggt catgttaaat tcttccaaca gtgattactt aatagatgca
     2281 cttgaagcag gttttgaagt agcctctcta tccatcaaca ccattcccta tcacgataaa
     2341 attgccaaca aggccatcta tctaggtttg aaatccatta aaggagtcag taatgattta
     2401 gctctctgga ttattgaaaa tagaccttat tctaacattg aagattttat agctaaatta
     2461 cctgagaatt atctgaaact tcctctgcta gaacctttgg taaaagttgg tcttttcgat
     2521 tcatttgaaa aaaatcgtca aaaagtattt aataacttag ctaatctatt tgaatttgtg
     2581 aaagagttgg gaagtttgtt tggagatgct atttatagtt ggcaggaatc ggaagattgg
     2641 acggaacaag aaaaatttta tatggaacaa gagcttttag ggataggtgt cagcaaacat
     2701 ccactacaag ctattgcaag taaggctatt tacccgatta ccccaattgg aaatttgtca
     2761 gaaaatagct atgctattat cttggttgaa gttcagaaga taaaagtaat tcgtaccaaa
     2821 aagggtgaaa atatggcttt cttacaggtg gatgacagta agaaaaaatt ggatgttaca
     2881 ctcttctcag atttatatcg acaggttgat caggaagtaa gagaaggagc attctactat
     2941 atcaaaggga aagtccagtc acgtgacggt cgtctgcaaa tgattgcaca agaaataaga
     3001 gaagcagtgg ctgagcgctt ttggattcag gttaaaaatc atgactcgga tcaagagatg
     3061 tcacgtattt tagaccagta taaaggccca atcccagtca tcatccggta tgaagaggaa
     3121 cagaaaacca tcgtttctcc ccatcatttt gtagctaaat ctgatgaatt agaggcgaaa
     3181 ttgaatggaa tagttatgaa aacgatttat cgctaaaaat acggaaaata gaagaatttt
     3241 aaaatcaaat gtgatataat caagaagaat gttaaaagaa aaaggagcat aaaccaatat
     3301 gaaacgtatt gctgttttga ctagtggtgg agacgcacct ggtatgaacg ctgctatccg
     3361 tgcagttgtt cgtcaagcaa tttcagaagg aatggaagtg tttggtatct atgacggata
     3421 tgctggtatg gttgccggtg aaattcaccc cctagatgca gcttcagtag gagacatcat
     3481 ttctcgtggt ggtacttttc ttcactcagc tcgttatcca gagttcgctc aacttgaagg
     3541 gcaacttaaa gggattgagc aattgaaaaa acacggaatt gaaggtgtag ttgttatcgg
     3601 tggtgacgga tcttaccacg gcgctatgcg tttgactgaa catggcttcc cagctattgg
     3661 tcttccaggt acaatcgata acgatatcgt tggtactgac tttacaatcg gttttgacac
     3721 agcggttact actgccatgg acgctatcga taagattcgt gatacatcat caagtcaccg
     3781 tcgtactttt gtaatcgaag ttatgggacg taacgctggt gatatcgctc tttgggctgg
     3841 tattgcaact ggtgctgatg aaatcatcat ccctgaagca ggcttcaaga tggaagatat
     3901 cgtagcaagc atcaaagctg gttatgaatg tggtaaaaaa cacaatatca tcgtcttagc
     3961 tgaaggtgtg atgtcagcgg ctgaatttgg tcaaaaactt aaagaagctg gagatacaag
     4021 cgaccttcgt gtaacagaac ttggacatat tcaacgtggt ggttctccaa ctgcgcgtga
     4081 ccgtgttttg gcgtcacgta tgggtgcaca tgctgttaaa cttcttaaag aaggtatcgg
     4141 tggtgttgcg gttggtattc gtaacgaaaa aatggttgaa aatccaattc ttggtactgc
     4201 agaagaaggg gcattgttta gccttactgc agaaggtaag attgtggtta acaacccaca
     4261 caaagccgat attgagctat ctagcttgaa taagagcttg tcataattta caatttagtt
     4321 aataagacca aaaaggtcat atatataaag gagtcacaaa aatcatgaac aaacgtgtaa
     4381 agatcgttgc aactttgggt cctgcggtag aaatccgtgg tggtaaaaaa ttcggtgagg
     4441 atggatactg gggtgaaaaa cttgatgttg aagcttcagc taaaaacatt gctaaattga
     4501 ttgaagctgg tgctaacaca ttccgattca acttctcaca cggcgaccac caagaacaag
     4561 gtgagcgtat ggcaactgtt aaacttgcgg aaaaaattgc aggtaaaaaa gttggtttcc
     4621 ttcttgatac aaaaggacct gaaatccgta cagaattgtt cgaaggtgaa gctaaagaat
     4681 attcatacaa aactggtgaa aaaattcgtg ttgcaactaa acaaggaatc aaatcaactc
     4741 gtgaagtgat tgcgttgaac gttgctggtg ctcttgatat ctatgatgat gttgaagttg
     4801 gtcgtcaagt tttggttgac gatggtaaac ttggtcttcg tgtggttgct aaagatgatg
     4861 caactcgtga atttgaagtt gaagttgaaa acgatggtat catcgctaaa caaaaaggtg
     4921 tgaacatccc taacactaaa attcctttcc cagctcttgc tgaacgcgat aacgacgata
     4981 tccgtttcgg tcttgaacaa ggtatcaact tcatcgcaat ttcattcgta cgtactgcaa
     5041 aagatgtgaa cgaagttcgt gcaatctgtg aagaaactgg aaacggacat gttcaattgt
     5101 tcgctaaaat cgaaaaccaa caaggtatcg ataacttaga cgaaatcatc gaagcagctg
     5161 atggtattat gattgctcgt ggtgatatgg gtatcgaagt accgttcgaa atggttccag
     5221 tttatcaaaa aatgattatc aagaaagtca atgctgcagg taaagttgtt atcactgcaa
     5281 caaacatgct tgaaacaatg actgaaaaac cacgtgcaac tcgttcagaa gtatcagacg
     5341 tattcaacgc tgttatcgac ggaactgacg ctacaatgct gtcaggcgag tctgcaaacg
     5401 gtaaataccc actcgagtca gtaactacaa tggctacaat cgacaagaac gctcaagctc
     5461 ttcttaatga atacggacgt cttgattcag attcatttga gcgtaactct aagacagaag
     5521 taatggcttc tgctgttaaa gatgctacta gctcaatgga tatcaaattg gttgtaactc
     5581 ttactaagac aggtcatact gcacgtttga tttctaaata ccgtccaaat gctgacatct
     5641 tagcattgac atttgacgaa ttgacagaac gtggcttgat gttgaactgg ggtgttattc
     5701 caatgttgac agatgctcca tcttcaactg acgatatgtt cgaaatcgct gaacgtaaag
     5761 cggtagaagc aggtctcgtt gagtcaggcg atgatatcgt tatcgttgct ggtgtgccag
     5821 taggagaagc tgttcgcaca aacacaatgc gtatccgcac agtacgttaa gaaaaatata
     5881 aaaacctatc atatccagct ttagagcttg tgtgataggc tttttgtata gagggtaaga
     5941 aataggcaaa actttcataa tggattgata ctcttcgaaa atctcttcaa accacgtcag
     6001 cgtcgcctta ccgtactcaa gtacagcttg cggctagctt cctagtttgc tctttgattt
     6061 tcattgagta tgaaataaga tatgcacaaa ttgattagaa agtcaaatga atttctacaa
     6121 atgttttagc aatcgtaatg tacttgtcta gattcgatct gatatatttt cgatttaatg
     6181 atatggtatt taaaacctcc aaagtagctt actccattct tttacttacg tgagtgtaga
     6241 tgttatttac tgttttagcg tttttgtgtt ccactctaac cattatagca ttcttctcag
     6301 ctagtgtact aaggagtgtg tgcctgaaaa tatgggaact aaggggctgg tttatcggtt
     6361 tctctagttt agtatttgcc ttttgcaaag tgatcttaaa tgcctttctc taaatttaca
     6421 tatcactatt gtttaacaaa atctaatcta tcttaggtca cttattcttt ttttgaaatg
     6481 tagaatgaac tttttcaaag tttttcgaat cttttaaaat ctgtttgttt tatatcgcca
     6541 ttctccccct tttttaattc tccctatata gcctgacaac tttcccgatg gtacgaatat
     6601 ggttgctttc gtctaggtgg atgtcggagt attcgggatt gagttttttt gaggtagcct
     6661 tggcggagtt tcttgacata gttagtgccg tctacttgga agatgccgat ggtattatag
     6721 tcaatctgtg gggtattctt gataaatagg tagtcgctgt ttcttatctt tggctccatg
     6781 gacttgctga cgacataagc gattgggtcg tagtcgtctg ggataatgga aactccataa
     6841 ctaaatcgtc gtcctgcatc aagcggctac ctgcagagat aaactaccta acacgagagt
     6901 aagtagtctg tctgtagtcg tccagtctga tgatttttac gatacttcgt ttttctgatc
     6961 atacagttgc ctctcggcat aggtcagaac tttaccttgt ctgggtggtg cccgttggtc
     7021 gtagatagat tggatatcgc taggagaatc cttttgaact ggaggaaaga gggcatcaat
     7081 caagctactg aatactttaa ctaagtcaaa tatagtattt ttcttagtag acctaaccct
     7141 tttttcataa tttctaatgg tgtttttact tatacctatc ttagtaccca attcttattg
     7201 agtccaacca ttactagtct atattgtttt atagttgatt gagtttggaa tagtacgctg
     7261 tagctgctaa aacatttcta ggaattaatt tgcctttcct aatagagttg ttcatatctt
     7321 atttcaatct actatatttt tcacctctaa caatcgcaat ctcttcttta tccatgaacg
     7381 aaaacgcttt ctatctttgt aagtaaagca tcacacgaaa tccacgaaaa tgaaaacctt
     7441 tgttgtgttt tcgtaaaaaa tttgttgaca gagcacgaaa cgcctactat aattaaatca
     7501 agtttaagga aataacaaaa aaacaaatcg gagggaaaga cgatgaacac attaaatgag
     7561 aaagtaatca atatctgtaa agcagtagtt aaagaaactt taatccaaga catttaggag
     7621 aaagaaatga agaaatcaag aaaattagcc acattaggaa tctgttcagc cttgttttta
     7681 ggcttggctg cttgtcaaca acaacatgct acttctgagg ggacgaatca aaggcaaagc
     7741 agttcagcga aagttccatg gaaagcttca tacaccaacc taaacaacca ggtaagtaca
     7801 gaagaggtca aatctctctt atcagctcac ttggatccaa atagtgttga tgcatttttt
     7861 aatctcgtta atgactataa taccattgtc ggctcaactg gcttatcagg agatttcact
     7921 tcctttactc acaccgaata cgatgttgag aaaatcagtc atctctggaa tcaaaagaag
     7981 ggcgatttcg ttgggaccaa ctgccgtatc aatagttatt gtcttttgaa aaattcagtc
     8041 accattccaa agcttgaaaa gaatgaccaa ttgcttttcc tagataacga tgcgattgat
     8101 aaaggaaagg tctttgattc acaagataag gaagagtttg atattctatt ttcgagagtt
     8161 ccaactgagg caactacaga tgtcaaggtt cacgctgaaa agatggaaac attcttctca
     8221 caatttcaat tcaatgaaaa agctcgaatg ctgtctgtag tcttgcacga caatctggat
     8281 ggcgagtatc tgtttgtagg tcacgttggg gtcttagtac ctgctgatga cggtttctta
     8341 tttgtagaga aattgacttt cgaagagccc taccaagcga ttaaatttgc tagtaaggaa
     8401 gattgctaca agtatttagg caccaagtat gcggattata caggcgaggg actggctaag
     8461 ccttttatca tggataatga taagtgggtt aaactttaat agtgttatga tatgacagta
     8521 atcttaggat ttttatttct atttttgatg agttggtggg ttatttcaat cgttaatagc
     8581 cagaaaccac gcaaaaatga aacatttatt ggctatatcc aaagatacga tattgatggg
     8641 aatggctatc aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaaaac
     8701 tactttgaac aagagttact tcaacccatt ggctccgacg gattaagttg ctttcgtgaa
     8761 caccaaaatc agccgcaatt tcttcataag tgcggtattc tcgcacatat tgaagagtgg
     8821 ccataagaag gtcttctagg cttaatttag gttttcgtcc cccttttgtg tgtttaagtt
     8881 gataagcagt ttttaataca gctaacatct cttcaaaagt ggtgcgctga acaccaacaa
     8941 gacatttaaa tcgtgcatca gttagttgct tacttgcttc atcattcata gaactactat
     9001 accatatttt gtttcgcagg aagtctaatg ctaaaatctt atcagtgaga agatttctta
     9061 aagtttattc tttgtagttt catctgtatt agtacataat ttaacttaga gaaaatagga
     9121 ggactaatcg aatggaatta aaagatttta cagaaaaaga acaggaaatg attaagaaaa
     9181 ggcttacaat gtctaatatt agtgacaaag aaactactga gaagattctg gcgctagtac
     9241 cacaagactt gattaagcga atcccgtttt ttgtcagaaa acatgctaca acacgtacga
     9301 ttaaacgcat ttcaattgaa caccctgaac tctacgctgt agctcaaaca agtggtgaga
     9361 ttccagaaaa aaaacgcgaa gaattgcgtc agattatcac aactatcttt gaacaaaaga
     9421 tgaataagca tagtattaag tagagaatga aaaaatattt tattggcggt ttgggaagca
     9481 atgcctatca tagcaaggat tttctttaag aactagattc gcaggtctat tttctaaatc
     9541 catatgaaaa gcatcttcga gatgaaacag aattgaaatc atggtttaaa aatgagattg
     9601 tagaggaaga atctatctgt ctgataggtc attctattgg aggcgattta gctcgttatt
     9661 tcgcatcgga atttgaagaa gtaaagaaac tgattctttt ggatggtggc tatctagatt
     9721 tagataagat tttacctttg gatacagagt tagaggaaac taaaaattat atcaaatctc
     9781 aaattatttc ggacttagat gttcttactt ctaaagaaaa atctgaagca aagcattggt
     9841 cagaaaatat ggagaaagct gtaagacagt cctatcactg gaatgttgag tataatagat
     9901 atgagttggc tataaattat gaaaatatag aagcgatact ccgcctacgg agaaaaatac
     9961 aagcttttaa gagagaagtg ggagatacct tgtttattag tcctcgctat cctaatgaag
    10021 ctacatggag agaggaagcc ctaaaagaat tgccagacta ttttgatact atttttttag
    10081 aaaactttgg ccatgagctt tatactcaag cacctaaaga aatcgctagt ctaatgaatg
    10141 agtggctcgc ttattttcta tgagctactt gtattgctgg aaatggtata agatgaaaat
    10201 ctacaagtca ctaattttca tataacaaaa aaacgaacag gctctttttc tgttattcag
    10261 aagagaactt gttcgttttt atcttgattt tcttaaaaag ctctatatac atagggattt
    10321 tctggtttat cgactttggt aaagctgtcg atttccaagg ttggaaggtt ttgtttgagt
    10381 tctttatggt agtgattgac cagttttcct ttggctgtaa tccaggtgtt gttttcatac
    10441 tgccgggtat tgcccttggt cagcaatcca tagacaccag aatctgcgat acagtggata
    10501 atgccgaatc ggaacagaaa ttgactattg gcatgactgg ggtcgttata gacaaagcct
    10561 gtaaactgga ttgtcttgcc ctcaaattca tctggatagt cgtagatagc ctccatgact
    10621 tccatatagt tttcattagt gatctgaata ctatcttggg ataagtattt atccgccgcc
    10681 gttcgcattt ccttttcata ggctgatttt gaaaaataag aactagtatc tggtttcaaa
    10741 tattggcttg tagtcccttc acttgtctga atagctagat ccgttccttc cgataggggg
    10801 aaatgataac ctttagcaga aacggtctga gaatccaagc taacagttgg gaaagttaag
    10861 ccgatgacaa gtggaatagc cagaagagaa atactcgtca tcttggccaa tcggctgttc
    10921 agatgactgt gggttttgac ttgcttcatc cagatataca attgaacaat tgccaagata
    10981 aaggaaagca ccatggagat ataggccaga taggaatagt gcatgttgat gtactggttt
    11041 agtttgcccg acagatggag gtaaatagtc agttcaaaat agccagctaa aactaaaaat
    11101 cgaatcatag gatgactcca atcaagagag aataggctaa aacgaccaga gtcacaatcg
    11161 taatgaagtg actaataaat cgtgctttca agtaattttt catcatgaga atatttttga
    11221 tatccagcat tgggccaatg acgagaaagg ccagaactgg tgccaaaccg aaactcgaga
    11281 gtagagaagc acctataaag gcatccgcct cactacagag cgaaagaaga aaggctaaaa
    11341 gcatcaagag caggatagca aaaagaggag tcgcactgat agaggtcaga atccgagtcg
    11401 gaacgtagac ctgtattata gaagcaaaga ggcagccaaa taccaaataa cgccccgtat
    11461 caaaaaattc atcaatggcc tgcacaaaga cttgaaaaac tttttttgca gaactcaagt
    11521 aagaaaaatc atgctcatga caagccagac gattttcttt ctgaatcggt tcttgccaga
    11581 aaaatcctag aaaaattcct agtattacag ccacaagaat ggaacccaga gctcgtaata
    11641 gtgcgacatg gaaggagttg ccaaaggcag aataggtcgc aaaaagaaca atgggattga
    11701 taacaggtgc tgtcacaaga aaaggaacgg ccgtgtaact tggaaccttt ttttccagaa
    11761 aacgattgat gatggggacg attccacatt cacaagaagg gaaaagtata ccgacaaagg
    11821 tcccaaaaaa gattctcccc caacgatttc gagggagaaa atgataaacc ttgtcaggtg
    11881 tgatataaac ttcaatcagc cctgagacaa tgcttcctat cagaacgaag ggaagggctt
    11941 caatgataat ggagagaaaa atggctccag tttgaagtac actagatggg agttgttgaa
    12001 aagcagtcat ctagtttttc ttttctgctt tgactttttt ctctttgtca tcagggaaag
    12061 taacttgttt caaatcaggg agtttagcaa actcttcaaa catcttgtcc aagtcgtctc
    12121 gttttgtaaa tttgacagcc ataggtgtac ctcgattcta aattctacct ctattatact
    12181 attattttgc ggaaaaggga gttttttaat ttgttttcga tagttgatac acttcgaaaa
    12241 tctcttcaaa ccacgtcagc ttcgccttac cgtagtacgg ttactgactt cgtcagttct
    12301 atccacaacc tcaaaacagt attttgagca gcctgcggct agcttcctag tttgcttttt
    12361 gattttcatt gagtatgaaa aggattggag aaagccttcc agcttgtggt ataatagatt
    12421 tatggataaa aaatatgaaa aaatctctca ggatttggga gtgacgttaa agcaaattga
    12481 taccgttcta agtttgacag ctgaaggggc gactattccc tttatcgcgc gttatcgcaa
    12541 ggacatgact ggtagtctgg atgaggtggc gattaaggct attattgatt tggataaaag
    12601 tctgacaaat ctcaatgacc gtaaggaagc tgtcttagct aagattcaag aacaaggtaa
    12661 gttgaccaag gaattggaag aagctatctt agttgccgaa aaattagcag acgttgaaga
    12721 actctatctt ccttataagg aaaagcgtcg taccaaggca accattgccc gtgaagctgg
    12781 actctttcct cttgctcgtt tgattttgca gaatatagct gacttagaga aagaagctga
    12841 aaagttcgtc tgtgaaggat ttgcgactgg taaggaagct ttggctggtg cagttgatat
    12901 cttggtcgaa gccttatcgg aagatgtgac actgcgtgct atgacttatc aggaagtgct
    12961 gagacactct aaactcactt ctcaagtcaa ggatgaaagt cttgatgaaa aacaggtttt
    13021 tcagatttat tataattttt cagagacagt tggaactatg caaggctatc gtaccttggc
    13081 tctcaatcgt ggggagaaac ttggtgtctt gaagatcggt tttgaacatg cgacggaccg
    13141 tattcttgcc ttctttgcta ctcgtttcaa ggtgaaaaat gcttatattg atgaagttgt
    13201 tcagcaatcc gttaagaaaa aggtcttgcc tgctattgag cgtcgtattc ggacagaatt
    13261 aactgagaaa gctgaagagg gagctatcca acttttttct gacaatctgc gcaatctcct
    13321 cttggttgct ccattgaaag ggcgcgtggt tcttgggttt gacccagcct ttcgtacagg
    13381 tgccaagcta gctgtcgtgg atgcaacagg aaaaatgctg acaactcagg tcatctatcc
    13441 tgttaaacca gcatcagctc gtcaaatcga agaagccaag aaagatttag cagatttaat
    13501 tggtcaatac ggtgtagaga ttattgccat tggaaatgga acggccagtc gtgaaagtga
    13561 agcttttgta gcggaagttc tgaaagattt ccctgaagtc agctatgtta tcgttaatga
    13621 aagtggtgct tctgtctatt ctgccagcga acttgctcgt caggagtttc cagacttgac
    13681 cgttgaaaaa cgctctgcca tttctatcgc ccgtcgtttg caagatcctc ttgcggaatt
    13741 ggtcaaaatc gatcctaagt caattggtgt cggtcaatac caacacgatg tcagtcagaa
    13801 gaaactatct gagagtctgg actttgtcgt ggatacggtg gttaaccaag tcggtgtcaa
    13861 tatcaatacg gccagtccag ctcttctttc tcacgtggct ggactcaata aaaccatttc
    13921 tgaaaatatt gtcaaatacc gtgaggagga aggaaaaatc acttcacgct cccaaatcaa
    13981 gaaagttcct cgtttggggg ctaaggcctt tgaacaggca gctggtttcc ttcgtatccc
    14041 tgaaagtagc aatatccttg ataatacagg agttcaccca gaaaattacg ctgccgttaa
    14101 ggaactcttc aaacgcttgg acattaagga cctgaatgaa gaggcccaaa gcaaactcaa
    14161 gtcgctttca gtcaaggaaa tggcgcaaga gttagacctt ggtccagaaa ctcttaaaga
    14221 tatcattgca gatcttctca aaccaggtcg agatttccgt gattcctttg atgctccagt
    14281 tctccgtcaa gatgtcctag atatcaagga cttagtggtt ggacaaaagc tagaaggagt
    14341 ggtgcgtaac gttgttgatt tcggtgcttt tgttgatatc ggaattcatg aggacggtct
    14401 catccatatt tcccatatga gtcgcaagtt tatcaaacac cctagtcaag tggtggcagt
    14461 tggagatttg gtgagcgttt gggttaagca aattgatact gaacgtgaaa aagttaatct
    14521 gtctctccta gctccaaatg aaactgactg attacgtcaa gcaggtttca ctagaagact
    14581 tcggcagatc ttttatccat catgtccagt ggaataggcg tctacgttcg acaggtgggc
    14641 gatttttccc caaagatggg catttggatt ttaatcccaa ggtttatcag gaactggggt
    14701 tggacgtttt taggaaaatt gtccgacatg aactctgtca ttatcacctc tattttcaag
    14761 ggaaaggcta tcaacataag gatcgagatt ttaaggaact gttgaaagca gtggatggat
    14821 tacggtttgt accatccttg cccaatagta actccaagcc aatcaagctc tatcgttgcc
    14881 aatcctgcca gcaaacttat cagcgtaagc gaagaattga taccagacgc tatcgctgtg
    14941 gactttgtcg aggtaaattg ctactaataa atcagcctga ggactgatga aagccgagcc
    15001 tacccgtgat atactatgtc taacttagca gaaagaggaa atatcatgaa cagtaaattt
    15061 tataaaatga gacgaaatcg catgatttca ggagttttgg taggcctgtc agacaagtgg
    15121 aactttgatg ttacccttgt acgttttctg tttgccattt ttacagtcgc aaactttgga
    15181 cttggggtga ttatctatat catcctagct tctatcatgc caaccaagga agaaatcgaa
    15241 gcagaaatgt acggaacagg cccacgtaaa cgcaaagaag ctcaagccat tgacgataat
    15301 gaaggctggt tttggtgagg ttttacaaaa gatttggaat acgcaaaaag ctttaaatca
    15361 atagtctaaa ctgcttgatt taaagctttt ttacttttat actcaataaa aatcaaagtg
    15421 caaactagga agccagccgc aggctgtaat ttagtcggca atgtgaagtt aacatagttt
    15481 gcactttgat ttttgaatag tattaataat atttcgccag cttcatccac aaactatagt
    15541 ggattggaac tagaatagta cacctctact tctaaaatat tgttagaaat cgatttgact
    15601 atcctgatcg atttgtcctg tttttatttc attttattat aaaagcagta atttaaactc
    15661 agttttttaa tctatttttg ctgctgagac aatacatttt tggaaaaatg gtggatgctg
    15721 ataacaactg ataaccagca aataacataa gcagtgccgg taaattctgt accgataaag
    15781 tgtgtgtgtt caactaagag ctgaccgatg aatggagaga ggagatagag aagtccgatg
    15841 agtatatgtt ctttgtgttt cattaaagcg caccttcttt ccttataggt tgaacgactt
    15901 gcaagtgtta aattgaatgg tatgttatct aggtaagctt actcaaatga tagttcccgc
    15961 ttcctccttt tcaaagtaag ccttttcaca cttatgtttt acaactttaa aaataggaaa
    16021 tcaaatcatt ttctaagtaa ttttgcttat atttcaccca atcttacaaa aatgtaagat
    16081 taaagtctct tttgtaaggt taggttatgg caagcggtct ttttttgatg taaactagac
    16141 tcataaagaa caaaggagta acatcatgaa acaaatctta cataagaaaa ctagaaaacc
    16201 aagtcacaaa gaaattgagc gcgttcagct gggatgcact atgatgcaag ctacatttca
    16261 tttgatggga tattaagaaa ggagattctc atgacacttt tagatgtaaa acacgttcaa
    16321 aaaatttata aaacacgttt tcagggcaac caagtagaag ccctcaagga tattcacttt
    16381 accgtcgaaa agggtgacta cgttgccatc atgggtgagt ctggttctgg taaatcaact
    16441 cttctcaata ttctagctat gctggataaa ccaagtcgtg gtcaggttta cttgaatgga
    16501 actgacaccg caaccattaa aaattcacag gcctctagct tccgtcgtga aaagttgggc
    16561 tttgtcttcc aagactttaa cttgctagat actctatctg taaaggacaa tatcttgctt
    16621 ccgcttgtct tgtcaagaag acctattaca gagatgatga agaaattggt ggtgacagct
    16681 gagaatctgg gtattaacca attgcaagag aagtaccctt acgagatttc tggtggtcag
    16741 aaacagcgtg tagcagtagc ccgcgccatc atcacagaac ctgaaattct ccttgcggac
    16801 gagccaacag gagcccttga ttccaagtca tctgcagcct tacttgatgt ctttaatgaa
    16861 atcaatgagc gtgggcaaac catcctcatg gtaacccact caacagcagc tgctagcagg
    16921 gccaagcgtg ttctctttat caaagacggc attctttaca accaaatcta ccgtggagag
    16981 aagacagagc gtcagatgtt ccaagaaatc tctgatacct tgactgtcat ggcaagcgag
    17041 gtgaattagt atgtttcgat taaccaataa gttagcgata tcgaacctga ttaaaaaccg
    17101 caaactctac tatccctttg cactggctgt tctcttggca gtcaccatca cctatctctt
    17161 ttactcccta accttcaatc caaagattgc ggaaatccgt ggaggaacca ccattcaagc
    17221 aacacttgga tttggtatgt ttgtcgttac ccttgcgtca gccattatcg tcctctatgc
    17281 caatagtttt gtcatgaaaa accgttccaa gaaactgggt atatatggca tgttaggctt
    17341 ggagaagcgc catctaatca gtatgacctt taaggagtta gtgctatttg ggattctaac
    17401 tgttggagca ggaatcggta ttggagcctt gtttgacaag ttgattttcg ctttcctact
    17461 caaactgatg aaattgaagg tggaactggt cgctaccttc cagatgaaag ttgtcattac
    17521 agtacttctt gtcttcggtt tgattttcct aggcctcatg ttcctgaatg cccttcgaat
    17581 cgcccgtatg aatgccctcc agctctcacg tgagaaagct agcggagaga aaagaggtcg
    17641 tttcctacct ctccaaacta ttcttggttc cataagttta gggattggct attatcttgc
    17701 ccttacggta accgatcctc ttacagccct aacaattttc ttcctagctg ttttgctggt
    17761 tatctttggt acttatctat tgtttaatgc agggattaca gtcttcctac aaatcttaaa
    17821 gaaaaacaag aaatactatt accaacctaa taacctcata tctgtttcca acttgatttt
    17881 ccgtatgaag aaaaatgcgg ttggactagc aaccatcgct attttgtcaa caatggtttt
    17941 ggtaaccatg tcagcagcga caagcatttt caattccgca gaaagcttta aaaaagttct
    18001 aaatcctcat gattttgggg tttcagggca aaatgttgaa aaagaagatt tggacaaact
    18061 cttgagccag tttgcaagtg acaaaggtta tagtgtcaaa gagaaagaag tacttcgtta
    18121 cagtaacttt ggtattgcaa atcaagaagg aaccaagtta actatttttg aaaaaggaca
    18181 aaaccgtgtc caacccaaaa cagttttcat ggtatttgac caaaaagatt atgaaaatat
    18241 gactggtcaa aaactgtctc tatcaggaaa tgaggtcgga ctctttgcaa agaatgaggg
    18301 agttaaagaa cagaaagctc taactctaaa tgatcatcaa ttttctgtca aagaagaatt
    18361 tactaaagat tttattgtca accatgttcc aaatcagttt aatattttga ctgctgatta
    18421 caattacctt gttgtacctg atttacaagc ctttttgaac caattcccag attcggatat
    18481 ctataatcag ttttacggtg gtatgaatgt aagtatcagt gaagaagagc aactcaaagt
    18541 cgctgaagaa tatgaaaaat acttacaaaa gtttaatgct caattaaaca ctgaaggtaa
    18601 ctatgtgtat ggtagcactc tagcagatgc tagtgctcaa atgagtgtcc tctttggcgg
    18661 tgtcttcttt attggtattt tcctatccat tatctttatg gtcggaaccg ttctggtcat
    18721 ctactacaaa caaatttctg aaggctatga agaccgtgaa cgctttatta tcttgcagaa
    18781 agtcggttta gatcaaaagc aaatcaagca aatcatcaac aaacaggttt taactgtttt
    18841 cttccttcct ttgctttttg ccttcataca tctagccttt gcctaccata tgcttagcct
    18901 gattttaaaa gtgattggtg tactggatac gactatgatg ttgatcgtga ccttgtctat
    18961 ctgcgctatc ttcctcatcg cctatgtgct gattttcatg attacttcaa gaagttatcg
    19021 caagattgtg caaatgtaaa aaagatacct cgacttcaaa atcgaggtat ttcttgtatt
    19081 ctaaatgctg aaaagttgtt cgagcaggaa ggtaactccc atggtcaaga gaccaatagc
    19141 taggttccga atcatagctg ttctagccgg agcctttcca agtctggcac tagtgtaacc
    19201 agtgagaaga agggccacac cgacaataag gacagtagca gggatgcgat attcacttgg
    19261 gaatatggtc actgacagca ttggaggcaa acttctaagg aaaaaggcaa cgaagctaga
    19321 aatggcagcg tgccaaggat tggtaaattc ttcatactca atcccatatt tttcctctac
    19381 cagagccttg agtggatttt taagaaagat cttattagtc aagagttggg cagaagtttt
    19441 gcattctcca ttttggatat aagcagcata gagggatttt ttggctagtt ccctatcttg
    19501 gtctagcaag agtttttctc gcgaaacggc agcttcctcg gtatcttttg gagttgaaac
    19561 ggatacatat tctccaccag ccattgaaaa ggcaccagct aagatagccg caaaacctga
    19621 taaaaagata atccagatat tggtcgtggc actggcaact ccgataacca caccagcaat
    19681 ggaaataatt ccattgttag catcaagaac acccgcacgc aggatattta aacgacctgc
    19741 aaaatttgaa tcaatttcgt gatttgtttc tgacgctaaa tttcaagttc aagttagcca
    19801 tcaagaagtc ttctctgggt gacttgtagt ccaagtattt tttaggatag ttgttgatcc
    19861 acttttcgat gaatgcgact tctttgggag tcattttctt ggttccctta ggtaaccatc
    19921 tacgaatgag cctgttgcga ttctcattag ttcccctttc ccaagaggca taggggtgcg
    19981 cataatagat gtgctcctca gaaaatacat caaacaagcg attgaattcc gttccattat
    20041 ctgccgtgat ggaaagaatc ttgtgttgtt ttaagatgag ttttagagcc tgattgacca
    20101 cctcagcact tttatttgga atcaatcgga tgatctgatg tctacttttt cgatccgtca
    20161 agacaagcaa gcagtagttt ttcgctctcg taagtagaac cgtatcaatc tcataatgcc
    20221 cattctccaa gcgaaaattg atagcttcag gccgctgttc gatggattga ccagcaggtt
    20281 taaagttgat gctagcctgt ttcttatcag gcgaaaattt ttggttatga tagtggagaa
    20341 tcttttcctt tagttccttg gtcacgcttg atttcttgac cgagcgcttg caattgtttt
    20401 cataagactg ttgagcatag tcggcagaat aaacctcttt gaagcgccct tttccaagac
    20461 attgtcggac tgtcccacgc ttgatttcag tgtggatagt ttgaggaact tttccaagca
    20521 gagaggcaat ttctctattt gatttccctt cttttttcca tctttcgatt aagcgacggc
    20581 tatcgattgt caaatgtttg gcttttgtag tataattgtc ttgcatctct gtgcctttct
    20641 tgtgtttgtg gttgaacaac aagtataaca cagaggtgtt ttcttatgcc tacaagagct
    20701 atcagctagt tgaaccatct aatttttagg aggactgggt ggctaacttc attatagaac
    20761 tttcatttac gaacatatag taaaatgaaa caagaacaga acaaatcgat caggacagta
    20821 aaatc
//
LOCUS       DAVLZG010000032        20332 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLZG010000032 DAVLZG010000000
VERSION     DAVLZG010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.032"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(118..267)
                     /locus_tag="VYO72_001186"
                     /pseudo
     CDS             complement(118..267)
                     /locus_tag="VYO72_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(421..2052)
                     /gene="rlmD"
                     /locus_tag="VYO72_001187"
     CDS             complement(421..2052)
                     /gene="rlmD"
                     /locus_tag="VYO72_001187"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1707568.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2126..3100)
                     /locus_tag="VYO72_001188"
                     /pseudo
     CDS             complement(2126..3100)
                     /locus_tag="VYO72_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
     gene            complement(3174..3788)
                     /gene="pmp23"
                     /locus_tag="VYO72_001189"
     CDS             complement(3174..3788)
                     /gene="pmp23"
                     /locus_tag="VYO72_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1707569.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3788..4762)
                     /locus_tag="VYO72_001190"
     CDS             complement(3788..4762)
                     /locus_tag="VYO72_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1707570.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4770..6026)
                     /locus_tag="VYO72_001191"
     CDS             complement(4770..6026)
                     /locus_tag="VYO72_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1707571.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6088..6519)
                     /locus_tag="VYO72_001192"
     CDS             complement(6088..6519)
                     /locus_tag="VYO72_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707572.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(6521..7123)
                     /locus_tag="VYO72_001193"
     CDS             complement(6521..7123)
                     /locus_tag="VYO72_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1707573.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLSEISFEEA"
     gene            complement(7107..7946)
                     /gene="prmC"
                     /locus_tag="VYO72_001194"
     CDS             complement(7107..7946)
                     /gene="prmC"
                     /locus_tag="VYO72_001194"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1707574.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(7946..9025)
                     /gene="prfA"
                     /locus_tag="VYO72_001195"
     CDS             complement(7946..9025)
                     /gene="prfA"
                     /locus_tag="VYO72_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1707575.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9022..9612)
                     /locus_tag="VYO72_001196"
     CDS             complement(9022..9612)
                     /locus_tag="VYO72_001196"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1707576.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9736..9918
                     /locus_tag="VYO72_001197"
     CDS             9736..9918
                     /locus_tag="VYO72_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1707577.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10055..11428
                     /gene="mnmE"
                     /locus_tag="VYO72_001198"
     CDS             10055..11428
                     /gene="mnmE"
                     /locus_tag="VYO72_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1707578.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11475..12410)
                     /gene="dapA"
                     /locus_tag="VYO72_001199"
     CDS             complement(11475..12410)
                     /gene="dapA"
                     /locus_tag="VYO72_001199"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1707579.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12466..13542)
                     /locus_tag="VYO72_001200"
     CDS             complement(12466..13542)
                     /locus_tag="VYO72_001200"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1707580.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDMDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(13884..13956)
                     /locus_tag="VYO72_001201"
     tRNA            complement(13884..13956)
                     /locus_tag="VYO72_001201"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13921..13923),aa:Thr,seq:ggt)
     gene            complement(14056..14565)
                     /locus_tag="VYO72_001202"
     CDS             complement(14056..14565)
                     /locus_tag="VYO72_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1707581.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14563..14659)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14688..15119
                     /locus_tag="VYO72_001203"
     CDS             14688..15119
                     /locus_tag="VYO72_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1707582.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15201..15578
                     /gene="mscL"
                     /locus_tag="VYO72_001204"
     CDS             15201..15578
                     /gene="mscL"
                     /locus_tag="VYO72_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1707583.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15620..16714)
                     /gene="hemH"
                     /locus_tag="VYO72_001205"
     CDS             complement(15620..16714)
                     /gene="hemH"
                     /locus_tag="VYO72_001205"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1707584.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            16868..18091
                     /gene="pepT"
                     /locus_tag="VYO72_001206"
     CDS             16868..18091
                     /gene="pepT"
                     /locus_tag="VYO72_001206"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1707585.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18127..18459)
                     /locus_tag="VYO72_001207"
     CDS             complement(18127..18459)
                     /locus_tag="VYO72_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707586.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(18464..18757)
                     /locus_tag="VYO72_001208"
     CDS             complement(18464..18757)
                     /locus_tag="VYO72_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707587.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            18722..18943
                     /locus_tag="VYO72_001209"
     CDS             18722..18943
                     /locus_tag="VYO72_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707588.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19080..19289)
                     /locus_tag="VYO72_001210"
                     /pseudo
     CDS             complement(19080..19289)
                     /locus_tag="VYO72_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(19410..19552)
                     /locus_tag="VYO72_001211"
                     /pseudo
     CDS             complement(19410..19552)
                     /locus_tag="VYO72_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(19586..19726)
                     /locus_tag="VYO72_001212"
     CDS             complement(19586..19726)
                     /locus_tag="VYO72_001212"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1707589.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(19770..20330)
                     /locus_tag="VYO72_001213"
                     /pseudo
     CDS             complement(19770..20330)
                     /locus_tag="VYO72_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5872 a         4270 c         3839 g         6351 t
ORIGIN      
        1 gatactataa gcagcacacc aactatttat tttttgagtt ttaaactttg gtagaagtct
       61 tgaactcctt atatttacat aactatttgc ctctataact attatgacac gaaaccaaca
      121 agcaagttca agcacctcca tatctttatt caaatgagga ctaagatatt cacaaacttt
      181 atcataaacc tctttatctt ttttcataaa aggggcatac aacttagcaa atttatccta
      241 aaattttttg ttgcctttat caatcatttc aacactcctt taaatataaa aatgatccta
      301 tcaatcttta tattgagcct attttctaat tgataccttg caagaaagga ataatagctg
      361 ttcctatacc aagtaggaat gtaataaatg cagaaagtca tatactgtca ttcttttcta
      421 ttaaatcatt ttgaagtgtc tcaaagcatc catgatggct tcttcttttt caggtgtaca
      481 ctgtggaata atttgtttat cctttttaga cttgttgtaa tgttctcgta attctattcc
      541 acatttcttt tttatctgtg caatatataa tgtcgaaact tttaattcaa atttattcca
      601 aacatattct ttgatttgag catatgttgc tttgctctcc gcacttgtca aattcatctc
      661 atccagctca atttcaacac ttatgtgctt atcgacatcg agtttggaca aaagtgctac
      721 cgtctcgacg tgatgcgttt gaggaaatag atccaccggc tggactttct tcaattcata
      781 tcccaattct tggtagagtt tgatatcacg cgccatggtt gcgacattgc aggagatata
      841 ggcgatgcga tcggctcctg tttgggcgct tgctttgata aagctttctg tcaagccctt
      901 gcgtggagga tcaaccaaga taacggttgg ttgaatccca tctttaagcc aattcttcat
      961 agcattttca gctgtgtcac agacatagtg ggcgtttgaa atattgttca gctgagcatt
     1021 ttttttacta ttctcaaccg cttctggaat cagttcaaca ccgtagactt ctttgacatg
     1081 cttggcgact gataaaccaa tggttccaat accagaatag gcatcaataa tcacgtcatc
     1141 tttttttaac tctgcaaagt caatggctgt ttgatagagt ttctccgcca tttcagtatt
     1201 gacttggtaa aaggctgggc cagcgatttg gaagtcattt cccaacatct ggtccgtaat
     1261 atagtcttga ccataaagag tgcgccactc cttaccaaaa atcgcattgg tattctggtc
     1321 gttgatattt tgcatgacag acacaatctc tgggaactgc ttgataactt gttcaatcaa
     1381 ttggtcaaca cgaaaaactt ttggacgagt tgtcaccaaa acgaccatga tttgtcctga
     1441 atagtgacca cgacgcacca caagattccg aatcaatcca gactgttcct tttcgtcata
     1501 aggttttaaa tcaaaacgac ggagcaggtc tcgaagagct actacgactt ggtcaatgac
     1561 aggatcctgg ataaagaaat cttcaagggg catgaggttg tgcgaattct tacggaaaaa
     1621 tcctgtttcc aagacaccat tcactcgacg aacgggcacc tgcgccttat tgcgatactt
     1681 gactggatgt tccataccaa gcgtttcagc aacttctaca tctgcaattc cagcaatctt
     1741 gtagagactg tccttgactt gcttggtttt aaacttgagc tgttctggat aagaaaggtg
     1801 tcctaaatcc gcgattcctg aacgcaggta agccaaatct agatcttgat tacggtgtgg
     1861 tgactggaca aggtattttt caacttttcc aaagccaatc tttttattga ccttgaggac
     1921 acgcatgaga attttttcac tcggtaaagc attctctaca aaaaagacca aaccatctac
     1981 cttggcaact cctgcccctt catgggtcaa gtcaacaatt tcaacttcta caatatcatt
     2041 tttctttaac attcttttct ctttctattg gccgacaaaa aagacggcaa cgttacggtt
     2101 accatccatt ataccatgaa atttcttaag aaccaaaact cttgaagaag ttgacaaggg
     2161 cttgccagag ggagcttaag aagttaccac cgtcctctag cgccttatcc gcatcaaagt
     2221 taaggttgat atttttaaaa ctgtcgccag cttgtgatac gatgctttgt ttaaggtcat
     2281 ttagggtttt agtgaaatct gcattgctga ggatatcact ctttgagaga ttcaaggcaa
     2341 aattgatgat gatattgatc tagtttcctg ttatgacctg atcaagtttg taatttttta
     2401 aggtatcttc aacaatcttg cgtacatctt cttctgtcag atttcccttg ctttctttag
     2461 ctttggcgag tcctgacttg atatcagcta gggcaacgtt taatttatta gcatcatagc
     2521 ctgatttgtc cttgttttca gcattgatat ctgacaaagc ctttagctct tcttgagcca
     2581 aatctttatt ggcttgcggc accttggctc cattagcttc tagcgaatag tagatcccag
     2641 ccaaagcact ctcacctgta actggaatag gggctgctac agtgattttg gcatgttcca
     2701 tacccagcgt tactgctgcg tttcggtaca tatcctgagt caccttagtg atattttctg
     2761 gtgtttcaat cttgacctca agtggcgatt tgtcacctag cttttgaatc ttggctgatg
     2821 aatacaactg taagctagag tcattggcca cattcatgat tttagaataa acatcaggtg
     2881 tcatggtctt gagttctttg gtatctgttg aggcattgta gcccagtttt ttaagagttt
     2941 gatttttttg gtcttcagat agggaggaac ctaggacata ttcaggttgg acataggttt
     3001 catcgataac tttttgaaca tctgttgctg catgggcgct attcatagct gttactgccc
     3061 acaagaccgc agcactggtc agaaagagtt tctttctcat agggaatttc ctcctttact
     3121 tttctagagt aatatatcta tcttaaagaa aacttataac aaaaacacct ggtctagcca
     3181 gatgttgaaa agagagtgaa acatttgatg atgtaaaggt taagtcgtac ctgtctagaa
     3241 taataatagt ttcctccatt tacatagagt tcagcaccgt gaaaaatgga aatggggtga
     3301 atataactat aagtctttcc agtcgtatta ccaagcaagg gggcaacagt ctcacgagag
     3361 tactgtttgg ctagagccaa ggtattttcc ttgccatttt gggcgataaa atcgatatag
     3421 gcaggtccaa aattataggc ttgaacagct gtccagatat ctacaccctt cttctgcgcc
     3481 agatagagat tgcctgtcag agtttgaatg ccttgccgaa tgctagaggc attatcattg
     3541 atggtattgg tggaaccact tgcagactca ctagactgca taacatcgcc ttcttttcct
     3601 tttgtttcag tataaatcat agcaagcaca agctcttcgt ttgctggggt gtctttttca
     3661 ctcaatattt ctcgcaccat gggttgatag gtcatgactt gtttgacatc ttgatgaacg
     3721 cggtaagctt tatatccagc aaaaaggaag actgctagta caagcactct tcgaattcgt
     3781 ttaaacatta tttactttgg atatcctcga tatttttgat taagatagag taggttccat
     3841 tttcgttttg gataaactca acagactcgg cgtcttgata gacgttattg ggaacgatga
     3901 gctcaattcc atttgataag gagagttttt ggttttcaaa tttctttaat tggcgactgg
     3961 catcaatttc atcaaattga acaggttctg gtacggcttc tttgacttgg tcaataaagc
     4021 tcaaacgagc cgtcagattg ttgtcaaaaa ggtcattagc caatttctca ggtgacaatt
     4081 cattgctttc ttctaggttg ttgaaaatag ctgatttgac cttggattga aattgaaaat
     4141 catctgtgtt aaaagattca gcaattctct gggctgtttt ttccagttcc ttgatagatt
     4201 ttttaggaga aatcttagga gcgacagcaa gaagattatc tgaaaaatag ttcaaaaaag
     4261 tcccgttgta cttgattcgt ttttcaatca ggtgatactt gctactctga agattgacca
     4321 ccaaggcctc atcagctcct gttccaaatc caggcaggtt attctgagtt agcttgattg
     4381 gattatcaac ttctcctccg aggtgggtca aggtctcccg cagggcaatt cgcaagaaag
     4441 cgaaatgttc tacaccttct ttagaaaatt gaacaaaaat caagtcattg gtcttgagat
     4501 tttcagaaat gctaaactcc tctttccaga gattagccag cgttactgat gtctccaaca
     4561 aatcgtctgt aatatgattg aagaagggat tttcttcttc gaaaatccca gtcttggctt
     4621 catctgaata cacatgttca atttttttac gtaggtattc ttcgattttt ggagtaatat
     4681 tgagaaactt atctgctaag aacagctcgg tatcatccgg actgaactgg tgaataatgg
     4741 ctttcttaat ataaatgtcc ataaaagttt tattcctcgt ataatgggaa ggcatctgtc
     4801 aattctttga ctgcacttct cacttcttct aatacagcct cattttctga attcttaagg
     4861 gttttaatga tgagttcagc cactttgcga ctttcttctt caccaaatcc acgtgcagta
     4921 atagctgctg ctccgatacg aatcccactt gtcttgaatg gtgacaagct ttcgtaaggg
     4981 attgagtttt tatttaaggt aatattgact tcatccaaca agttttgagc aactttgccg
     5041 ttttctacaa ctttagtcac atcaacaagg aagagatggt tttcagttcc acctgaaata
     5101 atacggaaat cagggtcttg caagaagaca tctgccatag ccttgctgtt cttaattaca
     5161 ttggcagcat attccttgaa ggctggatcc aaaacttctt tgaaggaaac tgccttagcc
     5221 gccacaacat gctctaaagg accgccctga atacctggga aaatagctga attgattttt
     5281 ttagcaagtt cttcgtcatt ggtcaaaatc aaaccaccac gaggtccacg aagggttttg
     5341 tgggtcgttg ttgttgtgat atgagcgtat ggaactgggc ttggatgaag gccagccgca
     5401 accaagccag cgatatgggc catgtccacc atgagcttcg caccgacagc atctgcgatt
     5461 tcacggaatt ttgaaaaatc gataatttga gaataggctg aagcaccagc tacaatcagt
     5521 tttggtttta cttcttgggc ttgtttcaag atagcatcaa agtctaagag ttccgtttta
     5581 ggatcaacac tataagaaac aaagttgtag gtttgaccag agaagctaac aggagcccca
     5641 tgagtcaaat gaccacctga tgccaaatcc attcccataa ccgtatcacc tggctcaatc
     5701 aaggacatgt aagccgcaca gttagcttgg cttcctgaat gtggttgaac attggcaaat
     5761 ttagcaccga aaatttcttt tgcgcgttca atagcaagag tctctacaac gtctactaca
     5821 tcagttccac cataataacg gcgtcctggg taaccctcgg catatttatt tgtcaagata
     5881 gacccttgag ctgccataac agccttggaa actacgtttt ccgaagcaat taactcgata
     5941 ttattttgtt ggcgttcttc ttctttggca atagcattcc agagatcagc atcatatgct
     6001 ttaaaatcat ctttgtcaaa aatcataggt cttctccttt attgtgtgac tagtccatta
     6061 gtttgatttt acaataagaa aatcaaacta acagatgcga ataaaccgtt tctgcatttt
     6121 atcacaagta tagccaactt tttcataaaa tgcatgagca cccagacgat gattggcaga
     6181 atttaagcgg ataaacccat aaccacatct ttttgcttct tcttccaacc cttgtagtaa
     6241 acttttacca ataccttgac cttgcgcttg aggtgaaact gctaaagcta agatattaaa
     6301 tcctgctttg gaatagagtg attcgtaaac ttcagcgtgg acatatccaa gtaagacatg
     6361 attagctgca tcctcatagc caagtaggaa atgatgggaa tcctgagaca gtctagctag
     6421 ttggctagcc gtttcctctg gactaaaagt ataacccaaa gcctcttggt tgatgtcaca
     6481 tatcgctttc acatctgttt cttgcaaatc tcttagcatt tcaagcctcc tcaaaagaaa
     6541 tctctgacaa ccgagcaaga atatcttctc gtttaattgc gccttggcgt aagattttca
     6601 ccttgtctcc agacaaatcc acaatagttg aatcctgtcc agttagaaaa gcatcgtctt
     6661 ccagacccag aacctcttgg tcaaaatcct tcagaatttg ttcaaaggtt acaccacttg
     6721 cctgacctga gatattggca gacggcccaa tcaagggacc tgtctctcga attaaatcca
     6781 gtgtgatagg gtgactgggc atccgaaatc caatagttgc aaggtcagaa tttacccaat
     6841 agggaactcg gtcattggct tcgagaataa tggtcaaggg acctggcaaa aaggtctcta
     6901 caagtttttg tagataagct ggctgattct ttgaaaagtg caagatgtcc tcgaaagagg
     6961 cgatattgag attgagtgcc ttatctctag gacgacgttt gagttggtaa acatggtcaa
     7021 ctgctttttc atctaaggcc ttggaaaaaa gaccataaac agtctctgta ggtagaacga
     7081 cagctccacc cttttccaac tcttgtctaa tcctgtccat catcaaccac aaccatccta
     7141 ttttgaccaa attggtcttt gagtgttcga actctttttt caggaagatg ttttctaaaa
     7201 agttcgggaa cactttgacc ttgcttgtat ccaatttcaa ggtaaatctt accaccatcc
     7261 ttgagatagt cttttgcatc ttccgcaatt ctacagtaaa tagctaggcc atcctcgtct
     7321 gcaaagagag ctagatgagg ctccgaatgc aaaacattca agcctacctc tgactcatct
     7381 tcacgagaga tatagggtgg attggataca attatatcat atttttcaga aatttctgca
     7441 aaacaatcag attttttaaa aaatatatta agattttgat cgctagcatt ctctgatgca
     7501 agctctaagg cctcttgaga aacatctgct gctgtcactg accaatctgg tctatttttt
     7561 gctagagcga gagcaatagc tccactacct gttccaatat ccagaactga gagattcgtc
     7621 tcaagatttt cagttagaat aagctccact aactcctctg tttctggacg aggaatcaaa
     7681 acccgttcat ccacctttaa atgcattcca taaaaatctg cctgtccaat gatgtactga
     7741 gctggcttgt gagctgctag ttgctggtaa atatcttcta caaattgttt ttcttcctct
     7801 gttgtcacct cctgctggag ggcaaaaata aagtctgtaa aagatagatt tttcagacta
     7861 cgatagacaa aagagaggct ttccgcttcc tctccttgtc ttatcaactc ttcttcaaaa
     7921 tttgaaaata attgagctaa tttcattatt tgtttaattc ttctagtttt tgtgtttggt
     7981 cataaagcac caaggcatcc acaacttcgt ccaatttacc agacaaaatc gtatctagtt
     8041 tttggagggt caagccgata cggtggtctg tgacacggtt ttgtgggaag ttataagttc
     8101 ggatccgttc tgaacggtca ccagtaccga ttgtcgactt acgctcagcg tcttgttcat
     8161 cctgagcaat ctgagcaaag tggtcagcga cgcgtgcacg gataatcttc atagccttct
     8221 cgcggttctt ctgctgggta cgttcttcct gcatctcaac cttgatattg gttggcaagt
     8281 gaacgatacg aacggcagtc gcaaccttat tgacgttctg tccaccagca ccagaggcgt
     8341 gatagatgtc gacacgaagg tcttttggat caatgtcgta ttcaacctct tcaacttctg
     8401 gcataacaag aactgtcgct gtcgaagtat gaacacggcc ttggctttct gtcacaggaa
     8461 cacgttgcac acggtgggca cctgattcat acttaagctt agagtataca gactgacctg
     8521 aaaccatagc aaccacttct ttaaaaccac cgacaccatt catagaggct tccatgactt
     8581 caaagcgcca accttgggct tccgcatact tttggtacat agttagcaaa tctccagcga
     8641 aaagtgccgc ttcgtctcca ccagctgctc cacggatttc aaggatgata ttcttgtcat
     8701 cgtttggatc ctttggaagg agcaaaattt tcagtttttc ttcatattct tctttttcag
     8761 ccttggcatc tttgagttct tgcttggcca attcttccaa gtccgcatct ccgcctgatt
     8821 ccttaatcat ctcttcggca tcgacgatat tttgaaggac ttgtttatac tcacggtagg
     8881 ctattacggt gtcacgattg gaagcttctt cttttgaaag ctccataaaa cgcttggtgt
     8941 ctgaaacgac atcagggtca ctcagcaatt ctcctagttc ttcataacgg tcttctacag
     9001 cttgtagttg atcatagatg ttcatttttc ttcattctcc ttattgattt caggggcaaa
     9061 ataatgttta cggcaaaccg agatataggt ttcattacca ccaatctgga tctgttctcc
     9121 atcgtaaacg ggcagtccat cctgtgttcg caacaccatg gtcgcctttt tcttgcaata
     9181 ctgacagatg gtcttgattt cgtcaatctt gtccgctaaa agcaagagat atttggaacc
     9241 ttcgaacaat tcattgcgaa agtcattttt caagccaaaa gccatgacgg gtatgtctaa
     9301 ctcgtccaca acacgagcta ggtcataaac atggtggcgt ttgagaaact gggcttcatc
     9361 gaccaaaaca cagtaaggtt tttctggtag gtctcggata tagccaaaga tatccgttgt
     9421 ttcctcaatc gcaagggcag ggcgtttcat gccaattcga ctcgacacat agccaacacc
     9481 gtcacgcgta tccagagccg aggtcataat gacaacacct tttccttgct cctcgtagtt
     9541 ataggccact ttgagaatct caatcgtttt accagagttc atggtcccat aacgatagta
     9601 caactgtgcc atgtttcttg cttcacgtcc atttctaaat ttttgctaca ttctagtata
     9661 tcataatttt cttaagcttt aaacggcaaa atgtggtaaa atagaagaaa tcaaaaacta
     9721 gtggaggaag ctattatgcc atttgtacgc atcgatttat ttgaaggacg cacgctcgag
     9781 caaaagaaag ctcttgctaa ggaagtaacg gaagcggttg ttcgcaacac tggagcacct
     9841 caatctgctg tccatgtcat catcaacgac atgccagaag gaacttactt cccacaaggg
     9901 gaaatgcgta ccaaataagc tagcttaagc agaattgctt aggctttttc aatctccaag
     9961 tagcattcat tgaagaaata tcctaaattt gttacaattt gaaaagaaac ttggagaatt
    10021 tccaagaaaa gagcaattaa ttaaaggaaa cattatgatt acacgtgaat ttgataccat
    10081 cgctgctata tctactccac taggtgaagg ggctattggt attgtccgcc tgagcggaac
    10141 agacagtttt gctattgcgc aaaagatttt taaaggaaaa gacttgaaca aggttgccag
    10201 ccacactctc aactacggtc acattatcga tcctctgact ggtaaagtca tggacgaggt
    10261 tatggttggg gctatgaagt ctccaaagac cttcactcgt gaggatatta tcgagattaa
    10321 cacccacggt gggattgcgg tgaccaatga gattctccag ctagctatcc gtgagggagc
    10381 tcggttggca gaacctggtg aatttaccaa acgtgccttt ttaaacggtc gcgtagattt
    10441 gacacaggcc gaggcggtga tggatatcat ccgcgccaag acagacaagg ccatgaacat
    10501 tgcagttaag caattagacg gctccctttc tgacctcatt aacaataccc gtcaagaaat
    10561 cctcaataca cttgcccaag ttgaggtcaa tatcgattat cctgaatatg atgatgttga
    10621 ggaagctact actgccgttg tccgtgagaa gactatggag tttgagcaat tgctaaccaa
    10681 gctccttagg acagcccgtc gtggtaaaat ccttcgtgaa ggaatttcaa cggctatcat
    10741 tggacgtccc aacgttggga aatcaagcct tctcaacaac ctcttgcgtg aggacaaggc
    10801 tatcgtaaca gatatcgctg ggacaacacg agatgtcatc gaagagtacg tcaacatcaa
    10861 tggtgtacct ctcaaattga ttgatacagc cggtattcgt gaaacagatg acatagtgga
    10921 acaaatcggt gttgagcgtt cgaaaaaagc cctcaaggaa gccgacttgg ttctactagt
    10981 gctaaatgcc agtgaaccac tgactgcgca agacagacaa cttcttgaaa ttagccaaga
    11041 taccaatcgc attattctac ttaataaaac cgacctgcca gaaacgattg aaacttcgaa
    11101 actacctgaa gacgttatcc gtatttcagt ccttaaaaac caaaacatcg acaagattga
    11161 agagcgaatc aacaacctct tctttgaaaa tgctggcttg gtcgagcaag atgctactta
    11221 cttgtcaaac gcccgtcaca tttccctgat tgaaaaagca gttgaaagcc tacaagccgt
    11281 taatcaaggt cttgagctgg ggatgccagt tgatttgctt caagttgact tgactcgtac
    11341 ttgggaaatc ctcggagaaa tcactgggga tgctgctcca gatgaactca tcacccaact
    11401 ctttagccaa ttctgtttag gaaaataaga aaaatccatg atccttcatt cggtcatgga
    11461 ttttattgtc tttattagta atctggtctt aagacccctg ttacagttgc cttagttgct
    11521 tcgtagtcgc catctacgac aaccttgata atgcgtttgg catcttcttc tggtgctgga
    11581 acaagaggta gacgagtggg tccagcttca aatcccatat agttaagaac tgccttaact
    11641 ggagcaggac ttggataaga gaagagagca ttaaccttag gaatgaattt acgctgaatt
    11701 gctgcggctt tcttcatatc gctttctgca atggcagtaa acatctcgtg catttcatcc
    11761 ccatttgtat gagaggcaac agaaataacc ccatccgccc caaggttcat ggcatggaaa
    11821 gcatctccat cctcacctgt ataaatcaag aactcttcag gcttgtgctc aatcaagtaa
    11881 gccatattag ccaagctagt acattctttg acaccgataa tatttggatg gtcagccaaa
    11941 cgaagcatgg tttctggagt caattcgaca actacacgcc ctggaatgtt atagataata
    12001 attggtaggt cagaagcatc tgcaatagcc ttaaagtgct gatacatccc ttcttgagaa
    12061 ggtttgttgt agtaaggaac aatagcaagc ccagctgcga aaccaccaaa ttccgctact
    12121 tctttgacaa actcaataga gtcacgcgta tcattagtac ctacacccgc aatcaaagga
    12181 acgcgtccat tgacaacctt ttgtacagcc gcaaacaact ccaactcctc atcgtgggtc
    12241 aaagttggac tctcagcagt cgttcctgcg agaagaattc catccgtatg atgggccaat
    12301 aaatgctcaa tcaaggctgg aatagcatca aagttaatgg aaccatcctc atggaagggg
    12361 gtaataaagg ctgtaatgat tttacattct tttaaatctt gataagacac gaaaacacct
    12421 ctctatttca aagaaggagt tcatctgaac tcctaaacga tatgactatt ttaattcaaa
    12481 tttcaattcg gctgttggac gaaccaatcc acgttcatga agagtttcag caatctgaac
    12541 tgagttccaa gcagcacctt tgagaaggtt atctgaaaca acccacatgt gaattccttt
    12601 ttctgcatcc atgtctttac ggatacgacc aacaaaggta tcacgcgaac caactgcatt
    12661 gatagcttga ggatagattt gatgagctac atcatcttca agaacagcac ctgggaaggc
    12721 tgcgatagct gcttttactt cttcgattgg agccacttct tttgtttcga tataaacaga
    12781 ctcagagtga gctgacaaga ctggaatacg cacacatgtt gcagatactg caatgctatc
    12841 atcttccata attttcttag tttccttggt catcttcatc tcttcgtacg tgtaatcatt
    12901 atcagtgaaa acatcaattt gtggaagagc gttaaaggcg ataggataat gtttcttgtc
    12961 accacctgaa ggcaagattt ccgcatgcaa atcacgtggt ttcacaccat cattcaagac
    13021 ttcacgaagt tcacgttgtg tctcaagaat tgctcccata ccagcacctg aaacggcttg
    13081 ataagttgaa acaatgatac ggtccaagcc ccatttttgg cgaaccggct caagagccac
    13141 catcatttgg attgttgaac aattagggca ggcaatgatt ccgttgtgag catcaagtgc
    13201 atgagcattg acctctggaa caaccaaagg aacatctgga ttttgacgga aataagatgt
    13261 attatctact actaccacgc cagcttttac tgcgtatggt gcatacttag ctgatgtaga
    13321 actacctgct gaaaagagag caatatcaac tccttcaaaa gctgtttcag tcgtttcttc
    13381 aattgtaata tcttgatctt taaatttcaa tgacttacct gctgaacgtg cagaagcaag
    13441 gtaacggatt ttatcgattg gaagtgttga ttcttccaac atttttatca tctgagcacc
    13501 gacagcacct gtcgcgccga ctacagcaac tgtatatccc ataaataacc tctttcggaa
    13561 ttttctaaaa atttctataa tagaagtatt atactacttt ttccatgaat tgcaaagctt
    13621 tttcattatt ttttggaaaa taaaaatccc agtcgctaga ctagggacta agaggcatct
    13681 tcatgtgatg agcaggttca cacaactcat caaggtccgc tcctgcgtta tgacctcctt
    13741 atgctcaata gtagtccgaa gactacctat cgactcatcg catattctat attactagag
    13801 atacttgatt ttgtcaataa gaaatttttt cgatcgagta taacaaaaaa ctcttgtatt
    13861 caagagtttc cctatacata tcatgctaat tgccgggatt gaaccggcga cctcatcctt
    13921 accatggatg cgctctgcca actgagctaa atcagcttac ttaagaagta tactataatc
    13981 agaaaaactt gtcaagtttc cttagaaatt ttccatagga aaaagccagg taagaactac
    14041 ctagcttatc ttcttctatt tacttaaatc aattcgacga ccaattttac caataataat
    14101 cgctccaata atcaatgaag caaattcacc gattcctgtt gtaaaccaag taaggaagaa
    14161 tggtaattct gctacaatat ttaactctgc agcgatagta aacatggaaa ttgaaaagag
    14221 gattgaaaag aagaaatgat cttttcgaat caatccgtta aagaggtaat ccttgctata
    14281 ttttgcaaaa agccaaacac ctaaactgag gaatactaag gttgaaccac caccaacaaa
    14341 gacatctagc agtccgaagc taaagaaatt agcaatcata caaccgatgg taactccgat
    14401 gatgtactta ggattgtaaa aagccataaa gttcatcatt tctgaaatac gaaactgata
    14461 agcaccatag ctgatggcat ttaggggcgg tgtgacagtc aaaacgacgt agatagcagc
    14521 gacgattgca atatctgcaa catcacgaat agttaatttt ttcatctttt ctcctttggc
    14581 ggttatccgc gtgtaatatg cttggtgaaa gaagctaagc accaagggtt gattcattca
    14641 accttactag tatagcacaa tagcctgctt tatgctatac ttaaagcatg aaaaaaccta
    14701 ttcaaaaatt ttttaacaat gaaatcttag cctatctctt ttttggcctt gcgacaactc
    14761 tagtttcgat tctctcacga ctagtcattt atcaactaag tcatcaggaa ctccttgcta
    14821 cggccttggc aaatattatc ggtatcttat ttgcctttat cacaaatgat acgattgtat
    14881 ttaagcaaaa aaagaaaaat agacttatcc gtttagtgaa attttctctt gctcgccttt
    14941 ctacttttct gttagacttg tttttaactt ttctctttgt aacccaattt cctcacatca
    15001 tagggcaatt cgtaactgaa aacattgata agataaatgc tattgaaaca ataattgcac
    15061 aaatattcat tattatcatc aattatatct tgagcaaggt ctatattttt agaaaataat
    15121 gctccattta tgagcctttt aattgccttc tataatgatt taggatacaa tgaaacacga
    15181 aacattgaaa ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt cgaggaaatg
    15241 ttattgacct tgctgtcggt gttgtcattg cctctgcttt tggtgctatc gttacttcac
    15301 ttgtaaacga cattatcact cctcttattt taaatcccgc tttgaaagct gctaaagtcg
    15361 aacgtatcgc tcaactttct tggcatggag tcggctatgg taacttttta agtgctatta
    15421 tcaattttat ctttgtaggt accgccctct tctttattat caagggcatt gaaaaagcac
    15481 agaaactgac tggcataaag aaagaaaaaa ctgccgaaaa aaaaccaacc gaattggaag
    15541 tccttcaaga aataaaagct ctccttgaga aaaaataatc gattaaaagg atctagcgca
    15601 aagctaaatc cttttttctt tactctttgg gtaacttgcc tgctttttca agcatttttt
    15661 tgataagata aggcatctta atattctccc gccctttttt ctcaatcagt tttttcacaa
    15721 attctggcat ttgtaaatct tcagattcag ctaaaatgtt tttcgtctcg tctgaaggaa
    15781 ctaactcatc aaaggtctct tcttctggga gaaattcctt aaactcttga ttttcattga
    15841 ctctaactgt attgaccaaa gcatcaatca aacgagaatc tgtatttggc attggtggac
    15901 gatggtagtt taccccaaat tcctgacata aatcataaca ttccacatca ttgtcaaaca
    15961 agacctcaat atgctcactg atgaaactaa taggtacaaa aatataatgg tctggatgtt
    16021 ctgtctgttc tctgagatac tccaaaacat ctggtttaat ccatggaata ccaatatcac
    16081 tctcactctg ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt tcagcgacta
    16141 gcttgctatt ttcgaaaatt tggtctatat aaggatctcc aaagtccaag gcaaaaatag
    16201 gcacactatg ggctgaaaag atgactttaa agctgtcttg ctttacttct tcttttaaaa
    16261 tcttagcaat ttcatctgcc caatagttta agagcgcttc ttcctgatac cagtccttaa
    16321 tgaccaaaaa ttgaatttgt ttgctttcta aaaatttttc atagcccatg acagagtaga
    16381 aagaataatg gggctccaaa atcaagcaaa tacactgttc aattccgtct gcttccattt
    16441 gaccgatcac atctggaata aagggactgg aaaacttatt agcaaagtag acactgtatt
    16501 cattccccag cctagcttct accaaggcaa cctcttgacg ggtaattttt tgcagaggcg
    16561 tgcctccaat tcgtacataa ttatcataga gagtctgaat ctcgtggtct tggggtctca
    16621 tcccacgacg aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc tcttctggtg
    16681 aaccgaaggt catcattaaa attgcttttt tcatgactgc ttccttgtga tgtttttatc
    16741 aagtttattt tatcattaat tcatcgataa gtaaacgcta gcatagggac attctcaatc
    16801 ttctgtcttt tgtttttctc ttctttctat gatacaatgg aaaaaataaa ttcaaaagga
    16861 gttttttatg acttatccaa atctcttgga ccgcttctta acctacgtta aggtcaacac
    16921 gcgctctgat gaacactcta ctactactcc aagtacacag agtcaggttg acttcgcaac
    16981 aaatgtccta attcctgaaa tgaaacgtgt tggactgcaa aatgtttact atctaccgaa
    17041 tggttttgct attggaacct tgccagccaa cgatccgtct ttaacacgta agattggttt
    17101 tatatcgcac atggatactg ctgattttaa tgctgaagga gtcaatccac aggtaattga
    17161 aaactacgat ggtggtgtga ttgaactagg gaattctggt ttcaaactcg atccagctga
    17221 cttcaagagt cttgaaaaat atccaggaca aacgctcatc acaacagatg gaacaagctt
    17281 gctaggcgct gatgacaaat caggaattgc tgaaattatg acagccattg aatatctaac
    17341 tgctcatcct gaaattaagc actgtgagat tcgtgttggt tttggtccag atgaagaaat
    17401 cggtgttggt gccaataaat ttgatgcaga agattttgat gtggattttg cctacactgt
    17461 tgatggtggt ccactaggtg aacttcagta cgagactttc tcagccgctg gtgctgaatt
    17521 gcatttccaa ggccgtaatg tccaccctgg tactgccaaa gggcagatgg tcaatgccct
    17581 tcagctagca attgattttc ataatcaact tccagaaaat gaccgacctg agttaactga
    17641 aggttaccaa ggtttttacc atctaatgga tgtgacaggt agtgttgagg aggcgcgtgc
    17701 aagctacatc attcgtgatt ttgaaaaaga tgcctttgaa gcgcgtaaag catccatgca
    17761 atctatcgct gataagatga atgaagaact tgggagcgac cgtgtcactc tcaacttgac
    17821 agaccagtac tacaatatga aagaagtcat tgaaaaagat atgactccaa ttaccattgc
    17881 taaagccgtt atggaagatc taggtatcac gcctattatc gaaccaatcc ggggtggaac
    17941 agacggctct aagatttcct ttatgggaat cccaactccg aatatctttg caggtggcga
    18001 aaatatgcac ggacgttttg aatacgttag ccttcagact atggaacgtg cagttgatac
    18061 catcattggc atcgtagctt ataaaggcta aaaagacgag gtagctcagc tacttcgcct
    18121 ttctttttat tctactggtt tttcttgatt tccagtagtt gtagaagatt ctgttgtttt
    18181 attttctgaa gttgattcag caggtttaga atctcttgta ttgcttggtt tgttttcgtc
    18241 gctagcagtt tcaatgttag attctgcagt tgcgtttggt tggttctcag cactggtgtt
    18301 atcaccattt gcttcagcat ttcttgctgg acttgtttct tcacttgcgc tagcttttga
    18361 ctggatttga tgattcaaaa ctagaatagc ttttgtcgat tcaagtaaag ctgttttgtc
    18421 tttactatta gcagaaagtt gatctaataa tgcatccacc ttatcaaaag tccgcatcag
    18481 atccattatt actttctaaa taaaagtgaa gcgacatgag aatatcgtag agtttttgat
    18541 agagtacaag tgtctgagga tcttgctcag cattttcctt ttcttgttga agggcgctag
    18601 cgatacgagt caagacatct tttacctgac tgtttacttc atccaagtct gcatcagcct
    18661 tgtttgtggc agcttttaga ttttctactt cttctgccaa agattgtctg attccttctt
    18721 catggattcg ttccaagagt tgatttgcct tgctcaaaag actttctact tcttccttgc
    18781 tatctgtcgc agattattgg ttgctatcta ccatgtactc ctaaaacagg agagttataa
    18841 tccaagatta caaggcctta cagaaataag aaatccagat aagacaatgt tcgtccaaga
    18901 cgctattcgc ttcgcacagc agcacggatt caatatgctt taattttaaa gtttaggtgt
    18961 caagacctct ttttagtgtg cccaaaattt agagaagtaa tcaatcaact aacttttatt
    19021 tttttcaaac tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg ttcgataggc
    19081 ttgtctttgt agatgcttct gctatcagct agaagttgat ctacttttgc caagactgcc
    19141 ttctcatcaa aagttccagg ttgatagttg gattgcaggg atggaatctt gtttttcaaa
    19201 gccgcttcat atcccttagt ttgaaccttg atgtagtgat tgtggtcgcc acgaggaatc
    19261 acaaaacctt ctgaatcttc acttataatt cgattggcat caaaaccatg accatcttct
    19321 tcctcatggt ggacatgtag tgacggatta cttaatacag aactagaaga acttcctacc
    19381 tcttccgtgt tagagtgtga tgggggattg ttaagagatg acttaggaat atagtgatag
    19441 tgaccccatg tcttactata taagcatcac ctgtatctct gacaatatca ttagggttaa
    19501 agacataacc atcatctgct gcagaaacac cattattcgg tgtcaccgac aaagattgac
    19561 tgagagctgt agtattctct gataattata cttttgcagc tgctaattca cctgccgaca
    19621 agtcactctc aggaatgaaa tgatagtgac caccatgtgg tactatagta gattgaaata
    19681 gaatatgagc aaattgataa ggggatttta aagtaatttc taacaatgat ttagaaacta
    19741 tgatgtgcta ttctaaattc aactcactat atataaccat catcggtagt ataacgtccc
    19801 tgtaatttta ctacagatac ttctgcacta gctcctttat cgtctttacc atgttcttgt
    19861 ttttggcgat tgatttcatc ttttattcgt acattttctg catgagcttg atctttaagg
    19921 taaacataat actttccatc taccttaata atatatcctc ccttaaccta actgacgata
    19981 tcttgatctt tcggctgata gttgggggct ttcattaata gctcttcact aaagagcgca
    20041 tccaaaggaa ctttaccatt atagcagtga taatgatcgc catgagaagt tacataacct
    20101 tgatctgtaa tcttaataac aatttgtttt gcttgaattc cttctttttg actaacctag
    20161 tctggagtca aattttcagt cttcttagtg tctttattac tgtttacata tgaaacacga
    20221 tttttatctg tattggcctg ttagctatgt tggttcagag cataaacaca cagacttaag
    20281 gaaaggataa caacagatcc agctgctata tatttctttt taaatttcat aa
//
LOCUS       DAVLZG010000033        20310 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLZG010000033 DAVLZG010000000
VERSION     DAVLZG010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.033"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            14..556
                     /locus_tag="VYO72_001214"
     CDS             14..556
                     /locus_tag="VYO72_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1707590.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(597..670)
                     /locus_tag="VYO72_001215"
     tRNA            complement(597..670)
                     /locus_tag="VYO72_001215"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(634..636),aa:Asn,seq:gtt)
     gene            complement(676..747)
                     /locus_tag="VYO72_001216"
     tRNA            complement(676..747)
                     /locus_tag="VYO72_001216"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(712..714),aa:Glu,seq:ttc)
     gene            complement(799..1551)
                     /locus_tag="VYO72_001217"
     CDS             complement(799..1551)
                     /locus_tag="VYO72_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707591.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(1548..2873)
                     /locus_tag="VYO72_001218"
     CDS             complement(1548..2873)
                     /locus_tag="VYO72_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1707592.1"
                     /translation="MDLFGFGTVIVHFLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(2894..3019)
                     /gene="comC"
                     /locus_tag="VYO72_001219"
     CDS             complement(2894..3019)
                     /gene="comC"
                     /locus_tag="VYO72_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1707593.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(3185..3258)
                     /locus_tag="VYO72_001220"
     tRNA            complement(3185..3258)
                     /locus_tag="VYO72_001220"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3222..3224),aa:Arg,seq:tct)
     gene            complement(3302..3781)
                     /gene="rlmH"
                     /locus_tag="VYO72_001221"
     CDS             complement(3302..3781)
                     /gene="rlmH"
                     /locus_tag="VYO72_001221"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1707594.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEELSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3964..5145
                     /locus_tag="VYO72_001222"
     CDS             3964..5145
                     /locus_tag="VYO72_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEV1707595.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            5203..5961
                     /locus_tag="VYO72_001223"
     CDS             5203..5961
                     /locus_tag="VYO72_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1707596.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            6174..7535
                     /gene="dnaA"
                     /locus_tag="VYO72_001224"
     CDS             6174..7535
                     /gene="dnaA"
                     /locus_tag="VYO72_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1707597.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            7694..8830
                     /gene="dnaN"
                     /locus_tag="VYO72_001225"
     CDS             7694..8830
                     /gene="dnaN"
                     /locus_tag="VYO72_001225"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1707598.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8895..9089
                     /locus_tag="VYO72_001226"
     CDS             8895..9089
                     /locus_tag="VYO72_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1707599.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            9173..10288
                     /gene="ychF"
                     /locus_tag="VYO72_001227"
     CDS             9173..10288
                     /gene="ychF"
                     /locus_tag="VYO72_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1707600.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            10359..10928
                     /locus_tag="VYO72_001228"
     CDS             10359..10928
                     /locus_tag="VYO72_001228"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1707601.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10929..14438
                     /gene="mfd"
                     /locus_tag="VYO72_001229"
     CDS             10929..14438
                     /gene="mfd"
                     /locus_tag="VYO72_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1707602.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            14506..14772
                     /locus_tag="VYO72_001230"
     CDS             14506..14772
                     /locus_tag="VYO72_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1707603.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            14765..15133
                     /locus_tag="VYO72_001231"
     CDS             14765..15133
                     /locus_tag="VYO72_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1707604.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            15253..16521
                     /locus_tag="VYO72_001232"
     CDS             15253..16521
                     /locus_tag="VYO72_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1707605.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            16518..17795
                     /gene="tilS"
                     /locus_tag="VYO72_001233"
     CDS             16518..17795
                     /gene="tilS"
                     /locus_tag="VYO72_001233"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1707606.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            17799..18341
                     /gene="hpt"
                     /locus_tag="VYO72_001234"
     CDS             17799..18341
                     /gene="hpt"
                     /locus_tag="VYO72_001234"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1707607.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEVDYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            18357..>20310
                     /gene="ftsH"
                     /locus_tag="VYO72_001235"
     CDS             18357..>20310
                     /gene="ftsH"
                     /locus_tag="VYO72_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1707608.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNKARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         7022 a         3287 c         3778 g         6223 t
ORIGIN      
        1 acaaggagga aatatgcaag aaagtaacaa acgcttaaaa acaaagcgaa ctattgaaaa
       61 tgctatggta caattactga tggaacagcc atttgataaa atttctactg tcaaattagt
      121 agaaaaagcc ggaattagtc gttccagctt ctatactcac tataaggata agtatgatat
      181 gattgagcac tatcaaagca agctattcca tacatttgaa tatatttttc aaaaacatgc
      241 tcatcacaaa agagacgcta ttttagaagt ttttgaatat ctagagtcag aaccacttct
      301 ggctgccctt ctttctgaaa atgggactaa agaaatccaa aatttcttac gaaataaact
      361 tcatatcatg cttagtacag atttacaaaa gcgatttatg caactgaatc taaataccac
      421 tgaattagaa tatagtagca tctatctaac tcatgcactt tttggtgtct gccaaacttg
      481 gattgcacat ggaaaaaaag aaagttctca agaaataaca gacttcctta tgaaaatgct
      541 tggtgataca aattgataca aaaagaggaa cacagctgtg ttccctttta tctatactcc
      601 gccagtagga ctcgaaccta cgacatcatg attaacagtc atgcgctact accaactgag
      661 ctatggcgga taaaatagtc cgtacgggat tcgaacccgt gttaccgccg tgaaaaggcg
      721 gtgtcttaac cccttgacca acggaccttc tatctgtagc agatataacc attatatcaa
      781 tttcttgcta attgtcaatc acttttgaga ttttttctct aaaatatctt ttaattttct
      841 aatttttaat cttgaaatag gacaacgatg gtcttcatag aaaacaattt ctaagttttt
      901 tcgatcaatt tctctgatat tgcctatatt taccaaaaat gacttgtgag gagaataaaa
      961 tcgctgagta tgtttgtcct tttcctgaat atctgtcatg gtaccataaa actcttttgc
     1021 aaaattctta ccaataatgc gcaatttatg agatacccct gttgtttcaa tatacaaaat
     1081 atcatggtaa ggaattttta aatcatttcc cttgtaattg tagtcgaaat aatctacaac
     1141 atcttcattt tcaagtaaca tactcttcgt gtagaagata ttttgctcaa ttctcttctt
     1201 aaacatctca tcattgatat ccttatcaac aaaatctagg gctgatacct ggtatttata
     1261 ggttagagtc gcaaactctg atcgactagt gataaagacg ataatagcgt aaggattgta
     1321 atgacgaatg agctgagcca cttcaaatcc ctttttctca attccatgaa tatcgatatc
     1381 taggaaataa agctgattta cttcatcatt ttcaatgtat tcttcaaatt cacggacttt
     1441 tcccgttgtc ttgtatgata ttggaatatt cgattctttc gaaatttcat ccaatattct
     1501 ctctagtctc acttgatgtt caataacatc ttctaaaatt aaaactttca ttcaaattcc
     1561 ctcttaaatc taatgatttg tctaaatgta ctgccttcca tctctgtttc taaaataata
     1621 ttgttgtact tatctagtag ttctttcaca ttatttaatc cgactccgcg atttcttccc
     1681 ttagtggaga atcctaagga aaatagatct cctgaaggag tcatcgtcat tttacatgaa
     1741 ttctgaatca caataactgt ttcagtttcc atcttaataa ctgctacttc catctgcttt
     1801 ttatagctat cagccgatcc ttcgacagca ttattcaata aaacgctcat gatacgaacc
     1861 aaatccaata gttcaattgg aagcttggta atcgtatctt ttacttccag tgtaaactct
     1921 acaccattat ttcgagcata gacaattgac tgagcaacca aacttcgtaa agctgagtct
     1981 tctatgttgt tcaaatcaaa gtaagtgtac ttatctgaac gcaatttatg atttgctttg
     2041 actaaaactt cattgtaaat tctgtcaatt tcctgtaaat taccactgtc aattgccatc
     2101 tgcatgctga caagcattcc agcataatca tgtcgaaaac cacggatttc attatacaga
     2161 ccaacaattt catctgtgta attctgtaaa tgtttctgtt caaatttctt ctgcttcaaa
     2221 gcaatctctt tctccatttg aactttatga gaattcattg caaagaaggt caaaaggaga
     2281 gagataaaga caatagatga caaaatactt ccaaaactat tcaaatgttt aatcgtactt
     2341 accatatctg aaacgaaaga tacaatatgt agcaatagta aagcaaaaaa tacttttttc
     2401 aagaaaggat aaaggtagtc cttgtcaaaa taggctagtt ccaaatggaa atagtaaatg
     2461 atttttaatg taacaaaata ggttaacacc gtcacaacga aaaagaatgg gaaatgatat
     2521 tgtaaaacaa aattatctcc tgttatagag gagaaagtta cggacagaaa gttatgagtg
     2581 ctctcatata aaagagatag tagtaaactt aggaatagtc ctctatccct ctcatactgt
     2641 tttatccatc gaaaatagga atataggccc aaaggaaata aaaatgttgc aatccctaac
     2701 ccatctaaat atagaatata taagggaaaa tcaaatacta tttctgttag taatgtataa
     2761 gcaccaaaaa cgaataattc ttttctattt atttgacctt tacaaattaa atggtagttg
     2821 tgactaataa ttaaaaaatg aacaataact gtcccaaatc caaataaatc cattactctt
     2881 tccccttatt tcattacttt tttctttgta aaataaaatc acggaagaat tttgacagcc
     2941 tcatctcccc acctttaatc ttttgtaagt ctttttcctt caaagctaca aactgttcca
     3001 atttaactgt gtttttcata ataaaatctc ctaaaatgtt tttttcttgt aagctaactt
     3061 acaaaaacca ttatacaaaa tggaatttcg ttttagataa aattctctca actgtcattt
     3121 ttttctccca aagtgtactt ttttaagaaa aaagccggga aaattcccag ctttgctatt
     3181 atattgatcc cagcaggatt cgaacctgcg accgttcgct tagaaggcga atgctctatc
     3241 cagctgagct atgagaccta acacaattat tctaccaaaa attcaattaa aagtcaattt
     3301 tctatttatg gtaggggaat ccctgctgaa tcgtaaaagc gcgatagatt tgttcaacaa
     3361 gaactagtct cattaactga tgaggcaagg ttaggcgacc aaaactgaca gaaagattgg
     3421 ctctattttt tacagatgat gacaatccta aacttccccc aataataaaa gtaagagtag
     3481 aaaatccttt tatagaagtt tcttctaact gcttactcaa ttcttctgag aagaaagttt
     3541 tcccttcaat ggctaacaca ataacgaaat cacggtcagc aatttttgat aaaattctct
     3601 gaccttctat ttctaaaatc ttttgatttt ctgattcact ggccttatct ggtgtttttt
     3661 catctgataa ctcaatcatt tcaaacttag caaatctaga aattcgtttt gaatactctg
     3721 cgataccatc ttttaaatac ttttctttca gtttcccaac tgttacaact ttaattttca
     3781 tgactctatt ctaacatatt ctctattttt tcacatctta ttcacaaaat aaaaaataga
     3841 tttcaattaa gaaaatcaca gtttcaaaag agttatccac agtttgtgta aaacttttgt
     3901 gtttaagtta taattaagct agtcagttta tactttcagt aattcaaaca tatggaggca
     3961 aatatgaaac atctaaaaac attttacaaa aaatggtttc aattattagt cgttatcgtc
     4021 attagctttt ttagtggagc cttgggtagt ttttcaataa ctcaactaac tcaaaaaagt
     4081 agtgtaaaca actctaacaa caatagtact attacacaaa ctgcctataa gaacgaaaat
     4141 tcaacaacac aggctgttaa caaagtaaaa gatgctgttg tttctgttat tacttattcg
     4201 gcaaacagac aaaatagcgt atttggcaat gatgatactg acacagattc tcagcgaatc
     4261 tctagtgaag gatctggagt tatttataaa aagaatgata aagaagctta catcgtcacc
     4321 aacaatcacg ttataaatgg cgccagcaaa gtagatattc gattgtcaga tgggactaaa
     4381 gtacctggag aaattgtcgg agctgacact ttctctgata ttgctgtcgt caaaatctct
     4441 tcagaaaaag tgacaacagt agctgagttt ggtgattcta gtaagttaac tgtaggagaa
     4501 actgctattg ccatcggtag cccgttaggt tctgaatatg caaatactgt cactcaaggt
     4561 atcgtatcca gtctcaatag aaatgtatcc ttaaaatcgg aagatggaca agctatttct
     4621 acaaaagcca tccaaactga tactgctatt aacccaggta actctggcgg cccactgatc
     4681 aatattcaag ggcaggttat cggaattacc tcaagtaaaa ttgctacaaa tggaggaaca
     4741 tctgtagaag gtcttggttt cgcaattcct gcaaatgatg ctatcaatat tattgaacag
     4801 ttagaaaaaa acggaaaagt gacgcgtcca gctttgggaa tccagatggt taatttatct
     4861 aatgtgagta caagcgacat cagaagactc aatattccaa gtaatgttac atctggtgta
     4921 attgttcgtt cggtacaaag taatatgcct gccaatggtc accttgaaaa atacgatgta
     4981 attacaaaag tagatgacaa agagattgct tcatcaacag acttacaaag tgctctttac
     5041 aaccattcta tcggagacac cattaagata acctactatc gtaacgggaa agaagaaact
     5101 acctctatca aacttaacaa gagttcaggt gatttagaat cttaattgac atctatgtaa
     5161 agaaagcttt acataagaga aaagatgtgt tagtgtagaa tcatggaaaa atttgaaatg
     5221 atttctatca cagatataca aaaaaatccc tatcaacccc gaaaagaatt tgatagagaa
     5281 aaactagatg aactagcaca gtctatcaaa gaaaatgggg tcattcaacc gattattgtt
     5341 cgtcaatctc ctgttattgg ttatgaaatc cttgcaggag agagacgcta tcgggcttca
     5401 cttttagctg gtctacggtc tatcccagct gttgttaaac agatttcaga ccaagagatg
     5461 atggtccagt ccattattga aaatttacag agagaaaatt taaacccaat agaagaagca
     5521 cgcgcctatg aatctctcgt agagaaagga ttcacccatg ctgaaattgc agataagatg
     5581 ggcaagtctc gtccatatat cagcaactcc attcgtttac tttccttgcc agaacagatt
     5641 ctctcagaag tagaaaatgg caaactatca caagcccatg cgcgttccct agttgggtta
     5701 aataaggaac aacaagacta tttctttcaa cggattatag aagaagatat ttctgtaagg
     5761 aagttagaag ctcttctgac agagaaaaaa caaaagaaac agcaaaaaac taattatttc
     5821 atacaaaatg aagaaaaaca gttaagaaaa ctactcggat tagatgtaga aattaaacta
     5881 tctaaaaaag acagtggaaa aatcattatt tctttttcaa atcaagaaga atatagtaga
     5941 attatcaaca gcctgaaata aggctgttct tttatttttt tatctcacaa ggttatccac
     6001 tatgtttttc gataaaaagc ttaataaatc aataatttct tcttttatcc ccaacctgtg
     6061 gataaagttt agtaacattg tggattattt ttcacagctt gtggaaaatt cttgctatct
     6121 atggtaaaat atctctagta ttaaactttt aaatagtaaa ggaggagaaa ggattgaaag
     6181 aaaaacaatt ttggaatcgt atattagaat ttgcacaaga aagactgact cgatccatgt
     6241 atgatttcta tgctattcaa gctgaactca tcaaggtaga ggaaaatgtt gccactatat
     6301 ttctacctcg ctctgaaatg gaaatggtct gggaaaaaca actaaaagat attattgtag
     6361 tagctggttt tgaaatttat gacgctgaaa taactcccca ctatattttc accaaacctc
     6421 aagatacgac tagctcacaa gttgaagaag ctacaaattt aactctttat gactatagtc
     6481 caaagttagt atctattcct tattcagata cgggattaaa agaaaagtat acctttgata
     6541 actttattca aggggatgga aatgtttggg ctgtatcagc cgctttagct gtctctgaag
     6601 atttggctct gacctataac cctcttttta tctatggagg accaggcctt ggtaagactc
     6661 acttattaaa cgctattgga aatgaaattc taaaaaatat tcctaatgcg cgtgttaaat
     6721 atatccctgc cgaaagcttt attaatgact ttcttgatca cctaagactt ggggaaatgg
     6781 aaaagtttaa aaagacctat cgtagtcttg atcttttgtt aatcgatgat atccagtcac
     6841 tcagcggaaa aaaagtcgca actcaggaag aatttttcaa tacctttaac gcccttcatg
     6901 acaagcaaaa acagattgtc ctaacgagtg atcgtagtcc aaaacatcta gaagggctcg
     6961 aggagaggct tgtcacgcgt tttagttggg gattgacaca aactatcaca ccccctgact
     7021 ttgaaacacg tattgccatt ttacaaagta aaacggaaca tttaggctac aatttccaaa
     7081 gtgatactct agaataccta gctgggcaat ttgattcaaa tgttcgagat cttgagggag
     7141 ccatcaacga catcacttta attgccagag taaaaaaaat caaggatatc actattgata
     7201 ttgctgcaga agccattaga gcccgcaaac aagatgttag ccaaatgctc gtcatcccaa
     7261 ttgataaaat ccaaactgaa gttggtaact tttatggtgt tagtatcaaa gaaatgaagg
     7321 gaagtagacg ccttcaaaat attgttttgg cccgtcaagt agccatgtat ttatctagag
     7381 aactaacaga taatagtctt ccaaaaattg ggaaggaatt tgggggaaaa gatcatacca
     7441 cagtcattca tgcccatgcc aaaataaaat ctttgattga tcaagacgat aatttacgtt
     7501 tagaaattga atcaatcaaa aagaaaatca aataatttgt ggataacttt tagtttttta
     7561 tcttttttat ccacattttt taaacaagct aaaaaacttg atatgacttg tttaaaggct
     7621 gttttccaca gatttcacag actctattat tactattatc tttctaatac taaaaataaa
     7681 taaaggagaa tccatgattc atttttcaat taataaaaat ttatttctac aagcattaaa
     7741 tactactaag agagctatta gttctaaaaa tgccattcct attttatcaa cagtaaaaat
     7801 tgacgtgacc aatgaaggta ttactttaat tggttcaaat ggtcaaattt caattgaaaa
     7861 ttttatttct caaaaaaatg aagatgctgg tttgttaatt acttctttag gttcgatcct
     7921 tcttgaagct tctttcttta tcaatgtagt atctagttta cctgatgtaa ctcttgattt
     7981 taaagaaatt gaacaaaatc aaattgtttt aaccagtggc aaatcagaaa ttaccctaaa
     8041 aggaaaagat agcgaacaat atccacgaat ccaagaaatt tcagcaagca ctcctttaat
     8101 acttgaaaca aaattactca agaaaattat taatgaaaca gcctttgctg caagtacaca
     8161 agagagtcgt ccgattttaa caggtgtcca cttcgtattg agtcaacaca aagagttaaa
     8221 aacagttgca acagactctc atcgcctaag ccagaaaaaa ttgactcttg aaaaaaatag
     8281 tgatgatttt gatgtcgtaa ttcctagccg ttctctacgc gaattttcag cggtatttac
     8341 agatgatatc gaaactgtag agattttctt tgccaataat caaatcctct ttagaagcga
     8401 aaatattagc ttctatactc gtctcctaga aggaaactat cctgatacag atcgcttgat
     8461 tccaacagac tttaacacta ctattacttt taatgtggta aacttacgcc agtcaatgga
     8521 gcgtgcccgt cttttatcaa gtgcgactca aaatggtact gtgaaacttg aaattaagga
     8581 tggggttgtt agcgcccatg ttcactctcc agaagttggt aaagtaaacg aagaaatcga
     8641 tactgatcag gttactggtg aagatttgac cattagtttc aacccaactt acttgattga
     8701 ttctcttaaa gctttaaata gcgaaaaggt gactattagc tttatctcag ctgttcgtcc
     8761 atttactctt gtgccagcag atactgacga agacttcatg cagctcatta caccagttcg
     8821 tacaaattaa gtgaaagagg ttgagcctgg ctcgcctctt ttatgatata atcgaaaaag
     8881 aaaaggagag tagtatgtat caagttggaa attttgttga gatgaaaaaa tcacacgctt
     8941 gtacaatcaa gtcgactggt aaaaaggcta atcgttggga aattacacgt gtaggagcag
     9001 atatcaaaat aaaatgcagt aattgtgagc atgttgtcat gatggggcga tatgattttg
     9061 agcgaaaaat gaataaaatt attgactgag aacccttagt tagagggtta gcactttatc
     9121 cctttttgtg ttataatatt agggattgaa atgaaaacgg agaatgagaa atatggcttt
     9181 gacagcaggt atcgttggtt tgccaaacgt tggtaaatca acactattta atgcaattac
     9241 aaaagcagga gcagaggcag caaactaccc atttgcgact attgatccaa atgttggaat
     9301 ggtggaagtt ccagatgaac gcctacaaaa actaactgaa atgataactc ctaaaaagac
     9361 agttcccaca acatttgaat ttacggatat tgcagggatt gtaaaaggag cttcaaaagg
     9421 agaagggcta gggaataaat tcttggccaa tattcgtgaa gtagatgcga ttgttcacgt
     9481 agttcgtgct tttgatgatg aaaatgtgat gcgcgagcaa ggacgtgaag acgcctttgt
     9541 ggatccactt gcagatattg acaccattaa cctagaattg attcttgcag acttagaatc
     9601 agtcaataaa cgatatgcgc gtgtagaaaa gatggcacgt acgcaaaaag ataaagaatc
     9661 agtagcagaa ttcaatgttc ttcaaaagat taaaccagtc ctagaagacg ggaaatcagc
     9721 tcgtaccatt gaatttacag atgaggaaca aaaggttgtc aaaggtcttt tccttttgac
     9781 gactaaacca gttctttatg tagctaatgt ggacgaggat gtggtttcag aacctgactc
     9841 tatcgactat gtcaaacaaa ttcgtgaatt tgcagcgaca gaaaatgctg aagtagtcgt
     9901 tatttctgcg cgtgctgagg aagaaatttc tgaattggat gatgaagata aaaaagagtt
     9961 tcttgaagcc attggtttga tagaatcagg tgtagataag ttgacgcgtg cagcttacca
    10021 cttgcttgga ttgggaactt acttcacagc tggtgaaaaa gaagttcgcg cttggacttt
    10081 caaacgtggt atgaaggctc ctcaagcagc tggtattatc cactcagact ttgaaaaagg
    10141 ctttattcgt gcagtaacca tgtcatatga ggatctagtg aaatacgaat ctgaaaaggc
    10201 cgtaaaagaa gctggacgct tgcgtgaaga aggaaaagaa tatatcgttc aagatggcga
    10261 tatcatggaa ttccgcttta atgtctaaaa attaataaat ggtgtcaatt aggttggaaa
    10321 aaaattccaa cccttttggc ttttgaaagg aaaaataaat gaccaaatta cttgtaggct
    10381 tgggaaatcc aggggataaa tattttgaaa caaaacacaa tgttggtttt atgttgattg
    10441 atcaactagc gaagaaacag aatgtcactt ttacacacga taagatattt aaagctgacc
    10501 tagcatcctt tttcctaaat ggagaaaaaa tttatctggt taaaccaacg acctttatga
    10561 atgaaagtgg aaaagcagtt catgctttat taacttacta tggtttggat attgacgatt
    10621 tacttatcat ttacgatgat cttgacatgg aagttgggaa aattcgttta agagcaaaag
    10681 gctcagcagg tggtcataat ggtatcaagt ctattattca acatatagga actcaggtct
    10741 ttaaccgtgt taagattgga attggaagac ctaaaaatgg tatgtcagtt gttcatcatg
    10801 ttttgagtaa gtttgacagg gatgattata tcggtatttt acagtctgtt gacaaagttg
    10861 acgattctgt aaactactat ttacaagaga aaaattttga gaaaacaatg cagaggtata
    10921 acggataaat ggtgacctta ttagatttat tctcagaaaa tgatcagatt aaaaaatggc
    10981 atcaaaattt aactgataag aaaagacaac taatacttgg tttatcaaca tctactaagg
    11041 ctcttgcaat tgcaagcagt ttagaaaaag aagataggat tgtgttattg acgtcaactt
    11101 atggagaagc agaaggactt gttagtgatc ttatatctat cttgggtgag gaactcgtct
    11161 atccattttt ggtagatgat gctcctatgg tggagttttt gatgtcttca caggaaaaaa
    11221 ttatttcacg ggttgaagcc ttgcgttttt tgactgattc atctaagaaa gggattttag
    11281 tttgtaatat cgcagcaagt cgattgattt taccgtctcc caatgcattc aaagatagta
    11341 ttgtaaaaat ctcagttggt gaagaatatg atcaacacgc gtttatccat cagttaaagg
    11401 aaaatggcta tcgaaaagtt actcaagtac aaactcaggg cgaatttagt cttcgaggag
    11461 atattttaga tatttttgaa atatcccagt tagaaccttg tcgaattgag ttttttggtg
    11521 atgaaattga tggtatcagg tcatttgaag tagaaacaca attatcgaaa gaaaataaga
    11581 cagaactcac tatctttcca gctagtgata tgcttttgag agaaaaggat tatcaacgag
    11641 gacagtcagc tttagaaaaa caaatttcaa aaactttatc acctattttg aaatcatacc
    11701 tagaagaaat tctttcaagt tttcaccaaa aacaaagtca tgcagactct cggaagtttt
    11761 tatctttgtg ctatgataag acatggactg tctttgatta tattgaaaaa gatactccaa
    11821 tattctttga tgattatcaa aaattgatga atcagtatga agtctttgaa agagacttag
    11881 cgcagtactt tacagaagaa ttacagaata gtaaagcatt ttctgatatg cagtattttt
    11941 ctgatattga acaaatctat aaaaaacaaa gtccagtgac ctttttctct aatcttcaaa
    12001 agggtttagg aaatctcaaa tttgacaaaa tttatcaatt caatcaatat cctatgcagg
    12061 aatttttcaa tcagttttct tttctaaaag aagaaattga acgatataaa aaaatggatt
    12121 acaccattat tctgcagtct agcaattcaa tgggaagtaa aacattggag gatatgttag
    12181 aggaatatca gattaaattg gattctagag ataagacaaa tatctgtaaa gaatctgtaa
    12241 acttaataga gggtaatctc agacatggtt ttcattttgt agatgaaaag attttattga
    12301 taactgaaca tgagattttt caaaagaaat taaagcgtcg ttttcgaaga caacatgttt
    12361 caaatgcaga gagattaaaa gattacaatg aacttgaaaa aggggactat gttgtccatc
    12421 atatccatgg gattggtcaa tatctaggaa ttgaaaccat tgaaatcaag ggaattcatc
    12481 gcgattatgt cagtgtccaa taccaaaatg gtgatcaaat ttctatcccc gtggaacaga
    12541 ttcatctact gtccaaatat atttcaagtg atggtaaagc tccaaaactc aataaattaa
    12601 atgacggtca ttttaaaaag gccaagcaaa aggttaagaa ccaggtagag gatatagctg
    12661 atgatttaat caaactctac tctgaacgta gtcagttgaa gggttttgct ttctcagctg
    12721 atgatgatga tcaagatgcc tttgatgatg ctttccctta tgttgaaacg gatgatcaac
    12781 ttcgtagtat tgaggaaatc aaaagggata tgcaggcttc tcagccaatg gatcgacttt
    12841 tagttgggga tgttggtttt ggaaagactg aagttgctat gcgtgcagcc tttaaagcag
    12901 tcaatgatca caaacaggtt gtcattctag ttccgacgac ggttttagcg caacagcact
    12961 atacgaattt taaggaacga ttccaaaatt ttgcagttaa tgttgatgtg ttgagtcgct
    13021 ttagaagtaa aaaagagcag actgcaacac ttgaaaaatt gaaaaacggt caagtcgata
    13081 ttttgattgg aacacatcgt gttttgtcaa aagatgttgt gtttgctgat ttgggcttga
    13141 tgattattga tgaggaacag cgatttggtg tcaagcataa ggaaactttg aaagaactga
    13201 agaaacaagt ggatgtccta accttgaccg ctacgccaat ccctcgtacc ctccatatgt
    13261 ctatgctggg aatcagagat ttgtctgtta ttgaaactcc gccgactaat cgctatcctg
    13321 ttcagaccta tgttttggaa aagaatgata gtgtcattcg tgatgctgtc ttgcgtgaaa
    13381 tggagcgtgg aggtcaagtt tactatcttt acaacaaagt tgacacaatt gttcagaagg
    13441 tttcagaatt acaggagttg attccggagg cttcgattgg atatgttcat ggtcgaatga
    13501 gtgaagtcca gttggaaaat actctattag actttattga gggacaatac gatatcttgg
    13561 tgacgactac tattattgag acaggggtgg acattccaaa tgctaatact ttatttattg
    13621 aaaatgcgga ccatatgggc ttgtcaacct tatatcagtt aagaggaaga gtcggtcgta
    13681 gtaatcgtat tgcttatgct tatctcatgt atcgtccaga aaaatcaatc agtgaagtct
    13741 ctgaaaagag attagaagcg attaaaggat ttacagaatt gggctctggc tttaagattg
    13801 caatgcgaga tctttcgatt cgtggagcag gaaatctttt aggaaaatcc cagtctggtt
    13861 tcattgattc tgttggtttt gaattgtatt cgcagttatt agaggaagct attgctaaac
    13921 gaaacggtaa tgctaacgct aacacaagaa ccaaagggaa tgctgagttg attttgcaaa
    13981 ttgatgccta tcttcctgat acttatattt ctgatcaacg acataagatt gaaatttaca
    14041 agaaaattcg tcaaattgac aaccgtgtca attatgaaga gttacaagag gagttgatag
    14101 accgttttgg agaataccca gatgtagtag cctatctttt agagattggt ttggtcaaat
    14161 catacttgga caaggtcttt gttcaacgtg tggaaagaaa agataataaa attacaattc
    14221 aatttgaaaa agtcactcaa cgactgtttt tagctcaaga ttattttaaa gctttatccg
    14281 taacgaactt aaaagcaggc atcgctgaga ataagggatt aatggagctt gtatttgatg
    14341 tccaaaataa gaaagattat gaaattttag aaggtctgct gatttttgga gaaagtttat
    14401 tagagataaa agagtttaag gaagaaaatt ccatttgata tttttcttct ataaaataga
    14461 taaaaataga taaaaatggt acaataataa attgaggtaa taaggatgag attagataaa
    14521 tatttaaaag tatcgcgaat tatcaagcgt cgtacagtcg caaaggaagt agcagataaa
    14581 ggtagaatca aggttaatgg aatcttggcc aaaagttcaa cggacttgaa agttaatgac
    14641 caagttgaaa ttcgctttgg caataagttg ctgcttgtaa aagtactaga gatgaaagat
    14701 agtacaaaaa aagaagatgc agcaggaatg tatgaaatta tcagtgaaac acgggtagaa
    14761 gaaaatgtct aaaaatattg tacaattgaa taattctttt attcaaaatg aataccaacg
    14821 tcgtcgctac ctgatgaaag aacgacaaaa acggaatcgt tttatggggg gggtattgat
    14881 tttgattatg ctattattta tcttgccaac ttttaatttg gcgcagagtt atcagcaatt
    14941 actccaaaga cgtcagcaat tagcagactt gcaaactcag tatcaaactt tgagtgatga
    15001 aaaggataag gaaacagcat ttgctaccaa gttgaaagat gaagattatg ctgctaaata
    15061 tacacgagcg aagtactatt attctaagtc gagggaaaaa gtttatacga ttcctgactt
    15121 gcttcaaagg tgataaaatg gaaaatttat tagacgtaat agagcaattt ttgagtttgt
    15181 cagatgaaaa gctggaagaa ttgactgata aaaatcaatt attgcgttta caagaagaaa
    15241 aggaaaggaa gaatgcgtaa attcttaatt attttgttgc taccaagttt tttgaccatt
    15301 tcaaaagtcg ttagcacaga aaaagaagtc gtctatactt cgaaagaaat ttattacctt
    15361 tcacaatctg actttggtat ttattttaga gaaaaattaa gttctcccat ggtttatgga
    15421 gaggttcctg tttatgcgaa tgaagattta gtagtggaat ctgggaaatt gactcccaaa
    15481 acaagttttc aaataaccga gtggcgctta aataaacaag gaattccagt atttaagcta
    15541 tcaaatcatc aatttatagc tgcggacaaa cgatttttat atgatcaatc agaggtaact
    15601 ccaacaataa aaaaagcatg gttagaatct gactttaaac tgtacaatag tccttatgat
    15661 ttaaaagaag tgaaatcatc cttatcagct tattcgcaag tatcaatcga caagaccatg
    15721 tttgtagaag gaagagaatt tctacatatt gatcaggctg gatgggtagc taaagaatca
    15781 acttctgaag aagataatcg gatgagtaaa gttcaagaaa tgttatctga aaaatatcag
    15841 aaagattctt tctctattta tgttaagcaa ctgactactg gaaaagaagc tggtatcaat
    15901 caagatgaaa agatgtatgc agccagcgtt ttgaaactct cctatctcta ttatacgcaa
    15961 gaaaaaataa atgagggtct ttatcagtta gatacgactg taaaatacgt atctgcagtc
    16021 aatgattttc caggttctta taaaccagag ggaagtggta gtcttcctaa aaaagaagat
    16081 aataaagaat attctttaaa ggatttaatt acgaaagtat caaaagaatc tgataatgta
    16141 gctcataatc tattgggata ttacatttca aaccaatctg atgccacatt caaatccaag
    16201 atgtctgcca ttatgggaga tgattgggat ccaaaagaaa aattgatttc ttctaagatg
    16261 gccgggaagt ttatggaagc tatttataat caaaatggat ttgtgctaga gtctttgact
    16321 aaaacagatt ttgatagtca gcgaattgcc aaaggtgttt ctgttaaagt agctcataaa
    16381 attggagatg cggatgaatt taagcatgat acgggtgttg tctatgcaga ttctccattt
    16441 attctttcta ttttcactaa gaattctgat tatgatacga tttctaagat agccaaggat
    16501 gtttatgagg ttctaaaatg agggaaccag attttttaaa tcattttctc aagaagggat
    16561 atttcaaaaa gcatgctaag gcggttctag ctctttctgg tggattagat tctatgtttc
    16621 tatttaaggt attgtctact tatcaaaaag agttagagat tgaattgatt ctggctcatg
    16681 tgaatcataa gcagagaatt gaatcagatt gggaagaaaa ggaattaagg aagttggctg
    16741 ctgaagcaga gcttcctatt tatatcagca atttttcagg agaattttca gaagcgcgtg
    16801 cacgaaattt tcgttatgat ttttttcaag aggtcatgaa aaagacaggt gcgacagctt
    16861 tagtcactgc ccaccatgct gatgatcagg tggaaacgat tttgatgcgc ttgattcgag
    16921 gaactcgctt gcgctatcta tcaggaatta aggagaagca agtagtcgga gagatagaaa
    16981 tcattcgtcc cttcttgcat tttcagaaaa aagactttcc atcaattttt cactttgaag
    17041 atacatcaaa tcaggagaat cattattttc gaaatcgtat tcgaaattct tacttaccaa
    17101 aattggaaaa agaaaatcct cgatttaggg atgcaatctt aggcattggc aatgaaattt
    17161 tagattatga tttggcaata gctgaattat ctaacaatat taatgtggaa gatttacagc
    17221 agttattttc ttactctgag tctacacaaa gagttttact tcaaacttat ctgaatcgtt
    17281 ttccagattt gaatcttaca aaaactcagt ttgctgaagt tcagcagatt ttaaaatcta
    17341 aaagccagta tcgtcatccg attaaaaatg gctatgaatt gataaaagag taccaacagt
    17401 ttcagatttg taaaatcagt ccgcaggctg atgaaaagga agatgaactt gtgttacact
    17461 atcaaaatca ggtagcttat caaggatatt tattttcctt tggacttcca ttagaaggtg
    17521 aattaattca acaaatacct gtttcacgtg aaacatccat acacattcgt catcgaaaaa
    17581 caggagatgt tttgattcaa aatgggcata gaaaaaaact cagacgttta tttattgatt
    17641 tgaaaatccc tatggaaaag agaaactctg ctcttattat tgagcaattt ggtgaaattg
    17701 tctcaatttt gggaattgcg accaataatt tgagtaaaaa aacgaaaaat gatataatga
    17761 acactgtact ttatatagaa aaaatagata ggtaaaaaat gttagaaaac gatattaaaa
    17821 aagtcctcgt ttcacacgat gaaattacag aagcagctaa aaaactaggt gctcaattaa
    17881 ctaaagacta tgcaggaaaa aatccaatct tagttgggat tttaaaagga tctattcctt
    17941 ttatggctga attggtcaaa catattgata cacatattga aatggacttc atgatggttt
    18001 ctagctacca tggtggaaca gcaagtagtg gtgttatcaa tattaaacaa gatgtgactc
    18061 aagatatcaa aggaagacat gttctatttg tagaagatat cattgataca ggtcaaactt
    18121 tgaagaattt gcgagatatg tttaaagaaa gagaagcagc ttctgttaaa attgcaacct
    18181 tgttggataa accagaagga cgtgttgtag aaattgaggt agactatacc tgctttacta
    18241 tcccaaatga gtttgtagta ggttatggtt tagactacaa agaaaattat cgtaatcttc
    18301 cttatattgg agtattgaaa gaggaagtgt attcaaatta gaaagaataa tctttaatga
    18361 aaaaacaaaa taatggttta attaaaaatc cttttctatg gttattattt atctttttcc
    18421 ttgtgacagg attccagtat ttctattctg ggaataactc aggaggaagt cagcaaatca
    18481 actatactga gttggtacaa gaaattaccg atggtaatgt aaaagaatta acttaccaac
    18541 caaatggtag tgttatcgaa gtttctggtg tctataaaaa tcctaaaaca agtaaagaag
    18601 gaacaggtat tcagtttttc acgccatctg ttactaaggt agagaaattt accagcacta
    18661 ttcttcctgc agatactacc gtatcagaat tgcaaaaact tgctactgac cataaagcag
    18721 aagtaactgt taagcatgaa agttcaagtg gtatatggat taatctactc gtatccattg
    18781 tgccatttgg aattctattc ttcttcctat tctctatgat gggaaatatg ggaggaggca
    18841 atggccgtaa tccaatgagt tttggacgta gtaaggctaa agcagcaaat aaagaagata
    18901 ttaaagtaag attttcagat gttgctggag ctgaggaaga aaaacaagaa ctagttgaag
    18961 ttgttgagtt cttaaaagat ccaaaacgat tcacaaaact tggagcccgt attccagcag
    19021 gtgttctttt ggagggacct ccggggacag gtaagacttt gcttgctaag gcagtcgctg
    19081 gagaagcagg tgttccattc tttagtatct caggttctga ctttgtagaa atgtttgtcg
    19141 gagttggagc tagtcgtgtt cgctctcttt ttgaggatgc caaaaaagca gcaccagcta
    19201 tcatctttat cgatgaaatt gatgctgttg gacgtcaacg tggagttggt ctcggcggag
    19261 gtaatgacga acgtgaacaa accttgaacc aacttttgat tgagatggat ggttttgagg
    19321 gaaatgaagg gattatcgtc atcgctgcga caaaccgttc agatgtactt gatcctgccc
    19381 ttttgcgtcc aggacgtttt gatagaaaag tattggttgg ccgtcctgat gttaaaggtc
    19441 gtgaagcaat cttgaaagtt cacgctaaga acaagccttt agcagaagat gttgatttga
    19501 aattagtggc tcaacaaact ccaggctttg ttggtgctga tttagagaat gtcttgaatg
    19561 aagcagcttt agttgctgct cgtcgcaata aatcgataat tgatgcttca gatattgatg
    19621 aagcagaaga tagagttatt gctggacctt ctaagaaaga taagacagtt tcacaaaaag
    19681 aacgagaatt ggttgcttac catgaggcag gacataccat tgttggtcta gtcttgtcga
    19741 atgctcgcgt tgtccataag gttacaattg taccacgcgg ccgtgcaggc ggatacatga
    19801 ttgcacttcc taaagaggat caaatgcttc tatctaaaga agatatgaaa gagcaattgg
    19861 ctggcttaat gggtggacgt gtagctgaag aaattatctt taatgtccaa actacaggag
    19921 cttcaaacga ctttgaacaa gcgacacaaa tggcacgtgc aatggttaca gagtacggta
    19981 tgagtgaaaa acttggccca gtacaatatg aaggaaacca tgctatgttt ggtgcacaga
    20041 atcctcaaaa atcaatttca gaacaaacag cttatgaaat tgatgaagag gttcgttcat
    20101 tattaaataa ggcacgaaat aaagctgctg aaattattca gtcaaatcgt gaaactcaca
    20161 agttaattgc agaagcatta ttgaaatacg aaacattgga tagtacacaa attaaagctc
    20221 tttacgaaac aggaaagatg cctgaagcag tagaagagga atctcatgca ctatcctatg
    20281 atgaagtaaa gtcaaaaatg aatgacgaaa
//
LOCUS       DAVLZG010000034        20206 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLZG010000034 DAVLZG010000000
VERSION     DAVLZG010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.034"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..424
                     /locus_tag="VYO72_001236"
     CDS             <1..424
                     /locus_tag="VYO72_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1707609.1"
                     /translation="NQEQLFDQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLG
                     KDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQ
                     TNILAQLMNFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
     gene            462..764
                     /locus_tag="VYO72_001237"
     CDS             462..764
                     /locus_tag="VYO72_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1707610.1"
                     /translation="MIKILAACGAGVNSSHQIKSTLEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSAPVFDNIRLPAKQNMV"
     gene            772..1575
                     /locus_tag="VYO72_001238"
                     /pseudo
     CDS             772..1575
                     /locus_tag="VYO72_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1624..2088
                     /locus_tag="VYO72_001239"
     CDS             1624..2088
                     /locus_tag="VYO72_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1707611.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2245..2670
                     /gene="lacA"
                     /locus_tag="VYO72_001240"
     CDS             2245..2670
                     /gene="lacA"
                     /locus_tag="VYO72_001240"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1707612.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2701..3216
                     /gene="lacB"
                     /locus_tag="VYO72_001241"
     CDS             2701..3216
                     /gene="lacB"
                     /locus_tag="VYO72_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1707613.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3227..4156
                     /locus_tag="VYO72_001242"
     CDS             3227..4156
                     /locus_tag="VYO72_001242"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1707614.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            4158..5138
                     /gene="lacD"
                     /locus_tag="VYO72_001243"
     CDS             4158..5138
                     /gene="lacD"
                     /locus_tag="VYO72_001243"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1707615.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            5544..6020
                     /locus_tag="VYO72_001244"
     CDS             5544..6020
                     /locus_tag="VYO72_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707616.1"
                     /translation="MNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEE
                     LAKNIGISVQEASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAG
                     WHLKQFAVNPVTSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            6418..7254
                     /locus_tag="VYO72_001245"
     CDS             6418..7254
                     /locus_tag="VYO72_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1707617.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            7290..7607
                     /locus_tag="VYO72_001246"
     CDS             7290..7607
                     /locus_tag="VYO72_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1707618.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            7607..9298
                     /locus_tag="VYO72_001247"
     CDS             7607..9298
                     /locus_tag="VYO72_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1707619.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            9507..10913
                     /gene="lacG"
                     /locus_tag="VYO72_001248"
     CDS             9507..10913
                     /gene="lacG"
                     /locus_tag="VYO72_001248"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1707620.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            10956..11213
                     /locus_tag="VYO72_001249"
     CDS             10956..11213
                     /locus_tag="VYO72_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1707621.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEGWDTISFDSDFMPFQQS"
     gene            complement(11492..12253)
                     /locus_tag="VYO72_001250"
     CDS             complement(11492..12253)
                     /locus_tag="VYO72_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1707622.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(12435..13397)
                     /gene="nrdF"
                     /locus_tag="VYO72_001251"
     CDS             complement(12435..13397)
                     /gene="nrdF"
                     /locus_tag="VYO72_001251"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1707623.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(13585..15744)
                     /gene="nrdE"
                     /locus_tag="VYO72_001252"
     CDS             complement(13585..15744)
                     /gene="nrdE"
                     /locus_tag="VYO72_001252"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1707624.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(15825..16043)
                     /gene="nrdH"
                     /locus_tag="VYO72_001253"
     CDS             complement(15825..16043)
                     /gene="nrdH"
                     /locus_tag="VYO72_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1707625.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            16394..16657
                     /locus_tag="VYO72_001254"
     CDS             16394..16657
                     /locus_tag="VYO72_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1707626.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            16663..18396
                     /gene="ptsP"
                     /locus_tag="VYO72_001255"
     CDS             16663..18396
                     /gene="ptsP"
                     /locus_tag="VYO72_001255"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1707627.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            18650..>20206
                     /locus_tag="VYO72_001256"
     CDS             18650..>20206
                     /locus_tag="VYO72_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1707628.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEEPSPQPAPNPQPAPSNPIDEKLVKE
                     AVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSD
                     REFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVPSDKVKLVDDILAFLAP
                     IRHPERLGKPN"
BASE COUNT         6365 a         3640 c         4173 g         6028 t
ORIGIN      
        1 taatcaagaa caactctttg atcaggtagc aagcttgttg gaagaacgag aaattgtcac
       61 tcctacttat cgtgaagcct tgatcacgcg tgaaaagtca tttccaactg gtttagatat
      121 ggaatttcta ggaaaggact tgccaaatgt agcgattcct cacacagata ttgttcataa
      181 tctagctgag aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc acaatatgat
      241 agctcccgat aaggaagtag aagtatccct actcttcttt atcattaata attcaagttc
      301 aagtcaaacg aacattcttg ctcagttgat gaacttcttc acaggaaatg gacatcttga
      361 agacctatca aaaatttccg aaccagaaaa actttatgct tatatagatg aagcaatcgc
      421 ttaatcttgt ctattaaaaa ataaaatcgg aggaagtcta tatgattaaa attcttgctg
      481 cctgcggtgc aggtgttaac tcaagtcacc aaattaaaag tactctagaa gaagaacttt
      541 caaaccgtgg ttacgatgtt cactgtgatg cagtcatggt gaaagatgta aacgaagacc
      601 ttatgaaagg ttacgatatc tttacaccaa tcgctgcaac agatcttggt tttgaaccag
      661 gtatcccagt tatcgaagct gggccaatct tattttgtat cccagcaatg agcgctccag
      721 tatttgacaa tattagactc cctgcgaaac aaaatatggt atagtagttc tatgaatgat
      781 gaagcaagta aacaactaac cgatgcacga tttaagcgtc ttgttggtgt tcagcgtacc
      841 acttttgaag agatgttagc tgtattaaaa acagcttatc aacttaaaca cgcaaaaggt
      901 ggacgaaaac ctaaattaag cctagaagac cttcttatgg ccactcttca atatgtgcga
      961 gaatatcgca cttatgaaca attgcggctg attttggtat ccacgaaagc aacttactcc
     1021 gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg ttttacgatt tcaagaactc
     1081 ctctcagttc tgaggacacg gtaatgattg atgcgacgaa agtaaaaatc aatcgcccta
     1141 aaaaaagaat tagcgaatga ttctggtaaa aagaaatgcc acgctatgaa gtctcaggcg
     1201 attgtcacaa gtcaagggag aattgtttct ttggatatca ctgtgaacta ttgtcatgat
     1261 atgaagttgt tcaaaatgag tcgcagaaat atcggacaag ctggaaaaat cttggctgac
     1321 agtggttatc aagggcccat gaagatatat cctcaagcac aaactccacg taaatccagc
     1381 aaacttaagc cgctaatagc tgaagataaa gcctataact atgcgctatc taaggagaga
     1441 agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatgttttc aacaacctat
     1501 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggtat tatcaatcat
     1561 gaactaggat tctagttttt caggaagtct aataaagaaa ctagcaaggt caggccttac
     1621 tttattggtg gacatccagg atttaattgt cctctacttg atgatgaagt ctatgaagat
     1681 tattatctag agtttgagaa agaagagact tgctctgttc cacgtccttt cccagaaaca
     1741 ggtatgttgg atttccaaga tagaagtcca tggctagagg gacaaaaaga aatagatctt
     1801 agttatgatc ttttcagcac agatgcagtg actttggatg aattgcaatc tcgaacaatt
     1861 gcccttcgtt ctcttaaaca tgataaggga ttgaaagtgc attttgcaga atttccaaac
     1921 ctcatcatct ggtcaacttt gaacaaggga cctttcatta cctttgaacc atggtctggc
     1981 ttgtcaacat cccttgaaga aggagatcat ttagaagata agaagaatgt ttgtctctta
     2041 gaagccaatc aggttgaaga attagggttt gagatagaag ttttataaaa aagtaaaaaa
     2101 taaataacaa aaacaaacac aaactattga cttcttcaaa caatagtagt atattatgtt
     2161 tgtgaggact aattgactgt tttttaaaga tagccaatac actgctggaa tccagcatag
     2221 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
     2281 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
     2341 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
     2401 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
     2461 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
     2521 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     2581 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggtcg tcaccaaatc
     2641 cgggttgaca tgttgaacaa aatgggctaa ttagattata gtaagaaagg taagttaaaa
     2701 atgagaattg caattggatg tgaccacatc gtaactgatg aaaaaatggc ggtttcagaa
     2761 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     2821 cactacccaa tctttggtaa aaaagtaggg gaagcagtaa ctagtggtca agctgatctc
     2881 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     2941 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     3001 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     3061 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     3121 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     3181 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     3241 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     3301 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     3361 actttcagaa tttggcgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     3421 gtttttggtt gaacatatcg ataatcaagt aaagaaagat ttcttctcaa ttcagggaga
     3481 aactcgtaac tgtatcgcta ttctccacgg agacaaccaa acagaagttc ttgaaaaagg
     3541 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     3601 gtcagttgaa gtagtggcca tctcaggtag tctgccagct ggccttccag ttgattacta
     3661 tgcgagcttg gtagaacttg ctaatcaagc tggcaagcct gtagtcttgg actgctcagg
     3721 tgcagcactt caggctgttc ttgaatcacc ccataaacca acagtcatca aaccaaataa
     3781 tgaagaattg tctcagcttc ttggaagaga agtttctgag gatttggatg aattaaaaga
     3841 agtacttcaa gaacctttgt ttgcagggat tgaatggatt atcgtttcac ttggtgccaa
     3901 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     3961 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     4021 caaagaatcg gatgcagaat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     4081 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     4141 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     4201 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     4261 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaagtct
     4321 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     4381 ttccagcaac taaagctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     4441 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     4501 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     4561 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     4621 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggatgcag
     4681 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggcgctatg aaagtctttt
     4741 cagacccacg ctttaacatt gatgttttga aagttgaagt tcctgttaac attaaatatg
     4801 ttgaaggctt cgctgaaggt gaagtagttt atacacgtga agaagcagca gccttcttca
     4861 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     4921 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     4981 tttgtggccg tgctacatgg gcaggatcag ttgaagctta catcaaagat ggtgaagcag
     5041 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgacgaactc aacaaagttc
     5101 ttcaaagaac agcaacttca tggaaagaac gcgtgtaaga aagtcctcct agtttaggaa
     5161 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     5221 tgctatactt aaatcacaag ttaatatgaa ttagaaagta actatatgaa gtataataaa
     5281 aataggatat agtttatttt acgagctagg aaggaaaaat acggaaacaa tattgccaga
     5341 ataaactata tttagatgca catttcattc attgttttat aaaaggagaa gataaacggc
     5401 tactaaaaag agttttaaag cgttagttgt aggactaggt attgtttcaa tattctcatc
     5461 agccttacct atggttagtg gttctgtatt tgcagatagt gccctaacta cagtatacag
     5521 tagataaagc aaatgatatt gttttgaatg ttgatgggaa taaattttat aatgtttcgg
     5581 tttcagaaga tattgtaaat gctggtcaaa ttttggaaga ttatttttat gtagataaat
     5641 ttggaaatat aaatttaaaa ggcactcctg aagagttagc aaaaaatatt ggtatttctg
     5701 tacaagaagc aagtttgatg tatgaagctg taaaagagtt acccaacgtt tacgaaagag
     5761 gtcctgtagg ttttcgtttc aatcttggtc ctcaagtgag ggggatgggt ggctgggctg
     5821 ctggagcttt cgctactgga tatgctggat ggcatttgaa acaatttgcg gttaatcctg
     5881 ttacatctgg atttgttgct gtaataagtg gtgcgattgg ctgggctgta aaaactgctg
     5941 tagaaaatta ttggacagtt gctgtagcta cagtagaagt gccgtttgtg aaccttgttt
     6001 acaccataga tttaccttag aggttatttc tttatgaatc attcttttaa aaaaataact
     6061 gtattttgtt ttatagtttc ttgtgttctt tgtttattag acttaatgaa ttttaaaaat
     6121 gtagctactt ttttattttt ctgtcttcct gtttttgttt tgatttacaa aaataaataa
     6181 aaacagagcc tctgtttgat gaattttaga acatagttaa gttttaaaaa aagttgtatg
     6241 taaaggttta caaaacaacc gacttgtgct atacttaaat cacaagttaa tacaaggtga
     6301 gtgttactaa gtaatattag gcatgatcac aggtgaatta gaaatcagct gattttctag
     6361 ttcatttgtg gtcatttttt gtactcatat acctttaaga tataaaagga ggttgacatg
     6421 tatcgaattc taaatccaat gaatcacaat gtctcgcttg tcagaaatga taagggagaa
     6481 gaggtgatta taattggtaa ggggattgca ttcggaaaaa ggaaggggga tttgattgct
     6541 gaaaatcagg ttgagaaaat ctttcggatg aagaccgaag agtccagaga aaactttatg
     6601 gctcttctca aagatgttcc gcttgatttt atcacagtga cctatgaaat cattgataag
     6661 ctatcaaaga aatatcatta tccgattcaa gagtatctct atgtaacctt gacagatcat
     6721 atttactgtt cttatcaagc tctaactcaa ggaaggtaca aggatagtaa tctgccggat
     6781 atttccgcta agtatcctgt cgcttttcaa atcgcaaatg aagcttttga aatttaccgt
     6841 cagaagctag cagatcattt tcctgaggac gagattattc ggattgctta tcatttcatc
     6901 aatgccgaag gtgaaaatga agtggaactt gtggagtcga ttgataagag gaaagaaatt
     6961 ctcaggaatg ttgaagaagt gctaaagggt tatgcaattc aacgaaccaa aaaaaataat
     7021 catttctatg atcgctttat gattcatttg aattatttct tggattattt agacagatct
     7081 agagatgata accaatcact tctggatatg gaagatcata ttaaacaatc ctatccaaaa
     7141 gccttcgaga ttggttccaa gatctatgat gtgattacgc aacatacggg tcttgatttg
     7201 tataaaagtg aacgagttta tctagttcta catatccaac gtttattgtc ataaaaattt
     7261 atttaaaact atataaggag aattctatca tgaatagaga agaagtaaca ttgttaggtt
     7321 ttgaaatcgt agcctatgct ggcgatgctc gttcaaaact attggaagcc ttgaaggctg
     7381 ctgaagctgg tgattttgaa aaagcggacg ctctggtaga ggaagctggt agctgtattg
     7441 cagaggctca ccacgcgcaa acaagtctat tgactaagga agcttctggt gaggacttag
     7501 cgtatagtgt gaccatgatg catggccaag accacttgat gacaactatc ttgttaaagg
     7561 atttgatgca ccatttgatc gaactctata agagaggagt taaataatga acaaactaat
     7621 tgcatttatc gagaaaggaa agcctttctt tgagaaacta tctcgtaata tctatcttcg
     7681 tgctattcgt gatggtttca ttgcaggtat gcctgttatt ctcttctcaa gtatctttat
     7741 cttgattgcc tttgtaccaa actcatgggg ctttaaatgg tctgatgaag ttgtagcctt
     7801 tctgatgaaa ccttatagct attctatggg tattctggct ctcttggtag ctggtacaac
     7861 agctaagtca ttgactgact cagtaaaccg gagcatggaa aaaaccaatc aaatcaacta
     7921 tatgtcaacg ctgttagcag cgattgttgg tttgttgatg ttggcagctg atcctatcga
     7981 aagtggtcta gctactggat tcttggggac aaaaggtttg ctttcagcct tccttgctgc
     8041 cttcgttact gtagccatct ataaggtttg tgttaagaac aacgtcacta ttcgtatgcc
     8101 tgacgaagtt ccaccaaata tctcacaagt ctttaaagat gtgattccat tcactctatc
     8161 agtggtttct ctttatgctc ttgatttact agctcgtcat tttgttggtt ctagtgtggc
     8221 agaatcaatc ggtaaattct tcgcaccact cttctcagca gcagacggat accttggtat
     8281 taccattatc tttggtgcct ttgccttctt ctggtttgtg ggtattcatg gtccatctat
     8341 tgttgaacct gctatcgcag cgattaccta tgcaaatgct gaagtcaact tgaaccttct
     8401 ccaacaaggt atgcatgctg ataaaatcct tacttcagga actcaaatgt ttatcgttac
     8461 tatgggaggt actggtgcga cactggttgt tccattcatg ttcatgtggt taacaaaatc
     8521 aaaacgtaac cgtgcaatcg gacgtgcttc agtagttcca actttctttg gtgtaaatga
     8581 accaatcttg tttggtgcac cacttgtatt aaatccaatc ttcttcattc catttatctt
     8641 tgctccaatc gcaaacgtat ggattttcaa attctttatt gaaactcttg gaatgaactc
     8701 attcactgct aatctaccat ggacaactcc agctccacta ggtctagttc ttggaactaa
     8761 cttccaagtg ctatcattca ttcttgctgc ccttctaatc gtggttgacg ttgtcattta
     8821 ctatccattc cttaaggtct atgatgaaca aattcttgaa gaagaacgtt caggtaagtc
     8881 taatgatgaa ttgaaagaaa aagttgctgc aaacttcaac actgcaaaag cggatgctat
     8941 tcttgaaaaa gcgggtgtag aagcagcaca aaatacaatc actaaagaaa caaatgtcct
     9001 cgttctctgt gcaggtggag gaacaagtgg tctccttgca aatgctttga ataaggcagc
     9061 agcagaatac aatgtccctg tgaaagcagc agcaggcggc tatggtgctc accgtgaaat
     9121 gttaccagag tttgatcttg ttatccttgc ccctcaagtt gcttcaaact ttgaagatat
     9181 gaaggcagaa acagataagc tcggtattaa actagcgaaa acagaaggcg ctcaatacat
     9241 caaattaact cgtgatggaa aaggtgctct tgcattcgta caagcgcaat tcgattaagg
     9301 ctagagactc tgaaatagtc tcctatcgtt acggaaatcg ctatggcgaa tttcctatta
     9361 ttaattcgtc ggtaaaaaga tatcgttttt acctcctcat gtcacaattc ggtgacttgg
     9421 tacaagaagt gagatggaga aggatggctc actgactcct ctcctctcac ttttacttta
     9481 tttaaatcaa gaaataggtg aaaaaaatga caaaaacact tccaaaagac tttatttttg
     9541 gtggcgcaac agctgcctat caagcagaag gtgctacaca tactgatggt aaaggaccag
     9601 tagcgtggga taaatatctt gaagataact actggtacac tgcagaacca gccagtgatt
     9661 tttacaatcg atatccagtt gacctcaagc tagcagaaga gtatggtgtc aatggtattc
     9721 gaatttctat tgcttggtca cgtattttcc cgactgatta cggccaagta aatgctaaag
     9781 gtgttgagtt ttatcataat ttatttgcag agtgtcacaa acgtcatgtt gagccttttg
     9841 taactcttca tcactttgac acgccagaag ctctccactc aaatggagac ttcttaaacc
     9901 gtgaaaatat cgaacatttt gtagactacg ctgccttctg ttttgaagaa tttccagaag
     9961 taaactattg gacaaccttt aatgaaattg gaccaatcgg tgatggtcaa tatttggttg
    10021 ggaaattccc tccaggtatc cagtacgacc ttgccaaagt ctttcaatca caccacaata
    10081 tgatggtgtc tcatgcacgc gcggtaaaat tgtacaaaga gaaaggctat aaaggggaaa
    10141 ttggtgttgt tcacgccctg ccaactaaat atcctctaga tcctgaaaat ccagcagatg
    10201 ttcgtgcagc tgagttggaa gatatcatcc acaataaatt catcttagac gcaacttatc
    10261 taggtcgcta ttcagctgaa accatggaag gtgtcaacca tatcttatca gtcaatggtg
    10321 gtagcttgga tcttcgtgaa gaagatttta cagcattaga agctgcaaaa gacttgaatg
    10381 atttcctagg aatcaactac tatatgagtg actggatgga agcctttgat ggagaaactg
    10441 aaattatcca taatggtaaa ggtgaaaaag gaagctctaa gtatcaaatc aaaggtgttg
    10501 gtcgtcgtgt agctcctgac tatgtaccac gcacggattg ggattggatt atctaccctc
    10561 aaggtttgta tgaccaaatc atgcgtgtga agaaagatta tcctaactac aagaagattt
    10621 acatcactga aaatggtctc ggctataaag atgagttcgt tgataacact gtttacgatg
    10681 atggtcgtat tgattacgtg aaacaacact tggagatctt gtctgatgcg attgcagatg
    10741 gagctaatgt aaaaggttac ttcatttggt cattaatgga tgtcttctca tggtcaaacg
    10801 gttatgagaa acgttatggt ctcttctacg tagattttga aactcaagaa cgttatccta
    10861 agaaatcagc tcactggtac aagaaagtag cggaaactca gattatagac tagtagaatt
    10921 agtcattaga tatagaattt tagtgagtca aaaagatgtt caaagatttt atccaatcta
    10981 tttatgaaaa agtttatatt ataaatttcg aaaaatgctc tcaaataccg tgtttgacga
    11041 gtgaagaatt gaaaagtctt ggaaaatggt atgtctcgac tggtaaagaa tggatttgtc
    11101 attcagatga tgagctggaa gaatttaaaa atctattttt aaattttatc aatcctgaag
    11161 gatgggatac tatctccttt gattcagatt ttatgccgtt tcaacaatcg taaccaattt
    11221 ctcaaaaaag ttaaatctta tatttagtac tctgtaaaac tcttatctaa tcacgttgct
    11281 tatactcaat gaaaatcaaa gagcaacttt aaactaggaa gcgagtcgca gatttctcaa
    11341 tgcatagctt tgaggaattg ggcaaaaagt ctttgatata gaaaaacgca tagtatcagg
    11401 tgttgaaaca cctgatacta tgcgttttat tgtgggaaga tttacttttt ttcttctgaa
    11461 attgagttgt tacccaggct ctttcagttt attaaggctt gatgacttta atgtgtttag
    11521 atagcttaaa aaggattgaa tcacttagtt tagaatctga aacaatagta tcaagatttg
    11581 atacattata aaaagtataa aaatcaaact tattgaactt gctatgatct gcgagtaaat
    11641 attttttatt agaattattt aaagcgatgc gttgagcctc tccctcttcc tcgctaaaag
    11701 tagctagagc tccgttttga ataccattac agctaacgaa agctttagaa aattggagat
    11761 tagagagatt ttgtagggtc aatgtaccaa caaaagcacc tgtaatatcg cgataatttc
    11821 cacctattaa aatcaaatct gttaattttc gttcgcttaa aatcagaaaa acaggtagac
    11881 tgttggttac gacgcggata ttgtcaatag gcaactcacg cgcaaaaaac tctaatgttg
    11941 ttcctggtcc aatgaaaata gtttctcttt cttctactag actgcctgca aaatgggcta
    12001 tttcttgttt ttctgccgtt tggagggctt gtttttcaat atttgatcgc tcattagtca
    12061 aaagggagtt ggttcgaagt ttttcagctc caccatgcac acgaatcagc aaatctttat
    12121 cagctaattc ctgtaaatag cgccttgcag tcatatctga aacggctatt tcgtccataa
    12181 tctgtttaac tgttatggtt cctttactat ttactatctc taaaattttg gctaattttt
    12241 cttgtttgag catattatca cctcgtttcc tactactatc ttaccataaa caaactcatc
    12301 attcaaatac aaaaacaaca aaatgaaaca aaaacaaaaa tatcgaagtt tgttttcaaa
    12361 actttcgata tttttgttgg gttataactt tgatgtttct agtttacttt ttgatgattg
    12421 agagtgatgg agaattagtc taaaccgtag ttatagtcat cgtcttgcat ggcttcaact
    12481 tcgccaagaa ggtaaccatt tccgacttga gagaagaagt catggttgga agttcctgtt
    12541 gaaataccgt tcataacgat tgggttgaca tcttcagctg aatctgggaa aagtggatct
    12601 tgtcccatgt tcatgagagc tttattggca ttgtagcgaa ggaaggtttt aacctcttca
    12661 gtccaaccaa caccgtcata aagactctct gtgtagcctt cttcattttc ataaagagta
    12721 tagagtaggt cgtacatcca ttctttgagt ttttcttgct cttcttcagg caattcattg
    12781 aaaccaagtt ggaatttgta accaatgtag gttccgtgaa cagactcgtc acgaataatc
    12841 aatttaatga tttctgcaac gttggcaagt ttgttgttac cgagatagta gaggggagtg
    12901 aagaaaccag agtagaagag gaaggtttcg aggaagacgc tggcaacttt cttttcaagt
    12961 gggctgccgt ttaggtagat ttcgttgaca atctcagcct tcttttgtag gtaaggattg
    13021 gtattggtcc attcgaaaat ttcttcaatc tcagccttag tattcaaggt agaaaagatt
    13081 gatgagtaag atttagcgtg gacagattcc ataaattgga tgttattgaa aacagcttcc
    13141 tcatgtggtg tacggatgtc tgcgcgaagg gcttgaaccc cagtttcaga ttgcatagtg
    13201 tcaagaaggg ttaaaccacc aaaaactttt ccgaccaagt ctttctcttt gttagatagc
    13261 tttctccagt catccaagtc gtttgataag ggaatacgtg tatcgagcca aaattgctcc
    13321 gtcagttttt cccaagttga tttgtcgatg acatcttcga tggcattcca gttaatggct
    13381 ttgtagtaag tttccattta aaatctcttt ctgtgtttag tattgcgaac tcacaattat
    13441 ttctacttta ccataattct ataggagtat cgcacaaaaa gtcggaagcc cgacttttaa
    13501 aatgttacat aaattatgtt atgacatagt agatttgatt ttatcagtgc tgcttaggga
    13561 aaaatagtgt ttctatgcta gaaactaaat cacacagctt tcacattggt tggcgccgac
    13621 ttctccaccg tcatctgtaa aggtacggac gtagtagata gacttgattc ccttgttaaa
    13681 ggcatagtta cgaaggatgg acaaatcacg tgtcgtttgt ttattttccc tcttccattc
    13741 gtaaaggcct tttggaatgt cactacgcat gaagagggtg agtgaaagtc cttgatccac
    13801 gtgttcagtc gcagcagcgt aaacatcgat gactttacgc atatccatat cgtaggcaga
    13861 agtgtagtaa ggaatggttt ctgtagacaa gccagcagca gggtagtaga ttttaccaat
    13921 tttcttctct tggcgttctt cgatacgttg cgtaatcggg tggatagaag cagaaacgtc
    13981 gttgatatag ctgatagaac catttggcgc tacagcaagg cgattttggt ggtaaagacc
    14041 atcttcttga accttgtcgc gaagttcagc ccaatcagca acaccaggga taaagacatt
    14101 tttgaagagt tctttaacac ggtctgatgt tggaacaaat tcaccagtta catacttgtc
    14161 aaagtaactt ccgttagcat agtctgattt ttcaaagttg tggaaggtaa taccacgttc
    14221 acgcgcaata ttgtttgact ctaccaaggt ccagtagttc ataagcataa agtagatgct
    14281 tgtaaattca acagactcag gtgaaccata ttcaatgagt tgttgggcaa ggtagctgtg
    14341 cagtcccatg gcaccgagac caaaggtgtg ggcttggcta tttccatggt caatcgttgg
    14401 tacagctacg atatgtgaac tatctgtaac gaaagtaagg gcacgaacca tagcacggat
    14461 agaacgacca aaatcaggtg aagtcatcat gttaaccacg ttggttgaac ccaggttaca
    14521 tgaaacatct gttcccattt gaaggaattc ttgagcatcg ttgatcaagc ttggttcttg
    14581 aacttgaaga atctcagaac acaagttact catgataatc tttccatcaa caggatttgc
    14641 acggttagcc gtatcgatgt tgactacata aggatagcca gactcttgtt gcaatttaga
    14701 gatttcagtt tccaaatccc gcgccttgat ttttgtcttg cgaatatttg gatttgcgac
    14761 caattcatcg tatttttcag taatgtcgat gtaattgaat ggcacaccgt attctttttc
    14821 tacagagtaa gggctgaaga ggtacatttc ttcattttta cgagccaatt cgtagaattt
    14881 atcaggtact acaacaccaa gtgatagagt cttgacacgt actttttcat cagcgttttc
    14941 tttcttagtt gaaaggaaag cgatgatatc tgggtgaaag acgttgaggt agacaacacc
    15001 ggcaccttga cgttgcccca attggttgga gtaagagaag ctgtcttcaa aaagcttcat
    15061 aacaggaacg acacctgaag cagctccttc atagcctttg ataggtgcac cagcttcacg
    15121 aaggttgctg agggtaattc ccacaccacc accaatacgt gaaagttgaa gagctgagtt
    15181 gatagaacgt ccgatagagt tcatatcatc cgtcacttgg attaggaaac aagataccaa
    15241 ctccccacgg cgagcacgtc cagcattcaa gaaggaagga gtagcaggtt ggtagcgttg
    15301 gtggatgatt tcattggcaa tatcgattgc aacagcttca ttcccatcag cgaaataaag
    15361 ggcgttgaag aagacacggt cttccatatt ttcaagatag tattcaccgt cattagtctt
    15421 taaggcatat tgattgtaaa atttataagc tgccatgaat gacttgaatt ggaagttttg
    15481 gtctttgata aattgagcca attcttccaa gaactctgga cggtatttct tgataaaggc
    15541 tgtttcgatg tagttgtgtt caatgaggta attgattttg tctttgattg aatcaaaaac
    15601 catagtgttt ggaactacat tttctttaaa gaaagcatcc aaggcttcct tgtctttatg
    15661 aagcatgatt tgtccattaa caggacggtt aatttcgtta ttaagacgga agtaagtcac
    15721 gtcttcaaga tgttttaatc ccataaaatt tcccttatct aattacaaaa gaaaggcttc
    15781 taagttagcc ctaaaagcag ttttttctgg atgatgtact aagattatgc taattgcttc
    15841 agttttcctg gttggaaacc tgaaaagact tcagttggtg tttggataac aggagctgcg
    15901 ctaaaaccga gctctttaac ttgatcgacg tactcaggtt gctcatcaag attgatttca
    15961 cgataagaga cattattact gtccaagaaa cgcttggtca ttttacattg gacacaattg
    16021 tttttagaat aaacggttac cattgtgtaa ctcctcttca aaatttaata ctatcttagt
    16081 atatcagaaa ataaaatttt gtcaatgatt tgaactaaat atagtggtgt tcttttgttg
    16141 tttttatata taaacacaat atatagtgtt tgtgttgtga aatagcaatg attatcctat
    16201 aaattgtttt tgaagaaact atatcctgtg ttttgttatc taggatagaa gattttcagc
    16261 aagttatctg aaaggaaatt gaaggaaaat ccagaaaatg cttgaaaaaa atcctagaag
    16321 atggtataat actaaattgt aagggttatc acatataact caaaaaaaga aagaacaaaa
    16381 ggagagtcaa actatggctt ctaaagattt ccacgtagtg gcagaaacag gtattcacgc
    16441 acgtccagca acattgttgg tacaaactgc tagcaaattt gcttcagata tcactcttga
    16501 gtacaaaggt aaatcagtta accttaaatc aattatgggt gttatgagtc ttggtgttgg
    16561 ccaaggtgct gacgtaacta tctcagctga aggtgcagat gcagatgacg ctatcgctgc
    16621 aatctcagaa acaatggaaa aagaaggatt ggcataaggg aaatgacaga aatgcttaaa
    16681 ggaatcgcag catctgacgg tgttgcagtt gcaaaagcat atctactcgt tcagccggat
    16741 ttgtcatttg agactattac agtcgaagat acaaacgcag aagaagctcg ccttgatgcc
    16801 gctctacagg catcacaaga cgagctttct gttattcgcg agaaagcagt aggtacgctc
    16861 ggtgaagaag cagctcaagt ttttgatgct cacttaatgg ttcttgctga cccagaaatg
    16921 atcagccaaa tcaaggaaac tatccgtgcg aagaaagtga atgcagaagc aggtctgaaa
    16981 gaagttacag atatgtttat cactatcttt gaaggcatgg aagacaaccc atacatgcaa
    17041 gaacgcgcag cggatatccg cgacgtgaca aaacgtgtat tggcaaacct tcttggtaaa
    17101 aaattgccaa acccagcttc tatcaatgaa gaagtgattg tgattgcgca tgacttgact
    17161 ccttcagata cagctcaatt ggacaaaaac tttgtaaaag cttttgtaac caacattggt
    17221 ggacgtacaa gccactcagc tatcatggca cgtacacttg aaattgctgc tgtattaggt
    17281 acaaacaaca tcactgaaat cgttaaagac ggtgacatcc ttgctgttaa cgggatcact
    17341 ggagaagtga ttatcaaccc aacagatgaa caagcggcag aatttaaagc agctggtgaa
    17401 gcctatgcga aacaaaaagc tgaatgggca cttttgaaag atgctcaaac agtgactgct
    17461 gacggtaaac acttcgagtt ggctgccaat attggtactc caaaagacgt tgaaggtgtt
    17521 aacaacaacg gtgcagaagc tgttggactt taccgtacag agttcttgta catggattct
    17581 caagacttcc caactgaaga tgagcagtat gaagcataca aggctgttct tgaaggaatg
    17641 aacggtaaac ctgttgtcgt tcgtacaatg gatatcggtg gagataagga acttccttac
    17701 ttcgatatgc ctcacgaaat gaacccattc cttggattcc gtgctcttcg tatctctatc
    17761 tctgagactg gagatgctat gttccgcaca caaatccgtg ctcttcttcg tgcgtctgtt
    17821 cacggtcaat tgcgtatcat gttcccaatg gttgcgctct tgaaagaatt ccgtgcagcg
    17881 aaagcagtct ttgatgaaga aaaagcaaac cttcttgctg aaggtgttgc agttgcggat
    17941 aacatccaag ttggtatcat gatcgagatt cctgcagcag ctatgcttgc agaccaattt
    18001 gctaaagaag ttgacttctt ctcaattggt acaaacgact tgatccaata tacaatggca
    18061 gcagaccgta tgaacgaaca agtttcatac ctttaccaac catacaaccc atcaatccta
    18121 cgcttgatta acaatgtgat caaagcagct cacgctgaag gtaaatgggc tggtatgtgt
    18181 ggtgagatgg ctggtgacca acaagctgtt ccacttcttg tcggaatggg cttggatgag
    18241 ttctctatgt cagcaacatc tgtacttcgt acacgcagct tgatgaagaa actcgacaca
    18301 gctaagatgg aagagtacgc aaaccgtgcc cttacagaat gctcaacaat ggaagaagtt
    18361 cttgaacttc aaaaagaata cgttaatttt gattaatcga aaaatccctg caactcagtt
    18421 acagggattt ttttgatatt ttaaaaagaa ttttcaagaa aatctttctt atagaaagtc
    18481 caaccttgaa aaagtagtgg tcagaacaaa aaatacttaa atggttcata aaattcttga
    18541 caagttggag atttaggagt aaactattaa ccagttaagt aatagagagg agtttctgca
    18601 atttagaaat gaattgcaac tagaaatatc aaatagaaag agagtttcga tgaaaattaa
    18661 taagaaatac cttgttggtt ctgcggcagc tttgatttta agtgtttgtt cttacgagtt
    18721 gggactgtat caagctagaa cggttaagga aaataatcgt gtttcctata tagatggaaa
    18781 acaagcgacg caaaaaacgg agaatttgac tcctgatgag gttagcaagc gtgaaggaat
    18841 caatgctgag caaatcgtca tcaagataac agaccaaggc tatgtgactt cacatggcga
    18901 ccactatcat tattacaatg ggaaggttcc ttatgacgct atcatcagtg aagaattgct
    18961 gatgaaggat ccaaactacc agctaaaaga cgaggatatt atcagtgaaa tcaagggtgg
    19021 ttatgttatc aaggtagatg gaaaatacta tgtttacctt aaggatgctg cccacgcgga
    19081 taatgtccgt acaaaagaag aaatcaatcg gcaaaaacaa gaacatagtc agcatcgtga
    19141 aggagggact tcagcaaacg atggtgcggt agcctttgca cgttcacagg gacgctacac
    19201 cacagatgat gggtatatct tcaatgcatc tgatatcatt gaggacacgg gtgatgctta
    19261 tatcgttcct cacggcgacc attaccatta cattcctaag aatgagttat cagctagcga
    19321 gttggctgct gcagaagcct tcctatctgg tcgggaaaat ctgtcaaatt taagaaccta
    19381 tcgccgacaa aatagcgata acactccaag aacaaactgg gtaccttctg taagcaatcc
    19441 aggaactaca aatactaaca caagcaacaa cagcaacact aacagtcaag caagtcaaag
    19501 taatgacatt gatagtctct tgaaacagct ctacaaactg cctttgagtc aacgccatgt
    19561 agaatctgat ggccttattt tcgacccagc gcaaatcaca agtcgaaccg ccagaggtgt
    19621 agctgtccct catggtaacc attaccactt tatcccttat gaacaaatgt ctgaattgga
    19681 agaacgaatt gctcgtatta ttccccttcg ttatcgttca aaccattggg taccagattc
    19741 aagaccagaa gaaccaagtc cacaacctgc accaaatcct caaccagctc caagcaatcc
    19801 aattgatgag aaattggtca aagaagctgt tcgaaaagta ggcgatggtt atgtctttga
    19861 ggagaatgga gtttctcgtt atatcccagc caaggatctt tcagcagaaa cagcagcagg
    19921 cattgatagc aaactggcca agcaggaaag tttatctcat aagctaggag ctaagaaaac
    19981 tgacctccca tctagtgatc gagaatttta caataaggct tatgacttac tagcaagaat
    20041 tcaccaagat ttacttgata ataaaggtcg acaagttgat tttgaggctt tggataacct
    20101 gttggaacga ctcaaggatg tcccaagtga taaagtcaag ttagtggatg atattcttgc
    20161 cttcttagct ccgattcgtc atccagaacg tttaggaaaa ccaaat
//
LOCUS       DAVLZG010000035        20167 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLZG010000035 DAVLZG010000000
VERSION     DAVLZG010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20167
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.035"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(85..1026)
                     /locus_tag="VYO72_001257"
     CDS             complement(85..1026)
                     /locus_tag="VYO72_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1707629.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VYO72_001258"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VYO72_001258"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1707630.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(2952..3032)
                     /locus_tag="VYO72_001259"
                     /pseudo
     CDS             complement(2952..3032)
                     /locus_tag="VYO72_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3074..3304)
                     /locus_tag="VYO72_001260"
     CDS             complement(3074..3304)
                     /locus_tag="VYO72_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707631.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(3322..3963)
                     /locus_tag="VYO72_001261"
     CDS             complement(3322..3963)
                     /locus_tag="VYO72_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1707632.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(3975..4709)
                     /locus_tag="VYO72_001262"
     CDS             complement(3975..4709)
                     /locus_tag="VYO72_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1707633.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(4712..4909)
                     /locus_tag="VYO72_001263"
     CDS             complement(4712..4909)
                     /locus_tag="VYO72_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707634.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(4909..5115)
                     /locus_tag="VYO72_001264"
     CDS             complement(4909..5115)
                     /locus_tag="VYO72_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707635.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(5125..5439)
                     /locus_tag="VYO72_001265"
     CDS             complement(5125..5439)
                     /locus_tag="VYO72_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707636.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(5706..5783)
                     /locus_tag="VYO72_001266"
                     /pseudo
     CDS             complement(5706..5783)
                     /locus_tag="VYO72_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5780..7069)
                     /locus_tag="VYO72_001267"
     CDS             complement(5780..7069)
                     /locus_tag="VYO72_001267"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1707637.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(7147..8394)
                     /locus_tag="VYO72_001268"
     CDS             complement(7147..8394)
                     /locus_tag="VYO72_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1707638.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(8585..9436)
                     /gene="rgg"
                     /locus_tag="VYO72_001269"
     CDS             complement(8585..9436)
                     /gene="rgg"
                     /locus_tag="VYO72_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1707639.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            9560..9901
                     /locus_tag="VYO72_001270"
     CDS             9560..9901
                     /locus_tag="VYO72_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1707640.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            9959..10039
                     /locus_tag="VYO72_001271"
                     /pseudo
     CDS             9959..10039
                     /locus_tag="VYO72_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10155..11858)
                     /gene="ilvD"
                     /locus_tag="VYO72_001272"
     CDS             complement(10155..11858)
                     /gene="ilvD"
                     /locus_tag="VYO72_001272"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1707641.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(12091..13023)
                     /locus_tag="VYO72_001273"
     CDS             complement(12091..13023)
                     /locus_tag="VYO72_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1707642.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(13020..13877)
                     /locus_tag="VYO72_001274"
     CDS             complement(13020..13877)
                     /locus_tag="VYO72_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1707643.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(13881..15227)
                     /locus_tag="VYO72_001275"
     CDS             complement(13881..15227)
                     /locus_tag="VYO72_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1707644.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(15240..15524)
                     /locus_tag="VYO72_001276"
     CDS             complement(15240..15524)
                     /locus_tag="VYO72_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1707645.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(15528..17558)
                     /locus_tag="VYO72_001277"
     CDS             complement(15528..17558)
                     /locus_tag="VYO72_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1707646.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            17749..18756
                     /locus_tag="VYO72_001278"
     CDS             17749..18756
                     /locus_tag="VYO72_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1707647.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            18759..18959
                     /locus_tag="VYO72_001279"
     CDS             18759..18959
                     /locus_tag="VYO72_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1707648.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            19111..19293
                     /gene="rpmF"
                     /locus_tag="VYO72_001280"
     CDS             19111..19293
                     /gene="rpmF"
                     /locus_tag="VYO72_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1707649.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            19309..19458
                     /gene="rpmG"
                     /locus_tag="VYO72_001281"
     CDS             19309..19458
                     /gene="rpmG"
                     /locus_tag="VYO72_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1707650.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(19938..>20167)
                     /locus_tag="VYO72_001282"
     CDS             complement(19938..>20167)
                     /locus_tag="VYO72_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707651.1"
                     /translation="KDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTVSG
                     KWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         6425 a         4326 c         3531 g         5885 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacataca tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcatgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accaacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggcattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgcttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tctttctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggttactga ctccgtcagt tctatccaca acctcaaaac agtgttttga gcaacctgcg
     3001 gctagcttcc tagtttgctc tttgattttc attgagtata atacaaaaat ccgatgaact
     3061 tcaccggact cttttatttt gaatttttgc ctgctttacg cttttcagcg atttcggctg
     3121 cctttcgagg caagacaatt tccgttatgt aagccgtccc aaaacgcagt acacctgcaa
     3181 taggagcaaa gacaactgct agatagttat agaagaaatc gcctttgaag gcataagcta
     3241 gcgctccaat gatgaaaaat agaacgactg cctgaatcac tgctaataaa attactcgtt
     3301 tcatgtgacc tcctgactct attatagcat gagaatcatc aaaaagccga ctaaattatt
     3361 caaagcgtga agagaaatac tgtagaccag accttttctg ctaatgtaag ccaaacccaa
     3421 actaaaacca aggctaaaat agacaaaaaa ttgttgcaca tcacctggaa aatgaatcaa
     3481 ggcaaataga agactagata ccagaagaaa aatcagggtt cgtttactat tgtcctgctt
     3541 aggaaagaga tagcgtgcta acatccctct aaaaacaatc tcttccgtca aaggagcaaa
     3601 aataaccaca gcaaagaatg agaaaagtgg ttgagacaag gtcaagtctg tcgctatttg
     3661 ctgatttact gaaggatcat ctggcaagaa gaattgaacg accagagata agaaccaaac
     3721 caaggcagga agccaaataa atcggttaaa gccgctcttc tcaatataaa caggagcttt
     3781 ctgataccat ttgtaaatgc cgtacacata tactccagcc aagaccacat agagtagagt
     3841 aacagcatag ggtgaagcgc ctaaagcaag cgacgcagtc gcgagcccct gaataaagcc
     3901 atagataaag aaaaaggata gaagggctag aagaatccag ccaaggtttt taagtaattt
     3961 catagataac tcctttattt gaaataacgt tttaccatag gtaactgcat cacattgata
     4021 taaacatgga tggctcctac aagcaagaaa gctagtaact gaatctctcc tgtcaagaaa
     4081 gaaatgataa taagaaaaat atataaggct ggtaagacat attggtgtaa ttggaataaa
     4141 attcgaaaac tctgttccaa attagcctga cgctcccctt catcataaga atttatatag
     4201 ttcaagacat cctttggtgt agcgaaaaat tccaaatcaa actgacgaac aatcgcaatg
     4261 gttttaaaaa gagatttttg agcgactaag aataccacaa agagtaagaa agaaaggaaa
     4321 aatgtttgag ggtttgtatg caatataatc acctcactta atgaaataaa aatagccaat
     4381 ggaatcgcta cacctgtaat attaaaagca atggttccaa actcaagatt ccgatacatt
     4441 tgcacataat aggtttcatt cagatcgtca tccatttcct cttgatacaa ggaatgaaat
     4501 tttctgcttt tctttaagaa attgaaagtc aaaaacatac taatgaaacc tatcagtaaa
     4561 caaatagctg atatccatgg catcaaggct tttacatcta aaataatttc gtgggattcg
     4621 acacgtgcct taaacatccc tacaaacatg cccaagaacc cccccaagac aatagacatc
     4681 aaaaataaca atctacgttt ctttttcata ttcattctcc tttttcactt gctagatttt
     4741 tggatttctt ttcaatccat tcagttactg ggatgagagc aaagtagacc caaacaaatt
     4801 ggtcgctttg atagggatta aaccagctta ggtccatccc aatcagtaga aatacgctga
     4861 ctaataaagc tatgaccact acataataaa tcactttata cttgttcatc actcgtcctc
     4921 ctccaaacga aataccgatt cgactgtttc gttgaaaatt tgagatattt tcagggcaat
     4981 gataatggat ggggtgtact catcccgttc tagtaggcta atggtctgtc tggaaacccc
     5041 tgccagtttg gctaggtcgg tttgattgag accatcgcga gctcgaagct cttttagacg
     5101 attttttagt tgcatgttac acacctactc tccgtcaaat tcaacggttt ggatatcttc
     5161 aatacgttgc aacttgaatt tttctttccc ctttttatca acactacgta gtttgaccca
     5221 ttcctcgtca acatccacaa cttcccagtt atctggccca atatacactc ccgttataat
     5281 tggttccttt ccaatcattt cttgcaataa tctcgacatt tctgcgtttc ctttctcttt
     5341 tcgctcaagt tttttgattt tattctctag tttcttgatt tttttagaat tattagaata
     5401 aaagaaaatc ataaatagta taaatactag tacccacatt ataactcctt tctgcttcct
     5461 atttcttaac ttgaattcat tgtaacacat ctttttcttt ttgacaatta tagttgtcaa
     5521 aaagtttatg atttttgtca ttttgcaaaa gaaaaaggtc aggagtaagt tcctgaccac
     5581 tttatctatc attaatactc ttctaaaatc tcttcaaacc acgtcagctt caccttgccg
     5641 taggtatagt tactgacttc gtcagtttca tctacaacct caaaaccatg ttttgagctg
     5701 acttcgtcag ttctatccac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc
     5761 ctagtttgct ctttgatttt cattgagtat aaaatcctag tttttcaaag atttctgaga
     5821 agttttggct gattgtctca agtgacactt gcacttcttc tcgggtttgg ttgttcttga
     5881 ccgtcacttg tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccgcaa
     5941 agacatctgc tgacttgaac tgagctttga gcttacggtt gaggtaatca cgctctgctt
     6001 tgaaaccttg ttggcgaaga gcttggacta gttctagggc tttgacattt gctccatcac
     6061 ccaagactgc gatatagaca tctagggcgt tttcgatagg gagggccacg ccttgttttt
     6121 caaggatgag aagcaggcgc tctacaccaa gcccaaaacc aaatccagca gtttcagggc
     6181 ctccaaagta agcaaccaaa ccatcgtagc gaccacccgc acagactgtc aagtcattgc
     6241 cctcaatctc tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca
     6301 tattggtatc gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa
     6361 aatgagtttg gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcca
     6421 ccttgtcttc tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt
     6481 ggctatcctt agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt
     6541 aggctgcacg gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac
     6601 cgatttcctt caaaaaatgg gctgccataa cgattgtttc cacatcggta gctggattgc
     6661 tagagccaaa acactcaaca ccaatctggt ggaattggcg caagcgccct gcctgtggac
     6721 gctcataacg gaacataggt cccatgtagt agaacttgct tggcttttgc acttctgggg
     6781 cgaagagttt attttccaca taggaacgga caacgggcgc agttccttct ggacggaggg
     6841 taatatggcg gtcacccttg tcatagaaat cgtacatttc cttggttacg atatccgttg
     6901 tatctccgac agagcggctg ataacctcgt aatgctcgaa aataggcgta cgcacttctg
     6961 cgtagttgta gcgcttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag
     7021 actcagcagg taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc
     7081 tttaaactta atagtcttat tttaccataa atagagggat taaaacagtg agaaaaaaat
     7141 taggatttag atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag
     7201 accaacaaat agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc
     7261 tgttcccaca ggtatggata aggtaaacaa tagatctaaa aaattactag tacgagctag
     7321 aacctctgga gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga
     7381 cacatacaga gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc
     7441 caaaccaact agactaagtc ctacagtcgc ccacatcatc aatctaggca aggactgctt
     7501 cccaaaataa gcattgcccg taaggctact gatgatgatt gctactaaaa cacagaattg
     7561 attgataaat agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat
     7621 attataaatt ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat
     7681 aaaaccaaag tttttctgcc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt
     7741 taggaactgg tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga
     7801 cattgacagg ctcaatttgc tttttcctaa aaagaggata gtggctgata ctaggaaaaa
     7861 gcaggcattg attcccgcaa cgagagaaaa attgttgacc gatagagcta agagccagac
     7921 tccgaaagct tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc
     7981 ctccatcaga tcatcttcag ctactttttc cttaataaga ggcatacgca ggccacctgc
     8041 aaaatcactg atgatatcac taatgacatt gatcaaacac aggctagaaa aggcaaagag
     8101 actagcttgc tgaacaacta gggctgctag aaaaaataga accgcctgaa acaaaccgct
     8161 atagaccatc catttgacct tgtccctcgt gtaatctgcc cgaatccctg caaaaactgt
     8221 aaagaaggtc ggaagaatca tgacaatatt cgccatagca acagcaaaag atgcttgtga
     8281 caaggtcgat gcatagacga taaagaccag gttgaaaatc gaagcaccaa aagcattgaa
     8341 gaagcgtgat aaagtcaaaa ttctataagc tggatttcta aacaatagtt tcatagataa
     8401 tctccctcct tgttctaagt tctacatcaa gaatagcttt agtatagcac ttatgaattt
     8461 gcgaaacgat tcttttgaat atatgcaaca aacaaaatga gcaaaaaaac gatagaactt
     8521 ttgtaatgac ctgagagagg gtaacagttc tatcgcttca aattttttct tggtttgcag
     8581 atactcaaca ttcggtcgta tttctatagt attcggcaga tttattacag ccaagcatct
     8641 caaaaatacg gacagcatcc tccatctttt tctggccttc cttgactcta ccttgcttgc
     8701 tatcaaggag accttctgcc cacagataaa caattcggaa ataggtctca ttttccttgt
     8761 agaaatgctc ttcgataaca cgtttaaaat aataggcatt ggtaaattct tcacactcaa
     8821 tactagctaa aaagccattc aatagtatag tatgaaaaag gtttcgattg ccagacattt
     8881 ccattagaaa atcagattta cgtaccattt ctcgtacata tctagtaaaa agagaaacag
     8941 ataaaaatgg agaactgact gaaaataaat tgagttcata gattccccag atctcggtag
     9001 aaaacaaata atcatgaagg acttttcctt cctctgctgt taactctacc ctttcatcta
     9061 tgctcttcat ataagacttg ataataatgg catttagaat atgtttctgt ttgttgtgag
     9121 aatgggcatg cttttgatac tccctgcgat ataagtcctc aagaggtgct atattctttg
     9181 gttccaagac atctgtaatt tcttttctca actcagaatc tgtatcatac tggaaacctc
     9241 tcgccagaaa gaggatctcc tccacactgg cagatatatt ttccagagca aatagaaact
     9301 tttccaccaa aagctcactc tgacctgttt caaaacggga caacatagac ggcgaaaatt
     9361 gtcctccggt tgcttgtctc agtgagatat ttcttgactc tcgtaattgt ctaaagactt
     9421 ttccaatctg ctccatagac ttccccttga ttccgtattt tcttcatttt atcatatttt
     9481 tcagaaaatt catcaaaaac ttgccaaatt gtcagaatta tgagaaaata gaggatattt
     9541 atcacgtgga gggactgcta tgagagacga tatcaaaatc aatgaccgtg ctttggcctt
     9601 gcaagaccaa attatcgaaa aactagagaa agtttttgat acagatgtgg aattggatgt
     9661 ttacaatcta ggtctgattt atgaaatcaa tctggatgaa acggggctct gcaagattgt
     9721 catgaccttc accgatactg cctgtgattg cgccgaaagc ctgcctattg aaatcgtggc
     9781 aggtctgaaa caaatcgagg gtatcgaaga tatcaaggtt gaagttacct ggtcgcctgc
     9841 ttggaaaatc acacgaatca gtcgctatgg ccgtattgcc cttggactac cacctcgtta
     9901 agcaggccaa tcacttttaa agatgaaaaa agcaagccga aaatggcttg ctttttgata
     9961 ctcaatgaaa atcaaagggc aaactagaaa actagccgca ggttgctcaa aacactgttt
    10021 tgaagttatg gatagaactg acgaagtcag ctcaaaatac tgttttgagg ttgtggatag
    10081 aactgacgaa gtcagtaacc atacctacgg caaggcgacg ttgacgtgat ttgaagagat
    10141 tttcgagtat gagtttattt tttacctgac ttgtccatat tccagaagtc tgtcacggct
    10201 ccgcgtgaag cagatgatac gatgtgggca tatttaccga ggacaccacg gctgtaaagt
    10261 ggtggcaagg ttgtttctgc cttgcgtttt tcaagttctt cttcggatac ggccatggaa
    10321 atttctttgg tatcttggtc aaccgtaacg atatcgccgg tacggagata ggcaattggt
    10381 ccaccatcct gagcttcagg agcgatatgt ccaacaacca gaccataagt accaccagag
    10441 aaacgtccgt ccgtcaagag ggccacctta tctccctgac ctttaccaac aatcattgaa
    10501 gaaagtgaca gcatctcagg cataccagga ccacctttag gtccaacaaa acgaacaacg
    10561 actacatcgc catcaatgat ttcatctgtc aggacggcct gaatcgcatc ttcttctgag
    10621 tcaaagacct tagctggccc aacgtgacga cgcactttaa cacctgatac cttggcaact
    10681 gcaccgtcag gagcaaggtt cccgttcaag atgataagcg gaccatccgc acgttttgga
    10741 ttttcaagtg gcatgataac tttttggcct ggagtcaagt ctgcaaagtc agccaagttt
    10801 tcagctacag tcttaccagt acatgtgatg cgatctccgt gaaggaaacc atttgccaac
    10861 aagtacttca taaccgcagg gacaccaccg acttcgtaga ggtcttggaa gacatactga
    10921 ccagatggtt tcaagtcggc caagtgaggc acacgttctt gaatcgtatt gaagtcctca
    10981 agtgacaagt caacatttgc ggcatgggca atggcgagca agtgaagagt ggcgtttgta
    11041 gaaccaccga gagccatcgt tacagtaata gcatcttcaa aggcttcacg agtcaagata
    11101 tctgatggtt tgagaccaag ttccaacatc ttaacaacag cacgtcctgc tgcttcgata
    11161 tcttctttct tatcagctga ttcagctggg tgagaggatg accctggcaa actcatccct
    11221 agaacttcga tagcagttgc catggtatta gcagtataca taccaccaca accaccaggg
    11281 ccagggcagg cattacattc aagacgtttc acgtcctcag ctgtcatgtc accgtggttc
    11341 cattttccga taccttcaaa gacagaaacc aagtcgatat ctttaccatc aagatttccc
    11401 ggtgcaatag ttccaccata ggcgaaaata gctgggatat ccatattagc aatagcaatc
    11461 atagatccag gcatgttctt gtcacagcca ccgatagcga cgaaggcatc cacgttgtga
    11521 ccactcatag ccgcctcgat ggagtccgcg atgatgtcac gagatgttag agagaaacgc
    11581 ataccaggcg ttcccatagc gatcccgtcc gctacggtaa tggttccaaa ctgtacaggc
    11641 caagcgcctg cagatttgac accttcttta gccagtttcc cgaaatcatg caagtgaatg
    11701 ttacatggtg tattttccgc ccaagtcgaa atcactccca caatcgatgt ttcaaagtcc
    11761 ttatctgtca taccagtcgc acgaagcata gcacggttag gtgatttaac catgctgtca
    11821 taaatgctac tgcggtgacg tttatctaat tcagtcatct tatccctccc atttcagttt
    11881 ttactattat agcacaattt aaaggcaatg aacagaataa aattcttgaa ttttcagaaa
    11941 attctatacg catgtgaaat atttaaaatt aaaaacaaca aagcggatta gtgcactttc
    12001 tgatgaccag aatatgcttt ttaatccgct ttctttaaat aacgtactgt aatttttaca
    12061 gaaattcttt cagataagtg tatttaacat ctatcttgca ttataaattt ctagaacctt
    12121 ctcttttata ttcgattcac tcaaaccata ctcattaaga agataatcca ttttccctac
    12181 ttgaccgaat ctttcttgaa cacccatccg atgaattttt gttattccat catcagagaa
    12241 taattcacat aaagcactgc caattccacc tatctgattg tggttttcta cagtaaatat
    12301 agtttttcca cttaacattg tttttatctg ttctggtatc ggtttgattc taaataaatc
    12361 tatcacacct actgaataac ctaatttaga cagttcatct gcaactcgaa tacttggagc
    12421 aaccattatg ccagaagcaa cgattacaag atcttcacca tgtcttaact caatgtagcc
    12481 cttagaaaaa tcttctccac cttgatatac agcctctgga gcttttctaa ttgttcgaat
    12541 atattttagt ccttttaagt ctaatgtctg attcaatatt tcacgaaatt ggatatcatc
    12601 agttgcttca aaaatgattg atttaggaat taaacgtaac aatccaattt cttcaaatgg
    12661 catatgtgtc ccaccattca tttctgcagt tactcctgca tctgatccaa tcacagtggc
    12721 atccaattgt gcgtatccaa gagaaataaa taattgatca aatactcttc gtgaagcaaa
    12781 aggaccaaat gtatgaagat aaggtctaaa cccctgaata gacaagcctg ctgcaaggcc
    12841 gaccatttct gcttccataa tcccaacatt cacataacgg tctccaaagt tcttttcaag
    12901 attattagta gccatcgaac ttgacaaatc ggcttctaag actactatat cagaataact
    12961 ttgattagcc tctaaaagga agtctctata tacatgccgt aattctttcg tacttctcat
    13021 cattctgttt cctccaattc ctgacttaat ctttctacaa ctgaagttaa catttgtttc
    13081 tcctctacag tagggcgaag atgatgattg gatttcattt cttccagctc ttgaacccct
    13141 tgacctttaa tagtatctaa tacaatgcac ttaggtgatg aattatttga ctgttttaat
    13201 tggacaatcc cttcataaat ttctctaata tctgaaccct tgaccctaat ggattcaaat
    13261 ccaaatgctg aaaatttttc tacgaaatca cctggattac aaatatcctt tgtaaaacca
    13321 tctaattgtt ttttgttatc atcaacaaat acaattaagt tggataactg ttgatgagaa
    13381 gcaaactgta tagcctccca acattgtccc tcatttaact caccatctcc aacaatagca
    13441 taagtataaa agggactctt tcttattctc tgaccatatg caagtccagt tgcaacacta
    13501 attccttgtc ctaaagagcc cgttgtcata tctatgcctg gcgttagatt tctatcagga
    13561 tgagacggta atttggttcc atttgtattt aaagaatata agaattcttt gtcaaagaaa
    13621 ccattcaaat agagtgtact gtatagagct ggtcctccat gaccttttga taatatgaaa
    13681 taatctctat ctcgtgctgc aaatatttct ggagtcattg gcattatttc accataaagc
    13741 actgctaaaa cttctacgat agacagactt cctccgtaat gtccgaatcc aagatgattc
    13801 aatgttctaa gagtatttaa tcggatgtta gtcgcaaatt ttcttaaccc atcttctcta
    13861 tttttactta aaatcatccc ttattcctcc tttgcagatg gctttttaat aaaggatact
    13921 ccaaacataa ctgctagaat aagaacaaga ccaatcacaa tacctgcttg tgagccaaat
    13981 tgatttaaca ttcctaaaat aattcctgat agaccaaaat ctgcatctga gaaagttgat
    14041 ccttggaaac caagtcctcc caaaactggc attaaaaaga ctggaagaaa actgattaaa
    14101 ataccttgta aaaatgctcc aatagtggcg ccacgaacac caccagatgc attcccaatg
    14161 acacctgcag tcgctccaca gaagaaatga ggcacaacac ctggtaagat aacaaccgtt
    14221 cctgaagcaa tcataattgc catacttact aaaccaccaa caaaactaga gataaatcca
    14281 attagaactg cattgggtgc ataagtataa acaatcggac aatccaaagc aggttttgaa
    14341 ttaggtacaa gacgctctga aataccttta aaggctggaa caatttcgcc caaaataagg
    14401 cgaacacctg ctaaaataac aaatacccct gctgcaaatt gacctgctaa ttgtaaagca
    14461 taaactagac cacttgtacc actactgatt tctttttcta tatattctga ccctgcaaag
    14521 atagctacaa taatgtaaat aactgccata gataaagtga tactaacagt actatcacgt
    14581 aaaaaagcta aactctttgg aaatttaatg tcctctgttg attttgattt gtcaccgata
    14641 aggctaccag taaaaccact caaccaatat cccaaagaac tgaaatgacc taaagccacc
    14701 ttgtcatttc cagttaattg aaccatatat ttttgcacaa atgctgggga aatactcata
    14761 ataataccga gtgctaatcc tcctagtaag atgagaggca agctagtaaa gccagcaact
    14821 gataaaatga ccgcaatcat acatgccata tatagagtgt ggtgccctgt taaaaaaata
    14881 tatttaaatc gagtaaaacg agcgattaag atattgaaca ccatgcctgc aaacataatc
    14941 attgcagtag ctgagccata tgttgttaaa gctacagcta caattgcttc attattcggc
    15001 acaacgccag ataaatgaaa agcatgctca aacatggtac caaatggatt taaagaattt
    15061 tgtacaattc ctgcaccacc agatacaact aagaaaccaa caaaggtctt aattccacct
    15121 ttaataatat caggtaattt cttcttctga agaactaatc ctaaaattgc aattaaagct
    15181 actaaaatag ctggtgtact aacaatatcc aatatgaact tcatcatgac gctagcctcc
    15241 tatataagtc ctttttcttc acaaagttta gtaattaatt ctcgtagttc atccatatca
    15301 ataatactat ttaagatacg aacatctcca agatgactag ctgaatcagc tagatcacga
    15361 ccaacaatcc aaatatcagc tgcatttgga tctgctccac ctaaatcata atgttcaact
    15421 tctacatccg aaacattcaa atcactcaat acagattcaa tattcatctg taccataaaa
    15481 cttgaaccta atcctgaacc acaagctgta ccaattttta acattatcta atcctcctgt
    15541 ttaattatca ttttaatgtc atcatagttt tttgatgata ttaaagtttg aacatgattt
    15601 ttatctctta aaattgttgt taaatgtgac aaagccttta aatgactctc attatcaatg
    15661 gctgcaatac aaatcaacaa tcttacctct tgttctggat tatccaataa ataaatcggt
    15721 tcttccaaaa ctaacattga cattcctatt tcattcacac cttcatctgg ccgagcgtga
    15781 ggaattgcta ctcccttccc taaattaata aaaggtccaa actcttctac tttttgaatc
    15841 attgcctcag ggtagttctc agttatctta tcttgatcca aaagcggttt agctgctaaa
    15901 cgaatcgcct ccttccatcc taatttttgc gaactaacct gataggtttc tttggtaata
    15961 agttgttcta gcactggtac aatttccttt ctatcatttt tttggtaaag ataattcttt
    16021 aacgccaatc ttaattccaa ttcttgtgta ataattccat atcttttgac aatattcagg
    16081 atttgttcaa tctcaaaatc tccatactct aaattcggaa aatcttttaa cactagttct
    16141 actagttgta ttgcttgctc ttcagtcatc ataaccgaaa ctagataatt tggcttttct
    16201 gtctccacct ttatggtaga aaaaaccata tcatagtcac tactagcttt cacctgtaaa
    16261 tcatcaatct ttgaggttcc tataaactca atttgaggaa ataatgctaa tagattctct
    16321 tttaacatca atgaagaact aacaccatta ggacaaatga ttgctgcttt atagcatttt
    16381 tgaggcaaag tatctgcttt ctttaaataa cctccgaaat ggataacaaa atatgctgtt
    16441 tcactatcag gtatgggatt gtcaatagcg tccatcaagg gcatcaaaga atctttgact
    16501 aattcaaata aatcaggata atgttcttta acatgcaata catattcatt tgaactaggt
    16561 aggccgaact ttaatctata gtaagccggt ataaggtggc ggcgaagatt ttctctcaat
    16621 ccttcccttt gtttaaaatg taacaaagaa atatcttcca ttctacttat aatagcctct
    16681 gttaattgat taaagtaaac cggagcaaca tctacttcac cttcaaagca acttgataat
    16741 aaaactgtga tatagcgata atcatcctca gaaaacaccg tatctataat tcccaaatca
    16801 accactgtat ccaataaaat agtggttata tcttgaataa caggagatac taatgtctct
    16861 gaaagacata ctctttcaac atccctttga tacctacaca gaatgaatac taaaccgaaa
    16921 aggcaaactt ttaattgatt aacaataggt actagttgta gcttctcata ataatcttta
    16981 actacctgat ttatcaaatc ataagttaat gaataccccc aactggataa aacataatcc
    17041 aaaccccaaa tccctatgga ggattccagc aactcactaa ccatttgaaa agctaagcgg
    17101 tgcttattcc actctgaacc gtgtaaagta taaccttttg ctctactgta ccctagctcc
    17161 aaatcattat ctaacataat ctttcttaat gattgaatat cagataaggt tgtattctta
    17221 cttactttca aaaagtcttg gtaatgatta ttcgatataa aatctaatcg gcaaaaagtg
    17281 taaagataga ttaaagctaa gcgagtcgac tttggtaaaa ccaattcatc cgacttaata
    17341 atatctgtca aagactgctt cgtacgattt gataaactat agcgaccttg ttttttatcc
    17401 agcactatcc ctttattagc tagataaggc actaaataat ctattccttc tttgacttcc
    17461 tttataggta agctcacctt aacagataat tcatataatg atagctcaca atgatccatc
    17521 aaagtcatca aaataactag tgctctataa tcaaacattt ctcttccttt ctaactacaa
    17581 ttatagtgta aaaattataa gaataaaaga gtatttgagc acaatataat ctcacctttt
    17641 aaaagaaatt attgggctga aagtttttag tgattatttt caactttcta ttgactttta
    17701 aaaacaaagt gatatcattt agatatcaaa taatgggagg tcattcttat gactgaaaaa
    17761 ctaatcaatt caaaaccaaa tggtgtattc gcattgattc tcattgagtt gacaatcgta
    17821 cttggtgtct ttatatttat aatgggtgtt ggttcggaaa acatttttgg aattattatc
    17881 ggacctttac taatcgtaat tgcaggtcta gctcatgctg gtttaaaagt tgtcaaacct
    17941 caggaagctc tggttctgac actctttggt aattatacag gtaccatcaa agaacctggt
    18001 ttttactttg tcaatccctt cagcgtagca gtcaaccctg caaaccacac tcgacttgga
    18061 caaagtggtg atgttagcac aaaatctcct tttttaggag ctaaatcatc aaatgacaat
    18121 gatgtaaatc ttgaaattgg caagaaacac atttccctca aagtcatgac cttgagcaat
    18181 tctcgtcaaa aaatcaatga ttgcttagga aaccctgtag aaatcggtat cgcggtaact
    18241 tggagagttg tcgataccgc taaggcagtc ttcaacgttg ataactacaa agaatatctt
    18301 tcactgcaat gtgatagcgc cctccgtaat attgtccgca tctatcctta cgatgtgtct
    18361 cctaatgtgg atactacggg tgacgggcaa gcagatgaag gtagtctccg tggctctagc
    18421 gaaattgttg ctaaccgtat tcgtgaagaa atccaaagtc gtgttgagga tgctggcttg
    18481 gaaatccttg aagcacgtat cacttaccta gcttatgctc cagaaattgc tgccgttatg
    18541 cttcaacgcc aacaagcatc tgccattatt gatgcacgta agatgattgt agatggtgct
    18601 gtaggaatgg ttgaaatggc actagaacgg ctcaatgaag gggaattggt agaacttgac
    18661 gaagaacgaa aagctgccat ggtttcaaat ctccttgtcg ttctttgtgg caatcatgat
    18721 gcacaaccaa ttgtcaacac aggaagtctt tactaaagat ggctgaagct aaaaaaaagc
    18781 agatccccct tcgactctca acaaagttat acgctgcact cgcatcatgg gcagaagacg
    18841 actttcgttc agtcaatggc caaatcgaat atctcctcac agagtgtgtc aagcaacgga
    18901 agaaagacgg aaaatacgta tcagaaacca ttgacgaacc atttgagatt gatatttaac
    18961 accttctcct gtctgccgtg tcggatagga gaattttttc atcttttttt gtcaagtaac
    19021 tttactttac aaaaaaaatg tgttatccta gtatggttga tgaaaatcag tagattgaat
    19081 cgaatataaa tacctaaagg agaaatcaaa atggcagtac ctgcacgtcg cacttcaaaa
    19141 gcgaagaaaa acaaacgtcg tacacactac aaagtaacag ctccatctgt aaactttgac
    19201 gaaactactg gagattactc acgttctcac cgtgtatcac ttaaaggata ctacaaagga
    19261 cgtaaaatcg ctaaagctgc atcagctgaa taatagaagg gagataccat gcgcgtaaat
    19321 attacacttg aacacaaaga atctggtgaa cgcttgtacc ttacttctaa aaacaaacgt
    19381 aacactccag accgccttca attgaagaaa tactcaccaa aacttcgcaa acacgttgtg
    19441 tttacagaag tgaagtaagc attcaatacg aatcaataca gaagaaaaac gcttgatcag
    19501 cgttttttct ttttgttaat ttcactatat tgcaagagaa atcattcgaa tgactacatt
    19561 ttttgaaata agaatacgga ttcggacgat taaaagtaag agaaactcaa atgtaagttg
    19621 gggttccttt tttgtatatt tttcaaataa cgcctctaca ctatttgtag caaattcacc
    19681 aactacagtt gcatcttagt taaaataagt tagaatatgt aagtgagtac cagatatacc
    19741 aagacatcgt caccatctaa ggtatattca aaatacaaaa gttgaccaac tagatttctg
    19801 aatatcctta tatatccatt cttaaaattg gtttaaatag cgtagtcttt taaactagtt
    19861 ttgagaatcc aaaaaatctt cctacatatg taagaagatt ttttagttca gaatgattag
    19921 atttagctaa tggataccta tcctacccac tcaccgttag cattgactcg atagccatcg
    19981 ggtgtagtcg tgtttactaa taaatctcct gaattatagg tatagtacca tttaccagaa
    20041 actgtaaacc aaccagtagc cattgaacct gattcattta agtaatacca taagcctttg
    20101 tctttaaccc aaccagtagc cattgaacct gattcgttta agtaatacca taagcctttg
    20161 tctttaa
//
LOCUS       DAVLZG010000036        19250 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLZG010000036 DAVLZG010000000
VERSION     DAVLZG010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.036"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            241..934
                     /locus_tag="VYO72_001283"
                     /pseudo
     CDS             241..934
                     /locus_tag="VYO72_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            988..1377
                     /locus_tag="VYO72_001284"
     CDS             988..1377
                     /locus_tag="VYO72_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1707652.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(2038..3066)
                     /gene="queA"
                     /locus_tag="VYO72_001285"
     CDS             complement(2038..3066)
                     /gene="queA"
                     /locus_tag="VYO72_001285"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1707653.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            3217..3924
                     /locus_tag="VYO72_001286"
     CDS             3217..3924
                     /locus_tag="VYO72_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1707654.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            4002..4511
                     /locus_tag="VYO72_001287"
     CDS             4002..4511
                     /locus_tag="VYO72_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707655.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSKADMEEMV
                     NYIINHYEE"
     gene            4591..4767
                     /locus_tag="VYO72_001288"
     CDS             4591..4767
                     /locus_tag="VYO72_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1707656.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            4897..5832
                     /locus_tag="VYO72_001289"
     CDS             4897..5832
                     /locus_tag="VYO72_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1707657.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            5825..6613
                     /locus_tag="VYO72_001290"
     CDS             5825..6613
                     /locus_tag="VYO72_001290"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1707658.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            6614..6997
                     /locus_tag="VYO72_001291"
     CDS             6614..6997
                     /locus_tag="VYO72_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1707659.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            7013..7402
                     /locus_tag="VYO72_001292"
     CDS             7013..7402
                     /locus_tag="VYO72_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1707660.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            7486..8616
                     /locus_tag="VYO72_001293"
     CDS             7486..8616
                     /locus_tag="VYO72_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1707661.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            8621..9358
                     /locus_tag="VYO72_001294"
     CDS             8621..9358
                     /locus_tag="VYO72_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1707662.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            9369..10142
                     /locus_tag="VYO72_001295"
     CDS             9369..10142
                     /locus_tag="VYO72_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1707663.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            10132..10749
                     /locus_tag="VYO72_001296"
     CDS             10132..10749
                     /locus_tag="VYO72_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1707664.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            10959..11360
                     /locus_tag="VYO72_001297"
     CDS             10959..11360
                     /locus_tag="VYO72_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1707665.1"
                     /translation="MITLFLSPSCTSCRKVKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            11360..11638
                     /locus_tag="VYO72_001298"
     CDS             11360..11638
                     /locus_tag="VYO72_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1707666.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            11628..12401
                     /locus_tag="VYO72_001299"
     CDS             11628..12401
                     /locus_tag="VYO72_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1707667.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            12402..13706
                     /locus_tag="VYO72_001300"
     CDS             12402..13706
                     /locus_tag="VYO72_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1707668.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            14280..15158
                     /gene="pstS"
                     /locus_tag="VYO72_001301"
     CDS             14280..15158
                     /gene="pstS"
                     /locus_tag="VYO72_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1707669.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            15158..16075
                     /gene="pstC"
                     /locus_tag="VYO72_001302"
     CDS             15158..16075
                     /gene="pstC"
                     /locus_tag="VYO72_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1707670.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            16065..16949
                     /gene="pstA"
                     /locus_tag="VYO72_001303"
     CDS             16065..16949
                     /gene="pstA"
                     /locus_tag="VYO72_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1707671.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            16960..17763
                     /gene="pstB"
                     /locus_tag="VYO72_001304"
     CDS             16960..17763
                     /gene="pstB"
                     /locus_tag="VYO72_001304"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1707672.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            17776..18534
                     /gene="pstB"
                     /locus_tag="VYO72_001305"
     CDS             17776..18534
                     /gene="pstB"
                     /locus_tag="VYO72_001305"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1707673.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            18546..19199
                     /gene="phoU"
                     /locus_tag="VYO72_001306"
     CDS             18546..19199
                     /gene="phoU"
                     /locus_tag="VYO72_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1707674.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
BASE COUNT         5657 a         3492 c         4410 g         5691 t
ORIGIN      
        1 gcaatccttt atatatgaga ttgattacga tatagttaaa gtgttagttc aataatcaat
       61 atatcattct aagtctattt tatatataaa gtatattgtt taacgtttga tagaaaagat
      121 gctatactag aagtaggatg taatggcaaa atctaatact aataagcgct atgcaatacg
      181 taaactcgga aagatttttg gttctgcggt aatcgggcta actttatttt taggaggaat
      241 ctgaatacaa gttttgttca tgctgctgat gggattcaat atgtcagaga tgatactaga
      301 gataaagaag agggaataga gtatgatgac gctgacaatg gggatattat tgtaaaagta
      361 gcgactaaac ctaaggtagt aaccaagaaa atttcaagta cgcgaattcg ttatgaaaaa
      421 gatgaaacaa aagaccgtag tgaaaatcct gttacaattg atggagagga tggctatgta
      481 actacgacaa ggacctacga tgttaatcca gagactggtt atgttaccga acaggttact
      541 gttgatagaa aagaagccac ggatacagtt atcaaagttc cagctaaaag caaggttgaa
      601 gaagttcttg ttccatttgc tactaaatat gaagcagaca atgacctttc tgcaggacag
      661 gagcaagaga ttactctagg aaagaatggg aaaacagtta caacgataac ttataatgta
      721 gatggaaaga gtggacaagt aactgagagt actttaagtc aaaaaaaaag actctcaaac
      781 aagagttgtt aaaaaaggaa ccaagcccca agttcttgtc caagaaattc caatcgaaac
      841 aaaatatctc gatggcccaa ctcttgataa aagtcaagaa gtagaagaag taggagaaat
      901 tggtaaatta ctcttactac aatctatact gtagatgaac gtgatggaac aattgaagaa
      961 actacttctc gtcaaattac taaagagatg gtaaaaagac gtataaggag agggacgaga
     1021 gaacctgaaa aagttgttgt tcctgagcaa tcatctattc cttcgtatcc tgtatctgtt
     1081 acatctaacc aaggaacaga tgtagcagta gaaccagcta aagcagttgc tccaacaaca
     1141 gactggaaac aagaaaatgg tatgtggtat ttttataata ctgatggttc catggcaaca
     1201 ggttgggtac aagttaatgg ttcatggtac tacctcaaca gcaacggttc tatgaaagtc
     1261 aatcaatggt tccaagttgg tggtaaatgg tattatgtaa atgcatcggg tgagttagcg
     1321 gtcaatacaa gtatagatgg ctatagagtc aatgataatg gtgaatgggt gcgttaacag
     1381 attcctccct gcgacaaaat tgataatagt atgtctgaat atataattat atataaaaag
     1441 ctatagataa ggtcatctta tagcgactat aaaaaagtga acaagcctag tcttctgtac
     1501 attagaattc agatttgttc actttttgtt taatactcaa tgaaaatcaa agagcaaact
     1561 agaaaactag tcgcaggttg ctcaaagtac tgctttgagg ttgtagatag aactgacgaa
     1621 gtcagtcaca tatataatcc aaggtgacgt tgacgcggtt tgaagagatt tttgaagagt
     1681 ataagtcttt gattttgaga ctaaggagag tcagggtcaa agtagtgaat gattctgaaa
     1741 taactcataa tagtctcttg agaggacaga taagagtaac aaatatggtg ctactcatgt
     1801 gtcttgcatt ttgatttaca aacagcgaag aaaatatagg aagctgaaat aaaatataga
     1861 tgaatcaatt tggagagtca acgcaatcta tggcaatatt ttcgaagcta gggggaagca
     1921 ttttaatttc aatgtactag gcctcttcta cagctagcta gagtttcaat tgtagatgtt
     1981 ctttgaaata atatcttagc gatttattgg tattagaaga tttagagaaa ttctttctca
     2041 ataaataaac atggcgtcac caaaactgaa gaagcggtag tgttcttgga tggcatggtg
     2101 gtaggcatct aagactaatt cacggcctgc aaaggcagaa accaacatga ccagagttga
     2161 ttttggcagg tggaagttgg ttgagaaggc atccacgacc ttccactcat acccaggttt
     2221 gataaagata ttggtccaac cagaatctgc ttggatttgc ccatcaaact tggaaccaat
     2281 agtttccaag gtgcggatag aagtggttcc gacagcgatg acacgaccac cattttcttt
     2341 gacagagcga agggtggcag cagcttcctc agaaagttga tagaactctg agtgcatttc
     2401 gtgttcgtcc agattatcca cagaaacagg tctaaaggtt ccgagtccga catggagagt
     2461 cagatagact agatgaacac ccttagcttg gatttctgcc agcagttctt tggtgaagtg
     2521 aagaccagca gtcggtgctg cagcagagcc gctttccttg gcgtagacgg tttgataacg
     2581 ttcacggtca tctaattttt cgtggatata aggtggcaga ggcatttctc ccagactttc
     2641 caagacttct aggaaaattc cttggtattc aaagcggaca atgcgtcccc cgtgggtcaa
     2701 ttcttctgta acgacagcgc tgaggcggcc atcaccaaag ctgatacgag taccgacctt
     2761 gaggcgtttg gcaggtttag ccagaacttc ccactcgtct ccactagtgt tcttaaggag
     2821 gagaagttcc acatgacctc ctgtctccac tttttgacca tagaggcggg cagggagaac
     2881 tcgggtgtcg ttcatgacaa gggcatcacc aggttccagc atatcaataa tagagtggaa
     2941 gtgtttatct tgcatttctc ctgtctcacg gttgacgatg aggagtttgg aggcatcacg
     3001 tttttcaagg ggcgtttggg caatcaattc ctctggcaag tggaaatcaa aatcagctgt
     3061 attcatatat ttgttcattc tttctaagtt ctaatcctat ccattataac acgtttcaag
     3121 tttggacgct ctttttttag aaattaaatc gttttcactt gacaaaaatt ggtctatacc
     3181 atataataaa tatagacaga aatggaggat gaaaagatga aagttattaa agttgaaaac
     3241 caagttcaag gtggaaaagt tgcttttgag attttgaagg aaaaattggc taatggagct
     3301 caaactctag gacttgcgac aggaagtagc ccacttgaat tttacaagga aattgttgag
     3361 agtgaccttg atttttcaaa tctaaccagt gtcaaccttg atgagtatgt gggccttgat
     3421 ggggacaatc cacagtctta tcgttacttc atgcaagaaa acttgttcaa ccaaaaacca
     3481 tttaaagaaa gtttcttgcc tcgtggtgtt aaggacaatg ctgaagctga agttgaacgc
     3541 tacaaccaaa ttttggctga ccatccagtt gacctccaaa tcttgggaat cggtcgcaat
     3601 gggcatatcg gctttaatga gcctggtact ccatttgaca gtcaaacgca tctagtagaa
     3661 cttgaccagt ctactatcga agccaatgca cgcttctttg ccaagattga agacgtccca
     3721 acccaagcta tttcaatggg gattaaaaac attttggatg ccaagtctat tattcttttt
     3781 gcttacggtg agtcgaaagc agaagccatt gccggaacag tatctggccc agtgactgag
     3841 aacctacctg caagtagcct ccaaaatcac cctgatgtaa ccatcatcgc agatgctgaa
     3901 gcgcttagct tactcgaaaa ataaaaagta taagaaccgc ttgctctttg gagtgagtgg
     3961 ttttagacat ataaaacttc aacttaactt taggaggaca catgaataaa gaagaatttt
     4021 taaaaataaa agaagcatat aagagtgcta gaacggaaga aagaaaaagt ataataggct
     4081 tcattacaaa aaagaaagat aaggagggga attttctttt tactaagtca aaagataaac
     4141 catataccac aagaaatcaa tattcaggag gcggaggaaa taaaaagtac acctcgggta
     4201 gtagattatc taggccatat gatttatcaa atcacatgtg gattgatttg tcatataaag
     4261 gaaatgacat cttaatctct ttacagtctt ttgatattga tccaaatagt aaagaacttc
     4321 acgtcttata tgatagaata ggcatcttat ttgaacaatc taaaaaaatt ccaattttta
     4381 aagattgcta tacaataact aaagtcagtg atgcttttct taaaatggaa acaacaaact
     4441 gggaattacc tttatctaaa gcagatatgg aagagatggt gaactatatt attaatcatt
     4501 atgaagaata aaaaacttag tttcctcttg acaattattc cttttacgtg tagaatgaaa
     4561 tagatattga acttgaaggg agtgaaaaaa atgtctaaaa cagtagtacg taagaatgaa
     4621 tctcttgacg acgcacttcg ccgtttcaaa cgtgcggtta ctaaagctgg tactcttcaa
     4681 gaaacacgca aacgtgaatt ctatgaaaaa ccttctgtaa aacgtaaacg taaatcagaa
     4741 gtagctcgta aacgtaaaaa attctaattg aaatgaaagg ctagagaaat ctagtccttt
     4801 ttcttttaaa taaatactcc aaagcctgca aaaatctgaa acttcctcct acaatttgat
     4861 ataatagaga gaagaactca tttgaaggag gaaatgatgt cggttttagt aaaagaagtg
     4921 attgaaaagc ttagactaga cattgtctat ggtgaaccag aattgcttga aaaggaaatc
     4981 aatatagcgg atattacgcg acctggtctt gaaatgacag gctattttga ctactataca
     5041 ccagagcgga ttcaactttt ggggatgaag gagtggtctt atctgatcag catgccttcc
     5101 aacagccgtt atgaagtttt gaaaaaaatg tttctacctg agacaccagc agtcattgtt
     5161 gcccgtggtt tggtggttcc agaggagatg ttaaaggctg ctagagaatg taagattgct
     5221 attttaacca gccgtgcagc taccagtcgt ttatctggag agttatctag ctatctggat
     5281 tctcgtttgg cagaacgtac cagtgtgcac ggtgtcttga tggatattta tgggatgggc
     5341 gtcttgattc agggagatag tggaattggt aagagtgaga caggtcttga gcttgtcaaa
     5401 cgtggtcacc gtttggtagc cgatgaccgt gtcgatatct ttgccaagga tgagattact
     5461 ctctggggtg aaccagctga aattttgaaa cacttgattg aaattcgtgg ggttggtatt
     5521 atcgatgtta tgagtctcta cggtgcgagt gctgtcaagg attcttcaca ggttcagctt
     5581 gctgtctatt tggaaaatta cgatacgcat aagacctttg atcgtcttgg aaacaatgca
     5641 gaggaacttg aagtttctgg cgtagccatt cctcgtattc gtattccagt taaaacaggt
     5701 cgtaatatct ctgttgtgat tgaggcagct gccatgaatt atcgtgccaa ggaaatgggc
     5761 tttgatgcga cccgtttgtt cgacgaacga ctgacaagtc tcatcgctcg aaatgaggtg
     5821 caaaatgctt gatccaattg ctattcaact aggaccccta gccattcgtt ggtatgcctt
     5881 atgtattgtg acaggcttga ttcttgcggt ttatttgacc atgaaagaag cacctagaaa
     5941 gaagatcata ccagacgata ttttagattt tatcttagta gcctttccct tggctatttt
     6001 aggagctcgt ctctactatg ttattttccg atttgattac tatagtcaga atttaggaga
     6061 gatttttgcc atttggaatg gtggtttggc catttacggt ggtttgataa ctggggctct
     6121 tgtgctctat atctttgctg accgtaaact catcaatact tgggattttc tagatattgc
     6181 ggcgcctagc gttatgattg ctcaaagttt ggggcgttgg ggtaatttct ttaaccaaga
     6241 agcttatggt gcaacagtgg ataatctgga ttatctacct ggctttatcc gtgaccagat
     6301 gtatattgag gggagctacc gtcaaccgac tttcctttat gagtctctat ggaatctgct
     6361 tggctttgcc ttgattctga tttttagacg gaaatggaag agtctcagac gaggtcatat
     6421 cacggccttt tacttgattt ggtatggttt cggtcgtatg gtcatcgaag gtatgcgaac
     6481 agatagtctc atgttcttcg gacttcgagt gtcccaatgg ctgtcagttg tccttatcgg
     6541 tctcggtata atgatcgtta tttatcaaaa tcgaaagaag gccccttact atattacaga
     6601 ggaggaaaac taaatgttag aagttgcata tattcttgtt gccttagctt tgattgtctt
     6661 tttggtctat ctgatcatta ctgtacaaaa gcttggtcgt gtcatcgatg aaacagaaaa
     6721 gacgattaaa accttgactt cagatgtgga tgtgaccttg catcacacca atgagttgtt
     6781 ggctaaggtc aatgtcttgg cagatgatat caatgtcaag gtggctacga ttgatccact
     6841 cttcagtgct gttgcagatt tatctctatc tgtttcagac ctcaatgacc atgcgcgtgt
     6901 cttgagcaag aaagcttcat cagctggttc aaaaacactc aagactggtg caagtctgtc
     6961 agctcttcgt cttgcaagta aatttttcaa aaaataaaaa aggagaatcc ttatgggtaa
     7021 attatcctca atccttttag gaacggtttc aggtgcagct cttgccttgt ttttaacaag
     7081 tgataagggc aaacaagttt gcagtcaggc tcaagatttt ctagatgatt tgagagaaga
     7141 tccggagtat gccaaggagc aagtctgtga aaaactgaca gaagttaagg agcaggctac
     7201 agattttgtt ctgaaaacaa aagaacaggt tgagtcaggt gaaatcactg tggacagtat
     7261 acttgctcaa gctaaatcct atgcttttca agcgacagaa gcatcaaaaa atcaattaaa
     7321 taatctcaag gaacaatggc aagaaaaagc cgaagctctt gatgactcag aagagattgt
     7381 gattcatata acagaagaat aaaccatcac catctccgga cggactatgt atctggggat
     7441 ggtgattttt atctggaatc tagtctttgt ggtataataa ttactatgca gaaaaaacca
     7501 acgtcagcct atgtgcacat cccattttgt acccagattt gttattattg tgatttttca
     7561 aaggtcttca tcaaaaatca gccagtcgac agctatttag agcatctgct ggaagagttt
     7621 cgttcttatg atattgaaaa gttgtcaacc ctttatatcg gtggtggaac accgacagcc
     7681 ctgtcggctc cgcaactgga ggtgttactg aatggcttga ctaaaaactt ggatttgtct
     7741 gtcttggaag agttgaccat tgaagccaat ccaggcgatt tggatgcgga taagatagct
     7801 gttttgaaaa attcggctgt caatcgtgtt tcgctaggtg tccagacctt tgatgataag
     7861 atgttgaaaa agattgggcg cagtcatttg gagaaggata tttatgaaaa tatcgatcgc
     7921 ctgaaactgg ctggttttga caacatctcc attgatttga tttatgctct gcctggtcag
     7981 accatggagc aagtaaagga aaatgtggct aaagccattg gattggatat tccccacatg
     8041 agtttgtata gtttgatttt agaaaaccat acggtcttta tgaaccggat gcgacgtggg
     8101 aaattgcctc tgcctaagga ggaactagaa gcggagatgt ttgagtacat cattgcagag
     8161 ctggagcgag cgggttttga gcattatgag atttctaatt tctccaaacc cggttttgaa
     8221 agtcgtcata atctcatgta ctgggacaat gctgaatact atggtattgg tgcaggggca
     8281 tctggttatg tcaatggagt acgctataaa aatcatggtc ccattcgtca ttatctcagt
     8341 gcggttgagg aaggcaatgc ttgtattaca gaagatcacc tgagtcaaaa ggagcaaatg
     8401 gaagaagaaa tgttcttggg actccgcaag aaatccgggg tttccatggc gcgatttgag
     8461 gaaaaatttg gacagtcttt tgctggactt tatggagaaa ttgtcagaga tttggttcaa
     8521 caaggcctca tgcagattga gggtgaccac gttcgcatga caaagagagg tctctttttg
     8581 ggagatactg tagcagaacg atttattttg gagtaggatc atgggcttaa cttatcaaat
     8641 gaaaatgaaa attccttttg atatggctga tatgaacggt catatcaaac ttccagatgt
     8701 gattttgctg tcactgcaag tttcagggat gcaatcgatt gaactgggag ttagtgataa
     8761 ggccattttg gaagactata atctggtctg gattatcgca gaatatgata ttgaggtggt
     8821 tcgtttgcct cgttttgcgg aagaaattac catcgaaacg gaagccttga gctacaatcg
     8881 acttttttgc taccgtcgct ttactattta taatgaagcg gggcaggagc tcatccatat
     8941 gatggcgacc tttgttctca tggaccgcga cagtcgaaaa gtccatgctg ttgaacctga
     9001 gattgtggct ccttaccagt ctgattttga taaaaaactt atccgtggac cgaagtatga
     9061 atccttggaa gagccgatca gcaaggatta ccatgttcgt ttttacgact tggatatgaa
     9121 tggtcatgtc aataacagta aatacttgga ctggattttt gaggtcatgg gagcggattt
     9181 tttgacccac tatattccca agaaaatcaa cctcaagtat gtcaaggaag ttcgaccagg
     9241 tggggtgatt acatcggctg ttgaacggac tggactggaa agcaagcatg aaattacaag
     9301 tgatggggtt atcaatgccc aagcaatcat tacttggcaa gaaataaaaa aggtttaggg
     9361 agaaatagat gaaatataaa ggctatttaa tcgatttaga cggaaccatt tataagggga
     9421 aagaccgaat ccctgctgga gagacttttg ttcatgaatt gcaaaagcgg gacattccct
     9481 atctctttgt aaccaacaat acaacccgca ctccagagag tgttaaggag atgttggctc
     9541 agaattttaa tatcgatacg cctctatcga ctgtctacac agcgactttg gcaaccatcg
     9601 actatatgaa tgatttgggg cttgaaaaga ccgtctatgt cgtcggagaa gcaggactca
     9661 aggaagccat caaggcggct ggttatgtgg aagacaagga aaaccctgcc tacgtggtag
     9721 ttggtctgga ttggcaagtc gactatgaaa aatttgccac agcaactctt gctattcaaa
     9781 agggtgccca ttttatcgga accaatcctg acctcaacat cccgacggaa cgtggtcttt
     9841 tgccaggtgc tggctcactg attacgctgc ttgaagtagc gacacgagtg aagccggttt
     9901 atatcggaaa accaaatgcc atcattatgg acaaggcggt tgagcactta ggtttggaac
     9961 gtgaagagtt aatcatggtt ggggacaatt atttgactga tatccgggct gggattgaca
    10021 atggcattcc aacactcttg gtgacgacag gttttaccaa ggcagaagaa gtagctggcc
    10081 tgccaatcgc accgacacat gtggtttcta gccttgcgga gtgggatttt gatgaaaact
    10141 aaattgacct tttggggctc tatgctcttt ctcctctccc tctcaatcct tctgaccatt
    10201 tatctggctt ggattttcta tcctatggag attcagtggc taaacttaac gaatcgagtc
    10261 tatctaaaac cagaaaccat tcaatacaat tttcatatct tgatgaatta tctgaccaat
    10321 ccttttagtc aggtcttaca gatgcctgat tttcgttcgt cagcagctgg tctgcaccat
    10381 ttcgcagtgg tcaagaatct ctttcatttg gttcagctag tagctctagt gacactgcca
    10441 agtttctatg tctttgtcaa taggattgtg aaaaaggact ttttgtctct ttatcgaaaa
    10501 agtctcctga ctctagtagt cttacctgtg atgattggac ttgggggagt tttgattggt
    10561 tttgaccaat tctttactct tttccatcaa attctctttg tgggagatga tacctggctt
    10621 tttgatccag ccaaggatcc tgttattatg attttgccag agaccttctt tcttcatgcc
    10681 ttcctcctct tttttgccct ctatgaaagc ttctttgggt atctgtgtct gaaaagtcgt
    10741 aggaagtgaa atgaaagatg tttttaattt gcatatataa aaatatatat cgtttaaaac
    10801 catcgttaag agtgaattaa ccaaatccaa ttgtgtcaat cgttcgcaaa cagcctattt
    10861 ttcttgaaaa aataggcttt ttttctaaaa atccctagtc aagcgcctta tttttttgta
    10921 taatagaagt agcaaagtat agataagaag agaaaagcat gattacacta tttctatcac
    10981 cgagctgtac atcatgtcgt aaggttaagg cctggttaga aaaacataag gttccctttg
    11041 tggaacacaa tattatgacc agtcctttaa caagaaaaga attgcaacac atcctttcct
    11101 tgaccgaaaa tggtactgat gacatcattt caactcgttc aaaaattttt caaaaattga
    11161 atattgatgt agagagtatt tcggtatcgg aattgcttca tttgattgag cagtatccta
    11221 gtcttttgcg tcgtccaatt attattgatg ccaagcgtat gcaaatcggt tttaatgaag
    11281 atgagattcg tgcttttctc cctcgtagtt atcgtaagca agaactaaaa gaagcaagaa
    11341 tgagagctgg tattagttaa tgaacaaaca gtatagttac ccactagatt tgtcgtggag
    11401 cactgaagaa cttgcttcag tgctttcttt ttttaatgat gttgaagctg cctatgaagg
    11461 caaagtagag gctaaaaagt tactggactc ctataaggga ttcaaagcgg tcgtgccaag
    11521 caagagcgaa gagaaacgtt tgggacgaga atttgaaacg gttagtggct attcacttta
    11581 ccgagcagtt caggctgcca aagaaaaagg ggaaggaaag atttctcttg gaaagtaaat
    11641 ttgaatttgc taaagagctt gttaagaaag caggccagta cattcttgac catatgcagg
    11701 aagacttgcg tgttgaaacc aagtcctctt caacagattt ggtgaccaga ctggacaaag
    11761 aagttcagga actcttggtt ggtgagattt tgtcccgtta tcctgaggat aagatttgtg
    11821 ctgaagaagg ttgtctgcga gcctcggttc aagagggcaa ggtttgggtc attgatccca
    11881 ttgatggtac caataatttt gtagcccagc aggaagattt tgctgttatg atggcttatt
    11941 ttgaaaatgg tcagggacag tttggtctga tttatgatgt ggtcaaaggg gattgttacc
    12001 acggtggtgg ggaatttcca gtttgtctaa atgataggcc cctagctcct tttaaaacta
    12061 aaccacttgg agattttctc attgcaggga atagtggtat gctggaaacc aatgaatggg
    12121 ggctggctga tttgagccga tcggttcttg gtgttcgtgt ctatggaagt gcggccatta
    12181 gttttgccaa gattttgtca gggcgtttgt tgacctatct cacttatctg caaccatggg
    12241 attatgccgc agctagtatt ttaggggaaa gtctgggcta tcgggttgtg accctttttg
    12301 gtgaagctcc tgattttcaa accagacagc cggtcatgat ggtgcctctt gagatgcagg
    12361 aggaaattca gtcctatatt tacgaaagga aaagaactta aatgcaattt ccagaaggat
    12421 ttgttgaaaa atataaagag atactaggag atgaggcaag agattttctt gcctcttttg
    12481 aggaggaagc ggtttcggcc tttcgggtca atcccttaaa agaagagcaa ctttcctttt
    12541 ctgatgccat tactcaaacc ccttggggcc actatgggaa ggtttcaggg aaatcgcctg
    12601 agcatgctac aggtttagtt tattcgcaag aacctgctgc tcaaatggtg gctcaagtag
    12661 cccaacccag tcctggtatg aaggtcttgg acttggctgc tgcaccgggg ggcaaatcaa
    12721 ctcaactggc agcctatcta gcaggtgagg ggctacttgt ttccaatgaa atttcaagca
    12781 aacgggctaa gattttggtt gaaaacatgg agcgttttgg agcgacaaat gtcgtggtga
    12841 ccaatgaatc tgccgaccgc ttggtcaagg tctttaaagg ctattttgac ttaatcgttc
    12901 ttgatgcccc ttgctctggt gaaggaatgt ttcgtaagca acctgatgct atggactatt
    12961 ggagcttaga ttatccgagt caatgtgcta gcttgcaaag agaaattctg gaggatgcag
    13021 tgaccatgtt agctgaaggt ggtcgtctgg tttattcgac ctgtacctgg gcacccgagg
    13081 aaaacgaaga gattgtcaat tggttgctgg aagagtatga ttttgacttg ttgccagtag
    13141 agcatatcaa tggaatggta gctggtattg acctgccaga aacggctcgg atgtaccctc
    13201 atcagtttaa gggagagggt cagtttgttg cccatctaca gtttaagggt aacaatccag
    13261 ctcctaaatt taaggcaagt aagagtaacc tcagccgtga acaagttgcc ttgtggcagg
    13321 aatttgccca aaaccatttg aaggtcaatc taccgggtat cttgcagact tttggagacc
    13381 agctttatct cttgccagaa cttttgccag atttagggaa gctcaagatt gctcgcaatg
    13441 gactgcatct gggcactttt aagaagaaac gctttgagcc cagtttcgct cttggtttag
    13501 ccttgaaacc gagtcaggtc gaacagtcgg ttgaaattgg ccaagaagcg tttgtcaagt
    13561 atgcggctgg agaaaccgtt cagctggcag aaagtctgcc aaatggttgg taccaagttt
    13621 tggttaaagg caatggcttg ggctttgcaa aggttactgg aaatgttttg aaaaattatt
    13681 ttccaaaagg cctcagattc aaatgaaaat gctagtcaaa tatcttattc tatgttatag
    13741 tgaaagtatg gattttttta gtaggatgat tcttgatatc ttgattgcca tcacatgtag
    13801 ttttactact cgatgaaaat caaagagcaa actaggaagc tagccataga tagctcaaaa
    13861 cactggtttg aagagatttt caaagagtac aagaagttta gttattagcg ttcttaccgc
    13921 ttgtaaacta gatttctcat aaaatagaat cttttccttt tagttgtaaa ctagtctggg
    13981 agagtagaga ggtttgagat acctttctag cttttggatt atcatctgag gagagtaatt
    14041 tcccttgcat taaaaagggg aaaaagagac acgaaatgat tataatgggt gacaatgggg
    14101 gaagggatag acaagagatt ttatccacat atgaaaaaag gaggttagga aagagtaata
    14161 tagcctatat tatataaata atcaattgcg cagaaatttg gtaagaattc atgcgtcaac
    14221 tcataaagaa ctacttaaaa aattcacagt attcataatt attttcgagg agaaaaacag
    14281 tgaaaaaaag aaaaaagctt gctctgtctc ttatcgcttt ttggctgacg gcttgtttag
    14341 taggctgtgc tagctggatt gatcgtggag aatccataac ggctgttggc tcaactgcct
    14401 tgcaaccctt ggttgaagta gcggcagatg aatttggcac gatccatgtt ggaaaaacgg
    14461 tcaatgtcca agggggaggt tctggtacag gcttgtccca ggttcagtct ggggcagttg
    14521 atataggaaa ctcagatgta tttgctgagg aaaaagacgg aattgatgct tctgctcttg
    14581 ttgaccacaa ggtcgcggta gctggcttgg ctctgattgt caataaggag gttgatgttg
    14641 ataacctaac gacagagcaa cttcgtcaaa tcttcatagg tgaggtaacc aattggaaag
    14701 aggttggtgg taaggactta cccatctctg ttatcaatcg ggcagccggc tctggttctc
    14761 gtgctacctt tgatactgtc attatggaag gtcagtctgc catgcaaagt caggagcagg
    14821 attcaaatgg agcggtaaaa tcaatcgtat caaaaagtcc aggagctatc tcttatttat
    14881 ctcttaccta tatagatgat tcggtcaaaa gcatgaagtt gaatggctat gacttaagtc
    14941 cagaaaatat aagtagcaat aattggccct tgtggtctta tgagcatatg tatacattgg
    15001 ggcagcccaa tgagttggct gcagaatttc tcaattttgt tctctcggat gagacccaag
    15061 aagggattgt caaaggattg aagtatattc cgattaagga aatgaaggtt gaaaaagatg
    15121 ctgccggaac tgtgacagtg ttggaaggga gacaataatg aatcaagaag aattagctaa
    15181 gaaaatgttg cttccatcaa agaattctcg tctggagaaa ttaggaaaag gtttgacctt
    15241 tgcctgtctt tctttgatag tcatccttgt ggccatgatt ttggttttcg tagcgcaaaa
    15301 aggcttgtcg accttctttg tcaatggtgt gaatatcttt gactttcttt tgggaggaac
    15361 ttggaatcct tctagtaaag aatttggtgc ccttcctatg attttgggtt cctttatcgt
    15421 taccattctc tcagccctta tcgcaacacc ctttgctatt ggtgcagcag tttttatgac
    15481 cgaagtatca ccaaaagggg cgaagatttt gcaaccagct attgaactcc tggttgggat
    15541 tccttcagta gtgtatggat ttattggctt gcaagtcgtc gttccctttg ttcgcagtgt
    15601 ctttggtggg actggttttg ggattttgtc agggatttcc gtcctctttg tcatgatttt
    15661 gccgaccgta acctttatga caacggatag cttgcgtgcg gttcctcgtt attatcgtga
    15721 agccagtttc gctatgggag ccactcgctg gcagactatc tggcgtgtga tcttgaaggc
    15781 ggcccgttct ggtattttca ctgcagtggt ctttgggatg gcgcgtgcct ttggtgaggc
    15841 tttagctatc cagatggttg tcggaaactc agctgttatc ccaacttcct tgaccacacc
    15901 agctgcaact ttaacttcta tattaactat gggaattggg aacactgtca tgggaactgt
    15961 aaataataat gttctctggt cactggcctt ggtactgctc ttgatgagtt tagtttttaa
    16021 cagtgtgatt aaattgatta cgaaagaaag aggaaagaaa aattatgcgc gctaagaaat
    16081 tagataaact tgcaacagct gtcctctata cgattgctag catcattgtg acaatcttgg
    16141 cttccttgat tctctatatc ttggttcggg gcttgcccca tatctcttgg tctttcttga
    16201 ctggaaggtc ttctgctttt caagcaggtg gtgggattgg cattcagctt tacaattcct
    16261 ttttcctatt ggtcattacc ttgattattt ctgtacctct ttctatggga gctgggattt
    16321 acttggctga atatgctaaa aaaggtcctg ttaccaactt tgtgcggact tgtattgaaa
    16381 tcttgtcctc tttaccatca gtggtggtgg gtctctttgg ttacttgatc tttgtagtcc
    16441 agtttgagta tggattttca atcatttcag gtgccttggc cttgacagtc tttaacttgc
    16501 ctcagatgac gcgtaatgta gaggatagtt tgaaacacgt tcaccatacc caacgtgagg
    16561 ctggtctggc tcttgggatt tctcgctggg agacagtggt tcatgttgtt attccagaag
    16621 cgcttccagg tattgtaacg ggtgtcgtct tggcatctgg tcgtatcttt ggcgaagctg
    16681 cagctctgat ctatacagca gggcaatcgg cgccagctct tgactggtct aactggaata
    16741 tcctcagtgt gactagcccc atctctatct tccgtcaagc agaaaccttg gctgtccata
    16801 tctggaaagt caatagtgaa ggcactattc cagatggaac cattgtatca gcaggttctg
    16861 ccgctgtgct cctgatcttt atcctgattt ttaactttgg agctcgtaag ttcggaagct
    16921 atctacacaa gaaattaacc gctgcctaaa ggagaagcca tgtcaacata taactgggat
    16981 gagaagcata tccttacctt tcctgaagaa aaagtagccc tttctactaa ggatgtccat
    17041 gtttactatg gtaaaaatga atccattaag gggattgata tgcaatttga aagaaataaa
    17101 attacagctt tgattggtcc gtcgggatcg gggaaatcta cctacttacg cagtctcaat
    17161 cgcatgaatg ataccattga tattgctaaa gtaactgggc agattctcta tcgtggaatt
    17221 gatgtcaacc gtccagaaat caacgtttat gaaatgcgta aacacattgg aatggttttt
    17281 caacgcccca atccatttgc taagtcaatt taccgtaata ttacctttgc gcatgaacgt
    17341 gctggagtta aggataagca agtcctagat gaaatcgtag aaacctccct tcgtcaggct
    17401 gccctctggg atcaggttaa agacgatctc cacaagtcag ccttgacctt atcaggtggt
    17461 cagcaacaac gtctctgtat cgctcgtgcc atctctgtta agccagatat cctcttaatg
    17521 gatgagccag cttcagcctt ggatccgatt gcgaccatgc aactagaaga gaccatgttt
    17581 gagctcaaga aagactttac catcatcatt gtaacgcata atatgcagca ggctgctcgt
    17641 gcaagtgact atacaggctt cttttacttg ggtgatttga ttgagtatga caagactgca
    17701 actattttcc aaaatgccaa gctacagtcc accaatgact atgtatctgg tcactttggt
    17761 tagaaaggaa accgtatgac agatgcgatt ttacaggtat cagacctgtc cgtttattat
    17821 aataaaaaga aggctttgaa tagtgtttcc ctatctttcc aacctaagga aattacagcc
    17881 ttgattggtc catctggatc agggaagtca accctcctca agtctctcaa ccgcatggga
    17941 gatctcaatc cagaggtgac cacaactgga tccgtggtgt acaatggtca caacatctac
    18001 agtccgcgta cagatacggt tgaattacgt aaggaaatcg gaatggtttt ccaacaacct
    18061 aatcctttcc ctatgactat ctatgagaat gttgtctacg ggcttcgtat caatggaatt
    18121 aaggataagc aggttctgga tgaagccgta gaaaaagcct tgcaaggtgc ctctatctgg
    18181 gatgaggtca aggatcgtct atatgattca gctattggat tgtcaggtgg tcaacagcag
    18241 cgtgtctgcg tggcccgtgt cttggcaact agtcctaaaa tcatcctctt ggatgagcca
    18301 acttcggctt tggatccgat ttcagctggt aaaattgagg aaaccttgta tggtctaaaa
    18361 gacaagtaca ccatgcttct ggtaacccgt tccatgcagc aagcttcacg tatctctgat
    18421 aagacaggat ttttcctaga tggagatttg attgaattta atgataccaa gcagatgttc
    18481 cttgatcccc aacacaagga aacggaagac tatattacag gaaaatttgg ataaggagat
    18541 gaaagatgtt acgatctcaa tttgaagaag atttagagaa attacataac cagttctacg
    18601 ctatgggaca agaagtgctc tcacaaatca atcgtacggt acgtgctttt gtcacgcatg
    18661 accgtgacct ggcaaaagag gtcatcgaag atgatgcaga agtaaatgaa tacgaagtga
    18721 aactggaaaa gaaatcattt gaaatgatcg cactccaaca accagtctct caagatttgc
    18781 gtacagtctt gactgtcctt aaggctgtat cagatgtgga gcgtatgggg gatcacgctg
    18841 tagccattgc ccaggcaacc atccgtatga agggggaaga acgcatccca gctgtagagg
    18901 aagaaattaa aaaaatggga cgtgaagtta aaagcgttgt tgaagcagca cttgatcttt
    18961 atcttaatgg ttctgttgac gacgcatacc gggtggcctc catggatgag caaattaacc
    19021 actattttga aactatccgt gaccttgcga ctgaagagat taagaaaaat ccagaagcca
    19081 ttgttacggg tcgtgattat ttccaagtta tttcctactt ggagcgtatc ggtgactatg
    19141 ctaaaaatat ctgtgaatgg gttgtctact ttgaaacagg taagattgtc gaactataaa
    19201 atagtttaat tctgtataaa aaggagcttg aaatcaactg atggctcctt
//
LOCUS       DAVLZG010000037        19151 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLZG010000037 DAVLZG010000000
VERSION     DAVLZG010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.037"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            96..749
                     /locus_tag="VYO72_001307"
     CDS             96..749
                     /locus_tag="VYO72_001307"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1707675.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            759..1223
                     /locus_tag="VYO72_001308"
     CDS             759..1223
                     /locus_tag="VYO72_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1707676.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1236..2504
                     /locus_tag="VYO72_001309"
     CDS             1236..2504
                     /locus_tag="VYO72_001309"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1707677.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2518..2778
                     /locus_tag="VYO72_001310"
     CDS             2518..2778
                     /locus_tag="VYO72_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707678.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2789..4150
                     /gene="pdrM"
                     /locus_tag="VYO72_001311"
     CDS             2789..4150
                     /gene="pdrM"
                     /locus_tag="VYO72_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1707679.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4304..5272
                     /locus_tag="VYO72_001312"
     CDS             4304..5272
                     /locus_tag="VYO72_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1707680.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5288..6280
                     /locus_tag="VYO72_001313"
     CDS             5288..6280
                     /locus_tag="VYO72_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1707681.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6498..7541
                     /locus_tag="VYO72_001314"
     CDS             6498..7541
                     /locus_tag="VYO72_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1707682.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7605..9290
                     /gene="lpdA"
                     /locus_tag="VYO72_001315"
     CDS             7605..9290
                     /gene="lpdA"
                     /locus_tag="VYO72_001315"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1707683.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELES
                     EEDGYLIAILKGEGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVITDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9354..10343
                     /locus_tag="VYO72_001316"
     CDS             9354..10343
                     /locus_tag="VYO72_001316"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1707684.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10416..11486)
                     /gene="xerS"
                     /locus_tag="VYO72_001317"
     CDS             complement(10416..11486)
                     /gene="xerS"
                     /locus_tag="VYO72_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1707685.1"
                     /translation="MKREILLERINKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAINLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12072..13622)
                     /locus_tag="VYO72_001318"
     CDS             complement(12072..13622)
                     /locus_tag="VYO72_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1707686.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13638..14417)
                     /locus_tag="VYO72_001319"
     CDS             complement(13638..14417)
                     /locus_tag="VYO72_001319"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1707687.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14404..15255)
                     /gene="ylqF"
                     /locus_tag="VYO72_001320"
     CDS             complement(14404..15255)
                     /gene="ylqF"
                     /locus_tag="VYO72_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1707688.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEKAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15336..16844)
                     /locus_tag="VYO72_001321"
     CDS             complement(15336..16844)
                     /locus_tag="VYO72_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1707689.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKRESRKRLDAKFLAIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRTIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFKHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            complement(16920..17153)
                     /locus_tag="VYO72_001322"
     CDS             complement(16920..17153)
                     /locus_tag="VYO72_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1707690.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            complement(17455..17676)
                     /locus_tag="VYO72_001323"
     CDS             complement(17455..17676)
                     /locus_tag="VYO72_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707691.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERSEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(17933..18406)
                     /gene="tnpA"
                     /locus_tag="VYO72_001324"
     CDS             complement(17933..18406)
                     /gene="tnpA"
                     /locus_tag="VYO72_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEV1707692.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            complement(18564..>19151)
                     /locus_tag="VYO72_001325"
     CDS             complement(18564..>19151)
                     /locus_tag="VYO72_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707693.1"
                     /translation="YTIIGVIALLIIGQMTQVIYRVTIDKKYGLLALKLCSGVRPLYY
                     ILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVVLLFWDSLAILLTM
                     FINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPLTYQLTILRNFYFK
                     NSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
BASE COUNT         5735 a         3688 c         3916 g         5812 t
ORIGIN      
        1 tagtcgattt attaaatctt tagataaact gtaaaaagtg gtttccatag ccactttttg
       61 ctataataga ggcagtaaaa atgaaggagt cggctatgga acactcgtct tggcatgctt
      121 tgattaaggc gcaattacct gagggttatt tcgggaaaat caatcagttt atggagcagg
      181 tctattctca ggggattatt tatccaccca aggaaaaggt ttttcaggct ctcttgacaa
      241 cactgcttga agaagttaag gtggtaattc tagggcaaga cccctatcac ggaccaggtc
      301 aagcgcaggg cttgagtttt tctgtacctg actctatccc agctccacca tccttgcaaa
      361 atatcttgaa agaattgtca gatgatatcg gagttaagaa atctcatgat ttgacagctt
      421 gggctgagca aggagtcttg cttcttaatg cttgtttgac tgttcctgct ggacaggcca
      481 atggtcatgc tggtcaaatc tgggagcctt ttactgatgc tgtgattcag gtggtcaatc
      541 atctagatag accagtcgtt tttgtactct ggggagctta tgcacgtaag aagaaggcat
      601 tagttaccaa tcctcatcac ttgattatcg aatcagccca tccaagtcct ttgtcggttt
      661 atagaggatt ttggggttcc aagccctttt ccaaggccaa tgcattctta aaagagacag
      721 gacaagagcc aatcgattgg cttagataag gagaaaatat gcctcagtta gcgacgattt
      781 gctacattga taatgggaaa gaactgctca tgctccatcg taataagaaa cccaatgatg
      841 tccatgaagg gaaatggatt ggtgtgggtg gtaagctaga gagaggagag acgccccagg
      901 aatgcgcggc gcgtgaaatc cttgaagaaa cagggctcaa agccaagcca gttctaaaag
      961 gtgtcatcac ttttcctgaa tttacaccag atttagactg gtacacctat gtttttaagg
     1021 tgacggagtt tgagggcgac ttgattgact gcaatgaggg gacgctagaa tgggttccct
     1081 atgatgaggt tttgagcaag ccgacttggg aaggtgacca cacctttgtt gagtggcttt
     1141 tagaggataa acccttcttt tcagccaagt ttgtttatga tggggataaa ttgttggata
     1201 cccaagttga tttctatgaa taaaggagaa agcagatgct actaatcaaa aatggtcgtg
     1261 taatggatcc caagtctggt ttggatcaag tttgtgatgt cttagttcaa gatgggaaaa
     1321 ttatcaaaat tgcgcctgag atcacggaag aaggagcaga aacgattgat gctactggtc
     1381 ttgtggttgc tcctggtttg gtcgatattc atgtgcattt ccgtgaacct ggtcaaacac
     1441 ataaagaaga cattcatact ggtgccctgg cagccgctgc aggtggtttt actactgtcg
     1501 tcatgatggc taataccagt ccaaccattt cagacgtgga gactttgcaa gcagttctcc
     1561 agtcagctgc caaagagaag attaatgtca agacagttgc gaccattact aaaaacttta
     1621 atggtaaaaa cttgactgac tttaaggcgc tcttagaagc tggtgcggct ggtttctctg
     1681 atgacggtat tccgcttgag agcagtaaga ttgtcaagga agccatggag gaagccaaaa
     1741 aactcaatac ctttatcagc cttcatgagg aagatccagg tttgaacggt gttcttggct
     1801 ttaatgaaaa tattgctaga gaacatttcc atatctgcgg tgctactggg gtggctgagt
     1861 acgctatgat ggcgcgtgat gtcatgattg cctatgcaac taaagcccat gttcacatcc
     1921 agcatttgtc taaggaagaa agtgttaaag tagtggagtt tgctcagggg ttaggtgcag
     1981 aagtcacagc agaagtagcg ccacagcatt tctctaagac agaagcactt tttttaacac
     2041 aaggtagcaa tgctaagatg aatccaccgc ttcgtttgga atcagaccgt cgtgccgtta
     2101 tcgaaggtct caaatcaggt gtcatcacag ttattgcgac tgaccacgcg cctcatcatg
     2161 tagatgaaaa aaatgttgag gatattacca aagcgccatc tggtatgact ggcttagaaa
     2221 catccctgtc tctcagcttg acctatttag tagaagctgg tgagttgagc ttgatggaat
     2281 tacttgaaaa aatgacatac aacccagcca agctttacaa ctttgaagca ggttacttgg
     2341 ctgagaatgg tccagcagat atcactattt ttgatgccaa ggctgaccgc cttgtggact
     2401 cccattttgc ttccaaagca gctaattcac cattcatcgg tgaaacctta aaagggcagg
     2461 ttaaatatac catctgtaag ggacaaatcg tctatcaagc ttgataggag ttagaatatg
     2521 aattattttc gaaaacgtag ggagagacaa gcgaaatcta atagtggaat ttactgtccc
     2581 gcagctaatc gttccaaaat tcaatatgaa actaaagaaa aagctgacca tgcggttcaa
     2641 tatgataacg gaggtttagt tagaagctat tattgtcgta catgtgcgtg ttggcatact
     2701 acttcaaaat ctaataaacc tccgctaagt ttgaaaaact atggtctgaa actctttggt
     2761 ttagataaat cagaatagaa agagaagtat gtataagaca aagtgtttac gagagaagtt
     2821 agtattattt ttaaaaattt tcttcccaat cctgatttac caatttgcca attattctgc
     2881 ctcttttgtt gatactgcaa tgacaggtca atacaacact atggacttgg ctggtgtatc
     2941 tatggcaacc agtatctgga atcctttctt tacatttcta acagggattg tgtcagcctt
     3001 ggtgcctatc attggtcacc atcttggtcg aggaaaaaag gaagaagttg cgtctgattt
     3061 ttaccaattt atttatttgg ccttgggcct atctgtggta ttgctgggga tggtactttt
     3121 cttggcacca acaatcttga atcatattgg gttagaagca gcagtagcgg cagtagcggt
     3181 tcgctatctt tggtttttat ctatcgggat tatccccttg ttgctcttta gcgtcattcg
     3241 ttccttgctg gattcgctgg gcttgaccaa actgtccatg tacctcatgc ttttgttact
     3301 ccctctcaat agcggattta actatctctt gatttacggt gcctttggtg ttccagaact
     3361 gggaggggct ggtgctggtt taggaacatc cttggcctac tgggtcttgc ttgggatttc
     3421 tgttctggtt ttatttaaac aggagaagct caaagcctta caccttgaga aacgaattcc
     3481 acttaatatg gataaaatta aggaaggagt tcgtttaggt ctgcctattg ggggaactgt
     3541 cttcgcggaa gtggctatct tttcagtggt tggcttgatt atggctaagt tttcgtcctt
     3601 gattatagct agtcaccagt cagctatgaa cttttcaagt cttatgtacg cctttcctat
     3661 gagtatctca tcggctatgg ctattgtcgt ttcctatgaa gtgggagcca agcgatttga
     3721 tgatgcgaaa acctatattg gtctaggaag atggactgcc ctcatttttg cggccttcac
     3781 cttaaccttc ctttacattt ttaggggaaa tgtggccagt ctttatggta acgacccaaa
     3841 atttatcgat ttgacagtgc gttttttaac ttatagtctt ttcttccagt tagcagatac
     3901 ctttgcggcg ccgcttcagg gaattttgcg ggggtataag gatacagtta ttccttttta
     3961 ccttggtttg cttggttatt ggggcgtagc aatccctgtg gctacgctat ttgattctct
     4021 aacagatttt ggagcttatt cttactggat cggcttgatt attagtttga ttgtgagtgg
     4081 ggcgctctac cgttggcgtt taactgtgat tatgaagaga tttgaatctt tagcaaaatc
     4141 caaacgctaa aaagtttgtg aaaaaatatt cttgataaga aaatcccttg ttttcacggg
     4201 gttttctttt ttattttgtg aaatttcttt tagaaaaact ttgacagtat ttgccaaaaa
     4261 cggtaaaata gtaaggtaag aagaaagtta gaaaggcaag aagatgtcaa ctttagataa
     4321 aaatcttttg ctagaaatgt tccgtaagat ggaagaaatc cgtcgcatgg acttaaaaat
     4381 tgcacaatta gtaaagaaag ggaaagtgcc aggaatgacg cacttttctg ttggtgaaga
     4441 ggcagctaac gtgggggcta tgttagctct caatccagat gatctgatta cctcaaacca
     4501 ccgtggacac gggcaagcta ttgctaaagg gattgacctc aacggaatga tggctgaaat
     4561 ccttggtaaa tacactggaa cctgtaaagg gaaaggtgga tctatgcata tcgctgacct
     4621 tgatgctggg aaccttggtg ccaatggtat tgtaggtggt ggtatgggga tcgctgtcgg
     4681 tgcagccctc agtcagcaaa tgcaaaatac cggtaaaatc gttgtctgct tctttggaga
     4741 tggtgcgacc aatgaaggtg ttttccacga agcagtgaac atggcttcta tctggaacct
     4801 gccagtcatt ttctattgca ttaacaacgg ttacggtatc tctgcggata tcaagaaaat
     4861 gaccaatata gaacatatcc atcaacgtag cgccgcttat ggaattcctg gaatgttcat
     4921 cgaagatggt aacaatgtca tcgatgtcta tgaaggattt cagaaagctg tggaccatgt
     4981 tcgcagtggc aatggtccag tcttgattga aagtgtaact tatcgctggc tcggtcactc
     5041 atcatctgac cctggtaaat atcgtacgcg tgaagaagtg gaattgtgga aacaaaaaga
     5101 tccaatcgaa aacctccgca attaccttat tgaaaataac attgcaagtg ccgaagaatt
     5161 ggaagaaatc caagcgcaag taaaggaagc agtagaagct tctgttaaat ttgcagagga
     5221 aagcccattc ccaccgcttg aatcagcctt tgaagatatt tacgcagact aaggagaaag
     5281 agataaaatg gaaacaaaaa caatgtcctt ccgtgacacc attatccttg ctatgtctga
     5341 ggaaatgcgt cgcgatgaaa atgtgttctt gatgggagaa gacgtcggtg tcttcggagg
     5401 agacttcggt acttctgttg gaatgcttga agaatttggt ccagaacgcg tccgtgactg
     5461 tccgatttct gaagctgcca tctctggagc agcagcagga gctgccatga caggacttcg
     5521 tccaatcgtc gatatgacct tcatggactt ctctgttatt gccatggaca atatcgtcaa
     5581 ccaagctgct aaaacacgtt acatgtttgg tggtaaaggt caggttccaa tgactgttcg
     5641 ttgtgcagct ggtaacggag ttggctctgc cgcccagcac tcacaatctc tagagtcttg
     5701 gtttactcac attccaggac ttaaggttgt ggcacctgga acacctgcgg acatgaaagg
     5761 cctgcttaag tcttctatcc gtgataaaaa cccagttatt atacttgagt acaagtcaga
     5821 atttaaccaa aaaggggaag tgccagttga tccagactac acaattccac ttggggttgg
     5881 tgaaatcaaa cgccaaggaa cggatgtaac agttgttact tatggaaaaa tgcttcgccg
     5941 tgtggttcaa gctgctgaag aattagcaga agaaggaatt tcagttgaaa ttgttgaccc
     6001 acgtaccctt gttccgcttg ataaggatat catcataaac tcagtgaaga agactggtaa
     6061 ggttgttctg gtcaacgatg cccacaaaac aagtggctat atcggtgaaa tttcagctat
     6121 tatttcagaa tcagaagcat ttgactatct agatgcacca attcgccgtt gtgcaggaga
     6181 agatgtgccg atgccttatg cacaaaacct agaaaatgca atgattccaa cagttgaaag
     6241 tatcaaagat gcaatccgaa aaacttataa caaagaatag agttacataa gataagttat
     6301 gtaaataaaa taaagctgac gagaaacttt gtatctttta ggtgcagagc tcttcgtcat
     6361 taatatctta gattagagca cgggctaaaa gctcggaaaa aagataaatc tccttggctt
     6421 catcgaagcc atcgtcgatt tcctattttt cagtcgcttt tgacgccctt tgtatcataa
     6481 atagaattgg agaggtcatg gctgatgaca agctaagagc gactcctgca gctagaaagt
     6541 tagcggatga tttagggata aacctctacg acgtttctgg ctcaggtgca aacggtcgtg
     6601 tccacaaaga agacgtggaa acttataaag acacaaacgt ggttcgcatt tcgccacttg
     6661 caaaacgaat tgccctcgaa cataacattg cttggcagga aatccaagga accggtcatc
     6721 gtggtaaaat catgaagaag gatgttttgg ccctgcttcc tgaaaatatc gaaaacgata
     6781 gcatcaaatc tcctgctcag attgaaaaag tggaagaagt ccctgataac gtaacaccat
     6841 atggtgaaat cgagcgtatt ccaatgacac caatgcgtaa ggttattgcc caacgcatgg
     6901 ttgaatctta cttgactgcg ccaaccttca ccctcaacta tgaagttgat atgactgaaa
     6961 tgttggctct tcgtaagagg gttcttgagc caatcatgga agcaactggg aagaagacta
     7021 ctgtaacaga ccttctttca cttgcagttg ttaagactct tatgaaacat ccatacatca
     7081 acgcttcatt gacagaagat ggcaagacta ttatcactca caactatgtc aatcttgcca
     7141 tggcagttgg gatggataat ggattgatga cacctgttgt ttacaatgct gagaagatga
     7201 gtctttcaga actggttgta gcctttaagg atgttattgg ccgtaccttg gatggtaaat
     7261 tggctccaag tgagttacaa aattcaacat tcacaatcag taatttggga atgtttggtg
     7321 ttcagtcctt tggtccgatt attaaccaac ccaactcagc tatccttggt gtcagttcga
     7381 caatcgagaa gccagttgtc gtcaatggtg aaattgtgat tcgcccaatc atgagtttag
     7441 gattaactat tgaccaccgt gtcgtagatg gtatggctgg tgctaagttt atgaaggact
     7501 tgaaagagtt gattgaaacc ccaatctcaa tgttgattta agagcaagag tattcatttt
     7561 taagatatag ataaaggaag gaagacatgg ccttagaagt aattatgcca aaagccggcg
     7621 tggatatgac agaaggacaa atcgtccaat ggaataaaaa agtcggagaa tttgtaaaag
     7681 aaggagaaat ccttttggaa atcatgactg ataaagtcag catggaattg gaatccgaag
     7741 aagatgggta cttgattgcc attctcaaag gagagggtga aactgtccct gtaacggaag
     7801 ttatcggtta ccttggtgaa gaaagggaaa acatcccaac agctggagca gcatcgccag
     7861 aagctagccc tgtacctgta gcaagtacct caaacgatga tggtaagagc gatgatgctt
     7921 ttgatatcgt tgtgattggt ggaggtcctg ctggttatgt tgcagccatt aaagctgccc
     7981 aactcggcgg taaggttgcc cttgttgaga aatctgaact tggtggaacc tgcttaaacc
     8041 gtggatgtat tccaaccaag acctaccttc ataacgctga aattattgaa aatatcggtc
     8101 atgctgcaaa tcgtggtatc gtgattgaaa atcctaactt cactgttgat atggaaaaac
     8161 ttttagaaac taaatctaaa gttgttaata ctcttgttgg tggtgttgca ggacttcttc
     8221 gtagctacgg agttactgtt cataaaggaa ttggtacaat cactaaagac aagaacgtct
     8281 tggtaaatgg ttctgaattg cttgaaacca agaaaatcat tcttgctggt ggttcaaaag
     8341 tcagcaagat caacgtccct ggtatggaat cttcacttgt catgactagt gatgacattc
     8401 ttgaaatgaa cgaagtgcca gaaagccttg ttatcatcgg tggtggagtt gtcggtatcg
     8461 aactcggtca ggccttcatg acatttggtt caaaagtgac tgttatcgaa atgatggacc
     8521 gtatagttcc agctatggat gcggaagttt ctaagaacct tcgcttgatc cttgagcgta
     8581 aaggaatgac catcttgact ggtactaaac tgcaagaaat cattgaggaa aatggtcaac
     8641 ttcgtatcaa ggttgaagga aaagacgata tcatcgcaag caaagctctt ctttcaattg
     8701 gtcgtatgcc agaccttgaa ggtattggag aggttgagtt tgaattggat cgtggttgta
     8761 tcaaggtcaa cgaatacatg gaaacttcag ttccaggcat ttatgcacca ggtgacatca
     8821 acggtactaa gatgttggct cacgcagctt tccgcatggg tgaagtttcc gctgaaaatg
     8881 cccttaaagg aaatcatgca gttgccaaat tgaatttgac tcctgcagcc atctacactc
     8941 tccctgaagt agcagcagta ggtttgacag aagaacaagc ccgtgagaaa tacgatgttg
     9001 ccatcggtaa gtttaacttt gctgctaacg gtcgtgctat tgcatctgac gctgctcaag
     9061 gtttcgtaaa agttatcact gataagaaat acggagaaat ccttggtgta cacattattg
     9121 gtcctgcagc cgcagaatta ataaacgaag catcaagcat catcgaaatg gaaatcactg
     9181 ttgaggaaat gctgaagacc atccacgggc acccaactta ctctgaagtg atgtacgaag
     9241 cgtttgcaga tgttctagga atggccatcc attcacctaa gaaaaaataa aacaaagata
     9301 gattagactg gaaggttatt tccagtttct atcatataaa gtaaagggat atcatgaaat
     9361 acattatcaa tcattcaaat gacactgctt ttaatattgc cttggaagaa tacgccttta
     9421 aacacctttt ggatgaggat caaatcttcc tactttggat taacaagcca tctatcattg
     9481 ttggtcgtca ccagaacact atcgaagaaa tcaaccgtga ttatgttcgc gaaaatggta
     9541 ttgaggtagt tcgccgtatt agtggtggtg gagctgttta ccacgattta aataacctca
     9601 actacacgat catctccaaa gaagatgaaa ataaggcatt tgacttcaag agcttctcaa
     9661 ctccggttat caataccctg gctcaacttg gggttaaagc tgagttcaca ggtcgtaatg
     9721 accttgagat tgatggtaag aagttctgtg gcaatgccca agcctatatc aacggccgta
     9781 tcatgcacca cggttgcttg ctctttgacg ttgatttgtc agtcctcgca aatgccctta
     9841 aggtttcaaa agataaattt gaatcaaaag gtgtgaaatc cgtccgtgcc cgtgtaacca
     9901 atattatcaa tgaattacca aaaaaaatca cagtcgaaaa attccgtgat ttactcttgg
     9961 aatacatgaa aaaagagtac ccagagatga ctgaatacgt cttttcagaa gaagaattgg
    10021 ccgaaatcaa tcgcatcaag gatactaagt ttggaacttg ggactggaac tatggtaaat
    10081 cacctgaatt taacgtccgt cgtggaacca aattcactag tggtaaggtt gaagtctttg
    10141 ctaacgttac tgaatcaaaa atccaagaca tcaagattta tggtgacttc tttggtattg
    10201 aagacgttgc tgcagtagaa gatgtccttc gtggggtgaa atacgaacgc gaagatgttc
    10261 ttaaggcgct aaaaaccatt gatatcacac gctacttcgc tggtattagc cgtgaagaaa
    10321 tcgctgaagc ggtagttgga taaatcaaaa agaagttggc caactaacca acttcttttt
    10381 ttgatattta tttacataat ttaaaatacg taaaatcata aactatccag agcattcttt
    10441 tgttcatcat taacaatatg ggtatagagg tcagtgactt gtgtgctggc atgtcctagt
    10501 tggtgactga ctaaaacttg tgatttagta gcatcataga gcctagttgc tagtgtatgg
    10561 cgcagtttat ggggtgttac acgtacttta aaatcctctg agtatttagc aaccattttc
    10621 tcaacgctag aagcatcgat acgattagga acacctctgt agagagttaa aaaaagggct
    10681 gtatctgttt tttccgtttt atagcgttga ttccgaatgg ccagataatt ctctaaataa
    10741 ggtttagcaa aagcagcgac attgactgag tcacgtttgc caccttttcg agtaacatca
    10801 ataaccatca tttttagatt gagatctctt agatctagat taatagcttc agataagcga
    10861 acaccagatg ccaagagaag ggcaataatg gctaaatctc gttctttatt tttgttgaat
    10921 gatgagagag ctcgatttga aagctgttgt gggtgctctt gatcgatata agttagaaaa
    10981 ccttctgttt catcacctag aaagagtttt tgcttgatat tttcagctct ggcagcaagg
    11041 gtttctttct ttttcttggt tgaaactttt ttcattacat tacgatagaa ataaggttcc
    11101 ccctgatcgt tttcaacctc ctcggttaga tacttgtaaa gactagaaag tgctgataag
    11161 gttcgattga tagttgtctg tgaaacacct tgttttgttg tattagcatt cagcaaggga
    11221 cgttcacgta gataaaggat aaaggattcc atgtctttct tagacatatt ttccaaaact
    11281 gataaaggaa tatcggatat tttatcagcg tttgaaatac cagactccaa aacccagctg
    11341 aaaaatcggt catattcctt aaggtattcg tacagggttg taaaactgta gggcacagcc
    11401 agtttagatt ggtagtattc cagaacatac cagggcatga gttgttttag tttgttgatt
    11461 cgttccagta aaatctcacg tttcatgtat tttctccata agtaagtata ctagtagtat
    11521 agcatagact tgtatatttt tcaagaaaat tatagttttt cagaaagatg ttataggagt
    11581 ttttcaaagt gataaaaaga cttagaccta caaacaaaac agaataagga aaataatgaa
    11641 aatctcaccc actaaacttc tgttaatact acataactga agagctatat aaggagctat
    11701 gagatacaaa acacattgta taatagattg aaactagaat agtacatctg gacttctaaa
    11761 acattgctag aaattgattt gattgtcctg tttgttttat cctatttcta tttcatttca
    11821 ctataattac tattgttttc tttttcatga ttttaatctt actgtacaga tttgatacag
    11881 taaactcctt tctagcttta tgctttatca tttctaactt aattaattat agtcttattt
    11941 ttaataaagt tcaattattt atatgtaaaa ttcctcatca gtaaaaaata accgatctca
    12001 tttctgagaa tcggttttct aaataaatca agctgagcat ttacataaca taaattatgt
    12061 aaatgctcat actacaacaa caaatctttg acttttccaa tttcactttt tggaataacc
    12121 aggtgaatca tatcacccag atacattctg gttgagccgt taactgtttg gctcttgcca
    12181 ttatggactt gagttgtgat gaggacgttg tgtggtaagt tgagttcatg aacttgtttc
    12241 ccagcaattt tatcagaaac tggtatttcg ataagtgtaa cttctccttc gctagatact
    12301 tcttctggaa gcattttttc cagcatggct tcatagactg gcgtaccttt gagcaaatcc
    12361 atgataatat aagaaacaag agtgacaaga ccaagtggca tgaggttgcg aatatctcct
    12421 accatctcag ttacgaggat catagcggtt aagggagctt ttgatatggc tccaaaatag
    12481 ccactcattc ctagaatgac aaatataggg aattgctctt gactgacaag tccaagattg
    12541 acacagataa caccaactaa ggcaccaagc aaagaaccaa gagctaaaat ggggaggaaa
    12601 attcctcctg gcagtccact tccatagcta atcatactcc aaataaagcg gatcaaaaag
    12661 taagctaata aaacttggaa actaaaattt tgttcagtta aagaaaggac aagctgattt
    12721 ccgccaccaa tgatttgagg taagaagatt ccgactggta tgataaggat aaaagccaag
    12781 atgggataat aagccctatc caaatggatt ttttgaccaa tcaagtcata aactcttcca
    12841 acgtttaata cagctttctc atagagaaaa cctgaaaatc caaggaaaat tcccatgacg
    12901 agatatatcc aatactggtc tagggtcatg ggaggaatgt tatctggcat atccaatact
    12961 ggtgtcaaac cgaacatgag tagagacaca aagtttgcta cgatgctggc tgctagagtt
    13021 gagacccaga aaaagcgcga aaaatggtga tagacttctt ctacaacaaa gagaagtgct
    13081 gcaataggag cattaaaggc tgcggctaaa cctgctgcag ctccactagc aatcaaggaa
    13141 cgttcctcta ctggactgga tttgagccac ttggcaattc ctttaccacc aactgctcca
    13201 agttgaatgc tgggtccctc tcgacccagc atgagtccac tggcaatagc aagaatacct
    13261 agcacatatt ttttccaaag aatgccccac cagttgaggg acatgaggcc tttcagttcg
    13321 gcttcgactt gaggaattcc tgagccttta atatcttttt ctgaccgtgt tagtttggca
    13381 ctgagccaac agatgagtat ataaaacaaa accagtacaa aaagattgcg cactaagtac
    13441 ccttgatctt gataaactcc ttgtatcagg tggaagccct tttcaattaa gaaacgaaag
    13501 gatccgacga taattccaac gatgaggccg acaatgattc ctcgaccaac ttgggatagt
    13561 atagtgctgg atgcaaaggc gaattctttc ttagaacgga ctatttccga ttgttcctcc
    13621 atggtatttc ctttcaatta actttctttt ttacctaaaa ccagtgattt aacgggttca
    13681 aagctggttc ggtgaattgg ggtaactcct agttttgtga ggccttccag atgtttagct
    13741 gtgccatatc ctgcattagt agcgaaatca tagccaggga actgctgatc gtattccttc
    13801 atcaattcat cacgtgttac cttggctact atagatgctg ctgcgataga gagggagttg
    13861 gcatctcctt tgataatgga ggtttgtgaa atgggcaagt ccagtttcat ggcatcaatc
    13921 aaaaggtgct ctggttgagg gctgagctgg gagattgctt cttgcatggc tagtttggtt
    13981 gcttcataga tattgacttg gtcgatgacc tgattatcta tgataccaat tccaatcgac
    14041 aaggcttggt cttgaacgac ttggaaaatc tccagatgtt tctttttagg aattttcttg
    14101 ctgtcgttga gacctttaat cttacaattt ttaggtaaaa taacggccgc agcgactaca
    14161 ggaccagcaa gaggaccacg accaacctca tcaatacctg caattaaggt caatccttgc
    14221 ttataaagtt ctttttcata agaaagcatg gattccaagc gcaaattttc atctaattca
    14281 gcttggatgg ctcttttacg cttgctgatt tccttttgaa ctcctgagcg attatccttt
    14341 tcaagctcta aaaaaatagg gctttctaac tccttgactg tcacaaggaa ttctttgatt
    14401 tctttaatcg ttgccatcga ggtcttccaa tgtatctaag gtatagttac cgagtttgcc
    14461 atcacggact tccttcacga agagactgta aaaacggtca tagtcatcac ggaaaccgag
    14521 ggcgcgggtc atatccataa taatcacagg cgctttttct tcaattttca tttgtttgaa
    14581 gcgttcagcc agcttttctg gataatgttc tttgaaataa ttgataccaa aaatggtaac
    14641 ctcatccata ggaagcaact ggtctttgat agctccagtc aatgccaact taagtgcaac
    14701 agtttcatcc tcaaacttag gccagagaat ccccggtgta tccaagattt ccaggtcttt
    14761 attggtttta agccattgtt gaccttttgt gacccctggc ttgtttccaa caacagcaat
    14821 ctttttacca gccaaacgat tcatcagagt tgatttacca gcgtttggaa tcccgataat
    14881 catagtacgc aaggtttcaa tctgaatccc acgttctttc tggcgagcaa tcttatcagc
    14941 catgagcttc ttggccgcat ctgttacaac ttttacagtc acttgctctt tggagttgat
    15001 agctagcgtc tggattcctt gtgattcaaa atactgacgc cattccttgg tcattgctgg
    15061 atcagccaag tcggccttgt ttaaaatcaa gagttttggt ttatcaccaa caatcttggt
    15121 caacatagga ttttgactag atagaggcaa gcgtgcatct actaaaatcg tcacaaaatc
    15181 aacaaatttt aaattctcct gcacctgtcg acgagcttta gacatgtgac caggaaacca
    15241 ttgaatagta gccattgagt tttttccttt cgtagcaagg gtttagcacc cctcatttat
    15301 tttactatcg tctaaacacc aagcgaacac caaaactacc acgaaatgga aaaacctttg
    15361 atttgattcc cgcttaattt cacaatcttt atatcaaact gtgggtgata tttgacaata
    15421 tcttttttga tttttaacag taaatttgaa acaatatgtt tgggtgagta acgtgaacca
    15481 aggtgtaata agtctttaaa ttcatcaaca cttaactcta ctttattgtt atcatcacaa
    15541 gtttcaatga attgttcaat cattctcgaa tatttacagg tgtaactctt caattcttta
    15601 aagtgaaaat tgtgcttttc tacaaattga tttaaagcag ttacagtatt ttcttgtgaa
    15661 cgactgatgt tatgggtgta gcccatcgtg gtttcaaaat tcgcatgacc aactctagtc
    15721 ataatatcct ttacagctat gtgcatttca ttactttgaa gataactaat gtgcatatgt
    15781 ttgaaagaat gaggggtcac atgcttgacc catttaaaac cataatcctt ctgacaattt
    15841 tttaacaact tctcctcaac cctcttcaaa acttgacgaa atgagtgaga agttatcgga
    15901 gaaccatact cagtttgaaa tacactatca cactttttga aagcaggact aggattttgt
    15961 tccatatagg cttcaaattc ctgatttctt tttatagttc tctggattgc ttcactcgct
    16021 gctattggga gggctacctc tctatcagca ttgacggtct tagtcgtatc aaaataaaat
    16081 tcatcaactt ttaaatcatg atattggaga gccttatcaa tatgtaaaat ccccttatca
    16141 aaatcaacat ctgatggtaa aaaagcagcc tctccaatcc gaatccctgt cagtaataat
    16201 acaatagcaa ggtcataata gctagcattt ctacactgcc ctaaaacatc aaaaaaggct
    16261 tgcaattcat gaattgcaag aaatttagca tcaagccttt ttcttgattc tctctttttc
    16321 tccagaggca catctatttt aacagcggtc attggagagt acttaatgac attgtatagc
    16381 acaccgtgat taaatatctt gttacacgta ctttttatat gtgtcattgt tgaaggtgaa
    16441 gcgtcgtatt tatccagata tttattaaga caatttttca tcagtagtgg tgtaattcga
    16501 tcgagtaaaa attcatcacc gataatttta ccaagccgtt ctatcaccaa ctcttccctt
    16561 tttattgtct ggggcttgac agatacgcac caagtttgaa accaactctc ttttaactct
    16621 ccaaaagttg taatcatttc aggattgtac tgactttcaa gggaagaggt cagtttttct
    16681 attttatcca ttacctctct ttcagcttgc tttcgtgctc tactagtatt tctagtatag
    16741 ctgacagtta ctgttctcca cttatcagta agtggatctt tatatttttc aaccacttga
    16801 tacaagggtt gtccttttga atttgtttta gttacataat acataattta attcctcgaa
    16861 aagaaataaa tcattgttgt atagaataaa taactactct atattatacc atgacttcct
    16921 tattttgtcc gcttttgttt ccatctcaaa aagcattcga atccctcaag atttataaac
    16981 accagcttat gtgtaggatt gatgacgtat aaagaaaatc tcttattttc tctcatttct
    17041 ttgatccatc tgttaagagt gtagagattc aaaccttccc atcgtttcag tatgcttttc
    17101 ttatccgccc actcagctac cgaattttca acagatacgt attttatctc catattatca
    17161 tcctttcgaa taatttcttc tccctccatg gcatgactga tggggtcatc ataagaatct
    17221 cacttactgc tcttttacga cggcagcctg aacgttcaga agtatcattg tatatcattt
    17281 gcatcatggc agatagagta tcgctctatt ttattggtga ttgtccccgc tcctatcttg
    17341 gcgaatcaag caaaactgct ccacaaatga ggaaagtacc attttaggct attcagttgt
    17401 caaagggcaa ataaaaaatc tcactcattt tcaaactcta tgaaattgag gagattattt
    17461 tctaaagcga attttatcag gaaaatcagt taatcccaat aaatagtctg tactgacgtc
    17521 atagaaatct gagagtttaa ccaatacatc agccgtcaac gcatgctcac tccgttcaat
    17581 tttggcataa gctgaatttg taaacgaaag tattgtagct atttgctttt gggtcagatc
    17641 atgatcctcc ctcaaatctc tcaaacgtct gtacatctag ctttctccta agaaaaagta
    17701 tagaccatat attgtaacta tttaggatat tgtccaaatc ggacaacagg aattttacca
    17761 tcctttatat agacttttat ttttatgtat caagtttttt aaatcaaaac caccagtgtg
    17821 aactggtggt ttgttctgcg gctataagcc gcttctaccg gccagggcca aaggcccacc
    17881 gaaatagctt cctcgcgcac cactttcccg agcaggtgct aaagcacctt agttacttcc
    17941 tcttatttat ttcgccagta aacggatcta ctgactcgaa taacgtgagc tggtctgcta
    18001 ctctgtcttc ttgtaattga ttctgaatat attcagctat cactttctga ttacggccta
    18061 ccgtatctac ataatagcct ctacaccaaa acttgcgatt gccatatttg tattttaaat
    18121 tcgcatgctt atcaaaaatc atcaaactgc tcttgccctt taaatagccc ataaaggacg
    18181 aaacactaag tttcggagga atactgataa gcatgtgaat atggtctgaa caagcattcg
    18241 cttcatggat tattacaccc ttacgctcac ataagtcacg tatgattctt ccgatactag
    18301 ctttgtatct gccataaatg atttgacgac gatatttggg tgcaaaaaca atatgatatt
    18361 tacaattcca tgtggtatgt gataaacttt gattatcctc tctcatgagg tacctcctgt
    18421 atgatatgtt gtagtggcgg agaaaccact tctatcttat cattttagga ggttcttttt
    18481 gttaccacgc taaaagctct atggaaccac tagcatagct agtggttttc gggagacaac
    18541 aaaaaagttg gatgacccaa cttttatctt tctatcagta tcaattttat ctttggtata
    18601 ataaaagata cagatataag gacaagtaat gatgttaaca ataagaaaac taattccaaa
    18661 gttgttgaat ttttaaaata aaagtttctc aaaatagtta attgataagt taagggattt
    18721 aactgaccaa tccatctcac aatactagga gcagaatcta ttaagtagaa aacaggagct
    18781 gtaaaaccaa gcggtgttag tacaaaacgt attacaatat cacgtcttct gtaatcattg
    18841 ataaacattg taagtaaaat tgcaagggag tcccaaaata ataaaacaac aatagataac
    18901 aaaactgtat aaaaaaatct atccattgcg atatttatct caaacgctaa cgtaattata
    18961 tatataataa tttcttgaac tatcaaccct aatatagaat agatactcat ccctaaaata
    19021 taatataaag gacgaactcc actgcataac ttaagagcaa gtagcccata ttttttatct
    19081 attgtcaccc tataaataac ttgagtcatc tgcccgatta tcaataaagc tataacacca
    19141 atgattgtat a
//
LOCUS       DAVLZG010000038        19082 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLZG010000038 DAVLZG010000000
VERSION     DAVLZG010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.038"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(1..432)
                     /locus_tag="VYO72_001326"
                     /pseudo
     CDS             complement(1..432)
                     /locus_tag="VYO72_001326"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(470..802)
                     /locus_tag="VYO72_001327"
     CDS             complement(470..802)
                     /locus_tag="VYO72_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707694.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(815..1588)
                     /locus_tag="VYO72_001328"
     CDS             complement(815..1588)
                     /locus_tag="VYO72_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1707695.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2035..2790)
                     /locus_tag="VYO72_001329"
                     /pseudo
     CDS             complement(2035..2790)
                     /locus_tag="VYO72_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2928..4550)
                     /gene="groL"
                     /locus_tag="VYO72_001330"
     CDS             complement(2928..4550)
                     /gene="groL"
                     /locus_tag="VYO72_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1707696.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4566..4850)
                     /gene="groES"
                     /locus_tag="VYO72_001331"
     CDS             complement(4566..4850)
                     /gene="groES"
                     /locus_tag="VYO72_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1707697.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5120..5515)
                     /locus_tag="VYO72_001332"
     CDS             complement(5120..5515)
                     /locus_tag="VYO72_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1707698.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5593..6354)
                     /locus_tag="VYO72_001333"
     CDS             complement(5593..6354)
                     /locus_tag="VYO72_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1707699.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6387..7013)
                     /locus_tag="VYO72_001334"
     CDS             complement(6387..7013)
                     /locus_tag="VYO72_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1707700.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7029..7346)
                     /locus_tag="VYO72_001335"
     CDS             complement(7029..7346)
                     /locus_tag="VYO72_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1707701.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(7343..7642)
                     /locus_tag="VYO72_001336"
     CDS             complement(7343..7642)
                     /locus_tag="VYO72_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1707702.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7927..8118)
                     /locus_tag="VYO72_001337"
     CDS             complement(7927..8118)
                     /locus_tag="VYO72_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1707703.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            complement(8279..8953)
                     /locus_tag="VYO72_001338"
     CDS             complement(8279..8953)
                     /locus_tag="VYO72_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707704.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(8959..9405)
                     /locus_tag="VYO72_001339"
     CDS             complement(8959..9405)
                     /locus_tag="VYO72_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707705.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9519..10022)
                     /locus_tag="VYO72_001340"
     CDS             complement(9519..10022)
                     /locus_tag="VYO72_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1707706.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFFLF"
     gene            complement(10019..10381)
                     /locus_tag="VYO72_001341"
     CDS             complement(10019..10381)
                     /locus_tag="VYO72_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1707707.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGEAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10507..12306)
                     /locus_tag="VYO72_001342"
                     /pseudo
     CDS             complement(10507..12306)
                     /locus_tag="VYO72_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(12345..12794)
                     /locus_tag="VYO72_001343"
                     /pseudo
     CDS             complement(12345..12794)
                     /locus_tag="VYO72_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(12918..13634)
                     /locus_tag="VYO72_001344"
     CDS             complement(12918..13634)
                     /locus_tag="VYO72_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1707708.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14515..15930)
                     /gene="ply"
                     /locus_tag="VYO72_001345"
     CDS             complement(14515..15930)
                     /gene="ply"
                     /locus_tag="VYO72_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1707709.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(15941..16273)
                     /locus_tag="VYO72_001346"
     CDS             complement(15941..16273)
                     /locus_tag="VYO72_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707710.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16344..16952)
                     /locus_tag="VYO72_001347"
     CDS             complement(16344..16952)
                     /locus_tag="VYO72_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707711.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(16965..17423)
                     /locus_tag="VYO72_001348"
     CDS             complement(16965..17423)
                     /locus_tag="VYO72_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1707712.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17548..17947
                     /locus_tag="VYO72_001349"
                     /pseudo
     CDS             17548..17947
                     /locus_tag="VYO72_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18711..18971)
                     /locus_tag="VYO72_001350"
     CDS             complement(18711..18971)
                     /locus_tag="VYO72_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707713.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAIISSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         5695 a         4224 c         3312 g         5851 t
ORIGIN      
        1 ttcaataaac tcaaaatatt ttatgacatt gtccatttgt ttaattccag attctttaga
       61 ttctgtcagg tatattttat atccttctac aaatttgaat gtagattttt caaaaacttt
      121 tgtgtcatct tttaataatt tttgtaattt catttcaaag tagtctgcat atattagatg
      181 tgaattttca aggcaacaga accaaaaatt taaacaagct gacacaacta aatgtctatt
      241 cttgccgatt ttttcgtaat aatgtgtacg ctctagtatt tcttttccga ccatgtaaat
      301 ataatctatt tcaaaaagat gatataaatt accaatcagc gttatctcat aggacttcca
      361 tcgttccttc tggaataaat agtcatatac taaatttaga tcatctctac taactacatg
      421 attacaatct agctgatttc ataatccctg aaccataatt gtatttattt tatgagtttt
      481 tcccactctt ctcaaaaagt ttttgttgct tattttttat tacctccaat cctttaatat
      541 tcaaactata aaaatttgga gataaattaa ccaaaaaatc atcacgctcc gatcttttat
      601 aatgttctaa gtgattacaa aaattctcta tcgaaacatt gatatttgat aataattcaa
      661 aaaatgttga aagagaaatt tcattttctc ccctttcaaa tctagaaagt tgagattttg
      721 atatagaatc agctgcagca tactctaaag aatatccgtt taattttcta aaatatcgaa
      781 aagcttctcc gtaatttttc acactttcat tcccttaact ttcttttcga gcgataaaca
      841 taccatattc tttaggaatg atcaacatac cattattaaa ctcactttcc aatcttttac
      901 gtattatttc ctcttctagt gaacctattt ctgaaattcc tttaaacgat tggatgtatt
      961 taactaggtc atctatacta gttacctgta actcatcatc atagagtaat gtatcgacag
     1021 agttaaaata cctactcagg taccttttac cattttgtaa agtaaacgtt ctattttcta
     1081 aatcttgatt aacctcatct ttaaataaat ttgccaaata atttacaact ccattttcac
     1141 caaatgtagc acagtaaaaa attcctccgg tttttaagac cctattcacc tcagagagag
     1201 ctttaggaat atcattcaca tgatgtagaa gcatattagc aataacaata tcaaaagttt
     1261 cattctcaaa agaaatcttt tgaatatcca ttatctcata attgacattg tttctatttc
     1321 caatcactga cttcgttgat tttaccatat ctttagaaaa atctgtaaca atcaactgct
     1381 tcattttatc tatagaatca ctattacttt tccacaattc tcctgtacca catcccaatt
     1441 ctagaacctt tacttcatca gtgatttggt agttagaaaa tatccaatta ttaaatccca
     1501 atttattttt tgaatacttc ttatgcaatt ctactcgaat atcaagatta tcatgacttt
     1561 tatattgttc aattacttta tcaatcattt taaatgacct ccactctata atttggcatt
     1621 atatcacaag aataaagata gtgttaaata agttgtataa atgcaaaaaa ggaatattcc
     1681 gttatagcag agttgtaaca catttctata aagaaattta ttcctacgac tcagtttggc
     1741 atgcttaact tcctaactca aaaacaaagc atcgattaat ttatccgttc ttcttttgaa
     1801 acagatttga actgataatt gctcgtttta atttaagaag ctcttttgag caaaacttca
     1861 tttttttaag agtccaacaa tttctgtcta tcgcttttct actagcaaaa aaaactacct
     1921 tgaggcaagt tttcatttat atatctaatt tcgtaatagt atagtaaaat gaaataagga
     1981 cagtcaaatc gatttctaac aatgttttag aagtaaaggt gtactattct agtttcaatc
     2041 tactataaat ttgatatgag aatagtcttt ctcaacatcc ttacccaaca agaatgctgt
     2101 agcgtccttc ttaacttgaa ccaggtcaat attctgggct tgggctgcat agacgcagcc
     2161 acaataacat tgacgataga tatcatactc ctcacacatc tctactgaac gtttgtagcc
     2221 ttgatttttc ttgaaatcgt tgggaagata gtgggtcgtg taaatttttt gcacatcgat
     2281 tccgatgctg ttgatggttt gagaattctt atgaggactg atggtcaagg ctgaaccaaa
     2341 gtagtcaaag cccaagtcca tagccacttg cgctgtttta tccagtcggt agtcaaaaca
     2401 aaccttgcaa cggtcgccac cttcgggctc ctcctctagt cccctaacta gttttcggta
     2461 ttaattgggt tcgtagggag cttctaggta ctgaaccgta tttcctgtcc gctcattaaa
     2521 atcactaaca aatttcttga tgacatagac ccgcttatgg tattctacct tgggatggat
     2581 attagaattg gcaaaataga tggtcacatc tgcatacttg gtcaaatatt ctagtgtata
     2641 ggtactacaa ggggcacagc aaacatgcac gagaatggtt ggccgctgct catttttctc
     2701 ccatgcttgt accattttct gcatgacacg gtcataatta atcttctgat tggggggcat
     2761 cttgcacaga atttcttcta catcgatcat gttcttctcc tttttctagt cttattttat
     2821 catataagtt aggagagctc aaatcaattt agaagtgaat attataaaaa gaagggttag
     2881 tcattccctc cttttgtgtt ttttataagt tgttttctat agaaagctta catcatcccg
     2941 cccatcatgc ttggatccat tgctggagct ggggctactg gttctggttt attggctacg
     3001 actgcttctg ttgtcaaaat caagctggct acagatgctg cattttgtag ggctgaacga
     3061 ctcactttaa ctggatcaat gataccttga tcaatcatgt taacccactc gccagttgct
     3121 gcgttgaatc ctataccaag ctcagcattt ttcaaacgat cgataacgat agatccttca
     3181 aatcctgcat tgtgagcaat ttgacgaaca ggttcttcca aagcacggag aacaatatta
     3241 cgtcctgttg cttcatctcc tgtcaattcc aaggtagcaa cagctggaat cacattggca
     3301 agagctgttc caccacctgc aacaatacct tcttcaacag ctgcacgagt agcgttgagg
     3361 gcatcttcaa tgcggagttt catttctttc aactcagttt cagttgcggc tccgacctta
     3421 ataaccgcta caccacctga caatttggcc aagcgttctt gcaatttttc acggtcaaat
     3481 tcagaagttg tagtttcgat ttgagacttg ataaccgcaa cacggtgaga aatcgcttca
     3541 ggatttcctg caccttctac aataaccgtg ctatctttgt ccacggtcac tctcgctgct
     3601 tgaccaagag cttcaattgt cgcatctttc aactcaagac caaggtcttc tgtgataact
     3661 gttccgcctg ttaagatggc gatatcttca agcatagctt tgcgacggtc accaaaacca
     3721 ggtgccttga ctgctactac gttgaaggtt ccacgaatct tgttcaaaac aagagttgga
     3781 agagcctcgc catccacatc atccgcaata atcaagagtg gacgattgct ttggagaatg
     3841 ctttccaaaa gtggcaagat ttcttggata ttggaaattt tcttgtctgt aatcaaaatg
     3901 tacggatttt caaggtcagc caccattttt tcgctatctg tcaccatgta ctgtgaaagg
     3961 taaccacggt caaactgcat tccttctacg acttcaagct ctgtttccat accacgtgac
     4021 tcttcgatgg tgatgacacc gtctttgcca actttttcca ttgcttcaga gatgtactca
     4081 ccaacttttt cagaacgaga agatacggct gcaacttgag cgatagcttc tttattggca
     4141 acagggatgg cgttgttttt caaagcttca actgctgcgg caactgctgt ttcaatccca
     4201 cgacgaatac cgattggatt tgcacctgct gtgacgtttt tgattccttc acggacgata
     4261 gcttgggtca agactgttgc agtcgtagtt ccgtcacctg cgatatcatt ggttttagaa
     4321 gctacttctg atactaactt agcacccata ttttcaaaat ggtcttccaa ttcgatttct
     4381 ttggcaatgg tcacaccgtc attggtaatc aagggtgaac cgaatgactt ttcaagaacg
     4441 acattgcgac cttttggtcc caaggttact ttaacagtgt ctgcaaggat atcgacacca
     4501 cgaaccatgg ctgaacgggc atctgatgaa aatttaattt cttttgacat acttactttc
     4561 tccttctatt cctcaatgat tgccaagatg ttagcttcgc ctacgatgat gtacttttca
     4621 tcgccatctt tgacatcaag acctgcgtgg gcttcaacta agacacgatc tccagtttta
     4681 acacttggag caaccaagtc accgttcaag gtacgaacac cttgtccagt agccacaact
     4741 tgagctgttt tggttttttc ttgggctgag cctgcaagga caaagccccc aacggtttgt
     4801 tctttttctt ctatttttaa gaccacacgg tcccctaatg gtttcaacat ctgatttcct
     4861 ccataatgag atagatatta ttagcactct ttgaacttga gtgctaattc ataattctat
     4921 tgtatcactt ggtcagaaat agtcaagaaa aaagtctgac tttctcaaga taaaaagcct
     4981 gagaccaact cagacttttt aatgtttata ctcaatgaaa atcaaagagc aaactaggaa
     5041 gctagccgca ggctgctcaa agcattgctt tgatgttgtg gataaagcta acgtggtttg
     5101 aagagatttt cgaagagtat taaaatggca attcttcctc ttccaagacc aaatctgcca
     5161 aatcttggcc tgcattattt tcacgcatgg cacgttgagc acgactttct aagagttgga
     5221 atcctgtcac aaggacttcg gttacatagt tcatctgacc atttttctca aagcgacggg
     5281 tacgcaattc tccatcaacg gaaatgagac tacctttggt tgcgtagctt gccaaagttt
     5341 ctgctagcct gccccatagg accatattga caaaatcagc ttcacgttca ccgttttggt
     5401 ctttgtaacg acggttgaca gcgatagttg ctcgcgctac cgacttgtca ttgttggttt
     5461 tgtgcaattc tggtgtagac gttaaacgcc caatcaagat aactttatta tacatatttt
     5521 cttcctccta cttatctatt cgtaggaaat caaaaaaagt tacagaaatt tgtaactttt
     5581 cgaggaaatt tcttattttt tatgaatcat gaaacctgtc gcctgttgat tggccataat
     5641 ggtcatatct gtaatctgaa cacggcgagg ctgactggtc acatagacta ctgtgtctgc
     5701 aatatcctga gcttgcaagg cttctattcc ttggtaaacg gacgcagccc gctctttatc
     5761 accatgaaaa cgaacagttg agaaatctgt ttcgacaatc ccaggctgaa tggttgtcac
     5821 cttgatatcc gttgcgatgg tatcaattcg cagtccatcc gaaaaggtct taaccgcagc
     5881 cttggtagct gagtaaacag cggcaccagc ataggcgtag attcctgcgg ttgaccccat
     5941 attgataata tgaccttgat tgacttttat cattgctggc aagaaacagc gagtaaccgc
     6001 catcagacct ttaacattgg tatccaacat ggtcaacata tccaactcct catagtcttg
     6061 atagggagcc aagtcaagag ccagtccggc gttgttgacc aagatatcaa tcctccctat
     6121 cgtttctaga atatcagagc aaacagtctt caccatgacc atatccgtca catctagtgg
     6181 aaaagtccag acggtttgat ttggaaagct tactgcaaac tccgacttga ggatttctaa
     6241 tctgtctatc cgtcgtcctg ttagaacgac atcctcaccc tgctccagat aagcacgcgc
     6301 aatcgcttca ccgattcctg aggttgctcc cgtaatcact acattttttg ccatcttatt
     6361 tccttctatc agatgctgac aagttcctag gcagtccagt gtttcgctgg gtcgaacggt
     6421 gttccgacaa cttggtcttc tgataattca agcaccccac gtttttgcgg agcatttggc
     6481 aaatgcaatt cacgaggact acacatcatc ccaaaactct tttcaccacg aagttcgcct
     6541 gggaaaatga aattcccttt tggcatcatg gcaccaggaa gagccacaat ggttttcaac
     6601 ccaacacgcg cattaggtgc tcctgcaacg atttgcacta tcttgtcact tgcgactgca
     6661 acttggcaga tgttgaggtg gtcactgtct ggatgagcta ccatctcgac aatttcacca
     6721 acaacaaact taggttcctt atcattaaca atttcttctg taaaaccttc cgcctgtaat
     6781 tcttggttca aacgagcgac ttgctcatct gataaaaaga cttgaccgcg ctctgcaatt
     6841 tcaaacaagc tcgaaacctc aaaaatgttc caagctactg tttccccatt ttctttgagg
     6901 aaaacacggg ctaccttgcc tttgcgttcc acattcagtt tggcatctcc gctatttttc
     6961 acgatgacca taaggacatc accgacatgt tctttgttat acgtaaaaat cattgtttcc
     7021 tttttctcct atttcaatcc tgctaaaaaa tcgttaattt gctccttact tttacggtcg
     7081 cgattgacaa aacgaccgat ttccttgtcc ttttctagaa caacaaggct aggaattccg
     7141 taaacatccc agagtttggc caaatccata tactgatctc ggtccattcg aataaaggtg
     7201 aactctggat tggtctcttc aatctctggt aaggcaggat aaatataacg acaatcgcca
     7261 caccagtctg ccacaaaaag gaagaccttc ttgcccgctt tttccactaa agatgctaat
     7321 tcttctaaac ttgctggctg tatcataaga cttcctcctc atagactagg tcttcatttt
     7381 catagacaaa ggtataatga cggccatcct caaaaatgac gccaccaagc aagctctcta
     7441 gactgctttc atagacttga acatagaggg tcgcaatttc ccccatgtct gaaaaatggt
     7501 ctcgcacaat ctctgtcaac tcttcctgag tcttcatgag cttacggtca tctgcaactt
     7561 ttttcgtagc aagagcaagg cttccgatac ctagcagagc caagcctgcc atccacattt
     7621 ttttagcttt cataccattc attttaacac aaaaaaggct tcaggacaaa tgaggaagca
     7681 gcagaaaagc aagtaaaaag cctcttcctt taaggaaaag gacttcttat actaagagca
     7741 aactagaaag ctagccgcag gctgctcaaa acacggtttt gaggttgtag ataaggcgac
     7801 gttgacgtgg tttgaagaga ttttcaaaga gtattattct tattgccagg cacctaagtt
     7861 gccaacgtag taaccatcag gtgtgtaggt attgcgaagc atcttacctg atgaagccag
     7921 ataatactac ttgccattgt ctttgaccca atcattcgca atcatggcac cagaagaact
     7981 tacataatac cattctccct tgtcataaac ccaagtactg actttcatgg ttcctgagca
     8041 attaaaggca aaaaaactgt ccaatatcat tcgtttttta aaagcatttg acactacatc
     8101 atctacgctg taggacatag atgcatcaaa cgtaaaagcc aaaatatcga aaaatataca
     8161 acttttaaag gcagcatttc attttttaaa gtctaacaac catagaactg aaatcagagc
     8221 aaggcatcaa tttcctactc ttagtacgtc tattttgatg gttgaagtga agattttttt
     8281 atttaacgta gacaatttcc aacttcccaa aagccacatc tccacggata atcaaggttt
     8341 tgctggttgg ggctacagga gcgtcagcct tagctgcacc aaaggaggtt tctactttca
     8401 aatctacacg ccagtgttgt ggaacataga cggttgcatt tccgaaggcc acttcaatat
     8461 ttaaagttgc aaaatcacct agcatctctg cattatcata gtagatttta gcatccccaa
     8521 aagcgacttc cacttggtca tctacgagat cttgatcttg cttatagaag gtcccgctac
     8581 caaaagcgac ttccttatcc gtgacgactg tttttttccc attgtaccac catttttttt
     8641 cattccagaa cttacttgaa tgcgtcagat aaccaacacc aagtaccacc aagatgctag
     8701 cccaaataag agaatgattg gtaactggta acaagtcata agcgtaattt gcaatgatga
     8761 tcgccagtaa acctgtaaaa actgccgaag tgagatgacg tctaaggatg gactcaatgg
     8821 acttataagc aaaaaaaaca atacctagta aaggccatat tttaccatcc aaagaaggaa
     8881 ttccaaaatt cccttgcagc aagatccaag ctgctaaaac caataaaaca ataccaaatg
     8941 ctttcttttt catgtttttt acctcatgtt tcttagattt tcttttagga gggattggta
     9001 atgccgtgag acatgaacct ccttgtgcgt ctgataaaag gaaatggtgc ccgttcctga
     9061 aaaggacttg tccactgagt aaatctgacg gatgtttgcg atcgttgact tggaaactcg
     9121 attaaaatag cgaggcaaga tagactccaa ctcatagagc ttgaggcgaa cctcataagc
     9181 ttccttctgg ttatgagcgt agatcttgct cccttctgtt tcaaagaaga gaatttctga
     9241 caggtctaga taatattcac ctgtcccctt gtaaaaagtc aacctcggag cctttgactc
     9301 ttgcaagagc cgttgcaagt ctgcaatttc atctgtcaaa gtgggggtct tgatgacaat
     9361 ttcagtctcc tctaaattgc cgtcaatctc aattcgtaac ttcatcacat ctcctttctg
     9421 actctactat atcaaagcta agttaggaat acaagggcaa aaaagcaagt ggtcaatttg
     9481 aagcagtaag tggttgcaag accaacttaa cttacaggtc aaaatagaaa gaaaagcaca
     9541 ccccacgcaa gaccacaaat ataaccaact actacatcct tgggataatg tacaccacct
     9601 aagactctca cgagaccgag gagggctgac aagaccaaca agataaagcc cacagttaga
     9661 ctagcatgta agcaagtcat ggagataatg gttgctgaaa agacatgacg actgggcata
     9721 gactgaccag gactatctct gtcaagcaag ggtttaatat cccattcctc ataaggccta
     9781 ggggcattga ttttcttacg aagaagggat aaaatcacaa aacctgtagc agggataaac
     9841 acataaaccc caacttgctg accaagtcct agttgcaggt aagtggtgac tagcaagatc
     9901 agatagacca ggggcatggc gactgtcatc aaacgattga aactgcgtaa taggaataaa
     9961 agaattggac gactagttag tctggagctg atatttcgat accattcttg ataatttttc
    10021 atttatgctt ctcatacttt tctagaactt gttgagatgt tttccccttg gcaagccaat
    10081 ccactagctt gtccaagcga cgtatttcct gcatcagagg atcatcaatt tcctcaatac
    10141 ggacaccgca aatcttccct gtaattgcaa ttcgttcagg gacataatat ggtgcttgtc
    10201 gaaaaaaatc tccgtaagta acatccctat ccagacaagc aagaacgtca ctcacttcat
    10261 accctgtcaa ccaactggtc acttggtgaa ctgactctgc ctctccaccc tttcgctcaa
    10321 cttttgcaat caaggctaaa tagacagcag caaatttcat attgtataat ttctgactca
    10381 tacttctctc tttctatgtg tactagtata aataagaaaa agaaggccgt caagccttct
    10441 tttgatttat tcttctgctt catcttctgt aaattgacta ttgtacaagt cagcgtagaa
    10501 gccaccttac accatcagtt cctcatagtt gccttgctcg atgatatttc catctttcat
    10561 gaccaagatc aagtctgcat ttcggatggt tgacaagcgg tgggcaatga caaaggatgt
    10621 gcgtccttcc atcaaacggt ccatggcttt ttggatcaat tcctctgtcc gtgtgtcaac
    10681 agaagaagtc gcctcatcca aaatcaaaag cggtgcatcc ttaagaaggg cacgagcaat
    10741 agtcaatagt tgtttttgtc ctacagacaa ggtcacggtg tcatccaaga tggtatcata
    10801 gccatctggc aaggtcataa taaagtggtg aattcccaca gccttactag cttccatcat
    10861 tcgttcatca ctaatcccta tttgattata gatgagattg tctcgaatag ttccttcaaa
    10921 gagccaggta tcctgcaaga ccattgaaaa ggcatcatgc acttctgaac gcgtcatagc
    10981 cttggtatcc acaccatcaa tgcgaatact tcccttatca atctcataga atttcatcaa
    11041 aagattgaca atggttgtct taccagcccc agtcggccca acaatggcaa ccctttgacc
    11101 agcatgagct gtcgcagaga agtcatagtc ttgaacattg acaccgtcca ccagaatttc
    11161 tcctgctgac acgtcgtaga aacgtggaat cagattgacc agagttgatt taccagaacc
    11221 tattgaccca ataaaggcca ctgtttgacc agtttctgct ttaaagctaa catgttcaat
    11281 aactgcctcc gaatttgccg catagcggaa ggtcacatcc ttaaactcga cctgaccttt
    11341 gaagttttca tcagtcagct gcacttgagc agggttttgg atagaagaat gcaaatctaa
    11401 aacttgatta atccgcttag cagagaccat agttcgggga agaacgatga agagtgctcc
    11461 catgagaagg aagtccatga caacctacat ggcataagac atgaaaacaa tcatgtcact
    11521 aaagagaggc agacgcgcta tcggagcagc gtcgttaatc acataggccc caatccagta
    11581 aatcgccaca ctcaaaccac ttgaaatccc catcatgata ggattcaaaa tagccataag
    11641 acggttgaca aacaaatttt aacgggtcaa ttcatcattt actgctgcaa atttttcatt
    11701 ttgataatcc tctgcattgt aggcacgaac gacacgaata cctgttaaac tctcacgagt
    11761 gatactgttc agtttatctg tcagcccctg aatcaaggac tgttttggaa aggctagcgt
    11821 catcaaaacg gtcgtcatca ggacgttgac aatcactgcc acaagtacgg cccagagcca
    11881 gtattctgaa tgacctaaaa tcttcccaat agcccagata gccataattg gaccacacgt
    11941 taccacttgc aagtccatag taatcaacat ttgaacttga gtaatgtcat tggtagtacg
    12001 catcaagagg ctaggaattg aaaatttctt aatctctgtc tgcgagtaat ccaaaactcg
    12061 gttaaaaata tcacttctca gcctactagt ataagaagcc gccactcggg atgcaaaaaa
    12121 tccaactgca actacggaca agaaggcaag aaagggcatt cccatcatca tgcttgccgg
    12181 ctgccacaac tcatctaaat tagtttcttg actacctagc aaatccgtaa ttttcgagat
    12241 ataggtcggc acttccaact ctagatagac cgaaaagcaa gtaaagagaa tggctagtaa
    12301 aatcatcccc cattcttttc tactaattct tttggttaat ttctttattc tctcctccta
    12361 ttcccttgat attttgcctg tagttgaccg agaactttct caaaaatcag taattcatct
    12421 tcatcaatgt cttccatcaa ctgcttgtct atgcgttcaa aaaaagcctt aacctgttgc
    12481 atctgagaac gtgctttgtc cgtcagacga acaaacttag cccgcttatc aacaggactc
    12541 gcctccaatt ccaccaaacc attttgcact atacgcttaa ccagattact agcaacagac
    12601 ttggtaatat tgagttcctg ctcgatatct ttaatcaaga ccaagtcttg atttttctag
    12661 cgattatcca aaaaacgcac aacctgacct tgcggcccac ccataaattc aatgccgcaa
    12721 cgtttggctt ccttttgcac catcaggtaa atttgatgac caaaacgctt aaagactaac
    12781 atcggtttat ccataatctc ccccttctaa ataaaaatag ttctctggag aataattaaa
    12841 tttctatgag aactattttc ttgattaaaa aaatcccaag tgattttctc acttaggatc
    12901 atgttctata ggttaaatta aaacccatct acgttcgtat aaatcttttg gacgtcttcg
    12961 tcgtcttcaa gaacgctgta aagtttttca aaggtttcaa ggtcttcgcc tgacaattcc
    13021 acttctgact gaggaatcat ttccaattca gtcacttgga attcttcaat accagactca
    13081 cggagagcaa cgatagcctt gtgaaggtca gttggcgctg tgtaaactgt gattgtacct
    13141 tcttgtgctt ctacgtcatc cacatccaca tccgcttcga gcaattgctc aaagactgcg
    13201 tccgcatctt cacctccaaa tacaataaca cctttgttgt caaaaaggta agaaacagaa
    13261 cctgaagcgc ccatgtttcc gccgttttta ccaaaggctg cacggacatt ggctgctgta
    13321 cggttaacgt tagaagtcaa agtatccaca attagcatag agccatttgg cccaaaacct
    13381 tcgtaacgtc cttctgtaaa ggtttcgtct gtgtttcctt tggctttatc aatcgcttta
    13441 tcgataatgt gttttggcac ttgggcttgt ttagcacggt cgataacgaa tttcaaagct
    13501 gagtttgatt ctggatctgg atcacctttt ttagctgcta catagatttc tacaccaaat
    13561 tttgcatata ctttagagtt agctccatct ttagccgttt tcttggctac gatattggcc
    13621 catttacgtc ccattaggaa tctccttttt tcacatttta atctttctta ttataacaca
    13681 agtttttttg attttcacta gaggaaatgg attttattag caaatcaagc taggatagca
    13741 ctttacctgc taagatggtc ttgcctttct atctttatca acagacactc atccacattc
    13801 aaaaaacaaa ctagaccatt atctgcaaat agaaagtttc agccaagttt gacaaagtca
    13861 gctcaaatta ctgtttgaag tttgtagata taagcgacaa aaacaatcat actgcacctt
    13921 ttgttgacag tctactccag acatatcata gttcaagtaa atactttgaa attcaacagt
    13981 tcttataggc gctattgtat tctaagaaat caatagaaga gtttctaagc aaacctctaa
    14041 tactcaataa aaatcaaaaa gcaaactaga aagctagccg caggttgctc aaaacactgt
    14101 tttgaggttg cggataggac tgacctggtt tgaagagatt ttcgaagagt ataatttacg
    14161 tgttcccaag atggagaaat tagactagta cactggcact tctaaaccat tgctagcaat
    14221 tgatttgttc atatttaatt tcattttttc cataaatggg tattagatat aaacagcaaa
    14281 atatttccga tacgtgtcat tcttgaattt ccaatcatct aaaacaagta aaggataatc
    14341 aatcccctgt atatcaagga attggctacc ctttttactt ttttacacat tctgtttgat
    14401 agattcattt taacatcacg agcatactcc aatggaaatc gctaggcaag agataaactt
    14461 tcagatattc gcagagagct catcgcctct ttttgtcgca aacattcttc tctcctaatc
    14521 attttctacc ttatcctcta cctgaggata gagagttgtt ccccaaatag aaatcgtccg
    14581 cttacgcact agtggcaaat cggttttttc ataaaccgta cgccaccatt cccaggcaag
    14641 cccggtacac tctctaattt tgacagagag attacgaaca ttccctttta aaggaatact
    14701 agtggtaaag tgagccgtca aatcctgccc atttctgtcc caagccttag gagtcaagac
    14761 ttccttacct tgatgatcat aggataattc atcccaagta atataatatt gggcaacata
    14821 ggcaccacta tgatccagca gtaaatctcc gtttctgtaa gctgtaacct tagtctcaac
    14881 atagtctgta ctattttgaa aggtcgcaac tacattgtca cgtaaaaaag aagttgtata
    14941 ggaaatcggc aagcctggat gatctgctgt aaagcgactg ccttcttgaa tcaagtcctc
    15001 taccatatcc accttgcctg ttacaactcg ggcacccgaa cttgggtcgc cccctaaaat
    15061 aaccgccttc acttctgtat tgtccaaaat ctgcttccac tctgtctgag gagctacctt
    15121 gactcctttt atcaaagctt caaaagcagc ctctacttca tcactcttac tcgtggtttc
    15181 caacttgaga tagacttggc gcccataagc aacactcgaa atatagacca aaggacgctc
    15241 tgcagaaatt cctctctgtt ttaaatcctc taccgttaca gtatcttgaa acacatctcc
    15301 tggattttta acagcatcta cgctgactgt ataataaatc tgcttaaaat taacaatctg
    15361 aatctgcttt tcgcctgaat ggacagagtt aaaatcaata tcaagagaat tccctgtctt
    15421 ttcaaagtca gaaccaaact tgaccttgag ttgttccatg ctgtgagccg tgattttttc
    15481 atactgcatt ctagctggga cattattgac ctgaccataa tcttgatgcc acttagccaa
    15541 caaatcgttt accgctccgc gaacacttga attgctgggg tcttccactt ggagaaagct
    15601 atcgctactt gccaaaccag gcaaatcaat actataagtc atcggagcac gatcgaccgc
    15661 aagaagagtg ggattattct ctaacaaggt ctcatccact acgagaagtg ctccaggata
    15721 gaggcgactg tcgttggtag ctgttacaga aatatcactt gtatttgtcg acaagctccg
    15781 cttctttctt tcgataacaa caaactcatc gggtagctga ttaccctctt tgatgaaacg
    15841 attttcaata ctttctccct gatgggtcaa gagtttcttt ttatcgtaat tcatagctag
    15901 tataaagtca tttactgctt tatttgccat cttatacctc ctaataagtt cctggattga
    15961 gttgcataaa ctcagacttg ttcagcgaaa tcagccgtgg ttggactaag tgatccaaaa
    16021 tttcctcgta caattcttct gagacattgc gtcgccgtct ggctagataa gaagtcggaa
    16081 taaccgtatt atccaacata aataccttat ctaagtcaat caaggttggt cttgtaaaag
    16141 gattacgagc tagatccggc tcttctatca taaagttctt gaccaaacgt ctggtcaaga
    16201 gagctggttt gaaggtctga tttttaacca actctttgtt tttagtcatg ctgttgtcaa
    16261 tacagatata catatgattc ttcacagcca aatcgctact aatagtcgga aaaggcaaat
    16321 aaagagctac aacatctcct ctcttaatca agcaagagca cccccttttc tcctaatgta
    16381 acatagacag gattgaccaa gtcttctgat tgactcagaa tttccaaagt ttgagtttgg
    16441 cgcgctgtca atttagtagc atcttgtctc ttcaatacaa aatgcttgtc gccaataacc
    16501 ttgacaatat aatccttctc caaagctgac tggtaaatcc acatcagatg ttgtctgtcc
    16561 tgagaactca agagagaagg attttcaagc ctcccgatag tctgataaaa atcaaaaaca
    16621 ggagctaact cctgccaatc tgattggcta gttgtcaagg ctagaaaaag ggctttgcga
    16681 gctgatactt cttggttagc cttgagagtt actttcccct ccaagttttt tagaaatcgg
    16741 gaaactccag aaagcaaatt tttctctaac tgcgagaaat aaaaaccttt cgttcccaga
    16801 cataagtctt tcatgtcgct ttctctagca aataagagct caaacatttg atagtaaaag
    16861 aaaaatatct ggcactgggt cgcgctcatc ttttccttat cggcttcttt ttttaaccag
    16921 agcaagggcg acaggtagct ggattgagac atttcctcta cctcctactc ttttttaact
    16981 ggagcatctg cactagctgc cacttctttt gactggatac tttcccactg gttaatctcc
    17041 tctgagataa gaccttcgca tgtcttgaca aatagggcaa aagccttggt ctttcctgca
    17101 tatttctccg tttggcattg atagaggaat ttttctttct ccaggagttg cgcagttttt
    17161 tggtaagaaa tccaattttc ctttgcatta tacaaattga taatcccctc acacagcaag
    17221 ccgagactgg ataaggcaac cgaaatcaaa cggtagcgat cacctggcat aggaatagca
    17281 caaaagacag ctatgaggaa acctgccacg atttctgtta tttttaatac cttatagcgc
    17341 ctacgatgtt gaacgctttt ctttaaaaaa tgagctatct gtacgtctaa tcgctctgtc
    17401 aggtacattt cttctggcgt catattcgta actcctttca tttactttga taaccatagt
    17461 ataacatatt tgaatatcaa agtatagtaa aaactggact ataacttatt agactccctg
    17521 cgaaacaaaa tatggtatag tagttctatg aattatgaag caagtaaaca attaactgat
    17581 acacgattta agcgtcttgt tggtgttcag cgtaccactt ttgaagagat gttagctgta
    17641 ttaaaaacag cttatcaaaa aagtcggaca agctggtaaa atcttggctg acagtaatta
    17701 tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca gcaaactcaa
    17761 gccactaaca gttgaagata aagtctataa ccatgcgcta tctaaggaga gaagcaaggt
    17821 tgagaacatc tttgccaaag taaaaacgtt taaaatgttt tcaacaacct gtcgaaatca
    17881 tcgtaaacgc ttcggattac gaatgaattt gagtgctggt attatcaatc atgaactagg
    17941 attctagttt tgcaggaagt ctattatata tatgcacaga catatgaaat ctttttgata
    18001 cagccttctt tttacataga gagacagcag ttatgatata tttatccatt cacaacatct
    18061 tctgtaccaa tactacaata ttggtacatt ttgattacac aatcgtttca aaaaatatga
    18121 tggaagcctg agtattttat agtaattccc ttcctatcaa ctagatcaac cagttgagtg
    18181 ttgaatgttg aaacacccta gcctcagcaa aggactatga tcagcatttc ctagccaata
    18241 ggacgctcca aatcacctat tctaagtcca tcactagctt ggtcagtaag atacagactg
    18301 caaggcaaga ctgacgtggt tgatgagatt ttggaagagt attacaatca tagattcacc
    18361 agtagacttg accgcagatt taactatagt agattgaaac tagaatagta cacttctgct
    18421 tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg ttctcgtttc
    18481 attttactat actaaaaaac cacctgaaac aaatcaagtg actagaggat aaaaacaaag
    18541 actgggcaaa aagttttgaa aagcaaaaaa cgcataatat caggtcttga aaaaccttga
    18601 tactatacgt ttgattgtgg gaagattgac ttcattttct cctgaaattg aagttttttc
    18661 tagtttccag atatagacga attcaatata gccatctcgc tacaattatt ttaaccatcg
    18721 agaaaatttt tcagaatttc aaaaatttca ttttgatcca atgaaatgtc atcattttga
    18781 agaatagttg acttcacagg ctctaattct atcacaaagc ggtgcatgtc tgcttttacc
    18841 gcactacttg atattatagc cgataacttt tcatctccta gcaaggaagc tgtcaaacgg
    18901 gtaatgtcat tcaaatgctt tttaatggac ttacttaaat cttgagcacc tgtagcagag
    18961 cgctctctca tatccagcca agctttagcc ttaaaaataa ttaatactca atgaaaatca
    19021 aagagcaaac taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg
    19081 ga
//
LOCUS       DAVLZG010000039        19054 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLZG010000039 DAVLZG010000000
VERSION     DAVLZG010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.039"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..4289)
                     /locus_tag="VYO72_001351"
     CDS             complement(<1..4289)
                     /locus_tag="VYO72_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1707714.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGKWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKV"
     gene            4582..6214
                     /locus_tag="VYO72_001352"
                     /pseudo
     CDS             4582..6214
                     /locus_tag="VYO72_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            complement(6459..6698)
                     /locus_tag="VYO72_001353"
     CDS             complement(6459..6698)
                     /locus_tag="VYO72_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1707715.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(6718..6990)
                     /gene="rpsP"
                     /locus_tag="VYO72_001354"
     CDS             complement(6718..6990)
                     /gene="rpsP"
                     /locus_tag="VYO72_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1707716.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            7160..7369
                     /locus_tag="VYO72_001355"
     CDS             7160..7369
                     /locus_tag="VYO72_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707717.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            7851..8063
                     /locus_tag="VYO72_001356"
     CDS             7851..8063
                     /locus_tag="VYO72_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707718.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            8147..8950
                     /locus_tag="VYO72_001357"
     CDS             8147..8950
                     /locus_tag="VYO72_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1707719.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGNGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(9006..10547)
                     /locus_tag="VYO72_001358"
     CDS             complement(9006..10547)
                     /locus_tag="VYO72_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1707720.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(10549..11031)
                     /locus_tag="VYO72_001359"
     CDS             complement(10549..11031)
                     /locus_tag="VYO72_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1707721.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(11031..12116)
                     /gene="rlmN"
                     /locus_tag="VYO72_001360"
     CDS             complement(11031..12116)
                     /gene="rlmN"
                     /locus_tag="VYO72_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1707722.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMTIGARHITVSTLGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(12137..12667)
                     /locus_tag="VYO72_001361"
     CDS             complement(12137..12667)
                     /locus_tag="VYO72_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1707723.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(12823..13428)
                     /locus_tag="VYO72_001362"
     CDS             complement(12823..13428)
                     /locus_tag="VYO72_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1707724.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(13601..14638)
                     /locus_tag="VYO72_001363"
     CDS             complement(13601..14638)
                     /locus_tag="VYO72_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1707725.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(14672..15607)
                     /locus_tag="VYO72_001364"
     CDS             complement(14672..15607)
                     /locus_tag="VYO72_001364"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1707726.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(16160..17350)
                     /locus_tag="VYO72_001365"
     CDS             complement(16160..17350)
                     /locus_tag="VYO72_001365"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1707727.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(17565..18908)
                     /locus_tag="VYO72_001366"
     CDS             complement(17565..18908)
                     /locus_tag="VYO72_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1707728.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
BASE COUNT         5490 a         4169 c         3514 g         5881 t
ORIGIN      
        1 actttcttat ctttttcaat tgggattttc acaatagaag cgtaagagag atcaacatct
       61 tgaccttttt catccaaacc ttctatttca aagacatgag catcttctcc agcaaagtat
      121 ttcttctctt cagcacttgc ttgaacacgc tctactttca aacccttgat gacagtcttc
      181 tctttatttg agaagtgtac ttcaacacct gttttactat cagaaaagac tgctggcttg
      241 tcttctttca ataaagcaac cagatctttt agactctgtt tcgctgttgc aagctcttct
      301 ggactcaaat ctactttttc aaccaaggcc ttgtttttct caagaagcgg agctagggca
      361 gaacctgaag gatggtttgg tttggcagcc aagagttctt gaacctcacc tgttaagcga
      421 tcaagttctg tcttttcttc cttaaatttc tcttgaccat tcagagcttt atgagcttct
      481 gtcaatttat taagtcggtc attgacttga tcttgggtgc tagtttcatg gtctttcaac
      541 acttgttcgg ccgcttcaat tgctttcaag aaagcttctt ttacttctgg tgaagcaaag
      601 ttatagacca ccttgttctt agcagcttca acttctgcta atttctgttt gaggtactca
      661 tcgttcaatg ctgcttttgg agataccaaa acatcaaagt tgacttcatg accttggtaa
      721 cgaagcgtca aggtttgacg accagtcttt tgagcatcgt aaccagaaat ttcaactccc
      781 tcatcagtaa aggaatgttc ttccatggtg tcattgctat aagccactgc aaagcgtcct
      841 tcagacaagt ctaagctatc accaactagg taatcttttt tcggttcctg acttacttca
      901 attcccaaaa tagttttcgg acttgcttcg tcttggccag tgacagtcac tgacaaatta
      961 gcatttactg gttgtcccaa atattggaga gtaagattct gttctccctt atgatgcgta
     1021 tcaaaacctg atactgatac acctgcgtga gttaggcgaa tgagttcgtc ctcagttcct
     1081 ccttcatact gaactcgaag aacaccacct ctaaggtcca aatcctcccc ttcggcgtag
     1141 cttgttttct taggtcctgt ttctaggctg actgacttga ttcttctgtc atcttttgga
     1201 acggaaactg ctaggacatt actaatttcc ttgcctggca actgggtacg ataataaaga
     1261 agaccagatt gatttgtcaa atccaatggt gcacttgcta ggtctcctcc aacttcgctc
     1321 ttcaaggttg cgagtggagt ttgagaattt ggattatcat aaacggtaat agttgctcca
     1381 gccggtacat ctgcaaagcc aacttgtacc ttgttattgc ctagagaacg ggctgcagcc
     1441 ttggccatcg gaatattgac actctcagta tcaagctttt catacatttt ccagttatag
     1501 atacgaatag ccttccatgg agttccattg tcagaagtga caacattcaa gcgccagtct
     1561 tgagcagtga ttggtttatc aagagtgata tctgtcacgt gtgctttgtt gccacggact
     1621 tccttagcta gcttccactt accatctgca tctttataat aaaggtcaaa gtctttggtg
     1681 ttcatcaagc catcgttaac agactcacca ccagcccctg catgatccat gacccatcta
     1741 acaacggtac gtggcttggt caaacgaata tccacactac cactcaactg agctgaagac
     1801 catttatctg acaagctagt aatggtaccg ttcaacatac cttcaatacc ttctccacct
     1861 tctgtatctg ggaaggtact tccgataaca gtagcccctg gaacgatgtt ttctgctaga
     1921 ggtcttggaa gacttgtgtc ttggacagtc atcccccact caaaggttgt ggttgcagct
     1981 tctgaacgaa ctccattttt accgactgct acaaccttca gttcttgagt tgtaccctga
     2041 gcacttgctg agcggctaac ttttggtaga taaatagttg tagaagatga gccagttagt
     2101 aatttccagc tgtctccatc tttttcataa acttcataga aatctgcatc cttgttgcct
     2161 ttaaattgca caactgcttc cgcttcttgg gcatttttaa gagattgttt cactacagaa
     2221 aagcttgtcg gcgattgtgg ctcttggtga ttgtccgaga tagttaattg tcctaggtta
     2281 aactgataat cttttacagc accttcatgc tcgaaaaata gtttgactgc atagatggtt
     2341 ttacccgcta gtgagctaag atcaaattct tcatttgtcc agttgtcaga aagggttagc
     2401 tctttccatg catctgcatc atcgaatttg tagtctggag ttgtagagaa tgccatataa
     2461 actttagaac cttttcctcc cttgtgggca acacgaagtt tggtcttctc agttacttct
     2521 aacttagtag aataaagtct cacatcctga tctgtcttac cggctacatc accagagaat
     2581 ttaagggaat ttccgccatt ataggcatct gtaaaatcat attctgcacg aagtttttcc
     2641 cctgttgaag tctgccacca gcgccatgtt ggaagaacac ctgatactga acgataattc
     2701 cactcagaat ccttagaaac cttaccatct acgaaccatt ttttaccatg acctgtatta
     2761 aaagaagtag taaaagtatt acctaccgct ggcgtacggt ccgcaactag gttagcaata
     2821 ccataccaat ctttgtcacc tggtttttga ccagtagggt ctccttgata acctgtaaag
     2881 aagatatctt catttttatg ataatcttca ccagtttttc ctaaacttgt aatggtatct
     2941 ggggcaaata aaccaagaga aaggcgcaat ttcccatttt cgtctaaaat gtcattccac
     3001 ttaacctttg tcttgtagga accaccctgt tgcaattcca aacctgcaaa tacatcataa
     3061 ggattacgac caatccagtt ggcagttgca atagtgtaat catttttagc cttatcccag
     3121 ttaaagttag caaagaagtt atctgccgga accttatctc cttctggttg catgaattgg
     3181 tagttgtatt ctcccaaacc atcttgatgg taacgtccat agttataggt catggcatca
     3241 taccaagaat acttgattgg atggtttacc ttagcagcat attccttgct atagagcata
     3301 aactggcgca tcttttctcc aagaggttta accaaatctc cagttgtttc ttggttgatg
     3361 aaatagccat catagccata atacttggcc atgtctacca atttacgggc aattgggaag
     3421 ctaccatctg cgtcttgctt caaagcttca gcaaatcttt cttgatctgc aatactatta
     3481 gaccagttga agaagagtgt accgtataca ggaaccccgt tacggtgacc tgcatcaata
     3541 acgtcaggag ttggtacgag accttcccag aagaccattg aatctagata ttgccaatag
     3601 tcaaaagcat aggccttgaa ctcttctcca ccaacagaag catggtcttt tgctttagaa
     3661 ttggtgtttg ataaggcttg aacttttgct tccttgctag ctttttcatt gactaaatga
     3721 cctgtccgac gtgaagcgag gacaacagat ccgcggttaa tagcatcatc ttcacgagca
     3781 cctggttccc attttaacaa ttcttcccaa gaattaaatt tgatttcctt tggttttaat
     3841 gttttttctg tatttttagg gacatctggc tggacttctt tttcagtctt attagcttct
     3901 gctgctggct tagactcatc cccttggtta gttgcttcgg gctttgcttc tgtttccttg
     3961 tcagacttag gttttgcttc tgcagatggt gtttctgcaa ccacctcacc tgctttttcc
     4021 tctggtttag ctgcgctagc tgcttctgcc ttttctagct tgttttctct agcatgttcc
     4081 ccttcattct gcttatcagc ttcattggtc gaatgctcac tctctcctga aacaagctct
     4141 gtattagctc cgctattttc aggaactgca gtttcttcag ccaaggctgg accagcaaat
     4201 aaaacagcac caatcatcag cgagcaggct cctactgata acttacgaat actgtaacga
     4261 caacgtcttt caaaaaatgg attcttcatt ttctcctcct aaaagattga ttttgttgtt
     4321 ttaaagaaag cgctttatat tctgtagttt tttatcaaac tctagaacca tgataatcac
     4381 atttttatcc taaaacattt ttagacaaaa aacaataact gtttgcacaa atctaaaata
     4441 aggttaaaaa ctcttaaaaa taatacactt atcaattata attttctttt acaaacttga
     4501 cattaacact tgttagattt acttttatcc tttaaaatag aataggagat attccgcgat
     4561 tatttttcgg aggaaaaaga aatgtccatt aattggcagg aaattttatt tcacttttta
     4621 ggtggtctgg ggctattctt atatagcatc aagaccatgg gagacggttt gcaacaagct
     4681 gctggagatc gccttcgttt ttacattgac aaatatacta gtaatccttt ctttggagtt
     4741 ctggttggta ttgggatgac tgctctaatt cagtctagtt ctggtgtaac agttattaca
     4801 gtcgggcctg gtcagtgccg gtctcttaac cttacgtcag gctatcggga ttgtcatggg
     4861 tgctaatatt gggacaactg tcacatcctt tctcatcggt tttaaattag gtaactatgc
     4921 cctacctatg ctctttatcg gtgccgtctg tctctttttt acgaaaaatc ggacagtcaa
     4981 taatatcgga cgcatcctct ttggtgtcgg tggtatcttt tttgccctca atctcatgag
     5041 cggcgcaatg gctccactca aggatttaca ggtctttaag gactatatga ttgagctaag
     5101 taagaatcct gttttgggtg tctttgtcgg taccggcttg accttgctaa ttcaagcttc
     5161 ttcggctacc attgggattt tacaaaacct ctacgccggc aatctaattg acctacaggg
     5221 agctttgcca gttctatttg gtgacaatat cgggacaacc attacagcca tcattgcctc
     5281 tttaggggct aatattgcag ctaaacgggt agcaggagct catgttgcct tcaacgttat
     5341 cggaacagtc gtctgcgtta tttttctagt tccttttact gtcctgattc attggtttga
     5401 agctacgcta aatctagcac cggaaatgac catcgccttt gctcacggaa cctttaatat
     5461 taccaacacc attgtccaat ttccatttat cggagctctg gcttactttg taaccaagat
     5521 tattcctgga gaggacgagg ttgtcaaata cgaaccctta tatcttgatg aacatttcat
     5581 caaacaagcc ccatctatcg ctctaggaaa tgctaaaaaa gagctcttgc acttaggaaa
     5641 ctacgctgct aaagcctttg acctttccta taagtacatc attgacttgg atgaaaaagt
     5701 tgctgaaaaa gggcataaaa ccgaagaagc aattaacacc atcgatgagc aattaacacg
     5761 ttatctcatt gccctttcaa gcgaagctct cagccaaaaa gaaagtgaag tgctcaccaa
     5821 tatccttgat tcctcccgtg atttggaacg gattggagac cacacggagg ctctactcaa
     5881 tctgactgac tatcttcaac ggaaaaatgt tgaattttct gatgccgcct tgaaagaatt
     5941 agaggaagtt taccgccaaa ctagtgactt tatcaaagat gctctggata gtgtggaaaa
     6001 caatgatatt gaaaaagcac gcagtcttgt agaacgtcat gaagcaatca ataagataga
     6061 acgtgttctc agaaaaaccc acatcaaacg cctcaacaaa ggcgaatgtt caacacaagc
     6121 tggggtcaac tttatcgaca tcatctcaca ctacactcgt gtatcagacc acgctatgaa
     6181 ccttgctgaa aaggtttttg cagaacaaat ctaagaacca agaagctatc catcataatt
     6241 ggatggcttc ttactttttc ctaagcaaga ctaggctgaa tgaaactgaa agagtattct
     6301 gcagatatat agtatattga aactagaata gtacacctct atttctaaaa cattgttaga
     6361 aatcgatttg actgtcctga tcgatttgtc ctgttattat ttcattttac tatatcttct
     6421 attccacaca aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt
     6481 cttacttttt tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg
     6541 cgacccttac gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc
     6601 aaaaattctg gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt
     6661 ttcacaatcg caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta
     6721 ttttgagaat ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg
     6781 tactgtgtct gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa
     6841 agttacttgg ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc
     6901 gtcacgtggt gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc
     6961 catacgagtc aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat
     7021 ttcggtgaaa tagctgagct atttagcaca tgttctatta tagcagattt ctggcaggtg
     7081 tcaagaaaaa aacttgacag actataaatt tcttaaagca tttagaaatt tgttagaata
     7141 ggaaataaat gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga
     7201 acaccaagtc aaacccttca tatcgcctga acgagatttg gatacttggc ttctaagtcc
     7261 caaacccgtt cccaagcgaa atatggactt attagcagat gattcactag caggagatat
     7321 cattttacta tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact
     7381 cccattcgaa tatgattcaa aattcgctta gaatcaatgt tttcccactt tttcaaaaaa
     7441 taaattttca tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta
     7501 aaaaacaccc catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt
     7561 agcgtttaga gaactggcta gctttacgag ctttcttaag atctggttcc ctaaatactt
     7621 tgagtacact tatggcattg atgccccaaa acatctaaaa actctggtag aaaaagggta
     7681 tgctcttgtc gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa
     7741 tatcctgaag aagaagaagg gagttactgg actttctaaa atgaaatctt gcgacctgga
     7801 tcaagccctt catgagcatt tttcagaaga agaattagct ggtcactttc atgtccttct
     7861 atggactttt ttacaatggc attgctatca cacccaatac ctatctaagc gcctggttcg
     7921 taaactttat tgcagctctt cctctaaatt tcctaattgt tgaaccaatt gcccgtttta
     7981 tactaagttc ttttcagaaa ccatttactg gggaagaagt tgaagatttt caagatgatg
     8041 atgaaatccc aactattatc taagccagtt ctgtaaacta ctaatatttg aaatccactt
     8101 ccttttaggg tacaatggtt ataaatgaat ttttgagagg atcagaatga aaaaactagc
     8161 aacccttctt ttactgtcta ctgtagccct agctgggtgt agcagcgtcc aacgcagtct
     8221 gcgtggtgat gattatgttg attccagtct tgctgctgaa gaaagttcca aagtagctgc
     8281 ccaatctgcc aaggagttaa acgatgcttt aacaaacgaa aacgccaatt tcccacaact
     8341 atctaaggaa gttgctgaag atgaagccga agtgattctc cacacaagcc aaggtgatat
     8401 tcgcattaaa ctcttcccta aactcgctcc tctagcggtt gaaaatttcc tcactcacgc
     8461 caaagaaggc tactataacg gtattacctt ccaccgtgtc atcgatggct ttatggtcca
     8521 aactggagat ccaaaaggga acggtacagg tggtcagtcc atctggcatg acaaggataa
     8581 gactaaagac aaaggaactg gtttcaagaa cgagattact ccttatttgt ataacatccg
     8641 tggtgctctt gctatggcta atactggtca accaaacacc aatggcagcc agttcttcat
     8701 caaccaaaac tctacagata cctcttctaa actccctaca agcaagtatc cacagaaaat
     8761 tatcgaagcc tacaaagaag gtggaaaccc tagtctagat ggcaaacacc cagtctttgg
     8821 tcaagtgatt gacggtatgg atgttgtgga taagattgct aaggccgaaa aagatgaaaa
     8881 agacaagcca actactgcta tcacaatcga cagcatcgaa gtggtgaaag actacgattt
     8941 taaatcttaa aaaccaaaaa aatacagtat ccacattcgg tactgtattt cttttactct
     9001 cattcttaag ttaaattatt aaaatcccat atttggtcta tccagccttc ataaaagtct
     9061 ggctcgtggc agaccataag gatagatccc ctatattctt tgagagcgcg tttgagctca
     9121 tcctttgcat ccacatccaa atggttggtc ggctcgtcca gcactaaaac gttgttttca
     9181 cgattcatca agagacagaa acgaaccttg gcttgctctc cccctgataa tacttgaatc
     9241 tggctttcaa tatgtttggt tgtcaaacca caacgggcaa gggctgcacg gacttctgct
     9301 tgattaaggg caggaaaggc attccagaca gcttcaagag gagtttggcg attaccgcct
     9361 tctacttcct gctcaaaata accaagttct aaataatctc cacgctccac ttccccagcg
     9421 attggcgaga taatgcctaa gagactcttc aagagagttg tttttccaat accattagca
     9481 ccaataatcg caaccttttg attgcgttcg aaggtaagat ttaaaggctt agtaagagga
     9541 cggtcgtaac caatttgcaa gttcttggct tggaagataa agcgccctgg tgtacgagct
     9601 ggtttgaaat caaaggatgg ttttggtttc tcactttgga gttcgataat atccatctta
     9661 tccaatttct tttgacgaga catagccata ttacgagttg caacacgggc tttattacga
     9721 gccacaaagt ccttgaggtc tgcaatctct ttctgctggc gttcgtaggc tgcctctagc
     9781 tgagatttct tcatagcata aacttcttgg aactggtagt agtcaccaga gtaacgcgtc
     9841 agctgttgat tttccacatg atagacaata ttaataacgt cattgaggaa tggaatatcg
     9901 tgcgaaatga gaacaaaggc attctcatag ttttggagat agcgcttgag ccaatcaata
     9961 tgctcagcat ccaagtagtt ggtcggctcg tccaacagca agatatcagg cttttcaagg
    10021 agaagttttg ccaaaagcac cttggttctt tgcccacctg acaaagaagt tacatccgta
    10081 tccatgccaa agtccataac accaagagca cgcgctactt cgtcaatctt agcatccaag
    10141 gtatagaaat cacgactctc cagacggtct tgaagttctc ctacttcttc catgagagca
    10201 tcaacatccg cgccgtcttc agccattttc atatagaggt cattgatacg agcttcagct
    10261 ttaaaaagct catcaaaagc cgtacggaga acatcacgca ccgactgtct ttcagcaagg
    10321 acagagtgct gatccaagta accagccgtc acatatttgg accactcaac ctttccttca
    10381 tctggcagca ttttaccagt cacgatactc ataaaggttg attttccttc accattggca
    10441 ccgaccaggc cgatatgttc tcccttgagg agacggaagg acacatcttc aaaaattgca
    10501 cggtcaccaa aaccgtgact cagattttta acttctaaaa tactcatttt aattccttat
    10561 cttgttttta tgtaatcgtt tataaaggag ccaagccaga tagccaccca aagtgttggt
    10621 ccacaaatca tcaatctcaa agacgcgatt gaaatcaaag aaaaagtcca agattaattg
    10681 cgtacactcg attccaagac tcacaagaaa actaaaaaga aggacctttt ttgttttccg
    10741 caaatttgga aatagataaa ggagttggaa aatcagagga aaaaacaaga agacattgag
    10801 gacattttgt aaaaaaatcc aacataattg tccaatgtca ctcacttcgc ccagtttcca
    10861 gagagaattg aaaggagtca aaagaaaaac caggcgtcca agatgctgaa tacctggagt
    10921 tcccactccc acggtagatt gttcttgagg agtaaagcaa aaacagacaa tgcaaatgct
    10981 atagaaaatg actccccaga ccaaaatatg attataagtc ttcttcatca ttaaggattt
    11041 accgctgcga ctgccttctg gcggtcacgt ttcattgtgt tagagcgcaa ttgtccacaa
    11101 gctgcgtcaa tatctgtacc atgctcttga cgaaccacac agttgacccc ttttttctta
    11161 agcgtatcat agaaagccaa cacgcgctct ttgggactac ggctatattg gtcatgctca
    11221 ctaactgggt tataaggaat caagtttaca taagacaatt tcttgatgtt cttgagcaat
    11281 tcagtcaatt ccaaggcttg ttctacactg tcgttgactt cattaagcat gatatattca
    11341 aaggttacac gacggtttgt tgtctcaatg tagtattcaa tagcagcaaa gagtttttca
    11401 atcggaaagg cacggttaat cttcatgata cttgaacgaa gttcattgtt aggtgcgtga
    11461 agagacacgg caagattgac ctgaacccct tcatcagcaa agtcacgaat tttatgagcc
    11521 aaacctaagg ttgaaaccgt gatgtgacga gcaccgatag tcattccttt atcatcattg
    11581 atagtacgaa agaaattcaa gacattgttg taattatcaa agggctcacc gattcccatg
    11641 acaacgatat ggctgacgcg ttcatcctga ccacgctcat caaagtattt ctgaaccagc
    11701 atgatttgcg ctacgatttc accgttattg aggtcacgtt gcttcttaat caaaccagag
    11761 gcacagaagg tacaaccgat attacagccg acctgagtgg tcacacagac agataaacca
    11821 tagtgttgac gcatgagtac agtctcaatt aacataccgt cgggcaattc aaagagatat
    11881 ttgactgtac catcagcaga ctcttgcaca atacgttgtt tcaagggatt gaccacaaac
    11941 tggtcattga gcttagcaat caaatccttg gaaaggttgg tcatttcttc aaatgactgc
    12001 acacgtttac ggtagagcca ttcccagatt tgatctgcac ggaatttctt ttctccctgc
    12061 tccaataccc attcctgcat ggtttgatgt gccaaactat gaattgaggg tttcatttct
    12121 tctccttatt ctctactcac ttctgacgaa tgacaaaatg acgttgtccc ttgtcctctt
    12181 tctgagaatg ctggtctttc tgacgacgtc tattcttctt atctgcattc gactttcgtt
    12241 tagtttgagt cggtttcttt ccttttctag aaggtgtttc ttcttccgtc ttacgcattt
    12301 tcttgtcaaa tgatgctcgc ttaggggctt cattttctaa gacaaaatag gcacaaccat
    12361 aactacaata ctctaaaagg tagtcttgta aacgactgat tttttcaagt ttttcttctg
    12421 ttcggtcatc cttgtaaaaa cctcgtaggc gaagctgttc gttgctccag tcccccacga
    12481 tataatcaaa cttggttaat acttctgaaa aacgctgatt aaaagtcgtc acatcaaagg
    12541 catccttgat attttcaacc aaggaaaaag ctatcccttc cgtttcgacc ttgtccccgt
    12601 gtaaatggaa ctccggacca ggaaacttgt tatagttgta taattcaggt gcaatttctt
    12661 ttcgcataga tatccttttt ccacgattac ttaatacttt attctaccat aatttctagc
    12721 agttagcacg tttctcataa aaatgaaaaa agtctgacga ttttgtcaga ccagaatctt
    12781 ataacctaaa aagagaagaa caattcttcc ctccaactat cattatttag cagctgcgta
    12841 caattcatct actttattcc agttgattac tgaaaagaaa gctttgatgt agtcaggacg
    12901 cacgttgcgg tatttcacgt agtaagcatg ttcccaaacg tccaagccca agattggttt
    12961 tttaccttct gagattggtg tgtcttggtt tgctgttgaa gtcacttcaa gtttcccttc
    13021 tttgttgaca accaaccatg cccaacctga accaaaacga gttgttgctg ctgcagtgaa
    13081 ggctgcttgg aattcttcaa atgaaccaaa tgttgcatcg attgctgctg ccagttctgc
    13141 tgaaggagct gttttctcgg gagtcatcaa ttcccagaaa agagcgtggt tcaagtgtcc
    13201 gccaccattg ttgataagtg cttgacggat atcagctggg atagattcta catcagcaag
    13261 caaggcttca aggtcttcac cgatttcagg gtgtttttct aaagctgcat tggcattgtt
    13321 gacataagtt tgatggtgtt tgtcatggtg caaatgcatt gtttccgcat cgatgtatgg
    13381 ttccaaagcg tcgtatgcat atggaagttc tggtaagata atagccatct gtaatacctc
    13441 tttttctttc tatatgaaaa tgataacgca aacattcact tttttcaagt tttttgctta
    13501 tagataagga aatcactgac atactttcta ataaaataag caaatcagca agaaacccac
    13561 gacaagataa tcctgacgcg ggttgtagtt tcaacaaatg tcaattgacc tgactagcaa
    13621 tctgtaagag tgccttttca aaaaggaaac ctttttcata aagacctgtc ttaatctgat
    13681 agtctgtctc aatcaaatag gaaatagctt gcttcagaaa gctcaaagaa agtcctctcg
    13741 aatctcttaa tgcaaacttg atttgataag gatttgggtt acgtcccaga taactaccta
    13801 aactacttgc aatctgcgat tctgtttggc cagactccgc caaaatcttc acctgagtaa
    13861 aagtccgaaa ttgtcccagc atgactgcaa tcagtttgat ttcatcttcc ccttgcaagg
    13921 tcaagtctct caccaaatcg cgcgcctgat ccatcttttt agtcagaata aactgagtta
    13981 aatcaaaaat attgtcctgc aaggtcttgg gaattgcgtt aacaatatcc tcttcctcga
    14041 taacagaatc cgccttatag gactgtaaaa agagaagatt tttctggatt tcgctaaatt
    14101 gaaaccccga cttgatgagg agattttcaa aagaatgatt ggtaaactgc agaccttgtt
    14161 tctgactcca cttttggaaa tactggcgca attcttgttc ttttacttct actgcatcga
    14221 agaccttggc atcacgctta agtaatttga ctaaccgtct tttgctatcc agctttcctt
    14281 ctgcaaagat tatcaacttg gttgttggag aaggattgtc aaggtattcc tcaaatgact
    14341 taagctcatc atctgtcaaa aagcgtttct tagcagtcgt gatatccata aaataatcta
    14401 atatcacgat tttctcatcc gcaaagaaag gaaggctgac caactccagt tccacatcct
    14461 tgtaaactac ttctttcata tcaaagtagg caaagttgag gtcagcagaa tcatacccaa
    14521 tctgtttcaa cacttgactc ttcatcactt caaactgacc ctgatctgtc cctgtaaata
    14581 ggctcaggct cggtaaattt gataaagtca acttctgact ttcttcaatg gctagcatcg
    14641 tctctccttt cttcagattt ttcgatttaa tttagtcaat atagcgcaat ttcccacgga
    14701 aatcttctaa gctctcgtag cctttttcca ccatgattgc tttcagttca ttggtaatgc
    14761 ggtcaaaagc actgacgcct tctttgtgaa gggtcgttcc cacctgcacc atacttgctc
    14821 cacagaggat gtgttcaaag gcatctcgac cagtcagaac gccacctgtt ccgataattt
    14881 ggatttgagg atttaaacgt tgataaaagg cgtgaacatt ggctagagca gtcggtttga
    14941 tgtattctcc accaattcca ccaaaaccat tcttaggccg aataacgaca gattcgtctt
    15001 ctatatagag gccgtttccg atagagttaa cgcagttgac aaacttgagc ggatatttgt
    15061 tgaaaatagc tgccgcttga tcaaagtgaa caatatcaaa ataaggtggc aatttaattc
    15121 caagaggttt ggtgaagtaa gcaaacactt ctgccaaaat ccggtctgtt gtctcaaaat
    15181 cataggcaat ctgaggttta cctggaacat ttggacagga aagatttagc tcagtcagac
    15241 cacgaaaatc actctcttgg acttttttca aaatagtatg ggtttcctct ggagacatgc
    15301 cgaccagaga taagaagaaa gttcggttcg actctttttc ctgcaaatct aaaagataat
    15361 ccaaataata gtctaagcca ttatttggca agcccataga gttgatggaa ccaagtggaa
    15421 catcttggta gcgtggctca ggattcccct gacggaagtc caaggtcgct gtcttagtaa
    15481 caaaggttcc tgccgctgag tttttgacct cttctaactc ctctatcgtc atacaagcca
    15541 cacctgctgc attcatcaag caattgtcaa actcaaaacc agcaatttgt gttttcgttg
    15601 ataccatgat tctaatcctc cagatttctt ttattgctaa tattatacca taattttaat
    15661 tctaggttta ctagattctg tggttctatc tatttattcg gaaaagaaag tctagtacag
    15721 aagtcatgct atggaaacag ctagtgtatt agaagtttga acaaggcttg ggtaacagac
    15781 ttttgaatga agtccaagca acaaggagaa atctcaacca tgagtccatt ccatgactct
    15841 gttgctctag aaaaccttgc aatagtcaag tgataacgaa taaaactttg gattgaaata
    15901 tccccaagat tatctattac gaggagaaat cttaaccttt atcattttta aagaaatata
    15961 gtaaaatgaa acaagaacag gagaaatcga tcaggacagt caaattgatt gctaacaatg
    16021 ttttagaagt tgaggtgtac tattctagtt tcaatctact atacatgtaa atctctactt
    16081 tcgcaaaatg gattttcaga acagtatccc agtatagtta aaaactataa aaaagagagg
    16141 acgttcccct cttaaaatct tattttactg cttctttcaa agcatctacc ttatccaaac
    16201 gttcccatgg aagatcaata tctgtacgtc ccatgtgacc gtaagccgat gtttgacggt
    16261 aaattggacg cttgaggtcc agcatttgga taatccctgc agggcgaagg tcaaagattt
    16321 gacgagccgc tttttcaagt tgactttcag ctactgttcc tgtaccgaaa gtatcgatac
    16381 gaacagaaac aggttgcgca acaccgatag cataggccaa ctgcacttct gccttcttag
    16441 caaggcctgc tgcaacgata ttcttggcaa tatagcgagc cgcataagag gctgaacgat
    16501 ccaccttagt cgcatcttta ccagagaagg caccaccacc atgacgagag tagccaccat
    16561 aagtatctac aataatctta cgaccagtca aacctgagtc cccttgagga ccaccgatta
    16621 caaaacgacc tgtcggattg ataaagaatt ttgtcttatc atcaagataa gaagatggaa
    16681 taacttcttt gatgaccttg tcaatcacat cttgatggat ttgttcatta gtggcctctg
    16741 gatcatgctg agtagaaata acgactgtat ctacacgtac cggacggtca ttttcatcgt
    16801 actcaactgt aacttgtgat tttgcatctg gacggagata gctaatttct ccagacttac
    16861 gaagttctgc cagacgacga accaatttat gactgagtgc aattggcaat ggcataagct
    16921 cttctgtttc atctactgca aatccaaaca tgagcccttg gtcacctgct ccaatcaagt
    16981 ccagtggatc ttgatcagca tttccacgaa cctccaaggc ttcgttaaca ccttgagcga
    17041 tgtcaggaga ttgttccacc aaagatgggt gtactcccac cgtctcagca gaaaatccat
    17101 attctgtatt ggtataacca atctctgcaa tggtatcacg aaccacacgg ttaatatcca
    17161 cataggcatt tgtagaaatt tcaccaaaaa cgtggacaga accagtatat acagctgttt
    17221 cagcagcaac gtgcgcctct ggatcctttg ctaaaatagc atccaaaatc gcatctgaaa
    17281 tttggtctgc aatcttatcc ggatgcccct cagatacaga ttcagacgtg aataatttac
    17341 gttctgacat aaaaatgtcc ccccttaaaa aatattgtta tagagttaca aagtactgat
    17401 aggaaaactc ttcgtaataa atacctacca tcttatcggg actatataac tttatcatta
    17461 taccattttt aatcgcaatt tgcagtcttt aatgtagtgt ttcggtttag atagttcgtt
    17521 ctcataaagc aaaaagttgg agctcagtac tccaacaatt tctattaaaa tgtttgacgt
    17581 ttagctttac gctctgcacg accgcgagcg cgattttcag cacgcttggt tttacggcgc
    17641 ttttcatcaa ccgcccattg aattttcttc ttataacccg gtttgacttt tttctttttc
    17701 tttttaacca aaccaatcat ttcgatatca agtttatctt gttttttctc acggttggca
    17761 cgacgatcac ggtcataggt atcttgaaat tccccgtctt tgaccatctt aggactaaac
    17821 ttgattccca atttctccaa ctcacggata tccgagtcat cacttggctg ataaagggta
    17881 atagctgtac ctggtaggcc atttcgtcca gtacgaccaa cacggtgaac aaaaaaagat
    17941 aagtcttgcg gaatggcatc attgatgaca tggctgacac cttcaatgtc aatcccacgt
    18001 gctgccaaat ctgttgcgac aatatactca aaatccagat tttgcacctg attcatgatt
    18061 cgcttgcgtt cacgaggggc aatatcgcca tggatttttg caaccttcaa gccttgagca
    18121 gtcagatatg aatgcaattc atcagcacgc gttttagtgt taacaaaaat cattgccaaa
    18181 tacggctgca tcaactgagt caactggtaa atttgagcat tcttatcatg tcccttggtc
    18241 gaaatcaacc aattatcaat ggtgtcagaa ataaccgttt tggtcttaat tttctccata
    18301 acaggattgg ataagtattt tttcaagaat ggttgcagtt tttgtgggat agtcgctgag
    18361 aagaccatga attgcaagtc ttttggaaga ctgccagcaa tcttatcaac agtttccaag
    18421 aatcccatat ccaaggtcat atccgcttca tcaacaacaa atgtcttggc tttatgaata
    18481 gctaaatcac cagatttaac caagtcgtag atacggcctg gtgttccaat aacaatatga
    18541 ggctgattgc ttgccaattt ctcaatctgg cgagccttat ccgtaccacc cacataatta
    18601 accacacgaa cttcgacatc tgagtgagct gaaatctgac gcgctacttg gtaaatttga
    18661 gtagccaact cacgactcgg tgcagtaatc actgcttgta cactatcgct agcttcatct
    18721 aattgctgga aaatcggtaa caagaaagta tgagtcttac ctgaacctgt ttttgattct
    18781 cctactaggt cacgacctgc caaaacaata ggaatcaact tgtcttgcac ctctgttgga
    18841 gttgtaaatt ttaactcctc caaggcttct ctaatatagt ttttaaattg aaatttcgta
    18901 aatgacataa catcctcgat tctatctatc ttatcaatta taccatattt tattccatta
    18961 cagtagtctc acttatttag gctatttcca gtagcttctc tagtaagaaa aggctggaat
    19021 tttatacccc aattattcac ccctaatcta aaaa
//
LOCUS       DAVLZG010000040        18951 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLZG010000040 DAVLZG010000000
VERSION     DAVLZG010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.040"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..166)
                     /gene="blpU"
                     /locus_tag="VYO72_001367"
     CDS             complement(<1..166)
                     /gene="blpU"
                     /locus_tag="VYO72_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1707729.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGA"
     gene            complement(369..659)
                     /locus_tag="VYO72_001368"
                     /pseudo
     CDS             complement(369..659)
                     /locus_tag="VYO72_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(705..938)
                     /locus_tag="VYO72_001369"
     CDS             complement(705..938)
                     /locus_tag="VYO72_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1707730.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(944..1936)
                     /gene="plsX"
                     /locus_tag="VYO72_001370"
     CDS             complement(944..1936)
                     /gene="plsX"
                     /locus_tag="VYO72_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1707731.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1933..2703)
                     /gene="recO"
                     /locus_tag="VYO72_001371"
     CDS             complement(1933..2703)
                     /gene="recO"
                     /locus_tag="VYO72_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1707732.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2700..3869)
                     /locus_tag="VYO72_001372"
     CDS             complement(2700..3869)
                     /locus_tag="VYO72_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1707733.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLKDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            4018..5028
                     /locus_tag="VYO72_001373"
     CDS             4018..5028
                     /locus_tag="VYO72_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1707734.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVINAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(5213..5650)
                     /locus_tag="VYO72_001374"
     CDS             complement(5213..5650)
                     /locus_tag="VYO72_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1707735.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5735..8368)
                     /gene="polA"
                     /locus_tag="VYO72_001375"
     CDS             complement(5735..8368)
                     /gene="polA"
                     /locus_tag="VYO72_001375"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1707736.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8621..8974
                     /locus_tag="VYO72_001376"
     CDS             8621..8974
                     /locus_tag="VYO72_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1707737.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            9189..9305
                     /locus_tag="VYO72_001377"
                     /pseudo
     CDS             9189..9305
                     /locus_tag="VYO72_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            9298..9531
                     /locus_tag="VYO72_001378"
     CDS             9298..9531
                     /locus_tag="VYO72_001378"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707738.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            9659..9801
                     /locus_tag="VYO72_001379"
                     /pseudo
     CDS             9659..9801
                     /locus_tag="VYO72_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9938..10906)
                     /locus_tag="VYO72_001380"
     CDS             complement(9938..10906)
                     /locus_tag="VYO72_001380"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1707739.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(11051..11674)
                     /locus_tag="VYO72_001381"
     CDS             complement(11051..11674)
                     /locus_tag="VYO72_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1707740.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSPFLNA
                     FESAIVAPLVEEPLKLLSLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(11656..11865)
                     /locus_tag="VYO72_001382"
     CDS             complement(11656..11865)
                     /locus_tag="VYO72_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707741.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            complement(11890..12387)
                     /locus_tag="VYO72_001383"
     CDS             complement(11890..12387)
                     /locus_tag="VYO72_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1707742.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(12460..13821)
                     /gene="radA"
                     /locus_tag="VYO72_001384"
     CDS             complement(12460..13821)
                     /gene="radA"
                     /locus_tag="VYO72_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1707743.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(13835..14350)
                     /locus_tag="VYO72_001385"
     CDS             complement(13835..14350)
                     /locus_tag="VYO72_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1707744.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(14352..14795)
                     /locus_tag="VYO72_001386"
     CDS             complement(14352..14795)
                     /locus_tag="VYO72_001386"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1707745.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(14852..14949)
                     /gene="ffs"
                     /locus_tag="VYO72_001387"
     ncRNA           complement(14852..14949)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYO72_001387"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(14982..15449)
                     /locus_tag="VYO72_001388"
     CDS             complement(14982..15449)
                     /locus_tag="VYO72_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1707746.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(15650..16936)
                     /locus_tag="VYO72_001389"
     CDS             complement(15650..16936)
                     /locus_tag="VYO72_001389"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1707747.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(17167..17403)
                     /locus_tag="VYO72_001390"
     CDS             complement(17167..17403)
                     /locus_tag="VYO72_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1707748.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            17668..18465
                     /locus_tag="VYO72_001391"
                     /pseudo
     CDS             17668..18465
                     /locus_tag="VYO72_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18500..18709)
                     /locus_tag="VYO72_001392"
                     /pseudo
     CDS             complement(18500..18709)
                     /locus_tag="VYO72_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18875..18948)
                     /locus_tag="VYO72_001393"
     tRNA            complement(18875..18948)
                     /locus_tag="VYO72_001393"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18912..18914),aa:Asn,seq:gtt)
BASE COUNT         5721 a         4576 c         3266 g         5388 t
ORIGIN      
        1 ctgcaccttg ccatgttctt gttttaattc ctagctgaag acctcgtgct gctcctcctc
       61 caacacctgc tttggcaaaa tctccccaat tgcatccgcc accttcaacg caagcaagca
      121 tctcagtatc cataatttca aattgtgaca tcttttttgt attcataacg aatacctctt
      181 ttttattttt aatatttgtc ttgttacaaa cttgacaagt ttagtataac agtatctatt
      241 aatttttttc atccaaatct tgaattggca tcgaaacgtc ttgaattagc ttttttgttt
      301 caaaatcatc tctattttta aaaaagatgt tttctaatca cttttttact attagacttc
      361 ctgcaaaact agaatcctag ttcatgattg ataataccag caatcaaatt cattcgtaat
      421 ccgaagcgtt tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt ttttactttg
      481 gcaaagatgt tctcaacctt gcttctctcc ttagatagcg catggttaca ggctttatct
      541 tcaactgtta gcggcttgag tttgctggat ttacgtggag tttgtgcttg aggatatatc
      601 ttcatgagcc cttgataacc actgtcagcc aagattttac cagcttgtcc aatatttctc
      661 atttctaaaa accatctact tccgttgact tggaactccg attgctattt tccttgaatg
      721 attttaacca catctcctac actttggagt tggtcaattt cctcatcgct gatttcgata
      781 ctaaattcat cttccagagt caagataaac tccatcaagt caacagaatc cgcatccaaa
      841 tcgtctttca gactcaagga ttctgtcacg acaaagtcct ctccctgtcg ctcttggata
      901 atggtcacaa tacggtcaaa aatttctttt tctgtcatct cttttattct cctgaaaatt
      961 cacgcgcagt ctgggcaacc acgtctgttt ctagcatggt acgaatctga cgaatcgtac
     1021 tataaacagc cttggcatcg cttgagccat gagtcttgac aacaggtgcc ttaacaccaa
     1081 acaagaccgc tccaccaaca tctgaataat tgagctgttt tttcaaacca ctgaggctgt
     1141 ccttgagaag gagggcacct agtttcgctc gaagaccacc acctgtaata gctgtcttga
     1201 gcaagcccac gattcccata gctgtccctt cgatggattt gagcacagcg tttcccgtga
     1261 aaccatctgc cacaacaaca tctgcaacgc cattcatcaa atcacgcgct tccacgtttc
     1321 cgataaagtt caaactttca tcagccgcca gtaattcata agtttcctta cgaagcgggt
     1381 cgcccttgct actctctgtt ccgttgttga gcaaaccaac gcgtggttgc gcaatgccac
     1441 ggacattttt agcatagaag gaacctagaa ccgcatattg atggaggtgc tgggctgtat
     1501 tttctgcatt ggcaccaagg tctagcatgt caaaaccttt tccatcaacg gtaggcaagg
     1561 tagacatgag tccaggacgg tcgatattct tgatacgacc cacgatgaag aatcctgctg
     1621 ccaacaaggc acctgtattc ccagccgaaa ggacagcgtc tgcttcacca tctttgacag
     1681 ccttggctgc caataccata ctggcatttt tcttattcct aatagctctc gtaggttcat
     1741 catccgaatc aatcttctca tccgtatgga taatgctgac gcgctctgtc gctgtcagat
     1801 attgcttgat tttagcttca tctccgtaaa gttgaacctc gatatctgaa aagtcagata
     1861 gggcttgatt gacaccctca acaatggcct gaggtgcgta atcgcccccc atggcatcta
     1921 ctgcgatttt tttcatttct tttcctcttt tagtaattgt ccccagtctg ctagggaatc
     1981 aataaatttc tttgatttta ggtgaatccc aacgtactct tcatataatt gatccataaa
     2041 ttggcgtagc tcttgcttga ttccaggctt gagcgaaatg gtctccaaag tctcaaaatc
     2101 aatagcttga aattgattga gcagataggg gatattggga ttgagatgac aacgtctctt
     2161 atcctcatga taatgctctg gacagaggca ggctccatat ttgaaagaaa agtcaaaagc
     2221 ctgaccaacc cgatggcaga agacacactc attaaaattg aggctgattc caaatcgagt
     2281 caaaatttga atttcaaaaa tattggtcaa aacctgataa tccaagcctg cttccatcaa
     2341 ctccaaagtc ttttgcaaaa aagcaaacaa gggagcatcc tgctgattgt cctgcaaact
     2401 agcatctgca agagctgcca cataggtcgc ataggccatg acaaagaggt cactattaat
     2461 cttgggaaaa gtcatgacct catgatagtc ttcgatgtaa ctgagtccgt catcattgat
     2521 tcgcaagaga aatcgtgcca acaccaaggg ctgaataaca ggcgccagct tagactgacc
     2581 agcgtgtttg acaaaaaaca tgcgtttgcc aacctgctct gtaaaaattt tgacgagctt
     2641 gtcatcctca cgaaaattgc gattgtaaag caccaagcct tgactcgtga tagactgaat
     2701 catgcttctc tcatgtactc ctcaagtcgt ttcatggctt ctttgatagt ctccatgctg
     2761 gctgcataag ataggcggac gtagccttcc ccgtaacgtc caaaggctgc accagggata
     2821 aaggcaacgg ccttcttctg agcaaaatcc ttcagaaaag caaaggagtc ttgattgtag
     2881 cccgctggaa ttttagcaaa aatatagaag gcaccgtctg gtttgataat ctcaaaacca
     2941 agagcagtca ttttttcgat gatatagtcc cgacgctgga tatattcctt cttcatgggc
     3001 tccgcatcat ttttaccagc cgtcaaggct tctaccgcag catgttgcgc catggtattt
     3061 gcggcagtga ccaagtattg gtgactcttg attaactggg ctgtgaaggc cgcaggagcg
     3121 aaaatcagcc ccaaacgcca acctgtcatg gcatgcgatt tagacaaacc attgataata
     3181 atagcctggt ctttcaacat cgttcctaga gacacatggg cttcgcctgt gtaggtcaat
     3241 tctgagtaaa cctcatcaca gacaacaaaa atttcgtact tgcgtaaaac agctgccaag
     3301 gcctctaact gctctcgact gtaggtaatt cctgtcggat tggctggata gttgagaata
     3361 accgctttga gcttatcacc ctgctccaaa atggccttct ccaacatctc aggagtcaag
     3421 acaaaaccat tttcagtcgt atcaatctca acaatttctg ccccaactaa gttaacaatc
     3481 ggttcatagc ctggataagc aggagctggc aaaagtacct tgtctccctc ttccaaaata
     3541 gccgtcaaag tcgcagataa agcctctgtc gccccaattg taaccaagat ttcattttca
     3601 ggagcatagt ccagttggta cttttcctta acaaagtcac tagctgcctg acgtagagtc
     3661 agcagaccac tcatccctgt atagtaggat tggttctgat caatcgctcg cttggccgcc
     3721 tccttgacat ggtctggcgt tgtaaaatca ggttccccca aggtcaaacg caagacccca
     3781 ggaatctccg aaatagcctg gtcaaactga cgaatcaacg aaacttgaat cttatctaac
     3841 tgtttattaa agcgcttagt taagtccata gatacctcct actttcaaaa cgtatctcta
     3901 ttatactaca aaagcctccc gaccgcaaaa atacattaga gaatagcttt ccactttcta
     3961 ttttactttt cctgtttata ggtctataat ggtaatagat tttatttgga ggtttttatg
     4021 tcatttctat caaaaaatgg agcaggtatc ttggcctgcc ttctcatttc tatcgtatct
     4081 tggtacttag gaggattctt ccctgtgatt ggcgcgcccg tttttgccat tttcataggc
     4141 atgctcctac atccctttct ctcgtcctat aaacaactgg atgctggttt gacctttagt
     4201 tccaagaagt tgctccaata tgccgttgtc ttgcttggtt ttggtctcaa tatctcgcag
     4261 gtcttcgcag ttggccaatc ttcactccct gtcatcctgt ccactatctc aatagctctg
     4321 attattgcct acctcttcca gcgtttcttt gcactggata caaaactggc taccttggtt
     4381 ggagtaggtt cttctatctg tgggggttct gccattgcag cgacagcgcc cgttattaat
     4441 gctaaggaaa aggaagtagc ccaagccatt tccgttatct ttttcttcaa tgtcttggct
     4501 gcgctcatct ttccaaccct cggcacctgg cttcatctat ccaatgaagg cttcgccctc
     4561 tttgcaggga ctgcggtcaa cgacacttcc tctgtaacgg ctgccgccag cgcttgggac
     4621 agtctttacc aaagcaatac cctcgagtct gcaaccattg ttaaactcac acgtactttg
     4681 gccattatcc ctatcacgct ctttctatcc tactggcaaa gtcgccaaca agaaaacaag
     4741 caaagcctac aactgaaaaa agtcttccca ctttttatcc tttactttat ccttgcctct
     4801 ctcctcacta cactactcac ctctctaggt gtgtccagta gtttctttac ccctctcaaa
     4861 gaactctcta aattccttat tgtcatggcc atgagtgcta tcggtctcaa aaccaatctg
     4921 gtcgctatgg tcaaatccag tggaaaatcc attcttcttg gagccatctg ctggattgcc
     4981 atcatcctca ccactcttgg tatgcagacc cttatcggca ttttctaaca ctcttcgaaa
     5041 atctcttcaa accacgtcaa cgtcgccttg ccgtaggtat atgttactga cttcgtcagt
     5101 tctatctgca acctcaaaac ggtgttttga gcaacccgca gctagtttcc tagtttgctc
     5161 tttgattttc attgagtata acacaaaagg tagcccatca gctacctttt tcttatgctt
     5221 cctcaatcaa gcgagtatgt tctctcttga tacagcgatt catcacgata tcatcacatc
     5281 caccatcacg caaaatctct tttgcttcta aactttcaag tcctagctgt gcccaaaaaa
     5341 tcttggcatc agctttgaga aaatcacgcg ccacatcggg cagaaattca ctgcgacgat
     5401 aaacattgac aatatctaca ggaaaaggaa tttcagcgag gctagcataa gccttttcac
     5461 ccaagatttc gccacctgcc gccttgggat tgactgggat gattttatag ccccgagcct
     5521 gcatttcctt tgttactcga ttgctggttg tttcttcacg gtcagacaaa cccaccacag
     5581 caagggtttt actcgttgcg agatactgac gaatcacgcc atcacttgga ttgataaatt
     5641 cttgactcat agaaatcctc ctttttcatc agtatagcac attttgaaaa ggtttgcaga
     5701 attctactac aaaaaaggag gactagcccc ctttttattt agcctcgtac caggttgccc
     5761 cttcattctc atctgcgata agaggaacac tgagttgaat ggcttcttcc atggtttgtt
     5821 tcaccaattt ttttatctct accaattcag atttaggcac ttcaaggacg atttcatcgt
     5881 gcacttgtaa cagcatctta gtctgataac cacctgcaac caaggcttta tccagctgaa
     5941 tcatggcaat cttgagaata tctgctgccg aaccctggat aggtgagttg atagcagttc
     6001 gctccgcaaa accacgaata ttgaagttgc gcgaattgat atctggcaac tcacggcgac
     6061 gcttaaagag ggtctctaca tagcccttat cacgcgcctc ccgcaccact tcatccatgt
     6121 agtttttaat acctggaaaa cgttcaaagt aggtatcaat gtaggctttg gcttccttac
     6181 gactaattcc caaattatta gacaagccaa agtctgaaat cccataaacc actccaaagt
     6241 taactgcctt ggcattgcga cggtcatttg cagtcacatt atcaggacgc tcaatgccaa
     6301 agacccgcat ggctgtcgaa gtatggatat ctgccccctc ttggaaggcc ttaatcaagt
     6361 gctcatcctt agaaatatgc gccaaaacgc gcaattcaat ctgtgaatag tcagagctga
     6421 gtagcacact atcctcccac tctggcacaa aagccttccg aatcaagcgc ccttgttcca
     6481 atcgggcagg aatattttgc aagtttggat ccacactaga caaacgcccg gtctgggtca
     6541 aatcctgcat atagcgagta tgaatctttc catcagccaa aatccagtcc tgcaagccaa
     6601 ttacataagt agattgaatc ttagcaattt gacggtaatc caggattttc ttaacaatcg
     6661 gagcaatagg agcgagacgc tccaacacat ccactgctgt cgaataacct gtcttggttt
     6721 tcttagtgta ttctagagga agtcccaatt tctcaaagag aagcacgccc aactgcttag
     6781 gcgagttgac attaaactcc tcaccagcca gctcgtaaat ctcttgagtc agtttttcaa
     6841 tgacaagctc attttcagcc tgcatctcaa gcaaggtctc tttcttgacc acaatcccag
     6901 caatttccat cttggcaagg acaaaagcca gaggttgctc catatcataa agaagctcta
     6961 attgcccatt ttcgctaagt ttttcaagta aaataggctc tgtttctacc aaaacagcaa
     7021 gtttacaagc taagtgttcc aagaatttct cacgttcagg aatggccttt ttaacaccct
     7081 taccgtagaa agtttcatca tcaaccaagt aagtctgacc ataaagacta gcgatggtcg
     7141 caatttcatt gtcctccaca gtcgaaagga ggtatttagc caaacggatg tcaaaagcag
     7201 gcgcctgcaa atctacacca aaacgttgca aaagaacttt aaccttctta aagtcataaa
     7261 ctctcagaga tgttttttct aagaaatcct tgaaaatcgg gtcttgcaac agctcaagct
     7321 tgtctgtggc atagagctga tccccacaag accaggcaaa tccaaccaaa ttatctgtat
     7381 ggtaattctc accaaaaagc tcaaagtgga agatagactc ttcactcagc atatcttgac
     7441 tgatttggtc aacaatagta aaatccaaac cctcagccac atcagctgac gacatattta
     7501 aagcctgctt gagctgtttg aagcccatct catcgtagaa tttcccaaga ttttcaacat
     7561 ctggaccact atagaccaag tcctctaaac caatcgcaat cggtgccttg gtatcaatgg
     7621 tcgctagtgt tttagacaaa aaggcctgtt ccttgtcatt gatgagattt tccttcatct
     7681 tagaagtctt cattccatca atattttcat aaatcccctc aagcgaacca tgctccagca
     7741 agagcttaat acccgtcttt tcaccgactt tggtcacccc agggatatta tccgacttat
     7801 cacccatgag cgccttgaga tcgataaact gagctggtgt gaggcccatt tcttccatga
     7861 ggtaatctgg cgtaaaggcc tcaaactcag ccacaccttt cttggaaatt tcaaccaccg
     7921 tatgctcatc cgtcagctga atcaaatcct tgtccccact gacaatggta atatcaaaac
     7981 catcctgctc tgctagctta tccagcgtcc caatgatgtc atccgcctca tactgagcca
     8041 gctcatagtg acgaatcccc atatgatcca gcaactcacg aatgaaagga aattgctcac
     8101 gaaactcatc aggagtcttg gcccgaccac ccttatagtc cgcatacatc tctgtccgga
     8161 aggtcgtctt tcccgcatca aaagccacca aaatatgact cggctcaacc cgctccaaca
     8221 aatgactcaa catcaactga aaaccataaa tcgcattggt atgcaaacca gccgcattct
     8281 taaaacggtc caactgctga tacagcgcaa aaaacgcccg aaaagctaca gaagacccat
     8341 caatcaataa taattttttc ttatccatac acccattata aaggaaagaa tcaaaaaata
     8401 ccattgggaa gagctagagc aagtattttt caaacttttt ccgaataaat agatagagcc
     8461 agagaattta gtaaacctag atttaaaaat gtgctataat atagtatatt gaatctataa
     8521 tagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct gatagagttg
     8581 ttcacatctt atttcaattc actatagaag gaggaaaagg atgattctca gacatctggg
     8641 aattagcccg accaatgact tggttgctaa gaaaattttc agcaacccag aaatcacttg
     8701 tcaatttatc cgcgatatgc tggacttgcc agccaaaaat gtgactattt tggagggaag
     8761 taacattcat gtcttgcctt ccatgcccta ctcagcgcag gatttttata ccagtataga
     8821 cgtcttggcg gagttggata acggtactca agtaattatt gagattcaag tccatcatca
     8881 gaattttttc atcaatcact tgtgggctta cctgtgcagt caggttaatc aaaatcttga
     8941 aaaaattcgt cagcgagaag gtgatactca ctagatctac aaacacatcg ctcctgttta
     9001 cgtcattgct atcgtggata gtaattattt ctcagatgac ctggcttttc atagctttag
     9061 tatgcgcgaa gacacaacag gtgaggtatt ggcgattacc aacaatggac aggaaaacca
     9121 tctggttaag atggcattct tggaattaaa aaatacagag aaaccagcaa agacaaggtt
     9181 cgcaagccat ggttggagtt tttcggcaac aagcccttta cccagcaacc gcaacgagcc
     9241 attagccaag caaatcaact gctggactac aagagctggt ccgaggagga caggaaaatg
     9301 tttagtcaac tacatatgcg agaagaacaa gtcttgttag cacaggacta tgccttggaa
     9361 actgctaggg ctgaaggcct tgaacaagga ctagagcgtg ggaaagttga aggaagggca
     9421 gaaaggaaac tttttgcctt cctagacata gtacgccaag gtcttctgac ttctgaggtt
     9481 gccagccagc aattaggtat gtcagtatct gaatttgagg cactgttgta aaatggctcc
     9541 ataatatcca tagtgggtaa atcccctatg gatattatgg agcctatttt gtgtaaaaaa
     9601 aaaagtccca tatgacctat aatgaaaagc gacaaaacaa ctcattagaa agaatcatat
     9661 ggaacaatta cattttatca caaaattact agacattaaa gaccctaatg tccagatttt
     9721 aaacatcatc aataaggata cacacaagga aagcgtcgat tcaaatgcta tcactgttca
     9781 aaaatgatgg tcgctgaaac ttatgatgac gtacagtcat atttcttttc tttttattat
     9841 atcacagttt taaatctagc tttactagat tcaccgctac tatctattta ttcggaaaaa
     9901 agacgaaaaa acctgagaat catctcaggc ttggtcatta aatttttttc tcaatatcga
     9961 aaagtggaga aagtggtcgt ttttcatgaa tacgtacgat agcatcccct aggagatgag
    10021 cgattgaaat ctgctcaatc ttatcaatca aacgctcttc tggcagatag atggtatcca
    10081 aaacaaccaa tttcttaata gctgattttt ggatattgtc cgtagcagga ccagaaagaa
    10141 ctgggtgcgt acagcttgca tagacttcaa cagcaccagc ttccgcaaga gcatctgccg
    10201 catgacaaat cgttccagcg gtatcaatca tatcatcaat caagatacaa gtcttgcctt
    10261 caaccttacc gatgatgttc ataacttcac tagtattcat cttatcaacg ctacgacgtt
    10321 tatcaataat agcgatagat gttttcaaaa attctgccaa cttacgagca cgagtcaccc
    10381 ctccatggtc cgggctgaca accacatagt cagaaccaac cataccacga cgctcaaaat
    10441 aatctgcaat cagaggagca cccatcaaat gatccacagg aatatcaaag aatccttgaa
    10501 tttgcgcagc atgcaagtcg atggtcaata aacgatccac tccagctact tcaagcatat
    10561 ttgcgacaag ttttgaagtg attggctcac gcgctctcgc ctttctatcc tgacgtgcat
    10621 acccatagta aggcatgaca acattgacag attctgcact cgcacgcttc aaagcatcta
    10681 ccataatcaa aatttcaagc agattgtcat ttacaggcga actagttgat tgtaagataa
    10741 agacgtgttt cccacggatt gattcttcaa tgttgacctg aatctctcca tctgaaaatt
    10801 ggcgaacact tgatttcccc aactctatcc caatctcctg cgccacacgt tctgccaatt
    10861 ctttattaga agaaagggca aacagcttta aatcagaaaa agacatgatt tcctccggta
    10921 tatatgtata gcttgtgctt ttcacaagat tttccatcta ccattgtagc gctttttgca
    10981 ctatttttca atcaaaaata aaagaagggc accatatttg tacccttgca tcattctttt
    11041 gaaaaatatt ctaggtcatc aactcattgt gtttctcaac aaagcaataa gcatgataaa
    11101 aaccatagag agcaatagcc gtaaccactg gaatcgctaa aggcaactct gtttccaact
    11161 ccacaaaagg agagttaaac aagaagtgag ttcccaaggc taaacctaga aaaataaggc
    11221 cctgtttctt gccaaccttc tgtcctttat aggctctgta aagcaagtaa acacctacta
    11281 cagctagacc tgaaaaagtc cagtgagagg caattcctga gatgatacgc tctaaaattc
    11341 gcgaaatagt aaagtcaaag ccctctggca aatccgtacg aatataacca atatcctcaa
    11401 tcatttggaa tcccaaaccg gaagcaattc caagtaaaaa caaagatttt aattttcgca
    11461 caggaatcaa agccaaaaca aaaacaagtg acaataattt caagggttct tctaccaaag
    11521 gagccacaat agcactttca aaggcattta aaaatggact atctgggaaa agaaccccca
    11581 gtaaatcatg gatataagta ttagcaaaac tagacaacca gcctgaaagg aacatccctc
    11641 ccaataaaga cagaatcaaa accttctttg gcaattccca tttttcccaa tacggaagag
    11701 aaaataaaga gccggaatca tgtaaaagag agctagaaag atagaaactc ccattagtcc
    11761 atattccgca cctgacctcg aaccgtccgt atagtagatg gtttcatact gtaaaccaat
    11821 acatagcaat aaaataaaaa taaataaaat actgcttttc ttcatacact ttctttctaa
    11881 atgaagtatt tataattcta cgactgtcat acttcctgta tcaacattgt aaatggcacc
    11941 agagataatg acatcgtctg gtattagggg agactcgata agcagttgca tatcctcgcg
    12001 tacactctct tctatatctt ggaagggcaa gaagtcctgg tctgacacat ctacacctaa
    12061 ttcctctttt aaatactcct gaaaaggttc attttcaaag gtctgagcac cacagtctgt
    12121 atggtgcaat accacaatct ctcttgtccc catttgttgc tgggaaataa ctagcgaacg
    12181 aatcatgtct tcagtcactc gaccacctgc attccgcaag atatgagcat ccccaagtgc
    12241 caagcccaga gcttgcgcaa cgtgcagacg agagtccata caggtcacaa tagctactct
    12301 tgttttgggt ttaagtggca gatttaactg cccatgtagg gcaacataag cctgattggc
    12361 ttgcataaac tgttcaaaat acgacacgat tccctccttg aaaatttgat agtcaaatat
    12421 ttctcctatc ttatcatttt taagagaatt tgtcacggat tatgcaaaga cctttttcaa
    12481 gacttcctga atcgttgtca cgccaatgac ctgaatttcc ttaggcagag tgattcctgt
    12541 caaggaattc ttaggtacat aaatcttagt aaagcccagt ttagcagctt cgttgatgcg
    12601 ttgctcaata cgattcacgc gccgaatctc tcctgtcaag cccagttctc cgacaaaaca
    12661 ttcctgagga ttagttggct tgtctttgta gctcgaagca atagcaactg caacagccaa
    12721 gtcaatcgca ggttcatcca atttaacacc accagcagat ttgagatagg catcctgatt
    12781 ttgcaagaga agccctgccc gtttttccaa aacagccata atcaagctag cacggttaaa
    12841 atcaagtcct gtcgtagtac gcttggcatt tccaaacatg gtcggtgtta ccaaagcctg
    12901 aacctccgcc aaaatcggac gcgtcccttc catggttaca acgatggagg aaccagtcgc
    12961 cccatccaaa cgctcttcta ggaaaacttg actcggattg agtacctcaa ccaagccgcc
    13021 cgactgcatc tcaaaaatcc caatctcatt agtggaacca aaacgatttt tgaccgctct
    13081 caaaatacga aaggtgtggt gacgctcccc ttcaaagtaa agcaccgtat ccaccatatg
    13141 ctccaacata cgaggcccag ccaaggttcc ttctttggtc acatgaccta cgataaagat
    13201 ggcaatgtta ttggtcttgg ccaactgcat gagttcagcg gtcacttcac gcacctgaga
    13261 aacagacccc tgcacccctg aaatctcagg agacatgatg gtctggatgg aatcaataat
    13321 gagaaagtct ggctggatac gctccacttc tgcacgaaca ctctgcatat tggtctctgc
    13381 atagagataa aactcactat caatatcacc taagcgctct gcacgtagtt taatctgctg
    13441 ggcagactcc tccccactga catagagaac tgtccccact tgggacaact gggttgagac
    13501 ttgtaggaga agagttgatt tcccaatccc aggatcccca ccgatgagga cgagacttcc
    13561 tggtaccact ccgcctccaa gcacacggtt gaattcctcc atctccgtct tggttcgatt
    13621 gacattgatg gaagtcacct cagctagttt catgggcttg gttttctcac ctgtcaagga
    13681 cacacgcgca ttcttgacct cggcaacctc aacctcttcc acaaaagaag accaagaccc
    13741 acagttgggg caacgtccca gatatttagg ggaattatac ccacaatttt gacatacaaa
    13801 tgtcgctttt ttctttgcga tgacaaacct ctttctatat ctctaactca cactcaatca
    13861 cttggcaaaa atcaatcttc tcatttggca caaactggcg catgagcatt cgatgagcaa
    13921 caactaccac agtctgatgt tctcgatact tagacataca ttctagaaac cgagacttca
    13981 tttccgtagc tgtctcatat tgaataggac tattaggaag caactccccc ttgttttcta
    14041 aaaacagtct tctagctgtt tcaaaatttt ctattcctgt tttatagacc tgccattcat
    14101 gtaataaagg ctctactctt aaaggaagac ccgtagcaca gaccacatac gaagccgttt
    14161 ctaaagctct tgtgactgca gaagatacga ttatttcagc tgacgagagt aaaggatttt
    14221 tgctcaattt ctggacttgc tgccgtccca tctcagacaa gggtgccaaa tctatcccaa
    14281 atcctatata agaacgctcc tctaactcac ggtaatctgg ctccccatga cgtacaaaga
    14341 taatcttcat tctagtgccc tgtcgatcca aatccaccag ttcgaacgcc atcagctgca
    14401 tctccatctg caattaagaa agtagcaaaa acagcctgga caatacgttc cccaacttca
    14461 agaacaacct cttgatctgt gatattcttc atctgcgcaa aaatatgccc ttcatttcca
    14521 ggatttccat aataatcccc atcaatgacc ccaactgagt taattaaaac caagcccttc
    14581 ttacgaggat ttgaagaacg atcatagagg tagagaacct cagtcggctg catataagcc
    14641 ttaacccctg tcggaaccaa gacaatctct cctggcgcaa caactgtacg cacagcaacc
    14701 tttaagtcgt aaccagccgc atgcgctgtc tcacgcttgg gcaataaatt ttcatctgta
    14761 aaactcgaaa ccaattcaaa accacgaatt ttcataattt tctcttttct attatcattt
    14821 attctagatt attctatctt atttattcgg aaaaagcacg aaaaaaagag cacacaattc
    14881 aaatcgctta gggctgctgg attcctcccc tgacccgctt cacgcagaac tgttgctcca
    14941 ctatttatta tatcacattc ctattcattt taaaagcaaa attatttttt ccgtctattt
    15001 ctaaaaaaat cctgcatgat agctgcgcat tcatcttcca aaattcctat ttcaacctcc
    15061 acacgatgat tgagacgctc atctgtcaag atattgtaca aactcccagc agcgccaaat
    15121 ttctggtttt tagccccata gaccacattt ggaatgcggg caagcccaat cgctccacta
    15181 cacatgacac aaggttcaat ggtcacaaaa agtgtgcaat ccagcaagcg ccagctctcc
    15241 tcactcaagt tcgcatcctc tatagccata atttccgcat gcataaccgc tcgctgtaat
    15301 tcctcacgcg cattatgccc acgaccaatg atttccccat ctttgacaat cacacaacca
    15361 attggaattt catcgtgttc aagagcaatc tcagcctctc tcaaagcctc cctcataaag
    15421 acttcttttt cttcaagcgt ataatacatc tcttttctct tttcctactt atcgatttta
    15481 ttattatatc atgaatccca acacaaaaaa agccaccgaa tgcggtgact ctatagggag
    15541 attattatga aaaagaaaag tttaggatat ttgttacaac aagttaggag gtcttcttgt
    15601 aaccgtctat agtatacccg acctatctta aacaaatctt aaaaatctct taggaccaaa
    15661 cactttctaa aatatttgtt tgttcacgac caggacctac tgagaaagta gaaatacgaa
    15721 cgccaaccaa ttcactcaca cgacgaacat agttacgcgc attctcagga agatcttcca
    15781 aattgcgaac tccggtaata tcttctgacc aacctggcaa ctcttcatag ataggcttgc
    15841 aacgtttcaa ttgctcaaga ctagctggat agtagtcaat acgttgaccg tcaagatcat
    15901 aggccacaca gattttcaca gtatccaaac cgctcaaaac atcaatagag ttcaaagaaa
    15961 ggttagtaat accagaaaca cgacggctat gacgcatcac aactgagtca aaccaaccta
    16021 cacgacgtgg acgaccagtt gttgtaccat actcatgacc cacttcacgg atacgttctc
    16081 ccacttcatc aaacaactca gttgggaaag gaccatctcc tacacgactc gtataagctt
    16141 tacatacacc tacaaccttg tcaatcttgc ttggaccgac accagaacca attgtcacac
    16201 caccagctac agggtttgat gacgtaacaa atggataagt accttggtcg atatctagca
    16261 taacaccttg tgcaccttca aaaagcacac gtttgccatt atcaagcgca tcattcaaga
    16321 taacagatgt atctatcacg tatttcttga tttgttgacc atattcgtaa tattcttcaa
    16381 aaatatcatc gaaaacaatc gctttactgt catacaattt ttcaaaaaga cgattctttt
    16441 cagcaaggtt acgttctaaa cgctcacgga aaatatcttt atctaaaaga tctgcaatac
    16501 gaattccaac acgagcagcc ttgtccatat aagctggacc aattccctta attgtcgtac
    16561 caatcttatt gtcgccctta gcttcttctt gcaagcgatc caactcgata tgataaggca
    16621 aaataacatg cgcacgatca gaaatacgca agttatcagt tgttacacct tcctcatgaa
    16681 gatagctcaa ctcttttaca agagatttag gatttacaac cataccattc ccaatgacag
    16741 atattttttc agggaagaaa atcccagatg gaatcaagtg caacttaaat ttcttaccgt
    16801 caatcacaat cgtgtgacca gcattatcac caccttggta acgtgcaatc acttctgcat
    16861 tcgctgaaag gaagtctgta atcttccctt taccttcatc accccattgg gtacctacaa
    16921 caacaactga agtcataatc ttgtctgagc cctcaggctc ttcctttctc acatacatgg
    16981 caggactctc acctgcaatt atatcttaca atttattata ataaaaaatc gtctttttat
    17041 caagaagaaa caatagaaag atttgctatt tccaactatt aaaaaatgat ttagaaaaat
    17101 tactagctat ttactatcat ctttccataa aagagtaaat tagttcggaa atttactaaa
    17161 attacctcaa caagaaataa aaccccgatt cattaccaat ttttcaagat acaaacgata
    17221 agcaacacga taatggtaaa caataaaatc cttacgacaa ccaatgccat atctcactaa
    17281 ataataaatt aaaaatttaa aatgaacatg ttcccagtca aaattatcac caaatgtagg
    17341 accatactct tcttcaatac tatcatagaa attagccatc tgctcataaa ttttttgtaa
    17401 cataatcaaa tactcctttt cttttttata aacttattct aacaaaaaat tttacacatt
    17461 cactatcaat tcctgaattg ttaaaatacc agcctcaaca agataaaaat aggaaaagtt
    17521 gacagaatag aaacaaattt gctacctaaa tttcaaacga ttaaagttct aaaaagaccg
    17581 ccttaaaact tttgggtaaa tcctattaga actataatat ttttatatag gtattatggt
    17641 tctgattttc tagtataaaa aattcaaact agaattcttc ttagaaaagg ccgttttaag
    17701 tgctatcact gttcaaaaat gagggtcgct gaaacttcta tcgtcaagaa gaatcatcaa
    17761 attccttgta tcatcaacca aaagattgct cagaagctaa ttaaaaagac ttctatgacc
    17821 gacattgatc atcagttgtc tatttcaact tcaactgtca ttcgcaagat caatgatttt
    17881 cactttgagc atgatttttc gcgtcttcct gagattatgt cctaggacgt tgaaacagtc
    17941 cggggagtga ctgtttcaat cgggagatgg agatgagctt tattgctcaa gactttgata
    18001 agctcaatat cataactgtt cttgagagca gaacacaagc catcatccga aatcccatga
    18061 atacaaggct atcaagcgat actgaaagct cattcaacaa gatagtcaga aactgagtga
    18121 taaacgattt tatcgcccta cttttcgtat gcacttgact aataaagaaa ttctagataa
    18181 acttttgagc tattccgaag acttgaaaca ccactataat ctctatcagc tcttgctttt
    18241 ccacctcttt ttcagactct gtttaaaacc ttcctcaaag ataaagagaa aatcgtcaac
    18301 gcccttcaat taccttattc caacgccaaa ctggaagcca ccaataatct catcaaactt
    18361 atcaagtaca atgcctttgg ttttaggaac tttgaaaact tcaaaaaaga aaggacgaaa
    18421 tttgtccttt ctagatcttc gctttcttca acccactaca gttgacaaag aaccgaaaaa
    18481 tgtctcgcct ctaatatagt caattgaaac aagaacaaga caaaagagcc tcataaaagg
    18541 tattgcaact tgctaatacc tttttggggt tctttttgat atgaacccat gttttctcaa
    18601 taggattgta ctcaggtgag tagggaggaa gaggtaaaag tttatgccca aactcttcac
    18661 acaagagttc tagcttaccc attctatgga atcttgcatt gtccataata tagtagattg
    18721 aaactagaat agtacacctc tacttctaaa acattgttag aattcgattt tactgtcctg
    18781 atcgatttgt cctattctta tttcatttta ctataacacg aaatagatta ttattacata
    18841 acaaaaaaga ggtctaaacc tcttaactaa attactccgc cagtaggact cgaacctacg
    18901 acatcatgat taacagtcat gcgctactac caactgagct atggcggatt a
//
LOCUS       DAVLZG010000041        18406 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLZG010000041 DAVLZG010000000
VERSION     DAVLZG010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.041"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..730)
                     /gene="lytB"
                     /locus_tag="VYO72_001394"
     CDS             complement(<1..730)
                     /gene="lytB"
                     /locus_tag="VYO72_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1707749.1"
                     /translation="MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANE
                     WVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQD
                     GKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYF
                     KSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHY
                     YYLKSGGYMAANEWIWDKESWFYLK"
     gene            complement(830..1816)
                     /locus_tag="VYO72_001395"
     CDS             complement(830..1816)
                     /locus_tag="VYO72_001395"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1707750.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGAAAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1779..2579)
                     /locus_tag="VYO72_001396"
     CDS             complement(1779..2579)
                     /locus_tag="VYO72_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1707751.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2829..3209)
                     /locus_tag="VYO72_001397"
     CDS             complement(2829..3209)
                     /locus_tag="VYO72_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1707752.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3267..3626)
                     /gene="rplT"
                     /locus_tag="VYO72_001398"
     CDS             complement(3267..3626)
                     /gene="rplT"
                     /locus_tag="VYO72_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1707753.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3678..3878)
                     /gene="rpmI"
                     /locus_tag="VYO72_001399"
     CDS             complement(3678..3878)
                     /gene="rpmI"
                     /locus_tag="VYO72_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1707754.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3911..4441)
                     /gene="infC"
                     /locus_tag="VYO72_001400"
     CDS             complement(3911..4441)
                     /gene="infC"
                     /locus_tag="VYO72_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1707755.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4457..4588)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4748..5929)
                     /locus_tag="VYO72_001401"
     CDS             complement(4748..5929)
                     /locus_tag="VYO72_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707756.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDISSEEYQFAKNNLDVQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQAMYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(5933..6520)
                     /locus_tag="VYO72_001402"
     CDS             complement(5933..6520)
                     /locus_tag="VYO72_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707757.1"
                     /translation="MLRLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6552..6776)
                     /locus_tag="VYO72_001403"
     CDS             complement(6552..6776)
                     /locus_tag="VYO72_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707758.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYYSYSEYPVGSGWNYARYEVINYYTGGY"
     gene            complement(6918..9158)
                     /locus_tag="VYO72_001404"
     CDS             complement(6918..9158)
                     /locus_tag="VYO72_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1707759.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKAAQHGSKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            complement(9142..9792)
                     /locus_tag="VYO72_001405"
     CDS             complement(9142..9792)
                     /locus_tag="VYO72_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1707760.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(9860..10429)
                     /locus_tag="VYO72_001406"
     CDS             complement(9860..10429)
                     /locus_tag="VYO72_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707761.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLVNPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10606..11031
                     /locus_tag="VYO72_001407"
     CDS             10606..11031
                     /locus_tag="VYO72_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV1707762.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            11032..11445
                     /locus_tag="VYO72_001408"
     CDS             11032..11445
                     /locus_tag="VYO72_001408"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV1707763.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            11391..11717
                     /locus_tag="VYO72_001409"
     CDS             11391..11717
                     /locus_tag="VYO72_001409"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707764.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(12084..12343)
                     /locus_tag="VYO72_001410"
                     /pseudo
     CDS             complement(12084..12343)
                     /locus_tag="VYO72_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12346..12846)
                     /locus_tag="VYO72_001411"
     CDS             complement(12346..12846)
                     /locus_tag="VYO72_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707765.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGFFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            12882..13061
                     /locus_tag="VYO72_001412"
     CDS             12882..13061
                     /locus_tag="VYO72_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707766.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(13039..14007)
                     /locus_tag="VYO72_001413"
     CDS             complement(13039..14007)
                     /locus_tag="VYO72_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1707767.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14093..14308)
                     /locus_tag="VYO72_001414"
     CDS             complement(14093..14308)
                     /locus_tag="VYO72_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1707768.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            complement(14317..15171)
                     /gene="cvfB"
                     /locus_tag="VYO72_001415"
     CDS             complement(14317..15171)
                     /gene="cvfB"
                     /locus_tag="VYO72_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1707769.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15231..15788)
                     /gene="frr"
                     /locus_tag="VYO72_001416"
     CDS             complement(15231..15788)
                     /gene="frr"
                     /locus_tag="VYO72_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1707770.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15797..16534)
                     /locus_tag="VYO72_001417"
     CDS             complement(15797..16534)
                     /locus_tag="VYO72_001417"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1707771.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16618..17952)
                     /gene="trmFO"
                     /locus_tag="VYO72_001418"
     CDS             complement(16618..17952)
                     /gene="trmFO"
                     /locus_tag="VYO72_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1707772.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18197..18391)
                     /locus_tag="VYO72_001419"
     CDS             complement(18197..18391)
                     /locus_tag="VYO72_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1707773.1"
                     /translation="MEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
BASE COUNT         5283 a         4181 c         3414 g         5528 t
ORIGIN      
        1 atttgagata aaaccaagat tccttatccc aaatccattc attggctgcc atgtagccac
       61 cggattttag ataataatag tgaccattct cgaaaatcca ttctttatca gcatagtttc
      121 cattttcttt gatgtaaaac caagattggt attgtttgtc aaaaagccaa ccttgctgta
      181 ctttggcacc actagcattc acataagctt gattaatcca ctgacttgtc agtagataac
      241 caccggattt gaaataatag tccttccctt taatttggag ccattctttc tctgcgtgct
      301 gtccatctgc tttgatataa aaccaagcat cgtattgaga atcatagacc cagtcttcta
      361 ttactttggc acctgttgca ccaacatagg aagttcctac ccaagcattt cttttcatct
      421 ttccatcttg gtcaagataa taaaaggctc ccttgtcttc tacccattct gatttggcca
      481 tatagccacc agatttgagg taaaaatagt cgtcaccttg ctttagccac tcattttcag
      541 catagttagc atctgctttt atatagaacc aagattgata atgagtatca aaaacccact
      601 cattcgctgc ttgactgcca tcttctttca gatactgttt tccttgccaa gtaccatcac
      661 tagccattgc accctctgga ctagctaaga aaaatagcag agctaaaaaa ataaatctta
      721 ctttcttcat taaccttctt cctctgttct tatttatatt tattgtacca aaattctcct
      781 aaattcatat tacaaactaa taaaaaatca agaacagatt gattgcagtt tacctcagag
      841 actcttttac ttcctgacgg agttcttcca gactgctaat accgtattta tccatgactt
      901 ttggtaaatt ttcgatgatg tcagggcagg cataaggatt ggtaaagtta gctgttccaa
      961 ctccgatagc agctgcccca gccagataca tttctagggc agcttcagcc gaatccactc
     1021 cccccattcc aatgataggc aggtctgttg tttgggctac ttggcggatg agtttgaggg
     1081 ctactggaaa gactgctgga cctgacattc cacctgttcc attggccaag attggttttc
     1141 tggttttgag gtcaaagcgc attccaacca gagtattgat catggtcaag ccacttgctc
     1201 ccgcatcttc tgcagctttt gcgacagtaa cgatatcggt cacactcggg gttaatttga
     1261 cataaactgg cacttctgag gcttccacag ctgctttcac cacatcataa gccaaatctg
     1321 gatcttgacc aatcaaaagt ccatgattac agtggtcaac attgggacaa gaaatattga
     1381 gctcgatagc ttttacatta gttgccttgg aaatcccatg agaaacagct gcatactctt
     1441 gttttgaaaa accagctaca ttggcaataa taggaagatt tggatattct ctttccagcc
     1501 aaggtagctt ttcagccaaa acaacctcta aaccaggatt ttgcaagcca attgcattga
     1561 gcataccagc aggcgtctct gctactcttg gagttgggtt cccaaaacgt ggttcaaggg
     1621 ttgtcgcctt gatcataata gaacctaaaa ggtttaaatc atagtacttg gcatactctt
     1681 gtccaaagcc aaaacagcct gatgctggaa taatcggatt tttcaaatcc aaaccaggta
     1741 gagacacttg taatcgattt gtagtcataa ttttctcctt ataatacaac tgttcctgtg
     1801 cggaaaacag gaccatcttc acagacgcgt tggctgaccg tctcgctttc tggtactttt
     1861 agaacacagg catagcaagc tcccatccca caagccatac gagattccag agataaatag
     1921 gctcttgggt gatcatcaaa ggtttgattg atatacttca tcattcctgg agccccacac
     1981 gagtaaacag catcaaactg actatctaaa tcattgataa caacggaaac atttcccttg
     2041 atgccataag aaccatcatc tgtcgttaca aagacctgac catactgagc caattccgtt
     2101 ttcaaaataa cagcatcctt attagcaaaa ccgaggactg tcactacttt cactccacgt
     2161 tcatgcaatt ccttggccac ctcaagcaag ggtggaacac caatcccacc accaacaagg
     2221 agaacctgat tctgctcatc aaggtcagac aagtcaaaac catttccctg aggccccatc
     2281 acatcaagag tgtctccctg acttaaggtt gaaaaaattg cagtcccagc tccctcaatc
     2341 cgataaatga ggtgacactg cttgtttgcc ttgtcaatag acgaaattga aataggacga
     2401 cgtaagagat gggcatcgtc tggtacacgc agatgaagaa attggcctgc tcgcatggct
     2461 tcaaccattt ctccttctag gactaattca aagattgctg gcgcgatttc ctcttgtgca
     2521 accaccttca tggtttccaa ccgaatgaca cccaaacgct tcttacatgt gagattcata
     2581 acttttcctc cttaaatttt aaggggacca gataaagaaa agaccttgct agtgcaaggc
     2641 ctcagttaaa atcgtacaac acaagagagc acactcaaaa ggtctcctct agaaaattgc
     2701 actattcttt tatctgacac cttgtgagtc tctctggact ccccttaaag gttgaatttt
     2761 tattagtata ctctttcagc taaaaaaagt caagtagaaa acgaatattc tacttaactt
     2821 gcacgaaatt atttttcacg aatgacttcg accttatatc catcagggtc tttgacaaag
     2881 taatagtttg gtgtagttcc tggtagacca tttggctcag tcacttcata gccttttgca
     2941 ctgtgttctt gatgaagtgc ctcaagatca ggtgtactga gggcgatatg ggcaaaccca
     3001 tcaccaacca catacggacc gtgatcgtag ttataagtca actccaactc ataatcatca
     3061 ccctcaagac ctagatagac aatcgtgaag gcatggtctg gaaaatctct gcgacgcaat
     3121 tctttaaaac caaaagcatc ttgataaaat gcgattgatt tttcaagatt ttctactcgt
     3181 aagcaagtgt gtagcatttt tgaagccata tctttctcct ttatttttaa aaagactgga
     3241 caatcctgtt ccagtctcat cagttgttat ttaccaagtt ttgctttagc tgcatctgca
     3301 agagctgtga aagctactgc atcgttaaca gccaagtcag caagcatttt acggttaact
     3361 tcaatctcag ccaatttcaa accatgcatc aattgtgagt atgaaagtcc gttcatacga
     3421 gctgccgcat tgatacgagt aatccacaat ttgcggaagt cacgtttttt ctgacgacgg
     3481 tcacggtatg catagtagta agagttcatt acttgttctt ttgcagtacg gaacaagatg
     3541 tgtttagctc catagtaacc ttttgctaat ttaagaatac gtttacgacg tttgcgtgat
     3601 acaacgccac ctttaacacg tgccatgttt tatttcctcc aaatatttcc tagaattgtt
     3661 tacttacagt caagctatta tttcaagcga gtaagcattg ctttgatacg tttgtaatct
     3721 cctgaatgca ccatagatgc tttacgaaga tgacgacgtt gtttcttagt ttttccgtgg
     3781 aaacggtgag aagtgtaagc acggaaacgt ttaagtccac cagaacctgt acgtttgaaa
     3841 cgtttagctg atgcgcggtg tgttttttgt tttggcatga ttttttctcc tttatttaac
     3901 tttctgacaa ttattttttg tcagtcgctg gcgccaattg catgaacatt tgacgtccat
     3961 ccattttagc acgttgttcg atgatggcaa tatcttgagt tgcttcagca aactcggcta
     4021 aaacttttgc accaatctct ttgtgggtaa tcatacgacc cttaaagcga atagatacct
     4081 taactttatt tcctttttca aggaacttac gtgcattgcg aagttttgta tcaaagtcac
     4141 ccttgtcaat tgttggactt agacgaactt ctttcacagt aacaacgctt tgttttttac
     4201 gttgttcttt ttgcttcttc tggtactcaa atttgaactt accgtagtcc ataatttttg
     4261 caacaggcgg tttggcttgg ggttgaatca atactaggtc aacattagcg ttatcagcca
     4321 aagcttgcgc ttcactgagt ggcttgatgc ctagctgttc tccctcaaga ccaatcaagc
     4381 gaacttcacg tacacgaatc tcatcattga tgaataagtc ttgctttgct atggttttca
     4441 cctcttttgt tttattagag aaaaacaata gcggactcgt aaatatacaa gcccgcacgt
     4501 tatgatagcg tttcttcgaa acttttcatc cgtagggcca ggcaacttaa tgtcacaagg
     4561 cgagaagctc tcacttctgc ttttctcaac ttttatatga taccaagttt tctagctctt
     4621 gtcaagataa aaagttattt tttgaaaagt ttgtgtttgt attttggttt ggttttcgaa
     4681 tcaaaaagag agaaccaagt tgattctctc cctatgttag tttttcttta gcttccctat
     4741 aggaaaacta aactttaaaa acttcctttt tacgtgaact tccccatctt tcgataaata
     4801 gaatccccac taacaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4861 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4921 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaatggtt tggatgccaa
     4981 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5041 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5101 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5161 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5221 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5281 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5341 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5401 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5461 gtgcttttat gttcaaggga tacatggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5521 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5581 cttgccactg cagatagtag gcctctttcc agcgcccttc ttttaataaa gtcagaattt
     5641 ctgtctttcg cttcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5701 cctccgagct gatatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5761 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5821 tatttaaata aaaggtaaca ccgagtacag atacaaataa agctaagaca atccagttta
     5881 agcggctttt gaaaactttt ttcaataaaa atagactaac atctttcata aactaaacct
     5941 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6001 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6061 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6121 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6181 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6241 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6301 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6361 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6421 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6481 cttgtcgcgt ttttagggta acatgagtaa gccttaacat atccagccct ccttttctca
     6541 ctctttaagg attaataacc tccagtatag tagtttatga cctcataacg agcgtagttc
     6601 cagccagaac caactggata ctcagaatag ctgtaataac gagaccatga cggaatccaa
     6661 gcatactgat ggtcgtgata gttggtacta tattcccaaa ccgtattcca atcatacttg
     6721 taacttttag tgactgtcac agcagatata ctggactgaa aaagaccaat aatcataaac
     6781 taactaatta aacgattttt gctaattttt aatgatttta tatcctcagt attgaatacg
     6841 ttttcattat accattttta tcattattat gcaacaaatt tttagtttat ttcactaatc
     6901 tacaacattt atccttccta tcgaacactt tcgattttcc aactattcca acctttaaac
     6961 cgtatagctc cttgctggtc agttcggtaa actttgctat tgataccttc cagtcgtgtc
     7021 aatgtttcct gatgggggag tttcattcga ttgctctttc caactgagat aagagtaagc
     7081 tctggtttga gtttttctag aaaggctgga cttgatgact ttttagagcc atgttgggca
     7141 gctttcaaaa catttacttt caagtctgga tagtgcttca gcaagtcctt ctctcctttc
     7201 tcctccaaat ttcccgtgaa gagaaattgc ttatccaaga atttcccata cagaactagg
     7261 gtatcatcgt gtcctccatc tcccattttc cttggagata gaacttctaa ctgacttcca
     7321 aaaatgggca agttctcccc tactgtcata ctacgcacct ttgtttgagt cgcctgtagt
     7381 tctaccacaa attgcttctg cttcaaactg ccttttgata ctaaaatctc ccctacatgg
     7441 aaagccttgg tcacctctaa caaatctccg acatgttcct tgtccgtatt tgtcaaaatc
     7501 agctggtcaa tcttagctac tcctcgactt ttaagatagg gtatcaagct tctctgtgca
     7561 ttgctggtcg tcatcttttc ttgccatttt tcgattttct tataagattc tgccttacca
     7621 cctacatcta tgagaatggt tttcccagtt acatcccgta ggaaaatact ttctccttgc
     7681 cccacatcca gcatggtgat ttcattttcc agtggatgct tggtcaggag aaagagccct
     7741 gtaatcaata agcacaatac cgttagcttt ttaatgtttt ttctcaaatc atagaccaaa
     7801 gccaaggaaa ttaacaatag gattaaaaac catgcattgg gttgtccaaa gaccagaggt
     7861 ctacttgtca cctgtgacac caagcgaata atgccctcca accattcaaa gataaagttc
     7921 agctgaatga ctggatagag aaaggaaagg acaaataaaa tagacaagag cggtaagaag
     7981 gtcaagtcaa atagaaagga aaagacaaag gtcaaaagga tagaccaagg ttgaaattcc
     8041 gcaaaataga aggatagaat gggcaatatg cccaaggaga tgactagact ttcactagta
     8101 acagccttga gcccctcccc ttctttgctg gtcatggtca ggataaaagc ataagcgcag
     8161 gacaagactc ctcctgctgt caagaaaaag tttggcatga caataaagag gacaagcacc
     8221 gtcaaggcaa aattatccaa gcccttaacc ccatgttgag ccagtagctt ttgcaagaga
     8281 ctgcgaataa ccgatgctga aaagccagtt agtcccgcat agataaggga aaagggataa
     8341 gtcagccatt tcaacttttc ttgggtcaag cccaatcgca agagaagttt cttaaatcca
     8401 ttcatgaaaa aacctacctg cataccagat agagcaaaga ggtggataat tcctagactg
     8461 gaataaagct cattcatctc ctcaaagtcg gtgtccagat gtcccagcaa gagtcctgtc
     8521 atgtaattgc gcatagggtc tggaaagtgc gtcttaatcc aaaccacagc ctttcgacgt
     8581 aaactggaca agttttctcc tatatcccaa ctgccaatct tttgaagtga ctggattgtt
     8641 ttgatattga gagtctggta aattccctga gtcttcagat aggcttggta attaaagcca
     8701 ccaaaatttc tctgcccttc tggctccgaa agcttccctt ctagtcctat ctcatgcagg
     8761 tcggttaaag cttgaaaggc ttctttctcc tcctcggact ggagtttata atagacttgg
     8821 aaagcacgac cgttagactt gccacgaaag gatagactat caccattaac cttaatagta
     8881 tcaggcaaaa tccgtaccct ttcaacagaa tccgccagat tttgactcgc ttgactctgt
     8941 tgccaatttt gaaaaacaaa ccaaaatcca aagattccgc aaattattag aactttacca
     9001 gcagatttcc acggaaattg gataaagaga cagactagca gaaaaacaaa gcccaacaaa
     9061 gcaagataag atgctgagaa aatagcgtaa taaagccaaa gtaatagaaa actcaggtaa
     9121 attaggggaa tagagaaatt cttaatccac tgtaacatag tctttaagct tttctattgt
     9181 tttgccacca atgccagaga ccttcttgag ctcgtctact gacttgaact tgccatttgc
     9241 ctcacgatgg tcgataatgt cctgagctcg ttttcctccc agtcccttga cctgcttgag
     9301 ttcttccaga ctggccttgt tgagattgac cttcttttcc ttgcttgttg aagaagctgt
     9361 ccccgaacca gtctgttgac taactgcttc ttctccctta gtaggaacgt aaaccagagc
     9421 ctcatcacta actttctgag ctagattgag cgacttgctg tctgcttgct ctgtcaagcc
     9481 accagccttc tgaacagcat cattgactcg actacctaca ggcaagtcat aaatccctgg
     9541 cgatttgaca gcacctttga catctactgt gattagatct tgttcaactg gttcttcctt
     9601 ctcttccttg ttcacttcct tttcggatac caaatccttg gaaacagctg caacttcaac
     9661 ctgcaaattc gtttctttga caggtgtttg tggagctggc tttagcagga aaaatccgcc
     9721 tacaagcaag cccagaccag tacagatgac gatgatttta tactctttga ttttctcgat
     9781 aattgcttcc atattttctc ctctcttaga ttattcgtaa gaggaagaaa aaacagtcga
     9841 aaaatttctt ttcaactgct tatttatttg caaaatagtc ttccttggtc aagacataat
     9901 gaactcttgt cacgattcgg cctttttcat gctggtccat acaagcatat ggttctgcat
     9961 gggaaaaacg catgcctgat ttctccatga cctttcctga cgcgggatta gccttatcgt
    10021 gaagggcagt caacttattc atccctatct tctcaaaagc tagctcaatc acagcacgat
    10081 tggcttctgt cgttaatcct tgattccaat actttttatt gataatgtag ccaatagctg
    10141 ccttcttaag aacagaatca atcttgtgca agtcaatggt tccaataaac tgaccattgc
    10201 tttttagttc tattccccaa cgtcccaagg gattaaccaa atagaactga gcaatgttat
    10261 tcttggtttc ttccaagctt tgattggttg gaaaagtgta acgtgtatta cccttgtccg
    10321 aggcatagtc aaacattgct tccgcatcat ccaaagttac aggtctaagc aataaacgct
    10381 ccgtttctat agacggatac tgggcaagtt ttacaaaaat tgattccata cttttccctc
    10441 cattagagct tgattttcac tagtctagca taaaaaaatt gggatgacaa gtttttcttg
    10501 atttttgaag cggtttcata tacaatgaaa ccgtcacatt tttgatttat gaactggaat
    10561 gtgacaacca aaacaagacc gtcaattgaa aggtaggtta tctcaatgtt aatcggaatc
    10621 ccaaaagaaa ttaaaaataa cgaaaaccgt gtcgccctca cacctgcagg tgttcatagc
    10681 ttagttagtc gtggtcatcg tgtccttatc gaaacaaatg ctggtctcgg ttctggcttt
    10741 actgatgctg actatcaaaa gcaaggagct gagattgtcg ctactgctgg tgaagcttgg
    10801 gcagcagagt tggttgtgaa agtaaaagaa cctttaagtt ctgaatacgg ttacttgcgc
    10861 gacgttcttc ttctcttcac ctacttgcac atggccgctg ctccagaatt agcagatgct
    10921 atgttagcag caaaaacaac aggaattgcc tatgaaactg ttcgtgacaa tcaaggacaa
    10981 ctaccgctcc tcgttcctat gagtgaggtt gcaggtcgta tggctgttta aatcggagct
    11041 cacttcctta ctaagcaagc tggtggctct ggtgttctac ctggtggtgt accaggtgtt
    11101 ccaaaaggaa aagtaactat catcggtgat ggtgtcgtcg gtacacatgc tgcccgcatc
    11161 gcccttggtc ttggtgctca agtgactatt ttagatatta gtgccaagcg tctctcagtt
    11221 ctagaagaag tctttggaag tcaaattcaa actcttatat ctaattcatt caacattgaa
    11281 gcaagtatga gagatgctga tgtggtgatt ggagccattc tcatccctgg tgcaaaagca
    11341 ccggaattgg tgacagatga gatggtcaaa caaatgcgtc caggctctgt atcgttgacg
    11401 ttgctgttga ccaaggtggc gttatcgaaa cagctgaccg tgtgacaacg cacgatgaac
    11461 ccgtctatga aaaacacggt gttctccact atgccgttgc caatatccct ggtgcggttg
    11521 ctcgcacttc aaccatcgcc ctaaccaatg tcactcttcc ttatatcgaa gctttggctg
    11581 gcaaaggatt cgcacaagca atctctgaag atgaaggctt gcgtcaaggt gtgaccactt
    11641 atcaaggtta cttgactagc ctaccagttg ctcaaggact taatcgtgac tacactgata
    11701 tcaatgattt agtataaatt ttgaaaagaa aagggtgact tcgcaagtcc tacccactgt
    11761 gctttgtgtc atcagctatt acatcgttgg tttattgtac tgtatacttt gcaactggag
    11821 actttcgttc cagactcaat tgtgcataag aaactctaaa ttgaataaag tcaacagagt
    11881 ttcgcccaac cacttcgtct tgtaatgaca attatataaa ccaaaggaag ctgagctctt
    11941 tagtcccagc ttctttttat atataaaatt ttacccgtgc aaagacaggg ccttagcaga
    12001 cttctttttt acttcgttca cccttgcttt ttctttttag gtttgggcgt tggcagttgg
    12061 ttatacatag ctaaaatcag gtcttataga aacatcttat tatcaagttc ttccactcaa
    12121 atcatttctt tggcaccttt gtatggaaac tcaaaagaag attggtcaat cttatctaag
    12181 actgcttgca cgggtttaac taaaagcgat cgtcataaat gccgccaata atcttgccgc
    12241 ggaagtaaag aatatactcc cccatcatgg aacggtaagt cacatcatct aatcctgata
    12301 attgttccaa aacaaattcc aaatagttct tacttgatgc catttctaat cttctaggct
    12361 ctgttcaacg ataacaaccg tatagagttc ttgcttaacc tcgcatccaa ttgatttaaa
    12421 gccctgcttt tcccaaaaat gctgagattg cggatttccc ttaacataag ccaaacgtgc
    12481 ctttcgaaag ttcttagcaa aataagctag tgcttctgtc acaatatgac taccaatccc
    12541 tttcctctga taggcttgat caaccataaa aaaaccaata aaaacagtct cctcatcagg
    12601 atatgcatag acaaaatcca taacagccac aaggtcagat ccattccaaa atccaacaaa
    12661 aaacttatca gccttagctt taccttcagg tagacaaagc atgtcctctt ttacagttgc
    12721 aaaatttggc tctggtggac aatgctgaaa atacagagga ttactttcat ataaagataa
    12781 aatacttgga atatcctttt cagttagtat cctacaactg taatacttag atagttggtc
    12841 aatcatcttt tcaaattcct actttcttgt gccctgtgat tatgacacag gaagatgcac
    12901 tgatcgtcat cagtcacata aaagttcttt ccatcgtgcc taatcgttgt ctcagacctt
    12961 tggataaaac ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc
    13021 aggcgaactt cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat
    13081 aatctgagcg acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat
    13141 ctgatggatg ttcttgagtt tctcttgagc atcaatcaaa ccggacttga cattacgtgg
    13201 caggtcaatc tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt
    13261 caagaacatc ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc
    13321 atcatccaag gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc
    13381 catgagacga gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg
    13441 aaggtaagga tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc
    13501 ttccaccgct ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac
    13561 tgccaaggtc actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac
    13621 atcatgctgt ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg
    13681 cttcccagta ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc
    13741 atcatttttg accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg
    13801 atttaccaag accatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc
    13861 tcccaaaacc tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat
    13921 caaacgaaga tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag
    13981 ttgaatgtct attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt
    14041 tattatagca gagggatgga gaaattacta gcccaaacct agtgaataaa tgctagtgtt
    14101 ctaagtattc ttgccagata gcgtcaaagt ctcctaggtt aaaagagaaa ctggcatgct
    14161 cctccaaaaa gcgactgacc tcatcaaaat catctgtgtg ttttggaaaa gctgcctctt
    14221 caaaagcgag gtctgccaaa attgctttgg gactgttact tttaggattg cgctcggtca
    14281 tgagccaagt gtaaaatgat tttctcataa gcctccctaa atcaactctg tcccaaactg
    14341 gtcctgcttg attttaccag ccttcataag accacctaag gctttcttga actgaccttt
    14401 agaaatgcca aaggttgcct tgatgtcgtc tggagatgac ttatcattta aggtcatgaa
    14461 accgccatta ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa
    14521 ggagcgtggt ttgagggaga ggttcagagt gcggtccact tcacggaaac caataacgcg
    14581 cgcatctaat acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc
    14641 aagcatatta ttttctggta ggtaaacaaa agttcctgac agcttgagac ggtaaacaat
    14701 ggctggccag ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc
    14761 ttcttgataa gccaagaggc cccagatacg gtctttctta tccacttcaa gacggatgta
    14821 gagttggtcg cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac
    14881 aacgatttcc ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc
    14941 tgtgacacgt ccccaaccaa attggtcctg agtggcagtc acttctaagg ttgtcaggcg
    15001 gagtttttgc ttcatatccg tgtatgcaaa acccttgacc gtatccccta ctgtatgttg
    15061 gccttcttcc ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc
    15121 gttttcatcg atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc
    15181 tttcgaataa aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc
    15241 aaaagttctt tctctttgtt agcagtcatg tcgtcgatgt gtttaacagc atcgtctgtt
    15301 actttttgaa tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt
    15361 tcttgtttct tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca
    15421 ttttcgccga ccttcttcac ttctttagca aggtcacgac gagtttcttc tgtaagagct
    15481 gggataacca agcgaatcac agaaccgtca ttagccggtg tgataccaag atcagaagcg
    15541 ttcaaggcac gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca
    15601 cgcgcttctg gaatcgtaat tgaagcgatt tggttaagag gagtttcgac tccatagtat
    15661 tctacatgta cacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat
    15721 tcacgagcaa gtgattggtg agactgggtc attctctctt tagctttttc aataattacg
    15781 ttagccatat tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat
    15841 tttcaccaaa tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt
    15901 caatgtcgtt gtccattgag agggttgagg ctgttgagtc catgatacga agacctttgt
    15961 tgataacatc acggtgggtc aattcttcaa acttaacggc tgtcttgtcc ttcttaggat
    16021 cggcattgta cacaccatcg acgccatttt tagccatgag gatggcatct gcttcgattt
    16081 cagctgcacg aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac
    16141 caaagataac gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct
    16201 ctgccacttg ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca
    16261 atgaatctgc catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct
    16321 gaacacggtc catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa
    16381 taacaagggc aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt
    16441 gaactgtttg gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact
    16501 tgattaaaat acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc
    16561 tattttatca caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta
    16621 gacagtcaaa aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc
    16681 cttcttatca cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat
    16741 tggttggaaa tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt
    16801 cgtctcgggg aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc
    16861 aactaagccc gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa
    16921 gaagagattt ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat
    16981 gtaagaattg cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat
    17041 catttggaag acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt
    17101 gtataggcta ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa
    17161 ttctccatca cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg
    17221 gccataaagc atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc
    17281 aaagtacttt tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc
    17341 atggaaatcc ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt
    17401 atcataacga gatttgagat agaccttact catatcgata gtgttgacat cgataatagg
    17461 cgctgctgca tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc
    17521 cagggcatcg ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc
    17581 tgtaatttca tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat
    17641 ttgagagaaa ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc
    17701 agcagattcc aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc
    17761 atttgtcaaa gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt
    17821 tttatgctgg ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg
    17881 ctctgcgatt tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata
    17941 agattgagac acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa
    18001 agccaatcag acttacaagc tttcgagttt cttggctcag gctgaaaaag tccacaggac
    18061 tttttcactc ccacaaatct ttctattttt tcttctacta gtataacaaa aaaagggaag
    18121 aaggcaaact tccctgttta gtcattttct tgatgtaaag agatagtgag tattccagtt
    18181 aagaatcaat tatatgctac tctataaaat cttttccaca taacggatcg atagggactg
    18241 ttattctatc tcttgctata accgtattat ctaaaacagc ataacattca acatagtgat
    18301 ctcctttaaa ctgtgaatct tcgtgatatt ttattttacc tgaaaaaata gcaccacgct
    18361 cacaatttct tctaatagcc tcagcttcaa tatttcttac tttcca
//
LOCUS       DAVLZG010000042        18185 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLZG010000042 DAVLZG010000000
VERSION     DAVLZG010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.042"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(92..169)
                     /locus_tag="VYO72_001420"
                     /pseudo
     CDS             complement(92..169)
                     /locus_tag="VYO72_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            240..854
                     /locus_tag="VYO72_001421"
     CDS             240..854
                     /locus_tag="VYO72_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1707774.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGNAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAVLRLVF"
     gene            958..1788
                     /locus_tag="VYO72_001422"
     CDS             958..1788
                     /locus_tag="VYO72_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707775.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1829..1906
                     /locus_tag="VYO72_001423"
                     /pseudo
     CDS             1829..1906
                     /locus_tag="VYO72_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            2010..2840
                     /locus_tag="VYO72_001424"
     CDS             2010..2840
                     /locus_tag="VYO72_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707776.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2994..3848
                     /locus_tag="VYO72_001425"
     CDS             2994..3848
                     /locus_tag="VYO72_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1707777.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3948..5321
                     /locus_tag="VYO72_001426"
     CDS             3948..5321
                     /locus_tag="VYO72_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1707778.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAYFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQRHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            5314..6375
                     /locus_tag="VYO72_001427"
     CDS             5314..6375
                     /locus_tag="VYO72_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1707779.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEESSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            6377..7069
                     /locus_tag="VYO72_001428"
     CDS             6377..7069
                     /locus_tag="VYO72_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707780.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(7099..7668)
                     /locus_tag="VYO72_001429"
     CDS             complement(7099..7668)
                     /locus_tag="VYO72_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1707781.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7803..8417
                     /locus_tag="VYO72_001430"
     CDS             7803..8417
                     /locus_tag="VYO72_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1707782.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFISSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            8419..10065
                     /locus_tag="VYO72_001431"
     CDS             8419..10065
                     /locus_tag="VYO72_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1707783.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKVSPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            10077..11363
                     /locus_tag="VYO72_001432"
     CDS             10077..11363
                     /locus_tag="VYO72_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707784.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            11424..11957
                     /locus_tag="VYO72_001433"
     CDS             11424..11957
                     /locus_tag="VYO72_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707785.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            12035..12505
                     /gene="nrdI"
                     /locus_tag="VYO72_001434"
     CDS             12035..12505
                     /gene="nrdI"
                     /locus_tag="VYO72_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1707786.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12798..14060)
                     /locus_tag="VYO72_001435"
     CDS             complement(12798..14060)
                     /locus_tag="VYO72_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1707787.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(14370..14828)
                     /locus_tag="VYO72_001436"
     CDS             complement(14370..14828)
                     /locus_tag="VYO72_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1707788.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14825..15265)
                     /locus_tag="VYO72_001437"
     CDS             complement(14825..15265)
                     /locus_tag="VYO72_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1707789.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15698..16564
                     /locus_tag="VYO72_001438"
     CDS             15698..16564
                     /locus_tag="VYO72_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707790.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16901..17458
                     /locus_tag="VYO72_001439"
     CDS             16901..17458
                     /locus_tag="VYO72_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEV1707791.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            17679..>18185
                     /locus_tag="VYO72_001440"
     CDS             17679..>18185
                     /locus_tag="VYO72_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV1707792.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGSA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPL"
BASE COUNT         5604 a         3211 c         4018 g         5352 t
ORIGIN      
        1 cgtcagttct atccacaacc tcaaaacggt gttttgagct gacttcgtca gttctatcca
       61 caacctcaaa acagtgtttt gagctgactt catcagttct atctgcaacc tcaaaacagt
      121 gttttgagca acctgcggct agtttcctag tttgctcttt gattttcatt gagtattatt
      181 aagacaatat gaggagaaag atgaaagaaa aaggatttta ggagggggcg caggcagcca
      241 tgccaacggc tcttggctat gtcagtatcg gcctggcctg tgggactatc ggtgcgccct
      301 atgtgacacc tgttgagatg ggcttgatga gtctctttgt ttatgctggg aatgcccagt
      361 ttgccatgtt ggcactgatt gtggttcaag ctcctgtggc agctattgct atgacggttt
      421 ttctaatcaa cttgcgtctc tttttgttga gtttacacgc atcgacttat ttccgtcata
      481 ccagtctttg gtacaatatc ggtatgtcta gtatcttgac agatgagacc tatggcgttt
      541 tgatgggtga attggcccat acagacaagg taaatcctat gtggatgcac ggaaacaatc
      601 ttaacagcta tgtggcttgg tttgtgggga cagtagtcgg aacggctctg ggtggcctgc
      661 taccaaatcc agaaatcttt gccttgattc tttcaagcgt agtgacaggt aaggttggga
      721 gccttcctca aattaaatgg ctagacttct tagccgtctt tccaacagct tgggtagcct
      781 ttcgctaccg caatctagtc ggaacagttc tctttggagt agtcttgatt gccgtcttgc
      841 gtttggtctt ttaaatcagc cataaagaaa acctatcaca gatatatata tcatataatg
      901 gtgtaaatga tttttttctg ttaagactat aaggtattct attttggagg aaatgacatg
      961 aaaaaaatcg ttaaatactc atctcttgct gccctagggc ttgttgctgc aggtgtgcta
     1021 gcagcttgct caggtggtgc taagaaagaa ggacaagcag ctagcaagaa agaaattatt
     1081 gttgcaacta attcttcacc aaaaccattc aactatgaag aaaatggcga attgactggt
     1141 tacgagattg aagtcgttcg cgctatcttt aaagactctg acaagtatga tgtcaagttt
     1201 gagaagacag agtggtcagg tgtctttgcg ggtcttgacg ctgaccgtta ccaaatggct
     1261 gttaacaaca tcagctacac taaagaacgt gcggagaaat acctttatgc agccccaact
     1321 gttaaagacc ctaacgttct tgtagtcaag aaagacgatt ctagcatcaa atcgcttgat
     1381 gatgttggtg gaaaatcaac agaagttgtt caaggaacaa catctgctaa acagttagaa
     1441 gactacaaca aacaacactc agataatcca actatcctta actatactaa agcaaactta
     1501 caacaaatca tgggccactt gagcgatggt cagtttgact acaagatttt tgataaaatc
     1561 actgttgaaa cagtcatcaa gaaccaaggt ttggacaact tgaaagtcat cgaacttcca
     1621 agcgaccaac aaccttacgt ttacccactt cttgctaaag gtcaagatga gttgaaaaca
     1681 tttgtagaca aacgtatcca agaactctac aaagacggaa ctcttgaaaa attgtctaaa
     1741 caattcttcg gagacactta cctaccggca gaagctgata ttaaataatt tcttgaaatc
     1801 atccattctg agtaagatgg gtgatttttc agttcgctac cgcaatctag tcggaacagt
     1861 tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta cccataaaaa
     1921 aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt
     1981 ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg
     2041 ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg ctcagggggt gctaagaaag
     2101 aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaggccat
     2161 ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt cgcgctatct
     2221 ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca ggtgtctttg
     2281 ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac
     2341 gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtcgtga
     2401 agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg
     2461 ttcaagccac tacatcagct aagcagttag aagcatacaa tgctgaacac acggacaacc
     2521 caactatcct taactatact aaggcagact tccaacaaat catggtacgt ttgagcgatg
     2581 gacaatttga ctataagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag
     2641 gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac
     2701 ttcttgctca aggtcaagat gagttgaaat catttgtaga caaacgcatc aaagaacttt
     2761 ataaagatgg aactcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg
     2821 cagaagctga tattaaataa tttcttgaaa tcatccattc tgagtaaggt gggtggtttc
     2881 tcagttttta gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa
     2941 atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa
     3001 tcaaaaaatg gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt
     3061 gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca actgttaacc
     3121 gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggga
     3181 ttaccttgga atttacagag ttcacagact attcacaacc aaacaaagca actgctgatg
     3241 gggaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa
     3301 acggaaaaga ccttgtagcg attggagata cttacatctc tccaatccgc ctttactcag
     3361 gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa
     3421 tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg
     3481 gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa
     3541 atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat
     3601 cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga
     3661 aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg
     3721 cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt
     3781 accacacaga tgacgtgaaa aaagttatcg aagaaacatc agacggtttg gatcaaccag
     3841 tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt ttgtatagag
     3901 cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta
     3961 gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat tattttgagg
     4021 ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag
     4081 tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga
     4141 gctatacagc gccctttgtc atggcatatt tcaagagttc gcgtccagat gccaagacct
     4201 tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg
     4261 atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca
     4321 agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcgc catgatgatt
     4381 tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag
     4441 ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac
     4501 aagggaccaa aaatgccttg gaacaactgg aaatttctgg tggcaataag gggattgtga
     4561 cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggcgttg
     4621 tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc
     4681 gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct
     4741 tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt
     4801 tgcctctctt acaggaggat cggatggcct ttctaaaacg tttctttttc gagccagcgc
     4861 ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg
     4921 cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc
     4981 tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa ttatactata
     5041 ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg
     5101 agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag
     5161 gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc ggtctaggaa
     5221 atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc
     5281 atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat caagttagat
     5341 cagatcgatg tgacttttca tcaaaagaag agaaccatta cagcggttaa ggatgtgacc
     5401 attcacatcc aagaagggga tatctacgga atcgttggat attctggagc agggaaatca
     5461 acccttgtac gggtgattaa cctcttgcaa aaaccatctg cagggaaaat taccattgac
     5521 gacgatgtga tttttgatgg taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt
     5581 caagatatcg ggatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag
     5641 aatgtagcct ttgcccttaa acactctgga ctcagcaagg aagaaaagaa ggctaaagta
     5701 gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta
     5761 tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc
     5821 ttgatttcag acgagtcaac ttctgccctt gaccctaaga caaccaagca gattttggcc
     5881 ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcctgattac gcatgaaatg
     5941 cagattgtca aagacattgc caaccgtgtt gcagttatgc aggatgggca tttgattgaa
     6001 gagagtagtg tgcttgaaat cttctcagac cctaaacaac ctttgactca agactttatc
     6061 tcaacagcta caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa
     6121 cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggatcttc aacagacgag
     6181 ccacttttga atgaattgta caagcattat caagtaatgg ctaatattct ctatgggaat
     6241 atcgaaatcc tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa
     6301 gcagcgctgg caggtgctca agaagccatt cgtcaagcag gcgtacagtt aaaagtattg
     6361 aagggaggac agtaagatgg aatcattgat tcaaacctat ttaccaaatg tctataagat
     6421 gggttggtct ggtcaggcag gctggggaac agctatctac ctaaccctct atatgacagt
     6481 tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac
     6541 agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc
     6601 aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt
     6661 gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt
     6721 tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga
     6781 ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg
     6841 tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc
     6901 tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa
     6961 ccgctacaat cacgatgtga ccatcttggc aaccatcgtt atcattttga ttatctttgc
     7021 aatccaattc ttaggagatt tcttgactaa gaaattgagc cataaataaa aaagagccgt
     7081 gtggctcttt ttaactgatc agattttctg ggcaaatttt ttactcaagg cttgtccaat
     7141 caaggcaccc actagggctc cgatgacaat acttgcgata aatagaagga cagttccagg
     7201 gtttggagcg accatgatgc ggtcgatata ttcttgggat tttcctcttg ccagaagagt
     7261 agccatatag gctttgggcg caatccacat aagcaagatt ggtcctgttg tactaaaggc
     7321 gaaaataatg aaagaaagga agttctttgt tttgtccttg tattttccta aatgagctac
     7381 tccatctgct aggaggccac agataattcc aggaaggaag gaaccagcac cgtgtttagt
     7441 tcccaagaaa aagagggcaa tgacaaggcc gatagtggta atggctccaa agcgcggaac
     7501 ttttgcgact aggatcatat agacgctacc gccgacaagg gcagtaaagg caggcgcata
     7561 aaacatgttt ccagtttggt caaagagatt gcccaaaagg acaccaatcc ccatgcagag
     7621 gaagtaaaga actgcaaaaa gcagtgtagt taagatagat ttcttcatga attgtctcct
     7681 gataattttt tcacaattct cattttacca tggtttggtg ggattgtaaa tggatactag
     7741 aagtttttga aaacgcttga aatatgatat aatggtttca tagttatttt taggggaata
     7801 tcatgggtag atttttagac tttgtcttta atcgtttctt tttagggatg attgcgacag
     7861 ccttcttttg gctattaact ttagcaggag ggattatcct tggtctagcg ccggctagtg
     7921 ccaccttgat gagcttatat gcagaacatg gttatagctt tcgggaatac agtttgaagg
     7981 aggcttggtc tctttacaag caaaatttta tctcaagcaa cctgattttc tatagctttt
     8041 taggtgtggg tctagttttg acctatggtt tgtatctctt ggtgcaattg cctcatcaga
     8101 ccattgttca tttgattgcg acccttttga atgtcctagt agttgccctg atctttttgg
     8161 cttatacagt atctttaaaa ttacaagttt attttgcctt gtcctatcga aatagtctca
     8221 aattatcctt gattggcatc tttatgagtc tagcagctgt ggctaaggtt ctccttggga
     8281 ctgtgctact tgtagcaatt ggttactata tgcctgccct gctatttttt gtaggaattg
     8341 ggatgtggca tttctttatc agtgatatgt tggaacctgt ctatgaaatc atccatgaaa
     8401 aattggcgac aaaatagaat gaagcacttt tggctacata cgcttctaag aacctatagt
     8461 tcagtgatga tcattatcat tgcgagtttt gcaatcttac tctcttacgc tgactgggat
     8521 tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa ctgctagaac agtgagtgaa
     8581 attgaatatt accatagaga gtcaacccag atagctcagg ctttagttga aaaccaagct
     8641 cgtattgagg gaatctataa atactttagc cttagcatgc cagactattt ttactggcaa
     8701 ttagagcgga aagtttcgcc ttatatatca gtctctctgt atgaaaatgt tgatgacctc
     8761 tatgttcgaa atgattttgt aactggggtg gccattgctt ttcaagatta caaggaagtc
     8821 tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca gggctgagga tttcaaacca
     8881 gcaggaaata gttttgccat tccagtgtca gatccagtgt cagatcaaga cttaggagtg
     8941 atttacatct ccttggatcc tgctgtttta taccatgcca ttgataatac tagaggtcat
     9001 actccgatgg cagtaacagt gacctcacct tttgatacgg agatttttca tattggtgag
     9061 acagttgata aggagagtga aaattggcta gttggcttaa cttctcatgg ttatcaggtt
     9121 caggtggcag ttcccaaaaa ctttgtttta caaggaacgg tgaccagctc tgctttgatt
     9181 gtgggcttga gccttctctt tattgtcatt ctttatctga ctttgaggca gacctttgct
     9241 aattatcaaa agcaggtagt ggatttggtg gattccatcc aagctattgc ccaaggacaa
     9301 gaaggtcttc gcattgatac gcttgaaaag gatcaggaat tgctcctaat cgcggagacg
     9361 accaatgata tgttggatcg attggaaaag aatatccatg atatttacca gttagagctt
     9421 agtcaaaaag atgccaatat gcgagccttg caggcgcaaa tcaatcctca ttttatgtat
     9481 aatacgctgg agttcttgcg catgtatgca gttatgcaga gtcaagatga gttggcagat
     9541 atcatttatg aattcagtag tctcttgcgt aacaatattt ccgacgaaag agagaccctc
     9601 ctcaaacagg aattagaatt ttgccgtaaa tacagctatc tctgcatggt tcgctatccc
     9661 aagtccattg cctatggttt caagatagat ccagagttag agaatatgaa gattcccaag
     9721 tttaccttgc aaccgctggt agaaaactat ttcgcgcatg gtgttgacca caggcggaca
     9781 gataatgtga ttagcatcaa ggctcttaaa caggatggtt ttgtggaaat tttggtggtc
     9841 gataatggta gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa attaagtcag
     9901 aaatattttg aacaccaagc cagctacagt gatcaaaggc agtctatcgg aattatcaat
     9961 gtacacgagc gttttgtgct ctattttgga gaccgctatg ccattacgat agagtctgca
    10021 gagcaagccg gtgttcagta tcgtattaca attcaagatg agtagaaagg gagaaaatgt
    10081 ataaagtatt attagtagat gatgagtaca tggtgacaga aggtctgaag cgtttgattc
    10141 cctttgataa gtgggatatg gaggtcgtcg caacagccag tcatgccgat gaagctctag
    10201 aatatgttca ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg ccagacaaaa
    10261 cagggcttga tatgattcgg gagatgaaag agatcttacc agatgctgcc tatatcctgc
    10321 tctcaggtta tcaggagttt gattatgtaa aaagagcaat gaaccttagt gtggtggact
    10381 atttggtcaa gcctgttgat aaggtagagc tgggaaatct gctggagaag attgcaggtc
    10441 agctcggcga gagagggaag aaaagtcaga ctcttagtca agaattagac gaggctggat
    10501 ttgttagtta tttaggggat aaggagaatt ggtggatagg tctatccaag gaaaaacaag
    10561 gttccttcac cattccctac tatgtcttgg gccaagactg gcagattttc atttctgacc
    10621 aacccctaga tggtttagtc gttacacctt ttgaagctcc ttatcaagaa cactttgaac
    10681 gctggaagct gaatgctgag aaaaccctct tttacggttc tgtaaatttg cagcagtctg
    10741 agagtctctt tgcctattac gaaccgattt atagggttat cattcaggga aatctcaatc
    10801 aaatcgtaga agagttaaat ctcttggaga aggtagttct tgaaaatacg ccgcgtgttc
    10861 cgattactaa acagcttttt attcagtttg tcatggatgt tttccattta tttgaacatc
    10921 tcaaagctga tgacctgaca gacatcgtca aaaccattca tgctattcaa tccttcgatg
    10981 aattggttcc ttatatcaag gaaactctga gcagcttttt cggtcaatac cgtatgaatg
    11041 aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta ccaaaaagag ctttccctca
    11101 aggatatcag taaggctctc tttatcaatc ctgtctatct agggcagttg attaagcgtg
    11161 aaaccgattc gacttttgca gagttactaa acaaacaacg tattaaggct gcccaacaac
    11221 ttttgctttc aactagtgac agcatcgaag atatttgtta tgctgttggt tacagtaacc
    11281 ttggatattt ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa gcctaccgaa
    11341 aacaggtaga aactatacta taagatttgt attcctttac aaaatgtgct ataatataaa
    11401 tattattatt aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa
    11461 tcttgtctgc ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta
    11521 aagaagccct tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag
    11581 accagcttaa ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt
    11641 tgattgtgct atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt
    11701 tgcaatatgc aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt
    11761 atggctatgt tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga
    11821 cagtgagtat tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc
    11881 tagcccttgt cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa
    11941 cagaagagct tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg
    12001 ttttttgatt atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat
    12061 tagtttgagt ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca
    12121 gtacaaaggg attgaggttc aaaagattca tatcaaggat ttggtcaagg aaggcaaaaa
    12181 tttctacgaa atggaccatc cctatgttgc ttttttgccg acctatctcg aaggtgggaa
    12241 tggcgtggat aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta
    12301 tggtaacaat gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa
    12361 ccaatactgc ctaacagcca agcaatacag tcaacgcttt ggctttcctg tattggctga
    12421 ctttgaaatg cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt
    12481 gtatgagttg gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct
    12541 agtcgcaggt tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag
    12601 agattctcga atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt
    12661 gagtataaac agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt
    12721 cttatgcttt ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt
    12781 catctcgcgc ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg
    12841 gcgaagccaa agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga
    12901 tttttgtttt cacgtgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg
    12961 aaagagccaa tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata
    13021 atgatgatac cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattatcc
    13081 tctttttgac tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata
    13141 acagttataa ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac
    13201 cattcgccaa gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca
    13261 gcttcaaccg cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg
    13321 gctaggatag ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta
    13381 aagttgacgg tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata
    13441 ggagccggca tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt
    13501 gtcttctcga caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgca
    13561 agaacagtcg caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg
    13621 tagcctccaa agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta
    13681 atgctaagtc caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca
    13741 ccagccgtgt tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt
    13801 tttccttttt cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca
    13861 ccaaaacgga aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac
    13921 caaccgtaag aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca
    13981 gttgccatta ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt
    14041 aaggaaatag cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata
    14101 tgtaatctat attctacaaa aaattttgga aaaatgcaag agtattttga aaaaagatag
    14161 aaaatttaca aagaaaatct gaaataactg ttatgatata gaggattgaa actagaatag
    14221 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttatcc
    14281 tgttcttatt tcatttcact atagtaaggt gcagcaggat aaagcaaatc cgagaagttt
    14341 ctttctcgga tttgcttatt atgaggttcc tattttctat gctccaagag ttgattgatg
    14401 tgatctactt ttttagcctc tcttttatag agaatagccc agatgatgag atagacaatc
    14461 gcaaactcga taatgagctg gaggtagaaa atccagtgga aagggaacca accagcaaga
    14521 gttgctagtg ggacaaagcc agccagcata aggaagaaat gagtcagagt ggcacgaagc
    14581 atgctccagt cacggctaaa taagcggttg ccaaagttga agagcatacc gatggttgcc
    14641 catataagtg tgcagtagag caagaccagg gcaccgtgaa cctgatgctg atccatcact
    14701 tggccgatga gagagtaggg atttagtggt gcgtaggtat ttggtgcata aatgagtgaa
    14761 aagaggatag agaggatgag gccgataaga acaccggtag ctgcatcgtg aaatacttgt
    14821 tttttcatag ttctaatttc tccttgatgg tttttagata acggcgtgaa gagtaggtga
    14881 agctttcgtt tttcaagaaa atttctacca gaccgtttgg cgtgagcttg aggtgagaga
    14941 tggaatcgat attgatgatt tctgattggg aaatttggat aaaattggtt ggcaagagtt
    15001 taagaacctg atagagtcgc aaatcaatgc tgtaggtctg actcgcggtt tctgctagaa
    15061 ccttccgatt ctcgatatag aagcgctgaa tcttgccaat ctcaactaga tagacctgat
    15121 catcgatttt tcctttgatt ttttctcttt ggtccagatt ttctgcgaac tcgatgactt
    15181 tctggacttt ttcggtttct tgaggtgctt ggacaatcag cttttcctcc tcgtaagtct
    15241 cactaatctg tagttctact ttcatagttt tctctccttt tcagttatac aaggttgtga
    15301 tcacttcctg tatatcctta ttaaacacta ttttatagcc catggcaagg aaccttgtct
    15361 atgtggaggg attgggctcc tatgtggtgg agcttttctg ttctttctga aatatggtat
    15421 aatagcacta atcaatttct aggaaaatag atacggaaag gggctgaaag aactagggga
    15481 acagttggaa ttagaaagtg ataggtatga aaagtggcgt tgaagctgaa taagtttata
    15541 aagcgtttga atgaagaaat ggaaagtaaa taagttgacg atgaattaca aaatagattt
    15601 tatctacaat ttgtatcttt caaatcattg atttgaattt tagatttaat catgttacaa
    15661 ttaaaactga aatcaaatag aagaggaaaa tgcaaacgtg ggcacactat tagcaacaag
    15721 attaaaaaat agacggaaag aattaaaaat gtctcagcga gaactagctg aaggtatctg
    15781 taaacagggg caaatcagtc gattagagag cggagagttt acccctggag cggatttcct
    15841 gaatgccctt gctaagaagt taaaagtcag tatggattat ttttttgatg agcaggttgt
    15901 agagaaagtt gaggagttat cagaatttaa gaaattagca cagacattta ttacaaatcg
    15961 caattatgag tctttgaaat atatatatga attggagaat gtaaaagctc accgcctatc
    16021 tttagcagat aaaatctaca tggaatggat aaaatctctg atagattttt atttttacgg
    16081 acagaaagaa gatgcgattg tacgattaga gggggtatta tcacagttaa gtgtatctga
    16141 tttgaactat ctccaagttt caaacaccct attcaatttt tattatgata ttggagattt
    16201 aggtcgtttc aataaaattc gtgaaaaact agagtatcaa gtaaatcacc tcaatttgag
    16261 tacaatcgaa gagttagaac tatctattaa gtttaactac aacgtttgtc gttatctatg
    16321 gttacagaaa aatattgaag aagctattac taaaattaca gctactataa aacaatgtaa
    16381 ggcttacaga acgaattatc ttttggctga tttgtactta ttgatgggaa atgtaagtga
    16441 aaatttttct tctaaaagtt cggtgaaaga atattttgag acggcatatt ttctatacaa
    16501 acttgaggag aacatgtcaa tgactctgaa agttgagcat tacattgcag atataacaga
    16561 ataatgaata cggtgttcaa gtgagcatcg tttttcaaac ctagttcaga tacaaaaaag
    16621 tatcaaacaa aaaaaaataa aaaaacatta taaaaacaat tgacaagcta attttgaagt
    16681 gataaattaa atgcaagaaa acaaaaggag aggtatatga gaagtttgtt taagaaaata
    16741 gttgctgtat tagttattgg cttaattctg ttaggaattg cgagaacacc tcaagttcat
    16801 aagatggcta gagggattga tcctggtcct gcgaatttta tttagaaatc aatttctact
    16861 aattgagtac taattgagta ttaatgggta aaaagattgt atggataaga aaaatttact
    16921 tgtattggtt actggttcgg taggtgccag taatgtagat acatacttat attatataaa
    16981 aaaattctat aatgttaaag tgatactttc tgaaaattct aaaaaattta taagtaagga
    17041 attaattagt tatttttgtg ataaagttta tgatgaaata tttgttgaag aggtagttcc
    17101 gcacgttttt ctgccatatg aatctgactt acttcttatt ttaccagcta cggcaaatgt
    17161 gattggcaaa attgctaatg gtattgctga tgatttagtt acagcaactg ttttaaactt
    17221 taataaaaaa ataatttttt gtcccaatat gaactctact atgtgggaca atcacatagt
    17281 tcaaagaaat gtatcaattc taaaggagtt gggacatata tttttatttg agtctaaaaa
    17341 aacatatgag gtaggattgc gtaaagcaat agattcaaca tgttcaatgt tacaaccaca
    17401 gtcgttagta aaagaactta tcaaattaga aaatattgtc cttgaagagg gacattaaaa
    17461 actactgaga atattaagga ggggaaaaaa tggaaaattc atcaatcgat gtagatatgc
    17521 tgttggaaga attgacacaa gaagcaatgg tcgttgttgc tgttgataag gactgttaat
    17581 ttaaacttat ggcaatatat gaaaggttac tggatgtttt aaattatgca ggcagtagcc
    17641 ttttattata tacaaatgga taaagtaagg ataatacaat gattaataaa aaaatacaac
    17701 aagttgtttt ggaatcatta cagaattttt tgaatgggaa cttcatttcg ccttgtgtag
    17761 tctatgattt tggcttgctg gaaactgtac ttgatgaatt taaaaatcaa attcctgtaa
    17821 cattcaatta ccaacttttt tatgccgtta aagcaaattc aaatgagaag atacttgaat
    17881 tcttagtaga taaaattgat ggagttgatg tggcgtcatt atctgaatta gatgtggcta
    17941 aaaaattttt cccaccaact caaatttctg ttaatggttc cgcattttct tatgaaactt
    18001 tatataatct gattaaaaaa caatataaag ttgatattaa ctttttggaa catcttcaac
    18061 aattttcccc aaaagaatct gttggaataa gagtaacgga gccagatgaa cttaataatc
    18121 gtatgagtcg atttggaata aatatttgca gtgataattg gactagtaat ttacaaaatc
    18181 cttta
//
LOCUS       DAVLZG010000043        18162 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLZG010000043 DAVLZG010000000
VERSION     DAVLZG010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.043"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            72..359
                     /locus_tag="VYO72_001441"
     CDS             72..359
                     /locus_tag="VYO72_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707793.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLG"
     gene            969..1661
                     /locus_tag="VYO72_001442"
     CDS             969..1661
                     /locus_tag="VYO72_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1707794.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1714..4125
                     /locus_tag="VYO72_001443"
     CDS             1714..4125
                     /locus_tag="VYO72_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1707795.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4375..5076
                     /locus_tag="VYO72_001444"
     CDS             4375..5076
                     /locus_tag="VYO72_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707796.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5078..7786
                     /locus_tag="VYO72_001445"
     CDS             5078..7786
                     /locus_tag="VYO72_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1707797.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGCFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NVFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7882..8373)
                     /gene="tpx"
                     /locus_tag="VYO72_001446"
     CDS             complement(7882..8373)
                     /gene="tpx"
                     /locus_tag="VYO72_001446"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1707798.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8496..9425)
                     /gene="psaA"
                     /locus_tag="VYO72_001447"
     CDS             complement(8496..9425)
                     /gene="psaA"
                     /locus_tag="VYO72_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1707799.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKATTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9457..10305)
                     /locus_tag="VYO72_001448"
     CDS             complement(9457..10305)
                     /locus_tag="VYO72_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1707800.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10302..11024)
                     /locus_tag="VYO72_001449"
     CDS             complement(10302..11024)
                     /locus_tag="VYO72_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1707801.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11315..13207
                     /gene="pepO"
                     /locus_tag="VYO72_001450"
     CDS             11315..13207
                     /gene="pepO"
                     /locus_tag="VYO72_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1707802.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13330..13959)
                     /locus_tag="VYO72_001451"
     CDS             complement(13330..13959)
                     /locus_tag="VYO72_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1707803.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14955..17177
                     /locus_tag="VYO72_001452"
     CDS             14955..17177
                     /locus_tag="VYO72_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1707804.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17207..17650
                     /locus_tag="VYO72_001453"
     CDS             17207..17650
                     /locus_tag="VYO72_001453"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1707805.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGANMQVELVNNGPVTIILDTKKR"
     gene            complement(17689..18104)
                     /locus_tag="VYO72_001454"
                     /pseudo
     CDS             complement(17689..18104)
                     /locus_tag="VYO72_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5380 a         3421 c         4189 g         5172 t
ORIGIN      
        1 gaaaatactt tttttaaaaa gcaaatatga tacaatttta tttgaaaaaa aataaaaaag
       61 gagattttat tatgaaatca agtggtatcg tcggtcttgt gggaggaatt ttacttctta
      121 tttgtccttt tgtcttgttg ggaacagcgg taaatacagc tgctacaact cttaatggag
      181 gagctactgc aggggctttt tcaggtgttg ccttactctt gaataccttg aagattgcaa
      241 atcttgttct tggtatcatt gctattgttt actataaagg agataagcat gtaggtgcag
      301 ctccgtctgt actaatgatt gtttctggtg aagttagtct cattccattc ttaggatgag
      361 ttggggggat tcttgctatt atcggaggat ctctattcct tgcaacattg aagaaattca
      421 aatcagaaga ataaaaggta ttttagcatg aaaagaacaa aaaagtttat cggtatagga
      481 gtagctctat tatctctttc tcttctagtt gcatgtggaa cataaagttc aaagaatact
      541 tcaacaagta atgatgagaa gacagtagca acatccaata gttcaaaaga aacaatcact
      601 ttcgatacac cggttgtaac agacgatgcg attgaatcaa tacgcactta tgcagattat
      661 atagatcttt ataaaaatat ttttgatgat tattttacta aagctgagga aggtttcaaa
      721 ggcacagtta tggaaaataa tgactcgttt actaaactaa aagagtcaac tcaaaaatta
      781 ttcgatgcgc agaaaaaaag gttaaataat gaagatagaa tagaaacagc caaaaacaat
      841 gtgattgcca aacattgtca aacagtcctt tcctttttgg ttttgactag cttttttgtg
      901 aaaaattgtg taaaatagaa tagataaacg aggggaaacc tcggaaaatt taaaggagaa
      961 tccatctaat ggtaaaattg gtttttgctc gccacggtga gtctgaatgg aacaaagcta
     1021 accttttcac tggttgggct gatgttgatt tgtctgaaaa aggtacacaa caagcgattg
     1081 acgctggtaa attgatcaaa gaagctggta tcgaatttga ccaagcttac acttcagtat
     1141 tgaaacgtgc tatcaaaaca actaacttgg ctcttgaagc ttctgaccaa ttgtgggttc
     1201 cagttgaaaa atcatggcgc ttgaacgaac gtcactacgg tggtttgact ggtaaaaaca
     1261 aagctgaagc tgctgaacaa tttggtgatg agcaagttca catctggcgt cgttcatacg
     1321 atgtattgcc tccaaatatg gaccgtgatg atgagcactc agctcacaca gaccgtcgtt
     1381 atgcttcact tgacgactca gtaatcccag atgctgaaaa cttgaaagtg actttggaac
     1441 gtgctcttcc attctgggaa gataaaatcg ctccagctct taaagatggt aaaaacgtat
     1501 tcgtaggagc tcacggtaac tcaatccgtg cccttgtaaa acacatcaaa ggtttgtcag
     1561 atgatgagat catggacgtg gaaatcccta acttcccacc attggtattc gaattcgacg
     1621 aaaaattgaa cgttgtttct gaatactacc ttggaaaata aaaaattgta agcctaggat
     1681 tgatttctag gctttttatg ttagtatgga agtatgataa ggaataaaaa acaagattat
     1741 gtactggcct acaaacaacc agcttcaacc acttacatgg gttgggaaga agaagcttta
     1801 ccgataggta atggttcttt aggagcaaaa gtatttggcc gtataggggc tgaacggatt
     1861 caatttaatg aaaaaagtct ctggtctgga ggtccacttc ctgatagttc agattatcag
     1921 ggtggaaatc ttcaggatca gtatgttttt ttagctgaga ttcggcaggc tttggagaag
     1981 agagattaca atctggctaa ggaactggct gagcagcacc taattgggcc aaaaacgagt
     2041 caatatggga cctatctgtc ttttggggat attcacattg agttcagcca gcaaggtacg
     2101 actttgtctc aggtgacgga ctatcagaga cagctgaata ttagtaaggc acttgtgacg
     2161 acttcttatg tctataaggg aacgcgattt gaacgtgaag cttttgcgag ttttccagat
     2221 gatctcttgg ttcagcgttt tactaaggaa ggggcggaaa ctctagattt tactatagaa
     2281 ctatccttga cctgtgattt ggcttctgat gaaaagtatg agcaggaaaa atctgattac
     2341 aaggagtgta agttggatat tactgattct catatcttga tgaagggaag agttaaggat
     2401 aatgatctgc ggtttgctag ttatctagct tgggaaacgg atggagatat tagagtttgg
     2461 tcagataggg ttcagatatc aggagccagt tatgccaatc tcttcttggc cgctaagacg
     2521 gattttgccc aaaatcctgc tagcaattat cgcaagaaac tagatttaga gcaacaggtg
     2581 atagacttgg tggacacagc taaagaaaag ggctataccc aattgaaatc aaggcatatc
     2641 gaggactacc aagccttatt ccagcgtgtt caattggatt tggaagctga tgttgacgca
     2701 tccactacag atgatttgtt aaaaaattat aagccacaag aagggcaggc tttggaggag
     2761 ctgttcttcc agtatggacg gtatttattg attagttcgt ccagagactg cccagatgct
     2821 ctaccagcta acctacaggg agtctggaat gcggtcgaca atcctccttg gaattcggac
     2881 tatcacttaa atgtcaatct gcagatgaat tattggccag cctatgttac caatctccta
     2941 gaggcggtct ttccggtcat caactatgta gatgatttgc gtgtctatgg tcgtctagcg
     3001 gctgtaaagt atgcaggaat cgtctctcag aaaggtgagg aaaatggttg gttggttcat
     3061 actcaagcga ctccctttgg ttggacggca cctggttggg attactattg gggttggtca
     3121 ccagctgcca atgcgtggat gatgcaaacc gtttatgaag cctattcatt ttatagggac
     3181 caagactatc tcagggagaa aatttatccc atgttgaggg aaacggttcg tttttggaat
     3241 gcctttttac ataaggatca gcaggcgcag cgttgggtgt cttctccgtc ttattctcca
     3301 gaacatgggc cgatttcgat tggcaatacc tatgaccaat ctctgatttg gcagttattt
     3361 catgatttta ttcaggctgc tcaggaattg ggactggatg aggacttgtt gactgaggtt
     3421 aaggagaagt ctgatttact aaatcctttg caaatcactc aatctggtcg aatcagggag
     3481 tggtatgagg aggaagagca gtattttcaa aatgagaaag tggaggccca gcaccggcac
     3541 gcttcccatc tagtgggact ctatcctggc aatctcttta gctacaaggg acaagagtat
     3601 attgaagcgg cgcgtgctag cctcaatgat cgtggagatg gcggcacagg ctggtccaag
     3661 gctaataaga tcaatctctg ggcgcgtttg ggagatggca atcgagccca taaattattg
     3721 gcagagcagt taaagacatc caccttgcca aatctttggt gtagccatcc tccttttcag
     3781 atagatggta attttggtgc tactagtggc atggcagaaa tgttactcca gtctcatgca
     3841 gcttatctgg tacctctagc tgccctacct gatgcttggt caacaggttc tgtttcaggc
     3901 ttaatggcac gtggacattt tgaagtgagc atgagctggg aagataaaaa actcttacag
     3961 ttgaccattt tatcaaggag tggaggagat ttgcgagttt cttatccaga tattgagaag
     4021 agtgtgatta aaatgaatca agaaaaaata aaagcgaaat gcatggggaa agattgtatt
     4081 tcggtggcaa cagcagaagg tgatcttgtt caattttatt tttaagaaga tgttataagg
     4141 cagtaatttg aaactgcctt ttaataagga tttaagaata taagcagttt tcaactagtt
     4201 gaaaaagcgt tataatgata ataggaagta atactcaatg aaaatcaaag agcacaaaca
     4261 aggaagctag ccgcaggttg ctcaaaacag tgttttgagg ttgcagatgg aagctgacgt
     4321 ggtttgaaga gagattttcg aggagtataa tttgtttgat agagggtggg tctgatggct
     4381 tatattgaga tgaaacactg ttacaagcgt tatcaggttg gggacacgga gattgtggcc
     4441 aatcgtgatg tgaattttga gattgaaaag ggggagctgg ttattatcct tggtgcttca
     4501 ggtgcaggca agtcaacagt gcttaacctt cttgggggaa tggataccaa tgatgaaggg
     4561 gaaatctgga ttgatggtgt taatattgcg gattatagtt cccaccagcg caccaattac
     4621 cgtagaaatg atgtggggtt tgtttttcag ttttataatc tagtttctaa tctgacagct
     4681 aaggaaaatg tggaactggc ttctgaaatt gtgacagatg ccttgaatcc tgatcaggtc
     4741 ttgacagatg taggtctggc tcatcgtcta aataactttc cagcccagct ttctggaggg
     4801 gagcaacagc gagtctccat tgcacgcgcg gtagccaaaa atcctaaaat tcttctttgt
     4861 gatgaaccta ctggagcctt ggattatcag acgggcaagc aggttttgaa aattctccaa
     4921 gatatgtctc gtcaaaaggg agcgacggtg atcatcgtga ctcataatgg agctttggcg
     4981 cccattgctg atcgcgtgat tcatatgcac gatgccagtg tcaaggatgt ggtgctcaac
     5041 cagcatcctc aggatattga cagtttggag tactagtatg atcaagcgaa aaacttattg
     5101 gaaggactta attcagtcct tcacaggctc caaggggtgt tttttatcca tcttgatcct
     5161 gatgatgttg ggatctctag ccttagtagg cctcaaagta accagtccca acatggaggc
     5221 gacagctaat gcttatttaa caactgctca aaccttggat ttggcagtca tgtctaacta
     5281 tggcttggat caagcagacc aagaagaact aaaacagacg gagggcgcag aggtcgagtt
     5341 tggctatttg acagatgtga ctatggataa tgggcaggat gccattcggc tgtactccaa
     5401 accagagcga atttcaacct ttcagctaag aaagggacga cttcctcagt cagacaagga
     5461 aatcgctttg gccactcatt tgcaaggcca atacagcgtg ggacaggaga ttagttttaa
     5521 agaaaaagaa gagggtcatt cctctttaaa agaccatact tataccatta ctggttttgt
     5581 ggattcggct gaaatcctct cccagcgaga tatgggctac gcaggaagtg gaagtgggac
     5641 tctgacagcc tatggggtga ttttacctag tcagtttgat cagaaagtct acaatatagc
     5701 tcgtttgaaa tatcaagatt tagcaggttt aaatgtcttt tcatcagctt atgaagaaaa
     5761 atccaagcaa catcaggaag agcttgaaca aattttatca gataatggca aggtacgtct
     5821 gcaacttttg aaaaaagaag gacaagagtc tctagacaag gggcaagaga cccttgacaa
     5881 ggctcagact aatttgcagg aaggcaagcg tcgtttagca gctgctcaag ctcgtataca
     5941 ggctcaagaa agtcaactag ccttgtttcc tcaagttcag agagagcagg ctagtgctca
     6001 acttacccaa gccaagcagg aattgggcaa ggaagaggac aaactaaagc aagctgaaca
     6061 aaatctagcc caagaaaagg aaaaattaga aaaacatcag caagtcttgg acgatttggc
     6121 ggagccaagg tatcaggtct ataatcgtca gaccatgcca ggtggtcagg gctatcttat
     6181 gtatagcaat gcttcatcca gtattcgagc agtgggcaat atctttcctg tggtacttta
     6241 tgccgtagca gccatggtga cctttacgac catgactcgc tttgtagacg aagagcgaac
     6301 tcatgcaggg atttttaagg ccttgggtta tcgtagtaag gatattatcg ccaagtttct
     6361 cctttatgga ctagtagctg ggactgtcgg aacggctcta ggtagtatac ttggtcatta
     6421 tttgctagcc agtgtaattt caagtgtcat tacaaaaggc atggtggtgg gagaaaccca
     6481 gattcagttc tattggacct atagcttact agcttttgtc ttgagcttgt tggcgagtgt
     6541 gttaccagcc tatctggtgg cttggaggga acttcatgac gaagcagccc agcttctact
     6601 tcctaaacct cctgtcaaag gagctaaaat cttattggag cgtatcggtt ttatctggcg
     6661 tcgtctcagt tttactcata aggtaacagc ccgcaacatc tttcgttata agcagagaat
     6721 gttgatgaca atctttggtg tggcaggttc tgtagctctg ctctttgcag gtttgggaat
     6781 ccaatcttct gtagcaggag ttccgtctaa acagtttcaa caaatccaac agtatcagat
     6841 gcttgtctct gaaaatccta gtgcgaccaa tcaggacaag gtagagctag cagaagtgtt
     6901 gaaagggcag gagatactag cctaccagaa aatctattct aaagcgctat acaaggattt
     6961 caaaggcaaa gctggtcttc aaaacattac tcttatgatg atagagaagg aagatttgac
     7021 tccctttatc catcttcaac atcatcagca ggagctgaca ttaaaagatg gcatcgttat
     7081 tacagctaaa ctcgcccagc tggcaggtgt caaggttggg cagactttag aaattgaagg
     7141 taaggaacta aaggtcgctg ctattactga gaactacgtt ggtcacttta tttatatgag
     7201 tcaggctagc tatgagcaac tttacggaca gctaccccaa gccaacactt atctggtctc
     7261 attaagggat accagtgcaa ctagtatcga aagtcaggcg ggcttgctta tgaatcaatc
     7321 tgcggtgtcc agcgttgtcc aaaatgcttc agccattcga ctcttcgact ctatcgctag
     7381 ctcactcaat cagaccatga ccatcttggt catcgtatcg gttctattag ctattgtcat
     7441 cctttacaat ctgaccaata tcaacgtagc tgagagaatc cgtgaactct ccactatcaa
     7501 ggttcttggt tttcataata atgaagtcac cctctacatt taccgtgaga cgattgtgct
     7561 gtcccttgtg ggaatcgtac ttggtctgat agctggtttc tatttacacc aatttttgat
     7621 tcaaatgatt tcgcctgcga ctattctctt ttatccgcag gtaggctggg aagtctatgt
     7681 aatcccagtg gcagcagtaa gcatcatttt gaccttgctt ggtttcttcg tcaattatta
     7741 tctgagaaag gttgatatgt tagaagccct gaaatctgta gagtaaggta gttattttta
     7801 gctgattgaa cttctattta ctaatattca aaaatcctcc gtttcaaaga gcagggaact
     7861 ctttgtgaca gaggattttt tctatagggc tttagcagct gcaattgcgg cttcgaagtt
     7921 tggctcagaa ttgatattat ccacgtattc aacgtagcga atcgtattgt cagtatcgag
     7981 gacaaagact gcgcgtgcta ataggtgcca ttcgttgatc aagagggcat aatcgtgccc
     8041 gaaagaatgg tcaaagtagt ctgaaagcat aatggcattg tcaaggcctt cagcaccgca
     8101 ccaacgtttt tgagcaaaag gtaggtccat tgaaacagtc aatacgaccg tgttgtccag
     8161 tccagccaat tcttcattaa aacgacgtgt ttgagttgag cagatgcctg tatcgataga
     8221 aggaacgaca ctcaagactt ttttcttgcc atcaaaatca gccagagatt ttttagaaag
     8281 atctgttgta gtaagagaaa aatcaagcgc cttgtcgccg acttgtagtt gtttacctgt
     8341 aaagctcaca ggatttccga gaaaagttac cataggatac tccaatcttt tttcttccat
     8401 tgtatctgaa acagtcagaa ttttccaatg atttgaccgg aaatgtgggc atagaaaaaa
     8461 cgccagctca tatgagaatg acgtttttca gaggcttatt ttgccaatcc ttcagcaatc
     8521 ttgtcaaggt tgtatttcat catgctgtag tagctgtcgc cttctttacc ttgttctgcg
     8581 atagagtcag taaagatttg tgcgtagatt gggatgtttg tgtcttgaga aacggttttc
     8641 attggacggt catccacact tgattctaca aagagtgatg gaacttttgt ttggcgaagt
     8701 ttttcaacca aggtcttgat ttgttcagga gttccttctt cttcagtatt gatttcccag
     8761 atgtaggcac ttggaacacc ataggcttta gagaagtatt tgaatgctcc ttcgctggtt
     8821 acaatgagtt tcttttcagc agggatctta ttaaatttat ccttactttc tttatcaagt
     8881 ttgtctaact tatcagtata ttctttgaga tttttttcat agaattcttt attgttaggg
     8941 tctttggcgc tcaattgttt ggcgatattt ttagcaaaaa taataccgtt ttcaaggtta
     9001 agccaagcgt gtgggtcttc ttttcctttt tcattttgac cttcaaggta gataacatca
     9061 acgccgtcgc tgactgcgaa gtagtctttg ttttcagttt tcttggcatt ttctaccaat
     9121 tttgtaaacc aagcattgcc acctgtttca aggttgatac cgttatagaa aatcaaatca
     9181 gcctcagaag ttttcttaac gtcttcagga agtggttcgt attcgtgtgg gtcttgccca
     9241 atcggaacga tactatgaag gtcaattttg tcaccagcaa tatttttagt aatatcagcg
     9301 atgattgagt ttgtagcaac aacttttagt ttttgaccag aagttgttgc tttttttccg
     9361 ctagcacatg ctacaagaat gattgcagaa agaaagagaa cgagtaatgt acctaatttt
     9421 ttcattagat cctccaattt attagggctt tgccccttat tttaacaaat gtttattttt
     9481 cagtttcaaa tatcgttgtt tgggagcgat aaagaagcta atgagaaaga aactagcagc
     9541 tgtaagcacg atactagaac ctgccgcaac attaaaacta tagccaataa agagtcccaa
     9601 aactgaagca gtagctccga aggttgagga aaggaaaatc atgcttttca gactattagc
     9661 atacagataa gcagttgcag ctggggtaat cagcatggct acaatcagga tagttccgac
     9721 actttgcatg gctgtcacag acacgagagt caggagtacc atgagaaggt agtgatagaa
     9781 attgacaggc attcccatgg ctttagccaa gagttcatca aaggaagtta tcaagagttg
     9841 cttgaagaaa atccagatta acaagaggat ggctgccccc acacccatag taataaacat
     9901 atccgtatct tggacggcca ggatattacc aaaaaggata tggaaaaggt cagttgaact
     9961 tttagcgaca ccaatcaaga tgataccgag ggctaagaaa gaagaaaagg taatgccgat
    10021 ggcggtatcg cttttgataa tcgagtttcc tttgatgtag gtaatgatga tggcagctag
    10081 caatccaaag acaatggctc cgataaagaa gtcaaggccc aagatgaagg agagggctac
    10141 acctggtaag acagcatgtg aaatggcatc tcccatgagt gacatcccgc gtagaataat
    10201 gaaacatccc acggctccag ctacaatccc gacgacaata gctgttatca aggcattttg
    10261 taggaaatgg aatttttgca atccatcgat aaattctgca atcataggtc acctccattg
    10321 aaaaagagtt gattaccgta agcttctttt agattggttt cggtaaaagt ttcttttgtt
    10381 ggaccaaagg caatcacttc tcgattgaca agtaagactt gatcgaagta gtggggaatc
    10441 ttgctgaggt cgtggtgaac gatgagaacc gtcttcccag cttttttcaa atctctcagc
    10501 gtattcatga tgatttcctc actgacagag tcaatcccag caaagggttc atccaagagg
    10561 atatagtcgg cttcctgcac caaacatctg gcaatcaaga cccgctggaa ttgacctcca
    10621 gacagttgac taatttgacg ttcagcgtag tcagctaggc cgacgatttc aagggcctct
    10681 tgcactttct tccaatgttt agcctttaaa cttcgaaaga gaggaataga gggaaatagt
    10741 cctaacgaga cgcattcctt gaccttgatg ggaaagttgt agtcgatatt gattttttgt
    10801 tcgacatagg caattcggtg taaggatttt ttaacttcct tgtcatcgag aaatgcctga
    10861 ccttgatgtg ggataattcc cagcatacct tttaatagtg ttgatttccc agcgccgttt
    10921 ggaccaatga tgccggtaat tgttggtcca tggagcacta gtgaaatatc cttaagtgcc
    10981 aacgtttctt tgtaggagac actgaggttt tcgatacgta tcataaactt gtattcctcc
    11041 tgtctcttaa tatacattaa aaaaaaaatt aagtcaagtt aatttttgaa aaaattaaaa
    11101 taataactga aaaatagatt ctaaagataa ctttcaggat aaatttctaa attataaaac
    11161 gcatagtatc aagtgtaaaa aacttggaat tatgcgtttt atcatggaaa gattttttat
    11221 aatagctaaa aaataatagt taaatggtta ttaattgcat tccctagtga tttttgttaa
    11281 gataaatgca aatacaaatg aaagcgagaa caagatgaca cgttatcaag atgattttta
    11341 tgatgctatc aatggagaat ggcaacagac agctgaaatc ccagcagata agtctcaaac
    11401 tggaggtttt gttgatttag accaggaaat tgaagacctg atgctggcga caacagacaa
    11461 gtggttagca ggtgaagaag tgcctgagga tgctatcttg gaaaactttg tcaaatacca
    11521 ccgcctagtt cgtgattttg acaagagaga agctgacggt atcacacctg tcttaccact
    11581 ccttaaagaa ttccaagaat tggaaacttt tgcggatttt acagctaaac tagcagagtt
    11641 tgagcttgca ggaaaaccaa acttccttcc ttttggtgta tcgccagact ttatggatgc
    11701 tagaatcaat gttctatggg ctagcgctcc aagcacaatc ttgccagata cgacctacta
    11761 tgcagaagaa catcctcagc gcgaagagct cttgactctt tggaaagaaa gcagcgcaaa
    11821 tctcctcaag gcttatgatt tctctgatga agaaattgaa gacttgctag aaaaaagact
    11881 tgaattggac cgccgagttg cgacagtggt gctctctaat gaagaaagtt cagaatatgc
    11941 taaactctat catccatatt cttacgaaga tttcaagaaa ttcgcgcctg ccctaccttt
    12001 ggatgacttc ttcaaagcag ttattgggca attaccagac aaggttattg tagacgagga
    12061 acgtttctgg caagcagcag agcaattcta cagtgaggaa gcctggtctc tccttaaagc
    12121 aaccttgatt ttgagtgttg tcaatctttc aaccagctat ttaacagagg atatccgtgt
    12181 tttgtctggt gcctacagcc gtgccctttc tggagttcca gaggcaaaag ataaggtcaa
    12241 agcagcttat catctagcac aggaaccttt caagcaagcc ctggggcttt ggtacgcccg
    12301 tgagaagttc tctccagaag ccaaggcgga tgtggagaaa aaagtggcaa ccatgattga
    12361 tgtctataag gagcgtctgc ttaagaatga ctggctcact ccagaaacct gtaaacaggc
    12421 tatcgtgaag ctcaatgtga tcaaacctta tattggctat ccagaagaat tgcctgcacg
    12481 ttacaaggat aaggtagtga atgaaactgc cagtcttttt gagaatgctc tagcctttgc
    12541 gcgtgtggaa atcaagcaca gttggagtaa gtggaaccag cctgtagact ataaggaatg
    12601 gggcatgcct gctcatatgg tcaatgccta ctacaatcct cagaagaacc tgattgtctt
    12661 tccagcggcc attttacagg cgcctttcta tgacttgcat cagtcatctt ctgctaacta
    12721 cggtggtatt ggggcagtga ttgcccatga aatttcccac gcctttgata ctaacggggc
    12781 ttcctttgac gaaaatggta gcctcaagga ttggtggaca gagagcgact atgctgcctt
    12841 caaggagaaa acacaaaaag tcattgacca atttgatgga caggattctt atggagcaac
    12901 cattaacggt aaattgactg tatcagaaaa cgtggctgac ttgggaggaa tcgcagcagc
    12961 gcttgaagca gctaagagag aagcagactt ctcagcagaa gagttcttct acaacttcgg
    13021 tcgcatctgg cgcatgaaag gtcgtccaga atttatgaaa cttttggcta gcgtcgatgt
    13081 gcacgcacca gccaaactcc gtgtcaatgt gcaagtacca aacttcgacg atttctttac
    13141 aacctatgat gtcaaagaag gagacggaat gtggcgttca ccagaggagc gcgtgattat
    13201 ttggtaatac aaaaaatcta gtcatcagaa aaaaggcatc caatcacgtg tgaaaacctt
    13261 gataggatgc cttttgtaat agaaagattt gctggatagt ttacttaaat ttcgattgtc
    13321 atcatcttgc tagaaaaagg gattgaaggc cttttcgtga gcgatagtag tagctggacc
    13381 atgtcctgga tagacatcgt agtttggtag ggtgaagagt tgggtctgga tactatgaag
    13441 gagttgctcc atgctaccag tcggaaggtc ggtccgtccg atagtttcgc ggaatagagc
    13501 atctcccgtc aagactaggt gagcatcagg aaagactagg gaaacaccac cgatagagtg
    13561 ccctggggtc ggtagaacct taaaacgaaa ttcctctagt tggtattctt cgtgaaagac
    13621 aaaggtgtgt tctgcaggtt ttgtgaccac atctgccata tcatcgtggc gagggagacc
    13681 ggagagatta tcgacaggag tgtagagcca gctggcttcg ctctctgcga tatagacagg
    13741 aggattgcca aacgtctcgc gaaccaagtc cagactcatg atatggtcat aatgggcgtg
    13801 ggtcaagaga atagcacaga tcggtttgtt gatcttctcg attgtctgac gaatggcttc
    13861 ccaatgacta ccaggatcga cgacgatgag gtgcttttcg ccttctagat aataggtatt
    13921 ttcataggca acaggattca cggttttatg gattttcata ctagctccaa tctcaaagaa
    13981 tgtactaata ctcttcgaaa atctcttcaa accgcgtcaa ctttatctgc aacctcaaag
    14041 cagtgctttg aacagcctgc ggctagcttt ctagtttgct ctttgatttt cattgagtat
    14101 aaattaagta tagcacagtt agggagaata ggtaaggatt taaaatgaac ttaaaaacca
    14161 gcatgactag atgaagacag gctggttatc aatttatcaa tattggaaag gtgtcaattg
    14221 cccttcatag gttgcataaa ctccgtcatt agcttgtttg atagacgtga tgtttagagt
    14281 gctaccgtag ttggcttctc atttgtcgct atattcacta taagttatcc tactgggcag
    14341 gttctggtcg ttagcatagt attgaacgac tgttttttat agttttgctg gctgaatagg
    14401 aacaggcagc aaactcctaa cattaggaga gcaaagatag aaatagcagt ttttttcata
    14461 ggtattctcc ttataaacta aaggatagaa gaaagtatct tgaggatttt tatactcttc
    14521 aaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat atatgtgact gactttgtca
    14581 gtcttatcta caacctcaaa gcagtgcttt gaacagcctg cggctagttt cctagtttgc
    14641 tcttggattt tcattgagta ttaattccaa aatccagtca aggtaccagt gtatgtgata
    14701 cgagttccac cgtttatctt tcgtatcttc aatggaattg gggaaatcag aaagtctttg
    14761 ggttacaata tggtttccgt tcttctatct ctccttctat cacctaagtt taaaatctaa
    14821 cttcgtagta tattatgggc caataattca gaattatcaa gcaattttga attatttttt
    14881 tcttattctg ttccaatcta gttttcatat tcttaaaaaa gtgataaaat ggtaggaaga
    14941 attggagagt agagatgccg aaagaagtga atttaacagg cgaagaagtt gtcgctttaa
    15001 ccaaagaata tttaacggaa gaggatgttc attttgtcca taaggccttg gtctatgctg
    15061 ttgaatgcca cagtggtcaa tatcgcaaat caggcgagcc ttatatcatt caccctatcc
    15121 aagtggcagg tattttagct aagctaaagc tggatgctgt aacagtagct tgtggattct
    15181 tgcatgatgt ggtggaagat acagatgcga ccttggacga tttggaaaga gagtttggtc
    15241 ctgatgtgcg ggtgattgtt gacggagtta ccaagcttgg caaggtcgag tacaaatcga
    15301 tcgaggagca attagcggaa aatcatcgca agatgctcat ggccatgtct gaggacatcc
    15361 gcgttatttt ggtcaaactg tctgaccgct tgcacaatat gcggaccctg aaacatcttc
    15421 gaaaagacaa gcaggagcgt atttccaaag aaaccatgga aatctatgcc ccacttgccc
    15481 atcgtttggg gatttccagt gtcaaatggg aattagaaga cttgtctttc cgttatctca
    15541 atccaacgga gttttacaag attacccata tgatgaagga aaagcgcagg gagcgtgagg
    15601 ccttggtgga tgaggtagtc acaaaattag aggagtatac gacagaacgt cacttgaaag
    15661 ggaagattta tggtcgtccc aagcatattt actcaatttt ccgcaaaatg caggacaaga
    15721 gaaaacggtt tgaggaaatc tatgatctga ttgctattcg ttgtatttta gatacccaaa
    15781 gtgatgttta tgccatgctt ggttacgtgc atgaattttg gaaaccgatg ccaggtcgct
    15841 tcaaagacta tattgccaac cgcaaggcca atggttatca gtctatccat acgactgttt
    15901 atggaccaaa agggccgatt gaattccaga ttcgaaccaa ggaaatgcac gaggtggctg
    15961 agtacggggt tgcggctcac tgggcttata agaaaggtat aaaggggcaa gttaacagca
    16021 aggaatcagc tattggaatg aactggatca aggagatgat ggagctccaa gaccaggctg
    16081 atgatgctaa ggaatttgtg gactctgtta aggaaaacta tttggctgag gagatttacg
    16141 tttttacccc agatggagct gtccgttccc ttcccaaaga ttcaggaccg attgattttg
    16201 cctacgaaat ccataccaag gtcggtgaaa aagcaactgg tgccaaggtc aatggccgca
    16261 tggttccact gacaaccaag ttaaagacag gggatcaggt tgaaattatc gccaacccga
    16321 actcctttgg acctagccgt gactggctca atatggtcaa gactagcaag gcgcgcaata
    16381 agattcgcca gttctttaaa aaccaagata aggaattgtc tgtcaacaag ggtcgtgaga
    16441 tgctgatggc tcagttccaa gaaaatggct atgtggcaaa taaatttatg gacaagcgcc
    16501 acatggatca agttctgcaa aagaccagtt acaagacaga agactccctc tttgcggcca
    16561 ttggttttgg ggaaatcggt gcgattaccg tctttaaccg tctgactgaa aaggagcgcc
    16621 gtgaggaaga gcgtgccaag gccaaggctg aggcagagga gcttgtcaaa ggtggcgagg
    16681 tcaaggttga aaataaagaa actctcaagg tcaagcatga ggggggagtg gttattgaag
    16741 gtgcttctgg tctcctagtg cggattgcta agtgttgtaa ccccgtgcct ggtgacgata
    16801 ttgttggcta cattaccaag ggtcgtggtg tggctattca ccgtgtggac tgtatgaacc
    16861 tgcgtgccca agaaaactac gagcaacgtc tccttgatgt ggaatgggaa gaccagtact
    16921 ctagctcaaa taaggagtat atggcccata tcgatatcta cggtctcaac cgtacaggac
    16981 tgttgaacga tgtactgcaa gttctttcaa atacaaccaa gaatatttca acggtcaatg
    17041 cccaaccaac caaggatatg aagtttgcta atatccatgt gtccttcggt attgccaacc
    17101 tctctacact gactacggtt gtcgataaaa ttaagagtgt gccagaagtt tactctgtca
    17161 aacggaccaa cggctagttg tcctagctct tactagaaag gctattatga aaatcattat
    17221 ccaacgggtt aaaaaagccc aagtgagtat agaaggccag attcagggaa aaatcaatca
    17281 gggactttta ttgctggttg gtgttggacc agaggaccaa gaggaagatt tggactatgc
    17341 tgtgagaaaa ctggtcaata tgcgaatttt ttcagacgca gaaggcaaga tgaacctatc
    17401 tgtcaaagat attgaaggag aaatcctctc tatttctcag tttaccctct ttgcggatac
    17461 taagaaaggc aatcgtccag cctttacagg ggtagctaaa cctgatatgg catcagactt
    17521 ctatgatgct ttcaatcaaa aattagcgca agaagtgccc gttcagacag gtatctttgg
    17581 agcaaatatg caggttgagc tggttaataa cggacctgtt accattatcc tagatactaa
    17641 aaagagataa gaaagaccaa gcccagtcgg cttggtcttt ctcatctatc ataaaatact
    17701 ccaaaaagaa atcggttctt gatatgcttg ggggaagtct cttttcaggc tttggcagat
    17761 gcgataggaa gggatgagat gtcctaggat gaggagagtt ccctgaagga aaagtggaat
    17821 atcacttaaa gacaccaagg agagaatcat caggctatcc cataggagaa tttgtaaagc
    17881 aaaacgccag aatctcggtc taatctggga atagagttga ctaaagtggt cacaaagttg
    17941 gtttgaaaga taggtcaata gcacaggatg aaagaaaatg agccaaccgc tataaatcaa
    18001 aatccagtcc caagtaagcc ccccttttta aatgtcaaaa atgccagcat gattccatca
    18061 atgacaagga gttgaatggt tttgatgaag atgatttttt tcatgctaaa acctcctttt
    18121 ccttagagac actcccctac aggtatttta gaatgtatat tg
//
LOCUS       DAVLZG010000044        17702 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLZG010000044 DAVLZG010000000
VERSION     DAVLZG010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.044"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            1..1273
                     /locus_tag="VYO72_001455"
                     /pseudo
     CDS             1..1273
                     /locus_tag="VYO72_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1413..1706)
                     /gene="rpmA"
                     /locus_tag="VYO72_001456"
     CDS             complement(1413..1706)
                     /gene="rpmA"
                     /locus_tag="VYO72_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1707806.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(1723..2067)
                     /locus_tag="VYO72_001457"
     CDS             complement(1723..2067)
                     /locus_tag="VYO72_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1707807.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(2083..2397)
                     /gene="rplU"
                     /locus_tag="VYO72_001458"
     CDS             complement(2083..2397)
                     /gene="rplU"
                     /locus_tag="VYO72_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1707808.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEADQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(2433..2520)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(2615..3214)
                     /locus_tag="VYO72_001459"
     CDS             complement(2615..3214)
                     /locus_tag="VYO72_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1707809.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            3684..3983
                     /locus_tag="VYO72_001460"
     CDS             3684..3983
                     /locus_tag="VYO72_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1707810.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            4202..5279
                     /locus_tag="VYO72_001461"
                     /pseudo
     CDS             4202..5279
                     /locus_tag="VYO72_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5595..6569)
                     /gene="pta"
                     /locus_tag="VYO72_001462"
     CDS             complement(5595..6569)
                     /gene="pta"
                     /locus_tag="VYO72_001462"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1707811.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(6613..7509)
                     /locus_tag="VYO72_001463"
     CDS             complement(6613..7509)
                     /locus_tag="VYO72_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1707812.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(7506..8324)
                     /locus_tag="VYO72_001464"
     CDS             complement(7506..8324)
                     /locus_tag="VYO72_001464"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1707813.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(8308..8979)
                     /locus_tag="VYO72_001465"
     CDS             complement(8308..8979)
                     /locus_tag="VYO72_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1707814.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9107..9676
                     /locus_tag="VYO72_001466"
     CDS             9107..9676
                     /locus_tag="VYO72_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1707815.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            9789..10748
                     /locus_tag="VYO72_001467"
     CDS             9789..10748
                     /locus_tag="VYO72_001467"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1707816.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            10758..11873
                     /locus_tag="VYO72_001468"
     CDS             10758..11873
                     /locus_tag="VYO72_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1707817.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            11878..12225
                     /locus_tag="VYO72_001469"
     CDS             11878..12225
                     /locus_tag="VYO72_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1707818.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            12233..12448
                     /locus_tag="VYO72_001470"
     CDS             12233..12448
                     /locus_tag="VYO72_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1707819.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            12531..13172
                     /locus_tag="VYO72_001471"
     CDS             12531..13172
                     /locus_tag="VYO72_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1707820.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            13190..13879
                     /locus_tag="VYO72_001472"
     CDS             13190..13879
                     /locus_tag="VYO72_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1707821.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(13876..14556)
                     /gene="radC"
                     /locus_tag="VYO72_001473"
     CDS             complement(13876..14556)
                     /gene="radC"
                     /locus_tag="VYO72_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1707822.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(14599..16890)
                     /gene="pcrA"
                     /locus_tag="VYO72_001474"
     CDS             complement(14599..16890)
                     /gene="pcrA"
                     /locus_tag="VYO72_001474"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1707823.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(17082..17702)
                     /locus_tag="VYO72_001475"
                     /pseudo
     CDS             complement(17082..17702)
                     /locus_tag="VYO72_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT         5448 a         3784 c         3251 g         5219 t
ORIGIN      
        1 acattaaaga ccctaatatc cagattttag acatcatcaa taaggataca cacaaggaaa
       61 tcatcgccaa actggactac gacgccccat cttgccctga gtgcggaaat caattgaaga
      121 aatatgactt tcaaaaacct tctaaaattc cttatcttga aacgactggt atgcctacta
      181 gaattctcct tagaaagcgt cgtttcaagt gctatcactg ttcaagaatg atggtcgctg
      241 aaacttctat cgtcaagaag aatcaccaaa ttcctcgtat tatcaaccaa aaaattgcgc
      301 aaaagttgat tgagaagatt tctatgaccg acattgatca tcagttgtct atttcaactt
      361 caactgtcat tcgcaagatc aatgattttc actttaaaca tgatttttct tgtcttcctg
      421 agattatgtc ttgggatgag tatgccttca ctaagggaaa gatgagtttc attgcgcaag
      481 attttgataa tcttaatatt atcactgttc ttgaaggcag aacacaagct gtcatccgaa
      541 atcactttct tcgctacgat agagccgttc gttgtcaagt gaaaatcatt acgatggata
      601 tgtttagtcc ttactatgac ttggctaaac agcttcgctt tcaaatttct aggctcaggc
      661 tgaaacagtc tcccagactg tttcactccc gaatgctaaa atcgttcttg atcgctttca
      721 cattgtgcaa catcttagcc gtgctatgag tcgtgtgcgt gttcaaatca tgaatcagtt
      781 tcatcgaaaa tcccatgaat acaaggctat caagcgctac tggaaactca ttcaacagga
      841 tagccgtaaa ctgagtgata aacgttttta tcgtcctact tttcgcatac acttaacaaa
      901 taaagaaatt cttgacaaga ttttaagcta ttcagaagac ttgaaacacc actatcagat
      961 ctatcaactc ttactttttc actttcagaa caaagaccct gagaaatttt tcggactcat
     1021 tgaggacaat ctgaagcagg ttcatcctat ttttcagact gtctttaaaa cctttctaaa
     1081 gaacaaagaa aaaatcgtca acgctcttca attaccttat tccaacgcaa aattggaagc
     1141 gaccaataat ctcatcaaac ttatcaaacg aaacgccttt ggatttcgga actttgaaaa
     1201 cttcaaaaaa aggattttta tcgctctgaa catcaaaaaa gaaaggacga attttgtcct
     1261 ttctcgagct tagctgactt caacccacta cagttgacaa agagcctaaa aaaacaggct
     1321 ctccgaaaac tcggaaagcc ttattttaag ctgtttctag cttcctcacc tttatatttc
     1381 aaggttcggg ataaaaggtt caatggacct ttttatttag cgattgggta aacagaaact
     1441 tgttttttat cgcgtccttt acgttcaaag cgtactacgc cttcaacttt agcgaacaaa
     1501 gtatcgtctc caccacgacc aacgtttaca cctggataga tgtgtgtacc acgttgacgg
     1561 taaaggattg atccacctgt tacagtttgt ccgtcagctg ctttagctcc aagacgtttc
     1621 gcttgtgaat cacgtccgtt tgatgtagaa cctccacctt ttttgtgggc gaaaagttgc
     1681 aagttgttaa gagtcatttt taacataatg ttttcctccg tgttagtttt ctgtgataac
     1741 tctggtttgg acgaactcag aagagttctc cgataagttt gccataccta agaaaaatga
     1801 ttcaaagaat aactgggtca tttctctctg gtgtgaagga agatcttttg gtatttcaac
     1861 catcagatag ccaccttcat cttcgtttaa ttctaggatt ggttcatagc ctgcaaattt
     1921 ctcaatagaa ttgataaagt taatggcaag cgtagaaacc gatgcacaca cgacatctaa
     1981 gccgtattcg ccactctcgg cgtgtccagt aatttccgca ctcctcagct cgccatcttc
     2041 ggctctctca aagactgcct gtatcatgtg ttctccttaa aattaagcgt tgattgcgtt
     2101 gatgacaact tttgtatatg gttgacggtg accttgttta cggtggctac cttttttagg
     2161 tttgtacttg taagtaacca ctttcttttg ttttccttgt ttttcaacag ttccaactac
     2221 agtagctcca gcaacaagtg gagttccgac aacagtgttt tcaccaccaa caagaacaac
     2281 ttcgttaaaa gtaacttctt gatcagcttc aacgttcaat ttttcaacgt aaactgcttg
     2341 accaacttca actttaactt gttttccgcc agttttgata attgcgtatg tgctcattat
     2401 gcacctccta tgatttttat gggtttcccc gattttttgt gaagactcgc ctagcatcgt
     2461 gggacgaacc acttaaactt gaataatcaa gcaacgatgt tcgtgcggtt gcacaggatc
     2521 gtgcatagtc aactcttcaa gtatagcata tctcctattt tcttacaagt aataacacct
     2581 aaaatgaagc tttttctttt acttttttct gccactaggc aaaaagcata ctgagataaa
     2641 aaatgctcat cataatagga acaccaagaa tggtcttttc atgatagaaa atcgtcaaat
     2701 aggctgaaaa gacatcgcca aggacaaaac tactaagcag gctaacaaat atgaaccctt
     2761 cacgcaaaaa aggagtgtgc ttagttcgga aataatctcc aaaagctagc attgttcgtt
     2821 tgatattccc tgtcataaag gcattattgt aggcaatacc cgaaacctca ccaaaagcag
     2881 ttgtcaccag tcccatacag aaggccaagg gctgcactag atagatatta tctacagttt
     2941 gtggcacaaa accaataatt attgatagga ttgctaaagg aatcaaggac agaataggtt
     3001 ttttcacaat tctcaatttt tccttataaa tcgttaataa aaagactccc attataaacg
     3061 ttattaaggt taaaagctta tccctaacat ccgaaacatt attttgtatt agctctaccg
     3121 aaagaaagac aacatttcca gcttgtccag ctacaagggt attccctcga acaataaaag
     3181 tgtaagcatc cacatatcca gcacaaaatg tcaaaaaagt gctaaccttt tagactgacg
     3241 tgatattttt cttataggta ataacctcat tttccctccc attgtatttt ctcttagaaa
     3301 tattgtacca tttctttcta aaaaatcgta gactaccatt tagattttac tattagcata
     3361 aaaataataa tagacaacta tttatccaaa aatagataga ggtaacatgt ttgcaaacaa
     3421 agcatacgaa cctttagtaa aatcatttcc atgaaactag aatagagccc ctcttagcaa
     3481 aaatcattat tttaatttat ttctaatcac tccttgacat aaataactct caccaataaa
     3541 agactatgtc ttaaaaaaat ggtataataa aatcaatacc tgggcttgat ggctatgcta
     3601 ctaataacaa ttaggagaga aaatcaggca cttgttaaca acaaggatta tccccttgag
     3661 atgaaaggaa ctttagaaat cttatgatga acatgcaaaa catgatgcgt caagcacaaa
     3721 aacttcaaaa acaaatggaa caaagccaag ctgaacttgc tgctatgcaa tttgttggca
     3781 aatctgctca agatcttgtc caagcgacct taactggcga taagaaagtt gtcagcattg
     3841 atttcaatcc agctgtcgtt gacccagagg accttgagac tctttctgat atgaccgttc
     3901 aagccatcaa ctctgctctt gaacaaatcg atgaaactac taagaaaaaa ctgggtgctt
     3961 tcgctgggaa attgccattc taaaaacaag gagctagaac aatacttgtc gataacaaag
     4021 gctaagaaag gtgcaaaaat tataaaaaac gcatagtatc aagcaaccta aaactttggg
     4081 ctctataata tttgtagtgg gtaaatccac tatagatatt atggagccta ttttattgta
     4141 gaaaaaaatc ccataagatc tataatgaaa agcgaccaaa caactcatta gaaagattca
     4201 tatgggacaa ttacatttta tcacaaaatt actagacatt aaagacccta atatccagat
     4261 tttagacatc atcaataagg atacacacaa ggaaatcatc gccaaactgg actacgacgc
     4321 cccatcttgc cctgagtgcg gaagtcaaat gaagaaatat gactttcaaa aaccgtctaa
     4381 gattccttac cttgagacaa ctggtatgcc tactagaatc ctccttagaa agcgtcgatt
     4441 caagtgctat cactgttcaa aaatgatggt cgctgaaact tctatcgtca agaagaatca
     4501 ccaaatccct cgtatcatca accaaaagat tgctcaaaag ttaattgaaa agatttctat
     4561 gactgatatt gcccatcagc tttccatctc aacttcaact gttattcgta agctcaatga
     4621 ttttcacttt gagcatgatt tttcgcgtct tcctgagatt atgtcttggg acgttgaaac
     4681 agtccgggga gtgactgttt caatcgggag atggagatga gctttattgc tcaggacttt
     4741 gataagctca atatcataac tgttcttgag agcagaacac aagccatcat ccgaaatccc
     4801 atgaatacaa ggctatcaag cgctactgga aactcattca acaggatagc cgtaaactga
     4861 gtgataagcg attttatcgt cctacttttc gtatgcattt aaccaataaa gagattttag
     4921 acaagctttt gagctattca caagacttga aacatcacta tcagctctat caactcttgc
     4981 tgtttcactt tcagaataag gaaccggaga aatttttcgg actcattgag gacaatctaa
     5041 agcaggttca tcctcttttt cagactgtct ttaaaacctt tctaaaggac aaagagaaaa
     5101 tcgtcaacgc ccttcaacta ccctattcaa acgccaaatt ggaagcgacc aataatctca
     5161 tcaaacttat caagcgcaat gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga
     5221 tttttaccgc tctgaatatc aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc
     5281 ttttcttcaa cccactacag ttgacaaaga gccagaaaac gcataatagc aggtgtcaag
     5341 acacttaata ttatgcgttt tctcatgaaa aaattctctt ttcatactca tttaaaatca
     5401 aaaagggaaa ttatcgtttt acggacatac atattacaga tttctatagg tcgtgtatag
     5461 acaggatatc atcgcttgga agttttcctt tttgacacca atcagtaatt tagttctcag
     5521 gaattaatgg cagtgctttt cgtacatagt ttcataacta cagtatagca tagtatatcg
     5581 ctttatagtt ttcactattg atgaactgct tgagctgctg tgatgagggt caacttgtaa
     5641 acatcatctg cattacatcc acgagaaaga tcattaactg gcttgtttaa accttgcaaa
     5701 acaggtccta cagccgcaaa gccacccagg cgttcagcca tcttgtaacc gatatttccg
     5761 gcctcgatac ctgggaagat gaagacattt gcttgaccag ctaccgtact tccaggagct
     5821 ttcagagctg cagtttcagg aacaaaggct gcatcaaatt gcaactcacc atcgatttca
     5881 aggtcaggac gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc aacgctttca
     5941 ccaaaccctg aacctttagt agaatagctc aacatggcaa ttttaggttc gatgccaaac
     6001 atcttagctg tgattgctga gttgatggca atttcagcca aggcttctgc atctggattg
     6061 atgttaatgg cacagtctcc aaataggtaa cgttccgtac cacgaaccat gaggaaggct
     6121 cctgaagtac gagttacatt tggacgagtt ttgatgattt gtagagctgg acgaactgtt
     6181 gaagctgttg agtgaatcgc tcctgacacc attccatcaa ccaagcccaa gtaaaccaac
     6241 atcacaccaa agtagttgac atcttcaacc aaaaccttgc gtacatcttc ttcagtcatt
     6301 ttgcccttgc gacgctccac caaggcagaa accatttctt caaattgagg ataatgttga
     6361 gggtcgatga cctcataacc atccatgatt ccttcaattt caagataaat tttaattttt
     6421 tcaggatttc caagcaaaac aggaatcact tctgtttctt ttactaagcg ttttgttgct
     6481 tgaagaatac gaggctcttc cccttcaggg agaacgatac gagcattttt accaacaagg
     6541 ttggctttga gactttcaaa aacttccatg agttttctcc tttaagataa taattatact
     6601 ctgagacagt ttttatagag tattagttga taactgggta ataaggttac tgaaatcatc
     6661 cggcaaggga ctttctaact gcaagtcttg ctctaaaaat ggatgataaa aggataggta
     6721 atggcaatgc agagcctgac gttgaatacc atcttccaga ctaccaccat acaaatcatc
     6781 tcccagcaaa ggaaaaccga tatgagaaaa atggactcgg atttgatggg ttcgaccagt
     6841 gtgcaggtga atatagacca agtgaatatt tccataagaa gctacaatct tgtatgaagt
     6901 atgggcatac tttccgcctt tagccactcg tctggtaata atggaatctt catcacgcgc
     6961 aatcggagca ataatttccc cttctggctc caaatgtcca tctcccttaa ccaaagcaaa
     7021 gtagcgtttc tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat gggcataacc
     7081 gtgcttggca aagagcatca agccagaagt gtccctatct agtctggtaa caatgtgaac
     7141 ctgctgattt tcataatttt gcttgacata gtaacccttg ataaaattgg caatggtgtt
     7201 agagtgattg acactaggaa tagaagccac tccatagggt ttattcaaga ctagaaagtg
     7261 gtcatcctca tagagaatat ctaatggatg ctcaatagcc tccaaggttt caaagccttc
     7321 ctcagcggga atgtcaatgg taacgtagtc tccaacgtcc aatagatacg ttgcattttg
     7381 cggttgatta ttgaccagaa tagctccacc tcgaaactta atcttagcca gcaatccctt
     7441 agaaacctcg tgctttttta aaaaggtctt aaccttgaca tgttcatctg cgataaattc
     7501 aaacctcatt catccacctc accgataaag gcatccttaa cacggttcca gaaactggta
     7561 tggctaggag tcgcgacaaa gtgaatctta tgatggtcga tttgatactc aatacgctca
     7621 atattacgga aagaataaac gctattgtca accgaaatag tatgataatc gtttcttgtt
     7681 ggaataagtt caatcttatc cttcttaggc acaataatgg aagagcccag tgttcgataa
     7741 acacgattat taaggctggc aatttccgtt aattgcaaag cttcaatggt agggtgtaaa
     7801 acagcaccgc caagagactt gttataggca gtactaccag tcggtgtcga aactgttagc
     7861 ccgtctccac gaaaacgttc aaagggaaca ccatttatta caatatctgc caccatggtt
     7921 cgatcagacc tgcggatgct ggcttcgttg agtgctctga aaatcttaac ttcaccattt
     7981 tcaagaaaga ccttcacatt cagaacaggg taagaaaccc ttgccccagt atctagctgc
     8041 aaattagtca ctagcttgtc caactcaaaa tcacgataat ctgtatagaa gcccaaatgt
     8101 ccagtatgaa gaccgataaa gcggaccttg tcaagctgat tttcgtactt atgaaaggcc
     8161 gacaagagca taccatcccc gccaatggaa atgacaatat ccggattggt atcattgagt
     8221 ataaactgat ttctcttcaa acgatctcgc aattcataca aaaccctttg actctgcggt
     8281 tttctattgg ctatcagatc aattcgttta cctgtattct tcatctgtat cgtcactgtt
     8341 tcctacaccg tcatttaatt ttctactcaa aggatcaaaa agtgcctggg cttcttggat
     8401 atcatcacga atttcaccca tttcttcatc caactgatgg gcgattctag ctgtaatttc
     8461 cagtcgcttc ttaatctcat ctgggaaatc cccttggtac ttgtagttga gagaatgttc
     8521 tatcgttgcc cagaaattca tggccaaagt acgaatttga atttctgcca aaatagtctt
     8581 agctccattg atggtatcaa ccgtatattc tactaccaca tgataggaac gatagcctga
     8641 tgcttttcta tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct gacgcttgtg
     8701 caaaatatcc actacttcct tgacgtcatc tacaaactga accatcacac gtaagccagc
     8761 aatatcctgc aaatcgtgtt ccaaggtcgc ataagtaatg ccacgacgag ccattttttc
     8821 tttgatgctc tcaattggct tgactcgacc ggtcacaaac tcaattggag aatgcttatt
     8881 ttgcttacga tattgcttac gaataccacg aagtttaatc tttaactcac caacagcttg
     8941 aatgtaagga tctagaaatt cttcccattc taaggtcata tattctccct tgttctcata
     9001 ttatccgtca aaaatatctt tgattttttc tccagattca tatacaataa atacaatgct
     9061 tattatacca taaatccgct ttcaacgata aaaaaaggta agaaaaatga aacatttaga
     9121 aattgaattg aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag accagttcac
     9181 aggtgtcact cctgttcttc aaacaaatta ctacatcgac acgcctgatt ttgaactgcg
     9241 agaaaagaaa gtcgctatgc gcattcgaac ctttgaagac tgggctgagt tgacactcaa
     9301 agtcccgcag agtgttggaa acatggaata caaccaaaaa ttgcaactaa aagatgctga
     9361 ggactatctg agtaaggaag aacttcctca aggactagta ctggatgaat tggcgaaaca
     9421 tggtatccaa agtaagaact ggcaggttct tggttgtcta acaacgcttc gctatgaaat
     9481 gaaaacagct attggtctca tggcactgga tcagagccga tactttgata taacagatta
     9541 cgaattggag cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc gacaattttt
     9601 agagaaaaat cagatttcct accaaaaagc tccttcaaaa ttggttcgat ttgtcaaaag
     9661 tatgaaaaat agctgaaata atctccattt tttggtaaaa tagaaaagat aaaaatacac
     9721 aaatcccagt tcatatatgt aaggtaaata taactaggat ttataaagtt tacagaggac
     9781 ggtctataat gtcagataga aaaaacatga aacttttcgc actcaactct aaccaagaga
     9841 ttgcacaaaa aattgcccaa gctgttggtg tcccacttgg aaaactatca tcacgtcaat
     9901 tttcagacgg agaaatccaa gtaaatatcg aagaaagtgt ccgtggttat gatgtttaca
     9961 tcatccaatc aacaagtttc cctgtcaaca accacctaat ggaattgtta atcatggtcg
    10021 atgcttgtgt gcgtgcaagt gcccacagta tcaacgttgt ccttccatat tttggctatg
    10081 cacgtcaaga ccgcattgct tgtcctcgtg agccacttac agcaaaacta gttgccaata
    10141 tgctggttaa ggctggagtt gatcgtatcc tgactcttga tttgcatgcc gttcaggttc
    10201 aaggtttctt tgatattcca gtggataatc ttttcactgt tcccctattc gcaaaacatt
    10261 actgcgataa aggattgctt ggttcagatg ttgttgtcgt tagccctaaa aattcaggtg
    10321 tcaaacgtgc gcgtagcctg gctgaatatc ttgatgctcc tatcgccatt atcgactacc
    10381 ctcaagacga tgcaactcgt aacgaaggtt atattattgg tgatgttgaa ggtaagaaag
    10441 ctatcttgat tgatgatatt ttaaatacag gacgtacctt ctctgaagct tctaaaatcg
    10501 ttgaacgtga aggagctaca gaaatttatg ctgtttctag ccacggtctc ttcgtcgagg
    10561 gagctgctga gcttcttgac aatactaata ttaaagaaat tcttgtgact gattcagtag
    10621 caacaaaaga aaaaactcct aaaaatgtat gctacatcac tgctagtgag ttaattggtg
    10681 atgctatcgt ccgtattcac gaaagaaaac cagtcagccc actctttgcc tacaataaaa
    10741 agaaataagg tgattctttg atttatttgg acaatgctgc aacgactcct atgtcagcag
    10801 ttgctatttc agctatgacc aaggttatgc aagaaaccca cggaaatcct tctagtattc
    10861 atggtcatgg tcgtcaagct ggcaaactct tgcgagaagc ccgtcaggaa ctagcccagt
    10921 tactaaggac aaaacctcaa catatctttt tcacttctgg tgggactgaa ggcaataata
    10981 ctaccatcat tggctactgt cttcgtcacc aagaacaagg aaaacatatc atcacaactg
    11041 ccatcgagca ccatgctgtc cttgaaacaa ttgattactt ggttcaacac tttgggtttg
    11101 aagcaaccat tatccagcca gaaaatcaag aaatcacagc ccagcaaatt caaaaggctt
    11161 tacgtgacga tacgattttg gtttctacca tgtttgccaa taatgagaca ggaaacctac
    11221 tgcccatcgc tgaaattggc caaatactca agcaacaccc tgctgcctat catgttgatg
    11281 cagttcaggc tattggtaaa atcccaattc attcagaaga attgggcatt gattttctca
    11341 ctgcttctgc ccacaaattc catggtccta agggaatcgg ttttctctac gcatctagca
    11401 tggactttga ttcctatcta catggcggag accaggaaca gaaaaaacgt gcaggaactg
    11461 aaaatctgcc tgctatcgta ggcatggttg cagccctaaa agaagaccta gaaaaacaag
    11521 aagaacattt tcaacatgta caaaatctag aaaccgcctt tctggcagag ctggagggca
    11581 ttcagtatta cctgaataga ggaaaacatc atctccctta tgttctcaat attggatttc
    11641 ctggtcagaa aaatgacctc ttactccttc ggctagattt agctggaatt tcaatctcta
    11701 ctggctcagc ctgtactgca ggcgttgtcc aatccagcca tgttcttgaa gccatgtatg
    11761 gcgcaaattc agaacgcttg aaggaatccc ttcgcatcag tttgtcgcca caaaataccg
    11821 ttgaagacct acaaaccctc gcaaaaacct taaaagaaat tatcggaggt tagccatatg
    11881 gcatttgaaa aaatcattca gttaaaaaat tgtcgttacg attacactct tagcccttct
    11941 gttaaaaaat tcaccctcaa agataacacc ttttttgaaa ctaaggttgg taactatgaa
    12001 ctgactcgcc ttttggaaaa agtgccaaac agcggtgaag gcttccaact caaaatcatc
    12061 attaacaagg aacttacagg ggctaaaatc aatatcactg acaagtttag ccttcgtcta
    12121 gttgatattt tcaaatcaga agaccaccat attcatcagg aaaaattcta cttcctcatg
    12181 gatagcttgg tagaacgtgg tgtctttaca aaatcggaaa gatagagcca aaatgtttga
    12241 actgacctat aaggactgct atcatgtaga gcgtactctc aagtatgagg atcatgaggc
    12301 tctcatgttg actttgtcag gatgtgtaac cttaccagat acactttatg tgacttctct
    12361 gacttttagg ggccaaaaag tttatcaggg tctggtcgga gacctctacc gttttctatc
    12421 tcatgcagat tttttacatc aaaactaaga tttttcttag ttttttctta tttttgttga
    12481 ttttttcaca atgtttctat aaaatagaag aatagaaagg ttgtgatttt gtgaaagata
    12541 aacagtttgc tattccaaaa gctacagcaa aaagactctc tctctactat cgaattttta
    12601 agagatttca tgcagaaaag attgaacgtg ccaactctaa gcaaattgca gaggctatcg
    12661 gtattgattc agcgaccgta cgtcgtgatt tttcctattt tggtgaactt ggtcgtcgtg
    12721 gttttggcta tgatgtcaaa aaactaatga cattttttgc cgatttgctc aatgacaact
    12781 ctattaccaa tgtcatgctg gttggtattg gaaatatggg ccatgccctt ctccactacc
    12841 gcttccacga acgtaacaag atgaagatta tcatggcctt tgacctagac gaccatcctg
    12901 aagtcggtac ccaaactcct gacgggattc ccatttacgg gatttctcag atcaaggata
    12961 aaatcaagga tgctgatgtg aagactgcta tcctaactgt tcccagcgtc aagtcacaag
    13021 aggttgctaa tctcttggtt gatgctggtg tgaaaggaat tctcagtttt tcaccagtcc
    13081 atctgcattt accaaaagac gtggtcgttc agtatgtcga tttgacaagt gaactccaaa
    13141 ccctcctcta cttcatgcga aaagaggatt agaaagcgaa aatcatttta tgaaaaaacc
    13201 agttattggg attacaggaa acgaaaaagc tcatccagat gatgacatca tgatgagcta
    13261 cgcagcaaaa ggctttgttg aaggcgttaa agatgctgga gggattccca tcatcctacc
    13321 gattggtgat caagaaatgg cctgccacta tatcagtttg attgacaagc tcatcttgac
    13381 aggtgggcaa aatgtcgatc caaaatttta tggcgaaccc aaaaccattg atagcgatga
    13441 ctataacctt caaagagata tcttcgaact ggccctcatc aaggaagcta ttaaacagaa
    13501 aaagcccatt ttctctgtct gccgtggtac ccaactcttt aacgttgcca tgggtggaac
    13561 tttgtaccaa gatatcgaag accattggca ggattcttct gttgagtaca caactcaacg
    13621 cttggtaaca gaaccagata ccgttctcca agaaatctat ggagaaatct ctcatatcaa
    13681 ctccttccac caccagagca tcaaggactt agcaccaaat ttaaaagttg tggctcatga
    13741 tcctaaagat ggtatcattg aggctgtcat gagtacggat gatgtcgcct ttctcggtgt
    13801 ccaatggcat ccagaacttc tttttgaaaa tcgtcccaaa gataaaaaac tctttgacta
    13861 tgtcgttaat gaactttaga ttaaatctgt cttttcacga taactaaagt aattagaatg
    13921 agagacaatc aaatggtcca agagaacaat ccccatcaat tcgcaggctt ctttaacaag
    13981 tttagtgaca tgatcatcat tttggctagg cgctaccgct cctgaaggat gattgtggac
    14041 caagataaga gaagtcgcca tatgcttgat tgcatagtga agaatctctc gcggttcagc
    14101 gatactacga gttacagaac cgataaaaat ggtctgctga tggatgattt gattttgagt
    14161 attgagatag agtgccacca ggtgctcttg ttttttatcc cctaattcct gctgcatctt
    14221 cttggccaac ttttgactgc tgagaatact ttccatttca agagtctcgt gtttgtgaat
    14281 acgatgcccc agttcaatca tagcttgtaa ttctatggcc ttaacacgcc caataccaga
    14341 caaactctgc aattcctgca gggtcatttt tttcaaatcc gttaggcttg aaagattgtt
    14401 caagactttt tgggcaattt caaaaacgct agcttgacgt gttcctgtcc tgagtaaaat
    14461 agctagcaac tcttggttac taagcgcttc aactccttcc ttggccagcc tttctcttgg
    14521 taatagtgaa tcttcttgga atgaaatact gtacataaaa atcctcctca ctttattatt
    14581 cgtgagaagg atggaaaatt agattttttt ctcaattgga gccacactgg ctaaaagttt
    14641 tttcaaacct acttctggga aattgatttt caattcctgc ctagcaccgc tacctgaaac
    14701 ttccagaaca gttccctctc cccatttctt gtggagagca atgtcaccaa tggaccaatt
    14761 tgcctcgcta gatgctgatt ttgcgccagc tgtaaattga ccaaatggaa gaccgcttga
    14821 ctggatcgat tttggggcag caccgcgttt acggtcttga agagcctgag ccaaactcat
    14881 accttgacca aaggaaatac taccactgct atatgatgcc ttaaagcttg tatttgcagg
    14941 acgagccaga ccttgatact caagcaagtc tgaactgatt tcgttaataa aacgagtcgg
    15001 acggttataa ttggtacgac caaaaagcaa gcgtgagttg gcattggtca gatagagaat
    15061 tttctctgca cgcgtgatac ctacataggc tagacggcgc tcttcttcta attcatctgg
    15121 atcttcagtc gcacgactaa gtggaaagac attttcttcc atcccaatca aaaagacaac
    15181 tggaaattcg agacctttgg cagcatgcag ggtcatcaag gtcacttctg atgtctcctg
    15241 actacctgaa tctgtgtcgg caatcaaagc caagtcattt aagaaacgac tcagtttgtc
    15301 cagaccagtt tcctcttctg tcacatcagt ggtgtcatca aagttcttcg taacagaaag
    15361 aaactcttcg atattttcaa cccttgcctt gctttctaga gtcgcttggg cgttaagaat
    15421 atcgacataa cctgtttttt ctaggacgga ctcaaccaac tctgtaatgc ttaagtggtc
    15481 tagctgctcc cgcaaatcaa gcatcatatt ggcaaaatcc cagatagatt gggctgcctt
    15541 acccttgata ccagacaaca taatattagc agaagcatcc agcatagaca tattttgcaa
    15601 atttgcaaaa tcacggattt tctcaactgt acctagacca attccacgtt taggctcgtt
    15661 gataatacgc tcaaaactaa tgttgtcact caaattagca ataaggttga gataagcaat
    15721 aatatcgcga atttccttac ggctgtagaa tttggttccg ccaaccatgg tataaggaat
    15781 gttagacttg agcagggctt cctcaattgt acgggactgg gcattagtcc gatagagaac
    15841 tgcaaaatcc ttatgaagga agttttgact gcgactaagt tcatcgatgg ttctggctac
    15901 aaatacagcc tcatccagct catcatcagc acgatagtaa acgatttgct ccccatcagc
    15961 gttttgagtc cagagatttt taggacggcg atttttatta tttttaataa cctcgttggc
    16021 cgcttggaga atggttttgg ttgagcggta attttcctcc aacaaaacaa ccttagcttt
    16081 ggggtaatcc ttttcaaagt ccaagatatt ctgcatatca gcaccacgcc aaccgtagat
    16141 agactggtcc gcatccccaa ccacacagat atttttaaaa cgggaagcca agagtttgac
    16201 caattggtac tgagcgtggt tggtatcttg gtactcatca acgtggatgt attggaattt
    16261 ttgctggtag taggtcaaaa catcaggatt ttgatcaaag agacgcaagg tcagcataat
    16321 caaatcatca aagtcaacgg attcagactg acgaagttct ttttgatagg ttgtataaca
    16381 ctgggccaca atttgcgtat acatatcgcc agcttgagca gcataagcaa catcatcaat
    16441 caaatcattc ttagcattgg aaatggtccc caaaatagtt cgttcattcc attttttagg
    16501 atccaagttc aactgtttga gaatacgttt catgagcgtt cgctgttcac caggatccac
    16561 aattgtaaaa ttacgattgt agccaatatg gtccgcatcg cgacgcaaaa tacgcacaca
    16621 catggagtgg aaggtcgcaa tcagacagtc ctgagtagct ggattgaggc tataagcacg
    16681 ctctttcatc tcacgcgcag ccttgttggt aaaggtaatg gccaagatat tccaaggatt
    16741 gaccagcttt tcatcaatca aataagcgat acggtgggtt aaaacacgag tctttccaga
    16801 accagctcct gccatgatta gcaagggacc ttctgtcgtt tgcaccgcct cagcctgacg
    16861 gtcattcatt ccatttaata atgcgttcat cttctcttcc ttactcttga agtcaatatt
    16921 tctattatat cagaaatcag ggaaaataga aactttacgg ggagtagcaa aatatagtgg
    16981 attgaaacta gaatactaca ctgtgggttt ctaaaacact cgactttttc acccaatttt
    17041 ttcataaact agctcaatac ctcaatagac ttcctgcaaa actagaatcc tagttcatga
    17101 ttgataatgc cagcaatcaa attcattcgt aatccgaagc gtttacgatg atttcgatag
    17161 gttgttgaaa acattttaaa cgtttttact ttggcaaaga tgttctcaac cttgcttctc
    17221 tccttggata gcgcatggtt ataggcttta tcttcagctg ttagcggctt gaatttgctg
    17281 gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata accactgtca
    17341 gccaagattt ttccagcttg tccgatattt ctgcgactca ttttgaacaa cttcatatca
    17401 tgacaatagt tcacagcgat atccaaagaa acaattctcc cttgacttgt gacaatcgct
    17461 tgagccttca tagcgtggca tttcttttta ccagaataat tcgctaattc tttttttagg
    17521 gcgattgatt tttacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
    17581 tcttgaaatc gtaaaaccac tttgaacaag agttacttca acccattggc tccgacggag
    17641 taagttgctt tcgtggatac caaaatcagc cgcaatttgt tcataagttc gatattctcg
    17701 ca
//
LOCUS       DAVLZG010000045        17441 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLZG010000045 DAVLZG010000000
VERSION     DAVLZG010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17441
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.045"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(31..1368)
                     /locus_tag="VYO72_001476"
     CDS             complement(31..1368)
                     /locus_tag="VYO72_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1707824.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(1378..1644)
                     /locus_tag="VYO72_001477"
     CDS             complement(1378..1644)
                     /locus_tag="VYO72_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1707825.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(1909..2295)
                     /gene="rplQ"
                     /locus_tag="VYO72_001478"
     CDS             complement(1909..2295)
                     /gene="rplQ"
                     /locus_tag="VYO72_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1707826.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(2307..3242)
                     /locus_tag="VYO72_001479"
     CDS             complement(2307..3242)
                     /locus_tag="VYO72_001479"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1707827.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(3285..3668)
                     /gene="rpsK"
                     /locus_tag="VYO72_001480"
     CDS             complement(3285..3668)
                     /gene="rpsK"
                     /locus_tag="VYO72_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1707828.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(3686..4051)
                     /gene="rpsM"
                     /locus_tag="VYO72_001481"
     CDS             complement(3686..4051)
                     /gene="rpsM"
                     /locus_tag="VYO72_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1707829.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(4069..4185)
                     /gene="rpmJ"
                     /locus_tag="VYO72_001482"
     CDS             complement(4069..4185)
                     /gene="rpmJ"
                     /locus_tag="VYO72_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1707830.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(4210..4428)
                     /gene="infA"
                     /locus_tag="VYO72_001483"
     CDS             complement(4210..4428)
                     /gene="infA"
                     /locus_tag="VYO72_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1707831.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(4545..5183)
                     /locus_tag="VYO72_001484"
     CDS             complement(4545..5183)
                     /locus_tag="VYO72_001484"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1707832.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(5334..6644)
                     /gene="secY"
                     /locus_tag="VYO72_001485"
     CDS             complement(5334..6644)
                     /gene="secY"
                     /locus_tag="VYO72_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1707833.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(6657..7097)
                     /gene="rplO"
                     /locus_tag="VYO72_001486"
     CDS             complement(6657..7097)
                     /gene="rplO"
                     /locus_tag="VYO72_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1707834.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(7242..7466)
                     /gene="rpmD"
                     /locus_tag="VYO72_001487"
     CDS             complement(7242..7466)
                     /gene="rpmD"
                     /locus_tag="VYO72_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1707835.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(7438..7932)
                     /gene="rpsE"
                     /locus_tag="VYO72_001488"
     CDS             complement(7438..7932)
                     /gene="rpsE"
                     /locus_tag="VYO72_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1707836.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(7950..8306)
                     /gene="rplR"
                     /locus_tag="VYO72_001489"
     CDS             complement(7950..8306)
                     /gene="rplR"
                     /locus_tag="VYO72_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1707837.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(8390..8926)
                     /gene="rplF"
                     /locus_tag="VYO72_001490"
     CDS             complement(8390..8926)
                     /gene="rplF"
                     /locus_tag="VYO72_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1707838.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(9118..9516)
                     /gene="rpsH"
                     /locus_tag="VYO72_001491"
     CDS             complement(9118..9516)
                     /gene="rpsH"
                     /locus_tag="VYO72_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1707839.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(9801..10070)
                     /gene="rpsN"
                     /locus_tag="VYO72_001492"
     CDS             complement(9801..10070)
                     /gene="rpsN"
                     /locus_tag="VYO72_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1707840.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(10088..10630)
                     /gene="rplE"
                     /locus_tag="VYO72_001493"
     CDS             complement(10088..10630)
                     /gene="rplE"
                     /locus_tag="VYO72_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1707841.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(10654..10959)
                     /gene="rplX"
                     /locus_tag="VYO72_001494"
     CDS             complement(10654..10959)
                     /gene="rplX"
                     /locus_tag="VYO72_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1707842.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(11037..11405)
                     /gene="rplN"
                     /locus_tag="VYO72_001495"
     CDS             complement(11037..11405)
                     /gene="rplN"
                     /locus_tag="VYO72_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1707843.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(11431..11691)
                     /gene="rpsQ"
                     /locus_tag="VYO72_001496"
     CDS             complement(11431..11691)
                     /gene="rpsQ"
                     /locus_tag="VYO72_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1707844.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(11716..11922)
                     /locus_tag="VYO72_001497"
     CDS             complement(11716..11922)
                     /locus_tag="VYO72_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1707845.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(11932..12345)
                     /gene="rplP"
                     /locus_tag="VYO72_001498"
     CDS             complement(11932..12345)
                     /gene="rplP"
                     /locus_tag="VYO72_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1707846.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(12349..13002)
                     /gene="rpsC"
                     /locus_tag="VYO72_001499"
     CDS             complement(12349..13002)
                     /gene="rpsC"
                     /locus_tag="VYO72_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1707847.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(13015..13359)
                     /gene="rplV"
                     /locus_tag="VYO72_001500"
     CDS             complement(13015..13359)
                     /gene="rplV"
                     /locus_tag="VYO72_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1707848.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(13371..13652)
                     /gene="rpsS"
                     /locus_tag="VYO72_001501"
     CDS             complement(13371..13652)
                     /gene="rpsS"
                     /locus_tag="VYO72_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1707849.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(13756..14589)
                     /gene="rplB"
                     /locus_tag="VYO72_001502"
     CDS             complement(13756..14589)
                     /gene="rplB"
                     /locus_tag="VYO72_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1707850.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(14607..14903)
                     /locus_tag="VYO72_001503"
     CDS             complement(14607..14903)
                     /locus_tag="VYO72_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1707851.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(14903..15526)
                     /gene="rplD"
                     /locus_tag="VYO72_001504"
     CDS             complement(14903..15526)
                     /gene="rplD"
                     /locus_tag="VYO72_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1707852.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKLVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(15551..16177)
                     /gene="rplC"
                     /locus_tag="VYO72_001505"
     CDS             complement(15551..16177)
                     /gene="rplC"
                     /locus_tag="VYO72_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1707853.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(16394..16702)
                     /gene="rpsJ"
                     /locus_tag="VYO72_001506"
     CDS             complement(16394..16702)
                     /gene="rpsJ"
                     /locus_tag="VYO72_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1707854.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(16968..>17441)
                     /locus_tag="VYO72_001507"
     CDS             complement(16968..>17441)
                     /locus_tag="VYO72_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1707855.1"
                     /translation="NLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDIL
                     ALQAGMDVLTIEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELK
                     RRLARDTTVRNRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
BASE COUNT         4842 a         3845 c         3281 g         5473 t
ORIGIN      
        1 taaatagaac ttaaaatttc tcctattttc ttaattttta aaactatgaa ttggtgctgg
       61 gatttgtcca ccgcgagaga tgaagtcgac agacgaagcc ccattaacct tcataacagg
      121 tgcagttcct aatagaccac caaactcaat catatcgcct tctcttcctt tgggaatgat
      181 acgaacagct gttgttttca tgttgataac accgattgct gcttcatccg caatcatagc
      241 cgcaatggtt tcagcaggcg tatcttctgg gatggcaatc atatccaatc caacagaaca
      301 gatagccgtc atagcttcta gtttttctaa attaagagag ccattttgca ctgcagcaat
      361 cattccttca tcctcagaaa cagggataaa ggcaccagat aaaccaccga cttggttgca
      421 ggccatcact ccaccctttt taacttggtc gttcaagagg gccaaggcag ccgtcgttcc
      481 atgcgtgcca actgtttcta gccccatttc ctcaaggaca cgtgccacag agtctccaac
      541 cgcaggggtt ggtgccaaac tcaagtccac aataccaaac tccacaccca gtctctcact
      601 ggccatttga ccaaccaatt gaccgatacg agtgatttta aaggcagttt tcttaactgt
      661 ttcggctact acatcaaagc tctgtccacg aactttttcc aaagcacgtt tcacaacacc
      721 aggaccagaa actccgacat tgatgataac atctgcttcc ccaacaccat gaaaggcacc
      781 cgccataaat ggattgtcct caacagcatt agcgaataca accaacttgg ccactcccat
      841 atctgaaaga tttgctgttt ccttgataat tcgtcccata tctgccacag ccgtcatatt
      901 aataccagac ttggttgagc cgatattgac tgacgagcag accttatccg tctcagccaa
      961 agcgcgagga atggaattga tgagaatctc atctcccttt tgataacctt tttgtactaa
     1021 ggcagaaaaa ccaccaataa agtccacacc aatctctttc gcagccttat caagcgcttt
     1081 tgccagaacc acgtagtccg tcgcatctgt cgctgcccca atcagagaaa taggtgtcac
     1141 cgatacacgc ttattaacga taggaattcc caactcagcc gcaatttcat caccaacagc
     1201 tactaaatta gccgcctttg tcgtaatttt ttgatagatt ttctccgcag cacgattgat
     1261 atttggatcg atacagtcca aaagagaaat ccccatggta atggttctaa tatcgaagtt
     1321 ttgctcctca atcatggcga tggtttcagt aacttgtcta atatccatga tgacctccta
     1381 gatattatac atagcttcga aaatcgctgc actctgaata ttgattttta cattcaaagt
     1441 ttgcccaaaa gcttcaaatt cattacgaag ataggtaaaa tcttgctttt catcactaga
     1501 tacaacagcc atcatcgtaa aatattcatc caatacagtt tgagagatat cgtcaatatt
     1561 caatcctaat tctgcaattt taccagaaac acctgcaaca attccagatt tatctttacc
     1621 aacaacagtt ataatcgctt tcataagtaa actccaattc ttcttaaaat aagaaacctt
     1681 aacattaaac aggattcttt tcaaatagta tagcataatt ctaacgaaaa tactcaaaaa
     1741 cgcctgctta cgaagttgtt cttaagaaaa aaacaatttc gtaaacaagc gtctactatc
     1801 ccaacttatg atgagtgttc ccgctaggac cgaaatccta gcggtagacc agagctagac
     1861 taagagcaca agactccatc atcataacac tcaacaaaat tgatgatttt atactaattc
     1921 gatgatcgcc attggcgctg catcaccacg acgtggttca gttttaagga tacgagtgta
     1981 tccaccgtta cgttcagcat aacgaggtgc gatttctgag aacaattttt gaagtgctgt
     2041 agtagaagtg tacttatcag ttgcttcatc atagttttca gatgcgattt cattacgtac
     2101 gaaagcagct gcttgacgac gtgcatgcaa atcaccacgt ttacctagag taatcatttt
     2161 ttcaacagtt ttacggattt ctttagcacg agcttcagtt gtcacgattg attcgttgat
     2221 caaaaggtca gttgtcaaat cgcgaagcat tgctttacgt tgtgagctag tgcgtcctag
     2281 tttacggtaa gccatgtatt cctcctttat ttatctttta atccaagacc caaatcaatg
     2341 agtttgagtt tcacttcttc caaactcttg cgtccaagat ttcgtacttt catcatctct
     2401 gcttcagatt tttctgtcaa atcatgcaca gtattgatac cggcacgttt taaacagttg
     2461 tatgaacgca cagacaagtc cagttcctca atcgtacgat ctaaaatacg gtcgtcagat
     2521 tcagtatcag cttctttcat cacttcagtt gacttagcaa tctcagtaag atttgtaaac
     2581 aaatcaagat gttctgtcaa aatacgtgct gaaagcccta aagcatcttc tggaataatt
     2641 gttccatttg tcaagatttc aagggttaat ttgtcgaaac catcattgct acctacacga
     2701 gcaggttcca cttgatagtt gacttttgta actggtgtat aaatagaatc tacagcaagt
     2761 gttccaactg gtgcattatc ctttttattt tcatcagcag gtacatatcc acgaccactg
     2821 ttaacagtca tagtcgcttt tagagaagaa ccttcaccga ttgtaaagag ataatgatct
     2881 ggatttacaa tttcaatatc gctatctgtc aaaatgtcac cagctgttac ttcagcagga
     2941 ccttcaacat ccagttcgat gattttttcg tcttcaacgt acgatttcac tgcaattcct
     3001 ttaatgttca gaatgatttg catcacgtct tcacgaacac ctggaactgt gtcaaactca
     3061 tgtaacacac catcaatgtt gatagatgtc acagctgctc ctggtagaga agctagaagt
     3121 acacgacgaa gagagttacc aagagttgta ccgtagccac gttcaagtgg ttcgattaca
     3181 aacttgccat aatctttatt ttcatcaatt tttgttatat ttggtttttc aaactcgatc
     3241 atttagttac tccctcttaa acgaaaagca gtgtaatgcg atgattatac acggcgacgt
     3301 tttggaggac gagcaccatt gtgtggcact ggagtcacat cacgaattgc tgttacttca
     3361 agaccagcgg cagcaagcgc acgaatagct gactcacgac cagaacctgg accttttaca
     3421 gtaacttcaa ctgatttaag accgtgttct tgtgcagatt tagcagcagc ttcagaagcc
     3481 atttgagcag cgaatggtgt agatttacga gaacctttga aaccaagagc accagctgat
     3541 gaccaagcaa ttgcattacc atgcacatca gtaatcataa caatagtgtt attaaatgta
     3601 gcgtgaatat gagcaatacc agattcgata ttctttttca cacgacgttt acgtgttggt
     3661 ttagccaaga cttttacctc ctatattatt ttttcttacc agcaatcgca acagctttac
     3721 ctttacgagt gcgagcgttg tttttagtat tttgtccacg gacaggaagt ccacgacggt
     3781 gacggatacc acggtatgaa ccgatttcca tcaaacgttt gatgttcaag tttacttcac
     3841 gacgaaggtc accttcaact ttgattgcat ccacttcacg acggatagca tcttcttgat
     3901 ctgatgtaag atcacgtaca cgaacatctt ctgagattcc agcagcagcc aaaattttct
     3961 tagatgttgc aagtccgata ccataaacat aagtcaatga gattactacg cgtttgtcat
     4021 ttggaatatc aactccagca atacgagcca tgttttctcc tttctatctt atccttgacg
     4081 ttgtttgtgt tttggatttg ctgggcaaat taccataaca cgaccattac gacgaataac
     4141 tttacagtat tcgcaaattg gtttgaccga tggtcttact ttcatttctt atccctccaa
     4201 gtttttcgat tatttaaagc ggtaagtgat acgtccacgt gtcaagtcat atggactcat
     4261 ttcgacagta acacgatctc ccgctaaaat acgaatatag tttttacgaa ttttaccaga
     4321 aactgttgct aaaatctgat gtccattttc aagttcaacc gtaaacattg cattcggcat
     4381 tgtatcaact actttgcctt caacttcaat cacatcgtct tttgccacgc aaaagcacct
     4441 ccataaattt cgatttgatg cctctagaca cagagacaac aattataagt cagactattt
     4501 cagtataaca tttgtagcgg atttttgcaa gtgtgaaaaa cgctttattt caaatttgtc
     4561 aatacttttt caatatctga gaagacatca ttgatatctt gattaccttc gatgtcatga
     4621 accaaacctt tggcacggta gtgagcaatg attggttctc cttgagcaat attaacatcc
     4681 aaacgacgtt ttactgtctc aggcttatca tcttcacgtt ggtagtaatc ttcttcttta
     4741 tagtcaactg gtgggttaaa gaccttgtgg aaagtttctc cagttacgcg gtggatgata
     4801 cggccactca aacgttccaa gaggctgtca gggttcactt caatattgat aataccttct
     4861 agttcaatgc caagttcagc caatgttttg tccaaggcat gagcttgttc aattgtacgt
     4921 gggtaaccat ccaataagaa tcctgtttct ttaatatcat cttgtgaaag gcgttctttt
     4981 acgattccat ttgtaacttc gtcaggaacc aattcaccct tgtcaatata tgacttagca
     5041 agaacaccca tttcagtttg atttgccatt gcagcgcgga acatatcacc tgttgagata
     5101 tgtgcaacat ggaattgttc tacgattttt gctgcttgag ttcccttacc tgcaccaggt
     5161 aagcccataa tcaaaagatt catgatttga tctccttatt ttatttttaa atagaagcaa
     5221 aaagtctttt cacccctatt taaaaacaaa atagaagagg ggagatccaa ctcttacaaa
     5281 tgtcagagtt taaacctcca ctccctcagt atttactgat tcagtaaata cttttattct
     5341 gttctgtcca tgaaaccaac atacttacgt ttcaataggt aaccttccaa ttgcttgatt
     5401 ccttcgatac ctgtagagat aatgatcaag agacttgttc caccaaaggc aacaacatca
     5461 gaaagaccaa atacatcttt agctgcaatc ggtaaaatgg aaatcacacc aagaaagagg
     5521 gaaccaacag ttgcaagacg acgaagaagt ttagacatat attcttctgt acctttacca
     5581 ggacgaactc catggatata ggcaccactc ttttgtaggc tctctgctgc tttttcagga
     5641 ttaatctgta caaacgtata gaagaatgta aagagaataa tcaacaaagc atacatggca
     5701 ataccagttg gagaagtagt tgccaacatc tcttgtgcta cccttaccca agcccaatca
     5761 tgacctgtgg cactcaaaaa ctgaagaata gccgcaggcg ctgcagtaat cgaactggca
     5821 aagataacag ggataactcc agcagggttt acctttaacg gaaggtaaga gctagatgga
     5881 gcaccttgtg caaccttagt atattggatt ggaattttgt attctgcttg ttgaacataa
     5941 gttgtaaagt aaataatcaa caatacagta ataatcaaaa tgattacgaa aatgatagat
     6001 gaagtgatac ggctacttgg gacgttcaca aagtagtcca catagatgcc ctgaatcatc
     6061 tctggaattg aggaaacaat cccggcaaag ataatcatgg aaacaccgtt tccgtatccc
     6121 ttatctgtaa tttgctcacc caaccaagtg acaatcatac taccagctgt taagatgata
     6181 ccaatcgtca gaaaaacttg tggagttaaa gcagttttaa tcaattgagc tccagccaag
     6241 gtattaaaac cagctgtaat cccgatagat tgcacaaaag cgagaactag agcaatataa
     6301 cgagtagctt gattcaattt tcttcgacct acttcccctt gtttacccca ctctacaaac
     6361 ttgggtaaaa tatccatttg caagagttgg acaacaatag aagcggtgat atagggacta
     6421 actcctaggg caaaaatcga aaagtttttt agggcattcc ccgacaccaa gctcaacatg
     6481 tttaagaagg ataatccact taaagcattc aagctattgg cattcacacc aggaactgta
     6541 atgctagttc cgatacgaaa gaccaaaacg ataaaaattg taaataaaat ttttgatcga
     6601 acctgcttga ctttaagagc ttctcttaat aatttaaaaa acataggtca cctctcttag
     6661 atgacttcta ctgaaccacc tttagcagtg atagcttctt cagctgattt agagaattta
     6721 gctgctttca cagtcaattt cttagtcaac tcaccgttac caagaatttt aatacctgac
     6781 ttttcagctt taacaattcc tgcttcgata agaacaactg gagttacttc agcaccatct
     6841 tcaaagacgt tcaattggtc aaggttcaca attgcgtatt ctttagcgtt gatgttagtg
     6901 aatccacgtt ttggaagacg acggaacaat ggagtttgtc caccttcaaa accaaggcga
     6961 actccgccac cgctacgagc tttttgacct ttttgaccac gaccagatgt tttaccgtta
     7021 cctgatgaag taccacgacc aacgcggtta cgtactttac gagaaccttc tgcaggtttc
     7081 aattcatgaa gtttcatttt tattttctcc tcttttgtaa aatgctagcg ccgataaggg
     7141 agaaaaggtt gtctccccca tcaactcgcc tatacgatgt catcatagat gactatatct
     7201 agttttaggg gatggtacag tgcacatccc ctaaaacttc attagtttac ttcttcaact
     7261 gttactaagt gagatactgc tgtaatcata ccacggatag cagcgttatc ttctttaata
     7321 acagagctgt tcaatttgcc aagtccaagt gctacaacag ttttacgttg tgatggaatg
     7381 cgtccgattg gagacttagt caaagtaatt ttaatttgag ccattttatc ccctttctta
     7441 tgccaaatca gaaactgaaa taccacgaag ggcagcaatt tcttcagcgc gtttcaattg
     7501 tttcaaacct tcaacagttg cacgaacaat gttgattgga gtgttagaac caagtgattt
     7561 agatgtaata tctgccacac ctgccaattc cacaacggca cgaactgcac caccagcggc
     7621 aactccagaa ccttctacag caggtttcaa caatacttta gctccaccga attctgaaag
     7681 aacttcgtgt gggattgttg ttccaaccat aggaacttcg atcaagtttt tcttagcatc
     7741 atctactgct ttacggattg cttctggaac ttcttgagct ttaccagtac caaatcctac
     7801 gcgaccattg tggtcaccaa caacaacaag agctgcgaaa cgaagacgac gtccaccttt
     7861 aacaactttt gtaacacggt tgacagcaac tacgcgttct tctaattcaa ctgcattgtc
     7921 tttaaatgcc attttctagt gtcctcctat tagaatttca atccgttttc acgagctgca
     7981 tcagccaaag ctttcacacg tccgtgatat agatatccac cgcggtcgaa caccacttct
     8041 gaaatacctt tagcgtttgc acgttctgca acgagtttac cgacagcaac ggcttgttca
     8101 gttttagttc cttttgaaac ttctttatca agagttgaag cacttgcgag cgttacaccc
     8161 gctacgtcat caatcacttg agcgtagatg cctgtattag aacggaatac gttcaaacgt
     8221 gggcgatcag cagttccaga gagttttccg cgaacgcgac ggtggcgttt ttggcggagt
     8281 ttgtttttat ctggttttga aatcacagtt ttcacctctt tagttttaaa tcgtgtgcta
     8341 tgcacaaagt tggaaaatag gttggtggtt gatgatcaac cactcaacat tatttacctg
     8401 ttttaccttc tttacggcga acgaattcac caacgtaacg gataccttta cctttatatg
     8461 gttctggtga acgaaggcta cgtacgtaag cagctgtttg accaactact tcttttgaaa
     8521 ttccgctaac aacgattgtt gttgggtttg gaagttcaaa agtaattcct tctggagctt
     8581 caacttcgtc tggatgagat ttaccaacag ccaaaacaag tttagatcct tgaagctgtg
     8641 cacggtaacc aaccccacgc atttcaagtt ctttcttgaa tccttctgat acaccaacaa
     8701 ccatgttgtt caaaagggca cgagtagttc cgtggatagt tttcatttct tttgaatcgt
     8761 ttggacggtg aagagttatt tcagtacctt ccacacggat ttcaatatct tttgagaact
     8821 cacgagtaag ttctccttta ggtcctttta cagttacaac gttgtcattg ttagcgagtt
     8881 caacaccagc aggcaacacg ataactttat taccaatacg tgacatgttt attttctcct
     8941 gttaaattgt caggccagaa cggccagttt tcacggggtt cagatactta tttagttcaa
     9001 gagctgaact gaacacgctc taagaactgt gcaaaataga taagttggct tgtttgtaaa
     9061 caaacttctc caacttccta attttgcttt gttctttacg agctttgtat cttgatttta
     9121 ccaaacgtaa gcgataacct caccaccaac attcttttgg cgtgcttctt tatcagtaag
     9181 caaaccttca gaagttgaaa ggatggcaat tccaagtccg ttaagaactt ttggaaggtc
     9241 ttcacgtttt ttgtagacac gaagtcctgg tttagaaaca cgtttcaagt tagtgataac
     9301 tttctcacca tttggtccgt atttaagaaa tacacggatg acgccttgtt tgtcatcttc
     9361 aatgatttca acgtttttta caaaaccttc gcgtttaagg atttcagcaa tccctttttt
     9421 gatgtttgat gcaggtactt caagtacttc gtgtttagct tggttagcat tacgaatacg
     9481 agttaggaag tctgcgattg ggtcagtcat aaccattttg tttttctcct cttactagta
     9541 gtttgcaagt tgcacttgct agttaataca tgatacaaag agcgtaacag cacgagcaaa
     9601 aatagacaat ttaatgcaga agcaatgctc caaagcaaat tagtcttttt tgccaaagct
     9661 gtagctcgtg ttcaaattgg caagcccaat tgaacccggg ctaaactctg tgtgaaaaag
     9721 ataaactttc ctagaaactt tagtttcttc gtcaagtttc ctatttttac ttggagtttt
     9781 gacgctcttg atatcttaaa ttaccaagat gcttttgtta caccaggaat ttgaccttta
     9841 tgcgcaagtt cgcgaaaagc gatacgactc agaccaaatt tgcggtaaac tgaatgtggg
     9901 cgccccgtaa ccctacaacg attatgtaaa cgagtcggtg aggcgttgcg aggtaattta
     9961 gataaacctt cgtagtcccc tgccgccttt aatgcagcac gtttttcagc ataacggtca
    10021 acaatttttt ggcgtttagc ctctctagct accattgatt ttttagccat tagatttacc
    10081 tcctatatta ttttgcaaaa ggcattccaa ggcctgtaag caatgcacgt gactcttcgt
    10141 cagtgttagc agttgttacg ataacgatgt caagaccacg agttttgtca acgtcatcga
    10201 agttgatttc tgggaagatt aattgttctt tcacaccaag tgtgtagttc ccgcgtccat
    10261 caaatgattt tgttgggaca ccgtggaagt cacgtacacg tggaagtgaa actgatacca
    10321 atttatccaa gaattcgtac atacgttcac cacgaagggt aacttttgca ccgatcgcaa
    10381 caccttcacg aagacggaag ccggcgattg attttttagc tttagtgata agtggttttt
    10441 gacctgagat aagtgccaat tcttcagcag ctttttcaag gcttttagcg tttgatacag
    10501 cttcaccaac acccatgttc aaaacaatct tatctacttt aggcacagcc atcactgatg
    10561 agtagttgaa ttgttctgtc aaagcaggaa ctacttcatt aagatatttt tcttttaaac
    10621 gatttgccat tatacttctc ctttccttcg tgattaatca agcacttcgc ctgatttttt
    10681 gttgtagcga acttttttac cgtctacaaa tttgtaacca acacgaccag ctacaccatt
    10741 tttgtccaaa acttgaacat ttgatacgtg gatagctgct tctttctcga tgataccacc
    10801 ttgaggaagc tcgttagttg gacgttggtg tttcttaaca atgttaacac cttcaacgat
    10861 aactttgttt acttttggaa gggcagtaag gacaacagct tctgttccct tatctttacc
    10921 agcgattacg cgaactttgt cgcctttttt tacaaacatt aggtttctcc ttgatttttc
    10981 ttacgcccat aagggcaccc tagcttgaag ctaggggact agtttgttcc taaaaattaa
    11041 agtacttctg gagcaagtga cacgatcttc atgaaaccac cttcacgcaa ttcacgtgca
    11101 actgggccaa agatacgtgt tccgcgagga gttttgtctt cacggatgat aactgctgcg
    11161 ttttcgtcaa atttgatgta tgaaccatca gcacgacgag cacctgattt agtacgaacg
    11221 ataactgctt taacaacgtc acctttttta accgcaccac caggagtagc ttgttttaca
    11281 gatgccacga taacatcacc gatgtttgca aatttacgtc ctgaaccacc aagaactttg
    11341 atagtcaaga tttcgcgagc accgctgttg tctgcgactt tcaaacgagt ttctgtttga
    11401 atcatttcag ttttctcctt tcaggtttga ttagatgatg accgcttctt caacaacttc
    11461 tacaagacgg aaacgttttg tagctgaaag cgggcgagtt tccatgatac gtacgatatc
    11521 gccttctttg gcaacattgt tttcatcatg agctttgtat tttttagagt agttaatacg
    11581 tttaccatag actgggtggt tacgttttgt ttcaactaca actgtgattg tcttgtccat
    11641 tttgtcagat acaacacgtc caacaagaac tttacgatta ttgcgttcca ttgaaatttc
    11701 tccttcccta gtctattatt tcgcttcaga ttgaactgtt ttgatacgag cgatttgttt
    11761 tttaacttct ttcaagcgag ctgtttgttc caattgacca gtagcagctt ggaaacgaag
    11821 ttcaaacaat tcttttttca attcgttttc gcgcttcgcg agttcttctt gagaaagacc
    11881 acgaagttct ttaacaaatt cttttacttc attaagtttc atgccttctc cttattctgc
    11941 ttcacgtttt acgaatttac atttaactgg caatttgtgg ctagcaagtc gaagcgcttc
    12001 acgtgcaatc tcttcagata caccagcgat ttcgaacatc actttaccac gtttaactgg
    12061 tgctacccaa ccttcaggtg cccctttacc agatcccata cgcacaccga tagctttagc
    12121 agtgtatgat ttgtgtggga agattttaat ccaaacttta ccaccacgtt tcatgtaacg
    12181 agtcatggcg atacgagcag cttcgatttg gcggttagtg atccagtggc tagttgtagc
    12241 ttgaagaccg tattcaccga atgctacttc ttttccacct tttgcttcac cgcgcatttt
    12301 tccacggaac tcacgacggt gtttaacacg tttaggtact aacattggtt atttacctcc
    12361 tttagtgttt ttacgagctg gaagaacttc accacggtag atccatactt taacaccaag
    12421 tttaccgtat gtagtatctg cttcttccca agcgtaatcg atatctgcac gaagtgtgtg
    12481 aagcggaaca gttccttcag agtatccttc agcacgggcg atatctgcac cgttcaaacg
    12541 acctgatact tgagttttga ttcctttagc tccagcacgc attgcacgtt ggattgcttg
    12601 tttttgtgca cgacggaaag caacacgttg ctccaattga cgagcaattc cttcacctac
    12661 aaggtgagca tccaaatcag gttgtttgat ttcgatgatg ttgatgtgta cttgttttcc
    12721 agtcaatttg ttaagttttg cacggagtgc atcaacgtta gcaccacctt taccgataac
    12781 catacctggt ttagcagtgt gaagtgaaac gttaactttg tttactgcgc gttcgatttc
    12841 aatagttgaa actgctgcgt cagcaagttc tttttgaacg aatttacgga ttgcaagatc
    12901 ttcatgaagg taatccgcgt attctttttc agcataccat ttggcatccc aatcacggat
    12961 gatgccgaca cgcataccaa ttggatgtac tttttgaccc acgattttac ctccttattt
    13021 ttctgcaaca gctacagtga tgtgagctgt acgtttgttg attggtgaag ctgaaccttt
    13081 cgcacgtgga cggaaacgtt tcatagttgg tccttcgttt gcgaatgctt cagatactac
    13141 caagttagct ttatccaaac caaagttgtt ttcagcgtta gctacagctg agttcaaaac
    13201 tttcaagatg atttcagcag ctttgtttgg agtgaatgtc aagattgcga ttgcatcggc
    13261 tacgctttta ccacggatgt tatcaagaac aagacgtgat ttacgaggtg aaacacgtac
    13321 tgtacgagcc attgctttag ctgaagtaat ttctgccatt tatgttctcc ttattttcta
    13381 cgtgttttct tgtcgtctgc agcgtgacct ttgtaagtac gagttggtgc aaattcacca
    13441 agtttgtggc ctaccatgtc ttcttggatg taaacaggta cgtgtttacg tccgtcataa
    13501 actgcaatag tgtaaccaat gaaacttggg aagatcgttg aacgacgtga ccaagtttta
    13561 ataacttttt tcttttcgtc gttagcttga gcttcaactt ttttcatcaa atgctcatcg
    13621 acgaaaggtc cttttttaag actgcgtccc atttttatat tttctccttt aaatgttgta
    13681 ccacagcggc ttgcactcct atggagcgct accgagctgg cggatttact agttgcttaa
    13741 gcgactagtt taatattatt tctcgttgcg acgacgaacg ataagtttgt cagatttcgc
    13801 tttcttgtta cgagttttaa gaccaagagc aggtttgccc catggagtag atggtgcttt
    13861 acgaccaact ggtgctttac cttcaccacc accgtgtggg tgatcgttag ggttcattac
    13921 agaaccacga actgttgggc ggataccttt ccaacggcta cgtcctgctt taccaaggtt
    13981 tacaagtcca tgttgttcgt ttccgacaac accaactgta gcacggcaag ttccaagaat
    14041 catacgaact tcacctgatt gaagacgaac aagaacatat ttaccttcag aacccaatac
    14101 ttgagcagat gcaccagcag cacgtaccaa ttcaccacca cgacctggtt tcaactcgat
    14161 gttgtgaatc aaagtaccaa ctgggatgtt agcaagtgga agagcgtttc cgactttgat
    14221 atctgcttct ggacctgaaa cgatacgttg acctacttca agaccttttg gagcgatgat
    14281 gtatgctttc acaccgtcag tgtagtgtac aagagcgatg tttgcagaac ggtttggatc
    14341 gtactcgatt gttttaacaa ctgcttcaac gttgtcttta ttacgtttga agtcaaccaa
    14401 acggtagaaa cgtttgtgtc caccaccttg gtgacgaact gtgatacgac cgttgttgtt
    14461 acgaccagcc ttgctcttca atgcaacaag caatgatttt tcaggagtgc ttgttgtgat
    14521 ttcagcgaaa tccaaagaag tcatattacg gcgaccgttt gttgttggtt tataaacacg
    14581 aattcccacg atatttcctc cttagattat tcagcttcag cagcaaacaa ctcgattgct
    14641 ttagaatcag ctgtaagtgt gatgatagct tttttagttt tgttagtaaa accagtgtaa
    14701 cgtccaacac gtttagcttt tggttttacg ttgattgtgt taacattggc aactttaaca
    14761 ccttcgaaag cagcttcaac agcttgcttg atcaaaagtt tgtgtgcacg agtgtcaact
    14821 tcaaatacat atttccctgc ttcaagttga gccattgagc tttcagtgat gacaggtttt
    14881 ttgataacat catacaaatt cattatgcaa gaacctcctc gattttagag atagctgctt
    14941 gtgtgacaag aagtttgtcg ctatttgcga tgtcaagaac acttgcagtt gtagcagttg
    15001 caactttcac gtttggaagg ttacgagctg aaagagctgc gaattcattt ccttcttcaa
    15061 ggataacaag aactttagaa tcgatgctca atgctgcaag aacttttgca aattcagcag
    15121 tttttggagc tgtaaatgaa agagcgtcta cagctacgaa tttgttttca gcaacttttt
    15181 cagagtaaac taatttaaga gctaggcgac gaactttttg tggaagtttg tagccgtatg
    15241 aacgtggagt tggtccgaag acaacaccac caccacgcca ttgtggtgag cggatagaac
    15301 cttgacgagc acgtccagtt cctttttgac gccatggttt gcgtccacca cctgatactg
    15361 cagagcggtt tttaacagcg tgtgttcctt gacgaaggct tgcgcgttgg ctgatgatta
    15421 catcaaacac aactgattca tttggttcga taccaaatac tgcatcgtta agaacaactt
    15481 ggccagcttc tttaccagtt tggtcaaata atgttacgtt tgccattgtg actgatttcc
    15541 cctttcttta ttatttacca gctttaactg ctgatttgat agtgataaga gatttcttag
    15601 cacctggtac gttacctttg ataaggataa cgttcttttc tggaacaact tgtacaactt
    15661 caaggttttg aattgttacg cggtcgccac ccatacgtcc tgcaaggttt ttacctttga
    15721 atacgcggtt aggtgcaaca ggccccatag aacctggacg acggtggtaa cgagaaccgt
    15781 gagccattgg tccacgtgat tgtccgtggc gtttgataac accttggaaa cctttacctt
    15841 tagaagtacc agttacatca acaacatctc cagctgcgaa tgtttcaact gtgatttcag
    15901 cgccaacttc caagccttca acgtttttga attcacgaat gaagcgctta ggagccgtgt
    15961 tagctttcgc tacatgtcct ttagcaggtt tgttgctcaa tacttcgcgt ttgtcatcga
    16021 aaccaacttg gatagcgttg tatccgtctg tttcaacagt tttaacttga agaacaacgt
    16081 ttggagttgc ttcaataact gttacaggga tcaattcgcc agcttcagtg aagatttgag
    16141 tcattcccac ttttttccct aagattcctt ttgtcatgag aaaatagttc cttttctata
    16201 ttttttattc aaaaagtttt taacgagcgt tttttatgct caagtctaag atacaaaggg
    16261 cgtcaaactc aaagtgaaaa taggaaacta acgcagtgtc tagcggacaa taggaagttt
    16321 atctttttca caccgagttt agcccgtgtt caattagatt gaaacaccag cctctgctct
    16381 tttatatttt agattaaagt ttgatttcta cgtttacacc acttggaaga tccaatttca
    16441 tcaaggcatc aactgttttt tgagttgggt taacgatatc gatcaaacgt ttgtgtgtac
    16501 gcatttcaaa ttgttcgcga gagtctttgt atttgtgagt cgcacgaatg attgtgtaga
    16561 ggctacgttc agttggaagt gggattggac ccgcaacttg tgcacctgta cgagtagctg
    16621 attctacgat ttttgcagcc gctgtgtcaa gcgtacggtg ttcgtaagct ttcaaacgga
    16681 tacggatttt tttgtttgcc atctttttct ccttttcgtc tatttaagat aataggctag
    16741 ctccacaaga aaaccgacgc ggtgttgcgt ggcaatgcaa ccgagcgtgt cgcaacctct
    16801 tgcatcaaaa ctaaggctgt aatttacagc accataatag aataacacaa atcccctgcg
    16861 attgcaaggg atttgttagg ttttttcgtt tttttgggat gaaactgttt tcctactttt
    16921 tctttctaaa attagggatt ttcttctata tttcttctat acataagtta agtcctcttg
    16981 acatcaaatt tatcttctga ttggtccact aagatatccg ccttagactc agtttcttta
    17041 tagtatcgca gatactgctc ccgtctcatc tgatggctag ccaatataaa ggatgcatag
    17101 cgatttctca cagtcgtatc tctagcaagg cgtcgcttta attcggtctc ctcatccgtg
    17161 tagaaacaga tggttttttc aaagagttcc ttgggtagaa aaccaacaga catcccttcg
    17221 acaatcaaaa ttggtttggc tccagacaag acctcactag ccttccaagg ttcttcaatt
    17281 gtcaagacat ccatacccgc ctgcaaggca aggatatctc tctgcaaact ctccagttca
    17341 tgcgccactg gcagactggc tgtcaccttt tgattcggcg cgtccttggg tactaccaaa
    17401 tagcgtccgg aggtgatata gggatctgtt tctagcaaat t
//
LOCUS       DAVLZG010000046        17225 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLZG010000046 DAVLZG010000000
VERSION     DAVLZG010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17225
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.046"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            332..679
                     /gene="ssrA"
                     /locus_tag="VYO72_001508"
     tmRNA           332..679
                     /gene="ssrA"
                     /locus_tag="VYO72_001508"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(862..949)
                     /locus_tag="VYO72_001509"
     tRNA            complement(862..949)
                     /locus_tag="VYO72_001509"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(913..915),aa:Ser,seq:gga)
     gene            1111..1851
                     /locus_tag="VYO72_001510"
     CDS             1111..1851
                     /locus_tag="VYO72_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1707856.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPAVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1848..2759
                     /gene="pfkB"
                     /locus_tag="VYO72_001511"
     CDS             1848..2759
                     /gene="pfkB"
                     /locus_tag="VYO72_001511"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1707857.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            2756..4708
                     /locus_tag="VYO72_001512"
     CDS             2756..4708
                     /locus_tag="VYO72_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1707858.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YVAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4872..7097
                     /locus_tag="VYO72_001513"
     CDS             4872..7097
                     /locus_tag="VYO72_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1707859.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGSSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(7142..7570)
                     /locus_tag="VYO72_001514"
     CDS             complement(7142..7570)
                     /locus_tag="VYO72_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707860.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            7708..8850
                     /locus_tag="VYO72_001515"
     CDS             7708..8850
                     /locus_tag="VYO72_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1707861.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDGVQALTKIPTEKYLTERVDFATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            8859..10073
                     /gene="thiI"
                     /locus_tag="VYO72_001516"
     CDS             8859..10073
                     /gene="thiI"
                     /locus_tag="VYO72_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1707862.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            10208..11013
                     /locus_tag="VYO72_001517"
                     /pseudo
     CDS             10208..11013
                     /locus_tag="VYO72_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            11035..11774
                     /locus_tag="VYO72_001518"
                     /pseudo
     CDS             11035..11774
                     /locus_tag="VYO72_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            11787..12953
                     /locus_tag="VYO72_001519"
     CDS             11787..12953
                     /locus_tag="VYO72_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1707863.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(13444..15114)
                     /locus_tag="VYO72_001520"
     CDS             complement(13444..15114)
                     /locus_tag="VYO72_001520"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1707864.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            15344..16033
                     /gene="coaB"
                     /locus_tag="VYO72_001521"
     CDS             15344..16033
                     /gene="coaB"
                     /locus_tag="VYO72_001521"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1707865.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            16045..16596
                     /gene="coaC"
                     /locus_tag="VYO72_001522"
     CDS             16045..16596
                     /gene="coaC"
                     /locus_tag="VYO72_001522"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1707866.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            16580..17143
                     /locus_tag="VYO72_001523"
     CDS             16580..17143
                     /locus_tag="VYO72_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1707867.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
BASE COUNT         5037 a         3411 c         3717 g         5060 t
ORIGIN      
        1 gtgcaataag tgaaaagtag tccgaataat ataaggattg attttatagt ttttaaactc
       61 aaatgaatta aaataaagag agtacgaaaa ttctcatctg aaagtatttt agaataattt
      121 tcttcgtgaa tttcttcaaa acagatagct tcatcttagg tatgtgttaa ttggatttcg
      181 taagctctat ttacaatcgt aaagttatgc actgagaaag ttgtagttag tcttccagtt
      241 tgctaaattt ctcgaatagt atctttttta ggtatgtgat ttctttttgc atttttgagt
      301 tagataaggt ataatggttt tattgtcttt tggggtcgtt acggattcga caggcattat
      361 gaggcatatt ttgcgactcg tgtggcgacg taaacgctca gttaaatata actgcaaaaa
      421 ataacacttc ttacgctcta gctgcctaaa aaccagcagg cgtgacccga tttggattgc
      481 tcgtgttcaa tgacaggtct tattattagc gagatacgat taagccttgt ctagcggctt
      541 gataagagat tgatagactc gcagtttcta gacttgagtt atgtgtcgag gggctgttaa
      601 aataatacat aacctatggt tgtagacaaa tatgttggca ggtgtttgga cgtgggttcg
      661 actcccaccg gctccattat tcctttgcat tcttttgcat tccttggtaa aacgttgtta
      721 aatcaacgtt ttttattttt atctttggta ttcctttgca ttcttttgct aaaaagggag
      781 tcacaaacag accctatttt aaaaaaagga tagaaaaaag gatacaacat ttgtcgcatc
      841 ctaaaaataa tcttttttcc acggaagaca tgggattcga acccacgcac gctattacac
      901 gcctaccgcg tttccaacac ggcctcttaa gcctcttgag taatcttcca atacttactc
      961 aaatagtcta ccataaaggc tcttatcttg caataaaaat tctagaaata tgaaaaatga
     1021 tagattttga aagaaaatga taaaaaatgc ttgacttcga aagaaagtat gatagaatga
     1081 atagtgtaaa cgataacagg aggtgattca gtgttaaaaa cagaacgtaa acaactaatt
     1141 ttagaggagt taaatcaaca tcatgtagtt tctctagaaa aattagttag tttgctagaa
     1201 acgtcagaat caacggttcg aagagacttg gatgagttgg aagcggaaaa caagcttcgt
     1261 cgtgtgcatg gtggagcaga actcccccac tccttacagg aagaagaaac cattcaagaa
     1321 aaatctgtca aaaaccttca agaaaagaag ttgctggctc agaaagcagc ctctctcatt
     1381 aaagaaaaag atgtcatctt tatcgatgct ggaacaacaa ctgctttttt gattcatgaa
     1441 ttggtcaata agaatgttac agttgtgacc aactccattc accatgccgc tcagttggtt
     1501 gaaaagcaga ttccagctgt catggttgga ggaaacgtca agacggcgac agatgctagt
     1561 atcgggggcg ttgctcttaa ccagattaac caattgcact ttgaccgtgc ctttatcgga
     1621 atgaatggtg ttgacgatgg ctattatacg actcctgata tggaggaggg agctgtgaaa
     1681 agagctattt tggagaatgc caagcagacc tacgtcttgg tggattcgtc aaaaattgga
     1741 caaacttgct ttgccaaggt agcaccactc aaacgcgcta tcgttatcac tagtcaaggg
     1801 catgagctct tgcaggttat taaggagaaa acggaggtaa tagaagtatg atttatacag
     1861 tcacactcaa tccatccatt gactatatcg ttcgtttgga ccaagtcaaa gttggtagtg
     1921 taaatcgtat ggacagtgat gataagtttg ctggtgggaa aggaatcaat gtcagccgtg
     1981 tcttgaaacg tttgaatata ccaaatacag cgacgggatt tatcggtggc tttactggta
     2041 aatttatcac agatacttta gcagaggaag aaatcgagac acgttttgtc caggtggcag
     2101 aagatactcg tatcaatgtt aaaatcaaag cagaccaaga aacagaaatc aacggaacgg
     2161 gtccaactgt tgaatcggtt cagctagaag aattgaaagc tattttatct agtctgacag
     2221 cagaagatac agttgtcttt gcaggttcaa gtgctaaaaa tctaggcaat gttatctata
     2281 aggatttgat ttccttgacg cgccagactg gtgcgcaagt ggtctgtgac tttgaaggac
     2341 agaccttaat tgatagtttg gactaccagc ctcttcttgt aaaaccaaac aatcatgaac
     2401 ttggagcgat ttttggggtt aaactcgaaa gtttagatga aattgagaaa tacgctcgtg
     2461 agttactggc taagggtgct caaaatgtta ttatctctat ggctggggac ggtgctcttc
     2521 ttgtcacatc tgagggagct tactttgcta aaccaatcaa aggaacagtc aaaaattcag
     2581 ttggggctgg tgattctatg gttgctggat tcacaggtga atttgtcaaa tcaaaagacg
     2641 cagtagaagc cttcaaatgg ggagtggctt gcggaacggc aactaccttc tcagatgact
     2701 tggcaacggc agaacttatt aaagaaacat atggaaaagt tgaggtagaa aaacgatgaa
     2761 aattcaagac ctattgagaa aagatgtcat gttgctagat ttgcaggcaa ctgaaaaaac
     2821 agctgtcatc gacgagatga ttaaaaattt gacagaccac ggttatgtaa cagattttga
     2881 aacatttaaa gaaggaattt tggcgcgtga agctttgact tctactggtt tgggtgatgg
     2941 aatcgcaatg cctcacagca aaaacgctgc tgtcaaagaa gcgacagttc tatttgctaa
     3001 gtcaaataag ggtgttgact acgagagctt ggatggacaa gcaactgacc tcttcttcat
     3061 gattgcagct ccagaaggtg ccaatgatac tcacttggca gccttggcag aattgtctca
     3121 atacttgatg aaagacggtt ttgcagacaa acttcgtcaa gcaacatctg cagaccaagt
     3181 tatcgaactt tttgaccaag cttcagaaaa aactgaggaa cttgttcaag cacctgctaa
     3241 tgactctggt gactttatcg tagctgttac agcttgtaca acaggtattg cccacactta
     3301 catggcccaa gaagcccttc aaaaagtagc tgctgaaatg ggggttggta tcaaggtcga
     3361 aaccaacggt gctagcggtg ttggaaatca actaactgca gaagatatcc gtaaggctaa
     3421 agctattatc attgcagcag acaaggccgt tgaaatggat cgatttgatg gaaaaccatt
     3481 gatcaatcgt ccagttgctg acggtatccg taagacagaa gagctaatta acttggctct
     3541 ttcaggagat actgaagtct accgtgccgc taatggtgca aaagctgcaa cagcctctaa
     3601 cgaaaaacaa agccttggtg gtgccttcta caaacacttg atgagtggtg tatctcaaat
     3661 gttaccattc gttatcggtg gtggtatcat gattgccctt gccttcttga ttgacggtgc
     3721 tttgagtgtt ccaaatgaaa accttggcaa tcttggttct taccatgagt tagcttctat
     3781 gttcatgaaa attggtggag ctgcctttgg tttgatgctt ccagtctttg cgggttatgt
     3841 tgcctactct attgctgaaa aaccaggttt ggtagcaggt ttcgtggctg gtgctattgc
     3901 caaagaaggt tttgcctttg gtaaaattcc ttatgtcgca ggtggtgaag caacttcaac
     3961 tcttgcaggt gtctcatctg gtttcctagg tgcccttgtt ggtggattta tcgcaggtgc
     4021 cttggttctt gccatcaaga aatacgttaa agttcctcgt tcactcgaag gtgctaaatc
     4081 aatccttcta ttgccacttc ttggaacaat cttgacagga tttgttatgc tagctgtgaa
     4141 tatcccaatg gctgcaatca acactgctat gaatgacttc ctaggtggtc ttggaggagg
     4201 ttcagctgtc cttcttggta tcgtccttgg tggaatgatg gctgttgaca tgggtggacc
     4261 agttaataaa gcagcttatg tctttggtac aggtacgctt gcagcaactg tttcttcagg
     4321 tggttctgta gccatggcag cagttatggc tggaggaatg gtgccaccac ttgcaatctt
     4381 tgtcgcaact cttcttttca aagataaatt tactaaggaa gaacgtaact ctggtttgac
     4441 aaacatcatc atgggcttgt catttatcac tgagggagcg attccatttg gtgccgctga
     4501 cccagctcgt gcgattccaa gcttcatcct tggttcagca gtagcaggtg gactcgttgg
     4561 tcttactggt atcaaactca tggcgccaca cggaggaatc ttcgttatcg cccttacttc
     4621 aaatgctctc ctttacctcg tttctgtctt ggtaggagca atcgtaagtg gtgtggttta
     4681 tggttaccta cgcaaaccac aagcataaaa aatagaaaaa tgaaaagatt ggaccgtttg
     4741 gtgcagtctt tttctcttcc cgaaatgcct gtgaaatatg gtataataga agaatggcaa
     4801 acaagaatac aagtacaaca agacggagac cgtctaaagc agaactggaa agaaaagaag
     4861 cgattcaacg aatgttgatt tcgttaggaa ttgcgatttt attgattttc gcagccttca
     4921 aattaggggc tgcaggtata accctttata atttaattcg cttgctagtg ggtagcctag
     4981 cttatctggc gatattcggc ctattaatct atctcttctt tttcaagtgg atacgaaaac
     5041 aggaaggact cttatctggt tttttcacca tatttgctgg cttactcttg atttttgagg
     5101 cctacttggt ttggaaatat ggtttggaca agtccgttct aaaagggacc atggctcagg
     5161 ttgtgacaga tctgactggt tttcgaacga ctagctttgc tggagggggc ttgatcgggg
     5221 tcgctcttta tattccaaca gcctttctct tttcaaatat cggaacttac tttattggtt
     5281 ctatcttgat tttagtgggt tctctcctag tcagcccttg gtctgtttac gatattgctg
     5341 aatttttcag tagaggcttt gccaaatggt gggaagggca cgagcgtcga aaagaggaac
     5401 gctttgtcaa acaagaagaa aaagctcgcc aaaaggctga gaaagaggct agattagaac
     5461 aagaagagac tgaaaaagcc ttactcgatt tgcctcctgt tgatatggaa acgggtgaaa
     5521 ttctgacaga ggaagctgtt caaaatcttc cacctattcc agaagaaaag tgggtggaac
     5581 cagaaatcat cctgcctcaa gctgaactta aattccctga acaggaagat gactcagatg
     5641 acgaagatgt tcaggtcgat ttttcagcca aagaagccct tgaatacaaa cttccaagct
     5701 tacaactctt tgcaccagat aaaccaaaag atcagtctaa agagaagaaa attgtcagag
     5761 aaaatatcaa aatcttagaa gcaacctttg ctagctttgg tattaaggta acagttgaac
     5821 gggccgaaat tgggtcatca gtgaccaagt atgaagtcaa gccggctgtt ggtgtaaggg
     5881 tcaaccgcat ttccaatcta tcagatgacc tcgctctagc cttggctgcc aaagatgtcc
     5941 ggattgaagc accaatccct gggaaatccc taatcggaat tgaagtgccc aactccgata
     6001 ttgccactgt atctttccga gaactatggg aacaatcgca aacgaaagca gaaaatttct
     6061 tggaaattcc tttagggaag gctgttaatg gaaccgcaag agcttttgac ctttctaaaa
     6121 tgccccactt gctagttgca ggttcaacgg gttcagggaa gtcagtagca gttaacggca
     6181 ttattgctag cattctcatg aaggcgagac cagatcaagt taaatttatg atggtcgatc
     6241 ccaagatggt tgagttatct gtttacaatg atattcccca cctcttgatt ccagtcgtga
     6301 ccaatccacg taaagccagc aaggctctgc aaaaggttgt ggatgaaatg gaaaaccgtt
     6361 atgaactctt tgccaaggtg ggagttcgga atattgcagg ttttaatgcc aaggtagaag
     6421 agttcaattc ccagtctgag tacaagcaaa ttccgctacc attcattgtc gtgattgtgg
     6481 atgagttggc tgacctcatg atggtggcca gcaaggaagt ggaagatgct atcatccgtc
     6541 ttgggcagaa ggcgcgtgct gcaggtatcc acatgattct tgcaactcag cgtccatctg
     6601 ttgatgtcat ctctggtttg attaaggcca atgttccatc tcgtgtagca tttgcggttt
     6661 catcaggaac agactcccgt acgattttgg atgaaaatgg agcagaaaaa cttcttggtc
     6721 gaggagacat gctctttaaa ccgattgatg aaaatcatcc agttcgtctc caaggctcct
     6781 ttatctcgga tgacgatgtt gagcgcattg tgaacttcat caaggctcag gcagatgcag
     6841 actacgatga gagttttgat ccaggtgagg tttctgaaaa tgaaggagaa ttttcggatg
     6901 gagatgctgg tggtgatccg ctttttgaag aagctaagtc tttggttatc gaaacacaga
     6961 aagccagtgc gtctatgatt cagcgtcgtt tatcagttgg atttaaccgt gcgacccgtc
     7021 tcatggaaga actggagata gcaggtgtca tcggtccagc tgaaggtacc aaacctcgaa
     7081 aagtgttaca acaataaaaa aatagcttct ttccgagttt ggagggaagc tattttagtg
     7141 gctattgatt gcttttattt tctgaagttg gcgcattgga ctgtttttcg ttttcagtag
     7201 caggtttact tgaagcagga gtagaagagt cctgagttgc tgttttctga tcttcttttt
     7261 tctcttcctt gacgctagat tttggtgttt cctcttgctg tgttttttct tgactagtgt
     7321 tagtctcttt agttggactg gtgttttcct taggggattc cttttggatt tctttgacaa
     7381 tggttgtcgt ctggcttgtc gtaggttctt ttttaatatt tttgttatta tccaaggcgt
     7441 tcataatcgt gatacttgcg gtaatcaagc caaggatact agcgattgta gcaacggttt
     7501 tttgaaagac tgtaaagcct tttttgatgt gttctgtttt tggttttgaa gttctacgat
     7561 agttagacat acattctctc ctttgattat gatttattat actctgtttc tttaaaaaaa
     7621 tcttaaaaaa agagaaattg ccctttcttg tcgcaagctc cgtttcatga tacaatagag
     7681 gaagtgattt tagaaagcgt gagaaacatg atttactttg ataattcagc gacgaccaag
     7741 ccttatcctg aagcccttga aacctatatg caggtcgctt caaaaatttt aggaaaccca
     7801 tctagtctcc atagtttggg agaccaagca acacgaatct tagatgcttc tcgccaacag
     7861 attgcagatt taatcggtaa gaaaagcgat gaaatcttct ttacctctgg tggaacagaa
     7921 ggggataact gggttatcaa gggtgtggcc tttgaaaaag ctcagtttgg caagcacatc
     7981 attgtttcag ccattgaaca tccagcagtc aaagagtcag ccctctggtt gaaaagtcaa
     8041 ggatttgaag tggattttgc tccagttgat aagaaaggct tggtcgatgt tgaggcgtta
     8101 gcaggtttga tacggcctga tacaatcctc gtttctatca tggctgtgaa caatgaaatc
     8161 ggctctatcc aacctattga ggctatttca gaattcttgg cagacaagcc gactatttcc
     8221 ttccacgttg atggggttca ggcgcttacc aagattccga ctgaaaagta tctgacagaa
     8281 cgagtggatt ttgcgacttt ctctagtcac aagttccacg gggttcgagg tgttggcttt
     8341 gtctatatca aatctggcaa gaagattaca cctcttctta caggtggtgg ccaggagcga
     8401 gattatcgtt cgacaactga aaatgtggca gggattgcag cgacagccaa ggccctccgt
     8461 ttgtctatgg aaaagctaga tatctttagg agcaagactg ggcagatgaa ggcagtgatt
     8521 cgccaagctc ttctgaacta tccggatatt tttgtctttt cagatgagga agactttgca
     8581 cctcatattc tgacttttgg aatcaaaggt gttcgaggtg aagtcatcgt tcacgccttt
     8641 gaagactatg atattttcat ctcaacaacc tcagcttgtt catctaaggc aggaaaacca
     8701 gccggtacct tgattgccat gggagtggac aaagataagg ccaagtcagc tgtgcgtctt
     8761 agcctagact tggaaaatga tatgagtcag gtcgagcagt ttttgaccaa gttaaaattg
     8821 atttacaatc aaactagaaa agtaagatag gagcattcat gcagtattca gaaattatga
     8881 ttcgctacgg agagttgtca accaagggta aaaaccgtat gcgtttcatc aataaacttc
     8941 gtaataatat ttcggacgtt ttgtctatct atacccaagt taaggtaaca gcagatcgcg
     9001 accgtgccca cgcttacctc aatggagctg attacacagc agttgcagaa tctctcaaac
     9061 aagtttttgg aattcaaaac ttttctcctg tttataaggt tgaaaaatct gtagaagttt
     9121 tgaagtcttc tgtccaagag attatgcggg acatctacaa ggaaggtatg acctttaaga
     9181 tttctagcaa gcgtagcgac cacaactttg aacttgatag tcgtgaactc aaccaaacac
     9241 ttggaggggc tgtattcgaa gccattccaa atgtgcaagt tcaaatgaaa agtcctgaca
     9301 tcaatcttca ggtggagatt cgtgaagaag cagcctatct ttcttatgaa accattcgtg
     9361 gggctggtgg tttgccagtt ggaacttcag gtaaagggat gctcatgttg tcaggaggga
     9421 ttgactcacc tgtagcaggt tatcttgctc ttaagcgtgg ggtggatatc gaggcagttc
     9481 actttgctag tccaccatat actagtcctg gtgccctcaa gaaagcgcag gacttgaccc
     9541 gtaaattgac caagtttggc ggaaatatcc agtttataga ggtgcctttc acagagattc
     9601 aagaggaaat caaagccaaa gcgccagaag cttatttgat gactctaact cgtcgcttta
     9661 tgatgcggat tactgaccgt attcgtgagg tacgaaatgg tttggttatc atcaatgggg
     9721 aaagtctagg tcaagtagcc agccaaaccc ttgaaagtat gaaggctatc aatgctgtta
     9781 ccaacactcc catcattcgt cctgtggtta ccatggacaa gttggaaatc attgacatcg
     9841 cccaggaaat cgataccttt gacatttcaa tccaaccgtt tgaagactgt tgtaccattt
     9901 ttgcaccaga tcgtccaaaa acaaatccta aaattaagaa tgcggagcag tacgaagcgc
     9961 gtatggatgt tgaaggcttg gttgagcgag cagtggctgg aatcatgatt actgaaatca
    10021 cacctcaagc cgaaaaagat gaagttgatg acttgattga taatctactc taattcagaa
    10081 aatccaaaag aatagcgaaa atcagtaaaa aaagttagtt ttttctctaa aaacaggtaa
    10141 aaaactaact ttttttattt ttatgatata atgatataaa attttgaata tagagagttt
    10201 tctgacaatg aatcaatcct acttttatct aaaaatgaaa gaacacaaac tcaaggttcc
    10261 ttatacaggt aaggagcgcc gtgtacgtat tcttcttcct aaagattatg agaaagatac
    10321 agaccgttcc tatcctgttg tatactttca tgacgggcaa aatgttttta atagcaaaga
    10381 gtctttcatt ggacattcat ggaagattat cccagctatc aaacgaaatc cggatatcag
    10441 tcgcatgatt gtcgttgcta ttgacaatga tggtatgggg cggatgaatg agtatgcggc
    10501 ttggaagttc caagaatctc ctatcccagg gcagcagttt ggtggtaagg gtgtggagta
    10561 tgctgagttt gtcatggagg tggtcaagcc ttttatcgat gagacctatc gtacaaaagc
    10621 agactgccag catacggcta tgattggttc ctcactagga ggcaatatta cccagtttat
    10681 cggtttggaa taccaagacc aaattggttg cttgggcgtt ttttcatctg caaactggct
    10741 ccaccaagaa gcctttaacc gctatatcga gtgccagaaa ctatcgcctg accagcgcat
    10801 cttcatctat gtaggaacag aagaagcaga tgatacagac aagaccttga tggatggcaa
    10861 tatcaaacaa gcctatatcg actcgtcgct ttgctattac catgatttga tagcaggggg
    10921 agtacatctg gataatcttg tgccatccat agtgaaatcc cttggtcaga aaatctacca
    10981 gattgtctga gattttttgc agaaaaatgg taagttaaga aaggaaaaaa cgaaatgcat
    11041 attgaacatc ttagccactg gagtggtcat cctaaccgtg aaatgtacct taaccgttat
    11101 ggacatggtg ggattccagt tgtggtcttt gcttcatcag gtggtagtca caacgaatac
    11161 tatgattttg gcatgattga tgcctgtgct tcctttatcg aggaaggccg tgtccagttc
    11221 tttaccctat ctagtgtgga tagtgagagc tggttggcta cttggaaaaa tgctcatgac
    11281 caagcggaaa tgcaccgtgc ctacgaacgt tatgtgattg aggaggccat tcttttatca
    11341 agcacaagac aggttggttt gatggcatga tgacgacagg ttgctctatg ggagcctatc
    11401 atgcacttaa tttcttcctc cagcatccag atgtctttac caaagtgatt gctctcagtg
    11461 gtgtttacga cgcacgtttc tttgtcggtg attactacaa cgatgatgct atttaccaaa
    11521 actcgccagt agattatatt tggaaccaaa acgacggctg gtttattgac cgttaccgtc
    11581 aggcagagat tgtgctgtgt acggggcttg gagcctggga acaagatggt ttaccatcct
    11641 tttacaagct caaagaagcc tttgaccaga aacaaattcc agcctggttt gctgaatggg
    11701 gacatgatgt cgcccacgac tgggaatggt ggcgtaaaca aatgccttat ttcctcggta
    11761 atctctattt ataaaaggag ttacctatga attaccttgt tatttctccc tactatccac
    11821 aaaactttca acagtttacc atcgaactag ctaataaagg catcacagtc ttgggaattg
    11881 gtcaagagtc ttacgagcaa ttggatgagc ccttgcgcaa tagcttgacc gagtattttc
    11941 gtgttgataa tcttgagaac atagatgaag tcaaacgtgc agttgctttt ctcttttata
    12001 aacatggtcc aattgaccgc atcgagtctc acaatgaata ctggcttgag ctagacgcaa
    12061 cactcagaga acaattcaat gtttttggtg ccaaaccaga ggatctcaaa aagacgaaat
    12121 ataagtctga aatgaagaaa cttttcaaaa aagcaggtgt tcctgtggta cctggagctg
    12181 ttatcaagac ggaagcagat gttgatcaag cagtgaaaga aatcggtctt ccaatgattg
    12241 ccaaacctga taatggagtg ggagcagccg caacctttaa acttgagaca gaagacgata
    12301 tcaatcactt caagcaagaa tgggaccatt caacccttta tttctttgaa aaatttgtca
    12361 cttccagcga aatctgtacc tttgacgggc tcgtggacaa ggatggaaag attgtcttct
    12421 caacaacctt tgactacgcc tatacaccgc ttgacctcat gatttataag atggacaatt
    12481 cttattatgt gctcaaggat atggatccta aactgcgcaa gtatggggaa gcaattgtca
    12541 aagaatttgg tatgaaagaa cggtttttcc atattgagtt cttccgtgag ggggacgatt
    12601 atattaccat cgagtacaat aaccgccctg caggtggttt taccattgat gtttataact
    12661 ttgctcattc cttggacctt tatcgtggct atgcagctat tgtcgcagga gaggagttcc
    12721 cggcgtcaga ctttgaaact cagtattgtt tggctacttc tcgccgtgca aatgctcact
    12781 atgtttattc agaagaggat ttgcttgcca aatatagcca gcagttcaag gttaaaaaag
    12841 tcatgccagc tgccttcgcg gaacttcaag gagattacct gtatatgctg acaactccga
    12901 gtcgacaaga aatggatcag atgattgctg atttcggaca acgtcaagaa taagaactat
    12961 cggattaagg aaattcactc ccttaatcct tttgttttgt ctggtaaaaa ataagagcat
    13021 cctaacaagg tagctatcat aaaacttgtt cgataactat ttgaagcagg attaggtggc
    13081 tagaaattga attttaacat ttcaattgag tcatagtatt gtgttttcgt atccttaaat
    13141 cagctaaaag gatccatgac gacacctata cgatatagtt ttcaggatac caaacaagtc
    13201 tattaatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaaa
    13261 cactgttttg aggttgtgga tagaactgac agagtcagta tcatatacct acggcaaggt
    13321 gaagctgacg tagtttgaag agattttcga agagtataaa tcttattgat gaactgcttg
    13381 cagtctgaga aaaaatgagc ttggatatta tttccaaact cacttaaagt caatttcaat
    13441 ccactagaac aagcctagta cagttccatc gctttcaaca tccatgttga gagctgctgg
    13501 acgttttgga agacctggca tggtcataac atcaccagtt aaggcaacga tgaagcctgc
    13561 acctaatttt ggtaccaatt cacgaatggt aatttcaaag ttttctggtg ctccaagcgc
    13621 atttggattg tctgagaaac tgtattgagt tttagccata cagattggca atttgtccca
    13681 accgttttga acgatttgag caatttgtgt ttgagctttc ttctcaaagt tcactttgct
    13741 accacgatag atttcagtga caattttttc aatcttttct tggacagaaa ggtcattatc
    13801 gtacaaacgt ttatagttag ctggattttc agcaattgtc ttaacaactg tttcggcaag
    13861 tgctactcca ccttctgctc catcagccca gacactagcc aattcaactg gtacatcgat
    13921 tgaggcacag agttctttta aggctgcaat ttcagcttct gtatcagata caaattcgtt
    13981 aatagctaca actgctggaa taccgaactt acggatattt tcaacgtggc gtttcaagtt
    14041 agcaaaacct gcacgaactg cctctacatt ttcttcagtc agagcgtctt tagccacacc
    14101 accattcatc ttaagggcac gaagggttgc gacaataaca actgcatctg gagatgttgg
    14161 caagtttggt gtcttgatat caaggaattt ctcagcacca aggtccgcac caaaaccagc
    14221 ttcagtaaca gtgtaatcag ccaagtgaag ggctgttgtc gtcgccaaaa cagagttaca
    14281 gccatgagcg atattggcaa atggaccacc gtgtacaaag gcaggtgtac cgtaaattgt
    14341 ctgaaccaag tttggcttaa tagcatcctt caaaatcaaa gccaaggcac cctcaacctg
    14401 caaatcacct acagaaacag gcgtacggtc atagcgataa ccaataacga tattcgccaa
    14461 acgacgtttc aagtcctcga tgtccgttgc caagcaaaga attgccatga tttctgaagc
    14521 aactgtaata tcaaaaccat cctcacgtgg aataccgttt agaggaccac caagaccaac
    14581 agtcacatgg cggagcgcac ggtcgttcaa gtccacaacg cgtttccaga ggatacgacg
    14641 ttgatcaatt tccagctcat tcccttggtg caagtggttg tcaatcaagg cagaaagggc
    14701 attgttggca gttgtaatag catgcatatc tccagtaaag tggaggttga tgtcttccat
    14761 tggcagaact tgtgcatacc caccaccagc agcaccaccc ttgatcccca tgactggacc
    14821 aagagacggt tcgcggatag caatcatggt tttcttgcca atcttgttca aggcatccgc
    14881 aagaccaatg gtaagtgtcg actttccttc acctgcaggt gttgggttga tggcagtaac
    14941 caagatcaat ttaccgactg gattgctctc aactgcacga attttatcaa agctgagttt
    15001 agccttgtac tttccgtaca actccaaatc gtcataagaa ataccaagtt tctctacaac
    15061 atcaacaatt ggcttcaact caatactctg tgcgatttca atatctgttt tcattcaaaa
    15121 ttcctctaac ctcttatatg ataattcatt atatcacaaa acaagatttt taacatccta
    15181 aaactctcta aacgttcgta aatatctctg tttttaaggc ttttagagtc ctttcttaaa
    15241 ttttatatgg ttttatagtt tgaaactata gtaaatcttc gtttttacca aaaatttatc
    15301 actttcattt tacttaccgc ttatttttgt gtacaatagt gctatgaaaa ttttagttac
    15361 atcgggcggt accagtgaag ctatcgatag cgtccgctct atcactaacc attctacagg
    15421 tcacttgggg aaaattatca cagagacttt gctttttgca gggcatgaag tttgtttaat
    15481 tacgacaaaa cgagctctga agccagagcc tcatcctaac ctaagtattc gagaaattac
    15541 caataccaag gaccttctaa tagaaatgca agaacgtgtt caggattatc aggtcttgat
    15601 ccactcaatg gctgtttctg actacactcc tgtttatatg acagggcttg aggaagttca
    15661 ggctagctcc aatctaaaag aatttttaag caagcagaat catcaggcca agatttcttc
    15721 aactgatgag gttcaggttt tgttccttaa aaagacaccc aaaatcatat ccctagtcaa
    15781 ggaatggaat cctactattc atctgattgg tttcaaactg ctggttgatg ttaccgaaga
    15841 tcatctggtt gacattgcac gaaaaagtct tatcaagaat caagcagatt taatcatcgc
    15901 gaatgacctg actcaaattt cagcaggtca gcaccgagct atatttgttg agaaaaatca
    15961 gcttcaaaca gtccagacta aagaagaaat tgcagaactc ctccttgaaa aaattcaagc
    16021 ctatcattct tagaaaggaa aactatggca aacattctct tggctgtaac gggttcaatc
    16081 gcctcttata agtcggcaga tttagtcagt tctctaaaaa aacaaggcca tcaagtcact
    16141 gtcttaatga ctcaggctgc tacagagttt atccaacctt tgacactaca ggtactctca
    16201 cagaatcctg tccacttgga tgtcatgaag gaaccctatc ctgatcaggt caatcatatc
    16261 gaacttggaa aaaaagcaga tttatttatc gtggtacctg caactgctaa cactattgca
    16321 aaactagctc acggatttgc ggacaacatg gtaaccagta cagctctagc cctgccaagt
    16381 catattccca aactaatagc tcctgctatg aatacaaaaa tgtatgacca tccagtaact
    16441 cagaataatc tgaaaacatt agaaacctac ggctatcagc tgattgctcc taaggaatcc
    16501 ctactagctt gtggagacca cggacgagga gctttagctg acctcacaat tattttagaa
    16561 agaataaagg aaactctcga tgaaaaaacg ctctaatatt gcacccattg ctatcttttt
    16621 tgctaccatg ctcgtgatac actttctgag ctcacttatc tttaaccttt ttccatttcc
    16681 aatcaaaccg accattgttc atattcctgt cattattgcc agcattattt atggtccacg
    16741 agttggggtt acacttggat ttttgatggg gctacttagc ttgacggtta acacgattac
    16801 gattctaccg acaagctacc tcttctctcc cttcgtacca aacggaaaca tctactcagc
    16861 tatcattgcc atcgtcccac gtattttgat tggtttaact ccttacttag tctataaact
    16921 gatgaaaaac aagactggtc tgattttagc tggagccctt ggttccttga caaatactat
    16981 ctttgtcctt ggaggaatct tcttcctatt tggaaatgtt tataatggaa atatccaact
    17041 tcttctggca accgttatct caacaaattc aattgctgaa ttggtcattt ctgcaattct
    17101 aaccctagcc attgttccac gactacaaac cttgaaaaaa taaaaacaat ctccgctttc
    17161 aaacctgaag gtggagattt tgctctatac agtttctttt taatgaaatc tttactatag
    17221 taaaa
//
LOCUS       DAVLZG010000047        16936 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLZG010000047 DAVLZG010000000
VERSION     DAVLZG010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.047"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(276..1910)
                     /locus_tag="VYO72_001524"
     CDS             complement(276..1910)
                     /locus_tag="VYO72_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707868.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1891..2640)
                     /locus_tag="VYO72_001525"
     CDS             complement(1891..2640)
                     /locus_tag="VYO72_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707869.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            2819..4273
                     /locus_tag="VYO72_001526"
     CDS             2819..4273
                     /locus_tag="VYO72_001526"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1707870.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4363..6981)
                     /gene="alaS"
                     /locus_tag="VYO72_001527"
     CDS             complement(4363..6981)
                     /gene="alaS"
                     /locus_tag="VYO72_001527"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1707871.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(7003..7488)
                     /locus_tag="VYO72_001528"
     CDS             complement(7003..7488)
                     /locus_tag="VYO72_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1707872.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7763..8002)
                     /locus_tag="VYO72_001529"
     CDS             complement(7763..8002)
                     /locus_tag="VYO72_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707873.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8263..9333)
                     /locus_tag="VYO72_001530"
     CDS             complement(8263..9333)
                     /locus_tag="VYO72_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1707874.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9330..10103)
                     /locus_tag="VYO72_001531"
     CDS             complement(9330..10103)
                     /locus_tag="VYO72_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707875.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(10100..10906)
                     /locus_tag="VYO72_001532"
     CDS             complement(10100..10906)
                     /locus_tag="VYO72_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707876.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10887..12044)
                     /locus_tag="VYO72_001533"
     CDS             complement(10887..12044)
                     /locus_tag="VYO72_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707877.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12103..13053)
                     /gene="murB"
                     /locus_tag="VYO72_001534"
     CDS             complement(12103..13053)
                     /gene="murB"
                     /locus_tag="VYO72_001534"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1707878.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(13165..13917)
                     /locus_tag="VYO72_001535"
     CDS             complement(13165..13917)
                     /locus_tag="VYO72_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1707879.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13927..14658)
                     /gene="budA"
                     /locus_tag="VYO72_001536"
     CDS             complement(13927..14658)
                     /gene="budA"
                     /locus_tag="VYO72_001536"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1707880.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14800..16071
                     /locus_tag="VYO72_001537"
     CDS             14800..16071
                     /locus_tag="VYO72_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1707881.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(16091..16906)
                     /locus_tag="VYO72_001538"
     CDS             complement(16091..16906)
                     /locus_tag="VYO72_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1707882.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
BASE COUNT         5113 a         3813 c         3328 g         4682 t
ORIGIN      
        1 atttcaccta tttgcatcat tctatttcga actctaaata tatgttctat caaaaatact
       61 tggatcacac acattatagg aattaacgtt tttgaaattg aaaaatatcc caataaataa
      121 actataaaca acaataatag aactatatta tatttcttat tcaaaacatt cctccctata
      181 tttttgatta ccaatcttaa tcatttacaa ctacattcta acaaactata aaagcgtttg
      241 tcgaattgaa tttatcaagc aagcaaccaa ctatctcatc ttttttctat ttctgccaat
      301 atgcgtgaca ggtaataatg atagccaaaa atagcaagag caagcaagac gataagagct
      361 cctactccca agttgatggc aaggataggg gagagagact gaaccaagaa tatgctccca
      421 attacaaggg ccatcaggat tgcactataa ataaacaata aaactatggc gactatgcca
      481 tttgaacgat tcaccaggtc cgtaatgcta ctccaattgg ttgacagatt tttaacgtcc
      541 ttaaagtaat ggtggcaaga aaggatgaca ctggcaatga tccagactac aagaaggtaa
      601 atcatcgaaa ggatgggcaa gcctagatat agagaaagac cgagcaaagt cagaactggt
      661 aaaaaggact gaacagcaaa gataatccaa aatttcactt tcacataacg agcaaagtca
      721 aagggtaaac tcttcagaaa atcaacattt tccctctcca aggacaaggc aattgaatgc
      781 aggctggtga tattgttatt gacaactgct ataaacactc ctacaaaaaa caagggtaac
      841 cagtatggag gatgaatgtc tggaactatc tgagaatctc ggattttgga aatcagactg
      901 atcatcatga gataaggaag gaaagcactt gtaaaaagca ctgtaatcac accagtcccc
      961 tgtcccaaga gggtgaggtg gtagcgtaaa accatacgga aaaagccctt tttagtagtt
     1021 gaaatcctct ccttgctgcg acgttctttt ttgaccttct cctcactgtt aagcaggatc
     1081 acgtcataaa aacgaggaag gaccttcttt ttggtcagat aaagcaggaa gagagttagt
     1141 cctatccaag cgagcagacc cactaaggct tctgtcgaaa aaggctccac tgctattttg
     1201 taaaagatat gaagaggata aaggagaaat ggaatgtctc taactttgtc aacaatactt
     1261 ccaaaagtcg actgaagaaa gaagataaat attaaaggta tgagaactcc tatcccaatc
     1321 atcacattcg aaaaaataga ctgatacttt ctgaagaccc tagtctgagc caagaaatgt
     1381 actgccacta ccgtcactaa agtaacagag acaaataata aggtcaagga cagtagcatc
     1441 aaaggcaaac ccagccaaag agaaggagct agactaatat agagggctag aaaataagct
     1501 aggattggta caattccagt tagagctggc aagaggacag acagaccttt ggccattata
     1561 atctctgatt ctttaaaggc atagggccta taggaggcca ggtccttact ctcataaaag
     1621 acattgtaaa aggcagtgaa agaagttgaa aaggccagca ccagtaaaat agcaaccatc
     1681 gagctaaaat aaataggcat ttcctcaaaa ggaaaatgaa tggctatatt actaaaacag
     1741 atgagcatca agagactgga aaaaatgtaa gaacttagga ctctagcaga aacatttact
     1801 tttttcccag gattcttagc ctgcttcttt cgtagattag ccagattagc ttcttgagat
     1861 gaatagagga tattgatatc aactaatttt ttaatgacct tgagacgcat ccgcaacctc
     1921 ctcttttcta ccagcaagac taaggtagat actttccaaa aactggtctg ggtggtcttt
     1981 cctcaagttc tctacactac cacaatagat caaatgcccc tttttcaaaa tagcaatccg
     2041 atcacagact tgctcggcta cctcaaggac atgagttgaa aacaagaccg tcttgccttt
     2101 ttgtgcatgt tccttcatca tttgcttcaa atcaaaggcg gcctggggat ccaaaccagt
     2161 caagggttcg tccaaaaccc aaatatcagg agcagacaag agtgccccaa tgacaaagac
     2221 tttctgacgc attccgtgag aaagagtttc aataacctga tagcggtttt cagcaaaatc
     2281 aaaaacgttc aatagcctag ctagactagt ctccaagtca gagctagtca gatcatagga
     2341 tgaagcgatc aattcccaaa attcattggc cgttaagcgt aaaaataagt caggcgagtc
     2401 tgctacgtag ccaatctttc gtttgatcgc caagcgattt tccgataact cctgaccgtc
     2461 taccaaaata cgaccactgc tgggtgaaat gatactgact agggatttta tggtggtcga
     2521 ttttccagcc ccattatgac caatcaagcc cataatctct ccattttcaa tctgcaaatt
     2581 gagattactc aaggcctctt tatcaccata caacttacta acattttgaa attcaatcat
     2641 gggacaactc ctatctttat ctgtattata catcgctata ctagcacttt gatacaaaaa
     2701 aatcaatact ttattttaag tagttaaaat agtttccttc tatcttacgc aaacgtttgc
     2761 gccgagagat actttatgat agaataaaga acaagattga caagtaagag gaaacatcat
     2821 gcaaaatcaa acactcatgc aatactttga atggtatctg ccccacgacg gtcaacactg
     2881 gacgcgtctg gctgaaaatg ctccacacct agctcatctg gggatcagtc acgtctggat
     2941 gccaccagcc ttcaaggcaa ccaacgaaaa agatgtcggc tatggggtct atgacttatt
     3001 tgacttagga gagttcaacc aaaaagggac tgtccgcacc aagtatggtt tcaaagaaga
     3061 ctatcttcaa gccattcaag cccttaaaga acagggaatt caacctatgg ccgatgtagt
     3121 tctcaaccac aaggctgctg ccgataacag ggaagccttt caggttatcg aagttgatcc
     3181 tgtagaccgt acagttgaac ttggagaacc cttcaccatc aatggctgga ctagttttac
     3241 cttcgatggt cgccaagata cctataatgg cttccactgg cattggtacc acttcaccgg
     3301 tacagactac gatgccaaac gcagtaaatc tgggatttat ctgatccaag gggacaacaa
     3361 gggctgggct aacaaggaat tggtcgataa cgaaaacgga aactacgact acctcatgta
     3421 tgccgaccta gactttaaac atcctgaagt catccaaaac atctatgact gggctgattg
     3481 gttcatggaa acgactggtg tagctggttt ccgtttggat gccgttaagc atattgactc
     3541 tttctttatg cgcaacttca tccgcgatat gaaggaaaaa tacggtgacg atttctatgt
     3601 ttttggtgaa ttttggaacc cagacaagga agccaatctg gactatctcg aaaaaacgga
     3661 agaacacttt gaccttgtcg atgttcgtct ccaccagaat ctctttgaag ccagtcaagc
     3721 tggcgcaaac tatgaccttc gtggcatttt cacagatagc ctggttgaac tcaagcctga
     3781 caaggctgtg acttttgtcg acaaccacga tacccaacga ggacaagccc ttgagtctac
     3841 cgttgaagaa tggttcaagc cagcagccta tgccctcatt ttgttacgcc aagacggcct
     3901 tccatgtgtc ttttacggag actactatgg gatttcaggc cagtatgctc aagaagattt
     3961 caaagaaatc cttgaccgcc tcctagccat ccgaaaagac ttggcctatg gagaacaaaa
     4021 tgactacttt gaccatgcta actgtatcgg ttgggtacgt tcaggtgctg aaaatcaatc
     4081 cccaatcgca gtccttatct caaatgacca agaaaacagc aagtcaatgt ttgtcggtca
     4141 agaatggact aatcaaacct ttgtagattt acttggtaac caccaaggtc aagttacaat
     4201 tgatgaggaa ggttatggac aattccctgt ctcagctaga tccgtaagtg tctgggcagt
     4261 caataccatc taatagctca taataaccaa gctaggtcca agcggatttg gcttttttgt
     4321 attcacaaaa agacctaccc aaatggatag atctttactt gattacaatt tacctgctac
     4381 tgcatccaac aattcttgga tcttagcttg gttgcttcct cctgccatgg ccatgtctgg
     4441 tttaccacca ccacgtccat cgatgattgg tgctaattct ttgacaaggt ttcctgcatg
     4501 aaggtctttt gtcttgcttg ctacaaggac attgactttg tcaccgatag cggcaactag
     4561 gacaagaaga tcagagtagt ctttttgttt ccagttatct gcaaaagtac gaagggcacc
     4621 ggcatcggat acagacactt gactagcaat gtaacgatga ccgttgactt ccttaacatc
     4681 tttgaagata tcgcctgcgg ctgcagctgc ggctttttct ttcaactcag cattttcttt
     4741 ttgaagttga cgaagttgtt cttgaagtcc ttctaccttg tgaggtactt ccttgacttg
     4801 aggtgctttc aaggttgctg cgatagcttt aagagcatcc tcttgttcac gataggcttc
     4861 aaaggcttcc ttaccagtca ctgccaagat acggcgagtt cctgaaccga ttccttcttc
     4921 tttgacaatt ttgaagagac caatctcaga agtgttgtca acatgagtac caccacaaag
     4981 ttcaatagag tagtcaccga tagtcacgac acgaacttcc ttgccgtatt tctcaccaaa
     5041 gagggccata gctcccattt ctttagcagt gtcaatatcc gtttcaactg tcttcacttc
     5101 aagtgcttcc caaattttct cgttaacttg ctgttcaatc gcacgaagtt cctcagcagt
     5161 tactgcttgg aagtgggtaa agtcaaagcg aaggaattca acttcgttaa gagatcctgc
     5221 ctgtgttgcg tggtttccaa ggatattgtg aagggcagcg tgaagcaaat gagtcgcagt
     5281 gtggtttttc atgacacggt gacggcgatt gctatcaatt gccaaggtat attcttggtt
     5341 caaggcaagc ggtgcaagga cttcaactgt atgaagggct tgaccatttg gggctttctg
     5401 aacattggtc acagtagcca caatcttacc tgactcatcc aagatttgtc cgtagtcagc
     5461 tacctgtcca cccatttcag cataaaatga cgtttccgca aagataagag aggcagttcc
     5521 ttctgaaaca gctcctactt ctgcattgtc agcaacgata gctaccaatt tagaagacaa
     5581 ttggctagta ttgtagttga agacactttc tacagtgatg ttttgaagag tttcattttg
     5641 catacccatt gagccaccct tgacagctga cgcacgcgcg cgttcttgct gttctttcat
     5701 ggctgcttca aaaccttcac ggtctacagt cataccagct tcttcagcga tttcttcagt
     5761 caattcaact gggaacccat aagtatcata gagtttaaag acatcttgac cagcaatgac
     5821 agattgacct ttttctttca agtctgccac aatgccttgg gcaaagtgtt gacctgagtg
     5881 aagggtacgg gcaaatgatt cttcttcgct cttaacgatt ttctcaataa agtcacgttt
     5941 ctcaagcact tctgggtagt agctttccat gatttttcca acagttggaa ccaatttgta
     6001 aaggaaaggc tcgttgatac ccaatttttg accatgcata gaagcacgac ggagaagacg
     6061 acgaagaaca taaccacgac cttcatttcc tggaagggca ccatcaccga tagcaaatga
     6121 aagagaacga atgtggtctg cgataacctt gaagctcatg ttgtcgccat cttggtcata
     6181 aaccttacca gacaatttct cgacttcacg gataatcggc atgaagaggt ccgtttcaaa
     6241 gttggtctta gccccttgga taacggccac caaacgctcc aaaccagcgc ccgtatcaat
     6301 gttcttatgt ggcaattcct tgtattcgct acgaggaaca gcagggtctg cgttaaattg
     6361 tgacaaaacg atgttccaga tttcaatata acggtcgttt tcaatatctt ctgcaagcag
     6421 gcgaagaccg atattttctg ggtcaaaggc ttccccacgg tcaaagaaga tttctgtatc
     6481 tggtccagaa ggtcccgcac cgatttccca gaagttgtcc tcaattggaa tcaagtgact
     6541 tggatccact cccacttcaa tccagcggtt gtaagaatct ttatcgtctg gatagtaggt
     6601 catgtaaagt ttttcagcag ggaaatcaaa ccattcaggg cttgtcaaaa gctcataagc
     6661 ccaagtgata gcttcgtcac ggaagtaatc cccgatagag aagttcccca gcatttcaaa
     6721 catggtatgg tgacgcgcag tcttccctac gttttcgatg tcgttggtac ggatagcctt
     6781 ttgggcattg gtaatacgtg gattttcagg gataatggtc ccgtcaaagt atttcttaag
     6841 ggttgctacc ccagagttga tccacaaaag agttgggtca tttacaggaa ccaaacttac
     6901 tgatggttct actgagtgac ctttggtcgc ccagaaatca agccacattt ggcgtacttg
     6961 tgcactagat agttgtttca tattgtctcc ttattcactt gtttaatgtg attggctttc
     7021 cagcatttcc acatagtcaa tcgcgacaca gagggaaatg actaggtctg cataagcgtc
     7081 ttcaagaacc gttacggtat aggtagaggt cagatggaag agttccttct taatttccgc
     7141 aatcaactga tcgcgatcat ccagcaattt gaaattcaaa tcccagatat tgccctcgat
     7201 acgaagacct agattatcaa actcatactt atctcgccag aaggtcaact tcttacgaat
     7261 gacaaaactc gagccatccc gaagctgaat ctcaaaacga ggaagcaagg tcaagatttc
     7321 tttactgatc tgactgactt gttcaccagc cgcatcatag atggtaaaag ttttgggaat
     7381 cttaaaaaat gatccctcca cctgataggc aatttctccc ctgtcatcct tgatagcgaa
     7441 gcgttcgcct ccaagacgaa acttttgttt gacaagaaat gttttcatca acacctccaa
     7501 aaatcaaaag acaagctcat atcacgaagg gcgaaaaacc gcggtaccac cttcattcaa
     7561 tgaacttgtc attctcttgt tcttatgcaa ttgtatgatt gagtagcatg acttcctagc
     7621 ttagatggct cgcagcaccg ccatttctct ggactaagac aagtgaaaat caattctcaa
     7681 ctttcttatt ataacgtttt tttaagcttg cgtcaactgg aaatgatctc cgttgaatta
     7741 gaccaattcc ctacatctct gattactttt tcaggatata ttttttctta ctgccatttt
     7801 tctttttatc ccaaattttc atattactaa acacagctac tagaatattt ccaaatataa
     7861 aggtgcctat cacccaatat atggactcag ttgttaggta ttgtcgatcc aagccatcat
     7921 ttaaatggaa tagtatagca gtttggttaa caatcataaa ggttggccag aaactttttt
     7981 tgaaaaaagt agacattttc attatttgtt gccgctttct gtaaggttaa tactcaataa
     8041 aaatcaaaaa gcaaactagg aagctagctt caagctgtac ttgagtacgg caaggcaacg
     8101 ctgacgtggt ttgaagagta taggcttagt atactactag gcaagcaaat aagcaaataa
     8161 acaaataaac aactagaata gaaaaagata gggctctaaa aactgacttc tattccttaa
     8221 aaacgaacca gcttgactga ttcgtcttct tacgtttatc tcctacttcc gatacatttt
     8281 aaactgtagg aagaggtcgc tatatttccc tgtccattta tggtcaaatt tctcataaac
     8341 ttctaggtgt ttcatggttt caacatcggg atagaaggcc ttatcttcct ttgtttcctc
     8401 tgggagcaat tccttcgctg gtaggtttgg tgttgaatag ccgacatact ccgcattttg
     8461 gagagcattt tcaggtttca acataaagtt gataaaggca taggctgagt cttgattttt
     8521 aactgttttg ggaatgacca tattgtcaaa ccaaagattg ctggcctctg tcggtaccac
     8581 ataacgtaga ttttcatttt tttctaacat ttggctggct tcaccagaga aggtcacgcc
     8641 gattgcaaca ttattctgaa tcatgtagcc cttcatctcg tccgcaacga tagccttgat
     8701 atttggagtc agtttgtaga gcttatccac tgtctcttcc aactgctgcg gatccttgga
     8761 gttgaggctg tagccgaggg aattgagtcc tagtcccagc acctcacgcg ccccatcaaa
     8821 aagcatgata gaattcttat actccagctt ccaaaggtca tcccaatgct caggcgcttc
     8881 atctaccatg gtttcgttgt agacaattcc taaggttccc cagaagtaag ggatggagaa
     8941 tttattacct gggtcaaagg actggttgag aaactctggt ccgatatttt cgattccttc
     9001 aatttttgaa taatcaagcg gaaccaagag gtcttcgtcc ttcatcttgt taatcatgta
     9061 ttcacttgga atggcaatat cgtaggtcgt tccaccctgc tttatcttag tgtacatggc
     9121 ttcgttggag tcaaaagcct cgtactgaac ttgaattcct gtttcttctg taaactgagt
     9181 caagagttca ggatcgatat agtctcccca gttatagata accaattttt gactatctcg
     9241 actattgatt ttactatcta aatgagtcgc aattccccac aagacaagga taatcgctgc
     9301 aattcctgct aaaaatgaat agattttttt catgcttgct cctccttctc acgagagata
     9361 aagtaataac ctacaactag gataatacta aagagaaaga ctagagcaga aagggcattg
     9421 atttctagcg aaatcccctt gcgagcacga gagtaaatct cgactgatag ggttgaaaag
     9481 ccatttcctg ttacaaagaa ggtcacggca aagtcatcta acgaataggt gaaggccatg
     9541 aaataaccag caatgataga cggagtcagg taaggaagca tgatttcctt aaacatctga
     9601 aattgactag ctcccaagtc ataggccgca tgaatcatgt cgccattcat ttccttgagt
     9661 cgaggcaaga ccatcaagac cacgatagga atggagaagg ccacatgact agatagaacg
     9721 gtcaaaaagc caagtgaaaa cttgagttgg gtaaagagaa tcaagaagct agcaccaatc
     9781 ataacgtcag gcgcaaccat gaggatatta ttgagtgata gaaaggcttc ttggtatttc
     9841 ttacgagact ggtagatgta aatggcacca aaagtcccga taatggtcgc tatcaaggct
     9901 gataggaagg ccaagaaaaa tgtctgagcc aaaatcagca tgagtctccc atctccaaac
     9961 atggtttcaa agtgagtcca gctaaaacct gtaaagctat tcatatcatc accagcatta
    10021 aaggcatagc caatcaagta aaagataggc aggtagagga ccagaaagac cagtcccaga
    10081 taaaggttgg caaatttttt catcgttctc tcctttcctt agtcacccac atggtgatga
    10141 acatggtcag gatgagaatc acaccgatag ttgaacccat accatagttg tcattggtta
    10201 gaaaattctg ctcaatagcc gtccccaagg tgataacgcg gttcccacca atcaaacggg
    10261 tcagcatgaa gagactcaaa cttgggataa agaccgactg aaccccactt cgcacaccgt
    10321 tcatagatag agggaagatg acatgacgga aggtctccca cttagttgca ccaaggtcgt
    10381 aactagcatt gatgagatta ttatccatat cgtctaagac attgaaaatc ggcaaaatca
    10441 taaaggggag ctcgatgtag cttgcgacaa agataaagga aaaatcggta aaaagcaact
    10501 gttgtgaacc aattccgata aattccaaga attggttaat agagccattt tgaccaaaaa
    10561 tcccgataaa agcataggct ttaaggagca aattgatcca ggtaggaagg ataatcagca
    10621 tgagccagag ttgacggtgc ttgagacggg tcaaaaagag ggctgttgga tagctgataa
    10681 gcaaggttac aaaggtcaca atccctgcat aaagcactga gttgaaactc attttgaggt
    10741 aggtcaagtt ttgtgacgca aagtaagatt tataattttc taaactaaac tggccttcaa
    10801 tgttgaaaaa ggattgtccg aaaatcaaga ccaagggtgc caatacaaag agggcaatcc
    10861 aaagcatgta gggcactaca aagagtttag agcttgtttt cttcatctct ttcctcctcg
    10921 atcgcattga tcagacctgc ttcttgctct tcgatttcca cgtattcttc gatacgagca
    10981 tcgaactctt cttcggtttc attgagacgc atgatgtgga tgtcttctgg ttcaaagtcc
    11041 agaccgattt cctcacccac gatggcctta cgggttgagt ggatcatcca ttcatttcca
    11101 agttcgtcat aggcgataat ttcataatgc accccacgga agagctgggt atcgacctta
    11161 acttggagct tgccttcttc aggaagggta atgcgcaagt cctctggacg aataacgacc
    11221 tcaacaggtt catttggctt catcccacca tcaaccgctt caaagcgttt gccgttaaat
    11281 tcgaccaagt agtcctcaat catggtacct ggcaagatgt ttgactcccc gataaaggtg
    11341 gcaacaaagt ggttgattgg ctcatcgtag atgtccacag gggttccaga ctggacaatc
    11401 tcgccatcat tcataacgaa aatccagtca ctcatggcaa gagcttcttc ctgatcgtga
    11461 gtgacaaaga caaaggtaat gcccaatcgt tgttgtaatt cacgcaattc gtactgcatg
    11521 tctgttctca atttcaagtc cagcgctgat aaaggctcgt ccaacaagac cacacggggt
    11581 tggttgatga tagcacgggc gatggccaca cgctgacgtt gtcctccaga aagtttgcgg
    11641 atggaacgtt tttcataacc ttccaactga accatcttga gaacttccgc tacacgctgc
    11701 tcaatttctt tcttatcaat tttacgcaag cgaagtggaa aggcaacatt ttcaaacaca
    11761 ttcatatgtg ggaacaaggc ataggattgg aagacggtat gtacgtcgcg cttgttggtt
    11821 ggaatatcat tgatacgaac accgtctagc atgatatctc ctgtcgtcgc atccagtaaa
    11881 cctgcaataa tgtttaggat agttgatttc cccgaaccag atgcacctag aagggtgtag
    11941 aatttccctt cttccaactc aaagttgatg tctttgagaa ccttggtgtt gctgtcttca
    12001 aaaactttag agacgttttt gaattcgata attggttttt tcaattggca taaattcctt
    12061 ctttttcata gattaaccga tcggggctct gtcaggtccc cactacctct tgcagggagt
    12121 aaaaccacct gcatacatct tcgctaccga taggctttca cccaagatcc ggacttctct
    12181 ttcaagcgta atacctgagt gttccttgac tttttcgata accgattgga tcaagtcctc
    12241 gtagtctttg gccgttccat ctgcgacatt gatcataaat cctgcatgct tttctgacac
    12301 ttctacgcca ccgatacgat agcctttcaa gccagcttct gaaattaact gacctgcaaa
    12361 atgcccgact ggacgcttaa agaccgagcc acaagatggg tattccaaag gttgcttgag
    12421 ttcacgtagg tgcgtcaagc ggtccatttc ctgcttgata acctgatggg ttcctggagc
    12481 tagggcaaat ttaactgaca agacaactgc accagactcc tgaatagctg aatggcggta
    12541 accaaaagcc aagtctttag cagacagggt ttcgatttct ccatccttgg tcaagacctt
    12601 acaagactgc aagatgtgag caatctcgcc accataggca cccgcattca taaagacagc
    12661 accgccaacg cttcctggaa taccacaagc aaactcaaag ccagttaaac tatgacggag
    12721 ggcaatgcga gttgtttcaa tcaagttagc cccagcttct gcttcaatgg tatagccatc
    12781 aacagaaacg ttattgagct tgtcacacaa gatgacaaat ccacgaatcc caccatcacg
    12841 aacgatgata ttgcttgcat tgccaagaac catccaaggg atattttctt ggttggcaaa
    12901 tttcacaacg cgagccaact caaaacgatt tcgtggaaag accaaataat cagcctctcc
    12961 acctactttt gtataactat agctatgcaa gggttcctta aaacggatat caattccttc
    13021 taagatttca agcatttttt ctcttacaga catgtcactc ttccttttac aaaattcatt
    13081 ccattatacc atttttagag acatttgacg accataaaaa taccttgttt ggattttgca
    13141 taagaaaaag aggttccccc ctttttatga ttttttacaa aagatttcct tggttccata
    13201 ggcgaccaga acgagctcca gtgctagaat cacttcaacc aagactggat ttgtcaacca
    13261 gcctacttgg aaaagagatg gtgccagatc aaagaaggca tgcaagccat aggctgctag
    13321 gagataaatc catttcttct ggcgaacagc ttggtaaacc caaactgtca aaagtaattg
    13381 gaaaccaagc gccaagattc gctcaaaacc aagcaaataa atctgccaga ccgaaagtga
    13441 ctgaatggtt tttaacatat tttcagacag taattgcata acctgtggat tctgagtttg
    13501 aactgccgaa agaacgatgt aaagattgag taaactaata aggcctagaa aaatcaactc
    13561 caagccacca tgccctaggc cataggccaa ggcatctgcc ttttccaaac ttctcttttt
    13621 ctccaaccat ttgaagaaaa caagacgagc cgtttcctca aaaaatgctg ccatggctag
    13681 gccatagata atatagataa gcggatgatc ttgcaagagg gcaatactac cgtctttttg
    13741 aggatgcaaa atcaagatat gcaccagttt ttccaaaatc tgcgaagaga caaagaaagc
    13801 gactgcaccc aagcccaaga cagctagatt aatctggtat ttctttttgg caaaccaaat
    13861 gcttcctatc agaaaagcta gcaacagcaa catggtaata atgatatgaa tggtcatttt
    13921 cttctcctat tctgcctttt caatatcttt tttcatctcg tcaacattga acttagcaaa
    13981 caagtattga cggtcttgga ctgggaaacg ttggtccaac tggtcaactg ctcccacctc
    14041 gataatgcct tccttgatga caaaatccat gacatgtcca ccgaaggtca aatcatctga
    14101 tatgaagtgc agatggtagc ctgccacact gaccccatgg aaaatctcag gcgtccagaa
    14161 accaacaata gtccccgcaa cattgtcacg actatattcc ggttgatggg ttgcgacatc
    14221 agcaaacttg gtatcgggtg ttgacttagg aatcatacgc acatgcatat gtgaaaattc
    14281 cccccgaatc ttgatagagc ggaaaagatt ttccccatca taataagact caattcgttc
    14341 tttcaattcc ttgtctgtca tctcaaagcg ctggcggaaa atgacctctg cctgatgcgg
    14401 taccactgca gcgtaaggaa taagggcatc tggtgacact tccacaattt ctggctggtc
    14461 tcctgaccct ttggcctgat aagccttgcc atccaagaca atcaattccc catcaatgga
    14521 atccaaggtt cccaaaccaa ggtcaccatg ttctagcaat tctcctactg tcatagtacc
    14581 accataaagg ccagccatca aggctccaag agtattgtat tgaaataatt tcactggttc
    14641 ctgcacgttc ttatccattc actttcttgt ctgttattct ataaatctta ctcctaagta
    14701 taccacattt gcccctagat gtgaacgaga gaaacgctct agacattgcc aagaaggaaa
    14761 aaaaagggta caatgtaaca aaatcaaggg aggtctggaa tgaagaaaca aagcaagtac
    14821 aaagaggtcg tttcctatct gaaaaatggt atcgagtctg aacgatttcc gacgggtagt
    14881 cgcctgcctt ctatccgtca actgagcctt gactttcact gcagcaagga caccattcaa
    14941 cgagccctgc tggaattacg gcacgaacaa tacctctatg ccaagcctca gagtggctac
    15001 tatgtattag aacaagggca acatcaagac ctagaaatcg aggttaccga cgaacatgcc
    15061 agtgcctatg acgatttccg actctgtgtc aatgaaacct tgattggacg agaaaactac
    15121 ctcttcaact actatgacaa tcaagaagga ttagaagacc taagacagtc cattcacaaa
    15181 ctcctatttg agcaagctct ctactgcaag gctaaccaac tagtactgac ttctggaacc
    15241 caacaagcct tgtttatcct ctctcaaata tcctttccta gacaagccaa ggaaatcttg
    15301 gtggaacagc caacctacca tcggatgaat cgcctcttga ttgcacaggg gctggactat
    15361 caaacgattg aacgaggcat tgatgggatt gacttggagg agctggaagg ccacttcaaa
    15421 acaggaaaaa ttaaattttt ctacaccatt cctagatttc actatcctct gggacattcc
    15481 tattctgagc aagacaaacg atctattctt aacttagctg ccaagtatga tgtctatatc
    15541 gtagaggacg attatctggg tgatttggac tccaagaagg gccaaacctt ccactatctt
    15601 gatacagagg agcatgtcat ttatatcaag tccttctcga ccagcctttt tcctgccctt
    15661 cgtattacag cactcattct tccaaatgct atcaaagaag catttgtggc ctacaaaaat
    15721 atcctagact acgacagcaa cctcattatg caaaaggccc tgtcactcta tattgacagt
    15781 caattgtttg aaaaaaatcg tttggctcgc ttgaccaatc atgaatctta ccaaaaacaa
    15841 atcgaggaaa ggataactaa aacaccttgt ccccttcctc attatcccct acacgatggt
    15901 ttattgctag acctgagaca gtatcctaaa atcgccagtc tcaaacacag tcaactgggc
    15961 ttggacttct ttgaagaggc ctatttaagc acctgtcctt atcaatttgc caaggtgtcc
    16021 ctagacaatc tggaaaatgt tttaaactat ttaaaagcag aattggaatg acatccaact
    16081 ctgctttttc ttattcttca acttcagtta gacttgctgc tttttcaaga tagctttggt
    16141 aagttccttc attcttaagt ttttggatga ccttgtctac cacttctttc aaatcatcac
    16201 tattttttct aagagcaacg gcattggcgt cgccgtcctt catcttcaag ctgacagttg
    16261 cgacagctaa gccagcgttt ttagcagcat aactaagtgc aacaggctca tccatatgaa
    16321 cagcatctac ttttccagcc tgcaattcat tgactgcttc acccatatta gttagggaag
    16381 ttaattgagc ttttggcaat tgttccttga ccattgattc tggaacagtc cctttttggg
    16441 ctgcaatatt agcactttct aggctagtta aatccttgta tttttccaca tcagccttac
    16501 gaaccaagaa actaatcttg ttttcatagt atgggattga aaaatcaaag acttcttttc
    16561 tctcgtcagt agcactaatt cctgcaactg ctaggtcagc cttaccagtt tgaagactgg
    16621 tcaaaacatt gtcaaaactc atgcttgaga tttccaactt aaccccaagt tcatcagcga
    16681 tagcctgagc catgtcgatg tctgcaccga ctacctggtt ctttccatca accaatgatt
    16741 gaaattcaaa gggtgcatag tcaggactgg ttgccacaac taatttcccc ttttgcttaa
    16801 tggcctcaac agctgactga gaaccattag aacctgactg gcaagctact aagaagaaac
    16861 ttgcaagaaa attacataaa acaaatatcc atttttttga tttcataaat aaacaacctc
    16921 tctgttaatt ttgtat
//
LOCUS       DAVLZG010000048        16413 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLZG010000048 DAVLZG010000000
VERSION     DAVLZG010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16413
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.048"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..298)
                     /locus_tag="VYO72_001539"
     CDS             complement(<1..298)
                     /locus_tag="VYO72_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1707883.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKN"
     gene            541..834
                     /locus_tag="VYO72_001540"
                     /pseudo
     CDS             541..834
                     /locus_tag="VYO72_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            941..1292
                     /locus_tag="VYO72_001541"
                     /pseudo
     CDS             941..1292
                     /locus_tag="VYO72_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1568..2874
                     /locus_tag="VYO72_001542"
                     /pseudo
     CDS             1568..2874
                     /locus_tag="VYO72_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2914..3924)
                     /gene="tsaD"
                     /locus_tag="VYO72_001543"
     CDS             complement(2914..3924)
                     /gene="tsaD"
                     /locus_tag="VYO72_001543"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1707884.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3914..4351)
                     /gene="rimI"
                     /locus_tag="VYO72_001544"
     CDS             complement(3914..4351)
                     /gene="rimI"
                     /locus_tag="VYO72_001544"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1707885.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(4348..5031)
                     /gene="tsaB"
                     /locus_tag="VYO72_001545"
     CDS             complement(4348..5031)
                     /gene="tsaB"
                     /locus_tag="VYO72_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1707886.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            5209..5394
                     /gene="cibA"
                     /locus_tag="VYO72_001546"
     CDS             5209..5394
                     /gene="cibA"
                     /locus_tag="VYO72_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1707887.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            5396..5548
                     /gene="cibB"
                     /locus_tag="VYO72_001547"
     CDS             5396..5548
                     /gene="cibB"
                     /locus_tag="VYO72_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1707888.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            6366..6599
                     /locus_tag="VYO72_001548"
     CDS             6366..6599
                     /locus_tag="VYO72_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1707889.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6601..8280
                     /locus_tag="VYO72_001549"
     CDS             6601..8280
                     /locus_tag="VYO72_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1707890.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(8475..10388)
                     /gene="mnmG"
                     /locus_tag="VYO72_001550"
     CDS             complement(8475..10388)
                     /gene="mnmG"
                     /locus_tag="VYO72_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1707891.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWASFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(10398..10853)
                     /locus_tag="VYO72_001551"
     CDS             complement(10398..10853)
                     /locus_tag="VYO72_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1707892.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(10994..12115)
                     /gene="mnmA"
                     /locus_tag="VYO72_001552"
     CDS             complement(10994..12115)
                     /gene="mnmA"
                     /locus_tag="VYO72_001552"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1707893.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(12516..14258)
                     /locus_tag="VYO72_001553"
     CDS             complement(12516..14258)
                     /locus_tag="VYO72_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1707894.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPKPAPAPAPTPEAPAPAPKPAPAPKPAPAPKPAPAPKPETPKTGWKQENGMW
                     YFYNTDGSMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQYND
                     SWYYLNTNGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKV
                     NGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKWYYVNGLGALAVNT
                     TVDGYTVNENGEWV"
     gene            complement(14547..14825)
                     /locus_tag="VYO72_001554"
     CDS             complement(14547..14825)
                     /locus_tag="VYO72_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707895.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(14810..15049)
                     /locus_tag="VYO72_001555"
     CDS             complement(14810..15049)
                     /locus_tag="VYO72_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707896.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            complement(16182..>16413)
                     /locus_tag="VYO72_001556"
     CDS             complement(16182..>16413)
                     /locus_tag="VYO72_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707897.1"
                     /translation="VDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQ
                     KAGYLFSVLLLFSNFSVPFIKAKEYELFKNSK"
BASE COUNT         4717 a         3693 c         3056 g         4947 t
ORIGIN      
        1 tatttttaac gtgtaaggca gtttcaaaat tatttgaaca ttgagtacaa tcaacatagg
       61 caatatctaa atttttataa tcatcaataa cctttgaatc tctagatacg attatcaaaa
      121 taggatatag agacatcctt ctgatctgct ttttacaaag tccaattata tgcggatcta
      181 tacctccaca atgtccatta ttatacctaa ctataatatg agccgaaaac actatatcct
      241 taatgtctcc atatccatca gggatattaa tatttatttt tccacaacta tattgcattg
      301 taaccatctc cttaaacgac gcattatgat atttgataga gaaattttta tgaataactc
      361 aataatttta tagtaaatca tgcttatatc tcaaagatac ctattttatc ttgtctcgac
      421 cttctccaaa gaattgctat aatactatta caaatccatc tgcactacac ttcaaatttt
      481 agcactgtat aaaaacgttt caatacacta acttcaagaa aacttccact attaattgaa
      541 aaaattgata gagataaatt aaaaatctat attgaaactc atcccgatgc ttatttgact
      601 gaaatagctg ctgaattcaa ctgtcctcca acaactattc attacgctct aaaggctatg
      661 ggatatagtc taaaaaagag ccgtacctac tgcgaacaag acccagaaaa agtaaatcgg
      721 ttccttaaag aattgaatca cttaagctac ctgactccta tttatattta tgagacaggg
      781 gttgagacct atttttatct cgaatatgat cgagccttga gcaggcagtt agtctctctg
      841 gaagaagata taattatttg aattaagatc gagacaacgc acaccagaga ttgcgatact
      901 gttatagaag tactaatgcc cttttttgtt tcaatatact atggctccga tgacctataa
      961 agatacgatg acgagtgact ttttcgaagc ttgcttccaa aaattcttac tacctacttt
     1021 agatacacca tcccttatca ttatggacca tgcaaggttt cacagaatga acatgtgtaa
     1081 ggagcagggc atagactgtt accacttcct acctattcac ccgagtataa tcccattgag
     1141 aaaatatggg cttacatcaa aaacatctca gaataatatt gtcaaattac gatgcttttc
     1201 ttgaggcact tttgtcctat tcttgtttca gccgactata ctccgttatt gggcagctac
     1261 ggaacagtcg atgggacgat ggggggacat aaaaaaatcc tccagttttg ttttttataa
     1321 cagtatactg gagaattgac aatctcggta gatacctcgt tatagcgcgg ttacttatta
     1381 ggcagttaca aaacaactgt gaacagaaaa cattccagag tcagacaaga ctttggaatg
     1441 ctttggctct ataatttctg tagtgggtaa tcccacccca ggaattatag ggtcgtttct
     1501 tgtagaaaaa aagccccata tgacctataa tgaaaagcgt ctaaccaact cattagaaag
     1561 ggttcatatg gaacaactta agaataccac agatttgctc ggattggaag acaaaaatat
     1621 caaaatcttg tctgttctga aataccaaac ccatctagtc gttcaggcaa agttggattc
     1681 ccccgctcct ccttgtcctc attgtcaagg gaagatgatc aaatacgact tccagaaagc
     1741 ctctaaaatt ccgcttctcg actgtcaggg tttacccacg gtactgcatc tcaaaaagcg
     1801 ccgctttcag tgcaagaatt gccttaaggt ggtcgtttct caaacatcca ttgtcaagaa
     1861 aaattgccag atttccaaca tggtgagaca aaaaatcgct cagctcctcc ttgaaaagca
     1921 gtctatgact gagattgccc acagattggc ggtctcaact tccaccgtca tccgaaaact
     1981 gagggaattt aagtttgaaa ccgattggac caagttgcca aaagttatga gttgggatga
     2041 gtatagcttc aaaaagagca aaatgagctt cattgcccaa gattttgagt ccaaatccat
     2101 cctcgcaatt ttagacgggc gaactcatgc ggtgattcga aaccatttcc aacgctatca
     2161 gagagaggtt cgggagctgg tcgaggtcat caccatggac atgtacagcc cttattatcg
     2221 gctcgctaag caactctttc caaaggcgaa gattgttctt gaccgcttcc acattgtcca
     2281 acatctgagc cgagctatga accgagtacg aatccaaatc atgaaccaat ttgaccgaaa
     2341 atccttggag tatcgggcgc tcaagcgctt ttggaaccct cgctttttcg tttctaggct
     2401 cgggctaaat cagtccactg gactgattta ctacaccagt atagcttcaa gctctgtcag
     2461 aaacgattct atcagcccac gtttcgaatg cacttaaccc atcgggaagt acgagataag
     2521 ctgctttctt actctgaggg attacaggtt cactacgaac tctatcaact cctgctcttt
     2581 cattttcaag agaagaatgc cgaccatttc tttggattga ttgagcaaga actgccaacg
     2641 gttcatccgc tttttcaaac ggtcttttgg acttttttaa gggatagaga taagattatc
     2701 aacgcactta agctgcctta ttccaacgct aaacttgaag cgaccaataa tttgattaag
     2761 attatcaagc gcaaagcctt tggtttccgg aactttaaca attttaaaaa acggattttg
     2821 atgactttga acatcaaaaa agagagtacg aatttcgtac tctccagatt gtagcttttc
     2881 gcctacccac tacacttgac aaagagccac tctttattcc atggtatcaa aggcaagact
     2941 tggtttggca ttgaggtccc agcctgcgaa gttttctttg ttccactcgc tgacgctggc
     3001 ataggcaatc atacctgcat tgtctccgca gagtcgcaga ggggggatga taaccttgac
     3061 atctgtgatt tcggctgcta ggcgttctct gagaccttta ttggctgcca caccacctgc
     3121 cacaaccagg gttttaacag gatatttctc caaagccttc ttggtttttg ccatgagaat
     3181 gtccataact gctgcttgga aggaagcaca caaatcttct gtagacaggc tttctccctt
     3241 ttgctcggca ttgtgataaa gattgataaa ggcagatttc aaacctgaga aggagaactc
     3301 cagattatct tccttaatca tggcacgggg gaaatcataa atatcctgcc cctgatgagc
     3361 cagctcgtca atctcacgac ctgcaggata ggtcaagccc atgacacggc cgaccttatc
     3421 ataagcctca ccaaccgcat catcacgggt ttccccaaca atcttataat ctcctgcctc
     3481 cgaaacataa accaactctg tgtgcccacc gctaaccaag agggctagca agggaaactc
     3541 caaaggttcc acactttgag ccgccatgag atggccagcc atgtggttaa cgggaatcag
     3601 cggaagtcca tgtgcccaag caaaggcctt ggcagctgac aaaccaacta gtaaggctcc
     3661 gaccaagccc ggtccatagg taaccgccac agctgtcacg tcctcttctg taatccctgc
     3721 ttctgctagc gcctcctcga tacaggctgt aatgacctcg acatggtgac gactggctac
     3781 ttctggcact acgcccccaa aacgtttgtg actctcaatt tgactagcaa tgacattgga
     3841 caagagctca tcgtcgtttt tcaagacggc aacactggtc tcatcacagg atgtctcaaa
     3901 tgctaaaata tatctatcct tcatctattt ctctcttcat gataatggcg tcctcgactg
     3961 ggtcatggta gtaggctttt cgctcagcga tgaccgccat tttttctttc ttgtaaaatg
     4021 cttgcgctcg ttgatttgac tgtctaactt cgaggaaaat ttccttgtct gtcggcaatt
     4081 gagcaaacaa ggctgacgca attccctgac cctgacaggc tcctttgaca gcgatttgca
     4141 ggacttctgc ttcaaagaga gtctcctgaa cagttagaaa gccaatcact tctgccccat
     4201 cataggccag agcataccaa gtctggtctt gggacagatc tgcttggatt tgttctagtg
     4261 tccaaggact gactgggtaa acagctgcca tgacagcgta gatatcttga gccaaggcag
     4321 gttgctgttg gatacgtttg atttctatca taggcgttta atgtaagact caccagactc
     4381 ggtatggttc ttgagccagt tttcctctgc ctcaacacgt ttgaggtaat ttggcacaaa
     4441 atcatgcaag gagtctgctt ccttgtccca ggccaaaaga gctagattag ctgcattggg
     4501 caatgtttct ttgtaatcag tccttggcaa gtgtttttga atctgctcaa caaaggggcc
     4561 aacttctccg acaaaggtta cctgactagc gcccttgatt agctcaatga ctcgctcaaa
     4621 aggcagatgt gcttctgcca tgacaggttt ggcattttca taaaatcctg cataaacatt
     4681 attgcgacgc gcatccatca aaggaacaaa caaaccttct tgttgatatg gcactagagc
     4741 caagagacta gacataccaa ccaactcaat gttcagggtg taagctaagg tcttagcagt
     4801 tgctaccgca attcgcaagc ctgtatagct acccggccct tcagctacca cgattcggtc
     4861 caaatccttg ggtgtccaat ccaaacttgc catcaaaaaa tcgatggcag gcataagagt
     4921 aatactgtga tttttcttaa tattaatcgt cgtctcggca agaacctgct tatcctctaa
     4981 aatagccaga gaaagagcct tgctggacgt atcaaaagct aatactttca taacacattc
     5041 ctatcttttt gtctgcttac tattatacta caaaagctgg cacatgggaa ttttctttgc
     5101 ccccagacaa gagtgccctc acttaactaa aaataattta aaaaaatgct cacttttcct
     5161 tttcttttcc gaatataaaa gtgaacaaga aaaaaggagg aaagttcaat gacaaatttt
     5221 gacattcttg acaatcaatt tttatcctta tctgaaaatg aattatcaga tattgatggc
     5281 ggtctcgctc ccttggttat ctttggagta gcagtatctt ggaaggctat tgcaggtgga
     5341 acagcactta taggttctgg tttggcagct ggttattttt taggaggaga ttaatatgat
     5401 gaaagatttg aacaattatc gtgaaatttc taataaggaa ttgcaagaaa tcaagggtgg
     5461 ctttggtgtc ggtgttggta tcgctttatt tatggcaggt tataccattg gaaaagacct
     5521 tcgtaaaaag tttggtaagt catgctagat aagaaacaca tttttagaag gataaatttt
     5581 attgtcttca tctcttacag tttgctcagc attctcaatg atttgaacat tactaccatc
     5641 cctttaccat tcgatttatc tgtttgtatt gttttatttt tatgcttcaa ctctattttt
     5701 gagtagaaca atgactccca taaaaataat aagctttgaa aattccattg tcatgtcatg
     5761 ttagaaaaat gcaaagacca cctcatcttg atagatgggg tggaattttc gtgtcgtaaa
     5821 tctactatct ctacattccc aaacaaaaaa aaccagcata agcagggcat ctaagcattt
     5881 aatccaaagt aaaatacaaa ccaaacgaca taggtcacga ggaggagaaa aagcgagtag
     5941 agagtcacaa aggtaatttt ccacaagaac ttggtttgtc atcgttccag tttggcaaat
     6001 agaagatttc ctccataaac gcaagcaaca aaaacgataa aagctagcaa acgaactccg
     6061 atagcaaaag caaataagtt atacataggg caacctcctt gacttaaaat ctatatggaa
     6121 ttatgacaag taataaactt cacttccgtt atcaacataa cacattttct ttatttttgc
     6181 aaacgattac caaagaaatc gccccctaac tttctcgttt ccgtctttta ctaatttttc
     6241 attttgtggt ataattgaaa taattgtaac gaatcaaggt caatctagac acaaaatgga
     6301 atgaaatcaa gcaaatatct gctaaaagtt tggaataagc tgacctgtaa atagaaagga
     6361 actatatgat ttacaaagtt ttttatcaag aaacaaaaga acgtagccca cgccgtgaaa
     6421 caacacgcgc gctttaccta gacatcgatg ccagctcaga acttgagggt cgcatcactg
     6481 ctcgccaact tgtcgaagaa aatcgcccag agtacaatat cgaatatatc gaactcttgt
     6541 ctgacaaatt gctcgattac gaaaaagaaa ctggcgcctt cgaaatcacg gagttctaat
     6601 atggcctaca ctcttaaacc tgaagaagtc ggcgtttttg ccatcggtgg tctaggagaa
     6661 atcgggaaaa acacttacgg aattgaatac caagacgaga ttatcatcgt cgatgctggg
     6721 attaaattcc cagaagatga cttgcttggt atcgactatg tcattcctga ctactcttac
     6781 atcgtagaca atatcgaccg cgtcaaggct gttttaatca cacacggaca cgaggaccac
     6841 attggtggga ttccgttcct actcaagcaa gcaaatgtcc ctatttatgc tggaccgctt
     6901 gccttggctt tgatccgtgg gaaactcgaa gaacacggcc tcttgcgcaa cgccaaactt
     6961 tacgaaatca accacaacac cgagttgacc tttaaaaatc tcaaggcaac tttctttaga
     7021 acgactcact ctattccaga gcctttgggg attgtcattc atactcctca agggaaaatc
     7081 gtctgtacgg gtgactttaa gttcgacttt actccagttg gagaacctgc ggacttgcat
     7141 cgtatggctg cgcttggtga agaaggcgtg ctctgtctcc tgtctgactc gacaaatgcg
     7201 gaagtaccaa cctttaccaa ctctgaaaaa gtcgttggtc agtccattat gaagattatc
     7261 caaggtattg aaggacgtat catctttgca tcctttgcct caaatatctt ccgtctccag
     7321 caggcaacag aagctgctgt taagactgga cgcaagattg cggtctttgg tcgttctatg
     7381 gaaaaggcca ttgtcaacgg aatcgatctt ggctacatca aagctcctaa gggaaccttt
     7441 atcgagccaa atgaaatcaa agattatcct gcaggagaag ttcttatcct ctgtacaggt
     7501 agtcagggtg agcctatggc agccctctct cgtatcgcca acggaaccca ccgtcaagta
     7561 caattacaac caggtgatac cgttatcttc tcttctagtc ccatccctgg aaacactact
     7621 agcgtcaaca agctgattaa catcatttct gaagctggtg tcgaagttat ccacggtaaa
     7681 gtgaacaata tccatacatc tggacacggt ggtcagcaag agcaaaaact catgctctgc
     7741 ttgattaagc caaaatactt catgcctgtc cacggtgaat accgcatgca aaaagtccac
     7801 gctggactag cagtggatac tggtgttgag aaggacaata tctttatcat gagcaatggc
     7861 gatgtgcttg cccttactgc tgactcagct cgtatcgcag gtcatttcaa cgcccaagat
     7921 atctatgtcg atggaaatcg tatcggtgaa attggcgcag ctgtcctcaa agatcgtcgc
     7981 gatctatctg aagacggtgt cgttctggca gtcgcaactg ttgacttcaa atcgcagatg
     8041 attctatctg gtccagacat cctcagccga ggctttgtct acatgagaga gtctggcgac
     8101 ttgattcgcc aaagccagcg tatcctcttc aatgccattc gtatcgcact gaaaaataag
     8161 gatgctagcg tgcaatctgt caatggtgcc attgtcaacg ctattcgccc cttcctctat
     8221 gaaaataccg aacgtgaacc gatcatcatc ccgatgatcc tcacaccaga tgaagaataa
     8281 agcaagaaaa cagccccgtc ttcggagctg tttttctcta tgctttcttt tgagattaaa
     8341 actcaatgaa aatcagacca gaaggctagg aaaatgcata acttgagtta gctcccatag
     8401 ttcggggaac tatgggaggt tggagatgaa tcaaagccaa gctttgaact cattcgtaag
     8461 aagccgacga cgtatcattt tgatttttga agagttttag aaatactacg atttttacct
     8521 tccagataca ccatcaaaat agaaatatct gctgggttta ctcccgaaat acggctggct
     8581 tggccgatgg tttctggatt gatgagtttg aacttctgac gagcttccgt cgcaatagaa
     8641 tcgatgtcat cccagtcgat attggctgga atgcgttttt cttccatacg tttcatcttg
     8701 gcaacctgat ccatggcttt ggaaatatag ccttcgtact tgatttctgt ttcaatcaat
     8761 tcgataatct tgtcatccaa gtcttctgca gctggtccga tgaaggccac cacatcttgg
     8821 taagaaactt ctggacggcg aaggaattcc ttggctgtca ccgcatctgt caacggcttg
     8881 aagcccattt cctcaacctt agcattggtt tccttgactg gcttgagttt gatactgtct
     8941 aggcgtttca tctcattatc aaattgattt ttcttgattt caaaactagc ccagcgttca
     9001 tcatccacaa ggccaatctc gcgtcccatc tcagtcaagc gcatatcagc attgtcatga
     9061 cgaagaatga gacggtattc agcacgactt gtcaagagac ggtagggttc aatggttccc
     9121 ttggtcacca agtcgtcgat catcaccccg atataaccgt cactgcgctt caaaatcaac
     9181 tcaggcttgc cttggatttt cagagccgca ttgatacccg cgataatccc ttggccagca
     9241 gcttcttcat aacctgatgt tccatttgtc tgaccagcag tgaagagacc tgagattttc
     9301 ttggtttcca aagtcgcacg caactgatga ggcaagacca tatcatactc aatagcataa
     9361 cctgtccgca tcatctctgc attttccaaa cctttgatgg aatgaaccaa gtcacgctgg
     9421 acatcctcag gcagactggt tgaaagtcct tgaacataga cttcctcagt attgcgccct
     9481 tctggctcaa ggaagagttg gtgacgttcc ttgtccgcaa agcgcacaat cttgtcttca
     9541 atcgacggac agtaacgagg ccccactccc ttgaccacac ctgtaaacat aggcgcacgg
     9601 tggaggttgt tttggataat ctcatgactg gtaccattgg tgtaggtcaa ccagcatggt
     9661 acttggtcct tgacataatc ctcatcacgt gaagtgtatg agaagtgatt aggtgcttca
     9721 tctcctggtt ggatttctgt cacgtcgtag ttgatagaag aggccttgac acgtggaggg
     9781 gttcctgtct tgaaacgacc gatttcgaga cccagttcct tgagattgtc agctaggtta
     9841 atagaagcca agctgtggtt aggacctgat gagtacttga ggtctccgat gataatttcc
     9901 ccacggagag cagtccctgt cgtcacaata acagccttag cagcatattc ttgatgggtg
     9961 gctgtacgca caccgacaac cttaccatct tccaccaaaa tctcatcaat catggtttga
    10021 cgaagggtca gattttcttg attttcaact gtcttgcgca tttccttaga gtaaagttcc
    10081 ttgtcagcct gcgcacgaag agcacgaaca gctggcccct tccctgtgtt gagcatcttc
    10141 atctggatgt aagtcttgtc aatagtcttg gccatctcgc caccgagggc atcgacttca
    10201 cgcacgacaa tccccttggc agaaccaccg atagagggat tacaaggcat gaaagccagc
    10261 atttcaatat tgatggtcgc aagcaggacc ttacagccca tacggctagc ggccaaggaa
    10321 gcctcaaccc cagcgtgtcc cgcaccaatt acaataatat cgtattcttc agtaaaatga
    10381 taagtcatgt ttctctccta ttcctcaaga tgaatgtgtc ttagttggcc ttcccaatct
    10441 ggtagggctg tttttaaaaa ggctggaact agctggatat cctcaagctt atccaagtca
    10501 atccactcac agggctgcct tttctcatct tcctgcatgg tcaacggggc atcttcaagc
    10561 aaatccacca gataatgaaa ctcgatattg tgataggaaa cgccgtccac ttcaaaacga
    10621 ttttcaacca caaaagctag ctgcccagct tgagctttaa cacccagttc ttccttcact
    10681 tcacggacta ccgcgtcttc cgttttttcg ttaacttgaa tcgcaccgcc gataatgtaa
    10741 tacttgccct tgtctttggt gactagaagc ttgtgatttt ggacaatcaa ggctgtcgcc
    10801 cgaacaccaa aaaccgtatt gtctactttt gtccgaaagt cttgttgagt cattcttgtc
    10861 ctttccctta aacgacacaa aaacagtcaa aactccaaag aagtgcagga caaaaaagcc
    10921 tgcaacatcc atgagctttg accatcattt ctattgctgt tattattgta gcaaattgag
    10981 aaaatttgtc aatctaaatg tactgacaaa cttgtccatc gcggtaagca ttgtcaatca
    11041 aaccgccacc tagacactct tcgccatcgt aaaagacaac tgcctgtcct ggtgtaatcg
    11101 cgcgttgtgg ttccgcaaag ataacttctg ccttgtctcc tttgacatgg acggtcacct
    11161 tagagtcagg ctgacggtaa cggaatttag ccgtacattc tagcgtaaac tcttctggca
    11221 tttcacgagt aaagtggact tggctagcct ctaggctggt tgacatgagc gaatcatggt
    11281 agaaaccttg gcctacatag agaatattct tgcttagatc ttttccgaca acgaaccaag
    11341 gggcattgtc accaccgtgt tgcccaccga taccgagtcc gccacgctga ccgattgtat
    11401 agtacataag accagcatgc tcgcccatat cacgaccatc cacagtcatc atacgaccag
    11461 gctgagctgg caggtagttg ctgagaaagt ttttaaagtt cttttctccg ataaagcaaa
    11521 tccctgtcga gtctttcttc ttagcagtcg aaagacctgc ttcttctgct agttttcgaa
    11581 cttcaggctt tttcaaatgt cctagtggga acatggtttt ttgaagttgt tcttgcgaaa
    11641 gttggctgag gaaataggtc tggtccttgc cattgtccac gccacgaagc atgtgaacag
    11701 tgccatcctc atcacgcgcc actcgagcat aatgcccagt cgctacatag tctgccccca
    11761 aggttatggc atagtccaaa aaggccttga acttgatttc cttgttgcac ataacgtccg
    11821 gatttggcgt gcgccctgca cggtattccg ctaggaaata ctcaaaaacg cggtcccagt
    11881 actctttttc aaaattgaca gagtagtagg gaatgccaat ctggtctgcc accgcaacca
    11941 catccttgta atcttcggtc gccgtacaga cgccgttttc atctgtgtca tcccagttct
    12001 tcatgaagat accgatcaca tcgtagccct gctccttgag caaaagagcc gtcaccgacg
    12061 aatcaacacc accactcatc cccacgacaa cacgtgtttt agagttatca ctcatggtaa
    12121 gtctcccatc tattcgttta ttcacgattg aaggtcgtgt gtgcttcacg attgaaggtc
    12181 gcttgagcag tattcattat aacacgcttg gttagagaag acaaggaaga gcttaaaaat
    12241 tgttttttaa aacttatagt caatatacag attatgtgaa tgatgtgagt ataccttctt
    12301 cttatcttca ttcaaataac tataataaat aaaacaaccc attttctcta atctattttt
    12361 caagttagag aaaaggagtc gtttttttaa tgacatttcc tgaaatcata agataggtac
    12421 ctaaagaata cgaacataaa tctattcaat cgaaccttat ctttgtttca aaattaaaat
    12481 gtcaaatgtt cttaacatga tttaatttaa tcggcttaaa cccattcacc gttttcattg
    12541 acagtatatc cgtctacagt tgtgttgact gcaagggcac ctaagccatt gacatagtac
    12601 catttatctg atactttgaa ccattggttt gctttcatag cacctgatgc ttcaagatag
    12661 taccaggtat ctccatcttt cacccaacct gttgccattg aaccgttagc gttgaggtag
    12721 taccatgaac cgttgacttt agcccaacct gttgccatag cgccgttagc gtttagatag
    12781 taccatgaac cattgtattg gagccaacct gtcgccatag cgccattgct gttgaggtag
    12841 taccatgagc cattgtattc tagccaacct gtcgccatag caccattagt attgaggtag
    12901 taccatgaat cattgtattg gagccatcct gtcgccatag cgccattgct gttgaggtaa
    12961 taccataagc cgttgacttt agcccaacct gttgccatag caccattagc gttgaggtag
    13021 taccatgagc cattattttg tagccagcct gttgccattg aaccatccgt attgtagaag
    13081 taccacatac cattttcttg tttccagcct gtttttggag tttctggttt aggagctgga
    13141 gctggtttag gagccggagc tggtttagga gccggagctg gtttaggagc tggagctggg
    13201 gcttctggag ttggagctgg agctggggct ggtttaggag ccggagctgg agtttctggc
    13261 tcatcaactg ctttcttaag gtcagcttca gtattttcta attcagcttt tttagcatct
    13321 aagtcttttt tagctgcaac aagatattgt tcagcttgct caccgtctga gtttttgaaa
    13381 tcttctacat ctttttcaag ttttgcaatt tcagcgtcta actcatcaat cttatcactc
    13441 aactcttcaa gttttgatag tttagctttt ttggcatcca atttagattg aagaggagca
    13501 cggagacctt ctttaatata atcttctgag tcagactcat caatctcttt gagctctttt
    13561 tctagtccct gaacttcata ttccaactca gcgattttag cttcaagagc atatttttca
    13621 gcatccactt tttgtttggc ttcaacagct tttttctcag cttcttctgc ttttgcttta
    13681 gcttctgcta cttttttagc aagttctggt tctttttttt cagcctgttc tgcttttttc
    13741 ttagtctcag ctaacttatc tgcttcagga actacttttg cttgttcctt attgaaattc
    13801 gcttccgcct ctttttgttt taatgttacc tcatcaatat gagctaatgc atcttttaat
    13861 ttctgttgag cggcattttt cttattgttt ggacttttgt tcaattgttc ttgtgcttct
    13921 cggagtttta aatacgcctt ttgaactgcc acattcgctt tttgacgctc ttcatccgct
    13981 ttttgaacaa gctttgcttt ctcttcagtt ttcttttgat cgtcttcata ttttttctga
    14041 gcagcttttg cttcttctaa atctttctta gcttcttcgt attctttctt agcagcttca
    14101 gattttttca ttgctgcatc atagtctctc tcagcttgag actgcttagc tacgggagct
    14161 tcttctgctc ttacaacagt aggctgagac gcaacaaaac cagcccctaa gatagcgacg
    14221 ctggctagac ttgttaaaat catttttttc ttattcatct aaatttacct cttttctgat
    14281 agtcattttt agactatact tatattaagt atactccccc cgtaaatatt tgtcaaatgt
    14341 tttatattac atttttatta caaatttcta tatcataagc ttctactcca aaaaatagat
    14401 aaagatacta cttttgccct tttcgattct ctttttaaac atagcatcat cttccttcat
    14461 tcctataaaa acatttccga tgagagagct tgttttttaa tttcgttaaa caacaaaaaa
    14521 cgcaagctta agcctgcgga caatctttat agccatttca tttctttcac atctgtttta
    14581 cgaactttag catatttctt agcgcttgta aaatgtagag taactgattt aaatactccg
    14641 cttttgtctc ttcgtaaacc taaaactgcg gatcttttat ttttatcctc aaaaaatatg
    14701 acgtccaatt tcatagtatt tttagataaa tccctagcta cgatgcaaca acttattatt
    14761 ttagaataga aaatatcacc gataaactca tataaagata tcctttcgat tacatcattg
    14821 tacataggat atttctaaaa tcttctaaaa taaaaacacc agcttgaata gcaggttttg
    14881 tttgactagc ataatctcgt gtgattttgt ataagtcaaa taaatgatgt aaatcagtca
    14941 agcaaaaatt cactttgaaa atctctaaat acttataatt cgttgatact tgacatgttt
    15001 ttccattgaa tctttcttga tagtccaaaa tacaatcaag taatttcaac gacaaactcc
    15061 atattttctc aaaataaaaa agcacggggc agttctcact actgcccaaa gtggttgatt
    15121 agagtcggct tctctaactc cctatgttgt gcttattagg cttatcgcaa gggaacagtt
    15181 tttagctctg ccaagccaca tagtgtgctt actactatgt gtccatgtca ccatgaattg
    15241 ccgaacggtt taacgagaaa gtatagtaga ttgaaacaag atgtgaacaa atcgattagg
    15301 aaagtcaaat taatttctag aaatatttta acagtcataa cggactattc cagattcaat
    15361 ctactatatt acttttaggt ttatcccaac tcaattatga catttttttc aaaagtcaat
    15421 atatctcact cttttcaacg acaagaaaga ggctgataat cgaccaacct ctgtttttag
    15481 atacagttca agtccaaact attctttata gaaaagtccg ataaattcga gcaatagtta
    15541 acatacttac aaatataact cccaaaatag ataacactat tttcacaaaa ctcagttccg
    15601 aacctatgac atatatatga aaaagaaggg ctagtcctac acatatatac aataagtagc
    15661 caacaagttt tatctcacca attcctgcaa aaaaatgttt catgtgacga ttctccattt
    15721 actccattaa atcagtttta ttttagacta tcataacaca atcacctctt caataaaaac
    15781 catttgcgaa atactattct gaagcattga tagctcagat ttctcagaat agagctgtcc
    15841 taactatcga gcagctcaaa tacatatata tgagcaattc taagcctaga attgctataa
    15901 aataaatgtt tccaggctat tctaagtctt tgactgctta aaattttaca ttctgaagga
    15961 ttctaaagct agaacagctc aaaatcacga gaactaaggt attcgaaact tcagagtaat
    16021 acaatcccca taggaattct ccattcttat taagcatgat taaaatgtaa tcctaacaag
    16081 tgatcctcga ctgtgtttgt agcacttagt tacctagata agactatttc cctttatcat
    16141 atctgatttt aagccgttct aagatttaac ctatgtttct attacttgct atttttaaat
    16201 aattcgtatt cctttgcttt gataaatgga actgaaaaat tagaaaaaag aagtaaaacc
    16261 gaaaacaaat agcctgcttt ttgaatcact aaaagatatc ctaaaaataa gtaagctata
    16321 acatccaatg cgaaaagaaa aaatattctc ctcttcatta aagtacttgt gtcaaataat
    16381 ctgatgaata aaaattttat cgtagtatct aca
//
LOCUS       DAVLZG010000049        16186 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLZG010000049 DAVLZG010000000
VERSION     DAVLZG010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.049"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..957
                     /gene="lytB"
                     /locus_tag="VYO72_001557"
     CDS             <1..957
                     /gene="lytB"
                     /locus_tag="VYO72_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1707898.1"
                     /translation="WVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNK
                     NAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTE
                     DLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGF
                     KLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLL
                     AHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYID
                     RGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1018..2673)
                     /gene="pavA"
                     /locus_tag="VYO72_001558"
     CDS             complement(1018..2673)
                     /gene="pavA"
                     /locus_tag="VYO72_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1707899.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2778..3275
                     /gene="ybeY"
                     /locus_tag="VYO72_001559"
     CDS             2778..3275
                     /gene="ybeY"
                     /locus_tag="VYO72_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1707900.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3256..3651
                     /locus_tag="VYO72_001560"
     CDS             3256..3651
                     /locus_tag="VYO72_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1707901.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3668..4567
                     /gene="era"
                     /locus_tag="VYO72_001561"
     CDS             3668..4567
                     /gene="era"
                     /locus_tag="VYO72_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1707902.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKIPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4616..5440
                     /gene="mutM"
                     /locus_tag="VYO72_001562"
     CDS             4616..5440
                     /gene="mutM"
                     /locus_tag="VYO72_001562"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1707903.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5440..6045
                     /locus_tag="VYO72_001563"
     CDS             5440..6045
                     /locus_tag="VYO72_001563"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1707904.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6032..7231
                     /locus_tag="VYO72_001564"
     CDS             6032..7231
                     /locus_tag="VYO72_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1707905.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7231..7380
                     /gene="rpmG"
                     /locus_tag="VYO72_001565"
     CDS             7231..7380
                     /gene="rpmG"
                     /locus_tag="VYO72_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1707906.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7420..7653
                     /gene="secG"
                     /locus_tag="VYO72_001566"
     CDS             7420..7653
                     /gene="secG"
                     /locus_tag="VYO72_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1707907.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7755..10109
                     /gene="rnr"
                     /locus_tag="VYO72_001567"
     CDS             7755..10109
                     /gene="rnr"
                     /locus_tag="VYO72_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1707908.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYLEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRDSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10072..10539
                     /gene="smpB"
                     /locus_tag="VYO72_001568"
     CDS             10072..10539
                     /gene="smpB"
                     /locus_tag="VYO72_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1707909.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10555..11415
                     /gene="tehB"
                     /locus_tag="VYO72_001569"
     CDS             10555..11415
                     /gene="tehB"
                     /locus_tag="VYO72_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1707910.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11488..12441
                     /gene="coiA"
                     /locus_tag="VYO72_001570"
     CDS             11488..12441
                     /gene="coiA"
                     /locus_tag="VYO72_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1707911.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIQQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12460..14262
                     /gene="pepF"
                     /locus_tag="VYO72_001571"
     CDS             12460..14262
                     /gene="pepF"
                     /locus_tag="VYO72_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1707912.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14264..14977
                     /locus_tag="VYO72_001572"
     CDS             14264..14977
                     /locus_tag="VYO72_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1707913.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEEFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15044..15985
                     /gene="prsA"
                     /locus_tag="VYO72_001573"
     CDS             15044..15985
                     /gene="prsA"
                     /locus_tag="VYO72_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1707914.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16102..>16186)
                     /locus_tag="VYO72_001574"
     CDS             complement(16102..>16186)
                     /locus_tag="VYO72_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1707915.1"
                     /translation="IDYYNNKRIKVKLKGLSPVQYRTKSFR"
BASE COUNT         4876 a         3032 c         3636 g         4642 t
ORIGIN      
        1 tgggtctacg attctcatag tcaagcctgg tactacttca aatctggtgg ctacatggcg
       61 aaaaatgaga cagtagatgg ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa
      121 gctacaaata aaaatgctgc ttactatcaa gtagtgcctg tcacagccaa tgtttatgat
      181 tcagatggtg aaaagctttc ctatatatcg caaggtagtg tcgtatggct agataaggat
      241 agaaaaagtg atgacaagcg cttggctatt actatttctg gtttgtcagg ctatatgaaa
      301 acagaagatt tacaagcgct agatgctagt aaggacttta tcccttatta tgagagtgat
      361 ggccaccgtt tttatcacta tgtggctcag aatgctagta tcccagtagc ttctcatctt
      421 tctgatatgg aagtaggcaa gaaatattat tcggcagatg gcctgcattt tgatggtttt
      481 aagcttgaga atcccttcct tttcaaagat ttaacagagg ctacaaacta cagtgctgaa
      541 gaattggata aggtatttag tttgctaaac attaataata gccttttgga gaacaagggc
      601 gctactttta aggaagccga agaacattac catatcaatg ccctttatct ccttgcccat
      661 agtgccctag aaagtaactg gggaagaagt aaaattgcca aagataagaa taatttcttt
      721 ggcattacag cctatgatac gaccccttac ctttctgcca agacatttga tgatgtggat
      781 aagggaattt taggtgcaac caagtggatt aaggaaaatt atatcgatag gggaagaact
      841 ttccttggaa acaaggcttc tggtatgaat gtggaatatg cttcagaccc ttattggggc
      901 gaaaaaattg ctagtgtgat gatgaaaatc aatgagaagc taggtggcaa agattagtac
      961 tataagtgaa tatgatttga gtgaatagta agttaaaaat cctgatttca agtaaaatca
     1021 ggattttttc atggatgcaa tttttttgga gtctggtgtg acgcggaggg tcttttgtcc
     1081 tgtgtaagtg acaaagccgg gttttccacc agttggttta ttgagttttt tgacttcaat
     1141 catatctacc tgcaccagat tcgacaggcg cccttgagag aagtaggcag ctaactctgc
     1201 tgcgtctgtc ttgactgcat cagatgggtc aagatttcct gagatgacaa catggcttcc
     1261 aggaatgtcc ttagcatgga accaaagttc ctccttgcgg gccattttaa aggtcaattc
     1321 ctcattttga agattgtttc gtccgacata gatgatggtt ttgccatcgc ttgctagata
     1381 ttgttctagt tttttgcgtt tctggatttt ctcccgttgt cttctgcgga taaaacctgt
     1441 ttgaatcaat tcttcacgga tttcagcgat ttcttccagt ccagcttggt tgaggacggt
     1501 ttctacactt tccagataga gaatagtggc tttggtttct tcaatcaaat cagtcaagta
     1561 tttgacagct tctttgagtt tctgataccg tttaaaatag cgttgggcat tctggttggg
     1621 agtcagagcc ttatcaagcg caatcatgat aggttggttg gtatagtagt tgtctaggat
     1681 aacctggtct tggtcgttag gcacttggtg taggaaggtt gtcagcaatt ctcctttttg
     1741 acgaaattct tcagcgttgt ctgtcgccag taactctttt tcctgttttt tgagtttgtg
     1801 tcggtttttc tgaagttcat tttcaacacg acgaatcagt tcactggcct gctgtttgac
     1861 gcggtcgcgc tcagccttat ccttatagta ggtgtccaac aaatcagaaa gatttgcaaa
     1921 aggctctccc acctgatttg caaaaggaac tggactgaag gaagtctcag tcaagcatgg
     1981 cttggtttct tgattgaaaa aatttcggaa agcggaaagt ttttcactaa ccagtatcct
     2041 ttccaattca tttgcagtat cgcgtcccag accttgaaag aggctttgaa gattttttgc
     2101 tgttagttct tgggtttgca ggatttcaaa gagcttttca tctttgatag taaaaggatt
     2161 gagagattct gtacttggcg gagcgatata ggtcgatcct ggaagtaagg tgcggtagct
     2221 attttgtgaa aaaccgacgt gtttgataac ttcgaggatt ttatgactgc ttttatcgac
     2281 cagtagaata ttactgtgtt tccccataat ttcaataatc aaggtagcct ggatatggtc
     2341 tccaatctcg tttttattgg aaactgtcat ttccacaata cggtcatttt ccacttgctc
     2401 aatcgactca atcagggccc cctgcaaata ctttctcaaa accatgataa aggtagaagg
     2461 ttgggctgga ttttcaaaag tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc
     2521 agaaaggagc aggcgatggc tttggcgatt gctgcggatt tgcaagacca actcttgttc
     2581 aaaaggctga ttgattttct ggatgcgacc attcactaat tcgcttcgca attcctcaac
     2641 tatgtggtgt aaaaaaaatc catcaaatga catcgttctc tccttgtgat tgtattccat
     2701 agtattatat caaaaaggta gaataaaatc atggaaatgt ggtataataa agccaagtaa
     2761 agagaaacga gaagcacatg tatattgaaa tggtagatga aactggtcaa gtttcaaaag
     2821 aaatgttgca acaaacccaa gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag
     2881 acaaggagat ggcagtcact tttgtgacca atgagcgtag tcatgaactt aatctggagt
     2941 accgtgacac cgaccgtccg acagatgtca tcagccttga gtataaacca gaattggaaa
     3001 ttgcctttga cgaagaggat ttgcttgaaa atccagaatt ggcagagatg atgtctgagt
     3061 ttgatgccta tattggggaa ttgttcatct ctatcgataa ggctcatgag caggccgaag
     3121 aatatggtca cagctttgag cgtgagatgg gcttcttggc agtacacggc tttttacata
     3181 ttaacggcta tgatcactac actccggaag aagaagcgga gatgttcggt ttacaagaag
     3241 aaattttgac agcctatgga ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg
     3301 atatccagtt tagaatttgc tttgacaggt atttttactg ctatcaagga agaacgaaat
     3361 atgcgaaaac atgcagtgac ggctctagtg gttatccttg caggttttgt ttttcaggtg
     3421 tcacgaatcg aatggctctt tctcctattg agcattttct tggtagtagc ctttgagatt
     3481 atcaactctg ctattgaaaa tatggtggat ttggccagtc actatcactt ttccatgctg
     3541 gctaaaaatg ccaaggatat ggcggctggt gcggtattag tggtttctct tttcgcagcc
     3601 ttaacaggcg cattgatttt tctcccgcga atctgggatt tattatttta aacagtaaga
     3661 ggaaattatg acatttaaat caggctttgt agccatttta ggacgtccta acgttgggaa
     3721 gtcaaccttt ttaaatcacg tcatggggca aaagattgcc atcatgagtg acaaggcgca
     3781 gacaacgcgc aacaaaatca tgggaattta cacgactgat aaggagcaaa ttgtctttat
     3841 cgacacacca gggattcaca aacctaaaac agctctcgga gatttcatgg ttgagtctgc
     3901 ctacagtacc cttcgcgaag tggacaccgt tcttttcatg gtgcctgctg atgaagcgcg
     3961 tggtaagggg gacgatatga ttatcgagcg tctcaaggct gccaagattc ctgtgatttt
     4021 ggtggtgaat aaaatcgata aggtccatcc agaccagctc ttgtctcaga ttgatgactt
     4081 ccgtaatcaa atggacttta aggaaattgt tccaatctca gcccttcagg gaaataacgt
     4141 gtctcgtcta gtggatattt tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc
     4201 tgatcaaatc acagaccatc cagaacgttt cttggtttca gaaatggttc gcgagaaagt
     4261 cttgcaccta actcgtgaag agattccgca ttctgtagca gtagttgttg actctatgaa
     4321 acgagacgaa gagacagaca aggttcacat ccgtgcaacc atcatggtcg agcgcgatag
     4381 ccaaaaaggg attatcatcg gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc
     4441 ccgtcgtgat atcgaactca tgctaggaga caaggtcttc ctagaaacct gggtcaaggt
     4501 caagaaaaac tggcgcgata aaaagctaga tttggctgac tttggctata atgaaagaga
     4561 atactaagta gaggtaggct catgcctgct tcttgttttt acagaaggag gacttatgcc
     4621 tgaattacct gaggttgaaa ccgtttgtcg tggcttagaa aaattgatta tagggaagaa
     4681 gatttcgagt atagaaattc gctaccccaa gatgattaag acggatttgg aagagtttca
     4741 aagggaattg cctagtcaga ttatcgagtc aatgggacgt cgtggaaaat atttgctttt
     4801 ttatctgaca gacaaggtct tgatttccca tttgcggatg gagggcaagt atttttacta
     4861 tccagaccaa ggacctgaac gcaagcatgc ccatgttttc tttcattttg aagatggtgg
     4921 cacgcttgtt tatgaggatg ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct
     4981 tttagacgcc tactttattt ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga
     5041 tttacaggtc tttcaatctg cccttgccaa gtccaaaaag cctatcaaat cccatctcct
     5101 agaccagacc ttggtagctg gacttggcaa tatctatgtg gatgaggttc tctggcgagc
     5161 tcaggttcat ccagctagac cttcccagac tttgacagca gaagaagcga ctgccattca
     5221 tgaccagacc attgctgttt tgggccaggc tgttgaaaaa ggtggctcca ccattcggac
     5281 ttataccaat gcctttgggg aagatggaag catgcaggac tttcatcagg tctatgataa
     5341 gactggtcaa gaatgtgtac gctgtggtac catcattgag aaaattcaac taggcggacg
     5401 tggaacccac ttttgtccaa actgtcaaag gagggactga tgggaaaaat catcggaatc
     5461 actgggggaa ttgcctctgg taagtcaact gtgacaaatt ttctaagaca gcaaggcttt
     5521 caagtagtgg atgccgacgc agtcgtccac caactacaga aacctggtgg tcgtctgttt
     5581 gaggctctag tacagcactt tgggcaagaa atcattcttg aaaacggaga actcaatcgc
     5641 cctctcctag ctagtctcat cttttcaaat cctgaagagc aaaaatggtc taagcaaatt
     5701 caaggggaga ttatccgtga ggaactggct actttgagag aacagttggc tcagacagaa
     5761 gagattttct tcatggatat tcccctactt tttgagcagg actacagcga ttggtttgct
     5821 gagacttggt tggtctatgt ggaccgagat acccaagtag aacgcttaat gaaaagggac
     5881 cagttgtcca aggatgaagc tgagtctcgt ctggcagccc agtggccttt agaaaaaaag
     5941 aaagatttgg ccagccaggt tcttgataat aatggcaatc agaaccagct tcttaatcaa
     6001 gtgcatatcc ttcttgaggg aggtaggcaa gatgacagag attaactgga aggataatct
     6061 gcgcattgcc tggtttggta attttctgac aggagccagt atttctttgg ttgtaccttt
     6121 tatgcccatc ttcgtggaaa atctaggtgt agggagtgag caagtcgctt tttatgcagg
     6181 cttagcaatt tctgtctctg ctatttccgc ggcgctcttt tctcctattt ggggtattct
     6241 tgctgacaaa tacggccgaa aacccatgat gattcgggca ggtcttgcta tgactatcac
     6301 tatgggaggc ttggcctttg tcccaaatat ctattggtta atctttcttc gtttactaaa
     6361 cggtgtattt gcaggttttg ttcctaatgc aacggcactg atagccagtc aggttccaaa
     6421 ggagaaatca ggctctgcct taggtacttt gtctacaggc gtagttgcag gcactctaac
     6481 tggtcccttt attggtggct ttatcgcaga attatttggc attcgtacag ttttcttact
     6541 ggttggtagt tttctatttt tagctgctat tttgactatt tgctttatca aggaagattt
     6601 tcaaccagta gccaaggaaa aggctattcc aacaaaggaa ttatttacct cggttaaata
     6661 tccctatctt ttgctcaatc tctttttaac cagttttgtc atccaatttt cagctcaatc
     6721 gattggccct attttggctc tttatgtacg cgacttaggg cagacagaga atcttctttt
     6781 tgtctctggt ttgattgtgt ccagtatggg cttttccagc atgatgagtg caggagtcat
     6841 gggcaagcta ggtgacaagg tgggcaatca tcgtctcttg gttgtcgccc agttttattc
     6901 agtcatcatc tatctcctct gtgccaatgc ctctagcccc cttcaactag gactctatcg
     6961 tttcctcttt ggattgggaa ccggtgcctt gattcccggg gttaatgccc tactcagcaa
     7021 aatgactccc aaagccggca tttcgagggt ctttgccttc aatcaggtat tcttttatct
     7081 gggaggtgtt gttggtccca tggcaggttc tgcagtagca ggtcaatttg gctaccatgc
     7141 tgtcttttat gcgacgagcc tttgtgttgc ctttagttgt ctctttaacc tgattcaatt
     7201 tcgaacatta ttaaaagtaa aggaaatcta gtgcgagtaa aaattaatct caaatgctcc
     7261 tcttgtggca gtatcaatta cctaaccagt aaaaattcaa aaacccatcc agacaagatt
     7321 gaggttttaa agtattgtcc caaggaaaga aaagtaaccc tacatcttga atctaagtag
     7381 attttatggt aaaataatag ggattttaag gagtttgata tgtataacct attattaacc
     7441 attttattag tattatctgt tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac
     7501 caatccagca atgtatttga tgccagttca ggtgatttgt ttgaacgcag taaagctcgc
     7561 ggttttgaag ctgtaatgca gcgtttgaca gggattttag tctttttctg gctagccatt
     7621 gccttagcat tgacggtatt atcaagtaga taagaaaata atgggcagga ctaggtcttt
     7681 gcctcttttt atttttaaag gatgtttgag aaggttttac agtaaaagaa aattaaaaaa
     7741 tctagaaaga aaatatgaaa gatagaataa aagaatattt acaagacaag ggaaaggtga
     7801 ctgttaatga tttggctcag gctttgggaa aagacagttc caaggatttt cgtgagttga
     7861 ttaaaacctt gtccttaatg gaaagaaagc accaaattcg ttttgaagaa gatggtagtc
     7921 tgacattaga aattaagaaa aaacatgaga ttaccctcaa ggggattttt catgcccata
     7981 aaaatggctt tggctttgtt agtctggaag gcgaggagga cgaccttttt gtagggaaaa
     8041 atgatgtcaa ctatgctatt gctggtgata ccgtcgaggt agtgattaag aaagtcgctg
     8101 accgcaataa gggaacagca gcagaagcca aaattattga tatcctagaa cacagtttga
     8161 caacagttgt cgggcaaatc gttctggatc aggaaaaacc taagtatgct ggctatattc
     8221 gttcaaaaaa tcagaaaatc agtcaaccga tttatgttaa gaaaccagcc ctaaaattag
     8281 aaggaacaga agttctcaaa gtctttatcg ataaataccc aagcaagaaa catgatttct
     8341 ttgtcgcgag tgttctcgat gtggtgggac actcaacgga tgtcggaatt gatgttcttg
     8401 aggttttgga atcaatggac attgtatccg agtttccaga agctgttgtt aaggaagcag
     8461 aaagtgtgcc tgatgctccg tctcaaaagg atatggaagg tcgtctggat ctaagagatg
     8521 aaattacctt taccattgac ggtgcggatg ccaaggactt ggacgatgca gtgcatatca
     8581 aggctctgaa aaatggcaat ctggagcttg gggttcacat cgcagatgtt tcttattatg
     8641 tgaccgaggg gtctgccctt gacaaggaag cccttaaccg tgcgacttct gtttacgtga
     8701 cagaccgagt ggtgccaatg cttccagaac gactatcaaa tggcatctgc tctctcaatc
     8761 cccaagttga ccgcctgacc cagtctgcta ttatggagat tgataaacat ggtcgtgtgg
     8821 tcaactatac cattacacaa acagttatca agaccagttt tcgtatgacc tatagcgatg
     8881 tcaatgatat cctagctggc gatgaagaaa agagaaaaga atatcataaa attgtaccaa
     8941 gtatcgaact catggccaag cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag
     9001 ctctcaattt tgataccaat gaagcgaaga ttttagtgga taaacaaggt aagcctgttg
     9061 atatcgttct tcggcagcgt ggtattgccg agcggatgat tgagtctttt atgttgatgg
     9121 ctaatgaaac agttgccgaa catttcagca agttggattt gccttttatc tatcgaattc
     9181 acgaggagcc taaggctgaa aaggttcaga agtttattga ttatgcttcg agttttggct
     9241 tgcgcattta tgggactgcc agtgagatta gccaggaggc acttcaagac atcatgcgtg
     9301 ctgttgaggg agaaccttat gcagatgtat tgtccatgat gcttcttcgc tctatgcagc
     9361 aggctcgtta tttggagcac aatcacggcc actatggact agctgctgac tattatactc
     9421 actttaccag tccaattcgt cgttatccag accttcttgt tcaccgtatg attcgggatt
     9481 acggccgttc taaggaaata gcagagcatt ttgaacaagt gattccagag attgcgaccc
     9541 agtcttccaa ccgtgaacgt cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa
     9601 aggctgagta tatggaagaa tacgtgggtg aagagtatga tgcagttgta tcaagtattg
     9661 tcaaattcgg tctctttgtc gaattgccaa acacagttga aggcttgatt cacatcacta
     9721 atctacctga attttatcat ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag
     9781 gtatcacttt ccgagtgggt cagcagatcc gtatccgtgt tgaaagagcg gataaaatga
     9841 ctggagagat tgatttttca ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga
     9901 aacagtctag tcgtagtggc agagggcgtg attcaaatcg tcgttcggat aagaaggaag
     9961 acaagagaaa atcaggacgc tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga
    10021 aaaaaggaaa gaaacctttt tacaaggaag tagctaagaa aggagccaag catggcaaag
    10081 ggcgagggaa aggtcgtcgc acaaaataaa aaggcacgcc acgactatac aatcgtagat
    10141 acgctagagg cagggatggt cctgactgga actgaaatca agagtgtacg agctgctcga
    10201 attaatctca aggatggctt tgctcaagtg aaaaatggag aagtttggct gagcaatgtt
    10261 catatcgcgc cttacgaaga gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa
    10321 ctcctgctcc ataaaaggca aattcaaaaa ttggaacaag agaccaaagg gacaggaatg
    10381 accttagttc cccttaaggt ctatataaaa gatggctacg ctaagcttct tttaggactt
    10441 gccaaaggga agcatgacta tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga
    10501 gatatcgcgc gtgtgatgaa agctgttaat cagcgataaa aagaggaatt gaaaatggaa
    10561 aaattagttg cctataaacg catgcctttg tggaataaac aaacaatgcc tgaagctgtt
    10621 cagcaaaagc acaatacaaa agttgggact tgggggaaaa ttactgtctt gaagggagct
    10681 ctcaagttta ttgaattgac agaagaaggg gaagttctag ctgaacacct ctttgaagca
    10741 ggggcagaca atccaatggc ccaacctcaa gcctggcacc gagtggaagc tgccacagat
    10801 gatgtggaat ggtacttgga attttattgt aaacctgagg attattttgc taaaaaatac
    10861 aataccaatc ctgttcattc agaggtccta gaggccatgg agacagtgaa acaagggaaa
    10921 gctttggatt tgggttgtgg tcaggggcgt aattctcttt ttctagccca gcaagatttt
    10981 gatgtgacgg ctgtagatca aaatggacta gctcttgaaa tcttgcaaag cattgtggag
    11041 caggaagatt tggacatgcc tgttggcctt tacgatatca attcagctag cattgaacaa
    11101 gaatatgatt ttatcgtttc aacagttgtt ctcatgtttc tacaagcgga ccgcattcca
    11161 gctattattc aaaatatgca ggagaaaacc agtgttggtg gttacaacct tatcgtttgt
    11221 gccatggaca cggaggatta tccttgctcg gttaacttcc cattcacctt taaagaagga
    11281 gaactggcag actattacaa ggattgggaa ttggttaagt acaatgaaaa tccaggccat
    11341 ttgcatcgtc gcgatgagaa tggcaatcgt attcaactac gctttgcgac cttactagct
    11401 aagaaaatca agtaaacaca catgaagatt aggaattttc ctgatctttt ttctttttta
    11461 cgaatgatat agaaaaggag ggaattcatg tttgttgcga gagatgctag gggagaattg
    11521 gtaaatgtgt tagaggataa acttgagaag caagcataca cctgcccagc ttgtggaggc
    11581 cagctccatt tgcgtcaagg accaagtgta cggacgcatt ttgcccataa atccttaaaa
    11641 gactgtgatt ttttctttga aaatgaaagt ccagaacacc tggccaataa ggaatccctc
    11701 tatcactggt tgaaaaaaga gacaaaggtt caattagagt acccgctttc agaacttaaa
    11761 cagattgcgg atgtatttgt aaatggcaat ctagctctag aagttcagtg tagtcccttg
    11821 cctcagaaag tccttaaaga gcgaagtgag ggctatcgta gtcagggtta ccaagtactg
    11881 tggttgctgg gtcaaaaact gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt
    11941 ctttatttca gtcaaaacat gggcttttat gtttgggaat tagacaagga aaaacaagtt
    12001 ttaagactca aatacctgat ttaccaggat ctccgcggta aactccatta tcaaatcaag
    12061 gaattttcct atggtcaagg tagtttattg gaaatattgc gtcttcccta taagagacaa
    12121 aaaatatctc attttacagt ttctgaggac aaggacatct gtcgctatat ccagcaacaa
    12181 ctttattatc aaaatctctt ttggatgaaa gaacaagcag aagcctatca aaagggagaa
    12241 aatatcctga cttatggact gaaagaatgg tatccacaaa ttcgaccaat agtgggcaaa
    12301 tttttccaga ttgaacaaga cttgactagc tattatcagc acttttatac ctattaccaa
    12361 aaaaatcctc aaaatgattg gcaaaagctt tatccaccag ccttttatca gcaatatttc
    12421 ttgaaaaata tggtagaata gaaaggatgg aggaatctaa tggtattaca aagaaatgaa
    12481 ataaatgaaa aagatacatg ggatctatca acgatctacc caactgacca ggcttgggaa
    12541 gaagccttaa aagatttaac agaacaattg gagacagtag cccagtatga aggccatctc
    12601 ttggatagtg cggataacct actagaaatc actgaatttt ctcttgaaat ggaacgccag
    12661 atggagaagc tttacgttta tgctcatatg aagaatgacc aggatacacg tgaagctaag
    12721 tatcaagagt actatgccaa ggccatgaca ctctacagcc agttagacca agccttttca
    12781 ttctatgatc ctgaatttat ggagattagc gaaaagcagt atgctgactt tttagaagct
    12841 caaccaaagc tgcaggttta tcaacactat tttgacaagc tcttgcaagg caaggatcac
    12901 gttctttcac aacgtgaaga agaattattg gctggagctg gagaaatctt tggttcagca
    12961 agtgaaacct tcgctatctt ggacaatgcg gatattgtgt tcccttatgt cctagacgat
    13021 gatggtaaag aagttcagct atctcatggg acttacacac gtttgatgga gtctaaaaaa
    13081 cgtgaggttc gccgtggtgc ctatcaagct ctttatgcga cttacgaaca attccaacac
    13141 acctatgcca aaaccttgca aaccaatgtt aaggtgcaaa attaccgtgc taaagttcgt
    13201 aactacaaga gtgctcgtca tgcagccctc gcagcgaatt ttgttccaga aagtgtttat
    13261 gacaatttgg tagcagcagt tcgcaagcat ttgccactct tacatcgcta tcttgagctt
    13321 cgttcaaaaa tcttggggat ttcagatctc aagatgtacg atgtctacac accgctttca
    13381 tctgttgaat acaattttac ctaccaagaa gccttgaaaa aagcagaaga tgctttggca
    13441 gtcttgggtg aggattactt gagccgtgtc aaacgtgcct tcagcgagcg ttggattgat
    13501 gtttacgaaa atcaaggcaa gcgttcaggt gcctactctg gtggttctta cgataccaat
    13561 gcctttatgc ttctcaactg gcaggacaat ctggacaatc tctttactct tgttcatgaa
    13621 acaggtcaca gtatgcattc aagctatact cgtgaaactc agccttatgt ttacggagat
    13681 tactctatct ttttggctga gattgcctca actaccaatg aaaatatctt gacggagaaa
    13741 ttattggaag aagtggaaga cgacgcaaca cgctttgcta ttctcaataa cttcctagat
    13801 ggtttccgtg gaacagtttt ccgccaaact caatttgctg agtttgaaca cgccattcac
    13861 caagcagatc aaaatgggga ggtcttgaca agcgatttcc taaataaact ctacgcagac
    13921 ttgaaccaag agtattatgg tttgagtaag gaagacaatc ctgaaatcca atacgagtgg
    13981 gctcgcattc cacacttcta ctataactac tatgtatatc aatattcaac tggctttgcg
    14041 gccgcctcag ccttggctga aaaaattgtc catggtagtc aagaagaccg tgaccgctat
    14101 atcgactacc tcaaggcagg taagtcggac tatccactta atgtcatgag aaaagctggt
    14161 gttgatatgg agaaggaaga ctacctcaac gatgcctttg cagtctttga acgccgttta
    14221 aatgagtttg aagcccttgt tgaaaaatta ggattggcat aaaatggttg aatcgtatag
    14281 taagaatgct aaccataaca tgcgtcgtcc tgtcgtcaaa gaagaaattg tagacttgat
    14341 gcgtcagcgt caaaagcagg tcacaggttt cttgaaagaa ttggaagaat ttgcccgcaa
    14401 ggaaaatatt cctattattc cccatgaaac ggttgcttat ttccgttttc ttatggaaac
    14461 catgcagcct aaaaatattc tggaaattgg gacggctatc ggtttttcag ctctcttgat
    14521 ggctgaacat gcgccaaatg ctaagattac aactattgat cgtaatccag aaatgattgg
    14581 ttttgccaag gaaaattttg cccagtttga cagtcgcaag caaatcactc tcctagaggg
    14641 agatgcggtg gatgtcttat ctacactgac agagtcttat gatttcgtct ttatggattc
    14701 tgccaagtct aaatacatcg tctttctgcc agaaatcctc aaacatttgg aagttggtgg
    14761 tgtggttgtc ttggatgata tttttcaagg tggtgatgtt gccaaggata ttatggaagt
    14821 ccgtcgtggt cagcgaacca tttatcgagg ccttcaaaaa ttatttgatg caaccttaga
    14881 caatccagaa ctcaccgcaa cattagtgcc tttaggagat ggtattctca tgcttcgtaa
    14941 aaatgtagca gatgttcaac tgtctgaaag cgaatgattt tcagaaaaat ttaagaaaaa
    15001 atagtaaaat agatagagta acacttatct caaaggagta gacatgaaga aaaaattatt
    15061 ggcaggtgcc atcacactat tatcagtagc aactttagca gcttgttcga aagggtcaga
    15121 aggagcagac cttatcagca tgaaagggga tgtcatcaca gaacatcaat tttatgagca
    15181 agtgaaaaac aacccttcag cccaacaagt cttgttaaat atgaccatcc aaaaagtttt
    15241 tgaaaaacaa tatggctcag agcttgatga taaagaggtt gatgatacta ttgccgaaga
    15301 aaaaaaacaa tatggcgaaa actaccaacg tgtcttgtca caagcaggta tgactcttga
    15361 aacacgtaaa gctcaaattc gtacaagtaa attagttgag ttggcagtta agaaggtagc
    15421 agaagctgaa ttgacagatg aagcctataa gaaagccttt gatgagtaca ctccagatgt
    15481 aacggctcaa atcatccgtc ttaataatga agataaggcc aaagaagttc tcgaaaaagc
    15541 caaggcagaa ggtgctgatt ttgctcaatt agccaaagat aattcaactg atgaaaaaac
    15601 aaaagaaaat ggtggagaaa ttacctttga ttctgcttca acagaagtac ctgagcaagt
    15661 caaaaaagcc gctttcgctt tagatgtgga tggtgtttct gatgtgatta cagcaactgg
    15721 cacacaagcc tacagtagcc aatattacat tgtaaaactc actaagaaaa cagaaaaatc
    15781 atctaatatt gatgactaca aagaaaaatt aaaaactgtt atcttgactc aaaaacaaaa
    15841 tgattcaaca tttgttcaaa gcattatcgg aaaagaattg caagcagcca atatcaaggt
    15901 taaggaccaa gccttccaaa atatctttac ccaatatatc ggtggtggag attcaagctc
    15961 aagcagtagt acatcaaacg aatagtccaa atcaatgagt cagggaaaaa aactcgactt
    16021 caggaaaaaa tgaagcaaac attcccaaaa taaaacgcat agtacaaggt ttgtactgcc
    16081 cccaaaagtt agacaattaa tttatctgaa ggatttagtt ctgtattgca cagggctaag
    16141 tccttttagt tttaccttaa ttctcttatt gttgtaataa tcaata
//
LOCUS       DAVLZG010000050        16137 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLZG010000050 DAVLZG010000000
VERSION     DAVLZG010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.050"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     regulatory      73..161
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            376..1044
                     /locus_tag="VYO72_001575"
     CDS             376..1044
                     /locus_tag="VYO72_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1707916.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     gene            1287..2069
                     /gene="thiM"
                     /locus_tag="VYO72_001576"
     CDS             1287..2069
                     /gene="thiM"
                     /locus_tag="VYO72_001576"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1707917.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            2071..2700
                     /locus_tag="VYO72_001577"
     CDS             2071..2700
                     /locus_tag="VYO72_001577"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1707918.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      2909..2997
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3258..3818
                     /locus_tag="VYO72_001578"
     CDS             3258..3818
                     /locus_tag="VYO72_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1707919.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            3819..5204
                     /locus_tag="VYO72_001579"
     CDS             3819..5204
                     /locus_tag="VYO72_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707920.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            5206..5856
                     /locus_tag="VYO72_001580"
     CDS             5206..5856
                     /locus_tag="VYO72_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1707921.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFLPSIALNLLVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            5867..6625
                     /gene="tenA"
                     /locus_tag="VYO72_001581"
     CDS             5867..6625
                     /gene="tenA"
                     /locus_tag="VYO72_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1707922.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEEWKHEKAPTTSSQINHFIYDDCP"
     gene            6564..7088
                     /gene="thiW"
                     /locus_tag="VYO72_001582"
     CDS             6564..7088
                     /gene="thiW"
                     /locus_tag="VYO72_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1707923.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            7088..7891
                     /locus_tag="VYO72_001583"
     CDS             7088..7891
                     /locus_tag="VYO72_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1707924.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            7884..8516
                     /locus_tag="VYO72_001584"
     CDS             7884..8516
                     /locus_tag="VYO72_001584"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1707925.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKIETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8725..9516)
                     /gene="thiD"
                     /locus_tag="VYO72_001585"
     CDS             complement(8725..9516)
                     /gene="thiD"
                     /locus_tag="VYO72_001585"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1707926.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(9600..9698)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9882..10277
                     /locus_tag="VYO72_001586"
     CDS             9882..10277
                     /locus_tag="VYO72_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1707927.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVDKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            10288..10659
                     /locus_tag="VYO72_001587"
     CDS             10288..10659
                     /locus_tag="VYO72_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1707928.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKRSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            10669..12912
                     /locus_tag="VYO72_001588"
     CDS             10669..12912
                     /locus_tag="VYO72_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1707929.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKEIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNILGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            13119..14894
                     /gene="spxB"
                     /locus_tag="VYO72_001589"
     CDS             13119..14894
                     /gene="spxB"
                     /locus_tag="VYO72_001589"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1707930.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            15005..15352
                     /locus_tag="VYO72_001590"
     CDS             15005..15352
                     /locus_tag="VYO72_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1707931.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(15469..16137)
                     /locus_tag="VYO72_001591"
                     /pseudo
     CDS             complement(15469..16137)
                     /locus_tag="VYO72_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         4744 a         2960 c         3544 g         4889 t
ORIGIN      
        1 taaagatatt tttcggtcaa atatcttgct agggctttca ttttttgcta tactggttca
       61 gtaattaaat aatagagaca tttggggtgc tttaggctga gataataccc attgaacctg
      121 atacagttaa gactggcgaa gggaaatgtg aaacgttttt tcgtatggcg aaatgaacga
      181 tctaatcttg taagtcaact ctaattcttg attgtaattg gagttttttg tttatataaa
      241 ctggataggc ttgtttagtt agctctctgc aaatgctctc gatgtgcttt aaaaggatca
      301 agtggaatta cgattttgct tgatatttct tggtgtttta ttaattacta acaagtaaag
      361 agaggagaag taaatatgga aacacaagac tatgcatttc agccaggttt gactgttgga
      421 gaattattaa aaagcagtca gaaggattgg caggctgcaa tcaatcatcg ttttgttaag
      481 gaactttttg cggggacaat tgagaataag gtcttaaagg actatctgat tcaagattat
      541 cacttctttg atgccttctt atccatgctg ggtgcctgcg tagctcacgc agataaactt
      601 gaatccaagc ttcgttttgc caagcaacta ggctttcttg aagcagatga agatggttat
      661 ttccaaaagg cttttaaaga gttaaaagta gcagagaatg actatctaga agtgactttg
      721 caccctgtaa caaaagcctt tcaggatcta atgtattcgg cggtggcttc atcagactat
      781 gcccatcttt tggtcatgct ggtcattgca gaaggtctct atttagactg gggttctaaa
      841 gatttggctt tacctgaagt ctatattcat tcggaatgga tcaatctcca cagaggtcct
      901 ttctttgcag agtgggttca atttctggtt gacgaactca atcgtgtcga taaaaatcga
      961 gaagatttga cagaacttca gcaacgctgg aatcaagcag tcgctttaga attagctttt
     1021 tttgatattg gttacaatgt ctagagaagg ctcatgatat ttacaaattt gatgaggtaa
     1081 gactcttcga aaatctcttc aaaccacgtc agttctatcc acaacctcaa aacagtgttt
     1141 tgagcaacct gcggttagcc tcctagtttg ctctttgatt ttcattgagt ataaatcatt
     1201 caatgtaaat gaaaaaaatt cttaacgaaa gatagaaata aatcgaaatc agtagatcgt
     1261 ataaagtgaa aaggaaggat ttcaatatga caagtttaaa attattaaaa gaaaaagcac
     1321 cattggtcat ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag
     1381 cactgggcgc ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt
     1441 atgctggtgg tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc
     1501 aagctgctct gaaaattgca gagaaatata atgtcccagc agttttagat cctgtagcct
     1561 gtggagcagg agaatataga aaaaaagtag cagatgatct aatcaacaat tataaactag
     1621 cagcgattag aggaaatgct ggcgagattg cctctttagt aggaatagat gtggcatcta
     1681 aaggagtaga tagtgcgggc gtagataata ttgacgaaat tgctctagca gcaaatgaga
     1741 agttcaatat tccaatagta gtaacaggtg aagtggatgc cattgctgtt aatggagaag
     1801 tggtaacgat tcataatggt agtgctatga tgccgaaagt cattgggaca ggatgcttat
     1861 taggggcagt ggtagcaagc tttatcggac tagaaaaagg tcaagaattg aaatcattag
     1921 aaacagcaat gttggtttac aatatcgctg gagaaatggc agaaaaacgt ccaaatggac
     1981 atcttcctgg gacatttaaa gttgaattta taaatgcctt atacgagatt acagatgaag
     2041 atgtaaagga attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat
     2101 tttatttgtg gaacgactac ttgccaagga aaaaatctat atacagtcgt tgaggaagcc
     2161 ttaaaaggtg gtataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc
     2221 ttagaaaaac ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgtgccg
     2281 tttatcgtta atgatgatat cgatttggca atggaaattg acgctgatgg cgtacatgta
     2341 ggtcaagatg atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt
     2401 ctttctataa aaaacgagga agaatttcaa caatcaaaag ttgaatatgt agattatgtt
     2461 ggtgttggtc ctgtatttga tacccagtca aaggatgatg ctggtggtgc tataggttat
     2521 gaaggtcttg aattgatgag aaaactattg ccacaaatgc ctttagttgc aattggtggg
     2581 atacagacga aacatattaa agacattata aagaccaatg ttgacggcgt ttcaatcatt
     2641 tcggcaatat cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgagcaatag
     2701 atatctatcc ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga
     2761 ttcagcttga atggttaatt catcaaacag gtcatttgtt ttttgcaaaa gaaagatctg
     2821 ctgtctttgt gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt
     2881 gtgttataat aatcacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg
     2941 atacccattg aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg
     3001 tatgtcgaaa agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga
     3061 gttttttctt ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca
     3121 aatcaattag aaaattcaaa ttaatttcta gaaatatttt agcattcttg tgtactgttc
     3181 taaattcagt ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt
     3241 taaaaaaagg agtttttatg ttgaaaaaat ggcagttaaa agatgttatc ttgcttgctt
     3301 tcttgtctat cttttttggt ggggttttcg ttggttcagg atatgtgtat aatattctca
     3361 gtctactctt aacacctctt ggtttgcagg cctttgccaa tgaaatcctc ttcggtctct
     3421 ggtgtatggc tgcgcccatt gctgccatct ttgttccaag agtcggaagt gcaacgattg
     3481 gagaagtgct agctgcgctt gctgaagtcc tttatggtag ccaatttggt ctaggagctc
     3541 ttttgtctgg cttggttcaa ggtttgggaa gtgaatttgg ttttatcgta actaagaatc
     3601 gctatgaaag ttggctctct ctaactgcta atagtattgg gattacgctt gttagctttg
     3661 tctatgaata cattaagtta ggttactacg ccttttccct tccgtttgtc ctttccttac
     3721 ttgtggtacg ttttatttct gtttatttct tctgtaccat cttggttcgt gccattgtca
     3781 aactctatca tcagtttgca actggaggaa aagcatagat gggtctggaa ctacgagcga
     3841 ttcagtcccc aatcttctct gagccgtttg attttacttt tcatgcgcaa gcctttacct
     3901 tgttagttgg gagcagtggt tcaggaaaat ccagcctttt tcaagtcatt gcccaagtca
     3961 gttctcttcc ctatagtggt caagtcctga tagatgggag cgaggtcagt cagctttcta
     4021 tcatcgcacg tgtccagaag gttggcattc tcttgcaaaa tcccaatcat caatttacca
     4081 tggagaactt gtttgaggag ttgattttca ccttggagaa tatcggctat caccttcagg
     4141 aaattgattc taaaatagca gaggttgtcc agcaatgtcg ttgcgaggca atcttacacc
     4201 gtcccattca tcacctatca ggtggggaaa agcaaaaagc agcgctggct gtcctctttg
     4261 ccatgaatcc tagggtctat ctcttggatg agcccttcgc ttccattgac cgcaagagta
     4321 gaatcgagat attggagatt ctaaaagagt tggctcttga tgggaagaca gtcattttgt
     4381 gcgaccatga tttatctgac tataaagcct atatcgacca tatggttgag ctaagagacg
     4441 gaaaactaag ggaagtgttt caaatccctt cctatgagat gacacaggtt gcttcaaagg
     4501 aagttgctgc tagcccggaa ttattccata tgaaccgtgt gactggtgag cttggaaatc
     4561 gctccctctt ttcgattgct gatttcacat tctatcaagg gatttcctgt atcctgggtg
     4621 acaatggtgt cgggaaatca accctctttc gctctattct tcaatttcaa aagtataagg
     4681 ggcgcattac ttggaagggt tcggtcctga aaaagaaaaa gagtttgtat cgtgatctga
     4741 ctggtgttgt tcaggaagct gagaagcagt ttatccgagt cagtctgcga gaggagcttc
     4801 aattagatgg acctgattct gaaagaaatc agcggatttt tcaagcttta cgatattttg
     4861 atttggagca ggcagtcgat aagagtccct atcaattaag tggtggtcag caaaaaattc
     4921 ttcagctctt gaccatcttg accagtaagg cttccgtgat cttgctagat gaaccttttg
     4981 caggtttgga tgatagagcc tgccattatt tttgcaagtg gattgtggag gagaggaatc
     5041 aaggaagaag ttttctgctc attagtcatc gtttagaccc tttgatttct gtggttgatt
     5101 attggattga gatgactagt cagggtcttc ggcatgtgaa agaagtgacc attaccaaac
     5161 cacttacatc tcagagtagc aatacccaag gggaggtgag atagtatggt caaagtagca
     5221 acccagacac cgattatcag tctcttcttg ctgattttat ccttggaaac atctttcctt
     5281 ccttcgattg ctctgaatct tttggtagtc gcattttgta ttctctttat gctctattac
     5341 cgtcgattta aaatgttagc ttggatgatc atacttgcca ttttaccatc ttttgccaac
     5401 tactgggcag ttcagttaca cggagatgct tcacaggcag tcatgcttgg aacgagggcc
     5461 tttgtgacag tttgtatcgg ccttgtcttt gtttcctcta tttcactaaa agagcttctc
     5521 ttgtacttgg ctcaaaaggg gctatcacgc tcttggtcct atgccttgat tgtggtattc
     5581 aattcttttc ctctcattca gcaagaaatc aagtccctca aagaagcttg cctattacgt
     5641 ggtcaagaac tacatttttg gtcgcccttg atttacagta aggttctgat gacagtcttt
     5701 aggtggcgcc atctttacct gagagctcta tctgctcacg gatatgacga acatgcacag
     5761 ttgaagaata gctatcggac tttttatatt cctaaaaaaa caaaattaat ctacctgctt
     5821 ttctttttat tgcttcaaac cagtctattt ttataaagga gttattatgg aatttacaga
     5881 tattgcgatg gaattatcca agaaagcttg gcaggcttcc tttcatcatc cctttatttt
     5941 acaattacaa gaggggaatt tagaacctgc cattttccgc tattacctga ttcaggatgc
     6001 ctactatctg aaggccttct cagaaatcta tcatcttttg gctgataaga cttcaaacca
     6061 agagatgaaa agactcttga aacaaaatgc tcagggttta gtggagggtg agttatttat
     6121 tcgccaacaa tttttcaagg aaatggaaat cagcgaccag gaaatggagc aacatccaat
     6181 cgctccaacc tgttatcatt acatttctca tatttatagg caatttgcag aaccgaactt
     6241 agccatcgct tttgcaagct tgcttccttg tccttggtta taccatgata taggcaaatc
     6301 acttaatctt aaaccatcac caaatcctct ctatcaacaa tggattgaaa cttatattac
     6361 ggatgagtta gagcaacaga tcagagagga gggagcactg gtcaatcagc tctatcgaga
     6421 aagtgacgag acagacaagc aaaaaatgct agatgccttc cacatcagtg ttcatatgga
     6481 agccaagttt tgggaaatgg cctaccaaca ccagacatgg aagagcgatt tacagtcttt
     6541 agaaaaagga gaagaatgga agcatgagaa agcaccaact acaagttcac aaattaacca
     6601 ttttatctat gatgattgcc cttgatgtag tccttacacc tatctttcgg attgagggaa
     6661 tggcaccgat gtccagtgta gtcaatattc tagcgggaat catgatggga cctgtttatg
     6721 ccttggctat ggctacagtg acagccttta tccgtatgac gactcaaggg attccgcctt
     6781 tagctctcac aggagcgact tttggagccc ttctagcagg tctcttttat aagtacggtc
     6841 gaaaatttta cttttctgcc ttgggagaaa ttgtgggaac aggtattatt ggttctattg
     6901 tttcctatcc tgttatggta ctctttacag gatcagctgc taagcttagc tggtttatct
     6961 acacgcctcg atttttcgga gcaaccttga ttggtacagc gatttccttt attgcctttc
     7021 gatttttaat caagcaggaa ttctttaaaa aagtgcaggg atatttcttt agtgaaagga
     7081 tagactgatg caggaattta caaatccctt tcctataggc tctagttccc tcattcactg
     7141 cattaccaat gagatttctt gtgagatgct ggcaaatggg attttggctc tgggatgcaa
     7201 acctgtcatg gcagatgatc cccgtgaggt tcttgatttt actaagcaaa gtcaggctct
     7261 cttcatcaat ttggggcatt tgtcagctga gaaggagaaa gcaatccgta tagcagcttc
     7321 ttatgcagct caagtttgtc tcccaatggt agtagatgcg gttggcgtaa cgacttcatc
     7381 cattcgtaag agcttagtta aagacctttt agactataga cctacggtcc ttaaaggaaa
     7441 catgtcagaa attcgaagtc ttgttggatt aaagcaccac ggcgttgggg tcgatgcgag
     7501 tgctaaagat caagaaacgg aggatttgct tcaagtcttg aaagactggt gtcagaccta
     7561 tcctggtatg tcattcttag ttactggccc caaggacctc atcgtttcgg agaatcaagt
     7621 tgctgtactg ggaaatggct gtgcagaatt agactggata acagggacag gagatttggt
     7681 tggagcctta acagccgttt ttctcagcca aggaaagact ggttttgaag cttcttgctt
     7741 agcagtctct tatcttaata tcgctgctga gaaaatagtt gttcaaggaa tgggattgga
     7801 agaatttcgt taccaagtac tcaatcagct ttcgctccta agaagagatg aaaattggct
     7861 agataccatc aaaggagagg tttatgaata gagaagcact tagactatat ctggtaacca
     7921 atcgctatca agattccgtg gaaagctttc ttgcaaaaat tgagacggcc tgccgttcag
     7981 gggttaccat agtccaattg cgagaaaaaa atctcacaac caatcaatat tatcaactgg
     8041 caaaacaagt caaggaaata acagatgctt atcaggtacc cttgataatc gatgatcggt
     8101 tggatgtttg tcttgcggtt gatgctgctg gtctgcatat tggagatgac gaactcccag
     8161 tttcggttgc ccgacaagtc ttgggtcctg aaaaaatcct cggtgtcacc gctaaaacgg
     8221 ttaaaagagc tctggaagcg gagaaatcag gtgcagatta cttggggaca ggagccattt
     8281 ttccgacaac caccaaggaa aatgcaccca tcaccctgat ttcaaccttg aaaacaattt
     8341 gccaaacggt tgccattcca atagttgcta ttggcggctt gacttcggag aatattgatc
     8401 agcttatggg cactggcata gctggtgtag ctgttgtacg tgatttgatg caagcagaag
     8461 atattgaggc aaaaacgcaa gcctttttaa caaagttgca tgacattctt tcctaattaa
     8521 tactcaatga aaatcaaaga gtaaactaga aagctagtcg caggttgctc aaagtactgc
     8581 cttgaggttt tagataagac tgacgaagtc agctcaaaac agtgttttga agttgcagat
     8641 ggaagctgac gtagtttgaa gagattttcg aagagtataa aaactctcta attcccttaa
     8701 agtgggaact agagagtttt tttcttaatc tttaaaagtt gtatggttga ctggaccaga
     8761 accatgaccg agttgagggg catcttgaat agcttttgtg ataaaggcct tggccttatc
     8821 aactgcctgg taaagactct tgcccttggc tagttcagca gtaatcactg cagcaaaggt
     8881 acatccagta ccatgggtgt gacaggtttg aattcgtggg ctttcccaga caaattgttc
     8941 attcttggta aagaggaaat ctttagcacc acctttgaga tgtccgcctt tgataaccac
     9001 agactgagga ccaaattctt ttaaaatcag gcgaccagca cgctgcatgt cttcggggtc
     9061 atggattgaa aaaccaacaa tctcttctgc ttcaggaaga tttggcgtaa taatagttgc
     9121 tagaggtagt aagtttgttt tgagatagtc tctagcattt gagtcaatca aggcatctcc
     9181 acttgtagca accataacag gatcaaggac atagggacaa tccagttttt taagataggg
     9241 ttggatgatt tccatgattt cagtagtagc caacattcca gtttttacag cctgaggtgg
     9301 aatatcagaa aagacactct ccaattgggc tttcaacatt tgaggagaaa cgtgctcgat
     9361 tagctgaaca cctctggtat tttgagcgac aagactggtt acaacagcca ttccatagac
     9421 atctctcgct tggaatgact ttaaatctgc cataatgcca gcaccaccac tagggtcagt
     9481 ccctgcaatg gtcaaagcaa cgggtaaata agtcatctaa aacctcccaa ccaactgaag
     9541 tttgtattct taagaacaag ctagtctgtt ttagaaaggc aatagaagac tgctagtccc
     9601 cattatcatt tccacttcca tcagctagca ttacctagat tgagtcagag ggatctagca
     9661 gtcgttaatc tcagctttac gcacccctag tggttgtttt cttttttctt tagtatagca
     9721 tatttttatt gtttatatag taatatttga ctgcaaatcg tttttcaaat gattaaaatt
     9781 ctatttttcg aagaaaatat tatttctata attgacaaat gtagatttta agagtatact
     9841 gataagtgta attgacaaat gtagattttg gaggtatggt aatgcagatt tcagatgcag
     9901 aatggcaggt catgaagatt atttggatgc agggggagca gaccagtaca gatttgatta
     9961 gggttttggc agagcggttt gactggtcca agtccacggt tcagacactt ttggctcgtc
    10021 tggttgataa agagtgtttg actcggaaaa aagaaggcaa gtcctttgtt tattcagccc
    10081 ttttaactct agaccaaagt cgggatttac ttgtccaaga tatcaaagac aaggtttgtt
    10141 cccgtaggat taggaatttg ttggctgact tgattgtaga atgtgaattt actcagactg
    10201 acttggaaga cttggaagct gtgatttcag agaagaaatc aagtgctgta acagaagtaa
    10261 gatgtaattg tatgtaaagg agacgtcatg ttaaatagta ttgtaaccat tatttgtatt
    10321 gctcttatcg cgtttatctt gttttggttt ttcaaaaagc ctgaaaaatc tggacaaaaa
    10381 gcccagcaaa aaaacggata ccaagagatt cgagtggaag tcatgggagg ctatactcct
    10441 gagttgattg tcctcaagag atcagtgcca gcccgcattg tctttgaccg caaggatcct
    10501 tcaccatgtc tggatcaaat tgtttttcca gattttggtg tacatgcgaa cctgccaatg
    10561 ggggaagagt atgtagtgga aatcacgcct gagcaggctg gagagtttgg ctttgcttgt
    10621 ggtatgaaca tgatgcacgg caagatgatt gtagagtagg tggagactat gacagaaatt
    10681 gtgaaagcaa gcttagaaaa tggcattcaa aaaatccgta tccgagctga aaaaggctat
    10741 catccagccc atatccagct tcaaaaggaa attccagctg agattacctt tcatcgtgct
    10801 actccttcaa actgttataa ggaaattctg tttgaagaag aaggtatctt ggaaccaatc
    10861 ggcgtagatg aggagaaagt cattcgtttt acacctcaag aattagggcg acatgaattt
    10921 tcttgtggca tgaagatgca aaagggaagc tatatagtcg ttgagaagac tcgaaaatct
    10981 ctatctctcc tgcaacgttt ttggattact agtatcttta ctgtgcctct tgtgattctc
    11041 atgattggga tgttgacagg tagcattagt catcaagtca tgcattgggg aacctttcta
    11101 gcaacaacgc ctattatgtt agttgcaggt aagccatata tccagagtgc ttgggccagt
    11161 tttaaaaagc acaatgccaa catggatacc ttggttgcgc tgggaactct agtggcttat
    11221 ttctatagcc tagttgctct ctttgctggt ctccctgttt acttcgaaag tgctggattt
    11281 atcctctttt tcgttctttt gggagcagtt tttgaggaaa aaatgagaaa aaatacgtcc
    11341 caagctgtgg agaaattact ggacttgcaa gctaaaaccg cagaagtctt gagtgatgat
    11401 agttatgtcc aagttccttt ggaacaagtc aaggtaggcg acctgattcg agtgcgtccc
    11461 ggtgaaaaga ttgctgttga tggtgtcgta gtagaaggtg tctctagtat tgacgaatcc
    11521 atggtgacag gtgagagtct gcctgtggac aagacagttg gagatactgt cattggctca
    11581 accatcaatc atagtggaac gcttgtcttt agagcagaaa aagttggctc agagactgtt
    11641 ttggctcaga ttgtggattt tgtgaagaaa gctcagacaa gtcgtgcgcc gattcaggac
    11701 ttgacggata agatttcagg gatttttgtc ccagtagttg tcattttagg aatcatgacc
    11761 ttttgggttt ggttcgtctt gctcagggat agtgtggttg tgcttggagc tagctttgtg
    11821 tcctctcttc tctacggagt ggcggttttg attatcgcct gtccttgtgc cttgggactt
    11881 gcaacaccga cagcccttat ggtggggaca ggacgtagtg ccaagatggg ggttctcctc
    11941 aaaaatggaa ctgtcttaca ggaaatccag aaagttcaaa cccttgtctt tgataagacc
    12001 gggactttga cggaagggaa acctgtggta acagatgtca tcggcgacga agtagaagtg
    12061 tttgggttgg cagcctcctt ggaagatgct tctcaacacc cactggctga ggctatcgtt
    12121 aagcgagcga gtgaagctgg acttgagttt caaactgttg aaaattttca gtccttgcac
    12181 gggaaaggtg tttcagggcg aatcaatgga aaacaagttt tacttggaaa tgctaaaatg
    12241 ctggatggca tggatatttc taatacttat caagataaac tagaagaact agaaaaagaa
    12301 gctaagacag ttgtgttctt agctgttgac aatgaaatca aaggcttgct tgctttgcaa
    12361 gatattccta aggaaaatgc taagctagcc atcagtcagc taaaaaaacg tggtctccga
    12421 acagtcatgc tgacaggaga caatgctggt gtggcgcgtg ctattgcaga tcaaatcgga
    12481 attgaagagg tcattgcagg cgtcttgcca gaagaaaaag cccatgaaat ccataaactg
    12541 caacagtcag ggaaagtagc ctttgttggg gacggtatca atgacgctcc tgcccttagt
    12601 gtagcagatg tgggaattgc tatgggtgct ggaacagata tcgccatcga gtcagcagat
    12661 ttggtgttga caaccaataa tattttagga gtggttcgtg cctttgatat gagtaagaaa
    12721 acctttcatc gaattctact caatcttttc tgggctttta tctacaatgt tgtcggaatt
    12781 ccgattgcag caggagtctt ttcaggtgtt ggactggctc tcaacccaga attggcaggt
    12841 ctagccatgg cctttagttc tgtatctgtt ctgaccagtt cccttctgtt aaattttagt
    12901 aaaatagact aaaagtaatg actagatttc tttgttataa aacagaaatg acaacacttt
    12961 caaaactgta ttagaataga gaatagagag ttttgagcag atttttagaa aagtcagcat
    13021 aaatatgata cagtggaata gtaaaaattt ggagaacgtt tccaattcta tgtaatcgta
    13081 ttctccaagt ctaaaaaaat tgaaggagag ttatcattat gactcaaggg aaaattactg
    13141 catctgcagc aatgcttaac gtattgaaaa catggggcgt agatacaatc tacggtatcc
    13201 catcaggaac actcagctca ttgatggatg ctttggctga agacaaagat atccgtttct
    13261 tacaagttcg ccacgaagag acaggtgctc ttgcagcggt tatgcaagct aaattcggcg
    13321 gctcaatcgg ggttgcagtt ggttcaggtg gtccaggtgc gactcacttg attaacggtg
    13381 tttacgatgc agctatggat aacactccat tcctagcgat ccttggatca cgtccagtta
    13441 acgaattgaa catggatgct ttccaagagc ttaatcaaaa cccaatgtac aacggtatcg
    13501 ctgtttacaa caaacgtgta gcttacgctg agcaattgcc aaaagtaatt gacgaagcct
    13561 gccgtgctgc agtttctaaa aaaggtccag ctgttgttga aattccagta aacttcggtt
    13621 tccaagaaat cgatgaaaac tcatactacg gttcaggttc atacgaacgc tcgttcatcg
    13681 ctcctgcttt gaacgaagtt gaaatcgaca aagctgttga aatcttgaac aatgctgaac
    13741 gcccagttat ctatgctgga tttggtggtg ttaaagctgg tgaagtgatt actgaattgt
    13801 cacgtaaaat caaagcacca atcatcacaa ctggtaaaaa ctttgaagct ttcgaatgga
    13861 actatgaagg tttgacaggt tctgcttacc gtgttggttg gaaaccagcc aacgaagtgg
    13921 tctttgaagc agacacagtt cttttccttg gttcaaactt cccattcgct gaagtttacg
    13981 aagcattcaa gaacactgaa aaatttatcc aagtcgatat cgacccttac aaacttggta
    14041 aacgtcatgc tcttgacgct tcaatccttg gtgatgctgg tcaagcagct aaagctatcc
    14101 ttgacaaagt aaacccagtt gaatcaactc catggtggcg tgcaaacgtt aagaacaacc
    14161 aaaactggcg tgattacatg aacaaactcg aaggtaaaac tgagggtgaa ttgcaattgt
    14221 atcaagttta caatgcaatc aacaaacatg ctgatcaaga cgctatctac tcaatcgacg
    14281 taggtaacac tactcaaaca tctactcgtc accttcacat gacacctaag aacatgtggc
    14341 gtacatctcc actctttgcg acaatgggta ttgcccttcc tggtggtatc gctgctaaga
    14401 aagacaatcc agatcgccaa gtatggaaca tcatgggtga cggagcattc aacatgtgct
    14461 acccagacgt tatcacaaac gttcaatacg accttccagt tatcaacctt gtcttctcaa
    14521 atgctgagta cggcttcatc aagaacaaat acgaagatac aaacaaacac ttgtttggtg
    14581 tagacttcac aaacgctgac tacgctaaaa ttgcggaagc tcaaggagct gttggattca
    14641 cagttgaccg tatcgaagac atcgatgcag ttgttgcaga agctgttaaa ttgaacaaag
    14701 aaggtaaaac tgttgtcatc gatgctcgca tcactcaaca ccgtccactt ccagtagaag
    14761 tacttgaatt ggatccaaaa cttcactcag aagaagctat caaagccttc aaggaaaaat
    14821 acgaagcaga agaactcgta ccattccgtc tcttcttgga agaagaagga ttgcaatcac
    14881 gcgcaattaa ataattcctc tcgtcgaaaa tcaaatatga aacttgtaga ctttattctt
    14941 tgattttcat agagcagaac tttaaaagat cggagcaatc cggtcttttt atggaggaga
    15001 gtaaatgaat ttaaatcaat tagatattat cgtttcaaat gttccccaag tctgtgctga
    15061 cttggagcat atcttggata aaaaggcaga ttatgctgat gatggttttg ctcagtttac
    15121 gattggtagt cactgcctta tgttgtcaca aaatcatttg gttcctttgg aaaactttca
    15181 gtcaggaatc attattcata tcgaggttga ggatgtagac cagaactaca aacggttgaa
    15241 cgagcttggt ataaaggttt tacacggacc aactgtaacc gattggggaa cagagtcctt
    15301 attagttcaa ggacctgctg gtctagtgct tgatttttat cgtatgaaat aggtcgcgta
    15361 gtcatttgac gttaacctta gctattttta aaatagaaat tgagaatatg aactattgaa
    15421 agatcggagc aatccggtct ttttatataa agaaattgca tataatactc atctgctttc
    15481 aaaaagcatt ctagtccatc tccgattaac gatggacttt atcacctcct tctccaatcc
    15541 ttgtatgaca tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt
    15601 aaatccacgt ttacgaatct ctttccacac ttgttcaatg gggttcatct ctggtgtgta
    15661 tggaggaata aatgcaaagc caatattagt cggaatcttt aaggtacttg atttatgcca
    15721 tatagcattg tccataacga gtaaaaaata atcatatgga taagcttgtg aaagctcttc
    15781 taaaaagacg ttcatccact cagtattaca tccaccagct cttaagaaaa atgattcgcc
    15841 tgtataggca tcaacagctc cataacaata gcgaaattct cgtatatagt gactatggat
    15901 atgtggacct actcctattg gagaccaaca agatcccagt ttactgattc taccgaaacc
    15961 agcctcatct tggtacatca agtgaacctt acgaaaacgt ctactggttt taaatcgctt
    16021 tcttttcttc ttgaattgag attttatttt tagacgcgac aatggtttga gcgtctgctt
    16081 tcttaggatg ttctggacgt ggcgtaatat ttcgccaacc atggcgcttc aacagtt
//
LOCUS       DAVLZG010000051        14734 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLZG010000051 DAVLZG010000000
VERSION     DAVLZG010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.051"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            158..850
                     /locus_tag="VYO72_001592"
     CDS             158..850
                     /locus_tag="VYO72_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1707932.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(953..2598)
                     /locus_tag="VYO72_001593"
                     /pseudo
     CDS             complement(953..2598)
                     /locus_tag="VYO72_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(2588..3679)
                     /locus_tag="VYO72_001594"
     CDS             complement(2588..3679)
                     /locus_tag="VYO72_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707933.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(3692..4813)
                     /locus_tag="VYO72_001595"
                     /pseudo
     CDS             complement(3692..4813)
                     /locus_tag="VYO72_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(5031..5228)
                     /locus_tag="VYO72_001596"
     CDS             complement(5031..5228)
                     /locus_tag="VYO72_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1707934.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(5303..6079)
                     /locus_tag="VYO72_001597"
     CDS             complement(5303..6079)
                     /locus_tag="VYO72_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1707935.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            6201..6947
                     /locus_tag="VYO72_001598"
     CDS             6201..6947
                     /locus_tag="VYO72_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1707936.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            6960..7940
                     /locus_tag="VYO72_001599"
     CDS             6960..7940
                     /locus_tag="VYO72_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1707937.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            8135..8455
                     /locus_tag="VYO72_001600"
     CDS             8135..8455
                     /locus_tag="VYO72_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1707938.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            8501..8809
                     /locus_tag="VYO72_001601"
     CDS             8501..8809
                     /locus_tag="VYO72_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1707939.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            8826..10124
                     /locus_tag="VYO72_001602"
     CDS             8826..10124
                     /locus_tag="VYO72_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1707940.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            10275..12713
                     /locus_tag="VYO72_001603"
     CDS             10275..12713
                     /locus_tag="VYO72_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1707941.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPVTTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            12732..13400
                     /locus_tag="VYO72_001604"
     CDS             12732..13400
                     /locus_tag="VYO72_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1707942.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            13418..14506
                     /locus_tag="VYO72_001605"
     CDS             13418..14506
                     /locus_tag="VYO72_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1707943.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTIKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         4731 a         2217 c         3009 g         4777 t
ORIGIN      
        1 cagataacac tgaattagtt tgaatttgat tttcatctaa tatctttatt taatgaactc
       61 ctaaactttt tcataataat ctccttcaaa agtcgcctgt atgggtggct tttattttat
      121 cattcatgat ataatagaag caaacggagg acggaaaatg gtaaaagtac gattgtattt
      181 ggtacgtcat ggcaagacca tgtttaacac gattggtcgc gcgcaaggtt ggagcgatac
      241 tcccttaact gctgaaggtg aacgagggat tcaagagtta ggaatcggtt tgcgagaatc
      301 tgatctacag tttgagcgcg cttattcgag tgattctggt cgtaccattc agaccatggg
      361 aattatcctt gaagaacttg gcttgcaggg gaaaatccct tatcgcatgg acaagcgtat
      421 cagagaatgg tgtttcggta gttttgatgg agcctatgat ggcgatcttt tcatgggcat
      481 tattcctcgt atctttaatg tggaccacgt tcaccaattg tcttatgctg aactggctga
      541 gggcttggta gaggtcgata cagctggttg ggctgaaggc tgggaaaaac tcagtggccg
      601 aatcaaggaa ggctttgaaa tgattgcaaa agaaatggaa gatcaaggtg gaggtaacgc
      661 ccttgttgtc agccatggaa tgactattgg aaccattgtt tatctgatta atggcatgca
      721 tccgcatggt ctagataatg gtagcgtgac gattcttgaa tatgaggacg gtcagtttag
      781 ggttgaagtt gtcggtgacc gtagttaccg agagctagga cgtgagaaga tggaagaagg
      841 ctctatttaa tcagtctaga cttgcttgcc atgagctagg gatttgataa gaatatcaag
      901 ataagaaaaa acagccgagg gtactccttt cggctgtttt tgatgtggaa aactaaagtg
      961 taatgctatt gcttttagag attttcataa acaagagcaa ggaacctact gttagaacag
     1021 tcaggatagt tgacaaggct gcggctacac cgtaatttcc tctgagaacc tctgtataaa
     1081 tagctacagt cattgttctt gttttgacat tgtagaggag gatagaagta gagagttttg
     1141 aaatcattgt gacccaagat aagatggctc cagaaatgat accagatagc atcattggag
     1201 ttgtaatctt agcaaaggta ttgagacgac tacttcctaa gctttcagca gcttcttcaa
     1261 tacttggtgc tatttgttgt aagctagcaa cagatgagcg aatagtataa ggtaatcttc
     1321 tgacagatag agacataatc aagatgaaag cagtccctgt aatcataaga aatccacttc
     1381 caaatagacc agtattgaag gaagaaatga aggcaatccc tagaacggtt cctggtacaa
     1441 tataaggtac catactgagg ctgtcaatta agtttgtaaa caaattccgt tttctaacgg
     1501 ctaggtagga gataaatgtc gcaaatagaa caactagaac taaggcaatc aaagggatac
     1561 gaatggtatt gaaaatagca gatcccatac gatggaaagc taccttgtaa ctgtttggag
     1621 aataaccttt aacagatacc atacctgatg tttttaggaa agaggtataa attaagtaga
     1681 tttgaggtaa aacagagata aagataattc cgtagactgt tgcataaatg gcagctattt
     1741 ttccttttgt agttttttta ggctcaattg gatggagcag attcatgctg aaactgtagc
     1801 ggtttgcaat gtgtttttgg ataaggaaaa tcgccaaggc aatgataatc gccataattg
     1861 caaaagcaga atttcctcca acctcgctaa taaattgggt ataaatcagg acagggaaag
     1921 tccgatatcc ttcgccaatc aacataggcg ttccaaagtc tgagaatgct ctcataaata
     1981 caagcaagga actgctagta aggttggaac taggagaggt aaaacaaccg ttacgatacg
     2041 cttaaatccg aaggacccca tgctttcagc tgcttcaagt agagaattgt caatactgtt
     2101 cattgttcca gcaacatata gaaataccag tgggaatagt tgcagtgtaa agacaagtac
     2161 aattcctttg aatccataaa tatcgatagc tggaagatga agggcatttg tcaaaaattt
     2221 agtgatgacc ccatttcgtc ctagcaagag aacccaggag taggctccta cgaaaggagc
     2281 tgacatggaa gcaatgataa tcaatatttg tagaaatttc tcccccttga agtcatacat
     2341 agagaagaga taagctaata gggttcctac aactaaggaa gtgacagtag cggtaatgga
     2401 aaccttgaaa ctgttgacta gtgtctcaga gtagtagact ttactaaaga aagtgacaaa
     2461 attagctagt gagaattgtc cttcatgtat aagtgcttac ttgagcacgg taacgatagg
     2521 ataaacgaga aagacaagat aggtaagaaa gatgaagaaa gaggaggctg tccaaatatt
     2581 tagtttttta cgttccatgg ttgactcctt ttatcaggtt ttgggaacca tctgcagaaa
     2641 agatgtttaa tttttgcgta ttgattcgta gacgaatacg attgcctttt tgtagatctt
     2701 cttcaaaagt tgattcttca ctaacttgaa tttttgaggc aaaacctgtc tcaatgaaat
     2761 actccgtatt tagtccaaga tagacgctat cgctaatagt tccttcaata tctccagatt
     2821 catctttgat aaactcttcg ggacgaatgc ttacatgaat agcttgctcc tcaacctgat
     2881 caagagctag cattcgaagg gcatagccat ctgaaaagac gatataagcg ccgtcgctcc
     2941 gtttttcaag attggcaggg ataatatttg tgcgtccgat aaaggttgcc acaaactcat
     3001 tagctggttt atgatagagt tcttttggtc ggccgatttg ttggatcacc ccatctttca
     3061 taacagcaat ttggtctgaa atagccatgg cttcttcttg gtcgtgggtt acataaacag
     3121 ttgtaattcc cacttcgtgt tggatttctc ggatggcttg acgcatatcc aagcgaagtt
     3181 tggcctccag attactaagt ggctcgtcca tgaggagaac acttagatta accgctaagg
     3241 cgcatgccaa ggtgacacgt tgttgttgtc caccactgag tttatcgggc tttcgatccg
     3301 catattgagc aatttgcatg agttcaagat acttgttggt ctgttgaatc aattcttctt
     3361 ttggaacctt cttttgcata agaccaaaag caacgttgtc tcggacagtc aaatgtggga
     3421 aaatagcgta gttttggaaa accatcccga tattgcgttt gctgggttcc atattattga
     3481 tttttgtatc atcgaagtaa aattctccat ctttgatact gttgaaacct gcaatcatac
     3541 gaagaagggt cgttttccca catcctgaag ctccaagaag ggtaaagaga cttccttttg
     3601 gaattgtaat gttcaaattc tcaataacag agacatcgtg gtagattttt ttggcgttaa
     3661 taatttcgat ctcactcata gtgaacctct tttactgttt agattggata tctgtaaaga
     3721 cttcgttgta tttcttaacg atatctgatt tattcttgat gacataatca taatcttcag
     3781 tgagtgtttt gattttgtca attggtttca tgttttcgct tgttttagca tttttacgaa
     3841 caggacggtt agtagtggtt gtaccaagtg tatcttgtac ttcttgagag ataataaaat
     3901 cgataaattt cttggcattt tccatatttt tagatttttt aacgatagca gcactagcag
     3961 gtaggaagac ggttccttct tttggataga ctaccttaat gttagctccg tcatttaaga
     4021 gtttaactgc tggatcttca taagagagac caacagtcat ttctccatca gcgactgctt
     4081 tatagacacc agatgaactt aaaccgattt tatagtatat tgaaactaga atagtacaca
     4141 tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgattaattt gtcctgttct
     4201 tatttcattt tactatacca tcaataagtg tgaaaagatc ttttacataa gaccaagcct
     4261 tatcatcttt gtaaccacct tgagcttgta gcatatttgt taattgagca aaggcgctag
     4321 aagagtttgc tgggtcagca gttgcgattt ttccttttag ttcaggtttg agaaggtcgc
     4381 tatatccttc gatgttcatg cctttagtta aatcagggtg gacgattaaa acactaccat
     4441 ctagtgtata aggagtagag aagccagttg tgttttgata ttctttgata acattatcat
     4501 tttcttttga agtatagttt tcaaagagtt ctccgtgggt agcatattgt gtataagaac
     4561 caccaaagat aacatcagct acaggaactt ctttttctga ctctagtttt ttgaaaagtt
     4621 ctccagtacc agcttgaatc agttctactt tgataccata tttttcttca aaggcaggaa
     4681 tagttgctcc aattaagtcc tctgagtttg gtcaataaac gactagcgaa ccaccgtctc
     4741 ctttatcaga tgaactgtca tcggcagatt cattagaaga acaagcagca taatacatcc
     4801 atttcttttt catgatggga tatctccgtt gtgttattta agtttatttt aaaacaatgt
     4861 aagcgttttt aaaacctaca attctattct atagtgtatt gaatctataa cagtacactt
     4921 tgactgctaa aatatttcta taaattaatt tgactttcct gatagagatg ttcacatctt
     4981 atttcaattc actatattag agtaaaattc tctacaaaaa gaagaatagc ctattttact
     5041 attcttccga gtgatttcaa tttctttggg gaaatatgga gatacttttt aaatactttg
     5101 gcaaaatatt tatagtctga aaatccaact tggtcagaga tagcgcttaa aggggagttg
     5161 ggagattcag ccatcttatc tatagcttgt ttcaggcgat attgtaagat atattcattt
     5221 agagtcatgg ggaagtcttc tttgataacc ttatatagat gcttgttatc tgcaaatagc
     5281 tagagcattt caaggaaatg aactagaaat aacaattaat atggtggttc agaaatacct
     5341 tttgataatc aataagatct tcaggatgaa gtgcgttgac tccatccatt tcatatttcc
     5401 gatttaataa acgatatttg ttttcaccaa attgatgaaa agggagtagt tgaacttggt
     5461 cgatatttaa tgagttaaat agagtagcga atttttctgc atcctctaaa ctattgttaa
     5521 aattaggaat aactgggatt cttaaaacga tagttttatt ttgagaaaaa gcataatgaa
     5581 tgtttttaat aatcatttga ttaaaaaccc cagtcacttt tttatgtttt atagaattat
     5641 aatgttttag gtctgtgtag ataaaatcca catattgaat taaatcgata aatttttcat
     5701 gatcaacaaa ggcagtagtt tcaatggcag tgtgtatgtg atgttcttta gctgatttta
     5761 agatggcttt agcaaattca aactgagcaa atatttcacc tcctgataaa gttaaacctc
     5821 caccggattc ttcgtaaaat tctttgtctt ttaatacctc tgtaataatt tcttctacag
     5881 tcttttcttc accgactaag gtgaatttct ctcgttgagc atctttcatt ttttcaggtt
     5941 tcattctttg agattcagga ttagaacacc atggacagcg cagaggacat ccttttaaaa
     6001 aaacagttgt acgaataccc gggccgtcat gaattgaaaa gtgttgaata ttaaaaataa
     6061 ttcctttaga tatttccata agagttcctc ctcttcataa gtctatccta tcacaaaaac
     6121 gaaagaaaaa caattacgaa cgaaaggttg atttgttgtt ttttgctttt tattttggta
     6181 gaataaaacg gaggtgtaaa atgaaaagat tggaacaaat tattaaatta gtatcagaat
     6241 atgaaaagat cgacgttaat acattatcgg aaaaattaaa tgtatcgaaa gtaacgatta
     6301 gaaaagattt agataaatta gagtcaaaag gtttattaca cagagagcat ggatatgctg
     6361 tattaaatag tggagatgac ttaaatgtac gtttgtcaat taattatgaa attaagagaa
     6421 aaattgttca ggaagcagta aaattggtgt cagataatga aacaataatg atagaatctg
     6481 gatcgacctg tgctttactt gctgaggaaa tttgcaagca aaaaagaaat gttacgattg
     6541 taacaaattc attttttata gcaaattttg tgagagctta tgattcatgt cgtattattg
     6601 ttcttggtgg agagtttcag aaggattcac aggttactgt gggaccttta ttaaaagaaa
     6661 tgatacagac ttttcatgtg catcaagctt ttgttgggac agatggttac gataaagaga
     6721 tgggctttac aggaaaagat ttaatgcgca gtgaggtagt tcaatatatt tcagcagcgt
     6781 cggataaagt cattgtacta actgactcaa gtaaatttga taaaaggggt acagtaagaa
     6841 gatttgcttt aagtcaagtc tatgaagtaa taacagacga aaaactttct aaacaaaata
     6901 tagctacatt agaaaatgct gggataatgg ttaaggtagt ttcgtaagag gttaagtgta
     6961 tgaatcaaga taggaataaa ctgctctcta aaattgctta tctgtattat attgaaaact
     7021 taaatcagtc acaaatagca gcaaaattag gaatttatag aacctctatt agtagaatgt
     7081 taacagaagc aaggaatgca ggaattgtta aaattgaaat agagaatttt gatacaaata
     7141 tgtttaagtt ggaaaattat gtaaaagaaa aatatggtct ggaaagttta gaaattattc
     7201 caaatgaatt tgatgataat ccaacaattt tatctgaaag aatttctcaa gttgcagcag
     7261 gtgtccttag gaatttaatt gatgataata tgaaaattgg cttttcttgg gggaaaagtt
     7321 taagtaattt agtagattta attcacagta aaagtgtccg aaatgttcac ttctatcctc
     7381 tagcaggtgg tcctagtcac atacacgcta aataccatgt gaatacactg atttatgaaa
     7441 tgtctagaaa atttcatgga gagtgtacat ttatgaatgc aacgattgtg caagaaaata
     7501 aattgttagc agatggtatt ttgcaatcaa gatattttga aaatttgaaa aatagttgga
     7561 aagatttaga tatagctgta gtcggaattg gtgattttag caataaagga aaacatcaat
     7621 ggttagacat gcttacagag gatgacttta aagaattgac caaagttaaa actgtaggag
     7681 aaatttgttg tcgatttttt gattcaaaag gtaaagaagt ctatgaaaac ttacaggaaa
     7741 gaacgatagc aatctctttg gaagatttaa aaaatattcc tcaaagttta gctgttgctt
     7801 acggtgatac gaaagtatct tcgattcttt ctgtcttgcg tgctaattta gtaaatcatt
     7861 tgattacaga caaaaataca attttaaaag ttttggaaga agatggggat ttgactttta
     7921 gagagattct aggtgagtga aaatgataga ctgattcagt ttatcgtttt tctttttagt
     7981 tgattgcaca tttgtgctta tataaacaaa aatagtttat ctgttgtttt tggattgaca
     8041 actttattat gtagttgtat tctatagtta caaaagaaaa ttttaaaatt tcaaatgaaa
     8101 aaagcttttt acatagtgaa atgaggagga atttatggaa attattgttc cagatcaaat
     8161 tatcatgggt ttaattttat atgctggcga tgcgaaacaa catatttata aagcgttaga
     8221 ttacataaaa aatggtacat gtgaacgatg tgaagaagaa atccagttag ctgatgcagc
     8281 cttattagaa gctcataatc tacaaacaaa attcttggca caggaagcgt ctggtacaaa
     8341 gacagaaatt acagctctct ttgttcattc acaagatcat ctcatgacta gtatgacgga
     8401 gattaattta atcaaagaaa ttattagttt gagaaaagaa cttcataaaa aataatacta
     8461 gagtattatc attgttatta acatagagga ggaaaacata atggtgaaga ttggtttgtt
     8521 ttgtgcagca ggtttttcta ctggtatgct tgtaaataat atgaaaattg cagcgcaagc
     8581 tagtggagtt gaggcagaaa tagaggcgtt ttctcagtct aaattagcgg attatgcgcc
     8641 aaatatagat gttgcactat tgggtccaca agttgcttat acattagata aatcaaaaga
     8701 aatttgtgat aagtgtgatg ttccgatagc tgttattccg atgatggact atggtatgtt
     8761 agatgggaaa aaagtattag atttggccct atctttgatt agtgggtaag aaaaggagat
     8821 ttattatggc aaagatggat gttcagaaaa tcattgcacc gatgatgaag tttgtgaata
     8881 tgcgtggcat tatagctcta aaagatggga tgttagcaat tttgccattg acagtagttg
     8941 gtagtttatt cttgattatg ggacaattgc cgttcgaagg attaaataag agcattgcta
     9001 gtgtttttgg agctaattgg acagagccgt ttatgcaagt atattcagga acttttgcta
     9061 ttatgggtct aatttcttgt ttttcaattg cctattctta tgctaagaat agcggagtag
     9121 aggctttacc agctggagtt ctatctgtat ctgcattctt tattttgcta agatcatctt
     9181 atatccctaa acaaggtgag gcaattgggg atgctattag taaagtttgg tttggaggtc
     9241 aaggaattat cggtgctatc attataggtt tggtagtagg aagtatttat accttcttta
     9301 taaagagaaa aattgttatt aagatgccag aacaagttcc acaagctatt gccaaacagt
     9361 ttgaagcaat gattccagca tttgtaattt tcttactttc tatgattgta tatattttag
     9421 cgaagtcatt gactaatggc ggaacattca tagaaatgat ttattctgct attcaagttc
     9481 cattgcaagg tttaactgga tctttgtatg gtgctattgg aattgcattc tttatatcat
     9541 ttttgtggtg gtttggtgtt catggacaat cggtagtaaa tggagtagtg acagctctgc
     9601 ttttatctaa tcttgatgct aataaagcta tgttagcctc tggtaatcta tcattagaaa
     9661 atggtgcaca tattgttact caacaatttt tagattcatt tttaattcta tcaggttcag
     9721 ggattacgtt tggtcttgta gttgccatgc tttttgcagc aaaatcaaaa caataccaag
     9781 ccttaggaaa agttgccgct tttccagcaa tatttaacgt aaatgagcca gttgtatttg
     9841 gatttccgat tgtcatgaat ccagttatgt ttgtaccttt cattcttgtt cctgtacttg
     9901 cagctgtgat agtatatgga gctattgcaa caggtttcat gcagccattc tcaggggtaa
     9961 cattgccttg gagtacacca gctattttat caggattttt ggtgggtgga tggcaaggag
    10021 ttattactca gctggtgata ttagcgatgt ctacattggt ttattttcca ttctttaaag
    10081 tacaggatcg tttagcttac caaaatgaaa tcaaacaatc ttagaggtat ttgtgtgtta
    10141 ctgttaaact cacacatttg tgctaaaaat tagagagtta aaatttttct agttaaaagc
    10201 ttgaaaattt ctataaaaat cggtattata ttttcgaaag aaataaaaat attttcgaaa
    10261 gaaaggtggt tacgatggta aatacagaag tagcaagaac aacaatcaag acagaatatt
    10321 ttggcagcct tactgaaagg atgaacaaat atcgagaaga tgttttaaat aaaaaacctt
    10381 atattgatgc tgagagagca gttctagcaa cacgcgccta tgaacgatac aaggaacaac
    10441 ctaatgtcct aaaacgtgca tatatgctga aagaaatttt ggaaaatatg actatctata
    10501 ttgaagaaga atctatgatt gggggaaatc aagcttcttc caataaagat gctcctattt
    10561 ttccggaata tacgctagaa tttgttctca atgagttgga tctttttgaa aagcgtgatg
    10621 gagatgtttt ctatattaca gaagaaacaa aagaacaact tagaagtatt gctccgtttt
    10681 gggaaaataa taatttacgt gctagagctg gtgccttatt acctgaagaa gtgtctgttt
    10741 atatggaaac aggattcttc ggtatggaag gtaagatgaa ttctggagat gctcacctag
    10801 cagttaacta tcagaaactt ttgcaatttg gcttaagagg ttttgaagag cgggctcgta
    10861 aagcaaaagc agctctagat ttaacagatc cagcaagtat tgataaatat catttttacg
    10921 actctatatt tatcgtaatc gatgctatta aagtatatgc aaagcgcttt gttgctcttg
    10981 ctaaaagttt agccgaaaat gcaaatccta aacgtaagaa agaattactt gagattgcag
    11041 atatttgctc tagagtccca tatgaaccgg taactacttt tgcagaagct attcaatcag
    11101 tttggtttat tcaatgtatt ttacaaattg aatctaatgg ccactctctt tcatatggcc
    11161 gttttgatca atatatgtat ccatatatga aggctgattt agaaagtggt aaagaaacag
    11221 aagatagcat tgttgaacgt ctgacaaatc tttggattaa gacaattaca attaataagg
    11281 ttcgcagtca atcacataca ttttcttcag caggaagtcc tttatatcaa aatgttacaa
    11341 ttggtggaca gactcgagat aagaaggatg ctgttaaccc attatcttat ttggtattaa
    11401 aatcagttgc acaaacccat ctaccgcaac ctaatctaac tgtacgttac catgcaggtt
    11461 tagatgctcg tttcatgaat gagtgtattg aagtgatgaa acttggtttt ggtatgcctg
    11521 catttaataa tgatgagatt attattcctt cttttattgc aaaaggagta ttggaagatg
    11581 atgcttatga ttacagtgcc attggatgtg ttgaaacggc agttccaggg aaatggggct
    11641 atcgttgcac aggtatgagt tatatgaact tccctaaggt tctacttatc acgatgaatg
    11701 atggaattga tccggcttcg ggtaaacggt ttgcaccaag ctttggtcat tttaaggata
    11761 tgaagaactt ttctgaatta gaaaatgctt gggataaaac actaagatat ttgacacgaa
    11821 tgagtgttat tgttgaaaat tctattgatt tatcattgga acgagaagtt cctgatattc
    11881 tatgttcagc attgactgat gattgtattg gtcgtggaaa acaccttaaa gaaggtggag
    11941 cagtatatga ttatatatca ggattgcaag ttggaattgc aaatttgtcg gattcattag
    12001 ctgcaattaa aaaattggtg tttgaggaag aacgtataag cccaagtcag ctttggcatg
    12061 cactggaaac agattatgcc ggagaagaag gtaaggtcat tcaagaaatg ttgattcatg
    12121 atgcacctaa gtatggtaat gatgatgatt atgctgacaa attggttact gctgcttatg
    12181 acatttatgt tgatgaaatt gctaaatatc ctaatacacg ttatggaaga ggtccaattg
    12241 gaggaattcg ttattcagga acatcttcta tctcagccaa cgtagggcag ggacgtggaa
    12301 cattagcaac tccagatgga cgcaacgcgg gtacaccgtt agcagagggt tgttcaccat
    12361 cacataatat ggatcaacac ggccctacat ctgttttaaa atctgtttca aaattaccaa
    12421 cagatgaaat cgtaggtggg gttctcttaa atcagaaagt aaatcctcaa acgttagcca
    12481 aagaagaaga taaattaaaa ctaattgctt tgttacgaac attctttaat cgtttacatg
    12541 ggtaccatat tcaatacaat gttgtttcca gagagacgct gattgacgct cagaaacatc
    12601 ctgaaaaaca cagagactta attgttcgtg ttgcaggata ctctgcattc ttcaatgttc
    12661 tttctaaggc aacccaagat gacattatag gacgtactga gcatactttg taaaataaag
    12721 aggttctttt tatggaattt atgcttgaca cattaaattt agatgagatt aaaaagtggt
    12781 ctgaaatttt gccgctagct ggggtaactt caaatcccac tattgcaaaa agagagggtt
    12841 ctattaattt ttttgaacga atcaaagatg taagagaatt gattggctct acaccctcta
    12901 ttcatgttca ggtgatttct caagattttg aaggcatctt aaaggatgct cataaaattc
    12961 gaagacaagc aggagatgat atatttatca aagtacctgt tactccagct ggattacgtg
    13021 caataaaggc gctaaaaaaa gagggctacc atatcactgc aacagctatt tatacagtta
    13081 ttcagggatt attagctatc gaagcaggag cggattacct agctccatat tataatagaa
    13141 tggaaaatct gaacattgat tcaaattctg tcattcgtca attagctctt gctattgata
    13201 gacagaactc tcctagtaag attttagctg catcctttaa aaatgtagca caagtaaata
    13261 atgctttagc tgcaggtgcg catgctgtta cagcaggagc ggatgttttt gaatcagctt
    13321 tcgccatgcc atctatccaa aaggcggttg atgatttttc tgacgattgg tttgttattc
    13381 aaaatagtcg ttccatttag atagagagga aatacatatg agaatttttg ctagtccttc
    13441 tagatatatt cagggggaaa atgccttgtt tgaaaatgcc aaatcaattt tggatttggg
    13501 aaattgccct attctattat gcgatcagtt ggtttatgat attgttggaa aacgatttga
    13561 agattatcta cataggtatg gtttccatat tgttctggcg ctatttaatg gtgaagcttc
    13621 tgacaatgaa atcaatcgag ttgttgcctt ggctgagaaa gaaaattgtg atagtattat
    13681 cggtcttggt gggggaaaga cgattgatag cgcaaaagct attgcagatt tgattgaaaa
    13741 gcctgttatt attgctccaa caattgcatc gaccgacgca cctgtatctg ctttatctgt
    13801 tatttataca gatgaaggtg catttgatca ttatctattt tattctaaaa atccagattt
    13861 agttttggtt gatacaaaag ttatttcaca agcccctaag cgtttattag cgtctggtat
    13921 tgcagatggt ttagcaactt gggttgaggc gcgtgcggtt atgcaggcaa atggaaaaac
    13981 tatgttggga caacagcaaa cattggctgg agttgcaatt gcgaagaaat gtgaagaaac
    14041 gctgtttgca gatggtttac aggctatggc agcttgtgaa gctaaagtgg tgacaccagc
    14101 attagaaaat attgttgaag ctaatacttt attgagtggt ctaggttttg aaagtggagg
    14161 attagctgcg gcgcatgcaa ttcataatgg ttttactgca ttgacaggtg acattcatca
    14221 tttaacacat ggtgaaaaag tagcttatgg aactttagta caactattat tggaaaatag
    14281 acctaaagaa gaacttgata agtatattga gttttacaaa aaaattggta tgccaacaac
    14341 tataaaagaa atgcatttgg atcaagttgg atatgatgat ttaataaaag ttggtaaaca
    14401 agcaactatg gagggtgaga caattcatca gatgccgttt aagatttcgc cttcagatgt
    14461 tgctcaagct attatcgctg tagatgccta tgtaaattca aaataaacaa taaggactac
    14521 tgttttccaa atggtagtct tttattgatc ctcgtattga attctatagc agattgaaat
    14581 aagatgagaa caaatcgatt gggaaagtaa aattaatttc tataagtgtt ttagcaattg
    14641 tttcgtacta tttcagattc agtctactat acgttcttca taaatcaaaa agcgacatag
    14701 gttgtcggct atttattgtg aatacattaa ttag
//
LOCUS       DAVLZG010000052        14164 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLZG010000052 DAVLZG010000000
VERSION     DAVLZG010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.052"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            81..878
                     /locus_tag="VYO72_001606"
     CDS             81..878
                     /locus_tag="VYO72_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1707944.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..2285
                     /locus_tag="VYO72_001607"
                     /pseudo
     CDS             1026..2285
                     /locus_tag="VYO72_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2381..3655
                     /locus_tag="VYO72_001608"
     CDS             2381..3655
                     /locus_tag="VYO72_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1707945.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VYO72_001609"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VYO72_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1707946.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VYO72_001610"
     CDS             4784..5086
                     /locus_tag="VYO72_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1707947.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VYO72_001611"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VYO72_001611"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1707948.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VYO72_001612"
     CDS             5960..7300
                     /locus_tag="VYO72_001612"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1707949.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VYO72_001613"
     CDS             7278..7490
                     /locus_tag="VYO72_001613"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1707950.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VYO72_001614"
     CDS             7487..8362
                     /locus_tag="VYO72_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1707951.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VYO72_001615"
     CDS             8355..9170
                     /locus_tag="VYO72_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1707952.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VYO72_001616"
     CDS             9163..9594
                     /locus_tag="VYO72_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1707953.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VYO72_001617"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VYO72_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1707954.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDMTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VYO72_001618"
     CDS             11270..11998
                     /locus_tag="VYO72_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1707955.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VYO72_001619"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VYO72_001619"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1707956.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13981..>14164)
                     /locus_tag="VYO72_001620"
     CDS             complement(13981..>14164)
                     /locus_tag="VYO72_001620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707957.1"
                     /translation="QTRKLAAGYSKHSFEVVDKTDEVSSKHGFEVVDETDEVSNHTYG
                     KATMTWFEEIFEEYKN"
BASE COUNT         4182 a         2584 c         3366 g         4032 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cagaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgat acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaatga tatggaggtc
     1021 accttatgac ttgtgatttt aaatctgaaa ctctacaact acatgctggt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatgttgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa acttgtcttg attgaaacct tgggtaactc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaatacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gatggcttca gggaaattcc ctcaatttgt tgacgagggt tcaagctgcc
     1741 acaatttgag ctatactcgt gatgtgggtg cagtagcctt tattatagtt gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac cctttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttattatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tgacgaggaa gaagcacgca aggtcattga tcatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca atcactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaatcaa atccacttgt
     2221 ctatcggtct tgaaaatgta gaagatttga ttgaagactt acgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggtt ttgactcact gtttttgatt ttccttcatg
     2341 catgatataa tggttacaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc
     2521 ggagcaaaag gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt
     2641 tgaacagaca agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa
     2701 tcagttggct accttgcgtt tggagcatga aaatcaacta caaaagaccc tttctgacct
     2761 agaaaaagaa cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt
     2821 atctttggct tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcagacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagatttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aattactctg ggttattcca cgacgactga
     3901 ggatgctagt ggggaagtga tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gctcgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaacacc aatcggtcat
     4921 ggccgatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgtatt attcgtcgta tcaagcgtga tatggaggaa
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccataa aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaaatatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc taccccaatt
     6361 ttctaagaga attggggtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatcctacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttaactcatt tgcaaaatca
     6781 ggaaaaacgg atggcaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagatca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttgccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagattaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggt aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attggaagaa attgcccagc aggttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgataccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attaccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gatacttttg cagacaagat ttttagttgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gccttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagct atgaatgaca tggaaagtgt cgaagagtat
    10381 gatcctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctgatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgctaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaatgaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagtatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caatttttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acagtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tatgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc tcaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcggcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atctttgttc acgcaggtat
    11701 tgatttgacc ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacaggaga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg aaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggagaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 gattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggttttcgt tgtggatttc ttggacttct
    13141 ccatatggat gttatccagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcaa cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgctct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taagaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc atcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa ccatgttttg agctgacttc
    14101 gtcagtctta tctacaacct caaaactgtg ttttgagtaa cctgcggcta gcttcctagt
    14161 ttgc
//
LOCUS       DAVLZG010000053        14112 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLZG010000053 DAVLZG010000000
VERSION     DAVLZG010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.053"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(1..345)
                     /locus_tag="VYO72_001621"
                     /pseudo
     CDS             complement(1..345)
                     /locus_tag="VYO72_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
     gene            complement(454..1590)
                     /gene="lctO"
                     /locus_tag="VYO72_001622"
     CDS             complement(454..1590)
                     /gene="lctO"
                     /locus_tag="VYO72_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1707958.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(2215..3705)
                     /gene="lysS"
                     /locus_tag="VYO72_001623"
     CDS             complement(2215..3705)
                     /gene="lysS"
                     /locus_tag="VYO72_001623"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1707959.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(3833..3979)
                     /locus_tag="VYO72_001624"
     CDS             complement(3833..3979)
                     /locus_tag="VYO72_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1707960.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            4012..4929
                     /locus_tag="VYO72_001625"
     CDS             4012..4929
                     /locus_tag="VYO72_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1707961.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFG
                     LARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFW
                     IYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            4930..5688
                     /locus_tag="VYO72_001626"
     CDS             4930..5688
                     /locus_tag="VYO72_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1707962.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMHPE
                     IILFDEVTASLDSEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAHAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            5700..6572
                     /locus_tag="VYO72_001627"
     CDS             5700..6572
                     /locus_tag="VYO72_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1707963.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLARKTSSTRPMKKHFTQPTVTLLK
                     QMTWLLKVEKLISH"
     gene            complement(6652..7299)
                     /locus_tag="VYO72_001628"
     CDS             complement(6652..7299)
                     /locus_tag="VYO72_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707964.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(7296..7994)
                     /locus_tag="VYO72_001629"
     CDS             complement(7296..7994)
                     /locus_tag="VYO72_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707965.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(8004..8756)
                     /locus_tag="VYO72_001630"
     CDS             complement(8004..8756)
                     /locus_tag="VYO72_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707966.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(8756..9520)
                     /locus_tag="VYO72_001631"
     CDS             complement(8756..9520)
                     /locus_tag="VYO72_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707967.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMVVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(9616..10019)
                     /locus_tag="VYO72_001632"
                     /pseudo
     CDS             complement(9616..10019)
                     /locus_tag="VYO72_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10199..10831)
                     /locus_tag="VYO72_001633"
     CDS             complement(10199..10831)
                     /locus_tag="VYO72_001633"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1707968.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(10865..11566)
                     /gene="pyrF"
                     /locus_tag="VYO72_001634"
     CDS             complement(10865..11566)
                     /gene="pyrF"
                     /locus_tag="VYO72_001634"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1707969.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            11887..11979
                     /locus_tag="VYO72_001635"
                     /pseudo
     CDS             11887..11979
                     /locus_tag="VYO72_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12301..13014)
                     /locus_tag="VYO72_001636"
     CDS             complement(12301..13014)
                     /locus_tag="VYO72_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1707970.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFCKYLMETQG
                     KVNDQQELVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(13007..13846)
                     /locus_tag="VYO72_001637"
     CDS             complement(13007..13846)
                     /locus_tag="VYO72_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1707971.1"
                     /translation="MSMIEVSHLSKSFGDKIALNNISFTVKEGQIFGFLGPSGSGKTT
                     TINILTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSK
                     FYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSG
                     LDPTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELI
                     QRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGK
                     LNA"
BASE COUNT         4532 a         2910 c         2391 g         4279 t
ORIGIN      
        1 gtctaaaaat ctctcatcca acgaacctat ccagtaccca ctcggttgat tagataattt
       61 tctgattttt tgtaaaataa tttttttatt taaaacacta tttgtaccaa ttggatcttt
      121 tatctcattt ttcccttttt caaataagtt atctactcta tgatccgtta tttccatttc
      181 gtttactaac atgacgcagt cacctagcat catatactcc aacttttttt ctgaaagttt
      241 agcaaatata aaagcaaatg ttggtaagcg ataatatagt atattgaaac tagaatagta
      301 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      361 ttcttatttc attttactat agttttcgat agcaatttat tcttccaata cacgaagaaa
      421 aacctccaca ttcagtggag gcaatctgtt ttatcaatac aattttaagt cacgagggtc
      481 aactgggaag gttgggttgt atggattgtg acggagctta aagtgtttga catcttcaat
      541 ggtctgagct ccagacaatt gcataactgt cttcaattcc gcattcaagt gttcaaagac
      601 ttgacgcaca ccgacactac caccgagagc caagccataa ataacagggc gaccaatagc
      661 taccaagtct gctcctgaag ccaaggcttt aaagacgtgt tgaccacgac gaacaccaga
      721 gtcaaagaca atcggcacac gtctatcaac tgcttctgcc acttcttgaa gcgagtcaaa
      781 ggcagctggt ccaccgtcga tttgacgacc accgtggttg gttacccaga taccagaagc
      841 tcctgcagca agtgaacgtt caacgtcctc acggcattgt ggtcccttga catacacagg
      901 aagaccagag tattcagcga taaattctac atcgcgtgga gacaagcgtt gtttagctga
      961 tttgtaaaca aagtccattg atttaccagc accttctggc aggtattctt caacaatcgg
     1021 catgccaact gggaagacaa aaccattacg cttatccact tcacgattcc cccctacagt
     1081 agcatctgcc gtcaagacaa tcgctttata accttcagcc ttcacacggt ccatgatgtg
     1141 gcggttgata ccgtcatcct tactaaagta aaattggaac caatggggtg tcccttgaag
     1201 ggcttcagaa atctctggaa ggtcaacagt agagtaagag ctggttgtat aaagagaacc
     1261 aaactcatgc acaccacgcg cagtcgccac ttccccctgt tcatttgcca atttatgagc
     1321 cgcaacaggc gccataatga ttggtgaaga tagtttttca cctgcaaatt caatctctgt
     1381 acttggattt tcaacatcgc aaagtgtatg aggaacgatg agtttgtggt taaaggcgcg
     1441 gatattctct cttaaagtga aagtatcttc cgccccacta gcgatatagc caaatgctgc
     1501 tttaggaata acttgttgcg ccattggctc caaatcatag gtattgatga agtctacatg
     1561 accttctgca ttgcttgttt tgtatgacat aaaatgccct ccttgattaa gtaagcgttt
     1621 gctttttact acacaactat aataactctt ttttcaatca ttttcaagag ttttgcttaa
     1681 aaaccatctt attttttcat acaatatact agccctactt tccttaaact ctaaacttta
     1741 gtctatatta agtgaatcgt tgagattttt tgctgccagg catttgaact acttttttat
     1801 ttgcggattc tatctactaa tactataaaa aaacaagtga ataagacacc agaacatcct
     1861 ctaataggac ctatggactt atatcagtcc catatatact gtttaagcaa gatactatcc
     1921 tagttgacgc taacttccta tcccacttat taatttttta tttatagtga atctgaacaa
     1981 atcaattggg gaatccaagt caatttctag tactttttga acagtttcag cgtactatcg
     2041 taaaatgaaa taaaacatgc acaaattgct tagggaattt aaaccaattt ctaacaatgt
     2101 cttagaaatc aaagtgtact atttcaactt caatatacta cacttcattt tctccttaaa
     2161 ttcagtctct ttttgaatca aaaaatcccc tggtaagagc cagaggataa gaatttattt
     2221 cattgttggg aagagcaata catcacggat agttgttgta tcagtgagga gcatgcagag
     2281 acggtcgata ccgattccca aaccacctgt tggtggcata ccgtattcaa gagcttcaat
     2341 gtagtcatag tcgattcctg tcgcttcatc atcaccaagt tctttggctt tagcttgggc
     2401 ttcaaaacgg ctaagttggt cgattgggtc gttcaactca gtaaaggcat taccgtactc
     2461 cttagtcatg ataaagagct cgaaacggtc agtaaagcgt tggtcttcag gatttttctt
     2521 agcgagtgga gatacagcta ctggatgtcc atagacaaag gttggttgga ttaaagtttc
     2581 ttcaacaaac tcttcaaaga aggcattgat gatgtgacca acctcagtgt agtgtttctc
     2641 aactggaact ttcttctcag cagcgatagt tttagcttct tccaaagtca tgtcttgcca
     2701 gaaatcgaca ccagtaattt ctctgatagc atccaccata tgaacacgct taaatggttc
     2761 gttaatcttg atttcagtac cttggtagtt gactgggcca tcgcctttga ctgatttagc
     2821 agcatgttgg ataatgcctt ccgtcaagtc catgatatct tggaagtctg cataagcttg
     2881 gtaaacttcg atagaagtga actcagggtt atgagtagcg tccattcctt cgttacggaa
     2941 gatacggcca atttcataga cacgttccat accacccaca ataaggcgtt ttaagtgaag
     3001 ctcagtcgcg atacgaagca ccatgtcaat gttttgggca ttgtggtggg tgataaatgg
     3061 acgggcagca gcaccaccgg cttcattatg aagaacaggt gtttccactt caaggaatcc
     3121 tttttggtca aggtaacgac ggatttcaga gatgattttt gaacgagtga caaagcgttc
     3181 aaagctttca cgattagaaa tcaagtcaag gtaacgttta cggtaaattg tttcaacgtc
     3241 tgtcaaacca tggaatttct caggaagagg acgaagagcc ttagacaagt gtgtgatgtg
     3301 ggttgccttg atagagagtt ctcccatatc cgtacgcatc acttcacctt cgacaccaag
     3361 gaagtcacca aggtctgctt ttttgaagat ttcgtagttt tcttcaccga cagcatcctt
     3421 acgaacatag atctgaatct ggccttcgcg gtcttgaagg tgggcaaaac caacttttcc
     3481 tttaccacgt ttggttacca agcgtcctgc gatagtagct gtttcgtttt tatcgtgtaa
     3541 ttgttcttta tcgaggttgg catatttatc ttttaattct tgtgaatttg cagtacgttc
     3601 aaaacgtttt ccgaaaggat cgattccttg ttcgcggagc gcagccattt tttcacggcg
     3661 aacgatctgc tggtcattta gttcttccat atgttctgta gacatgggat cctcctagtt
     3721 ttactcaaaa ttgaatacga tgagtcattt tttgcgatac tcccatttta tcataaataa
     3781 gcaagaaatt cacggataat ctttaaaaac taaaaagaac ctgacgctaa aatcactgga
     3841 aagaagtgaa agtatcttcc gccccactag cgatatagcc aaatgctgct ttaggaataa
     3901 cttgttgcgc cattggctcc aaatcatagg tattgatgaa atctacatga ccttctgcat
     3961 tgcttgtttt gtatgacata aaatgcactc cttgataagt aagcgtttac tttgtatatt
     4021 gcagtttggg gaagtttggg atcctttctg ctcggtttaa tcgttagtat catccgacat
     4081 tatcgaatcc ctgttttggc gcaagtagcg acagcctaca ttgaattgtc acgtaatacg
     4141 ccccttttga ttcaactctt ctttctctac ttcggtcttc cccgaatcgg gattgtccta
     4201 tcttcagaag tctgtgcaac gcttgggctt gtctttttag gaggctccgc catgcaggat
     4261 tcgggaatcc aagtactctt tcaaggaaat aatctcctga gaatcttaca gggattgggc
     4321 gttacgattg ggatatccat cctgtctgtc ctcttatcca tgatgttcgg aacagtcatg
     4381 ggaatcatca tgacctccca ttctagaatc atacgatttt taacacgatt gtatctggac
     4441 tttacccgta tcatgcccca gctggtgcta ctcttcatcg tttactttgg cttggctcga
     4501 aactttaata tcaatatctc aggtgagact tcagctatta tcgtttttac cctctgggga
     4561 acagctgaaa tgggagactt ggtacgtgga gctatcactt ctctccctaa acatcagttt
     4621 gaaagtggac aagcactcgg cttgactaat gttcaacttt actaccacat catcatccca
     4681 caagtcttga gaagactgct accgcaggct atcaatcttg tcactcggat gattaaaacc
     4741 acttcattag ttgttttgat tggggttgtg gaagtgacca aagttggaca acaaatcatc
     4801 gatagcaatc gcctgaccat cccaactgct tcattttgga tttatggaac cattctagtc
     4861 ttatatttcg cagtttgcta ccctatttcc aaactatcca ctcacttaga aaaacattgg
     4921 agaaactaaa tgtctgaaac tatcttagaa atcaaggaac taaaaaaatc cttcggagac
     4981 aatcccatcc tccaaggact ttctctagaa attaaaaaag gggaagttgt tgtcatccta
     5041 ggggcatctg gttgtgggaa aagtaccctc cttcgttgcc tcaacggctt agaaagtatt
     5101 caaggtggag atatttttct ggatggtcag tctatcgttg aaaataaaaa agattttcac
     5161 ctagttcgcc aaaagattgg catggtcttt caaagttatg aactctttcc ccatctggat
     5221 gtcttacaaa acctcatcct aggccctatc aaaactcaag gaagggacaa gaaagaagta
     5281 acggaagaag ctttgcaatt actagatcgt gtcggtttgc tggataaaca acatagcttt
     5341 gcccgtcaat tatctggtgg acagaagcaa cgtgttgcaa ttgtccgtac cctcctaatg
     5401 catccagaaa tcatcctttt tgacgaggtg actgcttcgc tggattcaga aatggtgcgt
     5461 gaggtgctgg aacttatcaa tgatttggcc caagaaggcc gtaccatgat tttagtaacc
     5521 cacgaaatgc agtttgccca agccattgct gaccggatta tcttcctcga ccaagggaaa
     5581 atcgctgaag aaggaacagc tcatgccttc tttaccaatc cgcaaaccaa acgagcccag
     5641 gaatttttaa acgtctttga ctttagccaa tttggctcat atctataaag gagattctta
     5701 tgaaactatt caaaccactc ttaactgttt tagcacttgc ctttgccctt atctttatca
     5761 ctgcttgtag ctcaggtgga aacgctggtt catcctctgg aaaaacaact gccaaagctc
     5821 gcactatcga tgaaatcaaa aaaagcggtg aactgcgaat cgccgtgttt ggagataaaa
     5881 aaccgtttgg ctacgttgac aatgatggtt cttaccaagg ctacgatatt gaactaggga
     5941 accaactagc tcaagacctt ggtgtcaagg ttaaatacat ttcagtcgat gctgccaacc
     6001 gtgcggaata cttgatttca aacaaggtag atattactct tgctaacttt acagtaactg
     6061 acgaacgtaa gaaacaagtt gattttgccc ttccatatat gaaagtttct ctgggtgtcg
     6121 tatcacctaa gactggtctc attacagacg tcaaacaact tgaaggtaaa accttaattg
     6181 tcacaaaagg aacgactgct gagacttatt ttgaaaagaa tcatccagaa atcaaactcc
     6241 aaaaatacga ccaatacagt gactcttacc aagctcttct tgacggacgt ggagatgcct
     6301 tttcaactga caatacggaa gttctagctt gggcgcttga aaataaagga tttgaagtag
     6361 gaattacttc cctcggtgat cccgatacca ttgcggcagc agttcaaaaa ggcaaccaag
     6421 aattgctaga cttcatcaat aaagatattg aaaaattagc aaggaaaact tcttccacaa
     6481 ggcctatgaa aaaacacttc acccaaccca cggtgacact gctaaagcag atgacctggt
     6541 tgttgaaggt ggaaaagttg attagtcatt aactcttaaa aggaactgga ttttaagctc
     6601 caatcccttt ttaagatttt acctataaca tcctgagtct atctaagatg ttcaatctga
     6661 acacagtgta catactttat cttctattgc atatacttta tcacataaga tacgaatatc
     6721 ctcttcacta tgactagcaa tcaaaattgt tgtccctttt tcactagaga gctttctaaa
     6781 caatgttctc atattttcta cacttgattt atccaaggca ttcataggtt catctagtaa
     6841 aagaatagag ggattctcca taattgcttg agcaatccct agctttttcc tcatacctag
     6901 cgaataagtt ttaactttct ggtctttttg ctcatataga ccaactattt tcagtgtatc
     6961 attgatttcc tgattaccaa ctactcctcg tatgcttgcc aaatattgta aattcttaaa
     7021 gccactataa taatttataa aaccaggttc ttcaatcaaa gctcccaaat tagctggaat
     7081 ttttctctca ggaacaatat tttccccatt gattaacact tctccataag acggactata
     7141 taaaccagct attaatttaa acaatacact tttacctgag ccattcgcac cagtaattcc
     7201 tataatttcc ccctgtttac aactaaaatt aaggttttga aaaacacatg ttttttttaa
     7261 tttcaactca atatttttta atgtaattat ttcattcatt ctataaacct cctcttttga
     7321 cgagtgaaat agaaaatgct tttaaaaaga aagactaaaa atagcaactg aagaaataaa
     7381 tctcgtccta tatctccatt ccctcgattc aaaatataaa atagataatt agttcgattt
     7441 cctacaaata gaccaccaaa cacaatcatg agtaaaaaga aactaacgca agcaaagttc
     7501 atttgtacat tcgctcctag tgcgtataac ataaagcaaa gcaaggatag cacacaagca
     7561 ttcaaagaat caactataaa caaaactcct atatcccagt ttgctaactg taacataaat
     7621 tgaatcacta gaacttttac catgattaaa atgagtccat aaagaaaaca ggtccaaatc
     7681 tgatacctaa tccagagctt aatagaagaa aatcgaatca cttccataaa gaaatcggat
     7741 gctcttctac gatatacaac tgctagaaaa aatgtatgaa taataaacca atgaagcaac
     7801 catatagata agactaaaaa agagttttga ctcagattag gcccttttaa aatttctata
     7861 acaagtctat catttccttc taaccaatac cataatccta aacaaatcaa tatccaaaaa
     7921 agaacataac cccaaaagta cttggtatag attatctgat tcaacctcca catgtgacta
     7981 cttaactttc ccatttccaa cttttacact ctcctccagt ttctatgaac agaaaataca
     8041 gtcaatggaa ttatgataga tagtaatgta agccaataaa tcaatgcata cggattggaa
     8101 tttaccatat actgaaaaat tggcaataat ccaattatcc cattgttcaa ctgataaatc
     8161 cagaataagg attctacaaa taaaaaagta aacagaaata ctaagctcat gtttgatttt
     8221 ttaaaccaag aaaaactgct aatagtaagt aaggataaaa agaaatagta tgctatataa
     8281 gagaaaaaaa atcctataaa gaaactagca ttgtttgcaa tacttatacc ataaaattct
     8341 cttaaaaaat caacctcctt tatctccaaa gagaagctaa aaccattact aaatgcaatt
     8401 agaaaaatca ataaaaataa agtcgccgtc caaatccccg tactaagagc tgctaatttg
     8461 aaactaaaac tggtaaagtg cttaattgat ttcagacgaa tgcgacactc caacctatta
     8521 aaatagttat tcatcaaata aaaaaagaac aatatatatg tgaacggaaa gcaatatact
     8581 ccagtcgtca tatcttgaag taaaactaaa atccattcta atacatttgg atggattgaa
     8641 tattggcgac agcgcaataa atatactgta ctagataaaa cacaggatag cagtaatata
     8701 aaataaacca atactgctaa gaaatctttt ttataaaatt gaacaaattg tttcattata
     8761 catagtcctc tgaatgtaga aaaaatgtac cataaacaac caaacaacta acaaataaaa
     8821 taaaagcaag atgcccacta actaaggaaa gactgatatc tttctgatat cccaaagcta
     8881 gcgttgtcac aggttctaag taagatagcc ctaaaatagc ccataaaata ccaccaacca
     8941 ccatataggc aactgggatg aaaatagctc ctaatttttt cttcactagc aaagcactag
     9001 ctagtccaaa aatagagaac acagcgcccc aaactccata ccagagagtc gtcacaagac
     9061 tatagagaaa ctgattagaa tcaaataatt cttttaaggc accactataa tctccaatat
     9121 aaatttcctg ataaggagtc actaaaagat taattcctaa taataataaa taggggagaa
     9181 aaaagactag aaaagaagaa ataattgcag tactacctac aatagctaga tacctctttt
     9241 tagaaattcg gcacaattgt gctgttagaa aatgactctc agcatcctct attatctgac
     9301 tagaataggg cagtgtacag ataagtgcag ctactaggct aatcggtgaa aatcctcgaa
     9361 tagaagaagc ggcaaaaaaa atcgataaac cttcaatttt ataaatacca ttgaaagcaa
     9421 ggaaatttcc taaactcatg caaagaaggg tcaaaaataa agacatataa aaccgaggtg
     9481 attgaacgac tcgtacaaga ttacaaatga aaaattccat ccttactcct ccttataata
     9541 aaaatagggt gtagcattct tttttcatgc tacacccaca atcaaccatc tttaaggctt
     9601 actctgacaa gtaagttaat aagaatctgg actccaagaa cctgaagtat gaattcttac
     9661 atgatttcca aattgtggcg ccatagctaa tctagtacca gaaccaatat aattgtcacc
     9721 acctccatta tagtacatga caatcctaga gccagacccc aatgaatata ccggggtaat
     9781 atctgaccca ctataggcgc tacgaataga ggtatttaac cttttaccgc caccagtgct
     9841 gtcactatta ttaattccag cagaggcgtt ttctttctca agctcactag ttgtatccga
     9901 accccaacgc ggcaacgtta aatcataatt tccaatctgt ctagctaaaa ctgtagggag
     9961 aaacaaacta gatgcaattg taactacgca aaaaaggaat atatttttct tcttttcatg
    10021 acatcgtcct cttaagaagt gataaacaag atagttgatt gatcaatttg atacatatta
    10081 cattttcatt atatcaataa aagaaagcgt tgtcaattat tttatttaaa atattatcat
    10141 attttaaata aaatggtaaa agagactcgg tagcctcgtc tctctttatc ttactgacct
    10201 aaccttcttg ccaattttct tggtcttctt taaagcgttt tagaagatca aggccctctg
    10261 gcgtgatgta accttcttct tgggctagat ggataagctc gctatagttt gaaagcgtca
    10321 caagtttaac accagcatct gcaaagttct tatctgcttt tggcaattgg tagctgaaaa
    10381 tcgctacaac tccaagtaca tctgctcctt ctcgcttggc tgctgctaca gcttcaagaa
    10441 ctgaaccacc cgttgaaata aggtcttcaa ccactaccat tttttgacct tgagctacgc
    10501 gaccttcgat ttgattacca gctccgtggt cttttggttt gctacggatg taggcaaaag
    10561 gcaagtccat cttatcagca ataatggctc cgtgtggaat ccctgctgtt gcagttcctg
    10621 caatcacttc tacttcagga aaggcttctt tgatagcttc cacaaaacca ttttcaatta
    10681 gggtacgagt ttctggatag gctagtgtca cacgattatc agtgtaaatc ggtgacttga
    10741 taccagacgc ccaagtgaag ggttcctctg gtttgaggta aacggcttgg attttcaaga
    10801 ggtggctagc gatatcttta gcaagtgtca tggtattctc cttttatttt tctaatctag
    10861 ttctttaatt ccagtcctgt gtccattcat ccttgatggc atgataagct gcaacaggat
    10921 cctcagcttg ggtaatggga cgtcccacta cgatatagtc actaccaatt tgataagcat
    10981 ctgctggcgt catgacgcgt ttttggtctc caacagcagc tccctgtggg cgaatccctg
    11041 gtgtcagaca gataaaatct ggattggtgg cctgcttgat aagttgaact tcctgtgccg
    11101 agcaaacgac accatccaag cctgcttcag ctgtcttctt ggcatagtgg atcacagact
    11161 cttgtaggct tgtttggata ttttgaaact cctgcatctg ggcttctgat gttgatgtca
    11221 gctgcgttac agcgatcaat tttgcttgac ttccaagacc ttcacgcgca gccttcatca
    11281 tctctacacc accagccgca tgaacattgg tcatatcgac accaagctga gacaagacct
    11341 tcatggctga cttgactgta ttaggaatgt catgaagttt gagatccaaa aagacactat
    11401 gacccaaacc ttttaagtag gacacaatct caggccccgc tgcgtaataa agctccatcc
    11461 ctaccttgag ataaaggctt tcttctgctg ggaaaagagc taaaaattcc ttgaccgcct
    11521 caaaactagg aaaatcaaga gcaatgattg gacgatgttc tcgcataggt ttctcctttt
    11581 acctttacta gtgagagagt ctggccaaca gaagccacga aaaaaggaac ctgccaacag
    11641 caaggttcca cgaaaaatgg gtagtctcca ccctttcacc gtctaacctt agctgcctct
    11701 ctggactgct ttaaaggttt tctattattc tattatttct actagcactt gtcaagtaaa
    11761 aacatggtca cgtatgtgtt gactgctatt gaacacctca caagactctt tccaaaagaa
    11821 tagttaaaga ctttcactga ggacagagaa aaagagtttg cttgttaccc tttaattgaa
    11881 caaatgggaa ttctgtttta ttttgcggat gcctattcat cttggcaaag gggaagtaat
    11941 gagaatgcga atggacttct tcgtgagtat tttcttaaac cgatttggca acaattaccg
    12001 aaaaaatcct taatggtgct ttgctagctt attaatcacc gttcccaaaa atacttggat
    12061 tacaagacag gttttgaagc acttatagag gagatttaaa aatgttgcat tttttattgc
    12121 aatttatcag ttatcttatc acccaaaact tctgcaatta gtatgagcac tattgttatt
    12181 tttctttttt cgtacactca aatcaaaata tagcaataag actattctgt agaattgctg
    12241 tcaaaaagat cagttcattt ttccttccca cttgtgttta taatcattaa aataactcaa
    12301 ttaagaaatt ttctttttcc taatagttat cgtaattaaa gttaatagaa gaacaatcca
    12361 aataagtagt gttagattag gaattagagt ttcattccat gaaaatccct cccattttgt
    12421 gaaaaactta gtaaacagtc ccataaaact ataatctgtt atcttcgcaa ctgtcttatc
    12481 caaaccagat agcatcggta agaaagcaac taaaatcata gcaggaagac tgataacctg
    12541 agctactact tggctcttcg cggttaaacc tatcaataaa tagaataaaa tgatggataa
    12601 agaggttaga agaacgattg taatataatt aaaagtatgt acaattgtaa ctcctaaaat
    12661 aagaggagta gttcccataa tcacaaaagt tagcaaaaaa ggaagaaaca tcgttgataa
    12721 aatgtattcg gatcctttaa caccactcaa cagaagagtt tgtaaattgt acttttcttt
    12781 ttcttcagac aagataatag ttataggact tccaacagcc aaagccaaag aaaaaggtaa
    12841 acacatcatc aaaagaacta attcctgttg atcgttgacc ttcccctgtg tttccataag
    12901 atatttacaa aaatatgtga aagcaaaagg cactaaaact tgcaataaaa tactcttatt
    12961 ggaaaggata atttgacaac gcaaccatac caaagccaga aaccgtttaa gcatttagct
    13021 ttcctcctgt taatgtgata aaaatatctt ctaaagtagg ctcacatgaa tgaattgaaa
    13081 aaatattttc cagatcagcc tgagatacct gttctagtga tgtaaaatca aaagttatct
    13141 gattcccatt ataatctgta accttaatct ttttatcttt attatatctt tgaatgagtt
    13201 cagaaggagc tccttgctca actaatttcc ctttatttaa taaggcaaca taatcacata
    13261 aaagacttgc ttcattcata tcatgagtcg ttagaaaaat cgttgtccct gctgttttca
    13321 attctaaaat taactcatga attgttcgag aagttgtggg atctagacct gaggtcggtt
    13381 catccagaaa gagtacagcg ggtttgttga taagagctcg tgctaaaagc attcgttgcc
    13441 tcattccagt ggataatttt cctgctacca tcttgcgact atcatataat cctactcgct
    13501 ttaacaaatt atcaacacgt gatttactaa tattataaaa tttactataa aaaagaagat
    13561 tgttatacag agacattttc tcataaaatc cacttgtatc gctaaccaat ccaattctct
    13621 ttaattcacc gcttgttaaa ttttgagatt tttgtcccaa aataatagat tgtcctttat
    13681 cggcaaggaa ctgcccagtc agaatattaa tcgttgtggt ttttccagaa ccagatggtc
    13741 ctaaaaatcc aaaaatctga ccttctttaa cagtgaagct tatattattt aaagctattt
    13801 tatcaccaaa actttttgat aaatggctaa cttcaatcat actcattgca cctcctttat
    13861 attctacatt tttacttaac atctatttac ttagctttat caaataaacg tcttaaaaaa
    13921 aaacaataac attaagcata taaccgttag caagattgtt tcaatattat tgataatatg
    13981 atacattctc aagcagtata aaataattat atatatgcaa atgctcatta tacctatttt
    14041 tttaaacata ctaagcctcc ttgccaaata ataaagttat ataataacta agacacacta
    14101 tacctaacat aa
//
LOCUS       DAVLZG010000054        13703 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLZG010000054 DAVLZG010000000
VERSION     DAVLZG010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.054"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(116..2374)
                     /locus_tag="VYO72_001638"
     CDS             complement(116..2374)
                     /locus_tag="VYO72_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1707972.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2603..2833)
                     /locus_tag="VYO72_001639"
     CDS             complement(2603..2833)
                     /locus_tag="VYO72_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1707973.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3023..3706
                     /locus_tag="VYO72_001640"
     CDS             3023..3706
                     /locus_tag="VYO72_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1707974.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3706..4440
                     /locus_tag="VYO72_001641"
     CDS             3706..4440
                     /locus_tag="VYO72_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1707975.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4594..5451
                     /locus_tag="VYO72_001642"
     CDS             4594..5451
                     /locus_tag="VYO72_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1707976.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAMDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5593..6465
                     /locus_tag="VYO72_001643"
     CDS             5593..6465
                     /locus_tag="VYO72_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1707977.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6747..7430
                     /gene="rpiA"
                     /locus_tag="VYO72_001644"
     CDS             6747..7430
                     /gene="rpiA"
                     /locus_tag="VYO72_001644"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1707978.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7444..8655
                     /locus_tag="VYO72_001645"
     CDS             7444..8655
                     /locus_tag="VYO72_001645"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1707979.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8657..9199
                     /locus_tag="VYO72_001646"
     CDS             8657..9199
                     /locus_tag="VYO72_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1707980.1"
                     /translation="MTRYSLLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9215..10024
                     /locus_tag="VYO72_001647"
     CDS             9215..10024
                     /locus_tag="VYO72_001647"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1707981.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGGFKGLLKAILAEL"
     gene            10500..10895
                     /locus_tag="VYO72_001648"
     CDS             10500..10895
                     /locus_tag="VYO72_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1707982.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10905..11480
                     /locus_tag="VYO72_001649"
     CDS             10905..11480
                     /locus_tag="VYO72_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1707983.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11552..12016
                     /locus_tag="VYO72_001650"
     CDS             11552..12016
                     /locus_tag="VYO72_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1707984.1"
                     /translation="MELEGYNALSLAEVEVFRFIATNAETATQVSKPVQPISQTPVKD
                     KTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGCNQTAGFVLNLPIKENM
                     RNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTLNSKVSDDDVL"
     gene            12674..13384
                     /gene="deoD"
                     /locus_tag="VYO72_001651"
     CDS             12674..13384
                     /gene="deoD"
                     /locus_tag="VYO72_001651"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1707985.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13407..13640)
                     /locus_tag="VYO72_001652"
                     /pseudo
     CDS             complement(13407..13640)
                     /locus_tag="VYO72_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
BASE COUNT         4038 a         2518 c         3091 g         4056 t
ORIGIN      
        1 agattcagtc tactatatat cataatggac aaagggcaag ctgtcaagaa attacagtta
       61 ttttagtaaa aaaagaagca gaaaaatttc attttctact ccttttctat aggatttatt
      121 tttctttttc agaactttta acttcagctt ttttggcaga tttaatctga atgtttccct
      181 tgctagtcat aactgctttg agatcttttt cgcttggatt ttcaaggtag tagtcagtga
      241 ttgtgtcctc aatatagtct tgaatagtcc gacgaagtgg gcgtgctccc atttttggat
      301 cataacctag gtcaaccaac ttttccttga ccttatcagt tacatccaaa cgaatgttgt
      361 tgctagagag gcgcttgtta acatctgcta gcatgagctc gacaatctga aggaggttat
      421 ccttgctgag agccttaaat tcgataatgc catcaaaacg gttcataaac tctgggctaa
      481 agaagttacc gagttcaccg aggacagaat tggtacgtcc ttctctagca gcaccaaatc
      541 caacgctagc ttcggtcttt cctgtacctg catttgaggt catgataatg atggcatcct
      601 tgaagctaac ggtgcgtcct tgcccgtctg tcaaacgacc atcgtccaag acttgaagaa
      661 acatgtgcat aacatctggg tgagcttttt ccacttcatc gagaaggatg agagaatatg
      721 gattgtggcg aactttttca gttaattgac cagcctcatc atagccaaca taacctggag
      781 gggcgccgac caacttagcc acactatgtt tttccatgta ttcactcata tcaaagcgaa
      841 tcatactatc agcagaacca aaaagttcga tagccagttg tttggaaagt tctgtcttac
      901 cgacaccagt tggcccaacg aagaggaagc ttccgattgg gcggttaggg gtaccaagtc
      961 cgacacgatt acggcgaata gccttggcaa tcttatcgac tgcatcatct tggccaataa
     1021 catgagactt gagatcttcg gctagatgga tgagttgaga ttgttctttc tctttcaaat
     1081 caccaacagg gatattggtt ttctgctcga taatgtgctc aatagttttc tcgctgatga
     1141 taggagtatc ctggtctgtg atctttttct tttgcatttc cttatacttg gcaatctggt
     1201 cgcggaagta ggccgccttc tcaaaatctt cttctcgtgt agcttgagac ttgagatttt
     1261 cagcctcaat caagcgctga tcaattactt taggatccac aaaattcaag gtcaagttca
     1321 tcttagaacc agcttcatct aggaggtcaa tggccttgtc aggcaagaag cgatcttgga
     1381 tgtagcgatt ggaaagagtt gcagctgctt caatcgcagc atcggtatat tgaacgtggt
     1441 ggtaatcttc gtatttcttt tgaatccctt tgagaatagt gattgtttcg tccaccgttg
     1501 gttcatcgac tttaacaggc tgcatacgac gctcgagggc agcatccttt tcaatgatac
     1561 ggtattcatt gagggtagta gcaccgacta gttgcagttc tccacgagca agggctggct
     1621 tgaggatatt tcctgcgtcc atattaccat cactcgcaga accagcacca acaatttcat
     1681 ggatttcatc gataaagagg atgatgtctt cacgtttgcg aatttcttcc atgagttttt
     1741 gcatgcgttc ttcaaattgt cctcgaatcc ccgttccttg aactaagcta accacatcca
     1801 gacggatgac ttgtttacct tggagtttat gtggcacatc gccatcgaca attttctgag
     1861 ctagaccttc gacaacggcc gtttttccga caccaggttc accgataagg acaggattat
     1921 tcttggttct acgattgaga atctcgatga cacggataat ctcatcgtcg cgcccaataa
     1981 cggggtcaat gtctccacga cgggcaattt cagttacatt aataccaaat tcttccagca
     2041 ggcctttttc ttggctaggt ggcggagttt gagcagatcc acgattttgg gaaccataac
     2101 cgccgtttcc accgtaacct ccacctgatt gggttggggg aataggagga gtattgctag
     2161 aaggtctgaa attgtttaga tcattgaaga aatcaccaaa gggatcgaag tcacgattgt
     2221 tcagatccgt catacctttg aagaggctat tgttaggatc tgttttgata atcttatagc
     2281 agttttgaca gaggtcaatt tgtttttgtt ttccattgag attggtgtaa agatgaattg
     2341 ttgagtcgtt aattttacag ttttgacaaa gcatacatct acctcatttc tttctttagc
     2401 ctgacttgtt taaaggtcaa aaatagtcaa attctatact ctcattataa caggattggg
     2461 gtgtaaagca agtaaaaaga ttgaagcttt gagaagttgt tacaatgaaa atttttgtga
     2521 atttggacta taaaaaaatc ctatttgtga gacaaaaagg attttactta gacatgcagg
     2581 gacaatccca gcttgtttta gattagtaga gaagttcgta aatttccatt gcgattaagt
     2641 caatgctatc aaacgtatac gtttcgcgat cttctacgtc acgaagggta aagattgggc
     2701 cgttttcttc gtcgtggctg tacgcaactt ctgcaacaac aactccttcg cgttcaaaat
     2761 tacgttttaa atttccgcca tcgtttgcca ttgcttcaag gcggttgatg attctaacca
     2821 aatgtgattc cattttgatt ctccttcatt tcttatcgtt actattttac cataaaggag
     2881 gccaacttga ctagaaaaaa ctaagatttc tcactaattc tgctagttta aagattttta
     2941 aataaattgg ataaaagatt taaattttaa ttcaaaacat gttataatca tacagtattc
     3001 tattttagaa agcagtgtga ctatgaattt ttctttttta cctaagtatt taccttattt
     3061 taactatggg gctgttgtga cgattcttat ttctatctgt gttatctttt tgggaactat
     3121 tttgggtgtt gtcttggctt ttgggcaacg ttcaaagttt aaaccgcttg tttggttggc
     3181 caacttgtac gtttggattt tccgtgggac accgatgatg gttcaaatta tgattgcctt
     3241 tgctcttatg catatcaatg ctccgactat tcagattgga attttaggtg ttgatttttc
     3301 gcgtctgatt ccagggattt tgattatctc tatgaatagt ggtgcttatg tttcggagac
     3361 tgttcgtgcc ggaatcaatg cggttccaaa aggtcagcta gaggcggctt attcgctagg
     3421 gattcgtcct aaaaatgcga tgcgttatgt gattttgcca caagcagtca aaaatatctt
     3481 gccagcattg gggaacgaat ttatcaccat tatcaaggac agctccctct tatcagctat
     3541 tggggtcatg gagttgtgga atggggctac aacagtttct acaacaacct atctaccttt
     3601 aacaccactt ttatttgcag cattttacta cttgattatg acctctattc tgacagtagc
     3661 cttgaaagct tttgaaaaac atatgggaca aggagataag aaataatgac agaaaccttg
     3721 ataaaaattg aaaatttaca taaatctttt ggaaagaatg aagtattgaa gggcatcaac
     3781 ctcgagatta aaagaggaga agttgtcgtt atcatcggtc cttcagggag tgggaaatct
     3841 accttgcttc gctctatgaa tttgttggag gaagcaacca aggggaagct tatctttgag
     3901 ggagtcgata ttacggacaa gaagaatgac ctgtttgcca tgcgtgagaa gatgggcatg
     3961 gttttccaac aatttaacct ctttcctaat atgactgtga tggaaaatat taccttgtca
     4021 cctatcaaga ctaaaggtga aagcagggaa gttgctgaga agagagccca agagcttttg
     4081 gaaaaagttg gtttgccaga taaggcagac gcttatccac agagtctgtc gggtgggcaa
     4141 caacaacgga ttgccatcgc gcgtgggttg gctatggaac cagatgtttt gctctttgac
     4201 gaaccaactt cagccttgga tcctgaaatg gtaggtgagg tattggctgt tatgcaagac
     4261 cttgccaagt cagggatgac tatggttatc gtaacacatg agatgggatt tgcccgtgag
     4321 gtggcagatc gtgttatctt tatggcagac ggtgtggttg ttgaagatgg gacacctgag
     4381 cagatttttg aacaaaccca agaacaacgg actaaagatt tcttgagtaa ggttttataa
     4441 tctattttaa aatttcaaga caagattagt gaaaagttca accagagctt tttcttatag
     4501 tttgaaacta taggataacc taggaaagaa gtgttagagg gcactagcag tttttggtat
     4561 aatggaagat atttgaaaga aaagagaagt gatatgacac agattattga tgggaaagct
     4621 ttagcggcca aattgcaggg gcagttggct gaaaagactg caaaattaaa ggaagaaaca
     4681 ggtctagtgc ctggtttggt agtgattttg gttggggata atccagccag ccaagtctac
     4741 gttcgcaaca aggagaggtc agctcttgcg gctggttccc gtagcgaagt agtgcgagtt
     4801 ccagagacca ttactcaaga ggaattgtta gacctgattg ctaaatataa tcaggatcca
     4861 gcttggcatg ggattttggt ccagttgcca ttaccaaaac atatcgatga agaggcggtt
     4921 ttattagcca tggatccaga aaaggatgtg gatggtttcc atcccctaaa catgggacgt
     4981 ctttggtctg gacatccagt catgattccc tcgacacctg caggaattat ggaaatgttt
     5041 catgaatatg ggattgactt ggaaggtaaa aatgcggtcg tcatcggtcg ttcaaatatc
     5101 gttggaaaac ctatggctca gcttcttttg gctaaaaatg cgacagtaac cttggcccac
     5161 tcacgaactc ataatcttgc caaggtggct gctaaagcag atattcttgt agtcgcaatc
     5221 ggccgcgcca agtttgtgac tgctgacttt gtcaaaccag gtgcggttgt cattgacgtt
     5281 gggatgaatc gagatgaaaa tgggaagctc tgtggagatg ttgattatga ggcagttgca
     5341 ccacttgcta gccatatcac gccagtccct ggaggtgtcg gtcctatgac cattaccatg
     5401 ctgatggagc aaacttatca agcagcactt cggacattgg atagaaaata agagaaacat
     5461 tcgattaata gagtgtattt tctatagcta tatctaaaat ggcagaaatg aatattaaat
     5521 tttagatata agattacaaa aggaggtctg cgtctccttt ttattgtata ataaaagtga
     5581 gaggaaaaaa ggatgaaagt gattaatcaa accttattag aaaaagttat tattgaacgt
     5641 tctcgttcaa gtcataaagg agattatggt cgtctgctgc tgcttggtgg tacttatcct
     5701 tatggaggtg ccatcatcat ggctgcttta gcagctgtaa aaagcggtgc aggattggtg
     5761 accgttggaa cggacaggga aaatatcccg gctctgcaca gccatttacc tgagcctatg
     5821 gccttttctc ttcaagacca gcaattgtta aaagagcaat tggagaaggc agaagttgtc
     5881 ttgctggggc ctggtttacg agacgatgct tctggagaaa atctagtaaa acaggtcttt
     5941 gttaatttaa gccaaaatca gattttgatt gtagacggag gtgccttgac cattcttgct
     6001 aggacaagtt tgtcatttcc ctcaagccag cttatcctaa ctcctcacca aaaagaatgg
     6061 gaaaaattat ctggaattac gattgaaaag caaaaggaag atgcaacggc tagtgttctg
     6121 acttccttcc ctcaaggaac aattttggtg gagaaaggcc cagctactcg tatttgggaa
     6181 gttggccaat ctgattatta ccagttacag gttggtggtc cttatcaggc gactggggga
     6241 atgggagata ctctggctgg gatgatcgca ggatttgtag gccaattccg acaagccagt
     6301 ctctacgagc gtgtggcagt agcgacccat cttcattcag ccatagccca agaactatct
     6361 caagaaaatt atgtggtctt accgacggaa atcagcaggt atcttcccaa aataatgaaa
     6421 attatttgtc aacaagagag ggtaagtaaa gataaacttg tttaaaatag acagataaat
     6481 ctacttcctt ctcttaattt atgattcttg aaatgcgcct gctttaaggc taaactagac
     6541 gtatcaaagt taagattttg tttttgtaac tggaaagaga tgaacaaatc aaatacataa
     6601 aagataaact catttttatt cgtttggtaa aaataaaatg catattttta aagaaagatt
     6661 gatgaaaaat gtagatttga tgtttttact tgaataaaaa gcggtttcat agtaaaataa
     6721 gaactgagaa tgatggaggt aaatcggtgg aaaatctgaa gaaaatggca ggtatcaagg
     6781 ctgctgagtt cgtgagcgat ggaatggtcg ttggacttgg aacaggctcg actgcctatt
     6841 attttgtcga agaaatcggt cgtcgtatca aggaagaagg attgcagatt acagctgtaa
     6901 caacttctag tgtgaccact aaacaggcag aaggccttaa tatcccgctc aagtctattg
     6961 accaagtaga ctttgtcgat gtgacggttg atggcgcgga tgaagtggat agtcagttta
     7021 atggaatcaa aggcggtggt ggtgcccttc tcatggaaaa ggtggtcgca acaccatcaa
     7081 aagaatacat ttgggtggtg gatgaaagca agctggtcga aaaactaggt gcttttaaat
     7141 tgccagtaga agtggttcag tatggtgcag agcaggtctt tcgtcatttt gaacgagctg
     7201 gctacaaacc aagtttccgt gaaaaagacg gccaacgttt tgtgacggat atgcagaatt
     7261 ttatcattga cctcgccttg gatgtcattg aaaatccaat tgcttttgga caagaattgg
     7321 accatgtcgt tggtgttgtg gagcatggtt tattcaacca aatggtggat aaggtaatcg
     7381 ttgctggacg agatggagtt cagatttcaa cttcaaaaaa aggaaaatag aagggggcat
     7441 aagatgtcta aatttaatcg tattcatttg gtggtactgg attctgtagg aatcggtgca
     7501 gcaccagatg ctaataactt tgtcaatgca ggggttccag atggagcttc tgacacactg
     7561 ggacacattt caaaaacagt tggtttgaat gtcccaaaca tggctaaaat aggtcttgga
     7621 aatattcctc gtgaaactcc tcttaagact gtagcagctg aaagcaatcc aactggatat
     7681 gcaacaaaat tagaggaagt atctcttggt aaggatacta tgactggaca ctgggaaatc
     7741 atgggactca acattactga gcctttcgat actttctgga acggattccc agaagaaatc
     7801 ctgacaaaaa tcgaagaatt ctcaggacgc aaggttattc gtgaagccaa caaaccttat
     7861 tcaggaacgg ctgttatcga tgattttgga ccacgtcaga tggaaactgg agagttgatt
     7921 atctatactt cagctgaccc tgttttgcag attgctgccc acgaagacat tattcctttg
     7981 gatgaattgt accgtatctg tgaatacgct cgttcgatta cccttgagcg tcctgccctt
     8041 cttggtcgca tcattgctcg cccttatgta ggtgaaccag gtaacttcac tcgtacggca
     8101 aaccgtcgtg acttggctgt atctccattt tccccaactg ttttggataa attgaatgag
     8161 gctggtatcg atacttatgc tgtgggtaaa atcaacgata tctttaacgg tgctggtatc
     8221 aaccatgaca tgggtcacaa caagtcaaat agtcatggaa ttgatacact attgaagact
     8281 atgggacttg ctgagtttga aaaaggattc tcattcacaa acctagttga ctttgatgcc
     8341 ctttacggcc atcgtcgtaa tgctcacggt taccgtgatt gcttgcatga gtttgatgaa
     8401 cgcttacctg aaattatcgc agctatgaga gagaatgacc ttctcttgat tactgcggac
     8461 catggaaatg acccaacgta tgcaggaacg gatcacactc gggaatatat tccattgttg
     8521 gcctatagcc ctgcctttaa aggaaatggt ctcattccag taggacattt tgcagatatt
     8581 tcagcgactg ttgccgataa ctttggtgtg gaaactgcta tgattgggga aagtttctta
     8641 gataaattgg tataagatga cgcgctattc tttgctggtg agaggtatca atgttggtgg
     8701 taagaataag gtcgtcatgg cggagcttcg tcaagaattg acaaacttgg gactggaaaa
     8761 ggttgagagc tacatcaaca gtggcaatat tttctttact tcgatagatt ccaaagccca
     8821 attggttgaa aagctagaga ctttctttgc agtccattat ccatttattc agagcttttc
     8881 tttactgagc ctagaggact ttgaggcgga acttgaaaat ctaccagctt ggtggagcag
     8941 agacttggca cgaaaagatt ttctctttta cactgagggt ttggatgtgg accaagtcat
     9001 cgcgacagtt gaaagtttag agctgaaaga tgaagtgctt tattttggaa aacttgggat
     9061 tttctggggg aaattttctg aagaatccta ttctaagact gcctatcata agtacttgct
     9121 gaaggtgcct ttctaccgcc acattactat tcgtaatgct aaaacctttg acaaaattgg
     9181 tcaaatgcta aaaaaataat aaaggagaca cacaatgaca tttttaaaca aaatccatga
     9241 aactgctact ttcctgaaag aaaagggaat tgcagcccct gagttcggtc taatccttgg
     9301 atcaggactt ggagaattgg cagaagaaat cgaaaatcca gttgtagtag actatgctga
     9361 gattccaaac tggggccgtt caacagtagt cggtcatgct ggtaaattgg tatatggtga
     9421 actggcaggt cgcaaggtct tggctcttca agggcgtttc catttctatg aagggaatcc
     9481 tctggaagtg gtgactttcc cagttcgtgt gatgaaagtt cttggatgtg aaggtgttat
     9541 tgtaaccaat gcagctggcg gtatcggatt tggtcctggt accttgatgg ctatctcaga
     9601 ccatatcaac atgacggggc aaaatccatt gatgggtgaa aacttggatg actttggccc
     9661 acgtttccca gatatgtcta gggcttacac accagaatac cgtgccactg cccatgaagt
     9721 ggctaaaaaa cttaatatca agcttgatga aggtgtctat atcggagtta ctggtccgac
     9781 ttatgaaaca ccagcagaaa ttcgttccta taagacactg ggagcagatg cagttggtat
     9841 gtctacggtt cctgaagtta tcgtggcagc ccactctggc ttgaaagttc tgggaatttc
     9901 atgtatcact aactttgcgg ccggtttcca agaagaactc aatcacgaag aagttgtaga
     9961 agtgactgaa cgtgttaaag gtggtttcaa aggcttgctt aaagcgattc ttgctgaatt
    10021 gtaagaaaaa agatttaaaa gggggagtgc ctctgtcttt tcaggattga ctgcctatcc
    10081 gtattaaaga agaaacagag gaatactatg agcttcttcc tgctcttata actgaaagaa
    10141 gcggaagaat aggtatgtct gatctgatag ccagcattgt gaaagacaag attctaggat
    10201 actagcatta gcttcctagc caagcagact agtatgataa ggagagatga gaatgaattg
    10261 actttctgaa tttctcagtc ttatcatata tagcacaatg agatttcgct tgagtctgct
    10321 tgtaaataaa cgaaaagaaa gataagaaat aatgaaaatt ggtcaacgaa ttatgcgctt
    10381 tggcataaaa aattaagtat cggagttgta tctgttgtag tcggctttga tttctagctc
    10441 cagctggaat ttcagccaat gaagtaaagc aagatgtaac atctgaagtg gtaataggtg
    10501 tgctagattc taaggaggaa ttgaaagagt cagaaaatga tgctccaaaa ctagaaactc
    10561 ctcttagaga ggagccaaga ctagctcctc aaacgcttcc ggaagcaagt gaagttcttg
    10621 aaaacaaaag ggaagagtca aaagtagaga taacagagcc agctcaagcg gatgatatcc
    10681 gcaaggttgt tggggaatta gccaaggata taagtattac taagttgtat atgacaggtc
    10741 attctcttgg aggctaccta gctcagattg cagcggttga agattaccaa aaatatcctg
    10801 atttttataa ccatgtattg aggaaagtga caactttcag tgctcctaaa gtgattactt
    10861 ccagaactgt ttgggatgct aagaatggtt tctgagatgt tggtttggaa agtcgtaaat
    10921 tagctgttag tggaaaaatt aagcattatg tggttgataa tgacaatgtt gtgactccct
    10981 tgattcataa taatcgtgat attgttacat ttacaggtaa ttcacgcttt aaacaccgtt
    11041 ctcgtggcta ttttgaaagt ccaatgaatg atattcctaa ctttaatatt ggtaaacaag
    11101 ctaccttgga taaacatggt tatcgtgatc cgaaattgga taaagtgcga ttctttaaga
    11161 aacaggctct acctcaatct tctagtcaac caagcgctga accaatggaa aatattgcct
    11221 taggaaaaca ggttactcaa agttcgacag ctttcggagg agatgctaga agagctgtgg
    11281 atggcaaagt cgatggtaac tatggtcaca attctgtcac tcatacaaac ttccaatcta
    11341 agccttggtg gcaagtagat ttggctaaag aagaaaccat tcgccaaatc aatatttaca
    11401 accgaacaga cactgcccag gatagattgg caaactttga tgtcattctt ttagacagtt
    11461 ctggtaaaga aattgagtga aaacgtataa tatctcctaa agatgtgtca gcacaaatta
    11521 cgattaacca taaaaaacgc gctatgttcg gattgagcta gaaggctata atgccctcag
    11581 tcttgcagaa gttgaagttt tccgctttat agctacgaat gctgaaacgg cgacacaagt
    11641 ttctaagcca gttcaaccaa tcagtcagac tcctgtgaaa gataaaacat tgacaattca
    11701 acacagtgga gcttacattg cccgctactc cataacttgg gaagaagttc cagtagataa
    11761 agatggaaac caagttgttc gtagtcattc ttgggaagga aacggttgca accagactgc
    11821 aggttttgtc ctcaacctcc caatcaaaga aaatatgaga aatctgcgag ttaagattga
    11881 gaaaaagacg ggcctactat ggaatagatg gcaaacaatc tatgaaaaca gaccaatttt
    11941 agctcaaccc caccgtaaaa ttacccattg gggtacgaca ttgaattcca aggtgagtga
    12001 cgatgatgtc ttgtaatctg atggtacaat gacagttagt ttgtctagtt tataagaaag
    12061 tactacctga gcttgaatag aactcaggta gctctctgtg aaagaacaaa attaatactc
    12121 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaagc actgctttga
    12181 ggttgtagat aagactgacg aagtcagtca catatataat ccaaggcgac gttgacgtgg
    12241 tttgaagaga ttttcgaaga gtataaacag aaaggtagag cgcgtgttct aatttgaaca
    12301 cgagtagaaa acttttctaa aaacaaaaac gaaaggatgg gtaaactgta ttcgctgaac
    12361 tgaatacggg cgactctcct ctaaatcaaa attaagaaag aaaggaattg accccaccct
    12421 aaaagcagtg ggaaaaagat agttggtcta gcgagcatcg ctcactgcgc ccaactccta
    12481 ttttcccttc gctttttgac gggtttggta tctttctcaa tataaaatat aaaataaaga
    12541 aaggtagagc gtgtgttttg atttgaacac gagcggaaaa ctcggaaaat agataatctg
    12601 actgaaaaat caggatttct cgtcggcttc ctaattttca gtcgttttct tctcgctctt
    12661 tgtatcataa attatgtcta tccatattgc tgctcagcag ggtgaaattg ctgataaaat
    12721 tcttcttcct ggggatcctc ttcgtgctaa gtttattgcg gagaatttcc ttggtgatgc
    12781 tgtttgtttt aacgaagtgc gtaacatgtt tggttacact ggtacttaca agggtcaccg
    12841 tgtatctgtc atgggaactg ggatgggaat gccatctatt tcgatttatg cgcgtgagtt
    12901 aatcgtagac tacggtgtga agaaattgat tcgtgtggga actgcaggtt ctttgaatga
    12961 agaggttcat gttcgtgaat tagttttggc gcaggcggct gcaaccaact caaacatcgt
    13021 tcgtaatgac tggccacagt acgattttcc acaaattgct agctttgatt tgcttgataa
    13081 agcctaccat atcgccaaag aacttggtat gactactcac gttgggaacg ttttgtcatc
    13141 tgatgtcttt tactcaaatt actttgaaaa gaatatcgag cttggtaaat ggggagtcaa
    13201 ggctgtggaa atggaagcag cagctcttta ctatcttgct gcccaatacc atgttgatgc
    13261 gctagctatc atgaccatct ctgatagctt ggtcaatcca gacgaagaca caactgcaga
    13321 agaacgtcaa aataccttca ctgatatgat gaaggttggt ttggaaacct tgattgcaga
    13381 ataattatag ccaaaaagga agccctttat gaattgtagg acttcctttt cttatccaga
    13441 aattgatcta gctctctctg atttcgaaga atagtgactt tatgtgaata ttcttggcaa
    13501 agtttttggt aattttcttt ttgagttttg ctacgtccat cccaaagaat ccatctgata
    13561 aactcccagt caaagcgttc agggcaatct gccgccatac tttctctgac ttttccacgg
    13621 tatttaagat aacgcttaaa gggctctata atatttgtag tgggtaaatc ccttatagat
    13681 attatggagc ctatttttgt gta
//
LOCUS       DAVLZG010000055        13470 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLZG010000055 DAVLZG010000000
VERSION     DAVLZG010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.055"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..965)
                     /locus_tag="VYO72_001653"
     CDS             complement(<1..965)
                     /locus_tag="VYO72_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1707986.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNS"
     gene            1121..1536
                     /locus_tag="VYO72_001654"
                     /pseudo
     CDS             1121..1536
                     /locus_tag="VYO72_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1662..1928
                     /locus_tag="VYO72_001655"
     CDS             1662..1928
                     /locus_tag="VYO72_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707987.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            2189..4438
                     /gene="metE"
                     /locus_tag="VYO72_001656"
     CDS             2189..4438
                     /gene="metE"
                     /locus_tag="VYO72_001656"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1707988.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            4502..5368
                     /gene="metF"
                     /locus_tag="VYO72_001657"
     CDS             4502..5368
                     /gene="metF"
                     /locus_tag="VYO72_001657"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1707989.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            5927..8140
                     /gene="pnp"
                     /locus_tag="VYO72_001658"
     CDS             5927..8140
                     /gene="pnp"
                     /locus_tag="VYO72_001658"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1707990.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDYKPKKEFTETPKDSE"
     gene            8156..8773
                     /gene="cysE"
                     /locus_tag="VYO72_001659"
     CDS             8156..8773
                     /gene="cysE"
                     /locus_tag="VYO72_001659"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1707991.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            8785..9669
                     /locus_tag="VYO72_001660"
     CDS             8785..9669
                     /locus_tag="VYO72_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1707992.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            9751..11094
                     /locus_tag="VYO72_001661"
     CDS             9751..11094
                     /locus_tag="VYO72_001661"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1707993.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            11087..11473
                     /locus_tag="VYO72_001662"
     CDS             11087..11473
                     /locus_tag="VYO72_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1707994.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            11477..12361
                     /locus_tag="VYO72_001663"
     CDS             11477..12361
                     /locus_tag="VYO72_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1707995.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            12498..12953
                     /locus_tag="VYO72_001664"
     CDS             12498..12953
                     /locus_tag="VYO72_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707996.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            12950..13096
                     /locus_tag="VYO72_001665"
     CDS             12950..13096
                     /locus_tag="VYO72_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707997.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            13239..13409
                     /locus_tag="VYO72_001666"
                     /pseudo
     CDS             13239..13409
                     /locus_tag="VYO72_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         4123 a         2560 c         2999 g         3788 t
ORIGIN      
        1 gagttttgaa aacttacaat gtctaaatct ttaacatagt agtggttttt aggcaataaa
       61 atatgatcta ttgttgcatt aaaaagtttt ggactttggc tattccaagt tcctctttca
      121 aaaggtggca gtgcatttaa tgcgtcccta tgagagctta tttttgcaag tgctccatga
      181 cgcatagttg cattaaaatc acctgcaata atagcctttg gatattttga agccaattga
      241 ttatgaatga tgtttaagtc ttgcttccag atttccatta aacctggcag aggaggagca
      301 gtatgcaagg caatgatatc tggtatattt tgttttctcg aatgtaatac aattgtcccg
      361 aaccgtgttg tatgaaaagt tttagcttct gtatagaaac cataactttt cttgacaatc
      421 acagtcacag gagctattcc actattggta ggtggagaag tgaaaatatc atagttggcc
      481 atagaaagtc caacttgatg aaacaatagt ttgattctct ggttttcttg ctcacctctg
      541 atattggtag ctagttcagg gaatatagcc atatcggcgt caaaatggct aaaaattcgc
      601 tcaatatgtt gtgcttctat ttgattagcg acgttccaag ttactaattt taaggtttta
      661 gtcttatttg atgcagaaga aagggtttta tctgttccga ataatagtaa tatgagcgat
      721 agtaagagca aaatgccaga gtaaaaccgt atttgtttat ttttcttgta aaaagatagg
      781 aaaaaaaata agaaacttaa aatagcagcc atagttgcag tagctaaggg gaaggcataa
      841 atctgtgcca agataggttg ggtagatagc caaatgttaa gattagaaga tgggaaaaaa
      901 gaataagtta tgatagggat agaaaagaga atgaccgaaa gggcagagag aaatgtttta
      961 atcattgtgt gagtacctca atttgcaatg gttgctcgga gctaatgtga ctttgtgact
     1021 ttacttgatt gatattcttt ttcttgtctt cctcatagat taagtacaac ccaagtaaaa
     1081 aaagtccaat ttaagattga aatgattaaa aggcacagaa atgcaagaca attatactac
     1141 aaaaggcaaa catttgacaa tcgatagccg tcgcttaatc gaacgatgga aaaaagaagg
     1201 aaaatcaaat agagaaattg cctctctact tggaaaagct cctcaaacta tccacactga
     1261 aatcaagcgt gggacagtcc gacaatgtct tggaaaaggg cgcttcaaag agatttattc
     1321 tgccgactac gctcaacagt cttaagaaac taaaggaaaa gattctccac tatacataac
     1381 caaaaacata accaaaaatt ttcgcctgaa atgatggtga tggctaaagg ggttaacgtg
     1441 ggaatttcaa ccatttacta ttggattcat cgtggaaaat tggggttaag caagcaggaa
     1501 ctgctttatc ctagaaaagg aaaatcgctt aagaaatagg ctagcaccaa ctttaaaccc
     1561 actggtcaat ctatcgaatc ataattcgct cattttttta aaaatacata gacgtaaaaa
     1621 aaagagggtt aagtgatgaa gaatagtgct attgggagta attggaagga tgtccatctg
     1681 agctctttag caaggaggaa atccttgaaa gtgatatgcg agtggctatc atgagcgagt
     1741 tgattgaggc taggtatgaa caaggaatca gtcagaaaaa gctggaagaa gtcagtggaa
     1801 taagccagcc tgtcatagct aggatggaga caggaaagac tagtcctcag ttggatacag
     1861 tcttaaaagt cctagccagt ttaggaaaga cactagcaat cgtcccactt gaacagggaa
     1921 aaagttgact agaatcagtt atagtctttt ctaataacag gtcatagtca cttataagaa
     1981 ttactaataa catgttttag tattctaatt ggaatatagc tgtaaagtaa gaattacaaa
     2041 ggatttgaga cgtttgcttc aagtcttttt cttttgtccg aaacagatat atagtttcaa
     2101 actatatcaa accctaattt tttacaatta tacagacgct ttcttttctg ttaagatagt
     2161 ttcaacaaca aattttggag gacacatcat gtcaactaca atcatcggtt tccctcgttt
     2221 gggcgaattc cgtgaattaa aatttacaac tgaaaaatac tttagaaaag aaatctcaga
     2281 agaagaactt ttagcagcag caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga
     2341 aaaaggcatc actgaaattc catcaaatga cttttctcac tatgataact tcctagatgc
     2401 ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga
     2461 gcgctacttc gctttgggac gtggttacca gggagaaaaa ggggacgttc gcgcccttcc
     2521 aatgaagaaa tggttcaaca ctaactacca ctacatcgtt cctaaatttg aaaaagacac
     2581 tcaagtaaaa ttggctggtc acaagatttt cgatgagttc caagaagcca aagaacttgg
     2641 attgaacact cgtcctgttc ttgtaggtcc cttcactttc cttcaattgt cagactttga
     2701 agaaggcgtg aaagcagacg acttcgtaga tagcttagtg gctgcttacc aagaagtttt
     2761 tgctaaattg gctgaacttg gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa
     2821 agacttgaca gctgaagaaa aagctctctt cttgaacctt tacaacaaac tcttggctga
     2881 caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc
     2941 tgaccttgta aacttaccag tagatgctat cggtcttgac tttgttgaag gtaagaaaac
     3001 tcttgaactc gttaaaggtg gcttcccagc tgacaagact ctctatgtag gtattgtcaa
     3061 tggtaaaaac atctggcgca acaactacga aaagagcttg gctgttcttg agcaaattcc
     3121 agctgaaaac atcgttttga caagctcttg ctcacttctt catgtgccat ttacaactgc
     3181 taatgaagaa tttgaaccag cactcttgaa ccactttgcc tttgcagttg aaaaattgga
     3241 tgaaatccgt gacttggatg ctatccgaaa tggtcaaggt tcagaagctc ttgcagccaa
     3301 caaagaactc tttgcgactg agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc
     3361 tggcttgaca gacgcagact acactcgttt gccagccttt gcagaacgtg aagctatcca
     3421 agaagaagct ttcaaacttc cagctcttcc aacaacaacg attggttcat tccctcaaac
     3481 aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt gaattgtctc aaaaagagta
     3541 cgacgctttc cttgctgaaa cgattgacga atggatcaag tggcaagaag atattgactt
     3601 tgatgtcctt gttcacggtg aatttgagcg taatgacatg gttgagtact tcggtcaaaa
     3661 cttgtcagga tacctcttct ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt
     3721 aaaaccacca atcatctggg gtgatgtcac tcgtcttaac cctatcactg ttaaatggtc
     3781 tagctatgca caaagtcgta caaacaaacc tgttaaaggt atgttgactg gacctgttac
     3841 catccttaac tggtcattcc cacgtgaaga catctctatc aaggattcaa ctctccaaat
     3901 cgcccttgct atcaaggatg aagtacttga ccttgaagct gctggtgtga aaatcatcca
     3961 aatcgacgag gctgctcttc gtgaaaaatt gccactccgc cgtagcgact ggtacgaaga
     4021 ctaccttgac tgggctattc ctgccttccg cttggtacac tcaacagtag cgccagacac
     4081 acaaatccac actcacatgt gttactcaga atttacagat atcatcccag ctatcgataa
     4141 catggatgca gacgttattt cctttgaagc taaccgttca aaccttgaaa tcttggacga
     4201 actcaaagcg aaaaacttcc aaacagaagt gggacctggg gtttacgata tccactcacc
     4261 tcgtgtacca aatgaaggcg aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc
     4321 aagcaagaaa gtttggatca accctgactg tggtttgaaa acacgtggta tcccagaaac
     4381 aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga
     4441 ttggatttct ctccatacag tggttgttca aaaagaaatc aactagaaaa ggttattaca
     4501 tatgtcacgc caaacaccgt cactctcatt tgaagtgttc cctccaaacc cagccgtggg
     4561 taatgataac attatttcag ccttgcagga tatgcaggag ttggctcccc attttatcag
     4621 tgtaactgcc agcaataata aatttaatat caaggaaacg acggttcgtt tggctgactt
     4681 tatccaaaat gatttggcga ttccgaccat tgcccacttg ccagctattt atctaactaa
     4741 ggacaaggtt gctgaaacta ttgctgactt ggacaaagtt ggggtgcaga aaatcttggc
     4801 tcttcgtggg gatattattc cagacgtgga accacaaaag gatttccgct atgcaaccga
     4861 cttgattgag tttatcaagg aacaaacccc tcactttgat attattggag cttgctatcc
     4921 agaagggcat ccagattcgc caaatcagat ttcagatatt caaaatctta agaagaaagt
     4981 ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt gacaatgagc gcttctatga
     5041 ttttcaggac aagtgtatct tggctgggat tgatgttccc attcatgcag gaattatgcc
     5101 aattctgaat cgaaatcagg ctctccgact cttgaagact tgtgagaata tccatcttcc
     5161 acgcaaattt aaagccatct tagacaagta tgagcatgac cctgagtcgc tcagagcagc
     5221 aggacttgcc tatgcagtgg accaaatcgt ggacttggta actcaggatg ttgccggtgt
     5281 gcatctctat acgatgaata atgctgatac agcaaaatac atccatcaag caacccatgc
     5341 cttgtttaat caccagtctc taggataata aaagcaaacc attcttctca ggtgagggga
     5401 atggttcctt tttaatggta aagacctcac tttttaagaa aaatatgata aaatagattc
     5461 tgtacgtact tgatacaaag atgaaggtat taaataatac aatgcattta aactgtaaga
     5521 tttaacgaca cgagtgagtc aaatcgatgt tatttgacga aagagttagt aaagcattta
     5581 gctaatcgcc cgatagcgat tagcgtgaaa ggtttagata ctttaatatt aaacctttct
     5641 aatgatgtat cttgaaaact gaacacgcct acaactctgt ggaaaaagat aaatctgcct
     5701 aggagcagtc gctccgtcgt tcgatttcct attttccttt gagttgcttg acggcttagc
     5761 atcttgagta attgaacacg gccgaaaagc tgtgtaaaaa agataaactg tcttgtcttc
     5821 atcgaagact tcgtcagttt cctattttta ctttgctttt gacgtccttg gtatcttgat
     5881 ctttgtaggc aaggcgtata atttcatcaa tccaaagggg attaaaatgg caaaacaagt
     5941 gtttcaaacg acttttgcgg gtcgtgagtt aattgtagag actggtcagg ttgctaagca
     6001 agcaaatggc tctgttgtcg tacgttacgg tgagtcaact gtcttgactg ctgccgttat
     6061 gtctaagaaa atggcaactg gggatttttt cccactccaa gtcaactacg aagaaaaaat
     6121 gtatgcggct gggaagtttc ctggtggctt tatgaaacgt gaaggacgtc cttcaacaga
     6181 tgcgaccttg acagcgcgtt tgattgaccg tccgattcgt cctatgtttg cggaaggttt
     6241 ccgtaatgaa gtccaagtca tcaatacagt gctttcttat gatgaaaatg catctgcacc
     6301 aatggctgct atgtttggtt catctttggc actgtctatt tcagatattc catttgacgg
     6361 accaattgct ggggtacaag tgggatatgt agatggccaa atcatcatca acccaagtca
     6421 agaacaagca gagcaatctc ttcttgaatt gacagtagct ggaaccaagc acgctatcaa
     6481 catggtagag tctggtgcca aagaattgtc agaagaaatc atgttggaag cgcttcttaa
     6541 agggcacgaa gctgtcaaag aattgattgc cttccaagaa gaaatcgttg ctgctgtcgg
     6601 taaagaaaaa gcagaagtgg aattgcttca cgtggatgct gaattgcaag ctgaaatcat
     6661 tgcagcctac aacagtgacc tccaaaaggc agttcaagta gaagagaaat tggcccgtga
     6721 agctgcaact caagcagtga aagaccaagt gactgccgtt tacgaagaaa aatatgcgaa
     6781 ccacgaagaa tttgaccgta ttatgcgtga tgtggctgaa atcttggaac aaatggaaca
     6841 cgcagaagtg cgacgtttaa ttacagaaga caaggtgcgt cctgatggtc gtaaggtcga
     6901 tgaaatccgt cctttggatg cggttgttga cttccttcct cgtgtacatg gttcaggtct
     6961 ctttactcgt gggcaaactc aagctctttc agtcttgacc ttggctccga tgggagaaac
     7021 tcaaatcatt gatggtttgg atccagagta caagaaacgc tttatgcacc actataactt
     7081 ccctcaatat tctgtagggg aaacaggtcg ttacggtgcg ccaggtcgtc gtgaaatcgg
     7141 tcacggtgcc cttggtgagc gtgctcttgc tcaagtcttg ccaagcttgg aagaattccc
     7201 atacgctatc cgtctagtag cagaagtttt ggaatcaaac ggttcttcat ctcaagcttc
     7261 tatctgtgcg ggaactcttg cccttatggc tggtggtgtg ccaatcaagg cgccagtagc
     7321 tggtattgct atgggactta tctcagatgg aaataactac acagtattga cagatatcca
     7381 aggtttggaa gatcactttg gagatatgga cttcaaggtt gcaggtactc gtgatgggat
     7441 tacagccctt caaatggata tcaagattca agggattact gcagaaatct tgacggaggc
     7501 tcttgctcaa gccaagaaag cgcgttttga aatccttgat gtcattgaag caaccattcc
     7561 agaagttcgt ctagaattgg ctccaactgc tccgaaaatt gatacgatca agattgatgt
     7621 ggacaagatt aagattgtca tcggtaaggg tggagaaacc atcgacaaga ttatcgctga
     7681 aacaggtgtt aagattgata tagacgaaga aggaaatgtg tctatctact ctagtgacca
     7741 agatgctatt aaccgtgcca aagaaattat tgctggtttg gttcgtgaag ccaaagtgga
     7801 tgaagtttac cgtgctaaag tcgttcgtat cgagaaattt ggtgcctttg ttaacctctt
     7861 tgataagaca gatgcccttg ttcatatctc tgagatggct tggactcgta ccaatcgtgt
     7921 agaggatttg gtagaaatcg gggatgaagt tgatgttaag gttatcaaga ttgatgaaaa
     7981 aggccgtatc gatgcctcta tgaaggctct tctacctcgt ccgccaaaac ctgagcatga
     8041 tgaaaaaggt gaaaagtctg agcgccctca ccgcccacgt catcacaagg attacaaacc
     8101 taagaaagaa tttacagaaa caccaaaaga ttcagaataa gaaaaggaga aatgtatggg
     8161 gtggtggcgc gaaaccattg atattgtaaa agaaaatgat ccagcggccc gcaccacttt
     8221 ggaggttttg ctgacttatc caggtgtcaa ggccttggcg gcccaccgtc tctcgcattt
     8281 tctctggaag cacggcttca aactattagc tcgtatgtac agtcagtttt ggcgcttttg
     8341 gactcagatt gagattcatc caggagccca gattgattca ggtgttttta ttgaccatgg
     8401 ttctggtctg gtgattggag agacagcgat tgttgaaaaa ggcgttcttc tctatcacgg
     8461 agtgactctc gggggaacag ggaaagactg tggcaaacgc catccgactg tacgaaaggg
     8521 agccctcata tcagcccatg cccaagttat cgggcctgtg gaaattggtg aaaatgccaa
     8581 ggtcggtgct gcagcagttg tcgtagcaga tgtacctagt gacgtgacgg ttgtcggtat
     8641 tccggccaag attgtccgtc ttcatggtaa gaaagatgag cctgtcattc acgaagtcga
     8701 agaaaaacga gagtattatg tcaataaact cgagcaggct aaagatgcca gtcacagatc
     8761 gtctggtttg tagaggatac ctatatgatt caagcaagaa acaagttaag ccaagaggag
     8821 ctatctgagg cgaaaaaagt aattaactgt tgccaaaact atgacggtac ctatcgcgat
     8881 ccctatctct ctaacatgct taattttgac ccaaacatgc ccgccttttt cctttattat
     8941 gaaaaaggcg aacttgttgg tttattaact gtctatgcag atgaccaaga tgtagaagtg
     9001 acgatactgg ttcatccagg tcatcgccgt caggggattg cgcgtgcatt gtttactagt
     9061 tttgagagag aaacagcttc tttccccatt cggtcagtca cttttcagac agaacgtatt
     9121 tttttagaga atcatcctga ctttgccagt aactggggac taatcgagga tgaagagaca
     9181 gaaacttggt taggtaagga tagaagacct tatccgttag caaatgtttc ccatcttgaa
     9241 attttgttag cagatagttc gtatcaggat caaattagtc aattaaaatt tcaggcattt
     9301 tcagaggaac atgaatcgag agaagttgtg gatagatatg tcgctgaagc tctgaaagat
     9361 ccagaaagcc gactatatat tttattaaaa gctggtcagg ttattggaac ttgtacggtt
     9421 gatttatcga ctaatacgaa ttacctctac ggtttagcaa tattggaacc tgaacgtgga
     9481 aaaggctatg gaagctactt agcaaaatcc ctcgtcaacc aactaattga gcaaaatgac
     9541 aaggaatttc agattgcagt ggaagatagc aatgtaggtg ccaaacgttt gtatgaaaaa
     9601 attggctttg tcaaacagac tcaggtggtt tatctgaatg agaaaggagc aagggattcc
     9661 gaagtgtaga gatattcgga ctgaaattta cttgaacttt tagtgatgaa actaattgtt
     9721 cttggatttc agctttcctg attatgattt atgattaaaa tctatgacac catgtctcgt
     9781 gatttgcgag aatttgtccc gattgaggac ggcaagatca agatgtatgt ttgtgggcca
     9841 acggtgtaca actatatcca cgtgggaaac gcccgttcga cagtagcttt tgatacgatt
     9901 cgtcgctatt ttgagtaccg tgggtataag gttgcctata tttccaattt tacagatgtg
     9961 gatgataaga ttatcaaccg tgccagggaa gaaggcatca cgcctcagga ggttgcggat
    10021 aagtacatcg ctgcctttcg tgaggatgtg acggccttag gcgtgaaacc tgcgactcgc
    10081 catccgcgtg tagtggagtt tatggcagac atcatccgtt ttgtggaaga cttgatcgag
    10141 aaaggctttg cctatgagag tcaaggggat gtctatttcc gtgtagaaaa atcccacaac
    10201 tatgctaaat tggctaataa aaccttggaa gatttggatc taggtgcttc aggtcgtacc
    10261 gatgaagaaa cggctcgtaa ggaaaatcct gtagattttg ctctatggaa atcttccaaa
    10321 ccaggtgaga tttcttggga tagtccttgg ggacctggac gtccgggttg gcatattgag
    10381 tgttcagtca tgtcgacaga gattttaggt gataccattg atatccacgg tggtggagct
    10441 gacctagagt ttccacacca caccaatgaa attgcccaat ctgaagctaa aacaggcaag
    10501 gcttttgcta actactggat gcacaatggc tttgtcaata tcgacaatgt caaaatgtct
    10561 aagtccttgg gtaacttcat tacggtacac gatgccctta aaactcttga tgggcaagta
    10621 cttcgtttct tctttgcgac ccagcactac cgtaagccta tcaacttcac ggaaaaggca
    10681 gttcgcgatg ccgagaccaa tctcaagtat ctgaagaata cttacgaaca accatttaca
    10741 ggaaacgtgg atgcccaaga gttacaaaac tttaaagata agtttgtagc agctatggat
    10801 gaagatttta atgctgccaa cggtatcaca gttgtctttg aaatggccaa atggatcaac
    10861 tcagggaact atgatgcaag tgtcaagcaa gctcttgcag atatgttaga aatttttgga
    10921 attgtctttg ttgaggaagt tttggatgca gagattgaag acttgattca aaaacgccaa
    10981 gaggcgcgtg ccaatcgaga ctttgagaca gcagaccaaa tccgagacca actggctgct
    11041 caaggcatta aactattgga tacaaaagat ggagtgaggt ggacacgtga ttgatgtcaa
    11101 tctcattaac gggattgcgc tagcctttga gggggatgcg gtgtattcta tgtatattcg
    11161 ccgtcacctc atcctcaaag gtatgaccaa acccaataaa ctccatcaag aagcaaccaa
    11221 gtatgtgtca gccaaggctc aggctcgcct gattgctctc atgttggagg agcaggtcct
    11281 aacggaaaaa gaagaagaaa tctataaacg tggccgcaat accaatagcc acacaaaggc
    11341 taaaaatgca gatgtcgtga cttatcgtat gtccacggga tttgaagcgg ttatgggcta
    11401 tctccatatg actgagaatc tggaacgtct tgagagtttg gtttcatggt gcatccaaaa
    11461 agtggagggc tagaacatga gggcaaaaga actacaagac tggtttcctg aggctcggat
    11521 ttcagaccaa ccagtagaga aagagggcta tctcacgctc cctttagctt ctcagcagtg
    11581 gattttgctg gaggaagctg ggctcagcga gcgtgaaaag cagttggttg cccttttgac
    11641 ccagcaggag caggctcgtt cgctaaaccc ttggtattcc tatctggttg aaggcaaggg
    11701 acaggcaccg caagttttta aaaagattca gttggtttat tgccatcttt cttattttca
    11761 gcaggaaaat ctggcttctt ggctagatat gatgcggact ctttttccga attgtcagac
    11821 agtgctacag gtcggagctc aggattatgt tttcgtgctt caacaagaca aatacacttc
    11881 tgtaagagat attttaagtg atacgattga agcggttgag tatgactttg gacttcgtct
    11941 ttctatcatg ttgggtcagg tttggtctca gacaggacat caagccctat cagacttaat
    12001 caaagctgag cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac
    12061 tttttctcag ctctatcttt ggagtatggg agaaagactc gtggacttga agccaattaa
    12121 agaatgtcta caccagatga ttttggatca agatcagatt caggaaatca ttctctctct
    12181 ttgggaaaat agtgctgttc tcactaaaac agcccagcaa ctctatctgc accgcaattc
    12241 tctccaatac aagattgata aatgggaaga gttgacaggg cttcagttga aagagttgac
    12301 cgacctgacc ttgtgttatc aattgatttt aggttctttg tcaactatag ttggtttgta
    12361 aagaagttaa tatttggaga agaggattgc catcttctcc atttttatgt gcagagttat
    12421 agtggcttga tgctgggaaa gtacactgtg actgctaaaa cattcctaga agttgctttg
    12481 atttacctaa tctatttatg caaattttat gttattttac tataacagtt gttgctaagc
    12541 caaataatag tggggaagtt catttagacg taagcattga agataatcag ggaggtagtg
    12601 ggcataattt cagttctgtt tcaagtagct cacaaacagc taaatatgaa gaaactggtt
    12661 ataataacaa ttcatcatta tatataacga ttgataaaac gtctgatgca acagctcttt
    12721 tgaaattaaa gttgaataat gttgataatc aacctgctac tgaagttcct agttcaggaa
    12781 ttactgtaaa attaaatgct aaagataatg ctggaaactg gacaagtgct tcgaataaaa
    12841 aagaaataac agtaaaaatt gtttctgcta aaccgacata tccagacaaa atcttagtga
    12901 aaaatcctga taatataaaa gatacagaaa aaatgccatt attgaaaaat tgaaagaggc
    12961 aaataaaaat catccagcag gagctccaac ctttgctaaa ggtgaaggag agcatgcaaa
    13021 tgatattgta gcaacttatt cagatggtac aacttattat gtaccgttaa atgatgtgac
    13081 aaaatatgcg aggtagtggc tgtaccactc acttattcac ctccccgtga tttgtagtag
    13141 tgataggctt tctcactatt attataaaac aaaataaaga tcacaacact ttttcattct
    13201 gtgttgtgcc ttgagtgaaa cgaaaggaat gaattataaa tatgaaaagt atagtcacta
    13261 gcatagatga gcgcttgcgt actcgcctac gagtgattat ctggaagcaa tggaagaaga
    13321 aatcgagacg attatgggga ttgcttaagt taggggttcc taaatggata gcagataagg
    13381 tatctggctg gggcgaccac tatcaattat agtaaaatga aataagaata ggacgaatcg
    13441 ttcaggacag tcaaatcgat ttctaacaat
//
LOCUS       DAVLZG010000056        13035 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLZG010000056 DAVLZG010000000
VERSION     DAVLZG010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.056"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            24..860
                     /locus_tag="VYO72_001667"
     CDS             24..860
                     /locus_tag="VYO72_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1707998.1"
                     /translation="MKRKELRLSQQTLAEGICEQSQISKIERGHFIPSADLLFKLSQR
                     LEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERSTFLTLEDRT
                     YLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFYSLVGREQEY
                     EANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEALETIELCKQ
                     RQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMKIENYLKELD
                     TV"
     gene            1243..1863
                     /locus_tag="VYO72_001668"
     CDS             1243..1863
                     /locus_tag="VYO72_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1707999.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            1949..2392
                     /gene="tsaE"
                     /locus_tag="VYO72_001669"
     CDS             1949..2392
                     /gene="tsaE"
                     /locus_tag="VYO72_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1708000.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2382..2900
                     /locus_tag="VYO72_001670"
     CDS             2382..2900
                     /locus_tag="VYO72_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1708001.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2908..3924
                     /locus_tag="VYO72_001671"
     CDS             2908..3924
                     /locus_tag="VYO72_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1708002.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4009..5265
                     /locus_tag="VYO72_001672"
     CDS             4009..5265
                     /locus_tag="VYO72_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1708003.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5320..6486
                     /gene="recA"
                     /locus_tag="VYO72_001673"
     CDS             5320..6486
                     /gene="recA"
                     /locus_tag="VYO72_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1708004.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            6793..8163
                     /locus_tag="VYO72_001674"
     CDS             6793..8163
                     /locus_tag="VYO72_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1708005.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     YIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8539..9495
                     /gene="lytA"
                     /locus_tag="VYO72_001675"
     CDS             8539..9495
                     /gene="lytA"
                     /locus_tag="VYO72_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1708006.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9873..10034
                     /locus_tag="VYO72_001676"
     CDS             9873..10034
                     /locus_tag="VYO72_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1708007.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10021..10227
                     /locus_tag="VYO72_001677"
     CDS             10021..10227
                     /locus_tag="VYO72_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708008.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            10273..10626
                     /locus_tag="VYO72_001678"
     CDS             10273..10626
                     /locus_tag="VYO72_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708009.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKCY"
     gene            10760..11185
                     /locus_tag="VYO72_001679"
     CDS             10760..11185
                     /locus_tag="VYO72_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708010.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVKEFSLEYMTTGDILVEAFKA"
     gene            11593..12583
                     /locus_tag="VYO72_001680"
                     /pseudo
     CDS             11593..12583
                     /locus_tag="VYO72_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12573..>13035
                     /locus_tag="VYO72_001681"
     CDS             12573..>13035
                     /locus_tag="VYO72_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708011.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYSLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
BASE COUNT         4146 a         2068 c         2831 g         3990 t
ORIGIN      
        1 atacactcgc agagaaattc agattgaaaa gaaaagagtt gagactctcc caacaaactc
       61 ttgcagaagg aatttgtgaa caaagtcaga ttagtaaaat tgagagaggg catttcattc
      121 cctccgcaga ccttttgttc aaactctctc aacgacttga agtaccatta gattattttt
      181 ttaatgaaca aattgaaatt aaatctaacc tctctaattt caagcaattg tctgctcgac
      241 tattagacga tagaaattat gacgatttgg aatatattta tagaatagag attgaacgaa
      301 gtacttttct aacactagaa gaccgaactt atcttgaatg gattaaagct attattgact
      361 tttatcaata tgacagtaag tgtgaagcaa tttcttcatt ggaaaatata ttattaaaag
      421 tctcctcaaa tactctgatt tatttaaagg cgttgaatac tctatctaat ttctattcct
      481 tagtgggtcg tgaacaagaa tatgaggcaa actactctca tttaatagag ttgtatcaga
      541 caaaaaattt ggaccatcaa gagtttttat ttggctacat cagagttcgt tacaactacg
      601 ctcactacct agtatcaaag gaaaaatata atgaagccat ccaagaagct cttgagacga
      661 ttgaactctg taaacaaaga cagacaagct accaactggc tcctctactt attcttgtag
      721 gaaatgctgg agccaaattt ctagacagag aacaagtcaa aaattattat atagaagcaa
      781 aagagttatg taagatttat aacaatcctt taatgctgat gaagatagaa aattatttga
      841 aggaattaga tactgtttag ttaatcttga cattatagtt tttctgaaac gttaaataac
      901 ctgtaaggct gatagtgaaa tgaatactat cagccttatg attatgtgac tattagttcg
      961 tctcgctccg ttaggtgcga gacaaaaaaa acacccgcta gacggatttt catgatttca
     1021 aatttatatt cttcgaaaat ctcttcaaat cacgtcagct ctatctgcaa tctcaaaaca
     1081 gtgttttgag caacctgtgg ctagctacct agtttgatct ttgattttca ttgagtatta
     1141 gtctctagtg tttgtttagc gtcttaaaga gacatttgag aagattagaa acagttctct
     1201 cttttctcct agtataatga ttggtaggaa gggagagaga agatgaaatc aatgagaatc
     1261 ttatttttgt tagctttaat tcaaatcagt ttgagtagct gtttcctatg gaaggaatgc
     1321 atcttgtcct ttaaacaaag tacagctttt ttcatcggaa gcatggtttt cgtttcagga
     1381 atctgtgctg gagtaaatta tctttatacc cgtaagcaag aagtccatag tgtcctagcc
     1441 agtaagaagt cggtgaagct tttttacagt atgttactct taattaattt gttaggagct
     1501 gttcttgttt tgtcagataa cttgttcatc aaaaatacgc tgcagcaaga attagttgac
     1561 tttttattgc catccttctt tttcctattt gggctagatt tgctgatttt tttacccttg
     1621 aaaaaatacg tgcgcgattt tcttgctatg ctagacagaa aaaagacagt gttggtgact
     1681 attttagcaa cacttctttt cttaagaaat ccaatgacca ttgtctcact tctgatttat
     1741 attggactgg gcttgttttt tgcagcctat cttgtcccaa attcggttaa gaaggaagtt
     1801 tccttttatg gtcatatttt ccgagatctt gtattggtca ttgttacgct cattttcttt
     1861 tagagaaagc ctgtttttta tggatgttat gatgataagt ttagtaggaa aatagacaca
     1921 aaagaaaagt ttttggtata ataagagtat gtacacaaaa aatgaagaag agttgcaagc
     1981 cttaggggag cgtttgggcc atctattagc aaagaatgat gttttaatct taactggaga
     2041 actgggtgca ggtaaaacga cctttactaa aggacttgca aaaggattac agatttctca
     2101 aatgattaaa agtcccacct atactatcgt gagagagtat gaaggtcgac ttccacttta
     2161 tcacctagat gtttatcgta ttgaaggaga tgctgattct atcgacttgg atgagtttat
     2221 ctttggtggc ggcgtgactg ttattgagtg gggaaatctc ttaggagatg ccttgccaga
     2281 tgcttattta gaattggaaa ttctaaaaga agcagatgga cgccgtttaa attttcaggc
     2341 aaagggtttg cgtgctgaga aattgttaga ggagcttcaa tatggagtat gaattgctca
     2401 ttagggaagc agagcccaaa gatgcagctg aattagtggc ctttttaaat cgtgtgagtt
     2461 tggagacaga ctttaccagc ctagacggag atggtattct cttgactagt gaggagatgg
     2521 aaatattcct caacaagcaa gctagttcgg acaatcagat aaccttactt gcattcttaa
     2581 atggcaaaat tgctggtatt gtaaatatta cagctgatca gcgtaagaga gtccgtcata
     2641 ttggagatct cttcattgtg attggaaaaa gatattggaa taatggcttg ggaagtttgt
     2701 tgctagaaga agcgatagag tgggcacaag caggtggcat tctgcgtcgt ctccaactga
     2761 ctgtccaaac tcgtaatcaa gcagcagtcc atctttatca aaagcatggc tttgtcattg
     2821 aaggtagcca agagcgtggg gcatatatag aagaagggaa atttatcgat gtttacttga
     2881 tgggtaaact gataggttag tagaaatatg gttaaaaaaa ttattggaat ggtgctagct
     2941 ttactttctg taactgtagt aggagtaggt gtttttgctt atactattta tcaacaaggg
     3001 acagaaacct tagctaaaac ctataaaaaa atcggcgaag aaaccaaggt tattgaagcg
     3061 actgaacctc taaccattct gttaatggga gtggacaccg gaaatgctga acgaactgaa
     3121 acttgggtcg gtagaagtga tagcatgatc ttgatgacag tgaatcctaa aacgaaaaaa
     3181 acaacaatga tgagtttaga gcgggatatt ctgacgcgca ttgaatcagg gaatggtcag
     3241 gctcatgaag cgaaactgaa ctcagcatat gcagatggtg gagcagagct tgctatagaa
     3301 accattcaaa aaatgatgaa tatccatatt gatcgctatg taatggtcaa tatgagaggg
     3361 ttgcaaaaac tagtggatgc agtaggaggt attacagtca ataatatcct aggtttccca
     3421 atttctatca gtgaccaaga agaatttaat actatttcta tcggtgttgg ggagcaacat
     3481 attgggggag aagaagccct agtctatgca cgaatgcgtt accaagatcc tgagggggat
     3541 tatggtcgtc aaaaacgtca acgtgaagtt attcaaaaag tcatggaaaa agctctcagt
     3601 ttaaatagcg ttggtcatta tcaagagatt ctaaaagctt tgagtgacaa tatgcagacc
     3661 aatattgatt tgtctgcaaa aagtatccct aacttgctag gctataaaga ttcatttaaa
     3721 accattgaaa ctcagcagtt gcagggtgaa ggagagatac ttcaaggtgt ttcttaccag
     3781 attgtttcga gagcacatat gttggaaatg caaaatatac tccgacgttc tttgggacaa
     3841 gaagaagtta ctcagcttga aaccaatgcg gttttatttg aagatttatt tggcagagca
     3901 cctgttggtg atgaagataa ttaacttttg atacaaataa aaaaatcaat cgtaggaaaa
     3961 ttcctgcgat tttttcaaaa aaatacgaat agataggtag gaggaaacat gaaagcagaa
     4021 atcattgctg ttggaacaga gattttgaca ggacagattg tcaacaccaa tgcccagttt
     4081 ttgtcggaaa aactagctga gattggggta gatgtatatt ttcagacggc tgtaggagac
     4141 aatgaagttc gtctcttgtc tttgcttgag attgccagtc aacgtagcag tctggtgatt
     4201 ttgacaggcg gtttggggcc aactgaggac gacctaacca aacaaaccct agctaaattt
     4261 ttagggaaag cattagtctt tgatcctcag gctcaggaga agttggatat cttttttgcc
     4321 ctgcgaccag actatgcccg aacaccgaat aacgaaagac aagctcaaat tgtagaagga
     4381 gcgattccac tgccaaacga aacaggactg gctgttggag gaaaattaga agtagacgga
     4441 gtgacctatg tcgtccttcc aggtccgcca agtgaattga aacccatggt cttaaaccaa
     4501 cttctaccca agttgatgac agggagcaag ctgtattccc gagttcttcg tttctttggg
     4561 attggcgaga gccagttggt tacgattttg gctgatttaa ttgataatca gatcgatcct
     4621 accttggccc cttatgccaa gacaggagaa gtcactctac gtctgtcaac aaaggctagc
     4681 agtcaagaag aggcgaatca agcgctggat atcttggaaa atcaaatctt ggactgccag
     4741 actttcgaag gaatttcttt acgagacttt tgctatggtt atggggaaga aactagttta
     4801 gccagcattg tggtagaaga actgaaaagg caagggaaaa ccatcgcggc tgcagagagt
     4861 ttgacggcag gtcttttcca agctaccgtg gcgaattttt ctggagtttc aagtatattt
     4921 aagggtggtt ttgtgaccta tagcttggag gaaaaatcaa ggatgttgga tattcctgcc
     4981 aagaatttgg aagaacatgg tgtggtgtct gaatttacag ctcagaagat ggctgagcag
     5041 gcacgaagca agacccagtc tgattttgga attagtttga ccggagtggc aggaccagat
     5101 agcctagaag gacacccagt tgggacagtc ttcataggct tggcgcaaga gcaaggaact
     5161 gaggttatca aggttaatat tggaggcaga agccgagcag atgtacgtca tattgcggtt
     5221 atgcatgcct ttaacctagt tcgcaaggct ttattaagtg actaactttt gatataatag
     5281 tagataggtc tgaggatcat tagaatgtag gagaatagaa tggcgaaaaa accaaaaaaa
     5341 ttagaagaaa tttcaaaaaa atttggggca gaacgtgaaa aggccttgaa tgacgctctt
     5401 aaattgattg agaaagactt tggtaaagga tcaatcatgc gtttgggtga acgtgcggag
     5461 caaaaggtgc aagtgatgag ctcaggttct ttagctcttg acattgccct tggctcaggt
     5521 ggttatccta agggacgtat catcgaaatc tatggcccag agtcatctgg taagacaacg
     5581 gttgcccttc atgcagttgc acaagcgcaa aaagaaggtg ggattgctgc ctttatcgat
     5641 gcggaacatg cccttgatcc agcttatgct gcggcccttg gtgtcaatat tgacgaattg
     5701 ctcttgtctc aaccagactc aggagagcaa ggtcttgaga ttgcgggaaa attgattgac
     5761 tcaggtgcag ttgatcttgt cgtagtcgac tcagttgctg cccttgttcc tcgtgcggaa
     5821 attgatggag atatcggaga tagccatgtt ggtttgcagg ctcgtatgat gagccaggcc
     5881 atgcgtaaac ttggcgcctc tatcaataaa accaaaacaa ttgccatttt tatcaaccaa
     5941 ttgcgtgaaa aagttggagt gatgtttgga aatccagaaa caacaccggg cggacgtgct
     6001 ttgaaattct atgcttcagt ccgcttggat gttcgtggta atacacaaat taagggaact
     6061 ggtgaccaaa aagaaaccaa tgtcggtaaa gaaactaaga ttaaggttgt aaaaaataag
     6121 gtagctccac cgtttaagga agccgtagtt gaaattatgt acggagaagg aatttctaag
     6181 actggtgagc ttttgaagat tgcaagcgat ttggatatta tcaaaaaagc aggggcttgg
     6241 tattcttaca aagatgaaaa aattgggcaa ggttctgaga atgctaagaa atacttggca
     6301 gagcacccag aaatctttga tgaaattgat aagcaagtcc gttctaaatt tggcttgatt
     6361 gatggagaag aagtttcaga acaagatact gaaaacaaaa aagatgagcc aaagaaagaa
     6421 gaagcagtga atgaagaagt tccgcttgac ttaggcgatg aacttgaaat cgaaattgaa
     6481 gaataagctg ttaaagcagt ggagaaatcc gctacttttt cgatttttga ttcaagtttt
     6541 tagattatat atagtagatt gaaataagat atgaacaact ttattaggaa agtcaaatta
     6601 atttctagaa atgttttagc agctacagcg tactattcca aactcaacca actataatag
     6661 atcgaaacta gaatagtaca catctacttc taaaacattg ttaaaaatcg atttgactgt
     6721 ccttatttca ttccgctata tataagtttg ctgtttcttg tcgctcctct ggaaagctga
     6781 tataatagct ttatgaataa aaaacgaaca gtggacctga tacatggtcc gattcttccc
     6841 tcgctcttaa gcttcacctt tccaatcttg ttatcaaata tttttcaaca gctctataac
     6901 actgctgatg tcttgattgt tggacgattt cttggtcaag aatccttggc tgcagtagga
     6961 gcgacgacag cgatttttga tctgattgta ggttttacac ttggtgttgg caatggcatg
     7021 gggattgtca ttgctcgtta ttatggggct cggaatttca ctaaaatcaa ggaagcagta
     7081 gcagccacct ggattttagg tgctcttttg agcattctag ttatgttgct gggctttctt
     7141 ggcttgtatc ctctcttgca atacttagat actcctgcag aaattcttcc tcaatcttat
     7201 caatatattt ctatgattgt gacctgtgta ggtgtcagct ttgcttataa tctttttgca
     7261 ggcttgttgc ggtatattgg tgacagtcta gcagccctgg gatttctgat tttctctgcc
     7321 ttggttaatg tggttctgga tctctatttt attacgcaat tgcatctggg agttcaatcc
     7381 gcaggacttg ctaccattat ttcgcaaggt ttatcagcgg ttctctgctt ttattatatt
     7441 cgtaaaagtg tgccagaact cttgccacag tttaaacatt tcaaatggga caaaagcttg
     7501 tacgcggatc tcttggagca aggtttggct atgggcttga tgagttcaat tgtatctatc
     7561 ggcagtgtga ttttacagtt ttctgttaat acatttggtg cagtgattat tagtgcccag
     7621 acggcagctc gacgcattat gacctttgcc cttcttccta tgaccgctat ttctgcatca
     7681 atgacgacct ttgcttctca gaatctagga gctaagcgac ctgaccgcat tgttcaaggt
     7741 cttcgaatcg gcagtcgttt aagtatatcc tgggcagttt ttgtttgtat tttcctcttt
     7801 tttgccagtc cagccttggt ttccttcttg gctagttcga cagatggtta cttgatagaa
     7861 aatggaagtc tctatctgca aatcagttca gccttttatc ccattttgag cctcttgttg
     7921 atttatcgca attgcttgca gggcttgggg cagaagatcc ttcctctagt ttctagcttt
     7981 attgaactaa tcggaaaaat cgtttttgtg gttttgatta ttccttgggc aggatataag
     8041 ggtgttatcc tttgtgaacc tcttatctgg gttgccatga cagttcaact gtacttctca
     8101 ctattccgtc atcccttgat aaaagaagga aaggcaattt tggcaaccaa agtgcaatcc
     8161 tagttggatt tactgaataa aatccatttc ctctagtgaa catcgaaaaa acttgtgttc
     8221 tcttcttcag tttggtgttg aaaatagttt aacagacttt tgacttcttt tatatgatat
     8281 aataaagtat agtatttatg aaaaggacat atagagactg taaaaatata cttttgaaaa
     8341 gctttttagt ctggggtgtt attgtagata gaatgcagac cttgtcagtc ctatttacag
     8401 tgtcaaaata gtgcgttttg aggttctatc tacaagccta atcgtgacta agattgtctt
     8461 ctttgtaagg tagaaataaa ggagtttctg gttctggatt gtaaaaaatg agttgtttta
     8521 attgataagg agtagaatat ggaaattaat gtgagtaaat taagaacaga tttgcctcaa
     8581 gtcggcgtgc aaccatatag gcaagtacac gcacactcaa ctgggaatcc gcattcaacc
     8641 gtacagaatg aagcggatta tcactggcgg aaagacccag aattaggttt tttctcgcac
     8701 attgttggga acggttgcat catgcaggta ggacctgttg ataatggtgc ctgggacgtt
     8761 gggggcggtt ggaatgctga gacctatgca gcggttgaac tgattgaaag ccattcaact
     8821 aaagaagagt tcatgacgga ctaccgtctt tatatcgaac tcttacgcaa tctagcagat
     8881 gaagcaggtt tgccgaaaac gcttgataca gggagtttag ctggaattaa aacgcacgag
     8941 tattgcacga ataaccaacc aaacaaccac tcagaccatg tggatccata cccttacttg
     9001 gcaaaatggg gcattagccg tgagcagttt aagtatgata ttgagaacgg cttgacgatt
     9061 gaaacaggct ggcagaagaa tgacactggc tactggtacg tacattcaga cggctcttat
     9121 ccaaaagaca agtttgagaa aatcaatggc acttggtact actttgacag ttcaggctat
     9181 atgcttgcag accgctggag gaagcacaca gacggcaact ggtactggtt cgacaactca
     9241 ggtgaaatgg ctacaggctg gaagaaaatc gctgataagt ggtactattt caacgaagaa
     9301 ggtgccatga agacaggctg ggtcaagtac aaggacactt ggtactactt agacgctaaa
     9361 gaaggcgcca tggtatcaaa cgcctttatc cagtcagcgg acggaacagg ctggtactac
     9421 ctcaaaccag acggaacact ggcagacaag ccagaattca cagtagagcc agatggcttg
     9481 attacagtaa aataataatg gaatgtcttt caaatcagaa cagcgcatat tattaggtct
     9541 tgaaaaagct taatagtatg cgttttcttg tggagatatt tccttcaatt tttgctacta
     9601 tattaaacaa aaatcaaaaa gcaaactaga aagttatgct caaataaaat ctaaatttga
     9661 caatgtaaac cgagtcggat agctttaagt actgttttga ggttgaagat acgatttttg
     9721 ataggaactc atcaaatagg tttaatatca tcaattttag atttttaagt agcatcaata
     9781 aattgcttcc ttgttttgtc ataatttttt tatttaaaaa attatgacaa gagtgtgcta
     9841 ttctttttat gagaggtgta tgaatatgat aaatgtatgt gataaatgta tgtgatgttg
     9901 gaaaaagaat aaaagaactt agaatatctt caaatcttac tcaagataag attgctgagt
     9961 atttgtcttt gaatcaaagc atgattgcca aaatggaaaa aggtgaaagg aatatcacga
    10021 atggatttaa gtaataaagc tccaaatctt agaaaaaagt tgggagctga tggtgaatcg
    10081 ccgatagata tttttaaatt ggtacaaaag atagaaaatt tgacgctggt attttatgga
    10141 ctcggaaaga atattagcgg agtctgttat aaaggaactc agttcagtct cattgcagtc
    10201 aattcagaca tgtcattagg aaggtaaaga ttttctttag cacatgaact gtatcatctt
    10261 tattatgatg aggtgaagaa gagttcagtc agtcttatct tgattggtga aggagatgaa
    10321 actgaaagaa aagcggatca gtttgcttct tattttttaa ttttcccatc ttcactgtat
    10381 aggatggttg aggaaatcag agaaaatgcc aatagaactc atcttgaagt agaagatatt
    10441 ataaaattgg gtcagtttta tggtatcagt cataaagcta tgttatatag attgaggaat
    10501 gatggatacc ttgatgcaga agaaattaaa aatatggata ttagtgttat agagacagct
    10561 tcaagattag gctatgatac aagtttatat cgtcctttgt cagaaagtaa aaagaaatgt
    10621 tattaggata atatattaat ctaactgaac aacttttaga aaataacaga atttcgcaag
    10681 ggaagtatga ggaactgtta ctagatgctt tcagatatga tattgtatat gggctagatg
    10741 aagagggggg agttgtcgtt tgactagtcg tgtatttatt gatgcagatt gtatttcagt
    10801 atttttatgg gttggcactg aacatctttt agaaaagctc tatttgggta aaattgttat
    10861 tccacaagag gtgtatgatg aaatcaatat acctacaatt ccccatttaa aatctaggat
    10921 agatcagttg gtagctaagg gttcagctga gattgtgagc atagacattg gaactgaaga
    10981 atacgcatta tatagagatt taacaagaaa tcatgatagt aacaagatta ttggtaaggg
    11041 agaagcggct tctatttcct tagcgaaaaa gcataatggg atattaggaa gtaataacct
    11101 aagagatgtt aaatcatatg taaaagaatt ttctttagaa tatatgacaa caggagatat
    11161 actggttgaa gcgtttaaag cgtaatttat tactgaacaa gagggcaatc atatctggaa
    11221 taatatgctt aaaaagagaa ggaaaattgg tgcaaattca ttttcagact atcttcgtgg
    11281 aagtattcat caaaatagac aaaaataaat ttggataaat cgaactcact attcaggagg
    11341 catatgagca attcgaaaaa gaaaagtgtc aaattgagcc tataggagta gaagtgaaat
    11401 agtaagtcct gcatagtgga tgagagaaaa gttctccttg aagttttcct gaactatcag
    11461 tcgcatgtca aacgatatgt agggtaatgt gagaggggat agcgagtagt ttttggttat
    11521 tttatcaaaa aacttatatt ttattatacc gaatgataaa atataataaa aatgatagaa
    11581 taaggaaaaa acatgaatgt caaaaagata atgtcaattt ttcaatcctt ttatgttgat
    11641 gtcagtattg aggaactgac tttaccaatc agttttgtaa aaaagtttga gtatactcaa
    11701 atgacttttc ataaggaatc atttttattg attaaagaaa agagaagggg gagtttgagt
    11761 tcatttgtta ctcaggctcg cactatgggt gataaagcca atatggatgt tgttttggtg
    11821 ttttcgaagt tatcagacgg tgaaaaaaaa gcaattactt caagctagag ttccgtttgt
    11881 agactttaag ggaaacctct tcttccctac attgggacta gtactgaatg cgaatgatac
    11941 tgaagtccct aaggaattaa tacctagcga acaattaacg tggattgcct ttttattgac
    12001 aaaaggtcaa aaagtagtag atgttgattt gctttcacaa gtcactggac ttccaaactc
    12061 aacaatttat aggtgtttga ggacttttaa agctttatat ttgttaaaca agcaaaataa
    12121 gctttacaca tatacggtgt caaagaaaga attattctta aaatccgtgt catgtttatt
    12181 taatcccatc aaaaaacgga ttttattgcc agatggcgat ataaagcaga taaaatctgt
    12241 ttctaacctt ctatatggtg gtgcttatgc tttgtcgcat tcaacttttt tagctgaaac
    12301 ggatgaaaat attagctatg tcatatggca gagaaaattc aatcagttac ccttgccact
    12361 ttctcagcat attttaaaag gaaagatgct agagatatgg aaatatcgtc cttttgtatc
    12421 tgagttttgg aatgatttta aaaataatca tgataaacaa tttgtagatc cgatttctct
    12481 ttatttgacc ttaaaagatg atgatgaccc acgtatagag gaagagagtg aagcactaga
    12541 aaatatgata ttacagtatc tgggagaaga tgatgccagc taatacgaaa gttatttttc
    12601 aagaaacgtt tgcggatttt cagaactatt atgttctgat tgggggaact gctacctcta
    12661 tcgtattgga ttcgcaagga tttaaaagtc gcacaacaaa agattatgat atggtcatca
    12721 ttgatgaagt aaaaaataag gaattttata ctaccttgaa tcatttttta gaattgggag
    12781 agtatcaagg aagtcagaaa gatgagaaag cgcagctttt tcgatttaca acaactaatc
    12841 ctgagtttcc ttctatgatt gaactattta gtatcttacc agaatattca ttaaagaagg
    12901 acggtcgaga aattccctta cattttgacc aagatgctag tttatcagcc ttattattgg
    12961 atgaagatta ttataatata ttggtgcatg aaaaagaaac cattcagggg tattcggtat
    13021 tgagtaattg tggtc
//
LOCUS       DAVLZG010000057        12350 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLZG010000057 DAVLZG010000000
VERSION     DAVLZG010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12350
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.057"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..223
                     /locus_tag="VYO72_001682"
     CDS             <1..223
                     /locus_tag="VYO72_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1708012.1"
                     /translation="KNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKLPI
                     DSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            279..596
                     /locus_tag="VYO72_001683"
     CDS             279..596
                     /locus_tag="VYO72_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV1708013.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            906..2126
                     /locus_tag="VYO72_001684"
     CDS             906..2126
                     /locus_tag="VYO72_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV1708014.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDKSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKEKESIQKQIKKYK
                     DLSKNKDKTKEKGK"
     gene            2300..3022
                     /locus_tag="VYO72_001685"
     CDS             2300..3022
                     /locus_tag="VYO72_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1708015.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEKDIEIDKEREGEIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
     gene            3706..3867
                     /locus_tag="VYO72_001686"
     CDS             3706..3867
                     /locus_tag="VYO72_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708016.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQDMKNSFD
                     MAKTQIETD"
     gene            3959..5638
                     /locus_tag="VYO72_001687"
     CDS             3959..5638
                     /locus_tag="VYO72_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1708017.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIIEELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYKEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            5906..6472
                     /locus_tag="VYO72_001688"
     CDS             5906..6472
                     /locus_tag="VYO72_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708018.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            6794..6982
                     /locus_tag="VYO72_001689"
     CDS             6794..6982
                     /locus_tag="VYO72_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1708019.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            7043..7801
                     /locus_tag="VYO72_001690"
     CDS             7043..7801
                     /locus_tag="VYO72_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1708020.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDVRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            7859..8713
                     /locus_tag="VYO72_001691"
     CDS             7859..8713
                     /locus_tag="VYO72_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1708021.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEATYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            8825..9709
                     /locus_tag="VYO72_001692"
     CDS             8825..9709
                     /locus_tag="VYO72_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1708022.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            9872..10645
                     /locus_tag="VYO72_001693"
     CDS             9872..10645
                     /locus_tag="VYO72_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV1708023.1"
                     /translation="MELSAIYHGPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDGVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQ"
     gene            10712..11611
                     /locus_tag="VYO72_001694"
     CDS             10712..11611
                     /locus_tag="VYO72_001694"
                     /inference="COORDINATES: protein motif:HMM:NF012356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1708024.1"
                     /translation="MTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYW
                     IEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAV
                     MNYPLSDSIKDYFLRGIKNTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTA
                     NEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFM
                     KRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAV
                     VLASNCQELENQLVISPDGFVIF"
     gene            11886..12341
                     /locus_tag="VYO72_001695"
     CDS             11886..12341
                     /locus_tag="VYO72_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708025.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         4757 a         1674 c         2465 g         3454 t
ORIGIN      
        1 aaaaaataaa gaattgaata aagaagtagc attctattta acttcaatta ttaggcaagc
       61 tttaaaaaat actgaatata aagatcaaat atctagcaca gtattgccag atatcaaaat
      121 taaattaccg atagacagta gaggtactcc agattggaat tacatggaaa gatatataga
      181 agacttaaaa ttaaaatgca atatagcaaa ttataatatt taaaacaaga acgattagaa
      241 ataaaaatct agtcgttttt tattttaaga aaggatacat gatggcaagt aaaagattaa
      301 gtattgaaga acagattgaa aagaaagaag aaagcattaa gcaattacaa aatcaaaaaa
      361 gacagttgaa gaaaaaactt aatgaacaag aaagaaaagc aagaaacaaa agacttatag
      421 aaaaaggtgc agtgtttgaa agtatttttg aagaaagtat tgatttaaca aaagatgaat
      481 tttataagtt aataaaaacg ttaaatgatg aagaaataag attaaacata atggaaattt
      541 tagaagaaag aatagatgat aatgtagaaa aatcatctaa agatgaaata acataattgt
      601 cccttggtta caagggcgca attatacacc ctaaagggtg cttgcgtcct gcggagtcaa
      661 acccttgcag ggagcaacaa ccattcgctt tttaaaagtc aagggtaaat aaactcgcta
      721 aggctcgccc ttgactttta aaatttgaaa tgaaagtaac aattaagcca acatactgaa
      781 acaacaaaaa ttaattcagt agtcggcttt tttaattcta tcatttcaaa acgctcattc
      841 acaaagagga tataaaaaaa ctattaagcc tccacctaaa acaacaaaga aaggaagtga
      901 taaaaatggc agacagtttt catttttcag taaacataat atcaagagga aaaggcaaaa
      961 gtgcagtagc aagtgcagca tatataagtg gagaaaaaat aaaaaatgaa tgggacggag
     1021 taacccatga ctacacaaga aaagaaaaaa tattagtaaa aaatataata ttgcctgatc
     1081 atataccaaa agaatttaat gataagtcta ccttatggaa taaagtagaa atggcagaaa
     1141 aaaattctaa tgcacaacta gcaagacaat tcataatagg actaccaaaa gagttatctt
     1201 taagtgaaaa taaaaacctg gttgaaagat atataaaaga aaatttaaca tcacaaggaa
     1261 tgatagtaga ttatgcaatt catgatgaga gtcaagataa aaatggaaat atccattgtc
     1321 atataatgac cataatgcga ccaataaacg aaaaaggaga gttcttagcc aagtcaaaaa
     1381 aagaatatat cctagatgaa aaaggagaaa aagtattaaa caaaaatgga aaaccaaaga
     1441 caagaaaagt agaactaaca acctggaacg atacaggcaa tgtagaaaaa tggagagaaa
     1501 atttttcaga tctttgtaac aaatatttag aaagagcagg agcagaaaaa agagtagacc
     1561 ataggagttt taaaagacaa aattcagatt atctaccgac aatccattta ggatcagcag
     1621 caagtgcaat ggaaagaaag ggaatagaaa ctgacaaggg aaactataat agagaaataa
     1681 gaaaatataa tcaacttgta aaaacaataa aagaagagat aaaaacatta aagggttgga
     1741 taggaaattt attagataac ttatctactg cttatgaaaa atttaaggat atcgaaagag
     1801 ataaggtaat agacaaccct aaacttttta atctaacaaa ttatctatta acttattcag
     1861 aaattcaaaa agaaaaaagt aaatatctaa aaggatatgc aaaaactaat aaagaaaaat
     1921 atgacttcaa aaagctaaca agtgcatata gttatttaag aaaaaacaac atagaaacca
     1981 taggtcagtt acaaacaaaa atagaaactt taaagtctaa tagttatagg ctaaataaaa
     2041 aagaaaaaga aagtatccaa aaacaaataa agaaatacaa agacctatcc aaaaacaaag
     2101 ataagacaaa agaaaaagga aagtaaaaga aaaagtaaaa ccaaacaaaa aagatatgac
     2161 cagagaaatc taaagggagt aacgaaaagt tacaccctta aataaccata ataacaagac
     2221 ttccgaaaaa cagaagtcca gaattccgaa aatcggaaat caagaatttc gattatcgaa
     2281 aatcaagaaa ggagcagata tggcaacaaa caaaagatac tattggataa aattaaaaga
     2341 agaatttttc acagacaaaa ggataaaaag gttaaggaga atatctggag gagataccta
     2401 tacgataatc tacctaaaac ttctactact aagcctaaaa gatgagggca aactctatta
     2461 tgacggagta gaaagtgatt ttataaaaga gttagcacta accatagatg aaacagacga
     2521 tgatgtaatg gtaacagtaa attatttaat caatcaaggc ttattagaag ttgtaacaga
     2581 aaatgatgaa tactacctaa ctgaaatacc aaacttaatc ggatcagaaa cagcctgggc
     2641 agagaaaaaa agaagataca gacaaaataa acagaggaca ttgtccttaa tgagtccaac
     2701 ccatgtccga caagagatag agaaagatat agagatagat aaagagagag agggagagat
     2761 agataaaaag tccaccccca ttttttatgg agaattcaaa aatgtaaggt taagcaaaga
     2821 agaatataaa aatctaaaag aaaaattaaa ctcacacaca gatataatga taaataaact
     2881 atccagatac atggaaagca gtggtaagac ctatcaaaac cactatgtga caatattaaa
     2941 atggtatgaa gaagataaag acaaactaag acagaaaggt ttaaataaaa aaatgaatta
     3001 tgatgtagga gaatctttat agataaaaag aggtggaaag gcactattaa agactttaag
     3061 tctaaaaagg tatcaaagta tgccagagat aaaaaaatat aaatatgaca ctttaaaggc
     3121 gattagaaaa ttaaagaaat gctagaagac ttttagatga cagttaccaa gagggtctaa
     3181 ttttcactgc tacttatgca gtgggaattg aaccttttta tataagcaaa ttctatttca
     3241 aaattggtta ccaagaaaga cttcttttca ctgttaagta taagagggta atttatagaa
     3301 ttttgttaca tcaagataaa tattttctga tggtcaaatt ttaaaaagat taataactct
     3361 cgataaattt tgaaccttaa caattgaata gaccaagaca agacgttaat tattttttga
     3421 gcgtaataac ctatccgtca agatctttcg gctgaataat tcggcaaaaa aagttctgct
     3481 aagcaaaaag aaagtgagcg ataagtaaga gtttgaatat agggagggat accctatccg
     3541 ctatgaagaa aatgaggata atgatacttc taaggttgaa gccggctcat ccggaataga
     3601 ggcggaggtg agattcctat gttgctaatc caaagcactt gtcaatgtca aaaaacttaa
     3661 ttaaacaaat aattattaga tataaaactt tagaggaggt atatattgga caatgactgg
     3721 aatggattgg ctgatttaat agcaaatctg attgcaaaat atgctggtgc tttagattta
     3781 gataatctac ccgatccaac gccagcaaaa aatcaagata tgaaaaatag ttttgacatg
     3841 gcaaaaacac aaattgagac ggactaataa aagtgttata atatacttga aatgatagtc
     3901 caaacttaaa ttaaaaaaat tatatatgat atagaaaaat tatattgagg ttaatactat
     3961 gtcaaaagaa aaaataaaag tatacctcta tacacgagta tctacgtcaa tacagataga
     4021 ggggtattcg ttagaggcac aaaaatcacg aatgaaagct tttgctattt acaacgatta
     4081 tgaaattgtt ggagagtatg aagatgccgg gaagtctgac aagtctattg aaggtagaat
     4141 acagttcaat cgaatgatgg aagatataaa atctggaaaa gatggagtat cttttgttct
     4201 tgtgtttaag ttatcaagat ttgcaagaaa tgccgctgat gttctttcta cacttcagat
     4261 aatgcaggat tatggagtta atcttatctg cgttgaagat ggcattgatt catctaaaga
     4321 tgctgggaaa ctaatgattt ctgttttatc agctgtggct gaaatagaaa gagaaaacat
     4381 ccgtattcaa acaatggaag gtcgcattca aaaagcaagg gaaggaaaat ggaatggtgg
     4441 ctttgctccg tatggatata aacttgaaga cggcaagctg tttataaatg aggaagaggc
     4501 agttgcaata agaacgattt tcgaccagta tgtaaatact acgataggag ccaatgggat
     4561 atctaaatac ttagagaatc atggaattag aaaaatccca agacagaatg gtaagaatcc
     4621 tttgtttgat gcaggtctta taagaaagat attaaagaat cctgtatata atgggaaaat
     4681 agcatttgga agaagaactt tagaaaaagt tcatggtaca agaaatgaat ataagcaggt
     4741 tgaacaagat gaatatctaa tatctgaagg gatacatgaa gctatagttt ccgatgaagt
     4801 ttggcaagct gctcaggtta agctaaaatc tcaagcaaag aaatatgagc atgtgaataa
     4861 aggaaaagat acacgcacac acttgctttc tggaattgta aaatgcccga tatgtggagt
     4921 gggaatgttt gggaacaagt gtatcaagaa aaagaaagat ggcacaaagt ataaagattt
     4981 ttattactat ggttgtaaac ataggcagat gataagaggt cataagtgta cattcagtaa
     5041 gcaaattata gaagaattgt tagatgatgc tgttgcagag gtgattgtca agatagtaag
     5101 taatccgaaa tttgcttcta tgatgcaaga aaaaatcaac atgaaggtgg atacctctga
     5161 aatagaaaaa gaaatagata attaccaaaa ggaattgaga aagagtcatt ctacaaagtt
     5221 taagctaatt gaggaaatag ataatttaga tgttgaagat aagcattata agagaaggaa
     5281 acaggattta gatgatagac tatatcgtat gtatgacaaa atagatgaat tagaatcatc
     5341 actaattgat gcgaaagcaa agaaacagac tattgaagct gaaaagctta caggagataa
     5401 catatataag gttctgatct attttgataa gctctataaa gtcatgaatg atgtagagcg
     5461 taggcagtta atttcagctt tgatttctga aattcaagtt tataaagaaa aacaatctaa
     5521 cggacaatgg ctaaaatcca ttacttttaa gctaccaatt atagaagaaa atctcaacat
     5581 aggtttggac aatgatgaac aagttgaatg tgtaagttta ttagagaaac gtagttaatc
     5641 ctcaaaaggt tccccgaacc ttttgagtcc cactgacgca tcacgctgag gcggtatcac
     5701 tgcttgtacg agttgaagca tcagcaaagt aaaagtagat gttcagccaa tgcgacgagg
     5761 tgagaccgaa ggtcgataag gtgtgttctg ggtataggac tcgtaaagta agtaggaaat
     5821 atgatgagat gatacagaga gcctgaattg gtcaggtgac gtgcttattt acattagcct
     5881 gataatgaaa atggagagat tatcgatggt tatattggaa ttgtaccaaa atgattattc
     5941 taaagattta gtagcatttg attccataga agatgggaaa gcctttgtag ctcaaatccc
     6001 gggatacact ctggaaacag aagatggttt tgaagtggag tattttaatc ctaaaaacat
     6061 accggattat atggaaatta tttttaacgg aaatattgtt cctttatcta aatttatgtt
     6121 cgatcctggg gaaaatgtaa acattatttg gaaagagatt tcaaatttat ccctcaaaaa
     6181 tgatagagtg atcgaaggat attcaaaaat tgatgcatat gtcgttaaca accatgaagt
     6241 taaagcctat gtcgaaacaa gagaaacgaa ctatcgtaaa gcaaaagact tcttagaaag
     6301 ccgcggatat gaaatcgaca gaagcttttt cggaagtgaa gacggtgaag cgattcttta
     6361 cagaaaaaaa gggatcgaag tttggcattt cttgtgtcac ttagacccaa tgtttgtaga
     6421 gattgaagat gtagaaggat atgttaaaga agaagttgga gagattcaat agtcaaccaa
     6481 agttccttgt gagtatatac ctttgctagt aaaagagtca aaacgttata acgaaggggg
     6541 ggaagaaaat ccttgagtgt aagtcttttt cttgtttaga gggaaagtat tagagtagcc
     6601 gctcataatt tatactagat ttgataactg atttgagaca gattttattt ctataaatat
     6661 tgtgaaaatt ttttaatacc aaagatttaa agttactgtg taaaaaatcc tctccacttt
     6721 taaactaatg tattataaaa gccagttgac acaagtgtta cacctgtgat agaattaact
     6781 tgaggtgatg aaaatggcaa ccgataaaaa tagaataatg attagtttgg atgataaaaa
     6841 tctagagaaa cttgaaaatt tagtagaaga tgctagagat agaaggggaa tgcgactaac
     6901 aaagtcccag gttattgaat tactcctaaa taccgttgat tatttcgatg atattatggg
     6961 ggctatttac tcaaaaaaat aagagcaaaa ttgctattat ttttacaaat tggtgtaaca
     7021 ctagtgatat aggagtgatg aaatggttgt ttatattaga caaagtaaat taccaagtga
     7081 ggtttcaatt aataaataca atgctcaagt aggtgcctac ttacaaggag aagaagttat
     7141 tttatatcaa tctttttctg aaataaaaga gttaacaagt gaagatatag ttgtagatta
     7201 tataatggag actagagcat tactaaaaat gatgggctta aacgttccgg tttatgacta
     7261 tcctattgag cttaaagagt tttatggtcg aaagatttat gctggtattt taggagagat
     7321 tgtgaatata cctgataatt ggggaaaatt tattaagcct aaagctggtt caaaagtctt
     7381 tactggaaga gttgttaatg gaacccatga tttaataggt attggtctac ctttcgacta
     7441 tcctatatgg attagtgagg ttgtagaatt catagctgaa tggcgttgtt ttgtgttaga
     7501 tgttcgcgta ttagatgttc gaccctatac aggtgattat catgcacaat ttgatgcaag
     7561 tgtaattgat gaagcgatat catgttggaa agatgcgcca atagcttatg gactagatat
     7621 cggtgttact cgcgatggca gaacacttgt tgttgaagta aatgatggtt atgcattggg
     7681 aaattatggc ctatctcctt taaaatcaat caattttcat agagctaggt ggaaagaaat
     7741 ggtaaaaccc tattttgaaa aaaatgaaat ttttaaaatc caacaggatg ttattttcta
     7801 aaataaatat ggtagataac caatataaaa agcatcaaaa tgaacaagga ggaatctgat
     7861 gcttggagca attattggag atattgtcgg ttctgtttac gaatggaaca atatcaaaac
     7921 aaaggacttt cctttatttc ggaaggactg cttttttaca gatgacacgg ttatgacctg
     7981 tgctgttgca gaagcaatta tgaatggtgg acaaaaagac gatttcattg acgcgatgaa
     8041 gaaatatggc agaatgtatc cgaatgctga ttacggtgct cggtttaatg catggctaaa
     8101 cagcgataac cgtgaacctt ataatagctt tgggaatgga tcagctatgc gtatttctcc
     8161 atgtgcttgg atcatggact gtggttttta tgcgaaaact ggtatgtggc catcatctag
     8221 aggacttacg agtctttctg cagaggtaac tcataatcat ccagaaggtg tcaaaggcgc
     8281 tatggctaca gctgatgcta tctttctatg tcgtttttac tttggtggtt attgtagaga
     8341 gtacgagcaa tcaattaacg acaatcctac agagtgtaaa agacgaatta aggattatat
     8401 agaaaaagaa tacgattaca atctatctca aactttagat gaaatccgtc ctaactatcg
     8461 ttttaacgaa acatgtcagg aaactgtccc tcaagccatt atcgcctttc ttgaaagtag
     8521 agacttcgaa gatgcgataa gaaatgccat ctcacttggt ggcgacagtg atactctcgc
     8581 agcaatcact tgtagcatag cagaggcaac ttacggtatt cctgattgga tcaaggataa
     8641 ggcctattct tacttggatg aacccttaaa ggatgtagtt aggcgatggg aaaatagaat
     8701 aaaagcgtat taatctccag tacgtcagat ttctcttttc tgtattttca ttgtataata
     8761 ggattacatt tacttgcata cgacgaaatg taaacatttc tgtttaaaat taaggataaa
     8821 atcaatgaaa aaagcaatgg taattatcaa ccctacttct ggtggcgaga aggctttgga
     8881 ttacaaagaa aagctggaga ataaagcaaa agaatacttt gaatatgttg aaaccaaaat
     8941 taccgaaaaa gcgctggatg caacacattt tgctgaagaa gcttctcgtg agcagtatga
     9001 tgcagtggtt gtgtttggtg gagatggaac tgtcaatgaa gtcatttcag gtattgatga
     9061 gagagactac attcctaagt tagggattat cccaggcggt acgggtaacc tcattacaaa
     9121 acttttggaa atcaatcaag acatcgatgg cgcaattgac gaactggatt ttgatttaac
     9181 caataagatt gatatcggta aagcaaatga caactatttt ggttatatct ttagtatcgg
     9241 ttctctgcct gaggcgattc acaatgttga aatagaggac aaaacaaaat tcggtatttt
     9301 aacctatgct gtaaatacca tgaagtctgt catgacagat caggtcttta acattaaggt
     9361 tgagacagaa aatggaaatt atgttggtga agctagccat gttttggtcc ttttgacaaa
     9421 ttacttcgct gataagaaaa tctttgaaga aaacaaggac ggctatgcca acattttgat
     9481 tctgaaagat gcctctatat tctccaaatt atccgtcatt cctgatttat taaaagggga
     9541 tgttatcgca aatgataata tcgagtatat caaagcgcgt aatattaaaa tctcttcaga
     9601 tagtgaattg gagtcagatg ttgacggaga taaatcagat aacctacctg tagaaatcaa
     9661 agtcctagct cagcgagtag aagtattttc aaaaccgaaa gaggattagt atatagagaa
     9721 agcctttttt aaggcttttt gtatacttta aaagatagtt cctttaacaa cggacattcc
     9781 ttgcaaatag tttacaaaaa tagtatactg gatttattga gtttgaaaac gtttgcgtaa
     9841 aatttgaatg aatactttag gagacaaatt gatggaatta agtgctattt accatgggcc
     9901 tgagtcggag tatgcctatc tttataagga taagaaactc catattcgaa ttcgaactaa
     9961 gaaaggggac attgaaagca tcaacttgca ctatggggac ccttttatct ttatggagga
    10021 gttttatcag gatacaaaag aaatggtcaa gataacttct ggtaccttat ttgaccattg
    10081 gcaggttgaa gtgtcagttg actttgcacg tatccagtat ctctttgagc tcagagatac
    10141 agaaggtcaa aatattttgt atggcgataa agggtgtgtg gaaaattctc tagaaaatct
    10201 tcatgcaatt gggaatggat ttaagttgcc ttatcttcat gagattgatg cctgcaaggt
    10261 tcctgacggg gtttcaaata cggtatggta tcagatattt cctgaaagat ttgccaatgg
    10321 caatgctcta ttaaacccag aagggacttt agactgggat tcatctgtca cacctaagag
    10381 tgatgatttc tttggtggtg atttacaggg gattattgat catatggatt acttgcaaga
    10441 cttgggtatt actggactat atctttgtcc catctttgaa tctacaagca atcacaagta
    10501 caatacgaca gattactttg aaattgaccg tcattttgga gacaaggaga cctttcggga
    10561 actggtggat caagcgcatc atcgtggcat gaaagtcatg ctggatgcgg tatttaatca
    10621 tattggttcg caatctcttc aatgaaaaaa tgtcgtcaaa aatggtgaac agtctgctta
    10681 taaggattgg ttccatattc aacaattccc agtgacaact gaaaagctag ttaataagag
    10741 agacttaccc tatcatgttt ttggtttcga ggactatatg cctaagctaa atacagccaa
    10801 tccagaggtc aagaattatc ttttaaaggt tgcgacttat tggattgaag agtttaatat
    10861 cgatgcttgg cgtttggatg tggctaatga gattgaccat cagttctgga aggattttcg
    10921 taaggcagtt ttagctaaaa atcctgatct ttatatccta ggagaagtct ggcatacatc
    10981 tcagccttgg ctaaatggag atgagttcca tgccgtcatg aattatcctt tatctgatag
    11041 tatcaaggac tatttcttac gaggaattaa gaatacagac cagttcatcg atgaaatcaa
    11101 tggagagtct atgtattaca agcagcagat ttcagaggtc atgtttaatc tcttggattc
    11161 acatgataca gagcgaatcc tgtggacggc caatgaagat gttcaactgg ttaaatcagc
    11221 cttagccttt ctctttttac aaaaaggaac accgtgcatt tattacggaa ccgagctagc
    11281 cttgactgga ggaccagatc cagattgtcg tcgttgtatg ccttgggaac gtgtatcaag
    11341 tgacaatgat atgctgaact ttatgaagag gctgattaag attcggaaat acgcgtcagt
    11401 aatcatttcg catggcaagt atagccttca agaaatcaaa tctgatctag tagctctgga
    11461 atggaaatac gaaggacgga tcctcaaagc aatattcaac caatcaacag aagattatct
    11521 tttagagaaa gaagcagtag tactagcaag caattgccaa gaattggaga atcagcttgt
    11581 catctctcca gatggatttg tgattttcta aaaactagtt gatgaagatt atggtacatt
    11641 tcatatctta tatagtataa taaggctagt tactaaactt gtaaaggaga acttaaatga
    11701 attgtagagg acatgaaaca agacaaagaa ttgttagaga ttttgaagtt tagcctaaag
    11761 cacatattaa gctgttagca aatcaacaaa aacatagtga tgcaggagca actattgaag
    11821 atgaatatta tgtatttatc gctgagagta aaattgatgg caagaaggaa gttattcagt
    11881 gttgcatggg tgcggcaagg gattttttag aactaattaa tcacaaaggg ctacctcttt
    11941 ttaatccgct tgtaggtgat tctcatgtaa ataatagaca agaatatgac aatacaggga
    12001 gtggaaattt acaacctgaa aagtggaatg aaactgcaaa gcagctttat aatgttataa
    12061 tgtggttgat tattttatgg aatgctaagc cggatacacc tttatttaat tttaaagacg
    12121 aagtaattaa gtataaaaca tatgagcctt ttgaaagcag tataaaaaga gtaaatacta
    12181 ctataaagaa tggtagtaaa gggaaaactc tgactgagat gattaatggc tacagagcgg
    12241 ataacgatat tagagatgaa atttgtaact ttaatattct gaaaaataaa attcgtgata
    12301 tgaaagacca acaaggaaat acaatggaat cttactttta gttattgttg
//
LOCUS       DAVLZG010000058        11832 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLZG010000058 DAVLZG010000000
VERSION     DAVLZG010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11832
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.058"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            8..1009
                     /locus_tag="VYO72_001696"
     CDS             8..1009
                     /locus_tag="VYO72_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1708026.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1614..1691
                     /locus_tag="VYO72_001697"
                     /pseudo
     CDS             1614..1691
                     /locus_tag="VYO72_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2192..3553
                     /gene="trpE"
                     /locus_tag="VYO72_001698"
     CDS             2192..3553
                     /gene="trpE"
                     /locus_tag="VYO72_001698"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1708027.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3550..4116
                     /locus_tag="VYO72_001699"
     CDS             3550..4116
                     /locus_tag="VYO72_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1708028.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4127..5131
                     /gene="trpD"
                     /locus_tag="VYO72_001700"
     CDS             4127..5131
                     /gene="trpD"
                     /locus_tag="VYO72_001700"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1708029.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5128..5895
                     /gene="trpC"
                     /locus_tag="VYO72_001701"
     CDS             5128..5895
                     /gene="trpC"
                     /locus_tag="VYO72_001701"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1708030.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            5882..6481
                     /locus_tag="VYO72_001702"
     CDS             5882..6481
                     /locus_tag="VYO72_001702"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1708031.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            6459..7682
                     /gene="trpB"
                     /locus_tag="VYO72_001703"
     CDS             6459..7682
                     /gene="trpB"
                     /locus_tag="VYO72_001703"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1708032.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7675..8451
                     /locus_tag="VYO72_001704"
     CDS             7675..8451
                     /locus_tag="VYO72_001704"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1708033.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8423..8524)
                     /locus_tag="VYO72_001705"
                     /pseudo
     CDS             complement(8423..8524)
                     /locus_tag="VYO72_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            8753..8893
                     /locus_tag="VYO72_001706"
     CDS             8753..8893
                     /locus_tag="VYO72_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708034.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            8930..9484
                     /locus_tag="VYO72_001707"
     CDS             8930..9484
                     /locus_tag="VYO72_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708035.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            9499..10650
                     /locus_tag="VYO72_001708"
     CDS             9499..10650
                     /locus_tag="VYO72_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1708036.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(10702..11361)
                     /locus_tag="VYO72_001709"
     CDS             complement(10702..11361)
                     /locus_tag="VYO72_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1708037.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            11431..>11832
                     /locus_tag="VYO72_001710"
     CDS             11431..>11832
                     /locus_tag="VYO72_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1708038.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQM"
BASE COUNT         3737 a         2080 c         2721 g         3294 t
ORIGIN      
        1 gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg cacgtttatc
       61 aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg ttaaagaaga
      121 aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa atgcgtatgc
      181 aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa aaatcgactc
      241 ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt gtaaagaatt
      301 tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta attcaattat
      361 atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg tagatgatat
      421 cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg aatctcaaac
      481 gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata tgatgaaagc
      541 tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat cccatgttaa
      601 taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact ttatggattt
      661 aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa tgcagcactt
      721 gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg ttcagggctt
      781 gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta tcattggatt
      841 tgataatatt cctatttctc agtattatac tccagctttg tctacaattg ctcccaatta
      901 tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag gggaaagtgt
      961 cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt attgtttaat
     1021 tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt tagcctccat
     1081 tcagtttcta ttgagttgga tccaatttct aacaagtggg acatgttcat gttcgatcta
     1141 aggaagatat ggtcacattc gaatgatatc aaaaaaatcg taaaaaagtc ttgacaaaga
     1201 aaaaacaaag tattaaaata agttcaacaa atcagaaaag taactatttt tgatcttcag
     1261 ggagcctgtg gtgattgtga ataggtggtt ggaagtagtg aaagtgggct gattttgaaa
     1321 atgaatttga aacaatgaaa attcggtgcg cacaccttac agtgcagctt gttgttaaac
     1381 aaggcagaga tgtaaaggga tagtcccttt ataattgagg tggcaccgcg ttaccaacgc
     1441 cctcacacgg aagtatattc tgtgtgtggg cttttttcta tccgtcgttt ggtttatctt
     1501 ttattagggc cttaagtcgc tttgatgaac ttgagttcta tctacagctc cttgcctcct
     1561 actaaaagta aacaaaaagg ctggactaat acgaaaaaag ctagtaatac tcaatgaaaa
     1621 tcaaagagca aactaggaaa ctagccgcag gttgctcaaa acactgtttt gaggttgtgg
     1681 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag
     1741 tcagtaacca tacctacggc aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt
     1801 ataaaggtgt accgagatga acatctcttc atcaatgtct ctggtcgtgg aggcaaggac
     1861 ctagctgcga ttgcagatta ctagaagcta aaaaataata gatggaaaaa ttacagtctt
     1921 ttctctcaca gagagcttgt ggttgctgaa aacaagcaga gaaagctgta aagttgggtt
     1981 catctgaaac gagagaagaa aacatcattc tcaagggagt gccctttatc gcacagcctg
     2041 ttacaggaga tatctgagac aggaatgaga gataggagaa atcctataat tgaggtggca
     2101 ccgcgaattt cgtcctcacg caagttattt tgcgtgggga tttttcatac agtcgccacg
     2161 aactagaatt agaactgaaa gggaaatgac aatggaacga atcattcatg gagatgtctt
     2221 atcaccaatc ttggcttata tgcgcttaaa ggggcaacat aaggttattt tagagagtat
     2281 tccgagagac aaggaaacag ctcgtttttc tatcctagcc tataatccag tttttgagat
     2341 taagtttgaa aatggagttc tctatcaaaa tggtcaagcg attgatcggg atcccttgga
     2401 tttcctttat gaagtgactc ataagagcca gcaccattca gacctccctt ttggtggggg
     2461 agccattggt tttgttggtt acgatatgat ttcgctttat gaagaaattg gtcaaatccc
     2521 tgaggataca attgggacgc cagacatgca tttctttgtc tatgagagct atatggtctt
     2581 tgaccacaag aaggagaaga tacatgtcat agaggatgca ctttatagtg agcgcagtca
     2641 agaggccttg gaaaaatcct tgaaccaagt gcttgaggaa ttacgcattc ctgctccaaa
     2701 tgaatttgaa gacttggatt tatcaccact tgacttcaaa ccgcatatcg ctccacataa
     2761 gtttgaggga atggtagaaa cagctcgtga cttgattcgt aacggagata tgttccaatg
     2821 tgtactcagc cagcgtttct cagcagaagt tactggaaat ccatttgact tctacagaaa
     2881 tctccgcgtg actaatccat ctaattacct ttatttctat gattttgggg attatcaaat
     2941 catcggagct agtccagaaa gtttggtttc tgtcaaaaat ggcatcgtga caaccaatcc
     3001 gattgcaggg acgcgaccaa gaggggctac ggatgaagaa gacaaggcct tggcgactga
     3061 cctcctctct gatgagaagg aaacagcaga acatcgaatg ttggtagact tggggcgtaa
     3121 cgatattggc cgcatctctg aaacggccag tgtccaagtt actaagtata tggaggtgga
     3181 gctcttccgc tacgtcatgc atttgaccag tgtggtcaag ggacgtttgc ttgcagaact
     3241 cactgccatg gatgccttga aagcaacgct tcctgctgga accgtttctg gagcaccaaa
     3301 aattcgagct atgagacgca tctatgaact ggaaacggaa aaacggagcg tatatgcagg
     3361 agcaatcggc tacttgtctg cgacgggtga tatggatttg gccattgcca tccgaaccat
     3421 gattctcaaa aatcaaagag cctatgtgca ggctggggca gggattgtct acgactctat
     3481 cgcccaaaac gaataccaag aaaccattaa caaagcaaaa tctatgacta gaattggaga
     3541 actaagacca tgattttatt gattgacaac tatgattctt ttacctataa cttggcccaa
     3601 tacattggga attttgcaga agttcaggtt ttgagaaatg atgattccaa gctgtatgaa
     3661 gaagctgaaa aagcagatgg tctggtcttt tctcctggtc ctggttggcc agttgatgct
     3721 ggaaagatgg aagacatgat ttgtgatttt gcaggcaaga agccgattct agggatttgt
     3781 ttgggtcacc aagccattgc agaagtcttt ggtggtaagc taggtttggc tccaaaagtc
     3841 atgcatggga aacagagcaa tatcaacttt gaagcgccat ctgttttgta tcaaggtatt
     3901 gaggatggac gtgcggtcat gcgttatcac agtattttga ttgaggaaat gccagaagac
     3961 tttgaagtga cagctcgttc gactgatgac caagccatca tggggattca acataaaaac
     4021 ctaccgattt atggcttcca gtaccatcca gagagcattg gaacgccaga cggcttgtct
     4081 tctattcgga attttatcga gaaggttgta aagtgaggaa actaggatga aagagattat
     4141 tgaaaaacta gcaaaatttg aaaatttatc aggtgtggaa atgacggatg tcattgagcg
     4201 tatcgtaact gggcgtgtaa ctgaagcgca gattgcttct ctcctcttag ctcttaagat
     4261 gaagggggaa acacctgaag aacgtacagc cattgcccaa gtcatgagag gacatgccca
     4321 gcatattcca actgagattc atgatgctat ggacaactgt ggtacaggtg gggacaagtc
     4381 tttcagtttt aatatttcca caactgcagc ctttgtcttg gctggtggcg gtattcacat
     4441 ggccaagcat ggtaaccgct cgatttcttc taaatctggt tccgcagatg tcctcgaagc
     4501 cttgggaatc aatcttgacc tcaaaccagc tgaactaggt aaggtctttg ataaaactgg
     4561 aatcgtcttt ctcttcgcta aaaatatgca cccagctatg aaatacatca tgccagctcg
     4621 tttggaattg ggaattccaa cgattatgaa cttgactggt ccactgattc atccaatggc
     4681 tttagaaaca cagcttcttg gaattagtcg tccagaactc ctagaaagta cagctcaggt
     4741 tttgaaaaat atgggtcgca aacgtgccat cgtggttgct ggaccagaag ggttggatga
     4801 agctggcttg aacggaacaa ccaagattgc acttcttgaa aatggcgaaa tcagcttgtc
     4861 aagctttact ccagaggatt tgggaatgga agactatgct atggaagata ttcgtggtgg
     4921 gaatgctcag gaaaatgcag aaattttgct tagcgttctg aaaaacgaag caagtccatt
     4981 cttggaaacg acagtcttga atgctggtct tggtttctat gctaatggta agattgatag
     5041 catcaaggaa ggagttgcct tggcccgtca agtgattgct agaggcaagg cccttgaaaa
     5101 actcagactg ttacaggagt accaaaaatg agtcaggaat ttttagcacg aatcttagag
     5161 cagaaggcgc gtgaggtgga gcagatgaag ctggagcaaa tccagcctct gcgccagacc
     5221 tatcgcttgg cagaattttt gaagaatcat caggactgct tgcaggtaat cgctgaggtc
     5281 aagaaagcta gccctagttt gggagatatc aatctcgatg tggatattgt gcaacaggcc
     5341 cagacttatg aagaaaacgg agcagtgatg atttcggtgt tgacagatga ggttttcttt
     5401 aaagggcatt tggattatct acgggaaatt tccagtcagg tagagattcc gacgctcaac
     5461 aaagacttta tcatagatga aaagcaaatc atccgcgctc gcaatacagg tgcgacagtt
     5521 atcttgctta ttgtggcagc cttgtccgaa gaacgcctca aggaactgta tgactacgcg
     5581 acagagcttg gtctggaagt cttagtggag actcacaatc tagctgaact agaggtagcc
     5641 cacagacttg gtgctgagat tatcggggtc aacaaccgca acttgactac ctttgaggtc
     5701 gacttgcaga ccagtgtaga tttagcccct tactttgagg aaggtcgcta ttacatttct
     5761 gaatctgcca ttttcacagg gcaggatgcg gaacgactag ccccatactt taacggaatt
     5821 ttggtaggga cagctcttat gcaggcagaa aatgtggccc agagaatcaa ggagttgcag
     5881 attgacaaag gttaaaattt gtggactatc gaccaaagaa gcggtggaaa cagccgtttc
     5941 agcaggagcc gactatatcg gttttgtctt tgcacctagt aaaagacagg tgactttaga
     6001 agaggcagct gagttggcaa agcttattcc tgcagatgtg aaaaaggttg gagtatttgt
     6061 ttcaccaagt cgggtagaac tgctggaagc gattgacaaa gttggcttgg acttggttca
     6121 agttcacggt caggtggcag ctgatttatt tgagaatttg ccttgtgcca gtattcaggc
     6181 tgtgcaggta gatggaaatg ggcatgtccc caattctcag gcagattatc tactctttga
     6241 tgcccctgtg gcaggaagtg gtcagtcctt tgattggggt caactggata cgactggact
     6301 agcacagccc ttctttatcg caggtggcct taatgaagat aatgtagtaa aagcaattca
     6361 acattttact ccctatgcag tagatgtatc gagcggagtg gagacagatg gacaaaaaga
     6421 tcatgaaaag attagaagat ttatagagag ggtaaagcat ggcatatcag gaaccaaata
     6481 aagatggatt ttacggaaaa ttcggcggac gttttgtccc agaaacattg atgacagcag
     6541 ttttggagtt ggagaaggcc taccgtgaaa gtcaggcaga cccaagtttc caagaggaat
     6601 taaaccagct tttgcgccag tacgtaggac gtgaaactcc tctttattac gcaaaaaact
     6661 tgacccagca tatcggcgga gccaagattt atctcaaacg ggaagacctt aaccatacag
     6721 gagcccacaa gattaacaat gccttgggac aagtttggct tgccaaacgc atgggtaaaa
     6781 agaaaattat cgcagaaact ggtgctggtc agcacggtgt ggcaactgca actgctgcgg
     6841 ccctctttaa catggaatgt accatctaca tgggtgagga agatgtcaaa cgccaagccc
     6901 tcaatgtctt ccgtatggag cttttgggag ctaaggtcga ggccgtgaca gatggttcgc
     6961 gcgtgctcaa ggatgcggtc aatgcagctc ttcgttcatg ggtggctaat atagatgata
     7021 cccactatat ccttggttct gccttggggc ctcatccatt tccagaaatt gttcgtgact
     7081 tccaaagtgt cattggtcga gaggctaaac aacagtaccg tgacttgaca ggacaaaatc
     7141 tgccagatgc cctagtagcc tgtgttggtg gtgggtcgaa tgccattggt ctcttccatc
     7201 cctttgtaga agatgagtca gtagccatgt atggagctga agcggctgga cttggtgtgg
     7261 atacggagca ccacgcagct accttgacca agggtcgtcc aggtgtcctt cacggttccc
     7321 tcatggatgt gctccaagat gcccatggtc aaattcttga agccttctct atctcagcag
     7381 gtttggacta tcctggtatc ggtccagagc attctcacta ccacgatatt aaacgtgcca
     7441 gctatgtccc tgtgacagac gaagaagcct tggaaggatt ccaactcttg tctcgtgtgg
     7501 aagggattat cccagccttg gaatctagcc atgctatcgc ctttgcggtg aaattggcca
     7561 aagaacttgg accagaaaag tctatgattg tctgcctatc aggtcgtggg gacaaggatg
     7621 tggttcaagt caaagaccgc ttggaagcag atgcagcaaa gaagggagaa gctcatgcct
     7681 aagacactaa caaaaaaatt aaatgctatt aaagcagctg gaaaaggaat ttttgttccc
     7741 tatatcatgg ctggtgacca cgaaaaaggt ttggatggtc ttgctgaaac aattcacttt
     7801 ttagaagatt tgggtgtctc tgcaattgaa gtgggtattc ccttttcaga ccctgttgca
     7861 gatggacctg ttatcgaaga agctggcttg cgcagtttag cccacgggac ctctacccag
     7921 gctttagttg aaaccttgaa aaccattgaa acagagattc cactggtcat catgacctac
     7981 ttcaaccccc tctttcagta cggtgtggag aactttgtca aagatctggc tgatacagct
     8041 gtgaagggct tgattatccc agacctgcct catgaacatg ccaactttgt agaaccattt
     8101 ttggcagata cagatatcgc cttgattcct ttagtaagct tgaccacagg aattgagcgc
     8161 cagaaagagt tgattgaagg ggcggaggga ttcgtctatg ccgttgccat caatggggta
     8221 acagggaaat caggcaatta ccgtgcagat ttggacaagc acttggcgca acttcatcaa
     8281 gtggccgaca tcccagtctt gacaggtttt ggtgtatcta gtcaagccga tctggaacgc
     8341 ttcaatgcgg tgtcagatgg tgttatcgtc ggttcgaaaa tagtaaaagc tctccaccaa
     8401 ggagagccga ttcaggactt tatcaaacaa gcagtagctt accaaaaata attaaacaag
     8461 tagcaagtaa gaggaaaggc acgaaaggaa gtctttcctt tttcttttgc aggcgaaagg
     8521 ctagttttat agtgaattga atctggaata ttacactacg gttcctaaaa tattttaaga
     8581 aagtgatttg aatttcccaa taaatttgtt cagtttttaa ttgattttac tatagaagat
     8641 ataattttct aaattactct gacacagaac tttaagaaaa agctaattat tgtagtaatt
     8701 tctttaagaa aatgatataa ttcattaaaa agtatttgga ggaggaagaa ttatgttgaa
     8761 tcaggatctc tttgattcgc ttgaggcaca aaaaattgta gatactttga tgaaagggca
     8821 aaaagattat gtagatgaac gtctagaaaa aagagagaca atgatagtgt cgaatggtta
     8881 tgcatggacg tgacctaatc atattgatac tgcatttgca tcagcagatt tgtttgagta
     8941 taaattacaa ttagcaggac agacttgggg atatttagaa tttgaaacaa atacagaaaa
     9001 atatgggaaa gtattgttaa ttataaaggg taagaagcga cttacgaacc aatttccttt
     9061 ggtacaaaaa aataagagtg gctacttatt tgaatatgct cagatgaata cactttatct
     9121 taatcaacat tcttcctaca aaaatgatga agatagtcat tcctttccaa ttcagatgga
     9181 gttagtttct gatgaaatga ttcaagaaat tgaacaagct actaaaaatt cgaatatcga
     9241 aaaatttatg attttaactt atgaggcgga ctcagaaaac aatattatat ctgtagatgt
     9301 tgttatgcct gatgcacgaa ctggtcagtt acacttgatt caagatttgt ctgagtatat
     9361 tcaatcaagt tcgtaccatt tcgaagaagc taaatatcaa gatattccta atttttcaga
     9421 attatcggaa acagaagatt ttgaaattat tccaagaata gaaaaacaag aaggtcaaaa
     9481 gtagtaagga atatgtaaat gtttaatggt cgggtattga aagaattacg gctgttaaat
     9541 ggtttaagta gagcagaatt agctcagaga attaatttaa cggaacaagc catttggcag
     9601 tttgagtcca acgaaacgaa acctaaatta tcaaccaaaa tgcatttggc caaccaattt
     9661 catgttgatt taacttattt tgaacaggaa gaagagagca ttcgatttga ttcttctgta
     9721 attgccttta gaaatgcaga cctagcaaca cggaaaacaa tagatattca aactatgtat
     9781 ttacataagg tagatagttt gattgattat tttgaaagtt ttgtaattat acctaatatt
     9841 acaattcatg acctaagtaa tgtagtgagt gaatcttatc ataagggaga atccattgag
     9901 gaattggctc tttatgccag ggaaaaatta ggtatttcaa aagataatca tgatttgctt
     9961 tataaattag aacgttcagg catctatatc gtggaacgat taattaatgg ccaagctgat
    10021 gcttatagcg catggtcaaa attgggaaga ccttatattg tgttgggaac gaataaatca
    10081 tctgtacgtc gaaattttga cttagctcat gagctaggac atattctttt acacaaatat
    10141 aaagatatga atgaagatgg caatcgtttg gagcaagaag caaattattt tgcatcatgt
    10201 tttttattgc caaaagaaga gtttttagtc aaatttgaag agagggttgg caagcgtgtc
    10261 agcaatcctg atagttatat tttattgaag tcggatttga atgtttcgat acaggcttta
    10321 gagtatcgag cttttaagtt aggattattg actccaaagc aacattctta cttttatcgt
    10381 caaattgcgc aaaaaggtta caaaatgatt gaacctttgg atgatcaaat ttttgttaaa
    10441 aaaccaagca aagtaaagag tattctggac gtcgttttga gtaatcatct agtcagtcta
    10501 gcgactataa tgtctaaaca aagtattcgt ttacagttta taagcgaaat attttcagtc
    10561 gaaatgaaat tttttgatca gtatcaagaa gatagaagaa cagatcgatt tgataacatc
    10621 atccctttgt acaaaagaaa taatttataa tttaactgtg aaataatttc atgaaggaca
    10681 tatggcagaa attggatttt atcagacaag cagtagctta ccaaaaataa tcacacaagc
    10741 agcaagtaag aggaaaggca cgaaaggaag tctttccttt ttcttttgca ggagaaaggc
    10801 cagaataccc gtcgcagaag cgaactgaat caagatcagt aactccgtta cgctaaagac
    10861 gagagcacaa gaagctaaaa agaggaaatc tcctgcgccc atgcggatat cgataaaatg
    10921 agccaaaatt ccaagagcaa ggaaggagac catgaccaga ttccagccag aggaagctat
    10981 taggattagg tggaaagtca tccagaccag taagggatat tcctgatggc gaaagtcgta
    11041 gatgcctaag gtcaaaccag cggtgattag gacgacttgc cccaaggaaa gcaattccca
    11101 agagtaaagc agaaagagga gtcctaagac taattcaaag agggcatacc agacaggata
    11161 gcgaactttg cagtagcgac agcgaaagcg attgaagacc tgtgagagaa tcggaatcaa
    11221 atctaaggga cgcaagcgag tctgacagga atcgcagtga ctggctgaac tgataatgga
    11281 ttgctctgga aaacggtcaa tgaccaaacc aagaaaggaa gcgagaatgc tcccgacgag
    11341 aaaaaaataa aaatcaatca tacttatcta ttcgtaaaaa atgggagaaa tagtataatg
    11401 gagaaacata gataagatgg tgaggaaaag atgacaattc gttttgaaga aaaggtgagt
    11461 atagaaaacg ctcagctcgt atgccaatgg tccaactcct taggcaaagt ctttcaagaa
    11521 caatggatgg gaccaaggat tccttttcta ctgacccttc aagccttgga aggagtcttt
    11581 tcaatctttg atgaacaaga gtttgtggga cttatccaga aaatcaggct agaagacagc
    11641 aatcttcata tcgggagatt ttttatcaac ccccagaaac aggagcaagg cttaggtagc
    11701 caggctttaa ggaaatttgt tagtttggcc tttgaaaatg aagatataga tagtatttct
    11761 ctaaatgtct tcgaggcaaa tcaaagagct cagaatcttt accaaaaaga aggatttgaa
    11821 atcgttcaaa tg
//
LOCUS       DAVLZG010000059        11474 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLZG010000059 DAVLZG010000000
VERSION     DAVLZG010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.059"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            34..6108
                     /locus_tag="VYO72_001711"
     CDS             34..6108
                     /locus_tag="VYO72_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1708039.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVSDKG
                     VPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSNKPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSN
                     QETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSG
                     NTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLEL
                     RNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKND
                     KILYKITAKVEKLQQEIESRYKDNFPFYLAKKGTEETTNFTSFSNLVKAINQNLSGTY
                     HLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEI
                     NLITPPIVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVK
                     ENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANL
                     AEYSIGDSGLLYTPNQFLYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELY
                     LEEQFTKTKEHLAENLKKLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERW
                     YNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLAS
                     HHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLN
                     SFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVA
                     DFDSPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVL
                     DPTTRFKDATDLQKYVHNMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDP
                     ADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTK
                     TINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFR
                     RSIFENKK"
     gene            6152..>11474
                     /locus_tag="VYO72_001712"
     CDS             6152..>11474
                     /locus_tag="VYO72_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1708040.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPV
                     GTTGVDENGNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEE
                     SDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTK
                     ERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDL
                     SKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTN
                     LVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLY
                     KITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLG
                     ADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNV
                     NINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIG
                     NVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGV
                     EGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDD
                     PYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAIN
                     EPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSN
                     LAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIA
                     GQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYI
                     KDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTY
                     LNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMI
                     GGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFD
                     GLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVA
                     HAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIA
                     PIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHV
                     NDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYN
                     YDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMRRNLG
                     DGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPN
                     SAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADK
                     QNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNEL
                     KDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
BASE COUNT         4166 a         1865 c         2358 g         3085 t
ORIGIN      
        1 taacatatat aaattttatt tcaaggagga ataatggaaa agtattttgg tgaaaaacaa
       61 gagcgttttt catttagaaa attatcagta ggacttgtat ctgcaacgat ttcaagttta
      121 ttttttatgt ctgtattagc tagttcatct gtggatgctc aagaaactgc gggagttcac
      181 tataaatatg tggcagattc agagctatca tcagaagaaa agaagcagct tgtctatgat
      241 attccgacat acgtggagaa tgatgatgaa acttattatc ttgtttataa gttaaattct
      301 caaaatcaac tggcggaatt accaaatact ggaagcaaga atgagaggca agccctagtt
      361 gctggtgcta gcttagctgc tctgggaatt ttaatttttg ctgtttccaa gaaaaaggtt
      421 aagaataaaa cggtattaca tttagtattg gttgcgggaa taggaaatgg tgtcttagtt
      481 tcagtccatg ctttagaaaa tcatcttttg ctaaattaca atacggacta tgaattgacc
      541 tctggagaaa aattacctct tcctaaagag atttcaggtt acacttatat tggatatatc
      601 aaagagggaa aaacgacttc tgattttgaa gtaagtaatc aagaaaaatc agcagccact
      661 cctacaaaac aacaaaaggt ggattataat gttacaccaa attttgtaga ccatccatca
      721 acagtacaag ctattcagga acaaacacct gtttcttcaa ctaagccgac agaagttcaa
      781 gtagttgaaa aacctttctc tactgaatta atcaatccaa gaaaagaaga gaaacaatct
      841 tcagattctc aagaacaatt agccgaacat aagaatctag aaacgaagaa agaggagaag
      901 atttctccaa aagaaaagac tggggtaaat acattaaatc cacaggatga agttttatca
      961 ggtcaattga acaaacctga actcttatat cgtgaggaaa ctatagagac aaaaatagat
     1021 tttcaagaag aaattcaaga aaatcctgat ttagctgaag gaactgtaag agtaaaacaa
     1081 gaaggtaaat taggtaagaa agttgaaatc gtcagaatat tctctgtaaa caaggaagaa
     1141 gtttcgcgag aaattgtttc aacttcaacg actgcgccta gtccaagaat agtcgaaaaa
     1201 ggtactaaaa aaactcaagt tataaaggaa caacctgaga ctggtgtaga acataaggac
     1261 gtacagtctg gagctattgt tgaacccgca attcagcctg agttgcccga agctgtagta
     1321 agtgacaaag gcgaaccaga agttcaacct acattacccg aagcagttgt aagcgataaa
     1381 ggcgtaccag aagttcaacc tgaattaccc gaagcagttg taagcgataa aggcgtacca
     1441 gaagttcagc ctgaattacc cgaagcagtt gtaagtgata aaggtgaacc agagcaggta
     1501 gcaccattgc cagaatataa ggggaatatt gagcaagtaa aacctgaaac tccggttgag
     1561 aagaccaaag aacagggtcc agaaaaaacg gaagaagttc cagtaaaacc aacagaagaa
     1621 acaccagtaa atccaaatga aggtactaca gaaggaacct caattcaagg agcagaaaat
     1681 ccagttcaac ctgcagaaga atcaacaacg aattcagaga aagtatcacc agatacatct
     1741 agcgaaaata ctggggaagt atccaataaa cctagtgatt cgacaacctc agttggagaa
     1801 tcaaataaac cagaacataa tgactctaaa aatgaaaatt cagaaaaaac tgtagaagaa
     1861 gttccggtaa atccaaatga aggcacagta gaagggacct caaatcaaga aacagaaaaa
     1921 ccagttcaac ctgcagaaga aacacaaaca aactctggga aaatagctaa cgaaaatact
     1981 ggagaagtat ccaataaacc tagtgattca aaaccaccag ttgaagaatc aaatcaacca
     2041 gaaaaaaacg gaactgcaac aaaaccagaa aattcaggta atacaacatc agagaatgga
     2101 caaacagaac cagaaccatc aaacggaaat tcaactgagg atgtttcaac caaatcaaac
     2161 acatccaatt caaatggaaa cgaagaaatt aaacaagaaa atgaactaga ccccgataaa
     2221 aaggtagaag atccagagaa aacacttgaa ttaagaaatg tttccgacct agagttatac
     2281 agtttgtcaa atggtactta taaacaacac atttcgttag agcaagttcc aagcaatcca
     2341 aatagctact ttgttaaagt gaaatcttct tcattcaaag atgtatacct accagtagca
     2401 tcaatatcag aggaaagaaa aaatgataaa atcctttata aaatcacagc aaaagtagag
     2461 aagcttcagc aggagataga aagcagatat aaagataatt ttcccttcta tctagctaag
     2521 aagggaacag aagaaacaac aaactttact tcctttagta atctggtcaa agctataaac
     2581 caaaatctct ctggaaccta tcatttagga gctagcctga atgctaacga agtggagctt
     2641 agtactgatg ataaatccta tatcaaggga acctttactg gtcagttgat tggtgaaaaa
     2701 gatggtaagc attatgctat ttacaacttg aaaaagcctc tttttgaaaa cttgagtggt
     2761 gctacagtag aaaaactgag tctaaaaaat gttgctattt cagggaaaaa tgatattggt
     2821 tcactggcaa atgaagctac gaatggcaca aagattaaac aagttcatgt tgatggtgtt
     2881 ctggctggag aacgtggtgt cggtggtttg ttggctaagg cagaccaatc aagcatcgca
     2941 gagagcagtt tcaagggaag aattgtcaat acctatgaaa cgactgattc ctacaatatt
     3001 ggcggtctgg tcggtcattt aacaggaaaa aatgcgtcta ttgctaaatc caaagcgaca
     3061 gtaaccattt cgtcaaacac caataggtca gatcagactg tcggtggtct tgcaggtcta
     3121 gtagaccgag atgcacagat ccaagatagc tatgctgaag gtgatatcaa caatgtcaag
     3181 cactttggta gagtcgctgg agtggcaggc aatttgtggg atcgaacttc tggtgatgtt
     3241 aggcatgctg gaagtttgac caatgttctc agcgatgtta atgtaacaaa cggaaatgcc
     3301 atcactggat accactatac aggaatgaag gtagctaata catttagtag taaggctaat
     3361 agagttttca atgtcacttt agagaagaat gaggtcgtca gcaaagaatc cttcgaggaa
     3421 agaggaacaa tgctagatgc ttctcaaatt gcaagcaaaa aagcagaaat caatcttatc
     3481 actccaccaa tagtggaacc cctctcaaca agcggtaaga aagacagtga tttttctaag
     3541 atagcccatt atcaagccaa ccgtgctttg gtttataaga acattgaaaa attgttacct
     3601 ttctataaca aggcgaccat cgtgaaatac ggaaacctgg ttaaggagaa cagtatctta
     3661 tatcaaaaag aactcttgtc tgcagttatg atgaaggatg accaagtaat cacagatatt
     3721 atttccaaca aacagactgc aaacaaactc ttgcttcact acaaggacca ttcatctgaa
     3781 aagtttgatc tcaggtacca ggctgatttt gccaatttgg cagaatatag cattggagat
     3841 agtgggcttc tctatacgcc aaatcaattc ttgtatcatc aagattctat tattaaccaa
     3901 gtgctgcctg aattgaatcg agtaaattat caatcagatg ctgttagaaa tacacttgga
     3961 atttcaccag aagtgaagct aacggagtta tatcttgaag aacaatttac caaaacgaaa
     4021 gagcatctag cagagaactt gaaaaaactt ttatcatctg atgcaggttt agtaacagac
     4081 aatgaagtta tgacaggata tataatagat aaaattaaac ggaataagga agccttactt
     4141 cttggaatga gttatttaga acgttggtat aactttagct atggtcaagt gaatgtcaaa
     4201 gacctagtta tgtatcatcc ggacttcttt ggtaaaggaa atacttcacc attagatact
     4261 ctgattgagt taggtaaatc tggctttaac aatcttcttg ctaaaaacaa tgtcgatact
     4321 tatgctatca gccttgccag ccatcatgga acgacagatt tgtttagcac gttggaaaat
     4381 taccgaaaag tctttctacc agataaaacc aataatgact ggtttaaatc acagactaag
     4441 gcttacattg tcgaagaaaa atccaatatc gaagaggtga aaacgaagca aggactagtt
     4501 ggcactaagt attctattgg tgtctatgac cgtatcacta gtgccacatg gaaataccgt
     4561 aatatggtac tacctctact taccttgcca gaaagatccg tatttgtcat ttcaaccata
     4621 tctagtctag gttttggtgc ttatgatcgc tatcgtaata aagaacatca agcaaatggt
     4681 gatcttaata gctttgttga aaagagtgct cacgaaacag cagagcgtca acgagatcac
     4741 tatgattatt ggtatcgtat tctagatgaa aaagggcgtg aaaagcttta tcgaaatatc
     4801 ttgctttatg atgcctataa atttggaact aatcatactg aaggaaaggc tacagaagta
     4861 gcagattttg atagtccaaa tcctgcaatg aaacatttct ttggacctgt tggaaataag
     4921 gttggacata atggacatgg tgcttatgct acaggggatg cagtatatta tatggggtat
     4981 cgcatgctag ataaggatgg agctattacg tatactcatg agatgacgca taattcagat
     5041 caagatattt atcttggtgg ttatggaaga agaagtggac ttggacctga gttctttgct
     5101 aaaggcttac tacaagcacc agaccaacca agtgatgcaa cgattactat caattctata
     5161 ttgaaacatt caaaatctga tagtaaagaa ggagaacgat tacaagtact tgatccaact
     5221 acgagattta aagacgcaac agatcttcaa aaatacgtcc acaatatgtt tgatgttgtt
     5281 tatatgttgg aatatctcga aggtaaatct attgttaaga aattaaatgt atatcagaaa
     5341 atagaagctc tcagaaaaat cgagaaccaa tatctaacag atcctgctga tggaaatgat
     5401 gtttatgcta ctaatgttgt gaaaaatttg actgaagatg aagctaaaaa attgacgagc
     5461 tttgatagtt tgattgacaa taacattctt tcggctcgtg agtataaggc tggcacttat
     5521 gagagaaatg gctactttac tataaaactc tttgcaccaa tcttttcagc attgagcggt
     5581 gagaaaggaa ctccaggtga ccttatggga cgaaggatag cttttgaact tctagctgct
     5641 aaaggattta aagatggtat ggtaccatat atttccaacc aatacgaaga agatgctaaa
     5701 caacaagggc aaactatcaa tctttatggt aaagaacggg gcttggtgac cgatgagctt
     5761 gttttgaaaa aggtatttga tggtaagtat aaaacttggg cagaatttaa gacagctatg
     5821 taccaagaac gggtggatca gtttggaaac ttgaagcagg tgacctttaa agatccgaca
     5881 aaaccatggc caagatatgg cacaaagact atcaataatg tggatgaatt gcagaaacta
     5941 atggatgaag ctgttttgca ggatgcaaaa gaacgtaatt attattattg gaataactat
     6001 aatccagaaa cggacagtgc cgtccataag ttgaagagag caatctttaa agcctatctt
     6061 gaccaaacaa atgattttag aagatcaatt tttgagaata aaaaatagtg tttactatta
     6121 ggaaataaaa agtgaatgtg gaggattaga attgtcatta ttaaaaaaag ataaattttc
     6181 cattcggaaa ataaagggta ttgttggttc ggtattcttg gggagtcttt tatttgcacc
     6241 gtcagttgtt ggtacatcga cttatcatta cttagattat agtactttga cacaaactga
     6301 acgtgttcaa ctcaaacaag gtagacctga tgaatcaaaa gagtcatatg ctttggttta
     6361 tgaaaaagac gcattaccaa acacaggaag ttctcaatct attatgactg cattgggttt
     6421 gttagctatc gggagtctta ttgtgattat cacaaaagat aaaaagagga aaaaaatcgc
     6481 tacatttttg attgtagggg cgacaggttt agttacacta tcaactgctt cagcacttaa
     6541 tttgaatgct aacatccatg agtctggacg tgatggtgtg ttgcaaattt ctggttacag
     6601 atatgttgat tacttggagc ttgatgatag aactgtttct ccagttgagc aacccaaagt
     6661 tgtgaccgac aaaggcgaac cagaagttca gccagcgtta ccagaagctg ttgtaactgg
     6721 aaaagggaaa actgaagtac aaccgacatt accagaagct gttgtgactg aaaaagggga
     6781 accggaagta caaccagtgt taccagaagc tgttgtggct gaaaaagggg aaccagaagt
     6841 acaaccagcc ttacccgaag cagttgtaac tgaaaaaggc gaaccagaag ttcatgagaa
     6901 gcctgactat acgcaaccaa taggtgcaaa ccttgttgag cctgaagttc atgagaaact
     6961 agcatacact gaacctgtag gtacaacagg agtagatgaa aatggaaact tgattgagcc
     7021 acctgttaac gatattccag agtatactga accaatatct acagtttcag aagttgcatc
     7081 agaaagagaa gagttgcctt ctttacatac cgatattcgt acagagacta ttcctaaaac
     7141 cactatagaa gaatctgatc ctagcaaatt tataggcgat aattctgtta aacaagttgg
     7201 tgaggatggc gaacgtcaaa ttgttactag ctatgaagag ttacatggca aaaaaatcag
     7261 cgagtcagtt gaaacagtaa caattttgaa agaaatgaag cctgaaatta ttgtaaaagg
     7321 tacaaaagaa agaccaaaag aaaaaacggc tcctgtttta accttgacca aagtaacaga
     7381 agatgctatg aatcgttctg ccaacttaaa ttatgagctt gataataaag ataatgctga
     7441 aatatcaagt attgtagctg aaattaaaga tggtgataca gtagttaaaa gggttgattt
     7501 atctaaagaa aaattaactg acgctgtaca aaatttggat ttgtttaaag attataagat
     7561 tgcaacaaca atgatttatg atcgtggtca aggttctgaa acgtctaaac tggatgaaag
     7621 acctctgcgt ttggagttga aaaaggtcga aattaaaaat atcgcatcta ctaatttagt
     7681 gaaggtaaat gatgatggta ctgaaacacc tagtgatttt atgaatgaaa aaccttcaga
     7741 agaagatgtt aaaaaaatgt acttaaaaat cactagtcgc gataataagg taactcgttt
     7801 aactgtagac tctattgaag aagtgactga agaaggtcaa aaactttaca aaataactgc
     7861 tgaagcacaa gatttgattc aacacacaga cccaacgaag gttcgtaata agtatgttta
     7921 ttatatagaa aaaccccatc ctaaagaaga taatgtctac tataacttta aagatttagt
     7981 agatgctatg aatactgata aaaatggtac atttaaactt ggtgcagatt tgaatgccac
     8041 tggtgttcca acacctaaga aatggtatgt tgacggcgac tttagaggta cattgaagag
     8101 tgtagagggg aaacattata ctatccacaa cacggagcgt ccgttattcc agaatattat
     8161 tggtggtaca gtaaccaaag taaatctggg aaatgtaaat atcaatatgc catgggcaga
     8221 ccgcatcgca ccgattgctg acactattaa aggtggcgct aaaattgaag atgtcaaagt
     8281 gactggtaac gtattaggta gaaactgggt atctggattt attgataaga ttgacaacca
     8341 aggtacactc agaaatgtag cctttatcgg aaatgtgaca tctgtaggtg atggtggtca
     8401 attcttgacc ggtatcgttg gtgagaactg gaaaggacta gtcgaacgtg cgtatgttga
     8461 cgcaaatctt attggcaaga aagccaaggc tgctggtatt gcttattgga cacaaaacag
     8521 tggtgacaat cataaagttg gtgtcgaagg tgcagtcaag aaaggaattg tgaagggtac
     8581 cattcaggta gaaagtcctg ttgaagtcgg cggtgctgtt ggacgtttga gtcatcatgg
     8641 ttatatcggg gaagtcgtat ctatgatgaa agttaagaag ggtgaaattt tttatggttc
     8701 tagtgatatg aatgatgacc catattgggt ggcgaataat gtacgaggaa attatgtagt
     8761 taatggtgtg agtgaaggta cgatatctta tgctcgtgct aaagaacacc atcgtatcaa
     8821 accaatttca cagtcagaag cagatactaa aattatgatg ttaggtatta cagcacaaga
     8881 ttttgctatc aacgaacctg tggtcaatcg cttaaaccgt ttaaccagaa aagaagatga
     8941 atataagtca acccaagact ataaagtaga tcgagatctg gcttatcgta atattgagaa
     9001 acttcaacca ttttataaca aagaatggat tgtcaaccaa ggtaacaaac ttgcagaaga
     9061 ttcaaactta gctaagaaag aagtcctttc tgttacgggt atgaaggatg gacagtttgt
     9121 aactgactta tcagatattg ataagattat ggttcactat gctgatggta ctaaagaaga
     9181 aatggacgtc actaagaatg ctgattctaa agtgaaacaa gttcgtgaat ataccatcgc
     9241 tggacaaaac gttgtttata caccaaatat ggttgagaaa gaccgtaacc aattgattca
     9301 agatatcaaa gataagttgg cgtcagttca attgatttct cctgaagtac gtgctttgat
     9361 ggatgcacgt aagaaaccag aagaaaatac tgatgaacgt aagaatggtt atattaaaga
     9421 cctttactta gaagaaagct ttgctgaaac gaaagctaat cttgataaat tggttaaatc
     9481 cttagttgaa aatgcagatc atcaattaaa tagtgacgaa gcggctatga aagcacttgt
     9541 taagaaggtg gatgaaaata aagctaaaat catgatggct ctgacttatc tcaatcgtta
     9601 ctatgatatc aagtatgggg atatgactat caagaacttg atgatgttta aacctgattt
     9661 ctatggtaaa tcagttgacc ttcttgattt cttgattcga attggatcaa gtgagagaaa
     9721 tatcaaaggt gacagaactt tggatgctta tcgtgatatg attggtggaa ctattggtaa
     9781 gtctgaatta catggattct tagattacaa tatgcgtctc ttcactaacg atactgattt
     9841 aaatgattgg ttcatccatg cagctaagaa tgtatatgta tcagaacctc aaacaacgaa
     9901 cccagatttt gttaataaac gacatcgtgc atttgatggt ttgaacaacg gtgttcataa
     9961 tcgtatgatt ctacctctat taactcttaa gaatgcacat atgttcttga tttcaactta
    10021 caatacaatg gcttatagtt cttttgagaa atatggtaag tatacagaag aagctagaaa
    10081 tgaattcaaa aaagaaattg ataaggttgc acatgctcaa caaacatact tagacttctg
    10141 gtcacgttta gcattgccaa gcgtacgtga ccaattactc aagagtgaga atagggtacc
    10201 aactcctgtg tgggataacc aaaactatag tggtattaaa ggaataaacc gtatgggtta
    10261 tgatgagaag aaagtaccaa ttgcgccaat tcgtgagtta tatggtccaa cttggaaatt
    10321 ccataatacc aactggaata tgggagctat ggcatctatt ttcccaaatc ctaataacaa
    10381 tgaccaagtt tatttcatgg gaacaaatat gattagtccg tttggtattt cagcctttac
    10441 tcatgaaact acacacgtta atgatagaat gctttacttc ggtggtcata gacaccgtca
    10501 aggtacagac gtcgaagcct atgctcaagg tatgctacaa actccgtcaa gtattggtca
    10561 ccaaggtgaa tatggtgctt taggtttgaa catggcttat catcgtgaaa atgatggtga
    10621 ccaatggtat aactatgacc ctgataagct tcaaactcgt gaagatatcg atcgatatat
    10681 gaaaaactat aatgaagcac tgatgatgct agatcatgta gaagcagacg ccgtacttcc
    10741 acaattgaat ggtgataata gcaagtggtt caagaaaatt gatagagaaa tgcgcagaaa
    10801 tcttggggat ggtttgaata acttagtagc accgcaccaa tgggacaacg ttcgtgactt
    10861 aaatcaagaa gagagttcta agaaattatc aagtattaac gatttgattg ataataattt
    10921 catgaccaaa cacggaaatc caggtaacgg acgttataga ccagaggatt ttagaccaaa
    10981 ctcagcttac gtaaatgtca atatgatggc aggaatttac ggtgggaata cgagtcaagg
    11041 tgctcctggt tcattatcgt tcaaacataa tgccttccgt atgtggggtt attatggata
    11101 tgacaaaggt ttcactagtt atgtatctag caaatatcaa ggtgaagctg ataaacaaaa
    11161 ccagggtaga ttaggtgatg atttcattat caaaaaagtt tcaaacaacc aattctcaaa
    11221 tcttgaagat tggaagaaat attggtatca tgatgtgaaa tccagagctg aaaaaggatt
    11281 cacagagatt acaattgatg gacaaaccat tcacaactat aatgaactga aagacttatt
    11341 cgacaaagct gtcacagaag acctcaagaa agctggaaac tactcaaata ctgagaattt
    11401 gaaatccaaa gtcttcaaag ctcttcttaa aaacacagac ggtttcttta atccattgtt
    11461 caaaaaagac attt
//
LOCUS       DAVLZG010000060        11470 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLZG010000060 DAVLZG010000000
VERSION     DAVLZG010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.060"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(56..286)
                     /locus_tag="VYO72_001713"
     CDS             complement(56..286)
                     /locus_tag="VYO72_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1708041.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VYO72_001714"
     CDS             complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VYO72_001714"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1708042.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(1113..2036)
                     /locus_tag="VYO72_001715"
     CDS             complement(1113..2036)
                     /locus_tag="VYO72_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1708043.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(2033..2722)
                     /locus_tag="VYO72_001716"
     CDS             complement(2033..2722)
                     /locus_tag="VYO72_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1708044.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(2791..3465)
                     /locus_tag="VYO72_001717"
     CDS             complement(2791..3465)
                     /locus_tag="VYO72_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1708045.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGFAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQIPK
                     RTRKIH"
     gene            complement(3521..4543)
                     /locus_tag="VYO72_001718"
     CDS             complement(3521..4543)
                     /locus_tag="VYO72_001718"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1708046.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGSVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(4673..7144)
                     /gene="parC"
                     /locus_tag="VYO72_001719"
     CDS             complement(4673..7144)
                     /gene="parC"
                     /locus_tag="VYO72_001719"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1708047.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(7564..9507)
                     /gene="parE"
                     /locus_tag="VYO72_001720"
     CDS             complement(7564..9507)
                     /gene="parE"
                     /locus_tag="VYO72_001720"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1708048.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRSDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            9643..10284
                     /gene="plsY"
                     /locus_tag="VYO72_001721"
     CDS             9643..10284
                     /gene="plsY"
                     /locus_tag="VYO72_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1708049.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(10329..11470)
                     /locus_tag="VYO72_001722"
                     /pseudo
     CDS             complement(10329..11470)
                     /locus_tag="VYO72_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3265 a         2567 c         2029 g         3609 t
ORIGIN      
        1 ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac aagacttatt
       61 ttgctaaatt ataattttca atcaaaattt ccacagcttt ttccaatttt ttataaaaac
      121 tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca atttctccga
      181 taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca acattaactt
      241 tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca tacctctctt
      301 cactttttct attttacaag aaaattctaa aactagcaag aaaaaactct atatcaggct
      361 tctctgatat agagttttat gtaaacaacc tcaattgatt tagcatagtt aatagttagt
      421 aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc ctactaactg
      481 caaatcctta tctttgtagt ctacaatagc ttcaatagct acctctatgc ctcttacaat
      541 atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca tcatatatgg
      601 aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat aaagagcttg
      661 gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg ccggaagtcc
      721 ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat aggccgatgc
      781 tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag gtatgcgagc
      841 atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc ctgcttgtcc
      901 aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa cttctgacga
      961 cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa tctcagatgg
     1021 taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag gattaaaacc
     1081 tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta cattaagaat
     1141 atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac gccattctga
     1201 tctttcatat ccatcaatgc tgctggtaga gcgttaaaat tagcagccat tggggtcaat
     1261 aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg attagctccc
     1321 agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc tgcaaaagca
     1381 tttcccataa tcattgtgaa tagaaccatt ccaagaacat aggccaaaac tcctataaag
     1441 cgactatctg aaggaacaat accgctaatc agatgagaga taacatcacc aacacctgct
     1501 acagtaaaaa tagcccccaa agcccctaat aattgaggaa caataccact tgttgaaact
     1561 tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt ggtaatcaca
     1621 agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct aaattctgga
     1681 atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat aaaaatttta
     1741 tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg caaggttccg
     1801 atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat accaatactc
     1861 atatttggca tataggaacc acctataaac gtaatagaca atagagtcca aaatgcagat
     1921 gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt atggagaaat
     1981 tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc tgtcattttt
     2041 gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa ttgtaaatcc
     2101 ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc cctgcataat
     2161 tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc ccagcaccta
     2221 caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgcagccgca cgcgctttta
     2281 ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca gctgcttctc
     2341 ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga attgaaaaga
     2401 aaccagctaa ctctcgaata aagaaataaa ctgtatagaa gtttccaact gtcagacctt
     2461 taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct gacagcccca
     2521 caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat tcttttccca
     2581 aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc aaaccagcta
     2641 agactactgt tgcaattgta tcaaatttta aaataaaacc cacaacaatg attgctattc
     2701 ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca gtattttaaa
     2761 aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc tttttggtat
     2821 ttgccatttt ttaaaaacct cgttatattc ttttgttgta acaatatctt tttgcaattt
     2881 cattccttta aagatatatg gatccccctt aataccaact tgtgagtatg gttttgagaa
     2941 tggtactacg ttacttacaa ctggagaacc accagatgaa gctgttggca tcaataatga
     3001 actatctgtc gaccaagctt gagctttggc atatttttca tatctcttct ctaggtcagt
     3061 ggtctcagaa acagcatctt ctaacaattt cttatattta tccaaaccag gtttagctac
     3121 aacatcctta tcttttcctt tcgtaatacc aaggtgtttc atggcaaaac cagattttgg
     3181 atccataata ttcaagtaag acgctggatc ttgatagctt ggagcccatc ctgtactatt
     3241 caaatcatag tctttttgag aaggagcaac attgccgtat ttatcatttt ccatcaaacc
     3301 atcaataaca tttccaataa cgtctgtcgt cgatgttcga gtcgctatac tgtagcccaa
     3361 tgatgctgga tctactgcat agacataaga aaatgttgtc ggtgcatcgg cttctttatc
     3421 agtttttcca caagccacta aaatagctga cgtgctcagg accactcctg ctgttaagag
     3481 ccactttttc tatttcataa aaaatctcct tcggtttatt ttaatctact tttacaatcc
     3541 aaccttctgg cgcttcaata tcgccaaact gaatacccgt caattcatta tataatttac
     3601 gcgtcacaga acctacttct gtttcactat agaatacatg gaaatcatca ccatgttgaa
     3661 tacctccaat tggagaaata accgctgctg taccacaggc acctgcctct acaaaacggt
     3721 caagattatc aattggaaca tcaccctcaa taggagttaa tcccaagcgg tgttctgcca
     3781 aataaagcaa ggaatacttg gtaatagatg gcaagataga tggactcaat ggtgttacaa
     3841 attcattatc agctgtaatt ccaaagaaat tagctgatcc gacttcttca atctttgtat
     3901 gagttgatgg gtccagatag ataacatctg agaaatggcg tgacttggcc atttttcctg
     3961 gtaagagact tgcagcatag tttccaccaa ccttagccgc acctgtacca tttggtgctg
     4021 cacggtcgta ctcatcctga atcaagaagt tggttgggac caaaccacct ttaaagtaat
     4081 ttccaactgg catagcaaag atggtgaaaa tgtactcttc tgccggtttt accccgataa
     4141 tatctccgac accaatcaaa agagggcgaa gatataaggt tccacctatt ccgtatggtg
     4201 gtacgtattc ttcattcgca cggacaactg ctttacaagc ttctacaaac atgtctgtcg
     4261 gaacttgtgg catcaagaga cggtcacatg tacgttgcag gcgtttagca ttttcatcag
     4321 gacggaacag ttgaacactg ccatccttag tacgataagc tttcaaacct tcaaatgctt
     4381 gttgtccata gtgaagactt ggagaagact ctgaaatatg caaagttgca tcctctgtaa
     4441 gctctccttg atcccattgt ccatttttga aatgagcaag atagcgataa ggtaatttca
     4501 tataggaaaa accgaggttt tcccaatcaa tcgttactgt catattccac tccttattct
     4561 aaaaacctat ttcttatatt ctacactatt tttctaaaat agcaagtata ttttgtaatt
     4621 ttcagaaaat tcctccaata aaaaccatct tagaactgat tcttcatttc acttatttat
     4681 cttcagtaac tacttcctga agataagcgt caaaaacttc ttcatctgaa atcgtgtcag
     4741 aaatgaagct tccattgcta gtgcgttctg acaagttcaa gtcttgcaat cggctttcat
     4801 agattgttcc tttattggat tggacaagca gagtttggtc gttcacatcc acttccgtac
     4861 tgaagaaatc gccaacaaat ccttgctctg caactgctcc tgccaagaag acacgatgcg
     4921 gtttgttttt caactcacgc aagacttgta atcctcgttt ggcacggctg gttgctagaa
     4981 tttcctcaat ggaaacacgt ttcaagcttc cacgctgggt caagaggtag aaggacgaag
     5041 tattacagat aaagccagat tggaggacat catcttcttt caaattcata gccttgacac
     5101 ctgctgcctt agcaccgaca accggaacct cttcgatatt gaaacgcagg gcataaccat
     5161 tttgactaac caagacaaca tcatctagtt taatcggagc cactgctaca atctgatctg
     5221 tatcgtcttt gagcttagca tacttgacag acttagatct ataggtccgc catggagtga
     5281 attcttttcg ctctacccgt ttgatttgac caaggcgagt cgctgcaaag taggttgtcg
     5341 catcgtcaaa ctgatccagt acttccacat aaaggatttc ttcattcgtt tcaaagtttg
     5401 tgatggtttg gctcagatgc tctccgatgt ccttccaacg aatatctgcc aactcatgga
     5461 ttggtctgta gatgacattt ccaagacttg tgaacatcaa gaggtgctgg gttgtcttgg
     5521 cagattgaac aaaaatcaaa cggtcatcat cacgcttgcc aatttcttcc aaggtggaag
     5581 ccgcaaagga acgtggactg gtacgcttga tgtaacctgc cttggtcacg ctgacgtagg
     5641 tatcttcctc agcgataaga ctagctgtat caatctcaat tgctttcgca gtgtcttcta
     5701 aagaactcaa acgaggagtt gcaaatttct tcttgacctc acgaagttct ttcttcatga
     5761 gattgtacat agtcctttca tcaccaataa tagccgccag catagcaatc ttctcacgaa
     5821 gctctgcttc ttcttcctgc aagacaacca catcggtatt ggtcaaacgg tacagttgca
     5881 aagttacgat agcctcagcc tgttcttccg taaaatcata gctaactttg aggttttcct
     5941 tggcgtccgc cttattctca gaagcacgga taagagcaat gacttcatcc aaaatcgaaa
     6001 tcacacgaat caaaccttcg acgatatgga gacgtttctc agccttttct ttgtcaaagc
     6061 gtgaacgcgc caaaatcact tctcgacggt gagcgatgta gctagacagg attggaacaa
     6121 tcccaacctg acgaggtgtg aaattgtcaa tcgccaccat attaaagttg tagttgattt
     6181 gtaggtcggt gtacttaaat aagtagttga gaacaagctc agtattagcg tctttcttaa
     6241 gttcgatagc gatacgaaga ccatcacggt cagactcatc acgaacctca gcaatcccag
     6301 ctaccttgtt attaacacga acatcatcga ttttcttgac tagattggcc ttattgattt
     6361 cataaggaat ctcagtaata acgatttgtt ccttaccacc ttttagcttt tcaatttcag
     6421 tcttggaacg aacaaccacg cgccctttcc cagtctcata agctttcttg atttcatcac
     6481 gaccctgaat aatagcccct gtagggaagt ctggtccagg caagaattcc atgagtttat
     6541 caatctttgc agttgggtgg tcaatcatgt aaactgcagc atctatgacc tcagctaaat
     6601 tatggggagg aatgtctgtg gcataaccag ccgaaatccc agtcgaacca ttgaccaaga
     6661 ggtttggaaa ggctgctggc aagaccgttg gttctttctc cgtatcgtca aagttccatg
     6721 caaaaggaac tgtctttttc tcgatatcct gaagaaggta gcctgcaatt tcagacaaac
     6781 gtgcctcagt ataacgcata gccgcaggag gatctccgtc catagaaccg ttattaccgt
     6841 gcatttcaac tagaatctca cgatttttcc agttctgtga catacgaacc atggcatcat
     6901 agatagaaga atccccgtgt gggtggaaat tccccatgat gttcccgact gacttggccg
     6961 acttacggta gctcttgtca aaagtattgc tatccttatt catagaataa agaatacggc
     7021 gctgaaccgg cttcaaccca tcacgaatat ctggcaaagc ccggtcttga ataatgtact
     7081 tggagtagcg accaaagcgc tctcccatga tgtcctccag ggacatgttt tgaatgttag
     7141 acataagata caaagcccat aaaataccaa gtgaaaatag aaaattcttg aagtaagcaa
     7201 actcacaaga gaatttatct ttttcacaca atatctaggg cgtgttcaac tcctttcaaa
     7261 gaatgtagag taggttttta tgcagtaaaa gatattttac gggaattcgt cccgtgttca
     7321 gttacgataa gtaaccaaac tatcctgttt gtatttttca atatgaaaat ctggttttcc
     7381 aaaattagtc ttagtttgtg tcttagccgc tcccttaaac gcctctttga gataagcact
     7441 catagaagat tcttcattaa taattctgca attttttcaa accaagattt tcaaactgct
     7501 ttttcacata gtcattcaca tccgactcta atttccagtt tactaacata ttattttctt
     7561 tcattaaaac actgtcgctt cttctagcgt aaacttgaca ttatcttcaa tccatttacg
     7621 gcgtggttct accttatctc ccatgagaac attgacgcga cgttcggcgc gcgctaaatc
     7681 ttcaattgtg acacggatga gggtacgtgt ttctgggttc atggttgttt cccagagctg
     7741 gtccgcattc atctcaccaa gtcctttgta tcgttggagg gtagcgcctt taccgaactg
     7801 tttacgtagt tcttctagtt ctccgtccgt ccaagcgtag gccacttctt ctttcttgcc
     7861 tttacctttg gacatcttgt aaagaggtgg gagggcaata tagacatgac ctgcctcgac
     7921 tagcggacgc atgtaacggt agaaaaatgt caagagcaag gtctggatat gggcaccgtc
     7981 ggtatccgca tcggtcatga taatgatctt atcatagttg gcatcttcaa tagagaagtc
     8041 tgctccaaca cccgcaccaa tggtataaat catggtattg atctcttcat ttttgaggat
     8101 atccgccatc ttggccttgg ctgtattgat aaccttacca cgaagaggta gaatagcctg
     8161 gaacttgcgg tcacgacctt gtttggcaga accaccggca gagtccccct caactagata
     8221 gagttcattc ttagcaggat tcttagattg ggctggggtc aatttcccag acaacaagcc
     8281 cttatctttc ttgtttttct tcccatttcg gctctcatca cgcgccttac gtgctgcttc
     8341 acgagcatca cgggccttga tagccttgcg gatgaggtta gaagctaatt ccccattttc
     8401 cataaggaaa aaggtcaact tatcagccac tattccatcc acaactgggc gagctaaggg
     8461 gcttcctagt ttatccttgg tctgtccttc aaactgcaag tgttcttcag gaactaagat
     8521 agaaagaacg gccgctagtc cctcacgata gtctgaacct tcaaggtttt tatctttttc
     8581 cttgagaaga cctgttttac gtgcatagtc attcatgacc ttggtaatgg cagacttgag
     8641 tcctgtctcg tgcgttccac cgtccttggt gcgaacgtta ttgacaaagg atagaatgtt
     8701 atctgagaat ccgtcattgt actggagggc tacttccact tgaaaaccat tgtcttcccc
     8761 ttcaaagtaa agaactggcg tcaagatttc cttatcttcg ttgagataag aaacaaaatc
     8821 ttgtactcca ttctcatagt ggaactcaat cgcttcatct gatcgcttgt ccgttaaaga
     8881 caaggtcaca tttttcaaga gaaaggctga ttcattaagg cgctctgaaa tggtattgta
     8941 cttgaaatct gtcgtagaaa agatagtcgc gtcaggcata aaagtaactt tggtgcctgt
     9001 tttagacttg ggtgctgtac cgactttctt caaagtcgtg acaggttttc caccattttc
     9061 aaaacgttgc ttgtaaactg cgccatcacg ggtaatttca acttctaacc agctagaaag
     9121 ggcgttaaca acggaagaac ccactccgtg aagtccacct gatgtcttat agccaccttg
     9181 accgaatttc cctccggcat gaagaatggt aaagataacc tcaacagttg gaattcccat
     9241 agcgtgcata cctgtcggca tcccacgtcc atggtcttga accgttagac taccgtcttt
     9301 attgatagtt acatcaatac gatcaccaaa cccagacaag gcttcatcga ctgcattatc
     9361 aacgatttcc caaactaggt gatgaagacc agcgccatcg gtcgatccaa tatacatccc
     9421 tggacgtttt cggaccgcat ccaacccttc tagcacctga atagcatcat cattataatt
     9481 gttaatattg atttcctttt ttgacacaag gaacctccta ttcgttcatc tttactattc
     9541 tacaggtttt ccaaggattt tgcaaaattt ttctttctcc gatgtgacaa tttcagcaga
     9601 gattctctgc ttttctttcc caattcatga tataatagga gtatgattac aataatttta
     9661 ttaatcctag cctatctgct gggttcgatt ccatctggtc tctggattgg acaagtattc
     9721 tttcaaatca atctacgcga gcatggttct ggtaacactg gaacgaccaa taccttccgc
     9781 attttaggta agaaagctgg tatggcaacc tttgtgattg actttttcaa aggaacccta
     9841 gcaacgctgc ttccgattat ttttcatcta caaggcgttt ctcctctcat ctttggactt
     9901 ttggctgtta tcggccatac cttccctatc tttgcaggat ttaaaggtgg taaggctgtc
     9961 gcaaccagtg ctggagtgat tttcggattt gcgcctatct tctgtctcta ccttgcgatt
    10021 atcttctttg gagctctcta tcttggcagt atgatttcac tgtctagtgt cacagcatcg
    10081 atcgcggctg ttatcggggt tctgctcttt ccactttttg gttttatcct gagtaactat
    10141 gactctctct tcatcgctat tatcttagca cttgctagtt tgattatcat tcgtcataag
    10201 gacaatatag ctcgtatcaa aaataaaact gaaaatttgg tcccttgggg attgaaccta
    10261 acccatcaag atcctaaaaa ataaaatgcc agttctgtga actgcccccc aaaagttaga
    10321 caaataattt atccaaagga tttagttctg tactgcacag gactaagtcc ttttagtttt
    10381 accttaattc gtttattgtt gtagtaatca acatagtcta caatagcttg ttccaattgc
    10441 ttaagcgact gaaacgactt ctcataaccg taaaacattt ccgatttcag aatcccaaag
    10501 aaggactcca tcataccatt gtctgggctg ttacccttac gtgacataga tgcttgaatt
    10561 cccttactct ctaggaaccg atgataagaa tcgtgtcggt attgccagcc ttggtcacta
    10621 tggagaatcg tattctcata gtgcttctct gtgaatacct gttccaacat tgtttgtact
    10681 tgttctaagt tgggtgaagt tgaaagatta taggcgataa tttcgctatt aaagccatct
    10741 aaaactggtg ataagtaaag cttttgagta cttgctggaa tggcaaattc tgtcacatct
    10801 gtgtagcact tttccattgt tttagagcct tcaaattggc cttgaatgag attctctgct
    10861 ttcttaccaa cgtctccttt atgagaagaa tattttcgtt tctgtcgcat tttagcttgt
    10921 aaattgagta cttttatcaa gccttgaact cttttatgat ttaccagata agcacgattt
    10981 cttagttcta aatgaacccg gcgataagca taatttcctt tgtgttcgat aaagatggat
    11041 tgaatttcag ctttaagctc ttggtcctta tctgttttgt ctagctgttt caagtgatag
    11101 tagtaggtcc aacgagctag tttaatggat tttagaagaa gaactaacga aaactcagtc
    11161 attaattctt gaacaatttc tgtccttctt ctttctcttt ttcctccttc aatcggagtt
    11221 ctcttaactt ttttaggatg gcattctccg ctctcaggta ctcattttct gcttgaagat
    11281 attctaattc tgtcctctct tcaggtctcg tttttggctt acgtcccatt ttaggtactc
    11341 tccctcttgt tttctcaaca atagtatacc cgtttttcct gtattgtgct agccagttaa
    11401 gaagtatcgt acgacttggg aggccgtatt caagagaaac tctatcttta gtccagcctt
    11461 catgtcagac
//
LOCUS       DAVLZG010000061        11344 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLZG010000061 DAVLZG010000000
VERSION     DAVLZG010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.061"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            643..1635
                     /locus_tag="VYO72_001723"
     CDS             643..1635
                     /locus_tag="VYO72_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1708050.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1637..2455
                     /locus_tag="VYO72_001724"
     CDS             1637..2455
                     /locus_tag="VYO72_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1708051.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2457..3242
                     /locus_tag="VYO72_001725"
     CDS             2457..3242
                     /locus_tag="VYO72_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1708052.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3340..3558
                     /locus_tag="VYO72_001726"
     CDS             3340..3558
                     /locus_tag="VYO72_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1708053.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3543..3740
                     /locus_tag="VYO72_001727"
     CDS             3543..3740
                     /locus_tag="VYO72_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1708054.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(4163..4240)
                     /locus_tag="VYO72_001728"
                     /pseudo
     CDS             complement(4163..4240)
                     /locus_tag="VYO72_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4472..10906
                     /locus_tag="VYO72_001729"
     CDS             4472..10906
                     /locus_tag="VYO72_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1708055.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKGLSNLKNTKVLYT
                     YDRIFNGSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVI
                     SREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADQADEK
                     GMISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEG
                     EASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKRNIIA
                     YDDGSALQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         3961 a         1706 c         2282 g         3395 t
ORIGIN      
        1 aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt aagtgttatt
       61 ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt gaagctgata
      121 aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt tataatgaga
      181 ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt tggtttaggt
      241 agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga atgaggtaaa
      301 agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag agggagtatc
      361 cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg ttggtaattt
      421 aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat cctaatttca
      481 caatccatag gcaaactctt gcatttcgtt ttttattgga ctataatagg ttggtataaa
      541 gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa tatttgtagt
      601 taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat gatagaagtg
      661 gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa gggggctttg
      721 cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt gacctttgag
      781 gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa gtcgacaacc
      841 attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat taacggcaag
      901 attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt tggacaacgc
      961 acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa agagatttat
     1021 gatgtgccaa actcgctctt tcataagcgc atggactttt tgaatgaagt cttggatttg
     1081 aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat gcgggcggat
     1141 attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc gaccattggt
     1201 ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa tcaagaggaa
     1261 gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact ttgtgatcgg
     1321 attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca actcaaggag
     1381 acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag tcatctcgtc
     1441 tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag cctcaacatt
     1501 gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct gtctgatttt
     1561 gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg tcgcttctac
     1621 cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta tcaatgcagg
     1681 ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg gcgatgtcat
     1741 gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc aagagtcttt
     1801 gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt ttgtgaccaa
     1861 tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg atggctccat
     1921 tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca ccgagcttgg
     1981 ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca ttgtcttgat
     2041 gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc tttatctttt
     2101 tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg gattttcagc
     2161 ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag tggcttttat
     2221 gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata ttctttcctt
     2281 tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa aatacgatgc
     2341 cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga tggtgggatt
     2401 gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag gttagtatga
     2461 aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa atcatggaat
     2521 ataaggtgga ttttgtggtt ggtgtcttgg gagtctttct ggctcaaggc ttgaatctct
     2581 tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc tttcaagaga
     2641 tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc ttttttgaca
     2701 atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag tatttgactc
     2761 gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat gccttgggtg
     2821 aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt tggactcttc
     2881 caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat acttctctta
     2941 aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg atttacatct
     3001 tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct cttcttcgtt
     3061 ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct agctatttct
     3121 tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct ctggttttct
     3181 ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt gcgggttcgt
     3241 aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa ttgaagaagt
     3301 caaggatgaa aatcaaaaaa ggcagttgtc gctgaggttt tgaaggattt gccagaatgg
     3361 tttggaatcc cagaaagcac acaagcctat atagaaggaa ccacgacact gcaagtttgg
     3421 accgcctatc aggagagtga tttgactgga tttgtaaggt tatcctattc gagtgaagat
     3481 tgtgcagaga ttgattgtct cggcgtaaaa aagcttatca aggtagaaaa attgggagcc
     3541 aattgcttgc tactttagag agtgaagctc gtaaaaaagt tggttatctg caggtcaaaa
     3601 cagtggcaga agcttctaat aaagattatg atcgaacaaa tgacttttat cgaggtcttg
     3661 gctttaaaaa gttagagatt ttttctcagc tatggaatcc gcaaaatcct tgtcagattt
     3721 tgattaaaaa gcttgaataa tattacttga catctattct cagagtgcca tactgtaagt
     3781 gtaatcgccg atttagctca gttggtagag caaggcactc gtaaagccta ggttataggt
     3841 agataaacga ctgaggagtt gaaaaaatag ataggtagaa gataaccgtt aagccttatt
     3901 cttagcggtt atttatatta tttaatagcg ctgatatttc atcaattatg cctgttttcg
     3961 tgtttctggt agttgttcaa gtttattgct actatttttg atggtatgaa tgtgcttata
     4021 atgtatcccg gttaacgaaa gttttggact tatactcttc gaaaatctct tcaaaccacg
     4081 tcaacgtcgc cttgccgtgc gtatggttac tgactacgtc agttctatcc acaacctcaa
     4141 aacagtgttt tgagctgact acgtcagttc tatccacaac ctcaaaacag tgttttgagc
     4201 aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtactaa tcttattttt
     4261 taacgtgtgc taaaaaataa attaatgcat gttaattttt ttgacttaaa tttttttaaa
     4321 tgatatactg tttttataga gagataacaa ttatatataa atgtactact ctatttccta
     4381 gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt tattatctat
     4441 tggaagttaa ataaatatgt aaggaattaa aatgaaaaaa agcacagtat tgtcattaac
     4501 tacagctgca gttattttag cagcctatgc ccctaatgag gtagtcttag cagacacatc
     4561 tagctctgaa gatgctttaa gcatctctga taaagaaaaa gtagtagtag ataaggaaac
     4621 agaaaataaa gagaaacata aagatattca taatgctata gaaacttcaa aggatactga
     4681 agaaaagaaa acaacaatta ttgaggaaaa agaagttgtt agtaaaaatc ctgtaataga
     4741 cactaaaact agcaatgaag aagcaaaaat caaagaagaa aattccaatc aatcccaagg
     4801 agatcatacg gactcatttg tgaataaaaa cacagaaaat cccaaaaaag aagataaagt
     4861 tgtctatatt gctgaattta aagataaaga atctggagaa aaagcaatca agggactatc
     4921 aaatcttaag aatacaaaag ttttatatac ttatgataga atttttaacg gtagtgccat
     4981 agaaacaact ccagataact tggacaaaat taaacaaata gaaggtattt catcgattga
     5041 aagggcacaa aaagtccaac ccatgatgaa tcatgccaga aaggaaattg gagttgagga
     5101 agctattgat tacctaaagt ctatcaatgc tccgtttggg aaaaattttg atggtagagg
     5161 tatggtcatt tcaaatatcg atactggaac agattataga cataaggcta tgagaatcga
     5221 tgatgatgcc aaagcctcaa tgagatttaa aaaagaagac ttaaaaggaa ctgataaaaa
     5281 ttattggttg agtgataaaa tccctcatgc gttcaattat tataatggtg gcaaaatcac
     5341 tgtagaaaaa tatgatgatg gaagggatta ttttgaccca catgggatgc atattgcagg
     5401 gattcttgct ggaaatgata ctgaacaaga tatcaaaaac tttaacggca tagatggaat
     5461 tgcacctaat gcacaaattt tctcttacaa aatgtattct gacgcaggat ctgggtttgc
     5521 gggtgatgaa acaatgtttc atgctattga agattctatc aaacacaacg ttgatgttgt
     5581 ttcggtatca tctggtttta caggaacagg tcttgtaggt gagaaatatt ggcaagctat
     5641 tcgggcatta agaaaagcag gcattccaat ggttgtcgct acgggtaact atgcgacttc
     5701 tgcttcaagt tcttcatggg atttagtagc aaataatcat ctgaaaatga ccgacactgg
     5761 aaatgtaaca cgaactgcag cacatgagga tgcgatagcg gtcgcttctg ctaaaaatca
     5821 aacagttgag tttgataaag ttaacatagg tggagaaagt tttaaataca gaaatatagg
     5881 ggcctttttc gataagaata aaatcacaac aaatgaagat ggaacaaaag ctcctagtaa
     5941 attaaaattt gtatatatag gcaaggggca agaccaagat ttgataggtt tggatcttag
     6001 gggcaaaatt gcagtaatgg atagaattta tacaaaggat ttaaaaaatg cttttaaaaa
     6061 agctatggat aagggtgcac gcgccattat ggttgtaaat actgtaaatt actacaatag
     6121 agataattgg acagagcttc cagctatggg atatgaagcg gatgaaggta ctaaaagtca
     6181 agtgttttca atttcaggag atgatggtgt aaagctatgg aacatgatta atcctgataa
     6241 aaaaactgaa gtcaaaagaa ataataaaga agattttaaa gataaattgg agcaatacta
     6301 tccaattgat atggaaagtt ttaattccaa caaaccgaat gtaggtgacg aaaaagagat
     6361 tgactttaag tttgcacctg acacagacaa agaactctat aaagaagata tcatcgttcc
     6421 agcaggatcc acatcttggg ggccaagaat agatttactt ttaaaacccg atgtttcagc
     6481 acctggtaaa aatattaaat ctacgcttaa tgttattaat ggcaaatcaa cttatggcta
     6541 tatgtcagga actagtatgg cgactccaat cgtggcagct tctactgttt tgattagacc
     6601 gaaattaaag gaaatgcttg aaagacctgt attgaaaaat cttaagggag atgacaaaat
     6661 agatcttaca agtcttacaa aaattgccct acaaaatact gctcgaccta tgatggatgc
     6721 aacttcttgg aaagaaaaaa gtcaatactt tgcatcacct agacaacagg gagcaggcct
     6781 aattaatgtg gccaatgctt tgagaaatga agttgtagca actttcaaaa acactgattc
     6841 taaaggtttg gtaaactcat atggttccat ttctcttaaa gaaataaaag gtgataaaaa
     6901 atactttaca atcaagcttc acaatacatc aaacagacct ttgactttta aagtttcagc
     6961 atcagcgata actacagatt ctctaactga cagattaaaa cttgatgaaa catataaaga
     7021 tgaaaaatct ccagatggta agcaaattgt tccagaaatt cacccagaaa aagtcaaagg
     7081 agcaaatatc acatttgagc atgatacttt cactataggc gcaaattcta gctttgattt
     7141 gaatgcggtt ataaatgttg gagaggccaa aaacaaaaat aaatttgtag aatcatttat
     7201 tcattttgag tcagtggaag aaatggaagc tctaaactcc aacgggaaga aaataaactt
     7261 ccaaccttct ttgtcgatgc ctctaatggg atttgctggg aattggaacc acgaaccaat
     7321 ccttgataaa tgggcttggg aagaagggtc aagatcaaaa acactgggag gttatgatga
     7381 tgatggtaaa ccgaaaattc caggaacctt aaataaggga attggtggag aacatggtat
     7441 agataaattt aatccagcag gagttataca aaatagaaaa gataaaaata caacatccct
     7501 ggatcaaaat ccagaattat ttgctttcaa taaccaaggg atcaacgctc catcatcaag
     7561 tggttctaag attgctaaca tttatccttt agattcaaat ggaaatcctc aagatgctca
     7621 acttgaaaga ggattaacac cttctccact tgtattaaga agtgcagaag aaggattgat
     7681 ttcaatagta aatacaaata aagagggaga aaatcaaaga gacttaaaag tcatttcgag
     7741 agaacacttt attagaggaa ttttaaattc taaaagcaat gatgcaaagg gaatcaaatc
     7801 atctaaacta aaagtttggg gtgacttgaa gtgggatgga ctcatctata atcctagagg
     7861 tagagaagaa aatgcaccag aaagtaagga taatcaagat cctgctacta agataagagg
     7921 tcaatttgaa ccgattgcgg aaggtcaata tttctataaa tttaaatata gattaactaa
     7981 agattaccca tggcaggttt cctatattcc tgtaaaaatt gataacaccg cccctaagat
     8041 tgtttcggtt gatttttcaa atcctgaaaa aattaagttg attacaaagg atacttatca
     8101 taaggtaaaa gatcagtata agaatgaaac gctatttgcg agagatcaaa aagaacatcc
     8161 tgaaaaattt gacgagattg cgaacgaagt ttggtatgct ggcgccgctc ttgttaatga
     8221 agatggagag gttgaaaaaa atcttgaagt aacttacgca ggtgagggtc aaggaagaaa
     8281 tagaaaactt gacaaagacg gaaataccat ttatgaaatt aaaggtgcag gagatttaag
     8341 aggaaaaatc attgaagtca ttgcattaga tggttctagc aatttcacaa agattcatag
     8401 aattaaattt gctgatcagg ctgatgaaaa ggggatgatt tcttattacc tagtagatcc
     8461 tgacaaagat gcttctaaat atgaaaaact tggtgaaatt tctgaagata aactcaaaaa
     8521 tgcaaagagc ccagaggaaa ataccaataa taatcaagct aaggatgaag attcaaaacc
     8581 agatgaaaaa agttcagttg agggagaagc tagccttgaa ataaataaaa ctatttcaac
     8641 aattagagag tttgaaaata aagacctaaa gaaactcatt aaaaagaaat ttagagaagt
     8701 tgatgatttt acaagtgaaa ctggtaagag aatagaggaa tacgattata aatacgatga
     8761 taagagaaat attattgctt atgacgatgg tagtgcctta caatatgaaa ctgaaaaatt
     8821 tgacgaaata aaatcaaaaa tttatggtgt tctaagccca tctaaagatg gacactttga
     8881 aattcttgga aagataagca atgtttctaa aaatgccaag gtatattatg gaaatagcta
     8941 taaatcgata gaaatcaaag cgactaagta tgattcacat tcaaaaacga tgatatttga
     9001 tttatacgct aatattaatg atattgtaga tggattagct tttgctggag atatgagatt
     9061 atttgttaaa gatgacaatc aaataaaagc tgaaactaag attagaatgc ctgaaaaaaa
     9121 taaggaaact aaagcagaat atccctatgt atcaagttat gggaatgtaa tcgaattagg
     9181 agaaggagat ctttcaaaga acaaaccaga caatttaact aaaatggaat ctggtaaaat
     9241 ctattctgat tcagaaaaac aacaatatct gttaaaggat aacatcattc taagaaaagg
     9301 ctatgcacta aaagtgacta cctataatcc tggaaaaacg gatatgttag aaggaaatgg
     9361 agtctatagc aaggaagata tagcaaaaat acaaaaggcc aatcctaatc taagagtcct
     9421 ttcagaaaca acaatttatg ctgatagtag aaatgttgaa gatggaagaa gtacccaagc
     9481 tgtattaatg tcggctttgg acggctttaa cattataagg tatcaagtgt ttacatttaa
     9541 aatgaacgat aaaggggaag ctatcgataa agacggaaat cttgtgacag attcttctaa
     9601 acttgtatta tttggtaagg atgataaaga atacactgga gaggataagt ccaatgtaga
     9661 agctataaaa gaagatggct ccatgttatt tattgatacc aaaccagtaa acctttcaat
     9721 ggataagaac tactttaatc catctaaatc taataaaatt tatgtacgaa atccagaatt
     9781 ttatttaaga ggtaagattt ctgataaggg tggttttaac tgggaattga gagttaatga
     9841 atcggttgta gataattatt taatctacgg agatttacac attgataaca ctagagattt
     9901 taatattaag ctgaatgtta aagacggtga catcatggac tggggaatga aagactataa
     9961 agcaaacgga tttccagata aggtaacaga tatggatgga aatgtttatc ttcaaactgg
    10021 ctatagcgat ttgaatgcta aagcagttgg agtccactat cagtttttat atgataatgt
    10081 taaacctgaa gtaaacattg atcctaaggg aaatactagt atcgaatatg ctgatggaaa
    10141 atctgtagtc tttaacatca atgataaaag aaataatgga ttcgatggtg agattcaaga
    10201 acaacatatt tatgtaaatg gaaaagaata tacatcattt gatgatatta aacaaataac
    10261 agacaagaca ctaaacatta agattgttgt aaaagatttt gcaagaaata caaccgtaaa
    10321 agaattcatt ttaaataaag atacgggaga ggtaagtgaa ttaaaacctc atagggtaac
    10381 tgtgaccatt caaaatggaa aagaaatgag ttcaacgata gtgtcggaag aagattttat
    10441 tttacctgtt tataagggtg aattagaaaa aggataccaa tttgatggtt gggaaatttc
    10501 tggtttcgaa ggtaaaaaag acgctggcta tgttattaat ctatcaaaag atacctttat
    10561 aaaacctgta ttcaagaaaa tagaggagaa aaaggaggaa gagaataaac ctacttttga
    10621 tgtatcgaaa aagaaagata acccacaagt aaatcatagt caattaaatg aaagtcacag
    10681 aaaagaggat ttacaaagag aagatcattc acaaaaatct gattcaacta aggatgttac
    10741 agctacagtt cttgataaaa acaatatcag tagtaaatca actactaaca atcctaataa
    10801 gttgccaaaa actggaacag caagcggagc ccagacacta ttagctgccg gaataatgtt
    10861 tatagtagga atttttcttg gattgaagaa aaaaaatcaa gattaagaca aaagctatag
    10921 aaaaaaatgg tttatgtact gagattagat agtgaggtga tgacatagtt ttgtgaaaac
    10981 agccatttat aactcaatta tttagtttac ttcactattg atactatttg gagttattaa
    11041 tggacttagt ttagataact aatgaattga ttgaaagggt tagtattgac aatattggtc
    11101 atattgatta gaaaatagag tctatcaaaa tttaaaggct aatagaggtg atgagacaat
    11161 ttcaaggaat taagtagcgt ttggttgctt aattcctttt tatttggaag gaagtttttc
    11221 gtaaccgccc aataacgaag tctattggac ggttacgata tgatcactga cttcgtcagt
    11281 cttatctaca acctcaaaac tgtgttttga gcaacctgcg gctagcttcc tagtttactc
    11341 tttg
//
LOCUS       DAVLZG010000062        10767 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLZG010000062 DAVLZG010000000
VERSION     DAVLZG010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.062"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(50..1366)
                     /locus_tag="VYO72_001730"
     CDS             complement(50..1366)
                     /locus_tag="VYO72_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1708056.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(1457..1545)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(1709..4045)
                     /locus_tag="VYO72_001731"
     CDS             complement(1709..4045)
                     /locus_tag="VYO72_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1708057.1"
                     /translation="MNKKILETLELDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKVKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYVEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(4149..4697)
                     /locus_tag="VYO72_001732"
     CDS             complement(4149..4697)
                     /locus_tag="VYO72_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1708058.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(4694..4996)
                     /gene="zapA"
                     /locus_tag="VYO72_001733"
     CDS             complement(4694..4996)
                     /gene="zapA"
                     /locus_tag="VYO72_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1708059.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            5083..5964
                     /locus_tag="VYO72_001734"
     CDS             5083..5964
                     /locus_tag="VYO72_001734"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1708060.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFDYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            5968..6582
                     /gene="lepB"
                     /locus_tag="VYO72_001735"
     CDS             5968..6582
                     /gene="lepB"
                     /locus_tag="VYO72_001735"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1708061.1"
                     /translation="MNSLKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKLLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            6662..6784
                     /locus_tag="VYO72_001736"
     CDS             6662..6784
                     /locus_tag="VYO72_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV1708062.1"
                     /translation="MKIKEQTRKLAVGCLKQWFEVVDRTDEVSSKYCFEVADGS"
     gene            6861..9227
                     /locus_tag="VYO72_001737"
     CDS             6861..9227
                     /locus_tag="VYO72_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1708063.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLTNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(9275..10558)
                     /locus_tag="VYO72_001738"
     CDS             complement(9275..10558)
                     /locus_tag="VYO72_001738"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1708064.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT         3085 a         2431 c         2187 g         3064 t
ORIGIN      
        1 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgttaa
       61 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
      121 gcagagccat caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa
      181 atcctcctaa caagaccatg agcacaaaaa acacacggta gagccagata aagcgagccc
      241 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
      301 caaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
      361 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
      421 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
      481 tcaaaccttg ctctactggt tcatttgtct tggcagctgc aataggagca gaacccagac
      541 cagattcgtt tgagaacaca ccacgcgcca caccattttg aatagccatc cgaacgctag
      601 caccagcaaa tccacctacc gcagcaaggg gactaaaagc tgaggtaaag actaaagcga
      661 ttgtgccagg gatttttccg atattaaaga aaataactgt aagagttcct aagatataaa
      721 tgagggccat aaaaggaaca acagtagttg aaaccttaga aatagacttg agtccaccaa
      781 agactgcaat cgctacaaag acagacaaga cgagagctgt gatggctggc gaaatcgtcg
      841 ttgtattttg gatagattct gtaatcgagt tgacttgggt gaaggttccg attcccaaga
      901 gagcaaccaa tactcctgct actgcaaaca aaacagcaag tggtcgccac ttttctccca
      961 tccctagaag gatatagtgc atgggacctc ccgctactgc accatggtcg tccttggtgc
     1021 ggtatttgat ggccaagagt ccttccgcat acttggtagc cattccaaag aaagccgcca
     1081 tccacatcca aaatagagct cctggtccac caaccttgat agccgtcgca actcctatga
     1141 tatttcctgt tccaacagtt gatgccaagg ctgtacacag agctgcaaaa ctggatacat
     1201 caccatgtcc cttatcctgg ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct
     1261 gcaagagtcc tagccgcatg gttaggtaaa tccctgttcc gaccaataaa atcaagaggg
     1321 gcggtcccca agcaaaagca tcgattgatt taagcaattc taacatttcc ttctcctatc
     1381 gtttcaaccc caaaagaaag agcacatgca agatacatgt actctggaat gcttagataa
     1441 atgctaaaaa gcggtctatc ctagctctgt ccttttacct gagagtttga gcagttgcct
     1501 gccttgcccc ttcggtgcct ttacggtctc tccagagttc cgtccattta cagtcatgga
     1561 aaatcaaacg attccccact tctattaaac ttcattcggt gttggtattt aattgattct
     1621 aattttacaa aaaatgttgg cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag
     1681 tttttacttt ataaagtcca gaatactgct atcctttaaa agtgacaata gtcgcaccac
     1741 tgcctccagc attttgtggg gcatagccga aactcttgac atgtttgttt ctttgcaagt
     1801 atttggtaac tccttcacgg atgactcctg ttccgatacc atggatgata tcaacttgag
     1861 ccatattgtt aagcaaggct tggtcgatga aggtatctag ctcattcatg gcttctacat
     1921 agcgcttgcc tcgaagatcc agtctagctt gaggtcctcg cccagaagtt cgtttcacaa
     1981 cattgacctg tttcttcttg actggttttt cttgctgggc ttgaacaaga tcaaactctt
     2041 tctcttccaa ggtcatctta atcaagccaa cttgggcttc ccagcgaccg tccttgagtt
     2101 gactggtcaa ggtaccacgc tgaccataac tgagaaccac gatatcatct cccacctttg
     2161 gagctcgttt tttcttggcc ttttgaagga ccttattttt agacaagtcc actttttcag
     2221 gagccaattt tttcaacttg accttggctt caatgatttc gtggggcttg agttgggatt
     2281 tactgtggag atttttgaga atctggtcac tttcacttaa ggccatatcc acaatctcag
     2341 cagcctgttc acgcgccttg ttaagctcgg tttccttttc acgattaagc tcgttgtaga
     2401 gtttttttag cgcacggttc atcttgagat tttcttgctc cacctcacgg atattgtcca
     2461 aacgtttgcg gctttccagc gtctgctctt ctaattgctc aatgatacga ttgacgtcat
     2521 tgtcctgatc gatctgctga ctggcatctc ctacgataac ttcagatagg cctagacgtt
     2581 tggcaatttc aaaggcatta cttcggccag gaacaccctg cataaagcga taggtcgggc
     2641 gaagagttgc agtatcaaac tccatactgg cattttgcac aaaggctgtc tcaataccgt
     2701 aggccttgag ttctggatag tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt
     2761 cctccagaat agccatggca agggctgctc cctcttgggg atcagtacca gcccccaact
     2821 catccaaaag taagagtgaa tgttggttga ccttgccaag aatatccacg atattggtca
     2881 tatggctaga gaaggtagac aagctctgct caatagactg ctcatctcca atatcagcaa
     2941 agatttcttc aaaaatacca acacgacttc ccttgtctgc taaaatcggc aatcctgact
     3001 gggccatgac ctgtgtcaag cccagagttt tgagcatgat ggtcttccca cctgtattgg
     3061 gacctgtaat gacaatagct gttaaatctt gaccaaaata gacatcattt gcgacggcat
     3121 ttttgaccaa aggatggcag acatggagca gttgaatctc ttgattttct gacagctgag
     3181 gcacgactgc ttgtctttct tggataaatc gaaccttggc acgaatcaag tccagatgac
     3241 cgataatcca agcgtcatta gcaatctcag ccgcatgagg gcggacacgc tcagaaattt
     3301 cttggagaat gcgaagcatt tcatagcgct catctgctcg cagactagca atttcttcgc
     3361 tcagtttgac tacctcacgt ggttcgatat agacggtgtt tccactagca gaaatatcat
     3421 gaacgacacc tgcaatctta ttgcggtagg tgtttttgac tggtaaaacc tgacggccat
     3481 ttctgctagc aacaattcct tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta
     3541 aaacatcgcg tacctgactc tcgctatcat gtatttttcg acggattcgc gccaattctt
     3601 cactggcaaa attttcaatg aaacccgcat cattaaaggc ctgaagattt ccttgtaatt
     3661 gcggaaaatc atgtaatttc tcaaaccaaa gggctaattc ttccaagctg acattttcca
     3721 gattggcgta aaaactttga agttctcggc tggtaagaag cacgcgtttc aagagtagga
     3781 actcctcgat attgagatcc gctcccatct ccaacctctt gcagactcct gcaatttcct
     3841 tagttgagag aatagtaaaa tgcggttgct cgacgaaaag agcctgcatt tctttcatct
     3901 cagcaaaagc ctgtttgatt ttatctgctt tggcagtcgg agccagctgt ctcaattgct
     3961 ccaagccctg ctcggtcaac aaatgaggct caaacaaggc cttgacctta tcgagctcta
     4021 atgtttctaa tattttctta ttcatcttta tttccttgtc tttgaatgtc taggtgtggt
     4081 agctttttac attctgatag attcgagtca aatctgtaaa caaagggcta ggaaaactcc
     4141 tgcccttttt atccgattaa atttgtcacc cagatttgtt tgagccaact ggttgttatc
     4201 ggtatactct ggatgatgtg ttttgcgacg atactctttt caagaggatt ttgtataact
     4261 gccatgggga tggtcgccaa gattgtcaag gccatttgca agacaaataa ggtcaccaac
     4321 atggacaaga tacctgctga aacttggaac aacttaccac ccagtttttt gctaggaatc
     4381 aagtgtaaga gaagaccaag caaacgacca atgctataga caatcccaaa tacaagcaag
     4441 tagccgatac ctgcataaaa gaccttatcc agctgaaaga gttgatccga tgggaaaaag
     4501 aaagtcccct gaccttcctg cgaatttgca taagggagca ataaatggaa ttgctctcca
     4561 agccccttat aaaactggcc agccataaaa gccgatgcca tggctgaaat caggtaataa
     4621 acctgtaaga gcaggcctct ccgatagccg atataaaatc cccaaaccaa gaccaataga
     4681 agaaggaatg aaatcataag gaatcctcaa tcttgctctg ttcttgctta caagtcacaa
     4741 gcttgtgacg gagttcttct agctcttgct ccttatcgtc aaattcaatc tcacggctga
     4801 gctgagttga taaacagttg actgccaaca aaagagcgat tgtttcatca tctgcgctag
     4861 gcatttgttc tttaattgct tggtattttt ctgtcgcaac cttagcgatt tcctccataa
     4921 aaaggttatc atgttcgctt gtcaaggtta acgatttttt cccgaatgta aatttgaatc
     4981 gatttagatt tgccataaaa ttcacctcac gatattatac caaaattcgc taattttgtc
     5041 agtttttaca aattttactg cttttgtggt acaatagaaa ctatggcaag tatcacactc
     5101 acaccaagcg aaaaggatat tcaggctttt cttgaacact atcaaaccag tctggctcct
     5161 agcaagaatc cctatatccg ctactttttg aaactacctc aagcaacggt ttctatctat
     5221 acttctggaa aaatcttgct tcagggtgaa ggggctgaaa aatacgccag tttctttgac
     5281 tatcaagctg tagagcaaac cagcggacaa aatcttcctt taattgggac agatgaggtg
     5341 ggaaatggtt cctactttgg tgggcttgca gttgtggctg cctttgtcac acctgaccag
     5401 cacgactttt tacgaaaact cggtgtgggg gattctaaga ctctgaccga ccaaaagatc
     5461 cgtcagattg ctcctattct caaggaaaaa atccagcacc aggcactcct tctctcaccc
     5521 agcaagtaca acgaggtcat cggagaccgc tacaatgctg tttcggttaa ggttgccctc
     5581 cataatcagg ctatctatct cctccttcaa aaaggtgttc agcctgagaa aattgtgatt
     5641 gatgccttta ccagtgctaa aaattatgac aagtacttgg cacaagaggc caatcgtttc
     5701 agcaatccta tcagcttaga agaaaaggct gagggcaaat acttggctgt cgcagtttct
     5761 tctgtcattg cgcgtgatct ctttctggaa aatcttgaaa atttgggacg agaactgggt
     5821 tatcagcttc caagtggagc tggaacggct tctgacaagg tggctagcca gattttgcaa
     5881 gcctatggta tgcagggact caacttctgc gccaaattgc actttaaaaa cactgaaaaa
     5941 gcgaaaaaac gcttagaaag gtaagttatg aattcactta aaaatttctt aaaagagtgg
     6001 ggattgttcc tcctaattct gtcattacta gctttaagtc gtatcttttt ttggagcaat
     6061 gttcgcgtag aaggacattc catggatccg accctagcgg atggcgaaat tctcttcgtt
     6121 gttaagctcc tccctattga ccgttttgat atcgtggtgg cccatgagga agatggcaat
     6181 aaggacattg tcaaacgtgt catcggaatg cctggcgata ccattcgtta cgaaaatgat
     6241 aaactttaca tcaatgacaa agaaacggac gagccttatc tagcagacta tatcaaacgc
     6301 ttcaaggatg acaaactcca aagcacttac tcaggcaagg gctttgaagg aaataaagga
     6361 actttcttta gaagtatcgc tcaaaaagcc caagccttca cagttgatgt caactacaac
     6421 accaacttta gctttactgt tccagaagga gaataccttc tcctcggaga tgaccgcttg
     6481 gtttcgagcg acagccgcca cgtaggtacc ttcaaagcaa aagatatcac aggggaagct
     6541 aaattccgct tctggccaat cacccgtatc ggaacatttt aagagaccta agaggccgag
     6601 aatcacaaat ctcagcctct tcttctatcg tgagaagtga ttgtttattg acaaatactc
     6661 aatgaaaatc aaagaacaaa ctaggaagct agccgtaggc tgcttaaaac agtggtttga
     6721 ggttgtggat agaactgacg aagtcagctc aaaatactgt tttgaggttg cagatggaag
     6781 ctgacgtggt ttgaagatat tttcgaagag tataaaataa aaacaatccc aactctcacc
     6841 tattcatgca aaggaatttt atggaagttt atttttcagg aaccattgaa cggattattt
     6901 ttgaaaatcc cagcaatttt tatcgcatcc tcctcctaga aatcgacgat acggacgcag
     6961 aggattttga tgattttgaa atcattgtca caggaaccat ggctgatgta attgagggcg
     7021 aagactatac tttttggggg caaattgtcc agcactccaa gtatggagaa caactgcaaa
     7081 tcagtcgtta tgatcgcgca aaaccaacta gtaagggatt ggtcaagtac ttttcaagta
     7141 gccatttcaa ggggattggt ctcaagacag ctcagaaaat cgtagatacc tatggcgaaa
     7201 ataccattga tgaaattttg caacacccag aaaagttaga aggcatcgca ggactctctg
     7261 ccaaaaatcg cgaggctttc gtctccactc tccgtctcaa ctacggaacg gagatggttt
     7321 tggccaaact agccaactac ggcattccca acaaactagc ctttcagatt caagactttt
     7381 acaaggaaga aacccttgat gtggttgaaa attatcccta ccagctggtt gaggatatca
     7441 agggtttggg ctttacaatt gctgaccaac tagctgagga actaggcatc gaaagtcagg
     7501 ctcctgaacg cttccgcgcc ggtctagttc acagtctttt tcaggcctgt atggaaacag
     7561 gagacaccta tgttgaagca cgggatttgc tggaacaaac ccttactctc cttgagtctt
     7621 cccgtcccgt agaactagac cccagccaag ttgcccaaga gctctcctac ctgatcgaag
     7681 aagacaaggt tcagcagatt gataccaaga tctttgacaa cagcctcttt ttcgctgagg
     7741 aaggtatccg cagtcacttg attcgtatcc ttgaaaaagg agaacagaag agacaagatt
     7801 tagaaactat tcaaaagcat atcactactg tcgagcaaga actggggatt gagtatgata
     7861 acattcaaaa acaagctatt tgtgacgcta tccagaacaa ggtctttatc ctgacaggtg
     7921 ggcctggtac tggtaagaca actgttatca atggaatcat cgctgtttat gcccttttag
     7981 aaggacttga cttcaggaag aaaagcaatc tgcccattct tcttgctgct ccaactggtc
     8041 gagctgctcg tcgcatgaat gaattgacag gtttgcctag cgcgaccata catcgccact
     8101 tgggaatgac aggtgacgat gataccagtc atctggaaga ttacctagat gctgacttta
     8161 tcatcgtgga tgaattctct atggtagata cttggctgac caatcaactc ttctccaata
     8221 tctcttctaa cagtaagatc ctcatcgtag gtgacagtga tcagctacct tctgtcagtc
     8281 ctggacaggt tctagcggat ctgcttcata ttcctttgat tcctcagact cgcttggaaa
     8341 aaatttatcg acaaagcaaa gaatcaacca tcgtcaccct agctagtcag attcgacagg
     8401 gcatcttgcc agctgatttc acccaaaaaa aagctgaccg ttcctacttt gaaattgcta
     8461 gtggccatat tcctgccacc attgaaaaaa tcttaggtgt cgccctcaga aatggtattc
     8521 ctgcccgtga tatccaagtt ctggctccta tgtaccgagg gacggcaggg attgatgcta
     8581 tcaatcagct catgcaagac ctgctcaatc ccccacaaaa agatcaactc agttttgaag
     8641 ctcctcagtg ccactatcgt aagagagaca aggtcattca tttggttaac gatgctgaaa
     8701 tcaatgtctt taatggggat ttaggagcta tcacagacct gattcctggt aaatacaccg
     8761 aatcgaaaca agacgagatt gtcattgatt ttgatggtaa tgaagtctct tacccccgta
     8821 acgaatggta caagattcgc ttggcctatg ccatgagtat tcataagtct cagggaagtg
     8881 agttcccagt tgtcatccta ccgattacta gtgctagccg acgtatgctg gagcgaaatc
     8941 tcatctacac agccattaca cgtgccaaaa gcaaactcat cttactaggc gaattacaag
     9001 ccttcgacta tgctacccaa cacatcggaa ctgcccgaaa aacctatctg attgaacgct
     9061 tcagtgatct actggagaat gttgaagaaa agcaacaagc tgtctctgaa acagtcacat
     9121 caagtgcctc tgaacaatcc tacatcctaa ccgaagaaaa ctgggacagc attccagcca
     9181 tgattgggat tacagacaca gacctcaaag agatttttgg aaaatagtac atcagaaaac
     9241 ccaccaattc aggtgggttt tctgtttatt aagattattt tactgttgct gtgcttgtga
     9301 tcaattcaac agcttttttg atagtgatat catgtttcaa catgtcagct gaaagcaagt
     9361 tttgaacttg tgcaacttcc atgttgtagt ctgctgccaa ttgctcaact tctttttgga
     9421 tttcttcttc tgaagcatca aatccttcag ctttggcaac tgcttcgata acaaggttag
     9481 tcttagtacg tgactcagct tctgcttggt attggttgtg aaggtcttct tgagtagttc
     9541 cagtgatttg gaagtacatg tcagggttga tcccttgacg ttgcaagttc ccaaggaatt
     9601 catttactga acggtgaact tcttcatgga tcatttcttc tggaagttct acgatttcag
     9661 cgttttctac agctgtatca attgctgcac cttcaactgc atctttgtaa gcttcttctt
     9721 tagcagcagc caattctttg cggtattttt ctttcaagtc agcaagtgtt tcaacttctt
     9781 catcaatgtc ttttgcaagt tcatcgtcaa gagctggaac ttctttagct tttacttcgt
     9841 ggatagttgt cacgaattta gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg
     9901 ggaatgttac gataacatca acggtttcgc cagctgagtg acctaccaat tggtcttcga
     9961 aaccagggat gaattgacct gaaccaagtc caagtgagaa gttttcacct tttccaccgt
    10021 caaattcaac accgtcgata gaaccaacga agtcgatcac aacagtgtcg ccgttttcag
    10081 cagcagcttc cttgataacc aattcagcca gattgttgcg ttcgcgttcg atacgctctt
    10141 caacatcagc gtcagttact tctttttcta catcaactga tacttcaagg tttttgtagt
    10201 cacccaattt tacttcaggt tttgtaacga cttcagcagc gataacccag tcttgacctt
    10261 tttccattga agttacgtca atttttggtt gggcaaccac ttcaagacca gcttctttta
    10321 cagctgcttc ataagcgttt ggcaaaagag cgttcataac gtcttggtaa agtgattctt
    10381 caccaaattt tttgtcgaag ataggacgtg gaaggtgacc tttacggaaa cctggaacat
    10441 taagagattt cttcactgac ttgaagacac ggtccaattc tggtttgatt tggtcttgag
    10501 agatagtgaa agtcaagaca ccacggtttg tttctttgtt ttcaaatgat acagacattc
    10561 tgtcatttct ccttaaaatt ttttaaatac agtctattat aacattttct ataaataaaa
    10621 tctagactaa tgcagccaat tatagacaac aagccttttt cctaactaaa acactcataa
    10681 agtatagaca attttagact actttggata tcttttggtt agtcattttc caaaactaat
    10741 ttatctaatt tttcagttat atagtag
//
LOCUS       DAVLZG010000063        10617 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLZG010000063 DAVLZG010000000
VERSION     DAVLZG010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.063"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(135..1559)
                     /locus_tag="VYO72_001739"
     CDS             complement(135..1559)
                     /locus_tag="VYO72_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1708065.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVTWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2104..4383)
                     /gene="pulA"
                     /locus_tag="VYO72_001740"
     CDS             complement(2104..4383)
                     /gene="pulA"
                     /locus_tag="VYO72_001740"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1708066.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4495..6453)
                     /gene="ligA"
                     /locus_tag="VYO72_001741"
     CDS             complement(4495..6453)
                     /gene="ligA"
                     /locus_tag="VYO72_001741"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1708067.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6546..7724)
                     /locus_tag="VYO72_001742"
     CDS             complement(6546..7724)
                     /locus_tag="VYO72_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1708068.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7804..8667)
                     /locus_tag="VYO72_001743"
     CDS             complement(7804..8667)
                     /locus_tag="VYO72_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1708069.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISSHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8670..10571)
                     /locus_tag="VYO72_001744"
     CDS             complement(8670..10571)
                     /locus_tag="VYO72_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1708070.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3181 a         2349 c         1901 g         3186 t
ORIGIN      
        1 atattttaga agtagagctg tactattcta gtttcaatat actataatac caaaaagttc
       61 gtattttttc tataattatt attattttat agcaaaaaaa taaaaccagg aaaacaattt
      121 cctgatttta cacgttattt cacatcaaaa acaatggatt tgacatttgt catcgcttca
      181 atgctatatt taattccttg cactccagct ccagaacctt tgacaccaag gaatgggaaa
      241 ttatctggac cacgctgggt tttattatta atgtggactg tacctacttc aagtttttca
      301 gcaatttcaa aggctttttt gaaatcattt gtaaagactg atgattgaag gccgaattca
      361 gattcgttgg caaaggcaat agcttcctct acactagcca cacgaatgat tggtaaaaca
      421 ggaccaaatg gctcttccca tgtcactttc atatcttttg taacttggtc aaaaagcact
      481 ggccagagga gattgccctc acgtttgatt ggtgtaagag cctgagcctc tttttcttgt
      541 gcatcctcaa tcaagcccca aatgaagtcg gctgaagcat tgtcaataac aggtgtaata
      601 tcagcattgt caaatggatc accaactgtt aatttagaaa cttcttcctg aagcaaagta
      661 gctaatttat ctgctacact ttcgagaaca atgacacgtt taatggccgt gcaacgttgt
      721 cctgagtagc taaaggctcc cgcaacaatt tgcttggcag catgttccaa atctgcatct
      781 tctagtacaa gagctgcatc tttcccacca agttccaaca tgataggacg cataccagct
      841 aaacgaccaa tacgttctcc aataggagtt gaacctgtaa agttgatgaa gttgacttct
      901 ttgtgctcaa tgatataatc cccaatttct gaaccacgac ctgtaatggt gttgaaaaca
      961 cctgccggaa tccctgcttc ttcaaatgct ttagccaaca agagtccaga aatggaacct
     1021 tgtgttggtg gcttcaacat gaccacattc cctgcaatca aggcaggtgc aattttagaa
     1081 gcagataaat taactggata attaaaggga gcaatcgcta gcacgatacc aactggttca
     1141 cgacggacaa cagccagttt gtttttactt gctgcctcaa aaccaccacc ttccattgct
     1201 tgtccagtga tacggagacc ttcctcagca gcataacgaa tcaagtctgc tgtacgcact
     1261 acttctccaa ttgctgcttt aatccctttt gctacttctt tggcaaggat agtaccaatt
     1321 ttttccttat cgcgttctaa aatagctgct gttttatgca aataagccgc acgttcaatt
     1381 gctgataaag ctcgccatgc tggcagggct gcacgcgcag cttgcatagc ctcatcagct
     1441 tcagtctgag tcatggctgg aactgtaccc aattcttctt gattgattgg tgaataaatc
     1501 gtaatttctt gttcagatga tttccatttt ccatttacta aattctgata tcttgtcaaa
     1561 ttcttgtcct cctgaaaatg attaagatat attttaccaa attttcagaa aatcacaacc
     1621 ctttttgcaa aatttttgag attattttca caatcttgat ttttcaaagt atactcaata
     1681 aaaattaaaa aaatccacta cgtcaaggcg aggctaatgt ggtttgaaga aattttcgaa
     1741 gagcatgaat gagtatcatc tatagtaaaa taaaaaaact gaacaatttg gttggggaca
     1801 gccaaaccaa tttctcacaa tgtttcagaa acaagggtgt gctattccaa tttcagccta
     1861 ctataactgt catagattgc tgaaacaaag tctaggtaaa agtcttcata ataaaaagac
     1921 ctcctatcaa gtgttcaaaa actttgatag gaggtcttgt tttgtgaaaa tatttatcaa
     1981 attttctata caagtgagct gttagccagg ttctttctat tctttcaatt tcaatgaatg
     2041 gattttttac taatactcat aactgggaat ttgtctgtgt aaaaatagcg agatagatgg
     2101 tatttataaa acactcaaga cagctagact aatatcattt aaaacattat cttcttttga
     2161 gcgactgttg gttaccaaca tagctaaatt tcctgcattt tcaaattgat agggttctga
     2221 tttagcattc acaactacca agaggtgttc tttgccgtga acttcataga taaggcagcc
     2281 gctatgttca atcgcagaat gcacaaagac atgatggtaa atttcatcat agctagagta
     2341 agaaaaggca ccagtttttg tcttcaatcg gatgacttga cggataaact caatactgtc
     2401 ttgacgctca ttaatcaagt tccagttcac ttggttcaca ctgtcaggag cattatagct
     2461 attcatcgca cgctctctat catcatgggt caactcacca ttttcaccag tcgcaaccag
     2521 tttggtacga ccaaattctt gaccgatttc cataaaggcc atcccctgca tgagcagatt
     2581 catggctgtg gcagtttcga ccttgcgcat gatttgctct gaactttggt ctggatgaag
     2641 ggttgccaat aaatcgtgaa gattgtaatt gtcatgggct tctacatagt taagcacctg
     2701 atttggatgt gtatagcttc ctaattcacg acttcctagg attgctttag ctagaattgg
     2761 ctctgtcgca gcaccactga caaaacctga cttgatagca ccataaactt ctcccccttt
     2821 gacagcatcg cgctgattgt cattaaagaa accaatattt ggcatctggt aggcattgtc
     2881 cttcttggcc ttatcataag gggcaagacc tgttcccata tcccatcctt ctccatagag
     2941 gataatgttg gagtcgattt catccaagct ttgacgaatc atctgcatgg tcttgacatc
     3001 atgaatcccc atcaagtcaa aacggaagcc gtcaatatta tattcctgca cccagtatag
     3061 aagagaatca atcatatact tgcgaaacat ttcgtgttca ctggctgttt catttccaac
     3121 acccgttcca ttctggaagg taccatctgg attcatacga taatagtaat cagggactgt
     3181 tgtttggaat ggtgcatcaa caactgagaa ggtatggtta tagactacat ccataatgac
     3241 tccaataccc gcatcgtgat aagcttgaac catcaccttc aaatcacgaa tgacctgagc
     3301 tggatcatct ggattagttg aaaaactagt ttctggcgcg ttatagtttt gtggatcata
     3361 accccagttg taggttacat ttccatcctc atcgtattct ttatgacggt ctgcaattgg
     3421 ttgcaattga acataattgt agcccagctt cttgatgtaa tcaaaagcag ttgactggcc
     3481 gtattggtta actgttccag cctgagcagc acccaagaaa gttcctcgaa gatgttcatc
     3541 tacacccgat gtaggtgatt tagtcaaatc acgaatgtgc atttcacaga taactgcctt
     3601 acatggattt tccaagcgcc aagtagcctc cgaaccgtgc ttaacctcga agttttcaac
     3661 ttgcttttct acatggctca gaatagctga acgtttgcca tcagggctgg tcgcgattgt
     3721 ataaggatca cgtgtcagtg tttggtgatg agggaattgg acttgatact gataagtctt
     3781 acctaccaaa tcttcttcaa catccaaact ccagacaccg attgtattgt ccttatgatt
     3841 ataagagtag ctattgcctc ttttcatctc aaaagtcttc caaacgggtg catcattagc
     3901 agctgattca taaacgacaa cttgcacttc tgtcgctgta ggtgaccaga gagaaaaatg
     3961 agcctgattg tcctctacac ggcaacccaa ttctccttgg taaccccaat gatgatcaaa
     4021 actagcactg ttaatggcct tatcaaaggc aaaaggattt tgatttttat agaaaggact
     4081 ggcaatagca ggattttcag agtaataaat cctatcatcg ccttccaaaa tccagacctc
     4141 tgttaatagg ggatagtgat taaaacggat agaatattct ttactagttt gacctgtatg
     4201 aaccacaaaa ttcaagcttt ctataacatg tgaacttggg tgttcaaagc taaataaagc
     4261 tccaaaataa tcttctttgt aggttagcaa atcaattcgt tgatcctgac tttttacaaa
     4321 ggagcaagtg tcatattctc cattcttacg atggtaatga atgcgcatag ggtagttata
     4381 cattttttat ttttcctttt tactttgttt ctatttcact aataaatttt tgtcaatctc
     4441 gtctcaatta acagacatag tcatattctc taaactctgt ttttaaacga tccattacaa
     4501 actttctagc catgcctcat ctctgacctg gataccaagt tcttgtgctt tttgcagttt
     4561 acttccagcg tctgcaccta ccacgacgag gtcggtcttt ttagaaatac tacctgtcac
     4621 tttggcaccc agactttcga gtttactttt agcttctgag cgcttgagtc gttccaattt
     4681 tcctgtcaat accacggtca aacctgacaa ggccgcatcc gctactaccg tctgtccttt
     4741 atagtccaga ttgaccccag tttctttcaa ttctctgagc agaatttcag agccttctgt
     4801 cgcaaaataa gtctgaagac ttttggcaat cacgccacct agactttcaa tactagccac
     4861 ttcctctgaa tctgcctgag acagattttc aattgaatgg aaatattgaa gtaaaagctg
     4921 actaaccttg cttccgacat gacgaattcc caaaccaaat aagagcttct cggcagagtt
     4981 ttcctttgat gcttggatag cctgatacag tttagcagcg gacttttcct taaccccctc
     5041 taaaaggagg aaatcctctt cttgcaaacg ataaatatcc gccacatcct tgactaaatt
     5101 agcagcaaaa agcttctcaa caatagatgg accaaggcct gtaatattca tagcatcacg
     5161 agaagcaaag tgaatcaagc cttccatgat ttgagcaggg caacgcggat tgatacaacg
     5221 tagggccact tcatcttcaa agtgcaacaa gtcagagtta caacttggac agtttgtagg
     5281 gatatctagt ttttcttcag aaacccgttt ggactctacc acacgtaaaa cggcagggat
     5341 gatgtcacca gccttatata caatgaccgt atcgtctttt cggatatctt tttcagcaat
     5401 ataatctaca ttgtgcaggg tcgcacggct aacagtcgta ccggcaagtt gtactggtgt
     5461 tagattagca gttggagtta caacaccggt acggccaact gtccagtcaa ctgataagag
     5521 ttgagcttct ttttcttcgg cagggaactt gtaggctact gcccactttg gagccttaac
     5581 ggtaaaacca agttcttctt gacttgctag gtcgttgacc ttgattacca ctccatcaat
     5641 atcgtaaggc agattttccc gttcctgtcc tacttcttgg ataaaattcc agatttcatc
     5701 tatgttttca gccaagattc gcttaggatt gaccacaaaa cctagttgtt ctaggtactt
     5761 caaacccttt tcttggctat cacgagttga agggctggct tcttgataga gaaacgttgc
     5821 aagattacgc ttggcaacta ctgctgtatc caactgacgc agagttcctg ctgccgcatt
     5881 acgaggatta gcaaattcag gctctccatt ttcttggcgc acttggttaa cttggtcaaa
     5941 ggaagcgcgt ggcatgtaac attccccacg aactgtgata tctagttctt ctggcaaagt
     6001 caaagggatg tccttaacac gcttgaggtt ttctgtgata ttttcaccaa ttgaaccatc
     6061 tccacgtgtt accccagcaa ccaaaatccc cttttcataa gtcagcgaga tagataagcc
     6121 atcgattttc agctcacaaa tataggtcgg atgagccact tccttacgaa cacgcgcatc
     6181 aaaagcatct agctcctcac gtgaaaaagc atcctgcaaa ctataaagag gatactgatg
     6241 actgtatttt tcaaaaccat ctaaaacctt gccaccaaca cgatgagtcg gactgtctgc
     6301 tagcacttgc tctggataag cagtttctaa ctcgaccaac tcacggtaaa ggcggtcata
     6361 ctcactgtct gaaaccgagg gattatcgct ggtatagtac tcagtcgcat agcgattgag
     6421 caaagcgact aactcattca ttcttttatt cataagacca ttttaccata aaacaagccc
     6481 tcctcacaaa cgagaagggc ggaaaaaaca cttagtttga aattattttt gaaactcaag
     6541 caaccttata tcaatttttc aaaatgagtt cgaacataaa taaacgatat acaagacaag
     6601 atgataacac cacttccaat tatcaggaaa gaagagagat gtacacttgg caagactgtc
     6661 ataaatcctt ttgcaatagg cataaataga atagctaagg taaaaattgt actcagtact
     6721 cttccaagaa attcgctctc aaccttggtt tgtacttgag taaaaaagtg aatattaaaa
     6781 atcgtcataa acaattcaca aactaaattt ccagaaaagg aaagaaaagt tggaagtggt
     6841 aatcccatca taaaaactcc gacacctgtc aaagccagta aaatcaaaag attataaata
     6901 ttagctttaa ttttactagc tagaagagcc ccaatgatgg aaccaatagc ccccatagtt
     6961 aaaatacttg cataggctcc ttctgacccg taaagctgat tcgaaaaggg aagtagaaat
     7021 tcaaaagctg caaaaaagaa attaacgctg gaagctacca gcaaaaggaa gaaaatttct
     7081 tgctgatgcc agatatagtg taacccatcc ttgatatcta caaaaatatc tctcccagta
     7141 aaagcctttt tctcttgaac ttttgcttcc tcttttggaa ggaaagccac tagaacaaaa
     7201 gcaatgaaaa aagtcagcga gtctagcagt agcgtcatat ggagacttgc aaactgtaaa
     7261 acaaggaagg aaagaacagg agagctaaca cctacaacct gcaaaaccag ctctaggcga
     7321 gaattataga tcacaatctc atctttctcc accacttcag ttatgatagc tttattggct
     7381 gtgcgagaaa aggcaaaagc aatagcctgc acaatgttag caacaatcaa agcgccaatc
     7441 atccagctat cattccttat gaaagaaata gccagacaaa gaatcccaca aacaagatct
     7501 gccgtcatta aaatcttacg acgagaaaaa cggtctgaaa taactccgcc aaagggattg
     7561 acgagaatag atgtgacgag ctcagaaatc tgatacattc ctaaaactgt ctgtcctata
     7621 gtccccatag aagccaacca gacactattt ccataatcat agagcatatt tcccatttta
     7681 ttgatagccc cacggctaat caactgcact gcatagcgat tcatattaaa gctcctctca
     7741 aattttgaaa ctattgtatc aaaaccgaaa ggagcttttt attttttccc ttatttggga
     7801 aaattaactt ttgacaaatt tttcgtagtg ttcctgataa taggctactt gctctggaag
     7861 acctaacaca tcaaaaatat gtatggcctc ttgcatctgc ttacagcctt ctttacactg
     7921 tcctttttga tataaggcaa aaccttttaa ataatggaaa acattacgct cataaagctt
     7981 aatacctttg tcaataatct tctctgtata agcctcaaaa tagttggcat tataaaaaga
     8041 agaatgctct aaacaatgct ggtaacaatt gagggccaaa atcaacacta atctcttatg
     8101 gctactaatc tcttggtaaa attcctccct ctccataact tctctaccaa tccgagtgac
     8161 ataatccaca tcgtagaaac tatagaggtt accgaaaaga atcaactcat acatggtcca
     8221 ttcttctgtt ttgaagagat aatctgctac cttatccaaa tcatcctgct tcatatcata
     8281 actcgcatct ctttgacaaa tcagaccctg tagcaaaatc cagttcagct caaaataaag
     8341 gggagtcgtc gaactcttag acttttcaag ttgttctctt tgaagctttt gaaaacctgc
     8401 aatatcgttt gaatagtaaa gtgggataat ctgtgccatc atagacacat gttcatgatt
     8461 atgaaaattc cttgccttat ccatgaaatt ttcgattgtt acatgaatgt tatccaaaat
     8521 ctcaaagaaa cgggagactg ccaggtcaga ctccccaagc tcaaagcgag ataactgaga
     8581 ggtagagcag gattcgcctg ctgcttcctt caaagaataa tttccacttg ttcgaaattc
     8641 acgaaatact tttccaagat gttccatctt tacacctgct ctgataattc ttcccactca
     8701 agcatagctt cttcctgacg atggctgatt ttgtccagct cagcctgtaa ttccatgagt
     8761 ttgtcggcat cgtttgtttc caacatttgt tcagaaatgg cttggctttg actttctagc
     8821 tcttcaattt cagcttctag actttcgatt tgtcgcatga gtttgcgaac ttctttttga
     8881 ctttctttct gggcctgata gtcattgact ggacttgctt cctttgcttg attgctagtt
     8941 gaagcttcct cagtctgact catttctgct gttgctttct tctcaacata gtagtcgtaa
     9001 tctccaaggt agagagttga accattctca gacaattcca aaacatgagt tgccacacga
     9061 ttgataaagt aacgatcatg actgacaaaa agcaaggtac catcaaagtc aatcaaggca
     9121 ttttctagca cttccttact atcaatatcc aagtgattgg tcggctcatc cagaatcaaa
     9181 aagttattgt tttccataga caatttagct aaaagcaaac gagctttttc gccaccagat
     9241 agcatgccga ctgatttttt aacatcatct cctgagaaaa ggaaggctcc aagacggttg
     9301 cggatttcaa cttctggtgt caatttgaaa tcattccaga gttcatccag caccgtatta
     9361 cttggtgtca gcttgctttg ggtttggtca tagtaaccaa cctcaacatt agcgccaaag
     9421 cgcttttctc ccttgataaa cggaatttga tccacgattg atttgataaa ggttgatttt
     9481 ccgataccat tgggaccaac gatagcaaca gcattcatct tacgaaggtc taggttaatc
     9541 ggttgtgaca ggacttcccc atcatagcca acagccgcat tttcaacagt caaaacaaca
     9601 ttgcccgacg ttttttcaga ctggaaggtc atgttggctg ctttcttgcc agcttccggc
     9661 ttgtccaaac gctccatttt ttctagttgt ttacggcgag attgagcacg tttagtcgtt
     9721 gaagcacgaa ctagattgcg attgacaaag tcttccagag cagcgatttc cttctgttgc
     9781 ttttcatagt tttttgcctc agtagctagc ttttgctcct tcaactcgac aaaacgagag
     9841 taattcccca catagcgatc caaggaatgc ttggtcaaat ctagcgtaat tgtcgcaacc
     9901 ttgtccaaga aataacggtc gtggctgacg ataatgaggg caccgctata gtttaccaag
     9961 taattctcta gccaggagat ggtttcaata tccaagtggt tagttggctc gtccaagacc
    10021 aagagattgg gcttttcaag gagcatttta gctagagcca aacgagtatt ttgaccacct
    10081 gaaagttcag ctattttcat ctgccacata gactcgtcaa acttgaatcc attcaaaatc
    10141 gctcgaatat cagcttcata ggtaaagcca cctgcttggc gaaaattctc agataagcgg
    10201 tcataatctg acatcagttt atccaaatcc tcaccagact tttcacccat ctccagctcc
    10261 atctgacgca gttgtctctc cgtccgacgc aaatcattaa agacatgaag catttcatcg
    10321 tagatggtat tttcagactc aaaacggcta tcttgggcta ggtaagacag agaaatatct
    10381 tttttcttat tgatttctcc gctagttggc tcctcttctc caactaaaat cttcaaaaga
    10441 gtagacttac ctgcaccatt tttcccaaca agagcaatcc gatctcgttc atcaacctgc
    10501 aggttgatat tatcgaaaag aacctctcct gcaaaagaac gttcaatttt attagcttgt
    10561 aaaataatca taagagtagt atagcatgtt tccctaaggc attcaagata atcgtaa
//
LOCUS       DAVLZG010000064        10498 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLZG010000064 DAVLZG010000000
VERSION     DAVLZG010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.064"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            1..607
                     /locus_tag="VYO72_001745"
                     /pseudo
     CDS             1..607
                     /locus_tag="VYO72_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            573..953
                     /locus_tag="VYO72_001746"
     CDS             573..953
                     /locus_tag="VYO72_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1708071.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1091..2395)
                     /gene="eno"
                     /locus_tag="VYO72_001747"
     CDS             complement(1091..2395)
                     /gene="eno"
                     /locus_tag="VYO72_001747"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1708072.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2559..3005
                     /locus_tag="VYO72_001748"
     CDS             2559..3005
                     /locus_tag="VYO72_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1708073.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3002..4117)
                     /locus_tag="VYO72_001749"
     CDS             complement(3002..4117)
                     /locus_tag="VYO72_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1708074.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4126..4455)
                     /locus_tag="VYO72_001750"
     CDS             complement(4126..4455)
                     /locus_tag="VYO72_001750"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV1708075.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4400..4771)
                     /locus_tag="VYO72_001751"
     CDS             complement(4400..4771)
                     /locus_tag="VYO72_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1708076.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4830..6263)
                     /gene="glgA"
                     /locus_tag="VYO72_001752"
     CDS             complement(4830..6263)
                     /gene="glgA"
                     /locus_tag="VYO72_001752"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1708077.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHIHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWLAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6260..7399)
                     /gene="glgD"
                     /locus_tag="VYO72_001753"
     CDS             complement(6260..7399)
                     /gene="glgD"
                     /locus_tag="VYO72_001753"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1708078.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7389..8531)
                     /locus_tag="VYO72_001754"
     CDS             complement(7389..8531)
                     /locus_tag="VYO72_001754"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1708079.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8521..10449)
                     /gene="glgB"
                     /locus_tag="VYO72_001755"
     CDS             complement(8521..10449)
                     /gene="glgB"
                     /locus_tag="VYO72_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1708080.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPNVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLICIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3179 a         2313 c         1872 g         3134 t
ORIGIN      
        1 gcttctgaat ttggctgtca tccaactacc atccactata cgctcaaagc tatgggctac
       61 actcgaaaaa aagaaccaca cctactatga acaagaccca gaaaaagtag ccttatttct
      121 taagaatttt aatagtttaa agcacctagc acctgtttag attgacgaaa caggattcga
      181 tacttatttt tatcgagaat atggtcgctc attaaaaggt cagttaataa gaggtaaagt
      241 atctggaaga agatatcaga ggatttcttt ggttgcaggt ctaacaaatg gtgagttaat
      301 cgttccaatg acttacgaag agacgatgac gagcgacttt tttgaagctt ggtttcagaa
      361 gtttttctta ccaacattaa ccacaccatc ggttattatt atggataatg caagattcca
      421 tagaatgggt aagttagaac tcttgtgtga agagtttggg tataaacttt tacctcttcc
      481 tccctactca cctgagtaca atcctattga gaaaacatgg gctcatatca aaaagcacct
      541 caaaaaggta ttaccaagtt gcaatacctt ttatgaggct cttttgtctt gttcttgttt
      601 caattgacta tataaattgt ctaagcgaaa caaccgataa gaattggcac aaaagcgacc
      661 gtgtttttgt taccaataca ggaaaaacag ttcatagttc tatcttgagc aagtctctcc
      721 agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca tctgtcccct cacatcttca
      781 gacacaccac tattagcatc ttatcagaaa ataaaattcc tttaaaaaca atcacggaca
      841 gggttggtca ttccgactct gaagtcacta cttccatcta cacccacgtc acaaagaaca
      901 tgaaagatga agcaatcaat gtactggata aagttatgaa aaagattttt taaaaagttt
      961 tgcccctttt ttgtcctcta aatacaaaaa tagcccttcg gataaaatcc gaggggctag
     1021 aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg gttcgggata aaatagttca
     1081 ctgaactatt ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
     1141 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatacgg tctgtacgtg
     1201 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca gcgattgttg
     1261 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
     1321 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
     1381 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
     1441 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
     1501 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
     1561 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
     1621 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga
     1681 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
     1741 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
     1801 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
     1861 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
     1921 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
     1981 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
     2041 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
     2101 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
     2161 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
     2221 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
     2281 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
     2341 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
     2401 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
     2461 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
     2521 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
     2581 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgaacaaaga cgctatcttg
     2641 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
     2701 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
     2761 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
     2821 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
     2881 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
     2941 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
     3001 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
     3061 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
     3121 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
     3181 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
     3241 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
     3301 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaagg
     3361 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
     3421 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
     3481 gtagaccttt ttgattgcca aaagtgtaag tcgcaccttg atgaccacat aagggactca
     3541 cgacatctgc tagaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
     3601 aaacagaagc taagtttaat aaggattgat cggaagcagg caagacattt ccatccctat
     3661 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
     3721 caccaacacc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
     3781 caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
     3841 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
     3901 ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc
     3961 ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat
     4021 ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc
     4081 tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc
     4141 aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt
     4201 gagcatttct ttggaacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt
     4261 attgacccca tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca
     4321 tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt
     4381 taaaagacct tctttgactt caagctggtt ggcagtgaaa taggcaatac caagggattt
     4441 tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact aggatgccat
     4501 tcttttggag aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga
     4561 cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc
     4621 tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt tccgcctcat
     4681 gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat
     4741 ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat
     4801 cgtatgaagt catcatacga ttttatctat taattaacta aactatggta caagtcaagg
     4861 tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt
     4921 ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac
     4981 caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa
     5041 gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc
     5101 atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca
     5161 caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg
     5221 tctgggtaaa tctgagccaa ccatgagaaa gctccttcaa aggctggatc gccagttccc
     5281 aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca
     5341 aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca
     5401 ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc
     5461 tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc
     5521 ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc caaattacat
     5581 ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc
     5641 gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca
     5701 gcgtaacgtt caaggccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct
     5761 tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa
     5821 cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aatatggaga
     5881 agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca
     5941 aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg
     6001 tcaataaagt agaaggttac accatttaat actgttttct taattccaca atactgtctg
     6061 cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc
     6121 tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat
     6181 tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct
     6241 gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa
     6301 ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt
     6361 tgtccaagat agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca
     6421 ggctatcttt aaccaagcta tccttatgga catgaatatt acgtgataga acagaattag
     6481 ctacttgacc ttcaataata ctaccagagg caaactgaga agtgcttacc ttagatgtat
     6541 tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga
     6601 aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa
     6661 cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag
     6721 ccaaatcccg taaaacatag cgcaatttct ttggatgttc ttttttagct tcttcttcca
     6781 agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt
     6841 cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat
     6901 ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa actacagtga
     6961 taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa
     7021 catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct
     7081 gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat
     7141 agtaatgact aagaagggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata
     7201 ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa
     7261 ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa cttgctactg
     7321 gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag
     7381 aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt
     7441 acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg
     7501 gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg
     7561 acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca
     7621 tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag
     7681 tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag
     7741 gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca
     7801 tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt
     7861 ggaatgacat ttttcccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac
     7921 atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta
     7981 ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata
     8041 ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta
     8101 ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg atccccagac
     8161 aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg
     8221 tgactagtcc cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag
     8281 acacctgaat tgataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga
     8341 gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt
     8401 gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg
     8461 ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt
     8521 tcatttttca ttttctactc ctttttggtt tttatttgtg acggttttag tagatttcaa
     8581 gcgacgtttg attttccata cacttgctcc catagccggt agagtaaagg ttaaggtctg
     8641 ctcataatct ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac
     8701 gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag
     8761 tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga ttaacatttc
     8821 tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat
     8881 gatttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa
     8941 ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga
     9001 ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa
     9061 gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa
     9121 ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc
     9181 atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac
     9241 caggttaaag tcatatttac gatagatcgg atcttcttcg tagaaacgga ggatatcatt
     9301 catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt
     9361 aatcttggtc gcagacgaac tttcttctgc aatcatcatc acatttggat attctaactt
     9421 aataacctca ttcaagcgct gaaggaaata ataaccttca tagttgagat ttccgccatc
     9481 tttattaggt gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc
     9541 cacacgaata ccatccaaat gatagacatc aatccaatgc ttaatgcaag aaattaagaa
     9601 ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc
     9661 cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta aggcatcatc
     9721 gttgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca
     9781 ctcctcgaca aaatcttgaa actcctctgg tcggccataa gcatgctcta aagcgaagta
     9841 acccataagc tgataccccc aactcaagcc caaaggatgg gacatcaagg gcataaactc
     9901 aatatgagta tagttcattt caacgagata aggaatgagt tcatccttga gctgggcaaa
     9961 actataagga ctgccatcag aatttctttt ccatgatcca gcgtgaactt cataaatatt
    10021 gacaggacgc tcttcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccttcca
    10081 tttcttctca ggaagctctg ttaagattgc ccctgttcct ggacgagcct catacctgac
    10141 agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta
    10201 aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaaat catttcttac
    10261 cattggaatc tgattttcaa tccagttggt aaaatcacca accaagtgaa cagcctgagc
    10321 attaggtgcc caaacacgga aggtatagcc atgctctcca tttagttctt ccctatgtgc
    10381 tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct
    10441 attatccata tactcccctt ctcctgtaag cgttttctat gtttttatta tactacct
//
LOCUS       DAVLZG010000065        10297 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLZG010000065 DAVLZG010000000
VERSION     DAVLZG010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.065"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="VYO72_001756"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="VYO72_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1708081.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1317..2021
                     /locus_tag="VYO72_001757"
     CDS             1317..2021
                     /locus_tag="VYO72_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1708082.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="VYO72_001758"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="VYO72_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1708083.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="VYO72_001759"
     CDS             3365..4174
                     /locus_tag="VYO72_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1708084.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /locus_tag="VYO72_001760"
     CDS             4265..4507
                     /locus_tag="VYO72_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1708085.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="VYO72_001761"
     CDS             4509..4763
                     /locus_tag="VYO72_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1708086.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5505
                     /locus_tag="VYO72_001762"
     CDS             4810..5505
                     /locus_tag="VYO72_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV1708087.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(5854..6840)
                     /locus_tag="VYO72_001763"
     CDS             complement(5854..6840)
                     /locus_tag="VYO72_001763"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1708088.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7034..9502
                     /gene="gyrA"
                     /locus_tag="VYO72_001764"
     CDS             7034..9502
                     /gene="gyrA"
                     /locus_tag="VYO72_001764"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1708089.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9502..10245
                     /gene="srtA"
                     /locus_tag="VYO72_001765"
     CDS             9502..10245
                     /gene="srtA"
                     /locus_tag="VYO72_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1708090.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3197 a         1750 c         2293 g         3057 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggccccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg agtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cgcaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaaggtccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt cgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattaaag ctgagtaata acaatataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggttattt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgac tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttgaccattc tccctttaaa tgctattttt acagtgtttc gattaggacg tatcttccgc
     5101 ttagcaaggc tgacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaactag aaagaaaaat tagtagattc ttacgaacaa atggattgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgctaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actcaaagac gaattatcga gctaaagaat attaatagag
     5521 aaacaatctg aaaaaatcga agaactacat tgaatgataa aagacttagt tgaaaaaata
     5581 tcataaaggt gagacaaaat aaaacttgat tcgaggagaa atcaagtaag ttttgacaca
     5641 atagaacgca tattatcagg tataaaaact tgatactatg cgttttatag agaaataaaa
     5701 taaaatctga acaaatcaat taggaattta aagcatttta taacaacgtt ttagagtaat
     5761 ggggtgctat ttcaacttca acctactata atacagaaaa aaatacagaa aaaaacaact
     5821 ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc
     5881 tggatttttc catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt
     5941 ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac
     6001 aacagctggt tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga
     6061 aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac
     6121 tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac
     6181 accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc
     6241 ttcaagattt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg
     6301 ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc
     6361 ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa
     6421 accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa
     6481 gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt
     6541 tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac
     6601 aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt
     6661 gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg
     6721 aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga
     6781 tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat
     6841 tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt cattctatca
     6901 cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt
     6961 ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat
     7021 gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa
     7081 ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg
     7141 agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac
     7201 cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca
     7261 cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta
     7321 ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc
     7381 cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat
     7441 caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt
     7501 cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg cggttgggat
     7561 ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat
     7621 ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc
     7681 aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg
     7741 ttcgattgtc ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat
     7801 cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg
     7861 cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga
     7921 aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa
     7981 cctcttcaaa atgacccaaa tgcaaaccaa ttttggattc aatatgctcg ctatccaaaa
     8041 tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatattg agcaccaaaa
     8101 agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat
     8161 cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc
     8221 tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg
     8281 tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa
     8341 gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc
     8401 taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt
     8461 ttctgataaa cgccgtacag agttgatggt tggacagatc ttgagtctcg aggatgagga
     8521 cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt
     8581 ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt
     8641 gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt
     8701 cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg
     8761 gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagatg aaagtattca
     8821 gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg
     8881 tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct
     8941 caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttga cagaaggaga
     9001 tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt
     9061 tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac
     9121 agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg
     9181 atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat
     9241 gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg
     9301 ggatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa
     9361 tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc
     9421 tcagatagtg actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa
     9481 cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa
     9541 aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt
     9601 aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag
     9661 gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct
     9721 gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca
     9781 gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt
     9841 gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa
     9901 ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta
     9961 ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa
    10021 gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt
    10081 gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca
    10141 gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat
    10201 gaaattctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa
    10261 tcatggattt cactgatttt ttaagatttt cataaaa
//
LOCUS       DAVLZG010000066        10149 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLZG010000066 DAVLZG010000000
VERSION     DAVLZG010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.066"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(162..1925)
                     /locus_tag="VYO72_001766"
     CDS             complement(162..1925)
                     /locus_tag="VYO72_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1708091.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(1934..2524)
                     /locus_tag="VYO72_001767"
     CDS             complement(1934..2524)
                     /locus_tag="VYO72_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1708092.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VYO72_001768"
     CDS             complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VYO72_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1708093.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3190..3882)
                     /locus_tag="VYO72_001769"
     CDS             complement(3190..3882)
                     /locus_tag="VYO72_001769"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1708094.1"
                     /translation="MKIGIIAAMPEELAHLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(3899..4213)
                     /locus_tag="VYO72_001770"
     CDS             complement(3899..4213)
                     /locus_tag="VYO72_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1708095.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4225..4770)
                     /locus_tag="VYO72_001771"
     CDS             complement(4225..4770)
                     /locus_tag="VYO72_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1708096.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VYO72_001772"
     CDS             complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VYO72_001772"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1708097.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRCRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPRNQ"
     gene            6293..7093
                     /locus_tag="VYO72_001773"
     CDS             6293..7093
                     /locus_tag="VYO72_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1708098.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSIWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7188..8030
                     /locus_tag="VYO72_001774"
     CDS             7188..8030
                     /locus_tag="VYO72_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1708099.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYSLNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNTGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8030..8512
                     /locus_tag="VYO72_001775"
     CDS             8030..8512
                     /locus_tag="VYO72_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1708100.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8512..9132
                     /locus_tag="VYO72_001776"
     CDS             8512..9132
                     /locus_tag="VYO72_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1708101.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPADRILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9385..9480)
                     /locus_tag="VYO72_001777"
                     /pseudo
     CDS             complement(9385..9480)
                     /locus_tag="VYO72_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9893..10149
                     /locus_tag="VYO72_001778"
                     /pseudo
     CDS             9893..10149
                     /locus_tag="VYO72_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3121 a         2144 c         1769 g         3115 t
ORIGIN      
        1 ataagttata gtgtagcatt ccaacttcaa agcactataa agtaaattga aacaagaaca
       61 atacaaacaa ttctcgtaaa cggattgcaa ccacaaaaaa gcaagcattc acaagaatac
      121 ttacctatca tgggaggaac aaccgttcct cttttttatt actaaaattc aaagaattcc
      181 aatgcttttt tcaagagcaa atccgtatat tctggatctt cttgggctac ttctatttcc
      241 cgctgaactt tttccaaatc atctgtaatc actccatcta ctcctaagtg aagagatttg
      301 ctgatagctt ctgaatcatt gacagtccag acataaagtt tctgatccgt tgtccatagt
      361 ttgcttacaa aatattcatc caaggttgag tactccatag tatatcctgt cgctcttgtt
      421 ttaggaaaga cagaattgta gggcatgatg aaataaactg gcagttcggc atcatactgt
      481 cttacttttt cgacaacatg gtagtctaaa gactggattt gatgtccata aatcttgagc
      541 tttgcagcat aacgggctaa aaagcggttc atcatgtctg gactatcttt tttactggtt
      601 ttaatttcaa ttagtaattt ttgaccaagt tcgttggctc gactgagata atcttcaaag
      661 cttgaaattt tagtctggta gccattttca aaaatatcaa tccctttaag ctcctccaag
      721 tttaagtctt gaggactttt attgatacct gctagatttt tcaagttagc atcatgcatc
      781 atgacaaact gcccatcttt tgtttcctgc acgtccgtct ccaccaagtc tggtttgagt
      841 tgtgctgtag tttccaagga ctctactgta ttttgaatcc catttgcatt ggaaacccct
      901 cggtgagaaa taagttgagg tagatgaacc atgggagcct ccagataaat ataaccttct
      961 aaggcaaaga aaagactggc acaagtcatg acaccccatc gcacgatgtg atctttttct
     1021 ctcctaggaa gcatatccag ctcctttcct gtcaaaaatg aaacaaattt aaccaaaaaa
     1081 taagtcagag ccatataata gagattttta atcacgacaa aattcaaaat accaagaatc
     1141 agagactctc tctgagtgat atcatctacc aaagtttgag ccaataataa agggatcaaa
     1201 ggaagataaa ataataaatg tgctttgagc aagatgtaaa ataaattcca agcataaaaa
     1261 gtaactctct tcttggtttt ctccaagcta aacatcactg cttctcgaac agtcagctga
     1321 tcatatacaa tcttcggaag ggcaaacatc aatctgacag agacatagag aaagataaga
     1381 gatagaagta ggatgctcag ccaccacatc caatatctat cttctaaata agcttggata
     1441 aactctggaa tgacgatttt attaagataa taaatcttca gcattttccg tataaaagga
     1501 aacagcatag ctatatagaa aaagataaac aaggctttag cgcaagttag ctttttcata
     1561 aatccaaaac tttcatggaa aaccttgcgg atatactcaa ttagccttcg cttttcatta
     1621 tagaggagat gacgagcacc aataaagagg agtcctattt gaaaataagc aaccagaagg
     1681 ttaattacaa tcaaggctaa aaaagctaga ctaatcaatg gagaatgagt aaggatggct
     1741 aagacattgt tataggaaat aaaaagataa cctgtctgat ctaataagaa gctagccaac
     1801 catgaattga atggtaccca caaatactcc actatcataa aaatcaagaa aaatagaaag
     1861 aggattttat caagattgag gtaaatctgt ttaagaccca attttttagg tttttcaggt
     1921 ttcataggca ctcctagtca aataattgag acaagtccaa gccaccaaaa ggattgtttg
     1981 ataagctact ttctgtctct aacaattccc tagcttgatc cgactctaag aaggattcgt
     2041 aaacacgcgc cgtcatccga gcatcctcta aactattatg agactgacct tgaaatccaa
     2101 gaaatgaggc aacagtttgc aatttgagat tggcaatacc atgtaaatct gaactccgac
     2161 gttcaaaagc ttcatcatac aaatccacct tgtactgttg gctatagtct aaaccatgct
     2221 ctgctaaaat aggtaaatca cttttagcag cattgtagcc tatcatcagc aaagaaccca
     2281 caaactcttg gaattcttct aagactttct caactggagg agcatctttt aaggtctcag
     2341 ctgtaatccc ggtcaaacca ttgataaagc tttttagagg gacgctggta tgaacatagg
     2401 aatcataggc atcgatttcc cgaccatctc taaaacgcac tgccgatact tgaatcaagt
     2461 gtgtttgtcc ttcgtgctga ttaaattcta agtcaaaagc aatgtaatct tctaatcgtt
     2521 ccattctgta cctctcctct actgtctctg ttctaatcaa ctatactatt cacaaacaaa
     2581 agaagccatc aggttagcat ttaacctaaa cagctccttg attatcctcc aaataaacga
     2641 gcaaaaaagc cttttttagt ggattggact tcttcttttg cttggtccag ctctagctta
     2701 agattttctt gatccttcat ggcttgaagg gtcaattgtt gttgctgatc taattgtttg
     2761 tctttctcag caatctgacg gtctttgata cgcatctgct cgtctttttc tgataactga
     2821 cgatccttgg cttttaattg ttcataaaga cgaagaattt ctgcattctt ctcatccact
     2881 agaatctcca tcagttcacg ttgtttgaca tcttcactga caggttcatc ttcaaaaatc
     2941 gtttttttat agatttcttc tagcttaatc aagccacttc tggtaacaac tgttacccct
     3001 ttgtcatttt tatctgtgtc ttcttctggt aattctttga cacggttatt gattgcttgg
     3061 cgagataatc ctaagacctc tgcaatctca ctgacggtca tttcaatact cataatatcc
     3121 tctgaaacgt tttctagctt ttctttactt aaatcttatc ataagctaga aaaactgtca
     3181 aatttccgct taatctaaag ccttcaaaaa ggccaacaag acttgggcag agcgacgtcc
     3241 agcttcgata ataaactcat caaaaaagat gtttgcttca tggttggcat tgtcactcat
     3301 agctctgatg actaagactg ggagattgag ggcatgcgct gcttgagcaa tagctgcccc
     3361 ctccatctcc acggctaaaa cttctgggaa atgggactta atcgcttcta tcttgtcatt
     3421 tcctgcaaca aaactatctc ctgtagcaat caaaccaaga tgccagtttt ggtccaattg
     3481 agataaactc tcttggattt gagcaacaaa ggttttgtct gattcgaaat aaagcggttg
     3541 ttgcgccatt tgtccataag catagccaaa agctgtgaca tccacgtcat gataggctaa
     3601 tttgtcagca atcacgacat ccccaacagc gataccttct gctactgccc cagctgaacc
     3661 cgtattaata agggcatcca cctggaaatg atcagccaaa atcgccacac tcatagcaga
     3721 catgacctta ccaattccac tttctacaag aacgacttca tgagaagcaa tggttcctgt
     3781 atgataggta ttccccaaaa caacttgctc ctgggcattg tctaaatgct ggaccagatg
     3841 agccagttct tctggcatag cagcaataat tcctattttc atttcaattc cttttctatt
     3901 acaaaagttt cattgctaaa acaagcaaaa tcaagagaaa gatgaccgcg aataagattt
     3961 tattcaactt agaattgaag acatttctct tggtattttc aatgcgacgg cttttatgaa
     4021 tagatggttc gacctgaatc ttcaaggttt cctggctaaa accatgatcc ttaggattgg
     4081 cataaccaaa acgggaagaa gaggttggta aaatcttagt ttcctcatta tcatccagca
     4141 aaggaggacc tgaaattttt tcgcctctat tagctctttc aatcatttca tccgttaata
     4201 aagatttacc catactgacc tcctctattt tttctgcaac tcccaatact gaacagccat
     4261 aattgtcttg gcatcacaga tatgacctga ttggattaat tctttcgctt cttctaagct
     4321 cacttcaagg acttccaagg tttcatcctc atcctgcgga cgcggatttt ccacttttgt
     4381 caaatcgctt gctaaatata gttttaactt ctcattacaa aagccaatag ctgaataaaa
     4441 atcgtacaag agttctaatt tccctgtata ggctgtttct tcctctaatt cacgaagggc
     4501 agctgccaca ggggctgtgt tttctcctac ctccaatttt ccggctggaa tttcgtaaga
     4561 gacagcctcg atagctttgc ggtactgctt gaccaagata agtttttgtt catccgttac
     4621 tgctaaaaca cagacagccc cattgtggaa aatcaaatcc cgttgggcag ttcccttgcc
     4681 ttctggtaat tcaacctgat cttggaccag tttaaatatt ggtccttgat agatttcttt
     4741 tcggctaagc gttttttctt caaactccat gataggctcc tactggttcc taggatgatg
     4801 aggaagacgt gttgcatatt cgtctttatt gatctgacga ccgcgaccaa tagcaatagc
     4861 atctgctggc acgtctttag taatagttga accagcacca acgagggaat tgtcaccaag
     4921 ttctactggt gcaataatgg ttgaatttga accaacaaag acattgtctc caatgactgt
     4981 cttgtatttg tttttgccgt catagttgac tgtaatagtt ccagcaccga aattaacgtt
     5041 gcttcccact tcacagtttc cgatataagt caaatgacca gccttggtat tctcaccgat
     5101 tgaagatcct ttcacctcaa caaagttacc aatatgaact tgggcaccca gacttgaatt
     5161 tggacgaatg tgagcataag gaccgactgt cacaccgtct gcaacactac tttcctcaat
     5221 catagaattg gtaatgaccg ctcctgctcc gatagtgctg tccactacat aagtaccgtt
     5281 tgtcaaaaca gtctcagcac caattttcgt ttgccctttc aaggtaacat tggcttcgat
     5341 ttgaacttcc ggagcaatct caacatcaat atcgatataa gttgcttctg gattgacaaa
     5401 gctaacacca ttgaccatgt gtttatgatt gatgcgacaa cgcataactg actcagctgt
     5461 cgcaagcgcc acacggtcat ttaccccaag actttcatca aaatctttca aagtataagc
     5521 gccaactttt tcaccagttt cacggaaaat accaatgacg tctgtaatat agtattcgcc
     5581 ttgagcgtta ttggtattga tatttttcaa agcctcaaac aaacgctcgt tgtcaaagac
     5641 gtatgttcca gtgttgattt ccttgatttg cttttcaaaa tctgtagcat ccttctgctc
     5701 aacaatacga agaacctcag cattgtcatt acgaacaatt cgtccatagc caaaaggatt
     5761 atccgtttca gcagtcaaga tagtggccac atttttatga ttgatatgga aatcaatcaa
     5821 gtttttcaag ctttcaccag tgattaaagg agtatctcct gcaatgacca aggtgtgtcc
     5881 tgacaaacct tctaagatag gctctgtcat cataactgca tgaccagttc ccaactgttc
     5941 agattgagtc acaaattctg tctgtccagc caagacctcc tcaaccaatt ctgccttgtg
     6001 tcctacaact gttactgtct tttcaggttg gatagctccc acactacgga aaacatgttc
     6061 caacatagaa atacccgcaa ccttgtgcaa aacttttggc aaatcagatt tcatgcgagt
     6121 ccctttaccc gctgctaaaa taatggcaaa atttgacata atcttctctt ttctgtagaa
     6181 attccctttt attataccat atttcaaatc attccgcact cttgaatgaa aaaatgctct
     6241 aaagtctctt ccttaaccca tttttttgat ttttagggta gaattataag atatgagaaa
     6301 acaaattcat ccacttattt tatttagttt tttggggatt atgatgttca ttttaatcat
     6361 caatcgccca cttaatgaca accaatcgtt taaaacaaaa tccaatatag cacagattga
     6421 agcacaggct ttgaaacact tagacaaacc gattattgac ctctctggct ggcagcgtcc
     6481 tgaggaaatc aactacgatg ccctctcaca aaatatttca ggtgctattg ttcgtgttca
     6541 cagtggtgct caaacgacaa aagaaaatga tgcttcattt atcaatggaa tagacaaggc
     6601 ctataagagt catatcactg aacttcaaaa gcggaatgtc ccagttgctg tctacgctta
     6661 tgtagctgga aaaagtgtcc aagaaatgga aaaggctgcc gaagttttct acaatgctgc
     6721 ctctccttac agccctagtt actattggct tgacgtggaa gacaaaacca tgtctaatat
     6781 gaacgaaggt gtcgaaaact ttcgagcaaa actagcatca ctaggtgcta aaaacatcgg
     6841 catctacgtt ggtgtctact tcatggaaga acacagtatt gatacaggca agtttacctc
     6901 tatttggatt ccgtcctacg gctcagactc aggatttttg gagagcagtc ctaaaactga
     6961 tttagattat gatattcacc aatacacatc taaaggaaaa attgccggct ttgaccacga
     7021 tttagatatc aacgttatct ctcccttaaa aaataaagaa gaaacctttc gaaaactttt
     7081 tttaaaacct taaaagcatt tgtttatcat ttgctttttc tttttgtgtc tgattgtgat
     7141 acaatatagt aaggattttt tgaaatagaa atagttggag gaaatatatg ctctcatggt
     7201 tagcacgcgt tattaaagga attgtgattg ctcttggatt tatcctaccg ggaatttccg
     7261 gaggggttct agcagcaatc ttaggaatct atgaacgaat gattggcttt ctggctcatc
     7321 cctttaaaga ccttaaagaa aatgttttgt actttattcc agttgccatc ggtatgcttc
     7381 tgggaatcgg cttattttcc tacccgattg aatacctgct tgaaaattat caggtctttg
     7441 tattatggag ctttgcggga gctattatcg gtacagttcc tagcctcctc aaagaatcaa
     7501 ctcgagaatc tgaccgagac aagattgatt tagcttggtt atggacaacc tttatcattt
     7561 ctggattagg actctattcc ttaaattttg tcgttggaac cttaagcgcc agctttctta
     7621 acttcgtcct agcaggcgca ctattggccc ttggcgtctt ggttcctggc ctcagcccat
     7681 cgaatttact tttgattttg ggactctatg ctcctatgtt gactggtttt aaaacttttg
     7741 atctcttggg aaccttcttt ccgattggaa ttggtgcagg tgcaactctc atcgtttttt
     7801 caaaattgat ggattatgcc ttaaacaact accactcacg cgtctatcat ttcatcatcg
     7861 gtatcgtcct atcaagtacc cttttgatct taattccaaa tacaggaaac gctgaaagta
     7921 tccaatacac aggactttca cttgtcggtt atgtcatcat cgccttcttc tttgcgctgg
     7981 gaatctggct tggtatttgg atgagtcaat tggaggataa atataaataa tggcaaaaaa
     8041 agttaaaatc aaaaaaacat tggtggaaca aatcctatct aaagcagcta tccctcatca
     8101 ggggattcaa atcaatgccc tagaaggaga gcttcctcaa ggttatgaac gagatcagat
     8161 tttcaaaacc ttggcgcttt tgggagacaa gaccggaccg attatcggaa ttgtccctat
     8221 cactcagcac ttgtctgaaa agaaactagc taaaatttct ggcaataaaa aagtgagcat
     8281 gattccacaa aaggacttag aaaaaacaac tggttacatt catggagcca ataatcctgt
     8341 cggaattcgt cagaaacaca attatcccat ttttatcgat aaaattgctc tagatttgga
     8401 tcgaatgatt gtctctgcag gcgaagtcgg acacagcatt atcgtcgcgc cacaagactt
     8461 ggctagcttt gtaaaggcag actttgtaga tattttggag gacatcaagt aatgaaactc
     8521 tactttgtcc gccacggtcg taccctctgg aaccaagaag gtcgttttca aggtgctagc
     8581 ggtgattctc ctcttcttcc tgaatccatt gaaaccctaa aacgacttgg ccagtatctc
     8641 aaggaaattc cttttgatca gatttattca agtgatttac ctcgagcggt caaatctgct
     8701 gagattatcc aaagtcaact ccataccccc tgttctttag aaatcgttcc taatctccgt
     8761 gaatggcaac ttgggaagtt agaaggtttg aaaattgcaa ccttggaagc tatttacccg
     8821 caacaaatcc aggcttttcg ttcaaatctt gctcaatttg acactcgaat gttcggagcc
     8881 gaatccctct atagtacaac tcagcggacc atccaattta tcaaatcatt aaaagatagt
     8941 ccagctgatc gtattctaat tgtcggacac ggcgccaatc ttactgccag tcttcgtact
     9001 ctcctaggct ataaagaacc acttcttcgt aaagatggcg gtctagcaaa tgccagcctg
     9061 accattatag aaacccatga ttttgaaaca ttcactctca atacttggaa tgatacttct
     9121 tatcaatcat aattatagcc tagccttctg aactagaacc ataggagata tagtcagttg
     9181 aaacaaaaat aagacaaaag aaccttgtaa aaaggtattg caacttgcca ataccttttt
     9241 gatatgaaca cgtgtcttct caacaggatt gtagagcaaa atgaaataag aactgaataa
     9301 tatgatttga gaatttaaat caatttataa gaatgtttta gaagcagtta tgtactattt
     9361 tagattcact tttctatact aagatgagta gggaggaaaa ggtaaaagtt tatgcccaaa
     9421 ttcttcacat aagaactcta gcttacccat tctatggaat cttgcattat ccattaaaac
     9481 ttccagactc atacccttct aaaatctatt caaaccacgt cagcttcaca ttatatatgt
     9541 tggtgacctc acaagtttta tctacaacct caaagctgtt ctttgagcag cctacagcta
     9601 gcttcctagt ttaatctttg cttttcactg agtatcaagt taaaaaaatg aggctggtca
     9661 aaaagtcttt aaaataaaaa acgcatatta tcaggtgtta aatgaactgc accccaaaag
     9721 ttagacagaa aaaatctaac ttttggggtg tttttattat gaaattaact tatgatgata
     9781 aagttcagat ctatgaactt agaaaacaag gatatagctt agagaagctt tcaaataaat
     9841 ttgagataaa caattctaat attaggtaca tgattaaatt gattgatcgt taatgttgga
     9901 acaggcattc aaagagaagc actacgagaa tacgattctc catagtgacc aaggctggca
     9961 atatcaacac gattcttatc atcggttcct agagagtaag ggaattcaag catctatgtc
    10021 acgcaaggga aacagccaag acaacggtat gatggaatct ttctttggca ttttaaaatc
    10081 cgaaatgttt tatggctatg agaaaacatt taaatcactt aatcaattgg aacaagccat
    10141 tatagacta
//
LOCUS       DAVLZG010000067        10095 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLZG010000067 DAVLZG010000000
VERSION     DAVLZG010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.067"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(35..271)
                     /locus_tag="VYO72_001779"
     CDS             complement(35..271)
                     /locus_tag="VYO72_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1708102.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(339..1259)
                     /locus_tag="VYO72_001780"
     CDS             complement(339..1259)
                     /locus_tag="VYO72_001780"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1708103.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDSDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1449..1852
                     /locus_tag="VYO72_001781"
                     /pseudo
     CDS             1449..1852
                     /locus_tag="VYO72_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2068..2649
                     /locus_tag="VYO72_001782"
     CDS             2068..2649
                     /locus_tag="VYO72_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1708104.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            2646..3923
                     /locus_tag="VYO72_001783"
     CDS             2646..3923
                     /locus_tag="VYO72_001783"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1708105.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3941..4603
                     /gene="deoC"
                     /locus_tag="VYO72_001784"
     CDS             3941..4603
                     /gene="deoC"
                     /locus_tag="VYO72_001784"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1708106.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4590..4979
                     /locus_tag="VYO72_001785"
     CDS             4590..4979
                     /locus_tag="VYO72_001785"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1708107.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5069..6121
                     /locus_tag="VYO72_001786"
     CDS             5069..6121
                     /locus_tag="VYO72_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1708108.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6265..7800
                     /locus_tag="VYO72_001787"
     CDS             6265..7800
                     /locus_tag="VYO72_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708109.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINMHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7793..8851
                     /locus_tag="VYO72_001788"
     CDS             7793..8851
                     /locus_tag="VYO72_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1708110.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLTELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8854..9810
                     /locus_tag="VYO72_001789"
     CDS             8854..9810
                     /locus_tag="VYO72_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1708111.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9895..>10095
                     /locus_tag="VYO72_001790"
     CDS             9895..>10095
                     /locus_tag="VYO72_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1708112.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMI"
BASE COUNT         2897 a         1781 c         2321 g         3096 t
ORIGIN      
        1 ttcttcaacc cactacagtt gacaaagagc cttcttattt agcaagttta gctgaaagac
       61 gagctttatc gcggcttgct ttgtttttgt gaatcaaacc tttagtttct gctttatcga
      121 tagctgagct agcagcacgg aaaagttctt cagatgggtt tgcttcgaaa gcttttatag
      181 cagtacgcat agctgatttt tgagctgagt tcttttcgtt ttgtttaacg ttcaattcag
      241 cgcgtttgat agctgattta atgtttgcca atgttcttac ctccatattt actaactata
      301 ccattatata tgaaaactta cgttttgaca agggaaaatt atttttttaa gtaaatttca
      361 tcgatttcat ggttcttgct tttatgaaga atcacttctg cacgatttct ggttggttca
      421 atataatttt gtagatttgt gagattgata ctggtccaga cctgatgggc aaaggcttcc
      481 acttccccaa tcggcatctg agtaaaacga taatagtagc tatcagagtc gttttgggct
      541 agactcagca ttttcaagaa acggtccaga taccaacttt caatatcatc cactccagca
      601 tctacataga tggaaaagtc aaagaagtca gtgatataga gacgatcgtt ttgtggattt
      661 tgaaagacat tgattccctc aacaattaca aaatcagcag ctttgacact ttgtttctct
      721 tcgggtacga tgtcgtaaac ttcatgagaa tagacaggaa tatctacatc ttgtccattt
      781 ttgatgcggt ccaagaagtt gagaagagct tccatatcat agctttcagg aaatccttta
      841 cgatttaaaa tcccctgctc aatcaaggtt tgattgggat agagaaaacc atcagttgta
      901 accaactcaa ccgtagcatc tgtaaacgta cgggacagta ggatttgaag taggcgactg
      961 gttgtggatt ttccaacggc aacactccca gaaaccccaa taataaaagg ttgagattta
     1021 ctttcacgtt ggaggaaaat tccttttgaa aaggctaaat cttccttagt tcgcttgtaa
     1081 atctgaatca gatgagccaa ggggagatag atatctgtaa cgtcttggag actgatttgg
     1141 tcattaaaac tcttgataga ttccaattct tcttctgtca aaggaggtgt tgtctttcga
     1201 tgtaaagatt gccaagtctg gcggctgatt ttttcaaaat gtaaaaattc gttggtcatt
     1261 tgttttcccc tagatatttt gtctatcata ccataaaaag ctaaaaaaat aaagcggttt
     1321 cttgaatgtg gtaagtcaat ggtatatagt ataagtgatc aatttattga tgaaatagga
     1381 gatagattct actgatttat aagcttataa agggggcttt ttagttcaca acttatagga
     1441 ggtgtactat gaaaatctta aaacgttaca tattggaact ctgttttatt ttaagttttg
     1501 ctttaccttt tataaaagga gccaatgcag ataatggtag atgctttgtg gaaacctatt
     1561 acggttttac ttttttgatg gaacatgcta ttgtaacagc tgtctttatc tgttcgttct
     1621 taattgcttt cttactaaaa aacgatgggc gaaatggatt gctgcgggta gttattgctt
     1681 tttagtccta cggattgcga cagagggtta tttcttccac atgtcactag aagatttgat
     1741 acgactttgg acaagtttgg aaatcctgac acaaacgtat cagttgggct tttatctaaa
     1801 cattttgtta ggaattttgt tgataataaa gtattttaag gttaagcaat agaaataata
     1861 atctgcctga ttatagatga taaacttttt gtttttatct ggactgtgat atttatagtt
     1921 ctaaatggtt tattatttat aagtgttgaa agagattgaa gaaaatggct tcgtgacttg
     1981 ctttcttcgg tctttttcgt tttattatca atttgtaaac gatttacaat ttgagtcaaa
     2041 ttatggtaaa atagtgtcat gagtaaaatg tactatgcag aaaatcctga cgctgctcac
     2101 gacattcatg agttgagagt ggacttgttg ggagaaaaaa tgactttttt gacagatgcg
     2161 ggtgttttta gcaagaaaat ggttgacttt ggaagtcaac tcttgctcaa gtgtctggat
     2221 gtcaaccaag gagagacagt cctagatgta ggctgtggct atggtccatt aggtttgtcc
     2281 ttggtcaagg tttacggagt tcaggcgacc atggttgata ttaacactcg tgccctggat
     2341 ttagctcaga gaaatgctga aaaaaataat gcaaaagcga cgatatttca atctaatatt
     2401 tatgcaagag ttcaagggcg atttgaccat gtcatttcca atcctcctat ccgtgcgggc
     2461 aagcaagtcg ttcatgaaat catcgagaaa agtaaagatt tcttggaaat tggtggagat
     2521 ttgaccatcg tcatccagaa aaaacaagga gctccaagtg ccaagtctaa gatggaagat
     2581 gtgtttggca attgtgaaat ccttaaaaaa gacaagggat actatatcct tagaagtgtg
     2641 aaagaatgag agcagttgat ttaatccaaa aaaaacgaga cggtcaagaa ctgacttcaa
     2701 gtgaaattga atggctgata gaaggctatg tatcaggaac tgttcctgat tatcagatgt
     2761 ctgcctttgc tatggctgtt tattttaaag gaatgacgac tcgagaaatc tctgatttaa
     2821 cgatgaatat ggttaagact gggcaagagt ttgacctgtc agccattgat ggtgtgaaag
     2881 ttgacaagca ttctactggt ggtgtcggcg ataaggtaac cttgatttta gctcctcttg
     2941 ttgctagctt cggtgtgcct gtagcaaaaa tgagtggtcg tggtcttggc catacaggcg
     3001 gaacaattga taaattggag tccattaagg gctatcaagt agaacgtagt caagaggatt
     3061 ttattcgtca ggttcaggat attggagtat ctgtcattgg gcaatcagac cagctggtca
     3121 aagcagataa gcttctctat gcccttcgtg atgtgaccgc aactgtcgac acgattcctt
     3181 tgattgcgag ttcggtgatg agcaagaaaa ttgcggcagg ggcggatgct attttgctag
     3241 acgtgactgt cggtgagggt gccttcatga agacggttga tgaggcgcgt gagttggctc
     3301 aaactatggt agatcttggt aaggttgttg gacggaagac agtagcagtg attacggata
     3361 tgagccagcc tttgggacga gcgattggaa atcgtctgga aatccttgaa gcattggaga
     3421 ttttgcaagg tcaaggacgt caggatatta cccactttat ttgtgaattg gctcaaatta
     3481 tgcttggttt ggcaaatgtt aacaaaactg ttgaagaagt tcgccaacat cttgaaaatg
     3541 gtcaagcact ggctaagttt gaggaaatgg tgcaagccca aggtggagac ttggaagacc
     3601 tctatcgtcc tgtaaatgta gctcatgtgg tggaaatccc tgctcaggaa acgggtgtca
     3661 tttcagctct tccagctatg gactttggtc tttatgccat gaggctgggt gctggtcgtg
     3721 cagttaagtc tgatgtcttg gactatgaaa caggaattgt ttttgaaaag aagattggag
     3781 actccgttca aaagggtgaa attgttgcaa aagtatacac aaatgaaaaa attccacctc
     3841 aactagttac agatttccaa aaatgtgtta aaataagtga tgaagtgaaa aaaatccgtg
     3901 aaattgtaga aatcatctcc taaatggagg gaaaaccgaa atgaaattaa ataaatatat
     3961 agatcatacg cttttaaaac aagatgcaaa gaaaaaacaa attgatagtt tgttgtctga
     4021 ggctagagag tatgactttg ccagtgtttg cgttaatccg acctgggttg aacatgctaa
     4081 aaaaggactt gaaggcacag atgttaaggt ttgcacagta gtaggtttcc ctttgggagc
     4141 aacaacttca gccgtgaaag catttgagac aaaagaagct atccaaaatg gtgcagatga
     4201 gattgatatg gtgatcaatg ttggagctct caaatcaggt aatttagcct tggttgagtc
     4261 agatattcgc gcagtagtgg aagcaagtgg tgataagtta gtgaaagtca ttattgaagc
     4321 ttgccttctg acagaccaag aaaaaattgt tgtttgccaa ttggcccaaa aagctggggc
     4381 tgactttgtt aaaacatcta ctggcttttc aactggtggt gctacgatag cagatgttag
     4441 attaatgcgt gaaacagttg gatctgatat gggagtcaag gctgctggtg gagctcgttc
     4501 ttatgcagat gctcttgcct ttgtcgaagc aggtgcgacc cgtatcggaa cgtcagctgg
     4561 ggtagctatt ttaaaaggag aattggcaga tggcgactac tgagttgatt gaactggcaa
     4621 ttgaaaccag caaacatgcc tatgtcccct attctcactt tcctatcgga gcagttttag
     4681 tagccaaaga cggaagtgtt tacacgggag tgaatatcga aaatgctagc tatcctttga
     4741 ccaattgcgg tgagagaaca gctgttttta aggctatatc tgaaggccaa agagaatttt
     4801 cagaattgat tgtctatggt caaactgaaa aaccgatctc gccatgtggt gcttgtcgcc
     4861 aagtaatggt cgaatttttt gaacaagatt taaaagtgac cttagtcgca aaagataaat
     4921 cgacggtcga gatgacggtc ggggaattac ttccatactc ttttacagac ttaaactagt
     4981 ctgagtcgct ctctgagtgg cacggtcctt gtggccaacc aatccatact tgcaacatcg
     5041 ttgcacatct tatttaggag gttcagtaat gaacaagaaa caatggctag gccttggtct
     5101 agttgcagtg gcagcagttg gacttgctgc atgtggtaac cgctcttctc gtaacgcagc
     5161 ttcatcttct gatgtgaaga caaaagcagc aatcgtcact gatactggtg gtgttgatga
     5221 caaatcattc aaccaatcag cttgggaagg tttgcaggct tggggtaaag aacacaatct
     5281 ttcaaaagat aacggtttca cttacttcca atcaacaagt gaagctgact acgctaacaa
     5341 cttgcaacaa gcggctggaa gttacaacct aatctttggt gttggttttg cccttcataa
     5401 tgcagttgaa gaagcagcta aagaacacac tgacttgaac tatgtcttga ttgatgatgt
     5461 gattaaagac caaaagaatg ttgcgagcgt aactttcgct gataatgagt caggttacct
     5521 tgcaggtgtg gctgcagcaa aaacaactaa gacaaaacaa gttggttttg taggtggtat
     5581 cgaatctgaa gttatctctc gttttgaagc aggattcaag gctggtgttg cgtcagtaga
     5641 cccttctatc aaagtccaag ttgactacgc tggttcattt ggtgatgcag ctaaaggtaa
     5701 aacaattgca gccgcacaat acgcagccgg tgcagatatt gtttaccaag tagctggtgg
     5761 tacaggtgca ggtgtctttg cagaggcaaa atctctcaac gaaagccgtc ctgaaaatga
     5821 aaaagtttgg gttatcggtg ttgaccgtga ccaagaagca gaaggtaaat acacttctaa
     5881 agatggcaaa gaatcaaact ttgttcttgt atctactttg aaacaagttg gtacaactgt
     5941 aaaagatatt tctaacaagg cagaaaaagg agaattccct ggcggtcaag tgatcgttta
     6001 ctcattgaag gataaagggg ttgacttggc agtaacaaac ctttcagaag aaggtaaaaa
     6061 agctgtcgaa gatgcaaaag ctaaaatcct tgatggaagc gtaaaagttc ctgaaaaata
     6121 atggatggaa gtcatttctt aggaagcggc caagggccgc ttttttaaga gttgagacaa
     6181 agtcattttg tctcagtaaa gcttgctact agacaaacta gcaagtttta ttgaaataaa
     6241 ataagactct gaaaggaaga gcacatggca cacgaaaatg tcattgagat gcgtgatatt
     6301 accaaggtgt ttggtggatt tgttgccaac gacaaaatca acatgcacct acgaaaaggt
     6361 gaaattcatg cacttttagg agaaaatggg gctggtaagt ccacgctaat gaacatgtta
     6421 gcaggccttc ttgaaccaac tagtggtgaa atcgcggtca acggtcaagt tgtcaatctc
     6481 gactccccat ctaaagcagc tagcttggga atcgggatgg ttcaccagca ctttatgttg
     6541 gttgaagcct tcacagtggc tgaaaatatc attttaggta gtgaattgac taaaaatggt
     6601 gtgctagata tcgctggagc tagcaaagaa atcaaggctc tttctgaacg ttatggctta
     6661 gctgttgacc cttctgccaa ggtagcagat atctcagttg gagcccaaca acgtgtagaa
     6721 attttaaaaa cactttatcg gggggctgat atccttatct ttgacgaacc aacggctgtt
     6781 ttgactccat cagaaattga tgagttgatg gctattatga aaaatcttgt caaagaggga
     6841 aaatcaatta tcttgattac ccacaaattg gatgaaattc gagcagtttc tgaccgtgtt
     6901 acagttatcc gtcgtgggaa atcaattgaa accgttgaaa ttgcaggggc taccaatgct
     6961 gatttggcgg aaatgatggt aggacgttct gtttccttta aaacagagaa gcaagcctct
     7021 aaaccaaaag aagtggtttt gtctatcaaa gatttggtgg tcaatgaaaa ccgtggtgtt
     7081 ccagctgtta aaaatctgtc cttggatgtt cgtgctggag agattgttgg tattgcgggg
     7141 attgatggaa atggtcagtc tgaactgatt caagccatta caggtcttcg taaggttgaa
     7201 tctggtagca ttgagctaaa aggagattca attgtaggct tgcacccacg tcagattaca
     7261 gaactaagtg ttgggcacgt tccagaagac cgtcaccgtg atggcttgat tttggaaatg
     7321 atgatatctg aaaatattgc ccttcaaacc tactataaag aaccacatag taaaaatgga
     7381 attttgaact attcaaatat tacttcttat gctaaaaagc tgatggaaga gtttgatgtt
     7441 cgcgctgcca gtgaattagt tcctgcagct gcactctcag gaggaaatca acaaaaagca
     7501 attattgctc gtgaaattga tcgagatcct gatctcctta tcgttagtca gccaactcgt
     7561 gggttggatg tcggtgccat tgagtatatc cacaaacgct tgattgaaga gcgtgataat
     7621 ggcaaggctg tccttgttgt cagctttgaa ttggatgaga ttttaaacgt ctcagaccgt
     7681 attgccgtta tccacgatgg taagattcaa ggtattgtat caccagaaac aaccaataaa
     7741 caagaacttg gtgtcttgat ggctggtgga aacttgggaa aggagaagag tgatgtctaa
     7801 aaaattacaa caaatttcgg ttcccttgat ttctgtattc ctaggaattt tactcggagc
     7861 cattgtcatg tggatcttcg gttatgatgc tatttggggc tacgaagaat tgttctatac
     7921 agcctttggc agtctgcgtg ggattggaga aatcttccgt gctatgggtc ctctggtctt
     7981 gattggtctt ggttttgccg ttgccagtcg agctggtttc tttaacgtcg gacttcctgg
     8041 tcaggctttg gcaggttgga ttctcagtgg ttggtttgcc ctgtcgcatc cagatatgcc
     8101 ccgtcccttg atgattctag caaccatcgt gattgccttg attgctggtg ggattgtcgg
     8161 agcgattcca ggtattctta gggcctatct agggacgtca gaggttattg taaccatcat
     8221 gatgaactac attgtcttgt atgtagggaa tgcctttatc catgctttcc ctaaagactt
     8281 catgcaaagt acagattcga ccattcgtgt tggggctaat gcaacctatc agacaccttg
     8341 gttgactgag ttgactggta actcacggat gaatattggt attttctttg ccatcattgc
     8401 cgttgcagtt atttggttca tgctcaagaa aacaactctt ggttttgaaa tccgtgcagt
     8461 tggtcttaat ccacatgctt cagaatatgc tggtatttct gccaagcgga ctattatcct
     8521 atctatgatt atttcaggtg ccttggcagg tcttggtgga gctgttgaag gtttgggaac
     8581 cttccagaac gtctatgttc aaggttcgtc attagctatc ggatttaacg gaatggcggt
     8641 tagtttgctt gcggccaact caccaattgg tatactcttt gcagccttcc tatttggcgt
     8701 tctccaagtt ggggctcctg gtatgaatgc ggcgcaggta ccatctgagc ttgtcagcat
     8761 tgtaacagcg tctattatct tctttgtcag tgttcattac cttatcgaac gctttgtcaa
     8821 accgaaaaaa caagttaaag gaggtaagta aagatgtcta ttataacctt gctccccctc
     8881 ttggtgtctt ctatgctgat ttactcagca cctctcatct ttacaagtat cggtggtgtt
     8941 ttctctgaac gtggtggtgt ggtaaacgtt ggccttgaag gaattatggt tatgggtgcc
     9001 ttttctggag ttgtctttaa ccttgaattt gcagaacaat ttggagcagc aactccatgg
     9061 ctatccttgc ttgtagcagg attggttggt agtgttttct ctatcatcca cgcagcagcg
     9121 acggttcatt tccgtgcaga ccatgttgtc agcggtacgg tattgaactt gatggcgcct
     9181 gccttggctg ttttcttagt taaagttctt tataacaaag gacaaaccga caacctaagt
     9241 caaacttttg gacgctttga tttcccagtc ttggcaaata tcccagtgat tggtgatatc
     9301 ttcttcaagt caactagtct acttggttat ctggcgattg ccttctcatt ccttgcttgg
     9361 tttattctct ttaagactca atttggtctt cgtctccgct ctgtcggtga acatcctcaa
     9421 gcagcggata ccttgggaat caacgtctac aagatgagat atttaggggt tattatttca
     9481 ggttttctag gtggaattgg cggagcgatt tatgcgcaat caatctcagt taacttctca
     9541 gtgacaacta ttgttggacc tggatttatc gcccttgctg cgatgatctt tgggaaatgg
     9601 aatccaatcg gtgctatgct ttctagtctc ttctttggac tttcacaaag tttggctgtt
     9661 atcggttctc aattgccgtt cctacaagga gtgccagcgg tttatcttca aattgcacct
     9721 tatgttttga caattcttgt cttagcagcc ttctttggaa aagcagtcgc accaaaagca
     9781 gatggtatca actacatcaa atcaaaataa gcatacaaaa aaacgtcagt ccaatgactg
     9841 aactacaccc caaaagttag acagaaaaaa tctaactttt ggggtgtttt tattatgaaa
     9901 ttaacttatg atgataaagt tcagatctat gaacttagaa agcaaggata tagcttagag
     9961 aagctttcaa ataaatttgg gataaataat tctaatctta ggtacatgat taaattgatt
    10021 gatcgttacg gaatagagtt cgtcaaaaaa gggaaaaatc gttactattc tcctgattta
    10081 aaacaagaaa tgatt
//
LOCUS       DAVLZG010000068         9291 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLZG010000068 DAVLZG010000000
VERSION     DAVLZG010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.068"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            5..1246
                     /locus_tag="VYO72_001791"
     CDS             5..1246
                     /locus_tag="VYO72_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1708113.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(1477..2889)
                     /gene="sufB"
                     /locus_tag="VYO72_001792"
     CDS             complement(1477..2889)
                     /gene="sufB"
                     /locus_tag="VYO72_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1708114.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVICELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(2943..3383)
                     /locus_tag="VYO72_001793"
     CDS             complement(2943..3383)
                     /locus_tag="VYO72_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1708115.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(3370..4596)
                     /locus_tag="VYO72_001794"
     CDS             complement(3370..4596)
                     /locus_tag="VYO72_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1708116.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPAIARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(4607..5869)
                     /gene="sufD"
                     /locus_tag="VYO72_001795"
     CDS             complement(4607..5869)
                     /gene="sufD"
                     /locus_tag="VYO72_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1708117.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(5897..6667)
                     /gene="sufC"
                     /locus_tag="VYO72_001796"
     CDS             complement(5897..6667)
                     /gene="sufC"
                     /locus_tag="VYO72_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1708118.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(6817..7011)
                     /locus_tag="VYO72_001797"
     CDS             complement(6817..7011)
                     /locus_tag="VYO72_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1708119.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(7039..8694)
                     /gene="dnaX"
                     /locus_tag="VYO72_001798"
     CDS             complement(7039..8694)
                     /gene="dnaX"
                     /locus_tag="VYO72_001798"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1708120.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(8694..9191)
                     /locus_tag="VYO72_001799"
     CDS             complement(8694..9191)
                     /locus_tag="VYO72_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1708121.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
BASE COUNT         2710 a         2070 c         1754 g         2757 t
ORIGIN      
        1 tactatgaaa aaaatatttt taactttgtt aactgtctct cttttagggg gtgcttctac
       61 tgctgttgct caagatttta ccattgccgc taaacatgcg attgctgttg aggcaaatac
      121 tggtaaaatt ctctatgaga aggatgcaac gcaacctgtc gaaattgctt ccataacaaa
      181 attgattact gtttatctgg tctatgaagc tttggaaaac ggaagtatta ccctctccac
      241 tcctgtagat atttctgatt atccttatca attgacgaca aattctgaag ccagtaatat
      301 tcctatggag gcccgtaatt atactgtcga agagttgctt gaagcaactc tggtatctag
      361 tgccaacagc gccgctattg ccctagctga gaaaattgct ggctcagaaa aagatttcgt
      421 cgatatgatg cgggcaaaac tcttggaatg gggaattcag gatgccactg ttgtcaatac
      481 gacaggtctt aacaatgaaa ctctagggga taacatttac ccaggttcta aaaaagatga
      541 ggaaaataag cttagtgctt atgatgtcgc tatcgttgct cgcaacctca tcaaaaaata
      601 cccacaagtc ttagaaatca ccaaaaaacc ttcttctact tttgctggga tgacaatcac
      661 ttcaaccaac tacatgttag aaggtatgcc tgcttaccgt ggtggttttg atgggctaaa
      721 aacaggaaca acagataagg ctggagagtc ttttgttggt actactgtcg aaaaaggcat
      781 gagagtcatc acagttgttt taaatgcaga tcatcaagac aataatcctt acgctcgatt
      841 tacagctaca tcttccctaa tggattatat ttcttctaca tttacacttc gcaaaatcgt
      901 tcaacaaggc gatgcctatc aagatagcaa agcccctgta caagatggaa aagaagatac
      961 agtaactgca gtggctccag aggatatcta tctaatcgaa cgtgttggga atcaatcttc
     1021 ccaatctgtt caattcacac ctgattccaa agcaatccca gcaccacttg aagctggaac
     1081 agtggttggc catttgactt atgaagacaa ggacttgatt ggtcaaggtt acatcaccac
     1141 agagcgccct agtttcgaaa tggtagcaga caagaaaatt gaaaaagcct tcttcttaaa
     1201 agtttggtgg aatcagtttg tccgctttgt taacgagaaa ttataaaaaa tcgcgatttt
     1261 aaaccgcgat tttttgatac aagttcatct tcaaaatcct tgattttgag taaatctaat
     1321 actcaaaatc aaagaacaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga
     1381 ggttgtagat gaaactgacg aagtcagtaa ccatacatac ggtaaggcga tgctgacgtg
     1441 gtttgaagag attttcgaag agcataaaat caaattttat ccaactgatc cctccatttc
     1501 atagctaatc aagcggttca gctcaactgc gtattccatt ggaagttctt ttgtaaaggg
     1561 ttctacaaat cccatgacaa tcatttcagt tgcctcagat tctgacaatc cacggctcat
     1621 gagataatac aattgctctt ctgaaatctt agatactttg gcttcgtgtt ccaaagccac
     1681 ttgcgagttg tgaatttcat taaatggaat agtatctgat gctgacaagt catccatgat
     1741 aatggtatca cattcaatgt gggaaacaga tttcttagag ttcttgttaa aggtgacttg
     1801 tccacggtag tcaacctttc ctccaccttt agcgatggat ttagacacaa tagacgagct
     1861 ggtatgtgga gcattgtgaa tcatcttagc acccgtgtct tggtgttgcc ctgcattagc
     1921 aaaggcgata gagagcatgg taccacgcgc tccttctcca tcaaggtaaa cagatggata
     1981 tttcatagtc gttttggcac ccaagtttcc atcaatccac tcaacagtgg catccttttg
     2041 agccttagca cgctttgtta ccaagttata gacgttatca gaccagtttt ggatagttgt
     2101 ataacgcata taagctccgt ccaaagcaaa aatttctaca atggcagcgt gtaagctatt
     2161 gcttgaatat gttggtgctg tacatccttc tacgtagtgg acgcttgctc cctcatcaac
     2221 gataatcaag gtacgttcga actgacctat attttcgtta ttgatacgga aataagtttg
     2281 aagtggaata tctaccttga caccttttgg cacgtagata aaagttccac ccgaccatac
     2341 tgctgagttg agggctgcca acttgttatc tgtcggcggt accaacttcg caaagtattg
     2401 tttaaataag tctgggtatt ccttgagtgc ggaatctgta tctgtaaaga taatacctaa
     2461 tttttggaac tcttccttca tgttgtggta aaccacttct gactcgtact gggcagaagc
     2521 ccctgctaaa taagcacgtt cagcttctgg aatcccgata cgttcaaagg tttctttaat
     2581 cttttcaggt acatcatccc aagaacgggc tggtttgtca gatggttttt ggtagtagat
     2641 taagtcatca aagtcaatct ctgacaagtc tgctccccaa gtttgcatgg gcattttttt
     2701 gaaggtttca taagacttca aacggaactc caacatccac tcaggctcac ccttagcagc
     2761 agataattca caaataacac cttcgttgag tccttttcct gtcgataaga caggctctac
     2821 atcgtcatgg aaaccaaatt tatattcacc aaggtcaatt ggttttggtt ctactctttc
     2881 ttcagccata atatcctttc tttcttcatt tctaataatt cataagacaa aagaaacttg
     2941 tcttactgtt tttcttgatt ttcaattgtt ttcttaaggg cattccaagc tagggttgca
     3001 cacttgattc tttgagggaa tttggcaaca cctgacaaga atgccgcgtc tccaagttgg
     3061 tcttgacgct catctttttg cccttgaacc atttcagaaa aaatagtcgc cagttctaaa
     3121 atttcttgtt tggtttttcc taaaacggca tctgtcatca tactagcaga agcagttgaa
     3181 atcgtgcatc ctgaatttag aaaagcaata tcttccaaac ggtcctctgc atcaaacttg
     3241 acagagaggt tgatgacatc cccacaagtc ggattgttga gactgatttg ctcagcgtct
     3301 tctaacttcc cttggtgatg tggatttttc gaatggtctg ctaccactgc catataaagg
     3361 ctatctagtt tagaaagtgc cattgaaaaa ctcctttgtc ttttgtaggg catcgactag
     3421 tttgtcgcaa tctgccttgg tattgtagat ataaaaactt gcacgagcta ttgctgggac
     3481 ttccaaatac tgaagcaagg gttgcgcaca atggtgacca gcacgaacag ccactccttc
     3541 ataatccaga gccgtcgcaa gatcgtgagg atggagatca cctaggttaa aggcaataac
     3601 acccgaacgt tgagccaaat cctgagaacc gtaaatggtc aatccctcaa ttgcctgcag
     3661 ttttggatag acgtacgcaa tcaattcctg ttcatgagct tcaatggcat ccataccaat
     3721 cttttccaga taatcaactg cagtcgcaag tccaatagct cctgccatat ttggcgttcc
     3781 agcctcaaat ttccaaggca attccttcca actagcagat tgctcgtaga caaaatcaat
     3841 catctcgccg ccaaattcta ctggagacat ttgctcaaga tacttttctt tgccgtaaag
     3901 gacaccgata ccagtcggac cagccatctt gtgacccgaa aaggcgaaaa agtccagatc
     3961 caagtcctgg acatcaatct tcatatgagg tgtagattga gcaccatcca ctaccatgat
     4021 tgccccaact tggtgggcta attgagtgat ttccttgatc ggattgacca caccaagaac
     4081 attggaggca tgagctaggg aaacaaattt aaccttatca gtcaatttag ctcgcaaatc
     4141 ctccatatcc aaggcaccgt ctttaagata gacatagaca agctctgctc cagtctttcg
     4201 acaagcttcc tgccatggaa tgatattaga atggtgttcc attactgaaa tcaagacctg
     4261 gtctccctca gtgagaattt cctcagcaaa gcgtgccacc cagttaaggc tggttgtcgt
     4321 tcctctggta aagagaactt cctttgtaga gcctgcatta ataaacttac gaatggtttc
     4381 acgagcagct tcataagaag ctgtcgctcg ttccgctaag gtatggacac cacggtgaac
     4441 attggcattg tcctgctcat agtagctgtt aatagctttc agaactacta gtggtttttg
     4501 tgtcgtcgca gcattgtcca gatagaccag aggttcatca ttgacaatct gatctaaaat
     4561 tggaaaatcc ttgcgaatcg cttctacatc taacataggc tgccccttag cgttttgaca
     4621 atttctcttc gatagttgca atcatttcat cacgaacttc cttgactgga atctccacga
     4681 taacagatcc aaggaaacca cgaacaacca aacgctctgc agttgcctta tccaatccac
     4741 gactcatgag gtaatacatg tcttctggat caacttgtcc gatagacgct gcgtgtcctg
     4801 cagtgacatc attttcatca atcaaaagaa ttgggttagc atctgaacgc gcttggtctg
     4861 aaagcatgag aacacggctc tcttgttggg catctgctcc cttagcaccc ttgatgatgt
     4921 ggccgatacc attgaaagtc aaagttgctt tttcaaggat aaccccatgt tgtaggatat
     4981 ttccgataga gttgcagcca tagttagtta cacgagtatc aatcccttgt acctgacgac
     5041 cacttgaaag agctacaacc ttgaggtcag catggctacc attaccaatc aagtcactat
     5101 caaaatcagc aacgacattt ccttcgttca tgacaccgat agcccagtca atacttgcat
     5161 cgttgcctaa tttaccacga cggctaatgt aggcagtgac gttttcacct agtcggtcga
     5221 tagcagcaaa cttgacttgc gcacctgaac gtgcaatcac ttctactgtg atattagcag
     5281 ttgctttggc acttccttca ccgcgtgact ctaaacgctc cagataatta atcttagaat
     5341 ttttaccagc gataatcata atatgcttgt taaacggcac attgctatcg ctatcttggt
     5401 agaaaattcc ttcaattggc tctgtgattt ctacgttatc tggaatatag agtacagcac
     5461 cactgttaaa gtaagctgtg tggtaagccg ccaacttgtc atcatcatac ttaacagatg
     5521 acatgaagaa ttcttcgatc agctctggaa tttcttctaa agctgagtga aagtctgtga
     5581 agacaacacc ctgttcagct aactcaactg gagtttgttc gaaaacagtt tgagttccta
     5641 cttgcaccaa cttcaagtga tgatctaaag ctgtgaaatc tggaacattt gctgatggct
     5701 cattttctgt aatcgttcca tcacccagat tccaacggtg gaatttgaca cgctcaataa
     5761 ctggtaattc caaagtctca atcttgtcaa aagctttttg acggagatca gccaaccagc
     5821 ttggttcagc gtgcatttct gaaaaaagtt taatattttc tctagtcatt tacttctcct
     5881 aaaagatacg agggaattac aattcttcct tgtagtcgta gccaagttct tcagctaatt
     5941 ttgcgtatcc ttcacgttcc aaacgcgcag ccaattctgg accaccagaa aggacaacac
     6001 gaccttccat catcacgtgt accacatcag gtgtgatata gttcaaaaga cgttggtagt
     6061 gagtgatgat catagcacca aaaccttcac cacgcatggc attgacacct ttagacacaa
     6121 ctttaagagc gtcaatatca agacctgagt caatctcgtc caaaagagca aatgttggct
     6181 ccaacatcaa aagttgaaga atttcattgc gttttttctc accaccagag aagccttcgt
     6241 tgaggtaacg ctctgccatt tcttctttca tgttaagcaa ttccattttt tcatctagct
     6301 tagtaataaa ctcacgaact gaaatcttct catcatcttc tttacccgca ttcatagcgg
     6361 cacgaagaaa ttcagcattg gtaattccag ggatttctga tgggtattgc atagcaagga
     6421 aaagtcccat acgcgcacgc tcatccactt ccaactcaag gatgtttacg ccatcaaaca
     6481 aaacttcacc tttagttact tcatagtttg gatttcccat gatagcggca gaaagagtcg
     6541 atttacctgt accatttggt cccatgatag cggcaatttc tcctgttttc agggtcaggt
     6601 taaccccttt taaaatttct tttccttcaa tctcaacgtg aagatctttg atctctatta
     6661 ctgacatgat agttcctttc tttttcaaaa cttttacagt acttactaga aaaacgtctg
     6721 atttccccag aaatagagca aaaattctat aaatatactt ttctagtata acaaaaaaaa
     6781 gcctaaaagg ctttgatttt gtctggaagc tgagggctag tctttcctat taaaatgctg
     6841 atcgatgaca tcaacgattt tacccatcac ataactgact cggaaatttc taaagagtaa
     6901 aattgcccaa aaggctgcca taatatagcg gccagtcatc caggcttcat tgaaaaaata
     6961 ggtctcagca gctgtaaata gcgccataat aataaattgt tgtttattca taaacttatt
     7021 gtatcatgaa atctttcttt agtcttcctc taccttcact ttatcagcca aaaattcaaa
     7081 tccttctgga atcaggcttt cttctacttc tttttcagtt tgagaagatt tggctttggc
     7141 tgaaaaggct gcgcgaactt ctttccattc ctccatggaa atagctaaaa tctcaggtga
     7201 aaaacctgcc gcctgactga ggatattacc aaacatggta ttgagattgt ctcgtttcat
     7261 agtttgacca gcattgaagt tagactcaaa agcaagaata gcatggtgtt cattggcagc
     7321 aaccggttga gaaccagcta gcagagcctt gtccggccca cctagacttt caattacctc
     7381 tccccaggca ttctgcaaac gaattaaatt ttgacgtgct aaatcaggat tttcgacggc
     7441 ctcttgtaag atagattgca ctttattgcg atcgacacga tagactgttt tgcccgtagc
     7501 tggtcgacta ggagctggtg caacttgttt aggaaccgca cctgcattag aaagctcttg
     7561 tttgagacgg gcaacttcct gtctcagcgt agcaatttca ttttcaaccg ctcctgatag
     7621 agctggttcg ggcttgattt ccgccaaacg gacggtcatc atttcagcat aaatcttggg
     7681 ctgcaaacta gacttaatat ctgctaaatt cactgttgct aagcgaatca tttcaaacag
     7741 atttttttga ggaagtgcca aattttctac aaagactgaa ctatgatgag tattttctcc
     7801 ccctgtttga acaattaaca agtctcttaa atagtgcaaa agatcggtca caaaacgagt
     7861 catgctctta ccattgtcaa aaagaagatt caagcaagac aaagctttgg gaacatcctg
     7921 ttgagacaag gccgccacat aatcatccaa ggctgatagg ctaatggtgc cagtaatttc
     7981 ttcagagata gcagtcgtca gctcatttcc ctgtgtcaaa ctcagggctt gatccaaaat
     8041 agacaaggcg tcccgcattc caccttccgc ccgtctggca atgatttcca cagcctctgg
     8101 ttcagaactg atattttctt tttctaagat atagtgaata tgttccttaa tatcctgtgt
     8161 cttaattgat ttaaactcaa aacgttgcac acgggataga atagtagcag gaatcttgtg
     8221 caattcagta gtggccaaaa taaagactac attctgtgtt ggttcttcca acgtctttag
     8281 gagggcatta aaagcccctg tagacagcat gtgaacctca tctatgatat aaaccttata
     8341 acgagcaagg ctaggcgcat aggtagattt atcacgaatt tcgcgaattt catctacccc
     8401 attattagaa gctgcatcca tttcaatgac atcttctaaa ctaccgtccg tcactgcttg
     8461 acaaatatag cagttattgc aaggttcgcc acccacttga ttgggacagt tcatagcctt
     8521 ggcaaagatt ttagcaacac tggtttttcc cgttccacga ggaccagaaa aaagataagc
     8581 gtgacttatt ttctcttgct ccaccgcttg tttaagagtc ttagccacaa cttcttgacc
     8641 aactaactgg gagaagtttt gacttctata ttttcgataa agtgcttgat acattaagat
     8701 ttttcctcaa acatcgtaaa gtcccatgtt gtcttttcaa gcaaaatagc gacaaattgt
     8761 tccaaataat ctcgatccat agcatcgtaa tcctcaatct ctgaagaatc cagatccaga
     8821 actccaagta actgaccatt cttcatcatc ggcaccacaa tttcactttt agctagacta
     8881 tcacaagaaa tatagttgag ataggtcgtc acatctccaa caataacagt ttcctgaaag
     8941 tgagctgcct caccacaaac ccccttgcct agtgcaatac ggatgcagga aacacctcct
     9001 tggaaggggc ctaaaaccaa ttcctttcca tcgaacaaat aaaagcctgc aaatacggta
     9061 ttaggaaaac gtgattttat gagagcactg gcgttggaaa gattagccaa aacattggtt
     9121 tcgccttcca ataggaagga caattcttca tttaacattt gataacgtga ttgtttttct
     9181 gattttaaca tagaactatt atatcaaaaa aggagcagag acaaaagaaa aatcccttgt
     9241 ttagtaaaca aaggattttg gactctataa tatttgtagt gggtaaatcc a
//
LOCUS       DAVLZG010000069         9179 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLZG010000069 DAVLZG010000000
VERSION     DAVLZG010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.069"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(120..1316)
                     /gene="tuf"
                     /locus_tag="VYO72_001800"
     CDS             complement(120..1316)
                     /gene="tuf"
                     /locus_tag="VYO72_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1708122.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2238..3107)
                     /locus_tag="VYO72_001801"
     CDS             complement(2238..3107)
                     /locus_tag="VYO72_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1708123.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3331..3951)
                     /locus_tag="VYO72_001802"
     CDS             complement(3331..3951)
                     /locus_tag="VYO72_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1708124.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKAPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEPTPEPGTPKTETPVNLDPEV
                     PTYETGKREGLSNTGTEANATLASAGIMTLLASLVLGFFKKKEDEK"
     gene            complement(3909..5015)
                     /locus_tag="VYO72_001803"
     CDS             complement(3909..5015)
                     /locus_tag="VYO72_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1708125.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5126..5380)
                     /locus_tag="VYO72_001804"
     CDS             complement(5126..5380)
                     /locus_tag="VYO72_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708126.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5738..6271)
                     /locus_tag="VYO72_001805"
     CDS             complement(5738..6271)
                     /locus_tag="VYO72_001805"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1708127.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6258..6584)
                     /locus_tag="VYO72_001806"
     CDS             complement(6258..6584)
                     /locus_tag="VYO72_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1708128.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            6818..8536
                     /locus_tag="VYO72_001807"
     CDS             6818..8536
                     /locus_tag="VYO72_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1708129.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKEIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8647..8994
                     /locus_tag="VYO72_001808"
     CDS             8647..8994
                     /locus_tag="VYO72_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1708130.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
BASE COUNT         2630 a         1886 c         1732 g         2931 t
ORIGIN      
        1 tatagtttgc tctttgattt tcattgagta ttagttcaat atctaaaaaa agaaccttgc
       61 caagcaagat tcttttagtg tctgacttaa ataattgttc ttctgggaac taaatcgaat
      121 taagcttcga tttctgtaac catacctgaa ccaacagtac gtccaccctc acggatagag
      181 aatgtagtac cttgttctac ggcgattggg tgaatcaact caacgtcgat tgtcacgtta
      241 tcaccaggca ttaccatttc agtacctgct ggaagttcga ttgaacctgt aacgtcagta
      301 gtacggaagt agaattgtgg acggtagttg ttgaagaatg gagtgtgacg tccaccttct
      361 tctttagtaa ggatgtagac ttcacctttg aatttagtgt gtgggttgat tgaacctggt
      421 ttagcgataa cttgtccacg ttcgatttca tcacgttgaa caccacgaag aaggacacct
      481 acgttatctc cagcaagacc ttcgtcaagt tgtttacgga acatttcaac accagtaaca
      541 actgcttttt gagtttcttc tttgatacca acgatttcga tttcgtcgtt gactttaacg
      601 ataccacggt cgatacgtcc tgaagcaact gtaccacgtc cagtgattga gaatacgtcc
      661 tcgactggaa gaagcaatgg tttgtcagtg tcacgttctg gttctgggat atactcatca
      721 actgtgttca tcaattccat aacgatgtct tcgtatttag agtcaccttc aagagcttta
      781 agtgctgaac cttggataac tggaagatcg tcacctggga agtcgtattc tgacaatagg
      841 tcacggattt ccatttcaac caattcaagc aattcttcgt cgtcaaccaa gtcaactttg
      901 ttcatgaaga cgataaggtg tttaacacca acctgacgtg aaagaaggat gtgctcacga
      961 gtttgtggca ttggtccgtc agttgaagct actacaagga tagctccgtc catttgagca
     1021 gcaccagtga tcatgttttt aacgtagtcc gcgtgtcctg gagcgtcgat gtgagcgtag
     1081 tgacgttttt cagtttcgta ctcaacgtgc gcagtgttga tagtgatacc gcgttcgcgt
     1141 tcttctggag cagcatcgat agacgcatag tctttaggtt ggttaactga tgaaggcaag
     1201 cgacgtgcca aaacagttgt gatagctgca gttagggtag ttttaccgtg gtcaacgtgt
     1261 ccgatagtac caatgttaac gtgtggttta ctacgatcgt atttttcttt tgccatttga
     1321 gtaaaagcct ccaataaaat atattttata gatagacagt aggcaataca gtctaacttt
     1381 ccttactatt ttatcaaatt tcagctaaat tgcaagtgtt ttacaacgtt tttgtgaatt
     1441 attcttggta aaaatttaac taattaatag aaagtactaa atagacttat ccttcaagga
     1501 gttttcagca ttatccatcc actcacttgc tgaaaatgta aacagtctct ggtttatata
     1561 gtaaaatgaa acaagaatag ggcaaatcga tcaggacagt caaatcgatt tctaacaatg
     1621 ttttagaagt agatgtgtac tattctagtt tcaatctact atacaacctc aaaactgtgt
     1681 tttgaacaac ctgcggctag cttcttagtt tgccctttga ttttcattga gtataaaatt
     1741 gcagataaaa cgataacaat cataggactc agcagagtca atgtaggtcg aagaatagcc
     1801 cccctaatcg cttattttat agcaaaatga aatagaaact gaacattttg ttgaggaagg
     1861 taaatcaatt cctcacaatg tttgagaaag aaggggggac tattccaact tcaacccact
     1921 ataaagcaga cttacaagat agggaaccca tctccgataa tattccgata atatatagta
     1981 gaatgaaaac tgcacaattt gattggagaa ttcaaaccaa tttctaacaa tgttttagaa
     2041 acaagggtct attatttcaa ctgcaaccta ctatagccca ttgaagctgg aatagcccac
     2101 tgagacttct aaaccactgc tggagaggag tttgtttaga gtttctttca tttccctaaa
     2161 aaatcaaaaa gagagaacca gtctgatcct ctcttactta tagatggtgc tcactcaaat
     2221 gttaaaggag ctatttctta gagataaagg aatttgaata cagctactgc cgcaattgct
     2281 gctgcgatag gtgctactac tggtacccaa gaataccacc attttgaatc gcctttatgc
     2341 tcaccaagaa ctgattttgg aaggaaagca tgaaggagac gtggtcccaa gtcacgggct
     2401 gggttcaagg caggtcctgt aggtcctcca agtgatgtta ccaaagccat aacgaggaat
     2461 ccaagtgcca agtgagccac agaaagtcct gaagcagtgt gtggagccac ctgtgcttta
     2521 atagccaagt cagaaaaatc aactgtttgt cctgcttcta ttgccttttg tttcatgaat
     2581 tgaagcactt cagcaccaaa gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca
     2641 aatgaaccaa caaactcatt aatcaaacca ttgacagttg ctgcatagcg actttctttt
     2701 gtaccatggt caatacttga aatagttgag aaagttccca agatgttatt tgggttttca
     2761 gttttcaagt agaatggacg gtatgttgcc acaactaagg cttggccaaa gatagccccc
     2821 aagacttgcg cgataatgta aggtaccact tgtgcccaag ggaaaagacc gctaactgca
     2881 agccctagag tgaaagcagg gttgatgtga ttcccagata cgttaccaaa catcaaggct
     2941 gggatcataa cccccatacc ataaccaaca gcgatgacga tccagccact ttggtgacct
     3001 ttcgtacctt taagttcaac gttggcaact gcaccattcc caagaatgat caaaatggca
     3061 gttcccaaaa attcagtggc atacttcagt gcccatgtga aatccatttg ctagattctc
     3121 cttaaaattt tttagatatt ccttatttta tcaattttta ccctatttag caactgattt
     3181 ctggaaatat ttttaaaaaa ataggattca tagtttccca gttcaacgga cttgtaagcg
     3241 tttttattct tcacgaaaga cctcgttctc aaaaccagga aaaaagccca catctgtgag
     3301 cttttcctgg ttcctagatt ctaaaatcta ttatttttca tcttcttttt tcttgaagaa
     3361 tcctaatact agactagcta acaaggtcat gataccagca ctagccaagg tagcattagc
     3421 ttctgtacct gtgtttgaca atccctctct cttacctgtc tcataagtcg gaacttctgg
     3481 gtctagattc actggagttt cagtttttgg agtacctggt tctggagttg gctctggtat
     3541 tggagtctct tgatttggta gttctgggtt tggtgtcgga acacttggat gctctggatt
     3601 tggttgtggg attggttttt ctggagttgg tttatctggt gttgataaac ggtcatacct
     3661 taccgttatt tctttatcac tagagtctga cgtaacttct tgtgattcaa ctgttggaat
     3721 atctggagct ttgtacttgt caatcttacc agatacaacc tcgtcccagt ttcctgttgt
     3781 ccattcaccg taggttacaa ctcccgtgac cttgttctca gtttttgtac ggcttaaggt
     3841 tacaggttga acaacatctt cttttacatt ttggttcgta actttatcaa cgtaatgaat
     3901 gatacgcgtt atagtcttcg tctcagtaga ggttgctgtt ttgggaacca ctgtttcctc
     3961 aacattctca cggtagtaat agtcaactgt tgcaccgtct tctggtacgc atttgcagga
     4021 gttgctacca aggtgtatgt tgttttcctt gtgataactc ggtcttcttt gtcctcagtt
     4081 gttgttttcc cttcaatagt ttttgattct gtggtatact cagaacctat cgctaaatca
     4141 gcttttataa cagactctgc caacttctct tggctacctt ctttatagta attggctgtt
     4201 actgtagcag tggttggcgc ttcgctttct ctataaacta aggtcactgt tctaccttcg
     4261 cttacaatat tcccagttaa acttgcagaa tttgtatctg cttctttaaa agtataatat
     4321 tttccgtcag tagtagtcat gctactgagt tttttatctg tgacattgta gctggtacca
     4381 atcagttgtt ttttattggt aatgtaggtt ccgtcacttt ctttttctcc aattccagta
     4441 tcatttttca atgatagcaa acgcccttgt tcatcaacat agcgaacttt cacattttct
     4501 gagattagtt ctgccaattc tgaggttttt ttctttttct tgatttcttc ggttattttc
     4561 cctttctctt cttcgggaat atttagtttt ggaatgattt tttcaacaac ggttcgtgat
     4621 ggttccacag tatcttggat gactgaaaag tcagctagaa ttgggagatt atactgaaca
     4681 cggtgacttt gagtgtttac tcctactctt tcattattct ctgaaaatac ttgtacggta
     4741 taagaaacaa catcttttcc taatagaaca tccccagtag agaaatagcc gccttttcct
     4801 agtttgctat ctccagagtc cacttctttc ctaatcttat cagatagttt tttaccagtc
     4861 agtacattcg ttcgcacaat ccctttgtct acccctacaa agtgggagaa ctttttgaac
     4921 tcttcagaac cagatctagc ccaaccatta ttaagggcat ttgcttttgt atttgtattc
     4981 tctctcaaag gtttggcgat tagaattata ttcatcggca cttagagttg ctgctatatc
     5041 tgactcttga ataccaactt ccttactacc atttctagcg gcagtatatg tgtatttatc
     5101 tgtttctact tctagctgat tatccttaac atgataggta attttctcct ggtataagag
     5161 tcttcagtag tttatatgct ctgtcatcat ctttagcttt agaagcagct gagtttagcc
     5221 aagttggggt attaggagta tctttatcag cctgtttcaa gacattattc aagtcatttg
     5281 ctaacctatt ggttgtcctc actgtgaaag ttttcttcca gtctgaatca cttttattag
     5341 acttagatat gctcatgaaa tcctggtcaa cattcaacac aatatcgcct tgttttttag
     5401 catcttccgt tgcttctgct tcaaattgat catggagttt ttgttgctct ggtgtatagt
     5461 ttttttattt acacgattta atgtactatt ttttatttta gtattaagaa ctccattaat
     5521 acgattttta aattctgctt caaaaaatcc cttaatttgt tggtgcgcaa gttcaacatt
     5581 caaacctttc ttatacaagt cttcattctg atacaagtct tcattctgaa cgatttcggc
     5641 tacacggtga atggtttgat cgtataccgt cttctcttaa ccagcagtat ccttagtttt
     5701 aatgactact cgataggttc ctttagaacc gttatagtca tctagtttta aaaaagcatt
     5761 ccaaacattc aaaaatagtt ggaacttccc ttaataaatc cgtcactttc tttttcaaga
     5821 tagcccaagc ttgctcaata ggattcaaat ccggtgaata aggtggtaga ggtaagaaaa
     5881 agtgtttatc ttggatgcag agttcatcca aaatgttctt gggatgaaaa ctagcattgc
     5941 ccatgacaat aacatgaggt gtcttcaaag caggtaggag ttgcgttttg aaccactcca
     6001 caaagaaatc gcttgtcatg cttttcttgt aaatcatggg agctataaac tctccgtcta
     6061 cttgtcctgc aacaattgaa gttcgctcaa aacgacgtcc gctaatcttt tcatagactt
     6121 tctcccctct aggagcccct gcataaggac gatagaggta gcggtcgatt cctgtttcat
     6181 caatatatac gattggtaaa tcttttaggt tatccaaaat atcaagaaac tcagcgactt
     6241 tctctgactc ttgttcctta aagatcgtca tcttttttta aagtgacctt aatctgcttt
     6301 aaagctgccc atactgaagg aacagcacaa tcaaaatgtg ccgcaatttc ccgtaaaaaa
     6361 gcatctggat gagcctctac aaaggctttc aattcttcta aagggatctt acgctttttg
     6421 acgactcgct ttttccgctc taagttcctt tgttcacgtc tttcttttcc cacgtgaaga
     6481 gagttctgac gccaacacca aaaaactttg gccgcctcga catgtctgtg ccctcctttg
     6541 atggaatcta atgctccttg tttaaaatca gtattatatg ccatagcttt attagaccat
     6601 gcttatttta aactaagcaa ctatatcaat gttttgttat gagaagactt acttttttta
     6661 ctgaaattga atttttccta gcctcaacat catataaccc caaaattcaa tctgacctgg
     6721 tttgaagaga tgttcgaagc agataaggtt ttactaaaac taaaaaaaat gatataatca
     6781 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
     6841 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
     6901 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
     6961 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
     7021 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtagcaat
     7081 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
     7141 taaacacggc atcaaatctt acgtatttga aagccttcgt ccgactccag aactatcatt
     7201 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
     7261 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
     7321 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
     7381 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacgtaga
     7441 ataccttaaa gaggttaagg acgtaaacat caacccagcc ttgattgaag aatttggtaa
     7501 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttgg ctcgtcgtgc
     7561 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
     7621 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
     7681 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
     7741 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     7801 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     7861 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     7921 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     7981 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     8041 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     8101 acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     8161 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     8221 tgctgaacaa atcaaagaga ttatggctaa attccgcaac aatgctccaa aagaatggaa
     8281 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     8341 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     8401 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     8461 tgtaggggaa accaacgaag aatcacaagc taagattgct aacatcgaag cagaaatcaa
     8521 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     8581 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     8641 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     8701 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     8761 ccttactgcc gtaaatttgc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     8821 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     8881 cgttatggaa tcccaactgt accaggtttt attcatatta cagatggaca aatcaacgtc
     8941 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgcaggatt gtaaaaaatc
     9001 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     9061 tgcgttttat tgttcctaaa acagttacat cagtatttca ttacagaaca ttttaatttt
     9121 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattca
//
LOCUS       DAVLZG010000070         8882 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLZG010000070 DAVLZG010000000
VERSION     DAVLZG010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.070"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(48..2453)
                     /locus_tag="VYO72_001809"
     CDS             complement(48..2453)
                     /locus_tag="VYO72_001809"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1708131.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(2530..3039)
                     /locus_tag="VYO72_001810"
     CDS             complement(2530..3039)
                     /locus_tag="VYO72_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1708132.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(3039..4085)
                     /gene="pheS"
                     /locus_tag="VYO72_001811"
     CDS             complement(3039..4085)
                     /gene="pheS"
                     /locus_tag="VYO72_001811"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1708133.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(4567..5982)
                     /locus_tag="VYO72_001812"
     CDS             complement(4567..5982)
                     /locus_tag="VYO72_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1708134.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(5995..7833)
                     /locus_tag="VYO72_001813"
     CDS             complement(5995..7833)
                     /locus_tag="VYO72_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1708135.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(7851..8690)
                     /locus_tag="VYO72_001814"
     CDS             complement(7851..8690)
                     /locus_tag="VYO72_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1708136.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELAYLMAHIRRLTK
                     NLD"
BASE COUNT         2695 a         1922 c         1463 g         2802 t
ORIGIN      
        1 cctctaatgt tcataaacta gagggggaat ttgtatccta ctatcgttta acgcacttct
       61 gcattcactt tttcttcgag agacgcttgg attttttcca tatagcgtgc gacttcttcg
      121 tccgttaagc tgtcttctgg attttggaag gtcaagctat aagccattga cttcatacca
      181 agtcccagtt tttcacctga gaagacgtca aagagtttga tatctgtcaa acgtttcacg
      241 ccggcagctt ggatagcatc tacaacttct tggtgagtca cttctgcctt gaggagaagg
      301 gcaacgtcac ggctgactgc tgggaatttg gtgatttcca caaatggaac agcaggttgg
      361 agcgcccctt cgatggctga aaggttaagc tcagctacat acgtttctgg aatatcgtaa
      421 gccttggcag tgactggatg cacttggcca aggaaaccaa gaacttggtc accgagtgaa
      481 atcacggctg tacgacctgg atgaaggcta acgatttcag atgttgctgt ataggttact
      541 tggagtccca aacgagtaaa tagggcttca aggattccct tagcatagaa gaaatcaact
      601 ggaactgctg ctgtttggaa atctttttca gcaaccaagc ctgtcaaggc aaaggcaaag
      661 ctgttgatct catttggaag ttcttctttt ggattacctg tttgttcaaa gacttttcca
      721 atctcataaa gggccaagtt tttattctta cgagccacgt tgtaggcaac ggtatcaagg
      781 atccctgaaa tcatattttg acggaggact gaacgatcca cagtcattgg ccacatgagt
      841 tcagtaaggt tacttggttg agctgtgaac tcaactgctt tttcaggagt tgtcagagca
      901 taggtgatga tttctgtcaa acctgctcct tcagcaatgg tacgaacttg acggcggagt
      961 ttttgtatca cagtcaattc accagctgta ccatcgtctt ttggaaggct ggttggcaag
     1021 cggtcatatc catagatacg agcgatttct tcaaagagat cagcttcgat tgtgatatcc
     1081 caacgacgac gtggtacgct gactgtaaag ctgtctgcat ttccagaaag accaaagcca
     1141 agacgacgga agacgtcttc tacatcagca taagacagct cagttccgag gacacggtta
     1201 acatcagcaa gggttgaaga aacttccaca tcagaggtat caagctcacc cgctgaaacg
     1261 atacccttac gcaccgtcgc gcctgcaagc tctgcaatca tgctagctgc cgcatcaagg
     1321 gcttcattaa ctgttgccac attaattcct ttttcaaagc gagaagatga ctcagaacga
     1381 aggttcaggc gaccacttgt cttacggata gatttgccat taaaaacagc agcttcaagg
     1441 ataacacgac tagatttttc agaaatttct gtagcctgac cacccataac accggcaagg
     1501 gctactggtt tgtcagcaac tgtaatcacg aggtctgtct cagccaagtc tcgttcttca
     1561 ccgtccaggg tcactaattt ttcaccatca cgcgcttcac gcacacggat gtcagtccct
     1621 tcaaatgtgt ccaagtcaaa agcatgcata ggttgaccaa agtagagcag gatgtagttt
     1681 gtcacgtcta caacgttatt gatgggacgg atgccttcgt tcatgagaag gttttgcaac
     1741 cattgtggac ttggtgcgat agtcacattg tccaagatac gagctgcata gtaaggcgcc
     1801 ttgtctgtct caatgctgac agaaagggca tctgccgcag cttcattagt ttctgttaga
     1861 gtaaattttt taaagttgac tgccttgtca tagatggctg ccacttcgtg agccactcca
     1921 cacatagaaa gggcatctgc acggtttggt gtgatggaaa gttcgatgat ttcatcatcc
     1981 aagtctaggt aagaaaagac ttcctcacct ggcacggcat cttcaggcaa gatttggatg
     2041 ccatctgcga attccttagg cacaactgag tcagaaattc ccaattcacc aagtgaacag
     2101 atcattccaa gtgactccaa accacggatt tttccttttt tgattttgta gttatcagcg
     2161 atacgagctc ctggaagagc caccatgacc ttgatcccag cacgcacatt tggggcacca
     2221 caaacgatct gacgctcttc ttcttcgcca acgttaatct gacaaacatg gaggtgagtc
     2281 tctggcacat cttcgcaaga caagacctca ccgacgacaa tttttgagag accagcagct
     2341 ggtgattcga caccctctac ctcgatccct gtagttgaca ttttttcagc caactcttgt
     2401 gatggcacat caatgtccac caattctttt aaccatttat aagatacaag cataatttag
     2461 ttctccagaa tgacagttgt cactctagtt cttttccttt cctatcattt caatagaaga
     2521 atcctcttct taccttaatt tctttctcag taaccaatcc gtatctactt tttgaccaac
     2581 cataaaatga tgttggctaa atttttcaaa accatatcgg ttataaaacg cttgagcttt
     2641 tgtattatgc tcccaaacac ctagccaagc ccaagaaaaa ctattttttg tagcaagttc
     2701 aagtgcgaat tcaaacagtt gcttacctag tccaaatcct tggaattttt gtagcacata
     2761 gaggcgttga atttcaaaag cgtcctctaa ttctctctca gtttgagcac ttccccagtt
     2821 gactttgaga aaaccagcta tctcctcctc atgcataatg aaataggttt cagagtcagg
     2881 atttcccaac tcagttgaca aagttttcag actataagcc tcttcaaagt attcctgtaa
     2941 ctgctcttcc gtattatcat acgcaaaggt ttcacgaaag gtttgtttgg caattttagc
     3001 caacacctca acatctgcca tttctacttt tctaatcatt atttaaactg ttctgagaag
     3061 cggacatctc cttggtagaa tccacggata tcgttgattc cataacggag catagctaca
     3121 cgctcttgtc caagaccaaa ggcaaagcca gagtatacag tcgcatcgat accactcatt
     3181 tcaaggacac gtgggtgaac cataccggcc cccataattt cgatccaacc tgttttctta
     3241 catacattac agccttctcc accacacttg aagcaagaaa catccacctc aacagatggc
     3301 tctgtgaatg ggaagtaaga tggacgcaaa cgaatttgac gctcttcacc aaacattttt
     3361 tggacaatca actgaagcgt tccttgaaga tcagccatag agatattttt cccaactacc
     3421 aagccttcga tttggtggaa ttggtgactg tgggtcgcat cgtccgtatc gcgacggaag
     3481 acacgccctg gcgagatcat cttcaaagga cctttagaaa aatcatgggc atccatagca
     3541 cgcgcctgaa ctggagacgt gtgggtacgg agcaagattt cttcagtgat atagaaagta
     3601 tcctgcatat cacgagctgg gtggtctttt ggaaggttca tacgttcaaa gttatagtag
     3661 tcttgctcca cttcaaaacc atccacgact tgataaccca taccgatgaa gatatcttcg
     3721 atttcttcac tggtttgtgt caaaacgtga cggtgaccag tcgcaactgg acgacctgga
     3781 agcgtcacat ctatactctc gctagccagt tgagccgcga ctttcttttc ttccaagagc
     3841 ttagctgttt cttcaaaagc agcagtcaag acatcacgag cttcattgac gtgtttcccg
     3901 atgattggac gcatctcagc agaaacatct ttcatccctt tgaggatttc agtgagcgaa
     3961 ccctttttac caaggacaga gacacgcaaa tcttgcatct ctttttcatt tccagcagta
     4021 atctgcttca agctagccag cgtttcttcg cgaagcgctt ttaattgttc ttcaatagtt
     4081 gacatatttc ctccatcagt ctctcgtaga taaaaagaaa accacatgcc aaaaactcca
     4141 ctcggagcgt tgacacgcgg taccatccgt tttcatctga caagtcagac cttcatttct
     4201 aaatccatgc gcaagtgaat tcacccagct ttcatataga gagcttgcag tcacggctct
     4261 cctccctgat atacttccct tgggctacta gtctttcaga ttcctattca attactactt
     4321 agtttatcag atttttacca ttcttgcaag acctatctta cttctgcttg ttagcttatt
     4381 cttatctaaa tttatataaa caatttatct aaattaacta tttataattt ttgtaacaaa
     4441 attaaattaa ttgacactcc cctataaaat aaagaagttt agaatttaat gtcttccaaa
     4501 cttctttatt ccatatttaa tgaaatgcca ccttaaccgt gataatagct agtcatcaat
     4561 aaaaaactat ttgaataagg attctccatt tgattcaatc acttctttat accaagtaaa
     4621 agacattttc ttatatcgat ttaatgtacc acttccatca tcgtttcgat caacataaat
     4681 gagaccgtac cttttagaaa gttgtgcagt ggacatagaa acacagtcaa tacatcccca
     4741 agacgtatag cccataattt caacaccatc ctgtagagct tcagcaactt gcaataaatg
     4801 ttctttcata tactgaattc tataatcatc ttggacggtt aagttattaa gttcatcttt
     4861 tattagttga tctttagcac ctaatccatt ttctactata aataatggga tttgataacg
     4921 gtcataatat ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc
     4981 tgaagactct aaataaggat ttactaaacc accaataata ttcccttctc ctgaattata
     5041 ctgtgttgga agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac
     5101 ggtataattt tttaataact ctgcatcttc agctgcaaac tctatgttaa tgtcattttc
     5161 cttaaaatat ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag
     5221 ataatttaga ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg
     5281 ataagctggc atagctaata ccatacatcc caccttaaac tctgaattaa tctcacgagc
     5341 aatttttgta accaaacttg aggcgactaa ttcatgatgt atagcttgat ataattcttg
     5401 tttcgaaaga ttctccttag gtatatctat tcctccacta gtaaatggta attccaaaac
     5461 agagtttact tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac
     5521 tgttcgagca aatttttcat aaaaatgaat cattctccta tcaacccatc catgatattt
     5581 tcttgctaaa tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg
     5641 agcatgtagt tcatcaaaca attcatcata atatttcaac ccagcttcgt taggttcttc
     5701 ctcatctcct tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc
     5761 catttcagaa aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa
     5821 ttttaagtta tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac
     5881 atcctgaact gataagccct taccatcttc attatatgct ccctctactt gattagctgc
     5941 aacagctcca ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa
     6001 tattaccagt aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc
     6061 tagaaaatca ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt
     6121 gattaaattc aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc
     6181 tacatgacta ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag
     6241 taactcaaca ccctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt
     6301 aattttccca tcaaatggtg cataaacctt accttcactt gggataatcg ctactccgtc
     6361 tccaattagt ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc
     6421 tgatatagga gaaaatatca tttttttatt tgaaactcca gcttcaactt ctaaattgct
     6481 agaactctct tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga
     6541 aatgaccgcc acaattaaag catttacaat atttgatggc acatcagaat aaataaattg
     6601 aggcaacgct atcaaagatg ggacagcaaa tagatatgct ttaacactag taagacctgc
     6661 aaataatccc gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa
     6721 agtcacacca tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc
     6781 aaaagcaatt tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc
     6841 cccttgagct aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat
     6901 agatgccgcc aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg
     6961 cataatagca ccaagaatag ctaatgtaag ccatccagct acaccataca tttgcccaac
     7021 tagatttgat aatccttcac caacaattac tccaataggt ccgactacaa ctaaggcaat
     7081 acagcttgat actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa tagctagtgt
     7141 taatttagca attatttttt caatatattt catcaaccaa accataataa gaattggaac
     7201 gactgatgaa ccataactag ctggtgtcac aggtgcacca aataaactaa gaggattccc
     7261 tgattgcacc atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa
     7321 tgtagatgtt acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata
     7381 atatggagca tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat
     7441 accaagcatt ggtaaaatga ttaccaagac tttcaacata cctcccccta acattgctgg
     7501 aatgattgga gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt
     7561 gtgcccttga acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata
     7621 attagctaca tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat
     7681 tacacctggt atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa
     7741 tcttaaacgt gttacacaat gggtaactct attgacattt ttttcacctc caattacatc
     7801 gaggattttt tgtaccgtat ctttataact catggtattc tcctattcta ttaatctaaa
     7861 ttttttgtta agcgacgaat atgagccatc aaataagcta attcactaga agtcagcaaa
     7921 taattgtact ccgtttgtat aaacattgct acctgttcac cacattcata ttctctagga
     7981 tatttatttt tcattaatgc taacaagtct tcatcatcat cgtcacaata agttgtattt
     8041 tcaaccaagc gatgggcaaa taattttata tgagttatga atctataata atcaatagaa
     8101 tcttggttaa actcagtaca atagaaatct tgaatgattt tctcaattcc cataattatt
     8161 tcagtgattt tatacgactc ttgaaaatta ttttctaaat tagcattaac aaaatgtagc
     8221 gctatgaatg cagcttcgtc aattggaagt tcaataccta actctttttt tattatttgt
     8281 aaagcccttt tcccaagttc aaattcttct ttataatatt tcgatatttc ccagcgtagg
     8341 ggattcgaaa taataatccc ttctttataa cgttctatgc tcgaagaaat atgatccgtt
     8401 aaattaatat agataatttc atcaaaatta ttacccaatg ttattttacc taggttaatt
     8461 attttttcgg tgatgtacac caactccaaa ggaacgttaa taaacatctc tgtaaaacgg
     8521 gtcatattat ctctattttt gagaaaaaaa cttttctcaa tatcaattgg atttacttta
     8581 tctccagttt ttcttccaaa agctattccc cttccaaaaa gaagaatatc gatatctttt
     8641 ttactttgcg caattacggc attgtggttt agtattcgtt ttatgatcat aaaatttccc
     8701 ttttaaaata aaaggaacct acttaaaaac atcaagaaac ttcttctgat gtgattaaat
     8761 aggttcctgc tcacttgtat tagtgataac atccttttat ttcaattttt aatggtgaca
     8821 tgaagcttaa ataattaata actctgtaac cgtttttatt ttatgatatt tcaatctatt
     8881 tg
//
LOCUS       DAVLZG010000071         8765 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLZG010000071 DAVLZG010000000
VERSION     DAVLZG010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.071"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            44..199
                     /locus_tag="VYO72_001815"
                     /pseudo
     CDS             44..199
                     /locus_tag="VYO72_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            399..3674
                     /gene="rexB"
                     /locus_tag="VYO72_001816"
     CDS             399..3674
                     /gene="rexB"
                     /locus_tag="VYO72_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1708137.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTDYLNQ
                     GQLAQRSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYCFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLDQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3671..7321
                     /gene="addA"
                     /locus_tag="VYO72_001817"
     CDS             3671..7321
                     /gene="addA"
                     /locus_tag="VYO72_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1708138.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEVYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYIFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLTSLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7491..8669
                     /locus_tag="VYO72_001818"
     CDS             7491..8669
                     /locus_tag="VYO72_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708139.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERDIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2710 a         1845 c         1865 g         2345 t
ORIGIN      
        1 ctatttttgg ttcattttac tatagttcaa tcattctatc aagaatattg aatatataaa
       61 ggcacgtaat attaaaactt cttctgatat cgaattagag tccgatgttg atggcgataa
      121 atcagacaat ctacccgtcg acattaagac actgggacaa cacattgaag tgtattccgt
      181 acctaagaaa caatcataaa actcaaagcc ttgttaccga ggctttttta ttatatgatt
      241 ttcagtggcc agacttattc tatctaatac aagtaaagct aagtatttaa gatttagcag
      301 atgatgaaga aaagaaagga tggcctaaat attttaacag atttacgagg ctaatcatgg
      361 tataatatag ggtgatgaaa aattccaacg aggctgagat gaaattactt tatactgata
      421 ttcgaacttc tttgacagaa attctaacaa gagaggcaga agagctagtt gcagctggca
      481 agcgggtctt ctacattgcc cccaactctc tttcttttga aaaggaacgc gccgtgctgg
      541 aatgcttgtc ccagcaggct tctttttcga ttaccgtcac gcgctttgct caaatggctc
      601 gttatctggt cttgaatgat ttaccagtta aaactactct tgatgatatc ggtcttgggt
      661 tggcctttta caaatgcctt gccgaactcg atcccaagga cttgcgtgtt tatggagcta
      721 ttaagcagga tcctcaattg atccagcagt taattgagct ttaccatgag atgaccaaat
      781 ctcagatgaa ttttttggac ttggagaatt taacagatga ggataagagg gcggatttac
      841 tcttgatttt tgagaaagta acagactatc ttaatcaagg tcagttagcc cagagaagtc
      901 agttgtccca tttgattgag gctattgaga atgacaaggt aagtagtgat tttaatcaaa
      961 tcgccttggt cattgacggc tttactcgtt tttctgctga ggaagagcgg gttgtggact
     1021 tacttcacgg caaaggtgtt gagattgtta tcggggctta tgctagtaag aaagcctata
     1081 ccagtccttt tagcgagggc aatctctacc aagccagcgt aaaatttctc catcatctgg
     1141 cttctaaata ccaaacgccc gctcaggact gttctcaaac tcatgagaag atggatagtt
     1201 ttgacaaggc ctctcgtttg ttggagtctt cttatgactt ttcagaactc gctttggatg
     1261 tcgatgagaa agaccgtgaa aatttacaaa tctggtcttg tttgacgcaa aaggaggagt
     1321 tggagctagt agcccgtagc attcgtcaga aattacatga gaactcagac ctgagctaca
     1381 agcattttcg tattctcttg ggggatgtag cttcttacca gttatctctc aaaaccattt
     1441 ttgaccagta tcagattcct ttttatcttg gtagaagcga agccatggct catcatccct
     1501 tgactcagtt tgtcgagtct attttagctt taaaacgtta ctgttttcgt caggaggatt
     1561 tgattaatct tcttagaact gacttgtata ctgacctcag tcagtctgat attgatgctt
     1621 ttgagcaata tatccgctat cttggtatca atggcttgcc agcctttcag caaatcttca
     1681 ccaaatccca ccatggaaaa tttaatcttg agcgtttgaa tgtcctccgc ctgagaattt
     1741 tagcacctct tgaaaccctc tttgccagcc gaaaacaaaa ggctgaaaac ctcctacaaa
     1801 aatggagtgt ctttctaaaa gaaggagctg tgaccaagca gttacaagat ttgacaacca
     1861 ctttggaagc tgtagaacag gaaagacaag ccgaagtttg gaaggctttc tgccatgttt
     1921 tagaacaatt tgcgactgtt tttgctggtt cacaggttag tctggaagac ttcctagcct
     1981 tgctccattc tggaatgagt ttgtcccaat accgtaccat tccagcaaca gtggacactg
     2041 ttctggtgca gagttacgat ttgattgcac cattgactgc tgactttgtc tatgctattg
     2101 gactaactca ggacaattta ccaaaaattt ctcaaaacac cagtcttctg acagatgaag
     2161 aaaggcaaaa tctaaaccaa gcgaccgaag aaggcgttca attactgatt gccagcagtg
     2221 aaaatctcaa gaaaaatcgc tacactatgc tttccttagt caattctgct cgtaagcagt
     2281 tgttcttgtc ggctccaagc ctttttaacg aaagtgaaag taaggaatct gcctatcttc
     2341 aagagttgat ccattttgga tttaggcgga gagagaagag gatgaatcac aaaggactgt
     2401 ctaaggagga tatggggtcc tatcacagtc ttttgtctag tctggttgcc tatcaccagc
     2461 agggtgagat gagcgatact gagcaagatt tgacttttgt caaggttctg tcgcgtgtca
     2521 taggtaaaaa actagatcag caaggtctgg aaaatccagc catcccaatc agtccaagca
     2581 gcaagacctt agccaaggac accttgcaag ctctctatcc tgccaaacag gagttttacc
     2641 tgtctacgtc gggtttgaca gagttttatc gcaatgaata cagttatttc ctacgctacg
     2701 ttttaggctt gcaggaggaa ttacgtttgc gtcctgatgc ccgtagtcac gggaatttct
     2761 tgcatcgtat ctttgaacgc gccttgcagt tgcctaatga agattccttt gaccaacgtc
     2821 tagaacaagc tattcaagaa accagtcaag aacgcgaatt tgaagctatt tatcaagaaa
     2881 gtttggaagc ccagtttacc aaggaagttt tgcttgatgt tgcacggaca actggacata
     2941 ttctccgaca caatccagcc atcgaaacaa tcaaagaaga agcaaatttt ggtggaaaag
     3001 accaagcctt tattcaatta gacaatggac gcagtgtctt tgtacgaggc aaggtggacc
     3061 ggattgaccg tttgaaagct aatggagcga taggagtagt agactacaaa tccagtctga
     3121 ctcagttcca gtttcctcat ttctttaatg ggctcaattc tcagttacca acctatcttg
     3181 ctgccctaaa aagagaaggg gagcagaact ttttcggcgc catgtacttg gaaatggctg
     3241 aacctgtcca atctctgatg gcggtaaaaa gtctggcagg agcagtggta gaagccagca
     3301 aatctatgaa ataccaaggg ctcttcttgg aaaaagaaag cagttattta ggcgaatttt
     3361 ataacaaaaa caaggcgaat caactgacag atgaggaatt tcagctccta ctggactaca
     3421 atgcctatct ttacaagaaa gctgctgaga agattttagc aggccggttc gccatcaatc
     3481 cttatactga aaatggcaga agcattgccc catacgtcca gcaacatcag gctattacag
     3541 gctttgaagc caattaccat ctggaccaag cccgtttcct agaaaagttg gacctagctg
     3601 atggcaagcg tctggtcgga gaaaaactca agcaagcttg gcttgaaaaa ataagagagg
     3661 agttgaatcg atgaagctta ttcccttttt aagtgaggag gagattcaaa aactgcaaga
     3721 agcagaagca aattcgagca aggaacagaa gaaaactgcc gagcaaatcg aagctatcta
     3781 cacttctggc cagaatatcc tggtctcagc atcggctggt tctggaaaga cctttgtcat
     3841 ggcagagcgc attctggacc aattggcgcg tggtgtcgaa atttctcaac tctttatctc
     3901 aacctttacc gtcaaggctg caaatgaact taaagaacgt ttagagaaaa aaatcagcaa
     3961 gaaaatccaa gaaacagatg atgtcgacct caaacaacac ttgggacgcc agttggcaga
     4021 cctaccaaac gctgccatcg gaaccatgga ctctttcaca caaaaattcc ttggcaaaca
     4081 tggttatctg cttgatattg cacctaattt ccgtatttta caaaaccaaa gcgagcaact
     4141 tcttctcgaa aacgaagtct ttcatgaggt ctttgaagcg cattaccaag gtaaacagaa
     4201 agagaccttt agtcatttgc tgaaaaactt tgctgggcgt ggcaaggacg aacggggtct
     4261 gcgccagcag gtctataaaa tctatgactt cctccaatcc accagtaatc ctcaaaagtg
     4321 gctgagtgaa tctttcctca aaggctttga gaaagctgat tttaccagtg aaaaagaaaa
     4381 actgactgag caaatcaaac aagccctttg ggatttggaa agctttttcc gttaccatct
     4441 ggataacgat gccaaggagt ttgcaaaggc tgcctattta gaaaatgttc agttaattct
     4501 ggatgaaatt ggctccctaa atcaggagtc cgatagtcag gcttatcagg cagtgcttgc
     4561 gcgtgttgtc gccatctcta aggagaaaaa cggtcgagct ctgactaatg ccagtcgtaa
     4621 ggctgatttg aagcccctgg ctgatgccta caacgaagag agaaagaccc agtttgctaa
     4681 actaggacaa ttatcagacc agataaccat tctcgactat caagaacgtt atcatcaaga
     4741 cacatgggaa ctagctaaaa ccttccaaac ctttatgagt cattttgtgg aggtttatcg
     4801 tcagcgcaaa cgccaggaaa atgcctttga attcgctgat atcagccatt acaccattga
     4861 gattttagag aatttcccac aagttcgtga gtcttatcag gagcgcttcc atgaagtcat
     4921 ggtcgatgag tatcaggata ccaaccatat tcaagaacgg atgctggaat tgttgtctaa
     4981 tggccacaat cgctttatgg tgggagatat caagcaatcc atctatcgtt tccgtcaggc
     5041 agacccgcag attttcaatg agaaattcca acgctatgcg caaaatcccc aagaaggcaa
     5101 gctcattctc ctcaaggaaa atttccgtag tagttcagaa gtgctgtcag caaccaatga
     5161 tgtctttgaa cgtctcatgg accaagaggt cggcgaaatc aactatgata acaagcacca
     5221 gcttgttttt gccaatacca aactgactcc caatccagac aacaaggcag aatttctcct
     5281 ctacgacaag gacgatacag gtgaggaaga agagagtcaa acagaaacga aactaacagg
     5341 cgaaatgcgc ttagttatca aggagattct gaaacttcat caagaaaaag gtgttgcctt
     5401 taaggaaatt gcccttctga cctccagccg cagtcgtaat gaccagattc tcctcgccct
     5461 gtctgagtac ggaattcctg tcaaaactga cggagagcaa aacaattatc tccaatccct
     5521 agaagtgcaa gtcatgctag acactcttcg tgtcattcac aatcccctgc aagactacgc
     5581 cttggttgcc cttatgaagt ctccaatgtt tggttttgat gaggatgagc tagcacgttt
     5641 gtcccttcag aaagcagagg ataaagtcca cgaaaatctc tatgagaaac tggtcaatgc
     5701 acaaaaaatg gcaagtagtc aaaaaggctt gattcacaca gctctagctg aaaaactaaa
     5761 gcaattcatg gatatcctag cttcttggcg cttgtatgcc aaaacccatt ctctctatga
     5821 cttgatttgg aagatttaca acgaccgttt ttattatgac tatgttgggg ctttgccgaa
     5881 tggtcctgct aggcaggcca atctctatgc cctagcactg cgtgctgatc aatttgaaaa
     5941 gagcaatttc aaaggtttgt cgcgttttat tcgtatgatt gaccaagtct tagaagccca
     6001 gcacgatttg gcaagcgtag ccgtcgcacc gccaaaagat gcagtagagc tcatgaccat
     6061 ccacaagagt aaagggctgg agtttcctta catctttatc ctcaatatgg atcaagattt
     6121 caacaagcaa gactctatgt cagaagtcat tctcagtcgt cagaatggtc ttggtgtcaa
     6181 atatattgcc aagatggaga caggggcagt agaagaccac tatcctaaaa ccatcaaact
     6241 ctccattcct agtctgacct ataggcagaa cgaagaggaa ttacagctag caagctattc
     6301 tgagcagatg cgtttgctgt atgttgctat gacgcgggct gagaaaaagc tctatcttgt
     6361 cggcaagggt tctcgtgaaa agctggaatc caaggaatac ccagcagcca aaaatgggaa
     6421 actaaatagc aatactagac tgcaagcacg gaatttccaa gattggcttt gggctatcag
     6481 taaagtgttt actaaggaca agctcaactt tagttatcgt tttattggcg aagatcagtt
     6541 gaccagagaa gctatcggag agttggaaac caagagtcct ctccaagata gctcccaagc
     6601 agacaatcgt cagtcagata ccatcaaaga agctctggaa atgctgaagg aggtggaagt
     6661 ttataatact cttcaccgcg cagctattga acttcctagt gttcaaaccc caagtcaaat
     6721 caagaaattc tacgaaccag ttatggatat ggaaggtgtc gagattgctg gtcaaggtca
     6781 gtcagtaggc aagaaaatca gcttcgattt gccagatttt tcaaccaaag aaaaggtaac
     6841 tggagctgag attggtagtg ctactcacga actcatgcag agaattgacc tcagccagca
     6901 actaaccctt actagcctaa cagaaacact caaacaagtt caaactagcc aagctgtcag
     6961 agacaagatc aatcttgata aaattcttgc tttctttgac acagcactcg gtcaggaaat
     7021 tcttgctaat accgaccatc tctatcgcga gcaacctttc tccatgctca aacgagacca
     7081 aaagagtcag gaagactttg ttgtccgtgg tatccttgat ggctatctgc tttacgaaaa
     7141 caaaattgtt ctgttcgact acaagacaga ccgctatgat gaaccaagtc aactcgtaga
     7201 ccgctatcgt ggtcagttag ctctatacga agaggcttta tcacgagcct attcgattga
     7261 aaatattgaa aaatacttga ttttactcgg taaagacgag gttcaagttg taaaagtata
     7321 acttatactc ttcgaaaatc tcttcaaacc acgtcagctt cgccttgctg tatatatggt
     7381 tactgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg actgcggcta
     7441 gctttctagt ttgctctttg atttttattg agtattagaa aggagacctc atgacacttc
     7501 cagttagaaa atccctgcac gatgcagttt tacaggcttc gaaagcggat acttgggaac
     7561 aagctaccaa ggaatggaat gaagtttcct tgatttttaa cggtatcggc cgtagcaatt
     7621 gtgtctgtgg aaatgccatc aaatacgctt atgaactctt taacggtgtc acaggccaac
     7681 gcctctttcc aattggtagc gactgtgttc gtcattttca tcgattgtcc cttgaccagc
     7741 aattggaaga ggaagaaaaa ctgctcagaa aggttgaaaa tctaaccaga aaagctcaga
     7801 aaaaggaaaa aatcaaggtc aataaaagtg actttgacga gcgacttcta aaatggctct
     7861 gggaaaaagg tgttttcaaa cccaatcgtg gcaatcaatt tgcgcctgag agagactacc
     7921 agcttttcct agaagtcttt cagggaggaa gttggaccaa ggcggaacca aagaaaaagg
     7981 ctcggatgga agaagtcctt gaaaagtgta tcaaaccctt tttacttggg aaatcggatg
     8041 accaactcta ccttgtcaag ctaggcaagg agaaaattga ctacgaacaa gaactccgta
     8101 tccaggcaga gaaagaacgc aagaagaggg ataaaatcgc caagcaatat gcagacaatc
     8161 tggttctagc catgggaccc gcagagcgtg cttatcaaga ttactttggc tttacagaga
     8221 ccctgactca agaagaacgc aagtgggaaa aaattctttt tggtaaaaat agagcagaac
     8281 gggatatcaa ggccaaacaa taccaaaaag agctggaaaa agaccaacga attgccagtc
     8341 aggatccaat tgaaagaaaa cagaagcaga cttggctcct caattcctat tttcgtgagc
     8401 ttcctgaaga aaaagctcga ttttctaggc tcttattaga atatcgaaaa agtggtgaag
     8461 tacccttttc aactgaatac ctgtccgatc atctcatcga ctttttctat aaaatgaaag
     8521 cctttgaatt tgaaatcgca ccagaacaag tccgagattt tctaaaaaaa agcctgcagg
     8581 aagaccatcg ctcatcagca caaggaagct ggatagaagg aattctcctc aactgcctca
     8641 aaccattttt agaacgatta gtgatatgag taacacctac cgtgtaaatt tcatggtagg
     8701 tgttattgta cctcaaaata atataaaaca aagtatgaaa gcgcatctca attttaagac
     8761 ttttt
//
LOCUS       DAVLZG010000072         8059 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLZG010000072 DAVLZG010000000
VERSION     DAVLZG010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.072"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            13..1488
                     /gene="galT"
                     /locus_tag="VYO72_001819"
     CDS             13..1488
                     /gene="galT"
                     /locus_tag="VYO72_001819"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1708140.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1501..2511
                     /gene="galE"
                     /locus_tag="VYO72_001820"
     CDS             1501..2511
                     /gene="galE"
                     /locus_tag="VYO72_001820"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1708141.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2691..3350
                     /locus_tag="VYO72_001821"
     CDS             2691..3350
                     /locus_tag="VYO72_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1708142.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3375..4442
                     /locus_tag="VYO72_001822"
     CDS             3375..4442
                     /locus_tag="VYO72_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1708143.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4546..5556
                     /locus_tag="VYO72_001823"
     CDS             4546..5556
                     /locus_tag="VYO72_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708144.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5568..7259
                     /locus_tag="VYO72_001824"
     CDS             5568..7259
                     /locus_tag="VYO72_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1708145.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLSSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7262..7972
                     /locus_tag="VYO72_001825"
     CDS             7262..7972
                     /locus_tag="VYO72_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1708146.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2718 a         1133 c         1584 g         2624 t
ORIGIN      
        1 aaagaaaaat atatgaaaac aattattgat aattttgttg atagagtaat tgaatacgga
       61 atgtataatg aaattgacaa aatatatgtg aaaaatagag tactagcgtt aataggtgag
      121 gagggaactg atcgcatttc cgatgaaaat gacctgaaac aaataaaaga ttacttagtg
      181 gaaatcgcct taaaaaacgg taaaattaaa gatttaatcg aggaaaagga atgtttagga
      241 gcagagttaa tgaatttcat agttccttta cctagtcgat taaatgatat tttttggagt
      301 tcatatgata tatcacctca agaagcagtt gaagagtttt ataagttaag taaagatagt
      361 gattatatta aaacttctgc tattgctaag aatattgagt ttcgagcatc aactaaatac
      421 ggagagctag agattacgat aaatttgtca aaacccgaaa aagatccaaa aacaattgct
      481 gctgaaaaat tagtaaaagc cactaattat cccaaatgtt tactatgtat ggaaaatgaa
      541 ggatatcagg ggcgaataaa ttatccagca cgttcgaatc atagaattat tcgattgaaa
      601 cttggtgacg aagtatgggg attccaatat tctccctact tatactttaa tgagcatgcg
      661 atatttttaa atagtcaaca tgtaccaatg gctattacct ctaaaacatt tgaacaatta
      721 ttggagattg ttgatatttt gccaggatat tttgctggtt caaattctga tcttcctatc
      781 tcaggaggct ccattcttag tcataaccac taccagggag ggaaacatat tttcccaatg
      841 gaaaaagcaa aatttgagag tgaatttcgt tttaaagact ttgaggatgt taatgctggt
      901 attgtaaaat ggccaatgtc agtaattagg ttacaaagtg aaaataaaaa tcgcttgtta
      961 gatttagcta ctaaaattct aaataagtgg agagaatatt cagatttaga agtagacatc
     1021 attgctatga ctgaagatgt cccacaccat acggtgactc ctattgctcg taaagtggac
     1081 gggagatatg aattagatat tgttctaaga gataatcata ctactgaaca gtacccagat
     1141 ggtgttttcc atcctcatca agatgtacaa catattaaaa aggaaaatat cgggttaatc
     1201 gaagtgatgg gacttgcgat attaccacct cgtttgaaac cagagttaga agaagttgga
     1261 aaatatcttt taggagagga taacgcaatt gcggattatc atttagaatg ggccgaccaa
     1321 ttgaaagaaa aatatcctcg cattaataaa gaagaggtta atagcgtagt tcaacacgaa
     1381 gcaggacaag tgtttgcgag agttctggaa gatgcaggag tttataagaa tacaccgtct
     1441 gggcatgaag cgtttatgag atttgttaag tcggttggaa ttaattagga ggaaacaaaa
     1501 atggcaatat tggtaacagg cggagctggt tatattggta gccataccgt agtagaatta
     1561 ctaaatttag gaaaggaagt catcattgtc gacaaccttt cgaactctag catcttggtg
     1621 ctagaccgta ttgaagcaat tacaggaata cgtcccgtgt tttacgaatt agatgtttgt
     1681 gataaaccag cattgagaaa ggtatttgaa caagaatcga ttgatgctgc aattcatttt
     1741 gcaggttata aagctgtcgg agaatccgtg caaaagcctg tgatgtacta caaaaataat
     1801 attatgagta cattggcact tgttgaagtg atgtcagaat ttaatgttaa aaagattgtc
     1861 ttttcttcaa gtgcgactgt atatggaatt aacaatcagt cacctctaat tgagactatg
     1921 caaacaagtg cgacaaatcc ttatgggtat acgaaagtga tgcttgagca aattttaaaa
     1981 gatgttcatg tggcagattc agaatggagt attgcgttgc ttcgttattt caatccaatt
     2041 ggtgctcatg agtctggttt gattggggaa gatccctcag gaattcctaa caacttgatg
     2101 ccctatattg cacaagtagc ggtaggtaag ctgtcagaac taagtgtgtt cggaaatgat
     2161 tatgatacgc ttgacggtac tggtgtgcgc gattatatcc atgtagtaga tttagcaata
     2221 ggacatataa aagctttaga aaaagtatct gaaaaaacag atgtttatat ctataaccta
     2281 ggctcgggag aaggcactag tgtattacaa cttgtaaata catttgaaag tgttaataag
     2341 atccctattc cttataaaat agttccaaga cgttcaggag acgttgcaac ttgttatgca
     2401 aatgcagaca aagcatataa ggaattaaat tggaggacaa caaaatcgat tgaagacatg
     2461 tgtagagata catggaattg gcaatcaaaa aatcccaatg gctataattg atgatactgt
     2521 ctatatgagt gctgtatttt ggaaaaatta cttaaccttt taatgaaatg catatttaat
     2581 gaaagataaa ttaaaaaaaa tgtttgacag cgcttgacaa aggaaacggt ttcattgtat
     2641 aatgtaaaca caatgacacc gatgtcaaat ataaaaaaga aggtctttat atgaaaaact
     2701 taacaaaaat taagttcaaa gaaaatgggg aatttaatca tttccctggg aatacagttg
     2761 tagcaaatct ttatactaaa caagatttga tggaagttgt tgatattatt caatcacgtt
     2821 atagagaatt accatttatc gataagttta ctttaactcc aaggaattct attcacatga
     2881 ctgtaattga attgttgtgc catgaaaatc gtgaaacgga gttttggagc agtaatcttc
     2941 ctctagatac acctttacag gaaatacatg attactttgc taaacaactt gaaatttttc
     3001 cattgttgga tgaagaaatt catatgcgta taactgaaat gggaaaacaa aacatactag
     3061 ttgaacctgc agatgaagct tctgcaaaga gattagaaga aattcgtact tatgtctcag
     3121 aaaaagcagg tgtttgtttc cctaatcatg atagatatca attccatatt tcaattgggt
     3181 atcttcggat tcctctaacc gaagaggagg aagaagagtt tactaaagtc agagcagaat
     3241 taactgaaat tttattagag aagattccaa ctattactgt aaaccgtatt gactatactg
     3301 tatttgaaga tatgaggcaa tttgttccat atcacgaaaa atttaaataa aataataaaa
     3361 aaggagaact tatcatgaaa aaaatgaaag tttggtctac tgtacttgca acgggagttg
     3421 ctcttactac acttgctgct tgctctggag gttcaaattc tacgactgct tcttcatctg
     3481 aagaaaaagc tgataaaagt caagaattag ttatctattc gaactcagtc tcaaatggtc
     3541 gtggtgattg gttaactgct aaagcaaaag aagctggttt taatataaaa atggttgata
     3601 tcgctggcgc tcaattagca gaccgtgtta ttgctgagaa gaataatgca gttgcagata
     3661 tggtatttgg aattggtgct gttgactcaa ataaaattag agatcaaaaa ttactagtac
     3721 agtacaagcc taaatggtta gataaaattg atcaatcttt atcagataaa gataattatt
     3781 ataatcctgt gattgttcaa ccattagttt taattggggc gcctgatgta aaagaaatgc
     3841 ctaaagattg gactgaatta ggtagtaagt ataaaggtaa atattcaatt tatggtcttc
     3901 aaggtggtac aggacgggca attctagcaa gtatcttagt tcgttacctt gatgaaaaag
     3961 gagatttagg cgtatcagaa aaaggatggg aagttgcaaa agaatacttt gcaaatgcct
     4021 atactcttca aaaaggtgaa agctcagttg ttaaagcgtt agataaagaa agcccaattc
     4081 aatacggtat gatctggggt tctggagcgt taattggaca aaaagaacaa aatgttgaat
     4141 tcaaagttat gactcctgag attggtgtac catttgtaac tgaacaaact atggttttaa
     4201 gcactagtaa aaaacaagcg ttagctaaag aatttattga ttggtttggt caatcagaaa
     4261 ttcaagtaga atatagtaaa aaatttggat ctattcctgc caataaagat gccctaaaag
     4321 agttacctga agatacgaaa aaatttgttg atcaagtgaa accacaaaat attgactggg
     4381 aagctgttgg aaagcatttg gatgaatggg tagaaaaagc tgaattagaa tacgtaaaat
     4441 aagaaataag agttattttt tatgtccaag tctctctatt atttctaaat ttaaggaaga
     4501 aataaagaga ggcttttggt tttagtaata gagggagtta gtgagatgat taaatttgat
     4561 aatattcaaa ttaaatatgg tgattttgtt gcaattgata atctgaattt agatatacat
     4621 gaaggggaat tctttacatt tcttgggcct tcaggatgtg gtaaatcaac tactttgaga
     4681 gcattggtag gttttttaga tccatcatca ggaagtattg aagttaatgg aacagatgtc
     4741 actcatttgg aacctgaaaa gcgtggaatt ggtattgtat ttcaatctta tgcgctattt
     4801 ccaactatga ctgtttttga taatattgca tttggtttaa aagttaagaa ggtagctcca
     4861 gatgttatta aagctaaagt atcagcagtg gcagcaaaaa ttaagatctc tgatcaacag
     4921 ttacagcgta atgtatcaga attatctggg ggtcaacaac aaagggtagc attggctcgt
     4981 gctctggttc ttgaacctaa aattctttgt ctagatgaac cattgtcaaa ccttgacgca
     5041 aaattacgtg tagatttgag aaaagagttg aaaagacttc aaaaagagtt aggtattact
     5101 actttatatg ttactcatga tcaagaggaa gccttgactt tatctgatag aattgcagtc
     5161 tttaacaatg gatacatcga acaggtcggt acaccagtag agatttatca taattctcaa
     5221 actgaatttg tatgtgattt tattggagat attaatgttt tgaccgatga aacagtccac
     5281 gaagtattac tgaaaaatac aagcgttttc ttagaggata aaaaaggtta cattcgatta
     5341 gagaaagttc gattcaatcg tgaaactgaa caagatttta ttctaaaagg gacaattatt
     5401 gatgttgagt tttctggagt tacaattcac tatacaataa aagtttctga aagtcagatt
     5461 cttaatgtaa caagtattga tagtcaggct gctattagat ctgtcggaga aagtgtggaa
     5521 ttatttatca caccatcaga cgttctgcaa ttttaaggag gtgcagtatg cgtcataaat
     5581 taaatttaaa agattggctt attcgtttag ggttaatctg gttcttagta acatttatta
     5641 tttatccaaa ctttgatcta gtagtgaatg tatttgtaaa aggaggagaa ttttcccttg
     5701 atgctgtaca tcgtgttcta aaatctcaga gggcacttca gagtattatg aacagtttta
     5761 agttagcatt ttcactcatt attacagtta atgtcgtagg tattctttgt gttctattta
     5821 cagagtactt tgatattaaa ggtgctaaaa ttttaaaatt aggttatatg acctctttaa
     5881 tttatggagg agtggtttta gcgactggat ataaatttgt ctatggtcct tatggattga
     5941 ttacaaaatt tttacaaaat gttatccctt ctttagactc taactggttt attgggtatg
     6001 gtgcagtctt attcattatg acattttcag gaactgctaa tcatacattg tttttaacaa
     6061 atacaattcg aagcgttgac tatcacacta ttgaggctgc tcgaaatatg ggagcaaaac
     6121 catttactgt tttccgaaaa gtagtgttac caaccttaat tccaactcta tttgcactta
     6181 ctattatggt ttttcttagt ggtttatctg cagtagcagc acccatgatt gttggtggta
     6241 aagaatttca aactataaat ccaatgatta ttacatttgc agggatgggg aattctcgtg
     6301 atttagctgc cttacttgca attattttag gtattgcaac tacaattttg cttactatca
     6361 tgaataagat agaaaaaggt ggaaattata tttctatctc taagactaaa gcgcctctta
     6421 aaaaacaaaa aattgcgtct aagccttgga atatcattgc tcacattgta gcatatggat
     6481 tgttcacagt tttcatgctt ccactaattt ttatagtatt atactcattt acagatccag
     6541 ttgcaattca aacaggtaac ttaacattat caaactttac tttagaaaat tatcgcttat
     6601 tctttagtaa tagtgcggca ttctctccat tcttggtcag ctttatttat tctattattg
     6661 ctgcgacaac agcaacaatt ctcgcagttg tatttgctcg tgttgtcaga aaacataaat
     6721 ctcgttttga tttcttattt gaatatggtg ctctacttcc ttggttacta tcaagtacac
     6781 ttttagcagt aagtttatta tttactttta atcagccaca atttcttgtc ttgaatcaga
     6841 ttttggtagg tagtttggta attctactta ttgcatatat agttgtaaaa atcccatttt
     6901 cttatagaat ggtacgtgct attttattta gtgttgatga tgagatggaa gatgcagcaa
     6961 gaagtatggg tgcttcacct ttttatacta tgatgaaggt tatcattcca tttattttac
     7021 cggttgttct ctctgttatt gctttaaact ttaactcttt attaactgac ttcgacttat
     7081 ctgtattcct ttaccacccc ctagctcaac cattaggtat tacgattcga tctgcaggtg
     7141 atgaaacagc aacatctaat gcacaagctc tggtatttgt ttatacaatt gttctgatga
     7201 ttatttctgg aacggtatta tacttcacac aaagaccggg gcgtaaagta aggaaataat
     7261 catgacagcc actagtcttg ggttatcaaa tattgaaata gttgtcagga ttgttttatc
     7321 agtagtcatt ggtagtataa ttggtttaga gagagggagc aaatcccagc ctgcaggcat
     7381 ccgaacttat agtattgttt gtctagctgc atgtttgatt atgatgacga atgaatacgt
     7441 atcttataaa tttgggacag gagatcctac acgattagga gctcaagtta tatcaggtgt
     7501 gggttttcta ggcgctggaa cgattcttat tacagataaa aagaaaatta caggtctgac
     7561 aactgcagca ggcatttggg cttcggcagg aattggatta gctattggag taggttttta
     7621 tgagggagct cttttagtag ccatttctgt ttggggtgtg atatccatgt tccaaccact
     7681 aaaaaaatat ctacaaaatc gttctaaaat gattgaattg tatatagtag ttaaatctac
     7741 agaagcctat aatcgtgtat tggtttattg tgcagaaaat ggtatcagaa tgaccgattc
     7801 aagaacagcg tttggagatg ttaattctga cagaattgaa tactttgatg ttccagataa
     7861 aaaaatagcg tcatttatta ctctggaatt atcaggtaga tttgaacatc ttcgactgat
     7921 ggaagaaatt gctaatattg taggtgttat ttatgtcgaa gaaattagct gaaatttagt
     7981 aaacaaaggg acagatgttt ttgtcctttt gttttttaga tattttaatc atctaatttt
     8041 tgagtagatt tttgctcag
//
LOCUS       DAVLZG010000073         7990 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLZG010000073 DAVLZG010000000
VERSION     DAVLZG010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.073"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            302..1057
                     /locus_tag="VYO72_001826"
     CDS             302..1057
                     /locus_tag="VYO72_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1708147.1"
                     /translation="MIQLTASTWNINLRSRKGKQIPEMIAQELAQQNSDIICLTEYVK
                     TDNHSQFCSSLQTNGYTIFEDVRTIDFGNEILIAIKSDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKIGGENVFEDFKHRKTQLDKLIFNLPIHENTIILGDFNNG
                     FFKQNDDTHSYQGKPREFYSYPLLKSEMNKAGLTVHTPSEENSWKYCKLDHIIGNIPI
                     SNVCYSWRFLENPDYQNKVGFPDHAILSATISL"
     gene            1097..1315
                     /locus_tag="VYO72_001827"
     CDS             1097..1315
                     /locus_tag="VYO72_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708148.1"
                     /translation="MSDNLKAYLFLLGFVILAGIAIFIFPQGHFFSNSILILGCIPLL
                     ISTYYFAKIKLLGFYELLKELLDKIKGI"
     gene            1321..2643
                     /locus_tag="VYO72_001828"
     CDS             1321..2643
                     /locus_tag="VYO72_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEV1708149.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTSKDGS
                     GYEKIVRSAVLEYEIDRQKGHVLIKALITGDEFSKKVQSLDDVLSDVLELELEEKIIR
                     PSFIEYHFYYIKPKRLVLQSHSQRQEIDSLDIDLGYGVNYNPVKCSHILVSGGTGSGK
                     SVLISVLILEFLKRQSTVYIADPKNSDLGSLSHYFGNKYVATTPNNIARIVRVVVEEM
                     QERYQVMRDNFQYGSNFTNHGFKPVWLIFDEMGAFQATGSDKKSREIITEVMDGIKQI
                     ILLGRQSGIFILVSAQQVNASTTLSTELRDNLGLRIALGANSSEGYHMVFGSATPDKL
                     KPIEEKGSGYLYIQGSGKESAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            2733..3047
                     /locus_tag="VYO72_001829"
     CDS             2733..3047
                     /locus_tag="VYO72_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708150.1"
                     /translation="MKLNDFLKPELLGNKFIAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQVKVNTLSPTASVQEMANNKTCPVTLKDLNVGQYNGNLWFSCSNVILI
                     TK"
     gene            3085..3474
                     /locus_tag="VYO72_001830"
     CDS             3085..3474
                     /locus_tag="VYO72_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708151.1"
                     /translation="MQIFTYNDFLKDKEIVTFEQAEIILDELIKSSNIYDPEFQAYWK
                     ELIEYSAKYAEMRGKWRILTKEEQDTLDDTRTNIHNRIRDNLISIRGLAQINNKDTSW
                     FDKFHNDRKRMGDFANYINYIYAVNSR"
     gene            3493..4263
                     /locus_tag="VYO72_001831"
     CDS             3493..4263
                     /locus_tag="VYO72_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1708152.1"
                     /translation="MAIYYSVSDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDYGS
                     QSFQVISKIIELEKIYPKQIITLFGNHEEWFYDWLILDNPTASAFPETIKSFFSTEEL
                     NYILKTNPNNFETGVRNEIRNNDKYIPFINWFQKRYEDSRYFETENQIFVHAGIDEEA
                     NNLWKDLTSPEIFTNKFPITTGRFYKDIISGHFASWEVAKDKSYLGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVKKSYQYSKNTSLLPKKFDRA"
     gene            4307..5080
                     /locus_tag="VYO72_001832"
     CDS             4307..5080
                     /locus_tag="VYO72_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1708153.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQIAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEYEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTNWATDETLKQLSKPQI"
     gene            5264..6046
                     /locus_tag="VYO72_001833"
     CDS             5264..6046
                     /locus_tag="VYO72_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEV1708154.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDSLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVWINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKYGQYFDNHVKYKKIRLDE"
     gene            6060..6263
                     /locus_tag="VYO72_001834"
     CDS             6060..6263
                     /locus_tag="VYO72_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEV1708155.1"
                     /translation="MIATVTKNDLIALGFFEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLVFDVQNSTLKE"
     gene            6267..7400
                     /locus_tag="VYO72_001835"
     CDS             6267..7400
                     /locus_tag="VYO72_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1708156.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAETRRIVINKKLSQELQDWKKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            7441..7878
                     /locus_tag="VYO72_001836"
     CDS             7441..7878
                     /locus_tag="VYO72_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1708157.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
BASE COUNT         2982 a         1258 c         1306 g         2444 t
ORIGIN      
        1 ctaaaatcaa aatctttttg tcccagactc attctttttt tattaaattt gtacattttg
       61 gaaattaaag tatacttttt tgttgacttt cttcttttaa ttttgtacaa ttaaaatgta
      121 caaaaaaata ctgagaggag gaatagcaat gaactttttt gaccaagaag ccttagatta
      181 cttctatgag gaattggaaa gctactatga tgaagacgaa ctaggagaaa tctttgatgg
      241 attcgaagga tagcaggagg aggtgcctcc tcctgcggac taacttttag gaggaaattt
      301 tatgatacaa cttacagcat ccacttggaa tataaatcta cgttcaagaa aaggaaaaca
      361 aattcctgaa atgattgcgc aggaactagc tcagcaaaat tcagatatta tctgtctgac
      421 agagtatgta aaaacagata atcattctca attctgttct agccttcaaa ctaatggtta
      481 tacaatcttt gaagatgtgc gtactataga ttttggaaat gaaattctta ttgcaataaa
      541 gagtgattta gttaatgatt gccaagtcat tactatcgat aatgatgata ataatccaaa
      601 ctttttacac gttagagtga caattgaagg acaagaatta aacattattg gagttcgtat
      661 caagatagga ggggaaaatg tttttgaaga tttcaaacac agaaaaacac aactagacaa
      721 gctaatcttc aatttaccaa ttcatgaaaa cacaattatt ctaggtgact ttaataatgg
      781 ctttttcaag cagaatgatg atactcattc ctatcaaggt aaacctagag aattttactc
      841 ctatccatta ctaaaatcag aaatgaataa agcaggttta actgtacata ctccgtctga
      901 ggagaactct tggaaatatt gtaaattaga ccatattata ggaaacattc ctatttctaa
      961 tgtgtgttat tcttggagat tcttagaaaa tcctgattat caaaataaag tcggtttccc
     1021 cgaccacgct attttatcgg cgactatatc tttatagttt tccttaaaat aattgcttat
     1081 tagaggaggt aatgaaatga gtgataattt aaaagcatat ctatttcttt taggatttgt
     1141 gatattagct ggcatagcaa tttttatatt ccctcaagga catttctttt cgaattctat
     1201 ccttatcctt gggtgtattc cactacttat ctcaacatat tatttcgcaa aaatcaagct
     1261 cttagggttt tacgaacttt taaaagagct tttagataaa ataaaaggta tctaactaat
     1321 atgtttaaat taagacaaag tgctgattta acaagaaaca atataatttc ctgttataag
     1381 ttaaaaataa tgcactggct gatactaagt atctctgcct gcattctatt ttccactatt
     1441 gttaatatta gggctccaac ttttgttcaa attctcttca tatttttagg tggatttatt
     1501 atctataaaa ttcatctgaa aataaaaatt tttcgatatg acttagagca ttaccttatt
     1561 atacgtgaga gcttacttta tgtactccac acaaacagac tttataccac atctaaagat
     1621 ggttcaggct atgaaaaaat cgttagaagt gcagtattag aatacgagat agatagacaa
     1681 aaaggtcatg ttcttatcaa agctcttata acgggcgatg aatttagtaa aaaagttcaa
     1741 tctcttgatg atgtactttc tgacgtgctt gaactagagc ttgaggaaaa gattattcga
     1801 cctagtttta tagaatatca tttctattac ataaaaccaa aaaggttagt tctacaatct
     1861 cacagccaaa gacaagagat agatagcctt gatatagatt taggatatgg tgtaaattat
     1921 aatcctgtca aatgctcaca tattttagta tcgggtggaa ctggaagtgg gaaatccgtg
     1981 cttatatctg ttttgatttt agaatttcta aaacgtcaat caacagttta tatagctgac
     2041 cctaagaact ctgacctagg tagcttgtct cattactttg gaaataaata cgtagcaacc
     2101 accccaaata atatagctcg cattgtgaga gtcgtagttg aggaaatgca ggaacgatat
     2161 caagtcatgc gtgataactt tcagtatggt tcaaatttta ctaaccatgg atttaagcca
     2221 gtatggctta tatttgatga aatgggagca tttcaagcta caggttcaga taaaaaatca
     2281 agagagatta tcactgaagt tatggatggg attaaacaaa tcattctact tggaagacag
     2341 tcaggcattt ttatcctagt gtctgcccaa caagtaaatg ctagtactac tttaagtact
     2401 gaactcagag ataatttagg attgagaatt gctcttggtg ctaattctag tgaaggctat
     2461 cacatggtct ttggttcggc tactcctgat aagttaaaac ctattgaaga aaaaggttca
     2521 ggctatcttt atatacaagg ctctggtaaa gaatctgccc aatactggga aagcccttat
     2581 cttgatacaa ctcaattcga ttttataaaa gaactacaat tatacgtaac aaagtcaaaa
     2641 taatttcaac agatattttt gcttaaattt aatagatttt cagcaaaaat atctgttcct
     2701 catcgctctg cgatgataga aaagaggtac acatgaagct aaatgatttt ttaaagccag
     2761 aactgcttgg caacaaattt atagcagtaa aaggctatac agaagtatta gacagagaga
     2821 ctaataagcc cgtagcttta cgacttaacg tgtcaattca agatgaggat tctgatttct
     2881 ttatggagat gatacaagtc aaagtaaata cattatcccc tactgcttct gttcaagaaa
     2941 tggcaaataa taaaacctgt cctgttactc taaaagattt aaacgtaggt caatacaatg
     3001 gaaatttatg gttttcttgt tctaatgtaa ttctaattac taaataatgt gttataatta
     3061 tttcaaaaat taaaggagct tactatgcaa atttttactt ataacgattt tctaaaagac
     3121 aaagaaatcg taacttttga acaagctgaa ataattttag atgaacttat aaaatcatca
     3181 aacatttatg accctgaatt tcaagcatac tggaaagaac ttatcgagta cagtgcgaag
     3241 tatgctgaaa tgagaggaaa atggcgaata cttacaaaag aagagcaaga tacacttgat
     3301 gatacaagaa ctaatattca taatagaatt agagataacc ttatatctat tagaggcttg
     3361 gctcaaatca ataacaaaga tacctcttgg ttcgataagt ttcataacga tagaaaacgt
     3421 atgggtgatt ttgctaatta tataaattac atatacgctg taaattcacg ttgattatag
     3481 aaagaatctt atatggcaat ttattattcc gtatctgata tacatgggca ctacaatgag
     3541 tttattaaat ctctcaataa aatagattta tctgataaac aaagtaaact tatcttactt
     3601 ggagactata ttgattacgg ttctcaatct tttcaagtca tttctaaaat aattgaactt
     3661 gaaaagattt atccaaaaca aattattaca ctttttggaa atcatgaaga atggttttat
     3721 gattggttga ttttagataa tcctactgct tctgcgtttc cagaaacaat aaagagtttc
     3781 ttctctacag aggaattgaa ctatatttta aaaacaaatc ctaacaactt tgaaacaggt
     3841 gttagaaacg aaattagaaa taatgataag tatattccat ttataaactg gttccaaaaa
     3901 cgatatgaag atagtcgtta ttttgaaaca gaaaatcaaa tttttgtcca tgctggcatt
     3961 gatgaagaag ctaataatct ttggaaagac ctaacgagtc cagagatatt taccaacaaa
     4021 tttcctatta caactggtag attttataaa gatattatct ctgggcattt tgcttcttgg
     4081 gaagtagcta aagataaaag ttacctaggt aagatttacc atgatagtaa aagtcattac
     4141 tttattgatg gagatgtaaa aaatagcaaa acaatacctg ttatctgcta tgatacagtt
     4201 aaaaaatcct atcaatattc aaaaaacact tctctattgc ctaaaaaatt tgatagagct
     4261 taattctatt cttagactaa tatcaaaaat aaagagggga atatatatga agacattatt
     4321 aattggtgac ttacatttaa aatctcaact aattttaccc attgttgaca aaattatcca
     4381 aacacataac attaagagaa tcatttttct tggtgattat gttgatttac atggtcaaac
     4441 taacaatatc caactttatg ccaaagacct cactttttta tactcttgga aaatagataa
     4501 agagcaaaac ggaatagatg taattaatct tataggtaat catgatgctt attatttact
     4561 gggagaacaa gctcctttct caattcaaaa tttagaagtg tttttcgcag taaaagaatt
     4621 gttgcaggat ttgaaattac aaatagctta tcaactagat gattatttag tcagtcacgc
     4681 tggtttcaat ctgatatttg acccaaaaga atggcatttt aacctttata ccaaagagta
     4741 tgaagaagaa ttagatatcc tagcttatac aataggacca atgcgtggtg ggaaagctct
     4801 tgggggttct cctttatggg cacattttag agaattagaa ttgcttccca accaagactt
     4861 tcctaaacaa attgttggac atacccctaa agaatctatt gatatttcta aaaatgttat
     4921 tggtatagat actttttcat tatatattga caaagataat aaatatcaat ttattggtaa
     4981 cggagatttg ctagtctatg accaaggcca tcttgaaatc atttcaacca actgggctac
     5041 agacgaaaca ttaaaacaat tatctaaacc acaaatttaa ctactacttc tcatcatgtg
     5101 actaagcgaa actgctgact ggaggtcagc aagctggaag cgtgtttagc ggagcgatgc
     5161 ttagaaacac atgatagaag tgtggaggag ctttgctcct cctagtttat ttattatata
     5221 gacaatcttt tggcgaaagc caacctaaaa ggaactattt tttatgacct catataataa
     5281 aaaaatagtc cgcacttctt cctatattga aatttgggaa tatgaaaagc caatattttc
     5341 aaaaggaaaa tctattttag atactaatac tgaaaacaag gaaaaagcaa aacgcagaac
     5401 atttgatgaa ctaacacccc tagaacaaga acaacgtctt gaacgtatga agaagactcg
     5461 cttagaagcc aagtggaact tactccgtct agttgattgt aattttgatg atacaacttc
     5521 ttttcttaca ctgaccacta aggaaaatat cagcgataga aaccacttca aagactcact
     5581 caaaacattt attaaacgct ttaactacca catttttaat accaagaaaa gtaaattaaa
     5641 atatatagca gtattagaga ggcaaaaacg taaagcatgg catagtcata ttttgctatt
     5701 cagtgttccc tatattccac ataagcaatt attagaactt tgggggcatg gtgcagtatg
     5761 gataaataaa gttgacgtcg acagcaaaga aaatcgcggt cgatatgtca caaagtattt
     5821 tgaaaaaggt attggacaag aattgttgga aaacttcgga aagcaagcct atttttcatc
     5881 acgcaacttg aaaaagcctg atgaagataa attttacact tatgaagatt ttaactatga
     5941 tagttcagtc gtgctatatg aaacggaata cactagtaag gtctataaat acggtcagta
     6001 tttcgataat catgtaaagt acaagaaaat aagactagat gaataaagga gtaagtcaca
     6061 tgatagcaac tgttactaag aatgacctaa ttgccctcgg tttctttgag ggaacatcta
     6121 aacgtattat ccgccaaggg aaagagctac tgataacccg aggctttaca gtctatcaga
     6181 acaagcgaat tggtactata cctgctacta ttgctaccga attactcgtt tttgatgttc
     6241 aaaacagtac cctcaaggag taaaatatgg caattagaaa aggtaaagac ggtaattggg
     6301 tagttgatat tagcaacggt tttgacccaa taacactaaa gcaacgtaga cttgtcagaa
     6361 agggctataa gacgaaaaaa gaagctattg aagcagaaca ctacttacga agtgtagagt
     6421 taaaagaacg cttttatgga gctaaaataa ctatccccat actatatgaa ctacttaagg
     6481 aggaagatag tataaatcat cgaaaagcaa gctatatcaa tacacaagat aataattaca
     6541 acaaacacat caaagattat ttttctatgg tcgataatgt cggaaaacta acctatgaag
     6601 acatctacca atttagagaa catcttaggc aaaaagtagc taaaaattct gataaaccgt
     6661 taagcacaaa tactattaac aaaatcatga ttttactcaa aaaaattttt gatgttggtt
     6721 tgcgaaaagg ctattactcc tccaatccag caaaattaat aaaaaagttg ccaattgaaa
     6781 aaacaaaaat gcaattttgg acagtcaaag aatttcagaa gtttttgaca ctatttgaac
     6841 ccgaagaata caatatcaaa ctactcttta ctgttctatt ctttacagga ttaagacttg
     6901 gggaagctct tgccctaaca tggcaagaca tcgacttttc aagtaataca attcatatca
     6961 cgaagtctgt ctatgttaat aaaggagtaa ctcatatcag cacaacaaaa actaaagcag
     7021 aaacaagaag aattgttatc aataaaaaat taagccaaga attacaagat tggaaaaagc
     7081 gacaaaaaca tctattagag caatttacca acaatagcct aacattacaa gtgtttcaaa
     7141 atagtcctat cacaattaca aaaaatgcta ttgaaaagca gtacaagaaa atcattgaac
     7201 gtgatagcac actaaaaaag atacgcatac acgattttag gcactcacac gcttccctgc
     7261 tgattaacca aggggaagat tatctagttg taaaagagcg actaggacat gcttctataa
     7321 caaccacgat tgatacctac tctcacttgt acccaagtaa gcaaaaggat ttagctgata
     7381 aactagatga tttactataa agtaattgag ttttataaat ggaaagttta taattaaatc
     7441 atggatacat cacaagtaat aaaagcacat gaagtagcta aaaaagcaca ctttggacaa
     7501 attgatagag caggaattga ctacattaaa caccctgaaa cagtagctag ttttgtcgca
     7561 actgatgaag agaaagctgt cgcctatcta catgatgtaa ttgaagatac ttcactaacc
     7621 ctactagacc taaaaaagga aggtttttca aaaaacatta tagaagccgt cgatatactc
     7681 acaaagaaaa aaggacaaga ttatcaatct tatctcaatc tagtaaagaa aaatgaactc
     7741 gctagagttg taaagttggc ggatttacgg cataattcag atttaacaag actaccatta
     7801 attactgaaa aagacttaga gagaaataag aaatacagtt ctgctattag atttttaaga
     7861 gcaaagaaaa aaagttagta actaaactat aaaattttat aaagagaaaa caaaagacaa
     7921 ggcttataaa ctttgtcttt attactatac tggcggtcgg tctcgaactg gcacatcctt
     7981 gcagatacta
//
LOCUS       DAVLZG010000074         7788 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLZG010000074 DAVLZG010000000
VERSION     DAVLZG010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.074"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..743)
                     /locus_tag="VYO72_001837"
     CDS             complement(<1..743)
                     /locus_tag="VYO72_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1708158.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMT"
     gene            complement(758..1606)
                     /locus_tag="VYO72_001838"
     CDS             complement(758..1606)
                     /locus_tag="VYO72_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV1708159.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1603..3078)
                     /locus_tag="VYO72_001839"
     CDS             complement(1603..3078)
                     /locus_tag="VYO72_001839"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1708160.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3401..4756)
                     /locus_tag="VYO72_001840"
     CDS             complement(3401..4756)
                     /locus_tag="VYO72_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1708161.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(4766..5083)
                     /locus_tag="VYO72_001841"
     CDS             complement(4766..5083)
                     /locus_tag="VYO72_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1708162.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANLRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5100..5417)
                     /locus_tag="VYO72_001842"
     CDS             complement(5100..5417)
                     /locus_tag="VYO72_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1708163.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5432..6328)
                     /locus_tag="VYO72_001843"
     CDS             complement(5432..6328)
                     /locus_tag="VYO72_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1708164.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6331..7593)
                     /locus_tag="VYO72_001844"
     CDS             complement(6331..7593)
                     /locus_tag="VYO72_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1708165.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDILLYLPFVIAIEKRFKLLED"
BASE COUNT         2685 a         1701 c         1091 g         2311 t
ORIGIN      
        1 gtcattccca tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt
       61 aagacttttg atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact
      121 ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga
      181 gacaactggg aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata
      241 gaaaaaaaca ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta
      301 gaaatcaagc ccaatagaag accacaaatc atatagaatc ctatcttatc aaattgataa
      361 gtttttttaa aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt
      421 tgaacaatgg atactagccg tactgataat tgagataaca aaacttgaaa aataagatga
      481 cctagaaacc ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc
      541 tctttacttt gtgaaaatct tttggttgtt gaaataatcg ccattataaa aacagagaaa
      601 ctagaataaa aagcaatatc actgaccgaa tggtatccaa aactatccat aagtggctta
      661 attataattc caccacccat gcctgatata gaacccaatc cactagctat tataatgatt
      721 agaaaataaa taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac
      781 ctagatggct actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat
      841 tacaataaga acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta
      901 tcccatattt tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg
      961 gattgcgaca ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta
     1021 aaaattcata gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa
     1081 atcttccttg ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag
     1141 gatattcaga ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag
     1201 acattccgct ccaattacag aaagccaatg catcttctaa agcaacatga actactggat
     1261 ggtcttctaa acccactaga ttactattct caccgtaggg atgtttccag caagcgttcg
     1321 gaacttgtaa ccaccacgga gccccagcag gatgaggata tccctccctt tctgcctctg
     1381 gaacgaacaa tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg
     1441 tttctttcac aaattgagca aattcttgat tcgtaactgg agtatccgca atggaaaaat
     1501 cctttacact aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat
     1561 ttgttcccat cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc
     1621 cgttttcgtt agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac
     1681 aacaaaacct tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac
     1741 aataggttgg tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat
     1801 atcaaataac tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa
     1861 gatatattga ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc
     1921 ctcgtactgt ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt
     1981 tcctcctgcc aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat
     2041 tgttccccta ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat
     2101 acttccctga taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg
     2161 atccgaaaca aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa
     2221 aaagcgacta atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct
     2281 tctttgatca tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc
     2341 taatacttcc caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat
     2401 atcaaaatag tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag
     2461 aaaaaaagga accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca
     2521 gtttgttgga tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc
     2581 cattccgtca tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata
     2641 gtcactagca taatcaaatt gacttccata agccttatca tactttctat caacatgtag
     2701 atacccatcg tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg
     2761 catcttacca atacactctg tttgataacc catatcttta aagacttttg gaagagtatt
     2821 agtaaaattc caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa
     2881 gccagtcaat aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc
     2941 aaaattataa cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt
     3001 actattcaag gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg
     3061 ctgttttgtc tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata
     3121 tctaccttta ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg
     3181 ttatgtttta tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat
     3241 tttctagtac tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct
     3301 ttgtctaata acaattttag tggagataag aaatcctaca cctaactcat cttacacgta
     3361 atctatttct attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat
     3421 atgccatttt cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata
     3481 agatgatggc acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta
     3541 cccaagtaac gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta
     3601 ccgttgccat gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa
     3661 ctggtaaacc ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt
     3721 tagcaacttt tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta
     3781 atcctccaaa ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt
     3841 cacctttttg gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga
     3901 tgggagccaa tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga
     3961 tcatcagaat aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct
     4021 tgtaaaccca atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg
     4081 ctactatata catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag
     4141 ggggaactga atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa
     4201 tagaggctaa aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc
     4261 ctggaatcac attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa
     4321 ttccttgtaa gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg
     4381 taactgtact tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg
     4441 tatcaacctt gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa
     4501 caattggtat acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt
     4561 tcgtaatact ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca
     4621 aagcaatgga acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa
     4681 ctaaaaactt ctgattccca actttcattg caattggaga aagtttttct tgcattttat
     4741 ccaacattgt attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca
     4801 cttctttcgc caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca
     4861 tcaagaggct aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag
     4921 ccttatgcgc ctgtaataag gcagcattcg catcagctaa tcttagattg gctttagaga
     4981 aatccccttt ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat
     5041 acataattag ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct
     5101 tagtctaata aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct
     5161 gtcatcggaa taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct
     5221 agtaaatagc gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt
     5281 tcttctgctt caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct
     5341 gccttttgca tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata
     5401 attgttactt tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag
     5461 atactgtatg tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg
     5521 ccagtccccc atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc
     5581 taagtgcaat ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac
     5641 tcaatacaag accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat
     5701 gaaaggctgg aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca
     5761 attgctctgc gacagaaagc tctgccacag gctcattcac tcctgccccg tgcatcttac
     5821 ctgcaataat caaaccagaa aagttttcct tagcagtttg aacagcctta atgatttctc
     5881 gattgctaac tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct
     5941 ctattcgatt caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct
     6001 ctagcatctt tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa
     6061 gctggtgtaa gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct
     6121 caaaaacatc aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag
     6181 aattagttat atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc
     6241 taccttcact tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag
     6301 atggatttgc actaattaaa cgtttcattc tcaatcctcc aataacttaa atcgtttttc
     6361 aatagctatt acaaatggta aataaagtaa gatatccaaa acaatcaata caatttgtag
     6421 taatgaacca gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca
     6481 acctggatct gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag
     6541 taagttaaac attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg
     6601 aacgccaaac attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc
     6661 caaagttttt agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac
     6721 taaacctatg gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt
     6781 aaaaatattt ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc
     6841 taaccataac ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca
     6901 aaaactacta ttaaggaaaa ttaagataag aagaccaata acattatttc ctaaaagtcc
     6961 aagtggacct cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc
     7021 taaagttgca taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact
     7081 aaagctttta gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt
     7141 tataaaccat tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc
     7201 ttttgatgcc atgaaagcgg taggcattcc tgctccagcc tctcctctaa tgaaaggcgt
     7261 aactgtaata aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg
     7321 tctagccata aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact
     7381 atcaacaccc ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc
     7441 tggaatagga aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt
     7501 tagagtaata ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac
     7561 tggaagtaac ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat
     7621 tatcaaaagt tatcaattat ctttattttt tgacgtcaag ttgttatttg attatctttt
     7681 gttatttata ttttacaact ataagaaagc cttgtcaagg atttgtgtaa acatttgatt
     7741 attttttatt atcaatatat aataaaaaga gaccagtaag taatgaaa
//
LOCUS       DAVLZG010000075         7667 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLZG010000075 DAVLZG010000000
VERSION     DAVLZG010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.075"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            133..432
                     /locus_tag="VYO72_001845"
                     /pseudo
     CDS             133..432
                     /locus_tag="VYO72_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            503..2524
                     /locus_tag="VYO72_001846"
     CDS             503..2524
                     /locus_tag="VYO72_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1708166.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2526..3167
                     /locus_tag="VYO72_001847"
     CDS             2526..3167
                     /locus_tag="VYO72_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708167.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3271..4623
                     /locus_tag="VYO72_001848"
     CDS             3271..4623
                     /locus_tag="VYO72_001848"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1708168.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4627..5685
                     /locus_tag="VYO72_001849"
     CDS             4627..5685
                     /locus_tag="VYO72_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1708169.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5695..6894
                     /gene="divIB"
                     /locus_tag="VYO72_001850"
     CDS             5695..6894
                     /gene="divIB"
                     /locus_tag="VYO72_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1708170.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
BASE COUNT         2379 a         1313 c         1671 g         2304 t
ORIGIN      
        1 ttttttcctt gacaacaaat aataaaaaag ttattcttat cacataagaa agcggtttca
       61 ataaaagaga gaggaggatt tattttgttg cattgttgct caaggtgtgc tttttttgaa
      121 agaaaaaata aaatgaaaac gaaaaaacat agattacttg ctctagctct tatttcaaat
      181 tttacattat tgggagctgc atcagctgct gtacaatatc cagatggagg agtatggaca
      241 tatggagaag gttcaggagg tggttaggct ttttcaaatt actatcatgg taaaaaatat
      301 cattattcat ccatcgtgag cagatgggat ggtcattctg ataaaggaga agctcctgct
      361 ggaaaaacct cctatgcatg gatttggact aaatggggag aacaagtagc attttactgt
      421 gattatgact aatcgttcat tgatttaaat cgttcccctt gtaagaaatt acagggggaa
      481 ttttgtttac aaggagtcta ctatgaagaa actattcata ttattatcaa ctttttttct
      541 cagcttcttc cttgcttgga ttattgtctt acgtgcgcca caatatttat atgcaagcta
      601 tgattccgtt tctttacttc gtgtcaaaaa agatactcag gaaccgacgc gtgaggtatt
      661 tgaacaggaa ttggagaatt ttgcaaactc agaacagagt ttaatagcta gaagaattgt
      721 agagccgagt aaggatggga cgactcactt tacttatgca acttatggtc agggaacttt
      781 accaaaagaa ttccaagaag ctagccaaga aagtcgtgaa cgtagtgatc cgctaaatag
      841 ttatctcctt ttgtcaggct ccttgacgaa agaaaagctt gccgataaat taggagattt
      901 gggttataaa gcaagtgctg accgaaagat accgccctat tttcttgctt ttcgaatatt
      961 actaaatccc cttattttaa ttagtttagc aatatttggc ttatctttct ttgctttagt
     1021 gattatcact cggattaagg aaatgagagc agcaggtata aaactctttt ctggtcagac
     1081 tctcttatcc atcatggggc attctttatc tactgatatc aaatggctcc ttctatcagc
     1141 cctcctttcc ttcctaggtg ggggagtcgt tctttttagt caaggtttgt tttatcctat
     1201 cttgttagcc acctatggtt ttgggattag tttctatctg ttgtttttat tggcgatttc
     1261 aattttacta atgcttcttt atctaatgag tttgaattac aaagcattag ttcccgttat
     1321 taaggggaga ttacccctta aacgcctgat gattttaacc ctattgtgtc agttggttgc
     1381 tgtctttaca gtaggatacg ctgttaagac aggtttgacg tcttaccaac gattgaaaga
     1441 acttgaaatt tcaaaacaag catggcagga tagagcagac tattatcaaa tttcttttgg
     1501 cttaggtgat agaggaaaag atacagaaaa tcagagcaag tggtatgcct ttgccaagga
     1561 agcaatcgaa gaagaacaag ctctttatgt aaaggataat ctgctccatt ttgccaatcc
     1621 acaaggaaaa aatgaacagg gagagacact ggatacctat agtccagatg ctaatacgct
     1681 ctatgttagt cccagttatt tggacaagga aaaggtcgtg gtagatgctg agaccaaaca
     1741 gaagttagcc catctccaaa aaggtgagtt tatcctcttg ctcccagaac atttgcgctc
     1801 tcgagaagca gaacttaaga aagtttttga agaaagattg agttattatg gaaaatctgg
     1861 tgaggaggca agtgctcctt tggattatga gatgaaagcg cacgttagtt atctttcaat
     1921 gggagaaaag cggtttgttt ataataacgg tgagaatccc gtatccactc agtatttgac
     1981 tgatccgatt ttagtggtat tcacgccgac ttctacaggt gatagtttta tatccctatc
     2041 tagttggtct atcaatgctg gaaaacaact ctttatcaaa ggatatgaga gtgggctaga
     2101 acttttgaag aaagctggaa tttatgagca agtatcctat cttaaagaag gaagaagtgt
     2161 ttatctaact cgttataatg aagttcaaac tgaaacagca actttaatct taggagctat
     2221 tgtggggata gctagttcct tgttactatt ttattctgtc aatcttctat atttcgagca
     2281 attccgccga gatatcttga ttaaacgaat ttcaggttta cgattttttg aaacacatgc
     2341 tcagtatatg gttagtcaat ttgccagttt tgtatttggt gctagtcttt ttattttaag
     2401 cagtcgagac ttggtgattg gcttgctcac tttattagtc tttctagcta gtgcagttct
     2461 gacgctttac cgtcaagcgc agaaagaatc tcgtgtttct atgacaatta tgaaaggaaa
     2521 ataggatgat tgaactaaag aatatatcta aaaaatttgg aagccgtcag ctattttcag
     2581 atacgaatct tcattttgaa ggtgggaaaa tttatgcctt aatcggtaca agtggctgtg
     2641 gtaagacaac actcttgaat atgattggac gattagagcc atatgacaaa gggcaaatca
     2701 tctatgatgg cacttctctt aaggacatca agccttctgt tttctttaga gattacttag
     2761 gatacttatt tcaagatttt ggcttaattg aaagccaaac cgtcaaagag aatctcaatc
     2821 tgggtttagt tggtaaaaag ttgaaggaaa aagagaaaat ctctttgatg aaacaagctc
     2881 taaaccgtgt aaacctctct tatttggatt tgaagcaacc tatatttgag ttatcaggag
     2941 gagaagcaca acgtgttgca ttagcgaaga taattttaaa ggatccacct ttgatcctcg
     3001 cagatgaacc aaccgcttcc ttagacccca aaaactctga ggaattactt tccatcctag
     3061 aatctttaaa aaatccgaat cgaactatta ttattgcgac ccacaatcct cttatttggg
     3121 aacaagtgga ccaagttatt cgagttaccg atttatcaca tagatgatat ggcaagattc
     3181 agctagaaga aagagtcaca aacacacttt gtggcttttt tatttccata aaaatggtaa
     3241 aatagtagga gtagaaatgg agttcgagac atgaaagtaa tagatcaatt taaaaataag
     3301 aaagtccttg ttttaggttt ggccaagtct ggtgaatctg cagctcgttt gttggacaag
     3361 ctaggtgcca ttgtgacagt aaatgatggg aagcctttcg aggacaatcc agctgcccaa
     3421 agtttgctgg aagaagggat caaggtcatt acaggtggcc atcctttgga actcttggat
     3481 gaagagtttg ctcttatggt gaaaaatcca ggtatcccct acaacaatcc catgattgaa
     3541 aaggctttgg ccaagggaat tccagtcttg actgaggtgg aattggctta tttgatttca
     3601 gaagcaccga ttattggtat cacaggatcg aacggtaaga caaccacaac gactatgatt
     3661 ggggaagttt tgactgctgc tgggcaacat ggtcttttat cagggaatat cggctatcca
     3721 gctagtcagg ttgctcaaat agcgacagac aagaacacgc ttgttatgga actttcttct
     3781 ttccaactca tgggtgttca agaattccat cctgagattg cggttattac taaccttatg
     3841 ccaactcata tcgattatca tggattattt gaggaatatg tagcagccaa gtggaatatc
     3901 cagaacaaga tgacagcagc tgatttcctt gtcttgaact ttaatcaaga cttggcaaaa
     3961 gacttggctt ccaagacaga agccactgtt gtaccatttt caacacttga aaaggttgat
     4021 ggagcttatc tggaagatgg tcaactctac ttccgtggtg aagtagtcat ggcagcgaat
     4081 gaaatcggtg ttccaggtag ccacaatgtg gaaaatgccc ttgcgactat tgctgtagcc
     4141 aagcttcgtg atgtggacaa tcaaaccatc aaggaaactc tttcagcctt cggtggtgtc
     4201 aaacaccgtc tccagtttgt ggatgacatc aagggtgtta aattctataa cgacagtaaa
     4261 tcaactaata tcttggctac tcaaaaagcc ttatcaggat ttgacaacag caaggtcgtc
     4321 ttgattgcag gtggtttgga ccgtggcaat gagtttgacg aattggtgcc agacattact
     4381 ggactcaaga agatggtcat cctgggtcaa tctgcagaac gtgtcaaacg ggcagcagac
     4441 aaggctggtg tcgcttatgt ggaggcgaca gatattgcag atgcgacccg taaggcctat
     4501 gaacttgcga ctcaaggaga tgtggttctt cttagtcctg ccaatgccag ctgggatatg
     4561 tatgctaact ttgaagtacg tggcgacctc tttatcgaca cagtagcgga gttaaaagaa
     4621 taaaatatga aaaaaattgt ctttacaggt ggggggacgg ttggacacgt taccctcaat
     4681 cttttgttaa tgcccaagtt catcgaagat ggttgggaag tccactatat cggggacaag
     4741 cgtggtatcg aacaccaaga aatccttaag tcaggtttgg atgtcacctt ccattctatt
     4801 gcgactggga aattgcgtcg ctatttctct tggcaaaata tgctggacgt cttcaaagtt
     4861 ggctggggaa tcgtccaatc gctctttatc atgttgcgac ttcgtccaca gacccttttt
     4921 tcaaagggag gctttgtctc agtaccgcct gttatcgctg cgcgtgtgtc aggagtgcct
     4981 gtctttattc acgaatctga cctgtctatg ggcttggcca ataaaatcgc ctataaattt
     5041 gcgactaaga tgtattcaac ctttgaacaa gcttcgagtt tggctaaggt cgagcatgtg
     5101 ggagcggtga ccaaggtttc ggatcaaaaa aatccagaac cagatgaatt ggtggatatt
     5161 caaagccact ttaatcataa attgccgact gtattgtttg ttggcggttc tgcaggtgct
     5221 cgtgtcttta accaattggt gacagaccat aagaaagaac taacagagcg ctacaatatt
     5281 atcaatctaa ctggagattc tagcctgaat gagttgagcc aaaatctttt tcgtgttgac
     5341 tatgtgaccg atctctatca acccttgatg gaattggctg atattgttgt gacacgtggt
     5401 ggtgccaata cgatttttga gctcttggcg atagcaaaat tgcatgtcat tgtgccactt
     5461 ggtcgtgaag ctagtcgtgg tgaccagatt gaaaatgcag cttactttgt taagaaaggc
     5521 tatgcagaag accttcaaga aagcgatttg accttggata gtttggaaga gaagctttct
     5581 cacttactaa gtcacaagga agattaccaa gctaagatga aagcttctaa ggaattgaaa
     5641 tctctagcag atttttatca attgttgaaa aaagatttat cataaggaaa gtaaatgtca
     5701 aaagataaga aaaatgagga caaagaaatc ctcgaagaat tgaaagagtt atcagaatgg
     5761 cagaaacgaa accaagaata tctaaaaaag aaggctgaag aagaagcggc tctagctgag
     5821 gagaaggaaa aggaaagaca agctcggatg ggagaagaat ctgagaagtc agaggacaaa
     5881 caggaccagg agagtgaaac agaccaggaa gattcagaat cagctaagga agagtctgaa
     5941 gaaaaagtag catcctcaga ggctgacaaa gagaaagaag agaaagaaga atcagagtct
     6001 aaagagaagg aggaacagga taaaaagctt gctaaaaagg ctacaaagga aaaaccagcc
     6061 aaagcaaaga ttcctggtat ccatatcttg cgagccttca cgattttatt tccaagtctg
     6121 cttttattga ttgtctctgc ctacttgctc agtccttatg cgaccatgaa agatattcgt
     6181 gttgagggaa cggtgcaaac tacagctgat gatattcgac aggcttcagg cattcaggat
     6241 tcggattata cgattaacct tctgctagac aaggcaaaat atgaaaagca gattaagtct
     6301 aactattggg ttgaatcagc tcaacttgtc tatcaatttc caactaagtt cactattaag
     6361 gtcaaggaat atgatattgt ggcctactat atttctggtg aaaatcatta tcctattctt
     6421 tccagtggtc agcttgagac tagttctgtg agtctgaaca gtttaccaga aacttattta
     6481 tcagttctct ttaatgatag tgaacaaatc aaggtttttg tctcagaact tgctcaaatt
     6541 agcccagaac tcaaggcggc tatccaaaag gtggaattag ccccaagcaa ggtgacatcc
     6601 gatttaattc gattgaccat gaatgattcg gacgaagtct tggttcctct atctgaaatg
     6661 agtaagaaac tgccatatta cagtaagatt aagccacaat tgtcagaacc gagtgtggtc
     6721 gacatggaag ctggaattta cagttacact gtggcggata aattaattat ggaggctgag
     6781 gaaaaagcca aacaagaggc caaggaagct gagaaaaaac aagaagaaga acagaaaaaa
     6841 caagaggaag agagcaatcg aaatcaaaca aatcagcgtt catcgcgtcg ctaggtttac
     6901 cttttctctt atagttcttt agtgaccatg tttttacgtt taatatttga catttgtttt
     6961 tctttatgtt acatctgcaa tgtaatcgat tacaaaataa tttttgatga agaaggtaac
     7021 acatatgtca gatgaagtat tcttatttga agaaattgaa gaaatcgtag cccctacaga
     7081 tggtgaattt ttgggggaag ttttacttgg aactggggta gttctcttaa ttggagtagc
     7141 ctgttgttaa aaagataggg agtgataatc atgcaagata actttttatt tgaggaaatt
     7201 gaagaaattt cagtaccagt tagtgatttt tcagctggac ttgcaacagg tatcggattt
     7261 ggtttagcaa tccttgctct tgctggttgt tgaagtttgt tcatttacta acatcaagct
     7321 ttttcaattt cattttagac agtcatttga attttccgta ttagtcttgc agcaagagat
     7381 taatagaatt agtcattatt ttattgattg cggactgagg gactagagta tgttttactt
     7441 agcccctctt ttatttatta aaggttaggt ttgttatgag aattgttgat aagattaaga
     7501 tattacctac tccttatgag ggacagtatc atctatatat accatccagt aagaaacatg
     7561 tattagttgg gaaacaggaa aaaaatggtt agagcaacta ataggtcaag aatttaccat
     7621 atcggactta ttagtgttag tagggaagaa atattattta agatttt
//
LOCUS       DAVLZG010000076         7341 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLZG010000076 DAVLZG010000000
VERSION     DAVLZG010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.076"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            607..777
                     /locus_tag="VYO72_001851"
     CDS             607..777
                     /locus_tag="VYO72_001851"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1708171.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            1389..1673
                     /locus_tag="VYO72_001852"
     CDS             1389..1673
                     /locus_tag="VYO72_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708172.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1666..1914
                     /locus_tag="VYO72_001853"
     CDS             1666..1914
                     /locus_tag="VYO72_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708173.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLHATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            2010..2228
                     /locus_tag="VYO72_001854"
     CDS             2010..2228
                     /locus_tag="VYO72_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708174.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LESFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2596..4920)
                     /gene="pflB"
                     /locus_tag="VYO72_001855"
     CDS             complement(2596..4920)
                     /gene="pflB"
                     /locus_tag="VYO72_001855"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1708175.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5268..6329
                     /gene="dinB"
                     /locus_tag="VYO72_001856"
     CDS             5268..6329
                     /gene="dinB"
                     /locus_tag="VYO72_001856"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1708176.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILCAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(6476..7321)
                     /locus_tag="VYO72_001857"
     CDS             complement(6476..7321)
                     /locus_tag="VYO72_001857"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1708177.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         2403 a         1373 c         1357 g         2208 t
ORIGIN      
        1 tagtagatat ctcgtattta gacaatatga aaacaagacg acttccatat aggaaaccgc
       61 cttctctcta tgttgagtga tttatattaa aataactttt cttctagctg cattttatta
      121 ttataaaaac attcatcata accctgaact taaataacga tttttattca agatacatac
      181 tcctagaata aactttatat gaaattctca tttttgtttt tacaattctc cttagttaaa
      241 tcttgtttaa tatatgtttt acatatagta tttagcgcca catagtactg aactctctcc
      301 aaaaacggtt attcctcttt gaatagggcg ttatcacaag aaaagcatct ccacgtttca
      361 acttcatatg gctcaaaaac aatcaattga tgctaaaacc tgtacctaga tgtttcggtt
      421 cataaaacca tgaaactgta aaagtggatg aaattgatag cgatagtcaa atcaagaggc
      481 atcataactc taaaaagtca caatatataa gttcatcctc ggaaaaatat cattctaatt
      541 gttgaaatgc ctacatgaaa agaaacgtca aatactcatg aaacaacgaa tacaggtatc
      601 aaaactatga caaaacaagt ccctaaattt actaaagaca ctgctcaact ttacacctgt
      661 aaatggttgt tgtataataa agttacaaag atgtacgacc acactgttgt aaatcatagt
      721 gttcgcgaat atattactga tagcatttct acaaatacaa ttgaagagac tggatagact
      781 ttaaacgaaa tatgtcagtg ttttggcatt cctagccttc atatcattta aagaattcta
      841 tagacaaaat ttttcccaat acagacactc gtaacaactg cttcattttt ctaccaacat
      901 atttaggaac aggataagat acaagaggat taatccatag atcagttcta taccaatcta
      961 agacaaataa gctaaaaaaa cgattgataa taagcaaata gattccaaat tttctctatc
     1021 tgctcatttt aataaacaat actagtgtaa ctatccttcc agtcagaagc ttgtcaaatc
     1081 acaccgaaaa ttcttctaaa atttatctcg ttaggcaatc aagcaaaaac tcgacgatag
     1141 tacaaacatt atcatacaga attgacttcc taaattatat actttagtaa ggttttcgta
     1201 taagaaaaaa gattcatttt acatttctaa acattctttt ctaagatgaa aaacagaatt
     1261 tttcgattgt gatttaaagc aacaagaaga ttttcagtat catcctatag atacgagcta
     1321 attaagaaaa actacatttt cgaatataaa ctacaataat ataaactaaa ttttatagga
     1381 ggaagacaat ggattggtac gattatatga tacaggcatc caaacaatca caattcaacg
     1441 caagccattg gtttcgctat ttgcgaaaag ttatttttga agactattct tatttaacaa
     1501 accaagatgt agaaaagttg ctagactcca aagaactaac ccgttttcaa aaaattagct
     1561 tgaagtatgc ctttcaagag catactccaa ctcataaata tgtgatttca ttaaataaac
     1621 ctgctaagtt aaccaatgtt caaaaattga tggagaaata caaacatgga taaaatgaaa
     1681 ccggtcttcc aagccctaaa taaggaatta attcaggaaa atctgacttt aacaattatc
     1741 tgtgtcgatg gttatgtctt agaatatcat ggtttacatg ccacacaaga tgttgatgct
     1801 ttttatgacc aaaatcagaa aatcaatgaa attattgctc gtgtaggaaa acagtttaat
     1861 cttaacatcc acgaagagtt atggctcaac aatcatgttg caaagcaaat atgaacaaac
     1921 aacctccctt aagtttatgc gaatccttgt actcatttga gaatctgacc gttttagtag
     1981 tccctattga gtatgtgtta ggaatgaaga tgatgagtat cagagagcag gatttgcaag
     2041 atattggtgc aattattaaa tacaaaaact ttcattcacc attcgatacc tttaaatatt
     2101 taaaagacat gggatttgat actattgacc tctctgttct attagaaagt tttagttatg
     2161 cttatggtat ggattggtta gaaaaatttt ttaaagaaaa tcaagataaa cttcgcgaat
     2221 tttattaaca gtatcaaaca agatgattgt caattagcca gtcgtcttgt tttttatgat
     2281 gaaatgaaat aaaatctgaa caaatcgctt agagaattcc agtcaatttc tagcgctgtt
     2341 tgagacgttt cagtggacta tagtaaaatg aaataagaat aggacaaatc gatcaggaca
     2401 gtcaaatcga tttctaagaa tgttttagaa ataaaggtgt actattctag tttcaatcta
     2461 ttatatttca gattcggtcc actattcctt cccaaaaaca ttgcatattg cgccgaagga
     2521 attgctcata ctatcccaag cacaaaaccc tcagtcgttt gaccgagggt tcctttttat
     2581 tattcaagaa cttgattagc tcaatgcatc caaggcgtca tccattgaaa gaacttcgtg
     2641 gaagacacgt tgtgtcaatt cagttttttg ttctggagtg aggtatttag tgtttacaca
     2701 gtatccagag atacgtacga taacgtcttc gcctgacatg attttttcgt aaacatcgtt
     2761 caagtccata acgttcaagt taacgtgttg tccaccgttt tcgaagtaac catcaaggat
     2821 tgttaccaag ttatcaactt gttcatcacg agtcttacca agagcgcgag gtgatacttg
     2881 tgtagtcaat gagataccgt cagctgcata actaaagtca aggctagaaa gtgagttcaa
     2941 gttttgcaac caaccacctt tagctttgtt agatgggtta gcacctggtg agaagaattc
     3001 aagtttagac aagttcacag aaccatcttc gttgaggtat acacctttgt gaactggtga
     3061 gttaccagtt tgtttagagt aagcaacgtt agatgtgatt gtcaaaagtg atactgtagc
     3121 ttctgcgtct ttgtatagtt tgtggctacg tagacgagtt gtgtaagctt cgatcaacca
     3181 ttctgccaat tcgtttgaac gtgggtcatc ttcaccccag cgtgggtagt caccgattgt
     3241 ttcgtaatcg tagatgtagc catcttcgtc acggattggt ttaactgtag cgtatttgat
     3301 agctgacaat gtatcaacag tgttagcaaa tccacagata ccgaatccca tgttggcacg
     3361 ttgtttagtt ggcaagaagg ccatttgaac agcttcgtag ttgtacctat cagtcatgta
     3421 gtggatgatg ttcaaggcat ctacgtaagt gtcagtcaac cagtcaagag atttttcaaa
     3481 gttcgcttta actgattcga attcaagaac ttcgtcacgg attggttcga tatcaaatac
     3541 tttgtagtct ttgtgaacat cgtcgtaacc accattcaaa ccagtaagaa gggctttaag
     3601 aacgtttaca cgagcaccga agtactggat gttgtggcgt tgttcttcat tttctggatc
     3661 aagtggagac acacagcatg agatacagct catttcacca tatccgtctt tagccattgt
     3721 tgttacacct tcgtattgga tagaagagtg tttgtggctc atgtgcatac agtagcgacg
     3781 gaagttgtat ggcaatttgt cagtccaaag aactgtcaag tttggttctg gtgagttacc
     3841 gatgttgtca agagtgttca agaaacggta gtccatctta gtaacacggt gacgaccgtc
     3901 gttacccata ccagccatag aagttgtgat aaaggttggg tcacctgagt acaattggtc
     3961 ataagctttg gtacgagcaa atttaactgt acgaagtttc ataacgaaat catcaacgaa
     4021 ttcttggatt tctgattcag taaatgtacc acgagcaagg tcacgttctg caaagatgtc
     4081 caatacgatt ggtacacgac ctagagatgt agcagcaccg ttaatcacac ggcagacagc
     4141 catgaaagca atgttaaccc attggattgc ttctttcacg ttcatcgctg gtttgcgaac
     4201 atcaaccccg taaaggtcac ccaggcgaac aacttgttgc aatgcttggt attgaaggtt
     4261 tacttcttca cgaagacgga ttgtttcttc atcgatttct ttgattgcat tccagtcatt
     4321 tactttttct tgcatcaagt agtctgcacc gtaaagagca agacgtgcgt aaacaccgat
     4381 gatacgtccg cgtgagtatg catctggaag accagttaca gtgtgtgcgt gacgagcgcg
     4441 acgaatattt gaagtgtagg cacggaaaat accgtcgtta actgttgtta catatttagt
     4501 gaagatttcg tgaacagctg ggtctggttc gtatccattt tctttcaaag tagtttcagc
     4561 catacggata ccaccttttg gcatgaagtt caatttgaag agttcatcgt tttggatacc
     4621 gaagataact tcattttctt tgtcgataaa tccagcaggg atatcagcga tagatgttgg
     4681 acgagtgtcc attgggaaac gagtttcttc gtagtgtgct ttagtttctt ctacaatttt
     4741 cttgatgtga agtgaacgct ctgttggtcc tgcaaggaag ctttcgtctc catcataagg
     4801 tgtgtagtta gcttgtacaa atcgtgatac acttgctttt tctttccaat ctacgccttt
     4861 gaagccttcc caagctttgt caaaaatatc ttgtgcttca acaactgtct taacaaccat
     4921 attaatgtcc tcttttttct agtaacagtc atctgttaca ttcataagac aagtatacca
     4981 tatagtaacc gatttcaaca agtgaaaatt ccctattttt acactttctt ttctaaaaca
     5041 gtctatattt tatttcaaac tgtattatat ttttgaaaaa ataaagtcct tttttctttt
     5101 tttcagaaaa aagggtataa taaaagaaaa taagcagtaa cactcaatgg aaatcgaaaa
     5161 gcaaactagg aagctagccg cagattgctc aaaacactgt tttgaggttg cagatagagc
     5221 tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt gctaggcatg ttgatttttc
     5281 ctttgttaaa tgatttgtca agaaaaatca tccatattga catggatgcc ttttttgctg
     5341 cagtggaaat cagggataat cctaaactca gaggaaaacc tgtcattatt ggaagcgacc
     5401 ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag ttatgaggca agagcttttg
     5461 gtgtccattc tgccatgagt tccaaggaag cttatgaacg ttgtccccag gctgtcttta
     5521 tctcagggaa ttatgagaaa tacaagtctg tgggactcca gattcgagct atttttaagc
     5581 gctatacaga tttgattgaa cccatgagca ttgacgaagc ctatttggat gtgacagaaa
     5641 ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct cattcaaaaa gatatctggc
     5701 aagaactcca tctaactgct tctgccggta tttcctataa caagttctta gctaaaatgg
     5761 cgagtgatta tcaaaaacct catggtttga cagtgattct acctgaacag gctgaggatt
     5821 ttctcaaaca aatggatatt tccaaatttc atggagtagg aaaaaagaca gtagaacgtc
     5881 ttcatcaaat gggcgttttt actggtgctg atttacttga agttcctgag gtgaccctaa
     5941 tagaccgttt tggtagacta ggctatgatc tgtatcgaaa ggctcgtggc attcacaact
     6001 ctccagtcaa atccaatcgc atccgtaaat caatcggcaa ggagaaaacc tacgggaaga
     6061 ttctctgtgc tgaggaagat atcaaaaaag agctgactct tctatcagaa aaagtcgctc
     6121 tcaatctaca tcaacaagaa aaagctggaa aaattgtcat tttgaaaatc cgctacgagg
     6181 acttttcaac tcttaccaaa cgaaaaagta ttgctcaaaa aacacaagat gctagtcaga
     6241 taagccaaat agccctgcaa ctctatgaag aattaagtga gaaagaaaga ggtgtccgcc
     6301 tattggggat taccatgact ggattttaaa gctcaatgaa aatcaaagag caaactagga
     6361 ggctagccgc aggctgctca aaacactgtt ttgaggttgc agataaagct gacgcggttt
     6421 gaagagattt tctaagagta taaaaccttg aagagttgcc ccttcaaggt ttttcttata
     6481 caaataaacg gacaaaactg taaagtagca aaacactacc aagcacgata cggtatttac
     6541 caaaaagggt gaagtcgtgt tttttcacat agctggtcaa gaagcgaata gccaccatgc
     6601 tgaccgcaaa agctactccc atcgcgacca agagcaaaaa caattgccca aagctcaaga
     6661 gttctccggc tttcacaaat ttgaaaatct ttaaggcact agctccaaac ataacaggaa
     6721 tcccaagata gaaggtaaat tctgtcacaa ctgaacgact ggttccattt aacaaaccac
     6781 cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag agcaagaact tggaagagtc
     6841 cgatatagaa agcggtcgta taaggaagct tgtccaactc tgttacactt ggctcgatag
     6901 cacgcgcttt attgcgcttt tccaaataga tgaaggcaac cccgtagata atcaacatga
     6961 gagcaactga aaccatgtta tggaagtggg tatcaaacca atcatcaaat ttaaagacac
     7021 caagtaaagg taaagtagca atcaagacct tcaaccatag tctccaagtc ttacgaactt
     7081 cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt aaaataaatc accataactg
     7141 ctaaaatagc accaagctga atcacgacat taaacatgga cataaaggct tcattttgat
     7201 tttggtattg gatgaattcc tctgctaaaa tcaagtgacc tgtactggaa atcggcaacc
     7261 attccgtaat tccttcaaca atcccgaaga agatagattt taaaatttca ataagataca
     7321 tagattactc cctatattat a
//
LOCUS       DAVLZG010000077         7285 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLZG010000077 DAVLZG010000000
VERSION     DAVLZG010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7285
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.077"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            1..589
                     /locus_tag="VYO72_001858"
                     /pseudo
     CDS             1..589
                     /locus_tag="VYO72_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            756..956
                     /locus_tag="VYO72_001859"
     CDS             756..956
                     /locus_tag="VYO72_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708178.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            998..1402
                     /locus_tag="VYO72_001860"
     CDS             998..1402
                     /locus_tag="VYO72_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708179.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1633..2340
                     /gene="ccdA2"
                     /locus_tag="VYO72_001861"
     CDS             1633..2340
                     /gene="ccdA2"
                     /locus_tag="VYO72_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1708180.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDFNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2351..2908
                     /gene="sdbB"
                     /locus_tag="VYO72_001862"
     CDS             2351..2908
                     /gene="sdbB"
                     /locus_tag="VYO72_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1708181.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3282..4673
                     /locus_tag="VYO72_001863"
     CDS             3282..4673
                     /locus_tag="VYO72_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1708182.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4816..5733
                     /gene="adcAII"
                     /locus_tag="VYO72_001864"
     CDS             4816..5733
                     /gene="adcAII"
                     /locus_tag="VYO72_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1708183.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5741..>7285
                     /gene="phtB"
                     /locus_tag="VYO72_001865"
     CDS             5741..>7285
                     /gene="phtB"
                     /locus_tag="VYO72_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1708184.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDISSDKVKLVEDILAFLAPIRHP
                     ERLGKPN"
BASE COUNT         2266 a         1340 c         1527 g         2152 t
ORIGIN      
        1 aggtagtata acagaagcat cacacgtttt ccaaatctca cgtaatacca tttatggctg
       61 gttaaagcta aaagagaaaa caggagagtt aaaccaccaa gtaaaaggaa caaaaccaag
      121 aaaagttgat agagatagac ttaaaaacta tcttactgac aatccagacg cttatttgac
      181 tgaaatagct tctgaatttg gctgtcatcc aactaccatc cactatgcgt tcaaagctat
      241 gggctacact cgaaaaaaag aaccacacct actatgaaca agacccagaa aagtagcctt
      301 atttcttaag aattttaata gtttaaagca cctagcacct gtttagattg atgaaacagg
      361 attcgatact tatttttatc gagaatatgg tcgctcatta aaaggtcagt taagaagagg
      421 caaagtatct ggaagaagat atcagaggat ttctttggtt gcaggtctaa caaatggtga
      481 attaatcgct ccaatgactt acgaagagat gatgacgagc gacttttttg aagtatggtt
      541 tcagaagttt ttcttaccaa cattaaccac accatcggtt attatagtaa aatgaaataa
      601 gaataggaca aatcgatcag gacagtaaaa tcgaattcta acaatgtttt agaagtccat
      661 atgtactatt ctagtttcaa tataccataa ctgttcctag tcaacctgca agccctgtcc
      721 cagctccaag ctcagctccg actcaagatc ctagagtggt agcaagcgct tcggctagct
      781 caacgagcac acaagctcaa gagcaagttg acaagtctga acttcgtgcc ttgagtcaag
      841 agttagacca acgcttgaaa gctttggcaa cagtatctga tccgaaaatc gatgcaacca
      901 aggctgtcct cctagatgct caaaaagctc cggaagatag tgccttgaca gagtaaggtc
      961 tgcatactgc agtagagtct gtgaaggctg ggctgccttg gactctctca aagatgtgaa
     1021 agcaaatgct agcgacagca agcctgcaca ggacaagaag gatgcaaaac aaggaacgga
     1081 agatagtaag gattcagata agatgactga aacaaactca gttccggcag gagtgattgt
     1141 ggtcagtcta cttgccctcc taggcgtgat tgccttctgg ctgattcgcc gtaagaaaga
     1201 gtcagaaatc cagcaattaa gcacggaatt gatcaaggtt ctaggacagc tagatgcaga
     1261 aaaagcggat aaaaaagtcc ttgccaaagc ccaaaacctt ctccaagaaa cccttgattt
     1321 cgtgaaagaa gaaaatggct cagcagagac agaaactaaa ctagtagagg agcttaaagc
     1381 aatccttgac aaactcaagt aaaacatgat ttatgaaatg tcagacctaa aagacatttt
     1441 cgttcacaaa agcagcgatg agtaatcctt gtcgttgctt tttggctatt ttgggggata
     1501 agatccgcct tgactagcaa aagaaaagat tggtccaata gtgcccgata cgattttgcg
     1561 tagcagaaag cttacaaata aaattgaata tagtaaaata ggattagaat tattaagaaa
     1621 gttggttctt tattggaaac gatagtattt ttaatctctg tttttctagc aggtgtttta
     1681 tccttttttt ctccttgtat ttttcctctt ctgccagtct atgctgggat tttattggat
     1741 gatcaagaaa gtgcaaaaag cttttctttg tttgggagaa aggttctctg gtcaggcttg
     1801 attcgaacac tttgctttat cgctggtatc tctctcattt tctttattct aggctttggt
     1861 gctggttact ttggtcatat tctctatgca aattggtttc gatatgtcat gggagctatt
     1921 attatcattt tgggtcttca ccagatggaa atttttcatt tgaagaaatt agaagttcaa
     1981 aaaagtttta cctttaaaaa atcagatttt aatcgttatt ggtcagcttt tttacttggt
     2041 attaccttta gctttggttg gacaccttgt attggtccag ttttaagttc tgttttagca
     2101 cttgcggctt ctggaggcaa tggtgcttgg caaggagcga tttatactct catttacact
     2161 ctgggcatgg cccttccttt cttggtcttg gcactagctt caggtctagt catgccatat
     2221 tttagtaaaa tcaagcgtca tatgatgcta ctaaagaaaa ttggtggttt cctcattgtt
     2281 ttaatgggaa ttttgttact attaggacaa gtaaatgttc tagctggaat ttttgaataa
     2341 aggaggacaa atgaaaaaag taatgtttgc tggcttaagt ctcttgtcat tagttgtatt
     2401 gatggcctgt ggtgaggaag aaactaaaaa gactcaagca gcacaacagc caaaacaaca
     2461 aacgactgta caacaaattt ctgttggaaa agatgctcca gactttacat tgcaatccat
     2521 ggatggcaaa gaagttaagt tatctgattt taagggtaaa aaggtttact tgaagttttg
     2581 ggcttcatgg tgtggtccat gcaagaaaag tatgccagag ttgatggaac tagcggcgaa
     2641 accagatcgt gatttcgaaa ttcttactgt cattgcacca ggaattcaag gtgaaaaaac
     2701 tgttgagcaa ttcccacaat ggttccagga acaaggatat aaggatatcc cagttcttta
     2761 tgataccaaa gcaaccacct tccaagctta tcaaattcga agcattccta cagaatattt
     2821 aattgatagc caaggaaaga ttggaaagat tcaatttggt gctatcagta atgcggatgc
     2881 agaagcagca tttaaagaaa tgaactagaa tcgataaaat ctgattacaa gatgtagtca
     2941 gattttggta acttctaaaa ctaacttcca gtttcccaca acctagcttt tagtatgaga
     3001 aaaacgcgtg acatcagtgg aaatccgtct tagactaact tccactggtt ttctttttct
     3061 tgatatataa gggttcaaaa gcgaaaagac tcagaaaaag tgcacgacaa atagccctaa
     3121 aacagagtcg tcttagagta acttccagtt ttgggagaga gatggaagtt actttgagaa
     3181 gttacggtag tcagattttt ttagaaaaac attttataaa tattcacata tctcctatat
     3241 ttatggtaaa atagaattat cagtttattt tggagtcaaa gatgaatata tttagaacaa
     3301 agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg gatttgattt
     3361 tgctgggtat cggagccatg gtagggacag gcgtctttac aatcacaggt actgcagctg
     3421 caacacttgc tggcccagcc ctagtgattt caatcgttat ttctgccttg tgtgtgggat
     3481 tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga ggtgcctata
     3541 gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg ttaaccatga
     3601 tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat tttaaaggct
     3661 tgctctctca atacgggata gcctttcctc aggctttaaa tggtaccttt aatcctcaag
     3721 cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact tcgcttgttt
     3781 tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg aaattttccg
     3841 ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat tggagcaatt
     3901 ttgctcctta cggttttgga caaatctatg gagctagtac tggtattatg gctggtgcat
     3961 ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta gatgaagtca
     4021 agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc gtaaccattc
     4081 tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat ttaaatgtcg
     4141 atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc aactatgtgt
     4201 cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat gccctatcgc
     4261 gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag gaactgacga
     4321 agactagcaa ggtaccaaag aatgctacta tcttgacagg tctagcttca gcagtagcag
     4381 caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc ttagcctact
     4441 tgatcatgtt ggcttatggt ctgattcgct tacggaaaga aaaaggaatg cccaaagctg
     4501 gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc atttgtttat
     4561 ccttcatgtt acagtataat atgaatacct ggattgcttt cctagttgcg ttgttagtag
     4621 gaagtattat ttacttcact tatggctata agcattctac catagaagaa taaagtgaaa
     4681 gtctattgag ttgttgacac tcagcagatt tttatatgtg aaagaaattt caaatttttt
     4741 ctaaaaatat cttgacagat taaattttca ggagtagaat atttactagt taattaaatg
     4801 gttaaggagt tgttcatgaa gaaacaaaat ttatttttag tcctgttaag tgtctttctt
     4861 ttgtgcttgg gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat gaaaattgtg
     4921 accagttttt atcctatcta cgctatggtt aaggaagtat ctggtgactt gaatgatgtt
     4981 cggatgattc agtcaagtag tggtattcac tcctttgaac cttcggcaaa tgatatcgca
     5041 gccatctatg atgcagatgt ctttgtttac cattctcata cactcgaatc ttgggcagga
     5101 agtctggatc ccaatctaaa aaaatccaaa gtgaaggtct tagaggcttc tgagggaatg
     5161 accttggaac gtgtccctgg actagaggat gtggaagcag gggatggagt tgatgaaaaa
     5221 acgctctatg accctcacac atggctagat cctgaaaaag ctggagaaga agcccaaatt
     5281 atcgctgata aactttcaga ggtggatagt gagcataaag agacttatca aaaaaatgcg
     5341 caagccttta tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa atttgaaaaa
     5401 gcgactcaga aaacatttgt aacacaacat acagcctttt cttatctagc gaagagattt
     5461 gggcttaatc aacttggtat tgcaggcatc tctcctgaac aagaaccaag tccacgacaa
     5521 ttagcagaaa ttcaggaatt tgttaaaacc tataaggtta aaacgatttt tacagaaagt
     5581 aatgcttctt caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg tcttaaaact
     5641 ctgaatcctt tagaggcaga cccacaaaat gacaagacct atttagaaaa tctggaagaa
     5701 aatatgagtg ttctagcaga agaattaaag tgaggaaaga atgaaaatca ataaaaaata
     5761 tctagcaggt tcggtggcag ttcttgccct aagtgtttgt tcctatgagc ttggacgtta
     5821 ccaagctggt caggataaga aagagtctaa tcgagttgct tatatagatg gtgatcaggc
     5881 tggtcaaaag gcagaaaact tgacaccaga tgaagtcagt aagagggagg ggatcaacgc
     5941 cgaacaaatc gtcatcaaga ttacggatca aggttatgtg acctctcatg gagaccatta
     6001 tcattactat aatggcaagg tcccttatga tgccatcatc agtgaagagc tcctcatgaa
     6061 agatccgaat tatcagttga aggattcaga cattgtcaat gaaatcaagg gtggttatgt
     6121 ccttaaggta aacggtaaat actatgttta ccttaaggat gcagctcatg cggataatat
     6181 tcggacaaaa gaagagatta aacgtcagaa gcaggaacgc agtcataatc ataactcaag
     6241 agcagataat gctgttgctg cagccagagc ccaaggacgt tatacaacgg atgatgggta
     6301 tatcttcaat gcatctgata tcattgaaga tacgggcgat gcctatatcg ttcctcacgg
     6361 cgaccattac cattacattc ctaagaatga gttatcagct agcgagttag ctgctgccca
     6421 agcctattgg aatgggaagc agggatctcg tccttcttca agttctagtt ataatgcaaa
     6481 tacagctcaa ccaagattgt cagagaacca caatctgact gtcactccaa cttatcatca
     6541 aaatcaaggg gaaaacattt caagcctttt acgtgaattg tatgctaaac ccttatcaga
     6601 acgccatgtg gaatctgatg gccttatttt cgacccagcg caaatcacaa gtcgaaccgc
     6661 cagaggtgta gctgtccctc atggtaacca ttaccacttt atcccttatg aacaaatgtc
     6721 tgaattggaa aaacgaattg ctcgtattat tccccttcgt tatcgttcaa accattgggt
     6781 accagattca agaccagaac aaccaagtcc acaatcgact ccggaaccta gtccaagtct
     6841 gcaacctgca ccaaatcctc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6901 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6961 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     7021 gcaggaaagt ttatctcata agctaggagc taagaaaact gacctcccat ctagtgatag
     7081 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     7141 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatat
     7201 ctcaagtgat aaagtcaagt tagtggaaga tattcttgcc ttcttagctc cgattcgtca
     7261 tccagaacgt ttaggaaaac caaat
//
LOCUS       DAVLZG010000078         6903 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLZG010000078 DAVLZG010000000
VERSION     DAVLZG010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.078"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            1..494
                     /locus_tag="VYO72_001866"
                     /pseudo
     CDS             1..494
                     /locus_tag="VYO72_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            555..1517
                     /locus_tag="VYO72_001867"
     CDS             555..1517
                     /locus_tag="VYO72_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1708185.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1694..2701
                     /gene="gap"
                     /locus_tag="VYO72_001868"
     CDS             1694..2701
                     /gene="gap"
                     /locus_tag="VYO72_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1708186.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2769..3605)
                     /locus_tag="VYO72_001869"
     CDS             complement(2769..3605)
                     /locus_tag="VYO72_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1708187.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3731..5926
                     /locus_tag="VYO72_001870"
     CDS             3731..5926
                     /locus_tag="VYO72_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1708188.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5979..6131
                     /gene="rpmG"
                     /locus_tag="VYO72_001871"
     CDS             5979..6131
                     /gene="rpmG"
                     /locus_tag="VYO72_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1708189.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6141..6317
                     /gene="secE"
                     /locus_tag="VYO72_001872"
     CDS             6141..6317
                     /gene="secE"
                     /locus_tag="VYO72_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1708190.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6372..>6903
                     /gene="nusG"
                     /locus_tag="VYO72_001873"
     CDS             6372..>6903
                     /gene="nusG"
                     /locus_tag="VYO72_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1708191.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2144 a         1208 c         1491 g         2060 t
ORIGIN      
        1 tatttcttaa gaattttaat agtttaaagc acctagcacc tgtttagatt gacgaaacag
       61 gattcgatac ttatttttat cgagaatatg gtcgctcatt aaaaggtcag ttaataagag
      121 gcaaagtatc tggaagaaga tatcagagga tttctttggt tgcaggtcta acaaatggtg
      181 aattaatcgc tccaatgact tacgaagaga cgatgacgag cgactttttt gaagcttggt
      241 ttcagaattt tctcttacca acattaacca caccatcggt tattattatg gataatgtaa
      301 gattccatag aatggggaag ctagaacttt tatgcgaaga gtttgggcat aaactgttac
      361 ctcttcctcc ctactcgcct gagtacaatc ctattgagaa aacatgggct catatcaaaa
      421 agcacctcaa aaaggtatta ccaagttgca atacctttta cgaggctctt ttgtcttgtt
      481 cttgtttcaa ttgactatag ttcacggata cagttgggaa agaagctatt aattatttgg
      541 agagtccttt tgggatgaac atgtcaaata ttactataga tgggcaagaa atggatctga
      601 gtcaaacgat gccttcttat gctcaagtag tgagtcttta tgaggataca agcatctctg
      661 ttagtagtaa tgagacggac aaagtgttgg ctggatccct ctatactgat acaaatgaac
      721 agggattaat gattccaagc agtttactaa aaaattggaa tgaacagaca ggaaaaaatt
      781 tgacagctaa tgatcttatt ggcaaatcag tctcagccag cattgtagaa agtgctgccg
      841 aagctagtaa gattgctcaa tttcaaacga agattgtacg tgtaatcaat gatgaagatg
      901 acatggagga cagcaacagt ttcatgctgt ctcatcaaat ggaaacgatt ttgaaagagg
      961 ctggatttac gaaagctgta tcttatttta tcttggaact caaagatcca tcacagacaa
     1021 aagtagtaac agaagaatta cagaaaaata agaagtatac tgtgctttct caacagagag
     1081 ttcttgatat tgtgattacc tttattcgtg ttattcaggg attattgatt gtgctttcat
     1141 cacaagctat tgtggtagca gcggttatga ttggtatcat tatttacatc aatatcatgc
     1201 aacgttccaa ggaaataggt gtcatgaaag cagttggtta tcagaatcgt ggtgtcaaag
     1261 gaatttttat ttacgaggct atctggattg taggcatcgc cttgctgctg gcatttttgg
     1321 ttgcacaagg ggtgggaagt ttggcgaatg cgattgtaag tcacttttac ccatccatca
     1381 ctaaggtttt tgaattaaat cttttatctg ttttaggaac tctagttttc gctctattac
     1441 ttggttatgt ctcagcctac ttcccggcgc gtaagattag taaaatggat cctgtagaat
     1501 cgttacgcta tgaataataa gggattcctt gatttacagt cttaaaaaga aactcacata
     1561 gaaaaacaat ggccatactt gcaattcaac tcaaatagtt gtataatagg tttgttgaaa
     1621 ggtgatttgt agtgattcaa gttactcttt tcacaataaa aatttcatga ttttcataag
     1681 gaggaaatca ctaatggtag ttaaagttgg tattaacggt ttcggacgta tcggtcgtct
     1741 tgctttccgt cgtatccaaa acgtagaagg tgttgaagtt acacgcatca acgaccttac
     1801 agatccagtt atgcttgcac acttgttgaa atacgacaca actcaaggtc gtttcgacgg
     1861 tactgttgaa gttaaagaag gtggatttga agttaacggt aaattcatca aagtttctgc
     1921 tgaacgtgat ccagaacaaa tcgactgggc tactgacggt gtagaaatcg ttcttgaagc
     1981 tactggtttc tttgctaaga aagaagcagc tgaaaaacac cttaaaggtg gagctaaaaa
     2041 agttgttatc actgctcctg gtggaaacga cgttaaaaca gttgtattca acactaacca
     2101 cgacgttctt gacggtactg aaacagttat ctcaggtgct tcatgtacta caaactgctt
     2161 ggctccaatg gctaaagctc ttcaagacaa ctttggtgtt gttgaaggat tgatgactac
     2221 tatccacgct tacactggtg accaaatgat ccttgacgga ccacaccgtg gtggtgacct
     2281 tcgccgtgct cgcgctggtg ctgcaaacat cgttcctaac tcaactggtg ctgcaaaagc
     2341 tatcggtctt gtaatcccag aattgaatgg taaacttgat ggatctgcac aacgcgttcc
     2401 aactccaact ggatcagtta ctgaattggt agcagttctt gaaaagaacg ttactgttga
     2461 tgaagtgaac gcagctatga aagcagcttc aaacgaatca tacggttaca cagaagatcc
     2521 aatcgtatct tcagatatcg taggtatgtc ttacggttca ttatttgacg caactcaaac
     2581 taaagttctt gacgttgacg gtaaacaatt ggttaaagtt gtatcatggt acgacaacga
     2641 aatgtcatac actgcacaac ttgttcgtac tcttgaatac ttcgcaaaga ttgctaaata
     2701 attcttgagt tgatagaaag caaggctttg tggtcttgct tttttatatg gaaaaatgga
     2761 tgacacgatc atccattctt ttttaattct ttttcaaatg tatttgaaag ggtagtgaaa
     2821 gttagcctct ctaaagtaag tgggtgggta aaggaaagtc ggaaggcatg aagcataagc
     2881 cggcttgtct ttgatttact attatagaga gggtctccca ggataggaag attatgatgc
     2941 aaaaggtgca cacgaatctg atgggttcgc cctgtcttta gcttgcaatg agccaaggaa
     3001 gtcttgtttg agaattgctt taatctgctt acatgcgttt cagcatattg cccatttttt
     3061 gcatcaacta ttctttttct acgatcatgg cgatcacgtc caattttgtc tctgaaaaca
     3121 agttcttttc tgttgatatt tccatcaact agagcccaat attctctaga aatctctttt
     3181 ttctccaata agcgattgag aatgggcagg ataaaaggat ttttggcaaa gagaactaag
     3241 ccactggttt ccatgtccag acgatgaacg acatagcagg tttggccaac ataggtactg
     3301 acatggttaa gaagggcaat ttcgtttggt tgattaccat gcgttttcat cccctctggt
     3361 ttgtttacaa taatcaagtg ttgatcttga taaacttcct gcactaagtc tgggttgccc
     3421 caagggatcg tcttttgggg ataatcttcc tcgtcaaaag tcaactggca aacatctcca
     3481 ggatttacga tttcgttcca gcggacttct tcttgattta tcaaaatatg tttcttgatt
     3541 ctcaaaaaat gacggatttt tctagggatg aggagttgtt cctcaagtaa ttgctttacc
     3601 gtcatttgag gtagagaggc gggtaatgta aatgtgaatt gcatacagat attgtaacaa
     3661 aaaaagccct atttggatag gaaatagcta aattcttgtc ttcctatgat gaagatgata
     3721 aaataaacgc atgaaattag ataaattatt tgagaaattt ctttctcttt ttaaaaaaga
     3781 aacaagtgaa ctagaggact ctgattctac tatcttacgt cgctctcgta gtgatcgaaa
     3841 aaaattagcc caagtaggtc cgattcgaaa attctggcgt cgttatcatc taacaaagat
     3901 tatccttata ctaggtttga gtgcaggctt gctagttgga atctatttgt ttgctgtagc
     3961 caagtcgacc aatgtcaatg atttgcaaaa tgccttgaaa actcggactc ttatttttga
     4021 ccgtgaagaa aaagaggctg gtgccttgtc tggtcaaaag ggaacctatg ttgagctgac
     4081 tgacatcagt aaaaacttgc agaatgctgt tattgcgaca gaagaccgtt ctttctataa
     4141 aaatgacggg attaactatg gccgtttctt cttggctatt gtcactgctg gacgttcagg
     4201 tggtggctct accattaccc aacagctggc taaaaacgcc tatttatcgc aggatcaaac
     4261 tgttgagaga aaagcgaaag aatttttcct tgccttagaa ttaagcaaaa aatatagtaa
     4321 ggagcaaatt ctaaccatgt accttaacaa cgcttatttt ggaaatggtg tgtggggtgt
     4381 agaagatgcg agtaagaaat actttggagt ttctgcatca gaagtgagtc tggatcaagc
     4441 tgcgactctg gcagggatgc tcaaggggcc ggaactgtat aatcccttga attccgtaga
     4501 agattctact aatcggcgcg atactgtctt gcagaatatg gttgcagcag gatatattga
     4561 taaaaaccaa gaaaccgaag ctgctgaagt tgatatgact tcgcaattgc acgataagta
     4621 tgaaggaaaa atctcagatt accgttaccc ctcttatttt gatgcggtgg ttaatgaagc
     4681 tgtttccaag tataatctaa cagaggaaga gattgtcaat aatggctacc gcatttacac
     4741 agagctggac caaaactacc aagcaaatat gcagattgtt tatgaaaaca catcgctatt
     4801 tccgagggca gaggatggaa cgtttgctca atcaggaagt gtagctctcg aaccgaaaac
     4861 agggggagtt cgtggagttg tcggtcaagt tgctgacaat gataaaactg gattccggaa
     4921 tttcaactat gcaacccaat caaagcgtag tcctggttct acaattaagc ctttagttgt
     4981 ttatacgcca gcagttgaag caggctgggc tttgaataag cagttggata accataccat
     5041 gcagtatgac agctataagg ttgataacta tgcagggatc aaaacgagtc gagaagttcc
     5101 tatgtatcaa gccttggcag aatcgcttaa tctacctgct gttgccactg ttaatgattt
     5161 gggtgtcgac aaggcttttg aggcaggcga aaaattcgga ctcaacatgg aaaaggtcga
     5221 ccgtgttctt ggtgtcgcct tgggaagcgg tgttgaaacc aaccctcttc aaatggctca
     5281 agcatacgct gcctttgcaa atgaaggttt aatgcctgaa gctcatttta ttagtagaat
     5341 tgaaaatgct agtggacaag ttattgcgaa tcataaaaat tcacaaaaac gggtgattga
     5401 taagtctgta gctgacaaga tgaccagtat gatgttgggg actttcacca acggtaccgg
     5461 tattagttca tcgcctgcag actatgtcat ggcagggaaa actggaacaa ctgaagcagt
     5521 tttcaatccg gagtacacaa gtgaccagtg ggtaattggt tatactccgg atgtagtgat
     5581 tagccactgg cttggctttc cgaccactga tgaaaatcac tatctagctg gctctacttc
     5641 aaacggtgca gctcatgtct ttagaaacat tgccaatacc attttacctt atacgccagg
     5701 aagtaccttt acggttgaaa atgcttataa gcaaaatgga attgcaccag ccaatacaaa
     5761 aagacaagta caaaccaatg ataatagcca gacagatgat aatttgtctg atattcgagg
     5821 gcgtgcgcaa agtctagtag atgaggctag ccgggctatc tcagatgcga agattaagga
     5881 aaaggctcaa acaatatggg attcgatagt caatctattt cgctaagatg cttgtcaaag
     5941 cctagctttc ttgttataat ggataagatg gaggcgttat ggcactaaaa aaagcaagcc
     6001 tagcttgtgc ggtttgtggt tcgagaaact attcaatcaa gatcagcgga aaccccaagc
     6061 ctacacgact agaagtaaat aaattttgta agcattgtgg caagtacact acacacagag
     6121 aaacgagata ggagagagcg atgcgtttta ttggagatat ttttagactt cttaaagaca
     6181 caacatggcc aactcgcaag gaaagctgga gagattttcg ttctatcatg gaatacacag
     6241 ctttctttgt agtaattatt tacatttttg accagttgat tgtttcaggt ttgattcgat
     6301 ttattaacat tttttagaag attagtggag ttaattacac tagaaatctt ctatttatga
     6361 aaggaaatat catggatagt tttgataaag gatggtttgt tttacaaact tattctggtt
     6421 atgaaaataa ggtgaaagaa aatctattac aacgtgcaca aacctacaat atgttggata
     6481 atattctacg cgttgaaatt ccaacacaaa cagtgcaagt tgaaaaaaat ggaaagagaa
     6541 aagaagtaga agaaaatcgc tttccaggtt atgttcttgt agaaatggtc atgacagatg
     6601 aagcttggtt tgttgttcga aacacaccaa atgttacagg atttgtcgga tcacacggga
     6661 acagatcaaa accaactcca ttattggaac aagaaattcg tgacattttg gtatctatgg
     6721 gacaaactgt tcaagaattt gatttcgatg ttgagattgg tcaaactgta cgtattattg
     6781 atggtgcttt tgcagactac actggtaaga ttacagaaat tgataataac aaagtgaaaa
     6841 tgattatctc tatgtttggt aatgacacag ttgcagaagt aaacctaaac caaatcgcag
     6901 aat
//
LOCUS       DAVLZG010000079         6757 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLZG010000079 DAVLZG010000000
VERSION     DAVLZG010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.079"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            6..3291
                     /locus_tag="VYO72_001874"
                     /pseudo
     CDS             6..3291
                     /locus_tag="VYO72_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            3535..3636
                     /locus_tag="VYO72_001875"
                     /pseudo
     CDS             3535..3636
                     /locus_tag="VYO72_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3877..4347)
                     /locus_tag="VYO72_001876"
     CDS             complement(3877..4347)
                     /locus_tag="VYO72_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1708192.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4364..6637)
                     /locus_tag="VYO72_001877"
     CDS             complement(4364..6637)
                     /locus_tag="VYO72_001877"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1708193.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2056 a         1147 c         1472 g         2082 t
ORIGIN      
        1 aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct ttttcaaaac
       61 cttgcattga agctgagaat atgattgcta catcaactgt ggctactgcc tttatggcgc
      121 gtcgtgcttt agagcaggct gtccattgga tatatagtca cgattcatat ttagaagctc
      181 cctatcgtgc tactctatct tctttagtat gggatgatga ttttagggat atcgtagatt
      241 ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct gctcatggtg
      301 gtgaaattaa ggaacgagaa gcgattttag ctttgcatca tttgtatcag tttgttaatt
      361 ttatcgatta ttgttacagc aatgagtttg tggagcgtta ttttgatgag aagtgcttac
      421 cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag ttacaagaca
      481 gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta gaagttcaag
      541 agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct ttccatattg
      601 atcaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc cgtttagcag
      661 gatggatatt tgaagaaaac tgtcgtgttg agatagccgt tgatggtctc aagcacggtt
      721 caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg
      781 tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc aaagaatatg
      841 ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca aatgggttga
      901 agcactatat acttgatggt ccgaaccgcc gccagattgc aggcttttac tctcaagaag
      961 aattgcaatt agtgatggat agacgtcatc ttcaaaaacc gcttgaggat atttctagta
     1021 aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca agcgtttgtg
     1081 aagctttctc tgatcatcgt agacaggcac ttttggttat ggcaactggg gcggggaaaa
     1141 ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta aaaaacgttc
     1201 tcttcttagc cgatagaact tccttggtta agcaagccta tgattcgttt agaaaattac
     1261 tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa tcaagtcgta
     1321 tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa gaagtaaatc
     1381 aacgcccttt tactgttggg cattttgacc ttatcataat tgacgaatct caccgttcta
     1441 tttatcagaa atacaagtcc atttttgatt attttgatgc aaggattgta ggcttaacag
     1501 ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg gagaatgggg
     1561 ttccaacata tgcatatgat ttggaagagg ctgttaaaga cggatattta gtagcctatc
     1621 attctatcga aaccaaactg aagctaccta cggatggtct acattatgat gatttgtccg
     1681 aagaagaaaa ggaacatttt gatagcaaat ttgaagacga tagctgtgaa aaagatattg
     1741 atgggagtgt gtttaattcc tttattttca ataaaagtac agtagaaatt gttttaaatg
     1801 aactcatgac aagaggaatt cagacagcct cgggtgatga aattggtaaa actattattt
     1861 ttgctaaaaa tcatgaccat gcggaatata tcagaggtat ttttaacaac cgctatcctg
     1921 aaaaagggag cgactatgct caggtgattg attatagtat taagcattat cagaccttga
     1981 ttgatgattt taaaattaag gagaagtatc ctcaaattgc gatttctgtc gatatgttag
     2041 atacaggtat tgatgtacca gaggttgtta atttagtctt cttcaagaaa gtacgctcta
     2101 aaactaagtt ttggcagatg attggtcgag gaacccgtct atgtaaagat ttatttggac
     2161 ctgagcagga taagaaaaac ttcttggtat ttgattatgg ggacaatttt gattattttc
     2221 gtgcagatcc aagagatgga gagggtcgtc acattgtttc gctgactcag cgtttattta
     2281 atatcaaagt ggacttgatt cgagaacttc agggactcca ataccaagaa gatcagtttg
     2341 cgagagcata ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag agcttaaatg
     2401 agttggactt cagggttcgt atggttttag atacagttta tagctatagg aaattggaaa
     2461 gttggcagaa tctaactgct gttacaagtg aaaccattca aaaaaatctc tctccgcttt
     2521 tatttgatga agataaagaa gatgagatgg cgaggagatt tgatttgtgg ttgcttcata
     2581 ttcagttggg gcaactgaca gctaaatctt ccactgttca tatttcccaa gtgatgaaga
     2641 cggctagagc tctttctgct attggcaata tcccgcaggt ttttgagcag gctgaaatta
     2701 tcagggaagt acaggagcct gaattttgga aagaagttaa cttgtctgat ttggaaaaaa
     2761 ttcgtcttgc tattcgagat ttattacagt ttttggataa aacagaccgt aaaccctact
     2821 atgttaactt tgaagatcgt atactctcca ctgttcacga gaccacagca tttttgcagg
     2881 tcaacgatct tcggtcttac aatgaaaaag ttgacatctg atgatatgct tgcacttgaa
     2941 aaattgcttt gggaaaaatt aggtagtaaa gcagactacc aaagtcatta tgaaaataag
     3001 gcaattccga gattggttcg tgagattatt ggcttagata gagagtctgc caatcgtatt
     3061 ttttctaaat ttttgtcgga tgagaatctt aatgccaggc agatttcatt tgtaaaattg
     3121 attgtagact acattgtaga aaatggtttt ttagagacga aagtgttaac gcaagagccg
     3181 tttaaatctt atggttctgt tcaactactc ttccaacacc aactaccagt acttcgtaat
     3241 attgttcaaa tcattgaact tatcaataat cgagctggag aagcggctta aattctaaag
     3301 tgattgccat gctgagactc atttaaaatt aaaaagagta gaaatttatg atatatatga
     3361 gaagttttat taggaagaat gtcatcgttt ttctagaata cagtatcagt tgttaagtgg
     3421 ctgataaatt tcaaagtaga tacttgtacc acgatgtttg ttgatcgagt tattaacaaa
     3481 agagctactt tgattttaaa gaaatagaaa acaaaaagcc gagcaagaat tcaattgcag
     3541 gagaaaatga aataatactc aatgaaaatc aaagagcaaa ctaggaaact agctgcaggc
     3601 tgctcaaaac actgttttga ggttgtagat aagactgacg aagtcagctc aaaacatggt
     3661 tttgaggttg tagatgaaac tgacgaagtc agtaaccata cctacggcaa ggcgacgttg
     3721 acgcggattg aagagatttt cgaagagtat aaatcttcct aggataaagc aaaacgcata
     3781 gtatcaaggg ttttcaacac ttgatactat gcgttttctg atgttaaaga ctttctacca
     3841 gtttttttaa gcataattgt tagttgtagt catttattat tcttcaaaga aaaatggtgg
     3901 ggcgaatttt ttcagttctt caaagcactt ttgagcagta tctgcatctt cacagatgat
     3961 aagacagaca tcattaccac aaagggtagc gatagcgtca gggaagctca aagtatcaat
     4021 gatagaacca aaggattgag ccagtccagg aagggttttt agtaggactt ggtgttgaac
     4081 tgggcgcatc cagacaaggg cgtcttccat gtagagttcg agacgttttt cccattttga
     4141 gatggaacca ttgttaagaa cataataagc gctatcttct tcgcggactt ttgataggtt
     4201 catatttttg atgtcgcgtg agagggttgc ctgggttact tgaatgtcgt tcttagcaag
     4261 aagggcttgc aactcagcct gtgtatgaat cttgtttttt gtgataagag cgcgtataag
     4321 ttggtggcgg tgttctgatt tattcataat aatgtaactc cttttagcaa ggtaaggtaa
     4381 gcatggactg agcgaggtcg acagtcaagt ggtagtctgt attgtcacgg atggtgattt
     4441 caaagtcagt agtatagagg actaaacgga gagtgtctcc ttcttttagc ttgtaaatag
     4501 ttggctgcag ttcaaattga acgtccatcc attcatctgc agtaatatcc tctactaaca
     4561 gtaaatcatt tctattttgt aaattaaggt aaccttttgt cacgactcgt tgtgcctctg
     4621 gtctaaatgg caattcacag agattttcca acatgtgata gcgaccgttg tcaatggttc
     4681 tagcacttaa aatagctgga taaggttgta ggtatttctt ttgcccaaat tctagcagtt
     4741 gggcagataa gagccccttg tttgtactgg atttgatacg aagattgagc tgagcgcgac
     4801 catttaggtg gagatcttta gtcacaggaa ggttaatagt aatctgattg gctttccctt
     4861 gatagagctc tgtattgaag gtttggtatg tcttaccata gcgctcaaaa tccttatctg
     4921 ggtactggtt ttgaatagct tgctcttctt gaccaagtga gaaggtttca cagttttctt
     4981 gcccaccgaa gttatcaagt gataaccaag tctgtggagc tgtattgtcc tgccagataa
     5041 cagtaggaag ttgaaagtct gtttcctgtc ctagtaattt cttggtcaat aaggcattta
     5101 tggactcacg gaagtcaatt gattgccaat tgttcatgta aacatgagca ccattatgga
     5161 aaaagagatg cttgtgtata tgagtaggaa gagcatggaa catctggtaa acatgaagtg
     5221 gtttgacatt ccaatcctga gaaccatgag taaagacaac ctctgccttt actttatggg
     5281 cattgagcag ataattgcgg tcatgccaaa actgattgta gtccccagtt tttcgatcta
     5341 gctgagcttt cactttttct aagtcagctt ggtgagcttc attgccacgg atatagtcgc
     5401 cagctaagag attacgagaa taggttaact cagcaaggga gtcaaagtcc tcacctggat
     5461 aaccacctgg gctagtcacc agaccgtttt cacggtagta gttgtaccat gatgaaattc
     5521 ctgcctcggc aatgataact tctaaaccat cgactcctgt agtcgcaaga ccattggaca
     5581 tggtacctag ataggaaagt cctgttgtag caacttttcc gtttgaccaa tcagccttga
     5641 cttgacgctg gcgcgtgtga tcagtaaagg cacggcaacg gccgttaagc caatcgatga
     5701 catttttata agcctcgatt tgctggtagt ctccattagt catgaaacct gtcgagtctt
     5761 tggtaccaac acctgagaca tagagattgg caaagcctct cggaaggaag tagtcgttta
     5821 gtgtatagct agagttgatg tgagttagct tttcctcagc ctctgctata agctcagctt
     5881 taccttgggg ttggacgaga tttagttgag gtttctctag ctcaatcttg tgaggaagct
     5941 taacctcaag ctcgccctcc atcttgtaga gagccttgtc actagccttg tcattggttc
     6001 cctgatgata agggctggct gtcatgatgg cagggatttt tccatcaaaa cgagggcgaa
     6061 taatgctaac ctttactagg tctggtagcc ctttttggtc agtatcgaca cgagactcaa
     6121 cgtaaacgac ttcacgaatg acatcctggc tagaaaaagt agccaaactc ttgccgttaa
     6181 agtagtggta gtcattatcc tccggaataa gaccatcact aacaagttgg tcgataagag
     6241 tatttccttt tttggtgcga gtattgagta actgatagag attttcaatc aagtcaccat
     6301 atataatggg aaatccagtt tctttacgaa aaacgtcact atcttcgaag tcaaccaaat
     6361 aagaaaagcc taaaagttga aaagcaacag tataaaaaat atctgctgtc agttcatctt
     6421 ctgattgaaa aaatgtcagc aggtctgttt ttttatcagc tgctaggata gaaagtgggt
     6481 agttggtgtc ttgataagtg aaaaagaaac gacgtaaaaa ggtttcaagt gagtctttgt
     6541 gattggctgt attttgtaaa tcaaagccac atttttttag ttcagataag acattttctt
     6601 ttggaaaatt gatataacta tattgattaa aacgcataga acctccatat agaatgacag
     6661 ttaaggttat tatatcaaaa aaaaagcaga aagggaattg ttaacttcaa aaggaaataa
     6721 tccaataaaa atgaataaag tactaaattc aatatag
//
LOCUS       DAVLZG010000080         6732 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLZG010000080 DAVLZG010000000
VERSION     DAVLZG010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.080"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(94..679)
                     /locus_tag="VYO72_001878"
                     /pseudo
     CDS             complement(94..679)
                     /locus_tag="VYO72_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(655..831)
                     /locus_tag="VYO72_001879"
     CDS             complement(655..831)
                     /locus_tag="VYO72_001879"
                     /inference="COORDINATES: protein motif:HMM:NF015247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708194.1"
                     /translation="MQRNSGGKPTTELPSFIIRCLPVHLTYDNNYFNDTYQGIPIGGY
                     TQIVEKCWIMKILM"
     gene            complement(797..1267)
                     /locus_tag="VYO72_001880"
     CDS             complement(797..1267)
                     /locus_tag="VYO72_001880"
                     /inference="COORDINATES: protein motif:HMM:NF013739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HEV1708195.1"
                     /translation="MYDYLVVGAVFAHEAALEGKKVKVIEKRNHIAGNIYTREEEGIQ
                     VHQYGAHIFHTSDKEIWDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNKLWGVV
                     TPAEVQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGQTNY"
     gene            complement(1330..2181)
                     /gene="rfbD"
                     /locus_tag="VYO72_001881"
     CDS             complement(1330..2181)
                     /gene="rfbD"
                     /locus_tag="VYO72_001881"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1708196.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            complement(2247..3296)
                     /gene="rfbB"
                     /locus_tag="VYO72_001882"
     CDS             complement(2247..3296)
                     /gene="rfbB"
                     /locus_tag="VYO72_001882"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1708197.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(3309..3902)
                     /locus_tag="VYO72_001883"
     CDS             complement(3309..3902)
                     /locus_tag="VYO72_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1708198.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            complement(3903..4772)
                     /gene="rfbA"
                     /locus_tag="VYO72_001884"
     CDS             complement(3903..4772)
                     /gene="rfbA"
                     /locus_tag="VYO72_001884"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1708199.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            complement(4799..5899)
                     /gene="glf"
                     /locus_tag="VYO72_001885"
     CDS             complement(4799..5899)
                     /gene="glf"
                     /locus_tag="VYO72_001885"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEV1708200.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            complement(5902..>6732)
                     /locus_tag="VYO72_001886"
     CDS             complement(5902..>6732)
                     /locus_tag="VYO72_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HEV1708201.1"
                     /translation="IKIRRHLKPIFVLLGSVIAIEIYTMLDTTMIGAMVGTTEVGYYT
                     NSMKLVKLLITVITAIGGVLLPRLSDYYSKGEFEKLNHIVDKVFRIMLFLFLPAQVAL
                     ILVAPVIMPILFGDSFIPAVLTLQLTSLLICTLGFSNLFGTQILLTFGDERKLLISTI
                     LGALSNIALNLILIPVMAQNGAALASVISETIVTLTAYYYAKKRVTIRFDLGFYLPTV
                     VSTIIMGGAIYVVMQLYIGDIEKMLFSTLLGGVVFLLINVFMKNPIIYEFTGIIKRKR
                     "
BASE COUNT         1971 a         1482 c         1119 g         2160 t
ORIGIN      
        1 catatagtca aggaattttt aatactattt ctaaataata actggtagtc agttttactt
       61 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgcaa cctcaaaaca
      121 gtgttttgag caacctgcgg ctagcttcct agtttgctct ttaattttca ttgagtatga
      181 atctaactca tttctcacgc actgcaaagc tgctccaatt acttggtgca tatcgtaata
      241 acgatagtgt cctaagcggc caccaaagat aacattccct tgctcatcag caagtttttt
      301 atatgattta tacaaatgat tattacgatc attattaact ggataataag gctcatcacc
      361 tttttcccat gttttagaat gttctattag taatgatagt ctttgcttga ctcccaaact
      421 caaaatgttt gtgttcaata atgcgagtat atggggtttc tgcatccgta tagttcacaa
      481 ctgcatttcc ttggtaattt tccatatcca aggtctcatt ttcaaaacga agactacggt
      541 actctagttc gcccaactta tagtcaaaga attcatcaat cataccagta aagacaatct
      601 taggaaaatc tttcagatat tgctctttgt tcacaaagaa atcaacattt gtttctacat
      661 caatattttc atgatccaac atttttcaac tatttgagtg tatccaccaa ttggaatccc
      721 ttgataggta tcgttaaaat agttgttatc ataggtcagg tgtactggta aacagcgaat
      781 aataaaggat ggaagttcag tagttggttt gcccccactg tttctctgta tagtctttga
      841 ttaatttttc gtagatgtct gtacctacaa gagaaatcgc ctgttcttcc aaattttcag
      901 gagttttacc atttaaaata gcacgttgtt catcaatctt agcctgtact tctgctggcg
      961 ttacaactcc ccagagttta ttgaaggtat tcatattaaa aggaaggtta taaatctcac
     1021 ccttatagtt tgcaacagga gaattggtat aacggttaaa ctctgcaaac tgatttacat
     1081 aatcccagat ctccttatca gaagtatgga agatatgagc accatattga tgaacttgaa
     1141 ttccttcctc ttcacgagta tagatattac ccgcgatatg atttcgtttt tcaataactt
     1201 ttactttttt tccttctaag gctgcttcat gggcaaagac tgcaccaaca acaagataat
     1261 cgtacatctt aagctccttt ggagttcatt atctgcctct tttattagac tagaaaatca
     1321 ttctactact tatctcactt cttgtttgta aaattcttgc aatgcatctt gccaagttgg
     1381 aataacaaat ccagtagctt tggctttggc caggctcatc gttgagttta gcggacgttt
     1441 agctttggct ggaaattgac tggaatctac tggcttgact tcgacatctg tatctttcaa
     1501 aatttcaact gcaaaatcat accatgttgt gtcttctgtc gcatcatttg acaaatgata
     1561 ataaccaaat tccttacgat tttcagctag gtaggtcatg aactcagcca aggtacgagt
     1621 ccaagtcgga cgaccgtact ggtcatttac aactgttaaa gtcttatgag ttttcgcaag
     1681 attttgcatg gtaaaaacga agtttttgcc ataatttcca aatacccagg cagtacggat
     1741 aatatagaaa ttagacacat gcttctcaac taactcttcc cccatacgct tagtgcgtcc
     1801 atattctgtc tgtggatctg gtcggtcatc aacttcccac tcttgtccaa ctggtttctt
     1861 accgtcaaag acatagtccg tagaaatata aactagagtt gcaccatgct tttcagatgc
     1921 ttttgcgaca ttttttgtcc ccgtcacatt gatggcgaag tccaactctt ttccttcatc
     1981 ctctgctgca tcaacagcgg tgtaggctgc acagtggtag actaaagtcg gtttcacctc
     2041 ttcaaaaact ttctcaacca tttcttcatt ggtaatgtcc atctcagcca catctactgc
     2101 cacgtattct tcattacgtt catccaataa atagcgaagt tccgttccta attggccatt
     2161 tgcccctgta attaaaatca tctctagacc tttctaatat gtaactcttc tcaatatagc
     2221 aataaaaagc agctatttcc tgctttttat actgtaataa tctcctgagt cttagcataa
     2281 ttggcttcaa cagcttcttt ttctgctttc caccattctt ggttatctgt ataccacttg
     2341 attgttgcct tgagcccagc ttcaaagttg gtaaattcag gtttccaccc caactcatca
     2401 cggagcttgc tggcatcaat cgcatagcga aggtcatgtc ctgcacggtc agtcacatga
     2461 tcataggcat ccgtagcttg tcccatttcc ttaaggataa gttccaaaac ttccttattg
     2521 ttcttctcac catcagcccc aatcaagtag gtttcaccga tttgcccttt tgtcaagatt
     2581 gtccaaactc ctgaagaatg gtcattggta tgaatccagt cacgaacatt cttaccttca
     2641 ccgtaaagtt ttggcttaat tccacttagg atgttagtaa tctgacgtgg gatgaatttt
     2701 tcgatatgtt gataaggacc gtagttattt gaacagttgg aaatcgttgc cttgactcca
     2761 aaagaacgca cccaggcttt gacaatcaaa tctgaggctg ccttggttga tgagtacgga
     2821 gagcttgggt tgtattttgt ttcagcagta aatttctcac ctggtccttc accatgacct
     2881 ggcaaatctt cgcgtaaagg gagatcccca taaacttcat ctgtcgatac atggtggaag
     2941 cgaatatcat acttacgagc agcttctaaa agagtatagg ttccgatgaa gttagtatga
     3001 ataaatggcg atggatcatt gagcgaatta tcattgtggc tttccgctgc ataatgaacg
     3061 atagcatctg cttgagcagc caacttgtct accaactccg catcagcaat gtcaccaaca
     3121 actaactcaa cacgattacc taaaatttcc tcaatattcg cgcgatttcc agcataagtc
     3181 aacttatcta ggactgtcac gtgaacacct ggaaagttct cgtaaacata atggacaaag
     3241 ttagaaccga taaagccagc tccacctgtc acgataatat ttttgtattc agtcatattc
     3301 tttccttttt acaaatcttc ttttttcaaa ggttttacat ccttaagtag gggatgatgt
     3361 ttatctgctt ctgaaacctc tgcttctgca atattttccc attcaatacc aaggcttgga
     3421 tcagcgtagt tcacaaaggc atacttgggt ttgagctcga gagcccagta atcattgacc
     3481 agatagctat atgacactgt atctgataga acttggaagc cattagctac gcctcgagga
     3541 acaaagattc ccttgcttgc atcaattact gtctgatagg tattcccaaa ggtttcaccc
     3601 tcgcgtagat caacccaaga acccagaact ttccctccat ctgctacaga gatgtactta
     3661 tcccaaggct ctgcgtggag tcctcgaagg acatttttac gtgagaagga tacattgttt
     3721 tgcaattttc cttctgcaaa gaaagactct ggaaatccaa gtggaagcat tttttccttt
     3781 tggaaatttt ctttaaacca gccacgatta tctccatgaa cggggatatc aaactccaac
     3841 atgcctggaa tagcttcaac cttgcgtgcc gcaagcgtct taccgaaaaa attatctgtc
     3901 atctatgctt ctccaatcaa acggagcaga tactgtccgt attcattttt cttaagtggt
     3961 tgggctaagg tcaatacatc ttcacgactg atataaccca tgcgataggc aatttcttct
     4021 aagtttgcta cctgaacatt ttgcatccgt tggactgttt cgatgtactg tgaagcctct
     4081 agtaaacttt catgagttcc agtatccagc caagcaaagc cacgtcccat aagctcaaca
     4141 gacaaatcac cacgatctag gtaagctttg tttacatctg taatttccag ttcaccacga
     4201 ggacttggtt taatactctt ggcaatctct actacatcat tatcatagaa atagagacct
     4261 gtaactgcat agtttgaacg aggttgctct ggcttttctt caatagaaat agccttcata
     4321 tcctgatcaa actcaaccac accaaagcgc tctggatcct tgacatggta gccaaaaaca
     4381 gttgctcccg actccttact cgctgccttt tgtagcatct tggaaagccc agaaccatgg
     4441 tagatattat cacctaagat tagcgcaacg ctatcatcag aaataaactc ttccccaatg
     4501 ataaaggctt gtgccaaacc atctggactt ggttgctcag cataagaaag tttaatacca
     4561 aactcggaac catcttgaag aagctcttta aaacgaggca aatcttgagg agttgagata
     4621 atcaaaatat ccctaatccc agccaacatt aatgttgaaa gtgggtagta aatcatcggt
     4681 ttatcataaa ccggcataag ttgttttgat gcggctcgag tcaaaggata caagcgagtt
     4741 cccgaaccac ctgctagaat aatacctttc ataataagca acctttcttc gttgtttttc
     4801 aattactaaa ttctttctcc acaacctcaa gcgcccgttc aatcaccaca tgcatatcgt
     4861 aatacttata atctgctaaa cgcccacaaa agataacttt atcattctgc gctgcttctt
     4921 cttggtattt agcaaacata gcattatttt tctcatcgtt aataggatag tagggctcgt
     4981 ccccacgctt ccagtcagct ggatattcat gcgtgataac tgtctttggc tgcattccat
     5041 attcaaaatg tttgtgttcg atgatacgag tataagggat ctcacgctct gtatagttca
     5101 ctacagcatt cccttgataa ttttcctcgt ctaaaatctc atgctcaaaa cgaaggctac
     5161 ggtattctaa ctctccgtgc ttgtagtcaa aatattggtc gatcattcct gtgaagacaa
     5221 ctttgttagc agatgcttcc aactcttcac gatgagcaaa aaagtctact ccaagttcaa
     5281 cttctacatc tttcagcata ttttcgatga tgacattgta accaccaata ggaatccctt
     5341 ggtaacggtc attaaaatag ttattatcaa aggttaaacg aactggaagg cgttttatga
     5401 taaatggagg aagttctatc gctgagcgtc cccattgctt ttctgtataa cccttgatca
     5461 acttttcata gatatccgga ccaatcaact tgatagcttg ttcttccaga tttttcggct
     5521 caacatcctt cataccagct gtctgctcag caatcttatc cttcacttct tgtggagttt
     5581 ttgtgcccca catagcatag aaggtattca tattgaaagg aaggttataa agacttccct
     5641 tatagtttgc gacaggtgag ttgatatagt tgttaaactc agcaaattga ttgacgtagt
     5701 cccagacttt tttattagaa gtatggaaga tatgggcacc atatttatga acattgatac
     5761 cttctacatt ctcacagtat atgttccctc caatgtgatc gcgtttatca atcactttta
     5821 ctttttttcc acgctttgta gcttcgtgtg cgaagattgc tccagacaaa cccgctccaa
     5881 cgattaaata gtcgtacata attatctctt tctctttata atacctgtaa attcatatat
     5941 aataggattc ttcataaaaa cgttaattaa aaggaataca acacctccta acaaagttga
     6001 aaataacatt ttttctatat ccccaatata caattgcatt actacatata tagctccacc
     6061 catgattatt gttgaaacaa cagttggcaa ataaaatcct aagtcaaacc taattgtcac
     6121 acgttttttc gcatagtagt atgctgttaa agtaacaatt gtttcactaa tcacagatgc
     6181 caacgctgct ccattttgag ccattactgg aatcagaatt aggttcaaag cgatattact
     6241 aagcgctcct aaaattgtgc taatcaaaag ctttcgctca tctccaaatg ttagtaatat
     6301 ttgagtccca aataaattac taaaccctaa tgtacatata agcaaagaag taagttgaag
     6361 tgttaacact gctggtataa aactatcacc aaataaaatc ggcataatta ctggtgcaac
     6421 tagaattaat gcaacttggg ctggtaaaaa aagaaacaac atgattctaa aaactttatc
     6481 aacgatgtga tttaattttt caaattctcc cttagaataa taatcactta gtcgtggtaa
     6541 aagcactcct ccaatagcgg taatcacagt tatcagcaat ttaactagct tcatagaatt
     6601 tgtataataa cctacctcag tcgttcctac catagcacca atcatagtgg tatccagcat
     6661 agtatagatt tcaatagcaa tcactgaacc caacaaaaca aaaataggtt ttaagtgtct
     6721 tctaatctta at
//
LOCUS       DAVLZG010000081         6103 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLZG010000081 DAVLZG010000000
VERSION     DAVLZG010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.081"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            36..722
                     /locus_tag="VYO72_001887"
     CDS             36..722
                     /locus_tag="VYO72_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1708202.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            723..1655
                     /locus_tag="VYO72_001888"
     CDS             723..1655
                     /locus_tag="VYO72_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1708203.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1666..2595
                     /locus_tag="VYO72_001889"
     CDS             1666..2595
                     /locus_tag="VYO72_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1708204.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2609..4048
                     /locus_tag="VYO72_001890"
     CDS             2609..4048
                     /locus_tag="VYO72_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708205.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4117..5694
                     /locus_tag="VYO72_001891"
     CDS             4117..5694
                     /locus_tag="VYO72_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1708206.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5754..>6103
                     /locus_tag="VYO72_001892"
     CDS             5754..>6103
                     /locus_tag="VYO72_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1708207.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKV"
BASE COUNT         2066 a          841 c         1181 g         2015 t
ORIGIN      
        1 ttagtaaaaa aaataaaaaa acggaggttt tctgaatgga aactaaaaaa attaaaaatt
       61 taaaaggtca aataattgtt tcctgccaag cgttagaagg agagccactt tatactccaa
      121 atggaggagt gatgccgtta ttagcaaaag ccgcctttca agcaggcgct aaaggtattc
      181 gtgctaattc tgtccgcgat atttcagaaa taaaagaaga agttgactta ccaattatag
      241 gtatcataaa aagagattac gatggctttg aaccttttat ttcagcaact atgaaagaga
      301 ttgatgaatt agttagtgaa ggagtagaca ttttagcttt ggattgtact aatcgttcaa
      361 gaccaggtta tgataatatt actgacttta ttcatgatat taaagtcaag tatccaaacc
      421 aattattaat ggctgatatt tctacttttg aagaagggaa agtagctgct gaatcgggag
      481 tagattttgt gggtacgaca ttatctggtt atacaccata tagccctaaa aaagataatc
      541 ctgattttga gttagttgaa agattggtaa aagagcttga cgtaccagtt attgctgaag
      601 gaagaataag tactccggaa caagctagaa aaatgttaga tttaggtgct tacgcagtgg
      661 ttgttggagg agctatcact cgtcctttgg aaatagcgaa gaagtttatt gaggtagttt
      721 agatgaatca agaaatatta aaaaagagta agattcaatt gacagttgaa catattcaaa
      781 aatattggat tttatattta atgatgattc cagcaactgt tctactaatt ttatttacgt
      841 atggaccaat gtacggcatt attatggcct ttcaagactt tactgtcttc aagggatata
      901 ctggaagtcc atttgtcggt ttaaaacatt ttcaaagatt gttctcagat cctttgtttt
      961 atagattgtt caagaatacg ttcatggtag gggttttaga ctttttattc tctttcccag
     1021 ctccgcttat ttttgcactc atattaaacg aagtcagaaa agtaagattt aagagtgtag
     1081 ttcaatctat tagttatctt cctcatttta ttcccctagt ggttatggtt ggtattattt
     1141 ttgaactatt tggttcatat ggtattatta acagtttact ttcatcactt ggaatggagc
     1201 caataagttt ctttacaaaa tctgaatggt tcttgcctct ctacattggt tcaggagtat
     1261 ggaaaacaat aggttggggt tctatcattt atatgggagc attaaccaat atagattcaa
     1321 ctttatatga agcagcagat atggacgggg ctaatagatg gcacaaaatg tggcatgtaa
     1381 ctctaccaag tttaagacct acagtagtta ctttgtttat actaaatgct ggtggtatca
     1441 tgcaagtagg atttgaaaag gtattcttga tgtctagtcc tgcaacatat gaagtatctg
     1501 atgtattatc tacttatgtt tatagacaag gtattttaaa ttctgatttc agttactcag
     1561 ctgcagtagg attatttaat aacatagtag ctttgttatt tgttttatta gctaataaga
     1621 ttgctaaaaa acttggcgaa gaaggaattg tataaggggg gtaaaatgat tttttcaaaa
     1681 aatacaaaaa agagtaatag agacaaagaa accttcgttg attatctctt tatattcatt
     1741 ttaataataa taaccttact tatgttgtat ccattatggt gggtagtgat gacgtcactt
     1801 tcagaaccag tttggctatc taaaaacgtt gttaaattat ttcccttaaa aatagatatt
     1861 actgcatata agtttatttt tggggattct aaactatggc aagcatatgg taatagtgta
     1921 ttgtatgctg cactatctac aattgttagt gttgcggtat gtagtatgta tgcctatcca
     1981 cttacaattc ctgaaattag gggtaaaaaa ttctggaata ctcttatttt gattccaatg
     2041 ttctttagtg gaggaatgat cccgctttat atacaagttg caaacctcgg tttattgaat
     2101 actgcttggg ctcttgtttt acctggtgct gtttctacat attatataat tttgtttaga
     2161 acacagttta aatcaatccc aatggagctt cgtgagtctg ctagaattga tggggcaagt
     2221 gaatttagaa ttttttggaa tttagtatta ccattatcaa aagttatttt catgattata
     2281 gcactttatt gcatagttgg ttcatggaat agttttactc ctccattact ttatttgaat
     2341 gacgacacta agatgccttt atctatttat ttgagaaatt tagttgttac aaatacaact
     2401 gatactgctg aattatcact ttctgcaggt aatacatatt accaacaaat tgctgctcaa
     2461 ggtggaggta ttggtatgcg tattgctatt aagatgggta ctattgttgt tagtgttatt
     2521 ccaattatga tgatttatcc atttattcag aaacattttg ttaagggaat cctgctaggt
     2581 tctgtgaaag gttaataagg taattatttt gcaaaattta aaaaaatatc ttttattaga
     2641 tagcggttta gtagttgggt atacattaga aaatgctcaa ttaaaattaa ataagctaaa
     2701 aaaagatact gaaaacaatc cactatttgg tgaagagtat tttgccgaaa atcctaaatt
     2761 atgggaagtt cgttttgata attcatatcc aaacgttatc tatgataaag aattgaaatt
     2821 atatagatgt tggtatcaaa catttgttag tgatgaagca agcgaagaga ctcctttagc
     2881 agaacgtgga gagaaggaat acattgtcaa gtcatctaga atgacagcac tttgctatgc
     2941 tgaaagtaaa gatggagtaa aatgggaaaa accaaatctc aatctagtaa aatttaaagg
     3001 ttcaaaagat aataatattg ttctgatgca tgcacacggt gcaggtatca tgctagatga
     3061 acaggagttg gatcctaaga aacgatataa attagtttca aaattagaat tttctccgaa
     3121 tcttcattac atggttgttg ttttttcaga agacggtatt cattttgacg aacctattcc
     3181 atggaaaaaa tggaatcctg cagcagatag tcataatttt ccatttagag atccaaaaac
     3241 tggtaaatac gctgttatta caagaacctg ggcaaataac gtacgtctaa gtgcaattac
     3301 tttcagtgat gattttatta attggtcaga acctaaagaa atccttaggg gagatggatt
     3361 tgaagatcaa atttattcta tgccagtaat ttcatacgcg gatatctatt taggttttgc
     3421 ttcaatgtac cacgaaggcg acactttaaa tgaaaactat gataaagtag acttagaatt
     3481 gaaattctct gctaatttgg aacaatggga tagtgtatgt aagggcgact atctcattga
     3541 aaggggaggt ggagtatacc cgcagaatgc tgattttgat gctagttgta ttttcacggc
     3601 tgctccaata attgaagatg ataagatttg gttctactat atgggtggaa atggtaatca
     3661 cactggcttc cgagaaagtt cattagctag aggatatatt aagaaagacc aatttgctta
     3721 ttatactaat aagagagaag gaattccagc taaaatatct acagttagct tccaaactta
     3781 cgatgatgaa atttatatct tagctgatat tcctgaaaat ggttatatta aagttgcggt
     3841 aggtactaaa tacggtaatg cttattcaga ttttggtcag gaagatatct ctcttgttca
     3901 agtttccgat ggtaagtata agttggaatt taataaaaaa tctatcttag atttaggtaa
     3961 ttctccagtt gcgttcaaat ttgaaatcga gaatgcaaaa ttgtatggta ttgaaggtag
     4021 tattcagcaa cactatctca aatattaacc agaataattc gttaacaaat aatctctata
     4081 ttagtggaga tagatatata aaatggaggt cttattatgg taaagcttaa taaggtatta
     4141 aaagggagtg ttgcattcct gagtgcaagt ttattgctag cagcttgtgg caataacgct
     4201 aattcaaagc ccgctgaaaa aacagctgat ggtaaaacga aaatttcgtt tctatctaca
     4261 tggcaaatta atgatgttcg tccgcctaaa gatgaaacac ttgttggtca atggttagaa
     4321 gaacagctag gtattgatat tgatcttgta actattcctg gcgagggagt aagttctaaa
     4381 gtaaattctc ttattactag taaccagtta ccgactgttt tgttgacaac aggagataag
     4441 agtgatatcg ctggtatcaa caaacttggt aaacagggtg cattcttaga tttgtcacaa
     4501 cacatggaca aactaccaaa ctataagaag taccttgaaa aaaataatgc attagctcaa
     4561 atagaagatg atgaaaaaca tatttatgct ttcacaaaat tctttactga tgagaatatc
     4621 atgtatacta caccaattct gagaaaagac ttacttgttg gttcagaatt tgaagatctt
     4681 tcaaaaatta aaactgttga tgactataca aaagttttga aatatttgac tgaaaaacaa
     4741 ggttctccag catttattca acgtaatggc tatgaaggct tcatgaagcg agttacacca
     4801 ttgtggaatt taagccatcg tacatactat gactatgaat cagattcata taaacatcca
     4861 gttgaacaac ctcaattgaa acaattcgtt gaatggttga aagaattacg taaagataac
     4921 gtacttcacc ctgactgggc agttatgaaa gatgaaactt gggaaggtct attggcttct
     4981 aacaagggtt cattcactgt tgaccgtatg aatatcattg gagataataa ctttgataaa
     5041 tcatttgatt ggcagccact tgtttatcca aaaattaatg gaaaacgtta tttgcaaccg
     5101 aaaacaccgt acatttctga ttcaggttgg gtaatcaatg ccaatgcacc aaaagaagaa
     5161 attgataaag cgttagaatt ctttaatttc ttatacgctg atgaaaatca agaaaaactt
     5221 gctattggat ttgaaggtaa aacatttaca cgtgaaaacc ctaatactca agcaggtatt
     5281 aaatggttga ttcaaattta cggtgaaaat gctggaaatg ataaagcaga actgctgttt
     5341 aaacatggta accaagcatt tactcgcgtt caaactaaat tagatattga ggcacagcca
     5401 ggaacattcc ctaaagttat gtatgatcaa gtagataaaa ttaagaaaga tttaggtggt
     5461 tttagaccag atactccggt tctttccttt acaactgaag aattagatgt tttaactaaa
     5521 tctgaagcag gattaaatac tttctttgat gaaaatatta ttaaattcat tgaaggacaa
     5581 agagatatga gtgagtggga ttcatttatc aatgaagcta aatctaaaga cttggataaa
     5641 gttacaaaag tatataatga tgcctacaaa cgtgtcaaag atagaatgaa atagactaaa
     5701 tggtagctct ctggtttttc agagagctac tactgcctga gggggagtaa gctttgtatg
     5761 atgtagtaat tataggtgca ggaagttcgg gcgcattggc tgcaattgct tcggggcgtc
     5821 tagggttaaa aacttgtcta atagagaagg gaagtagaat tggtggagtt cctattaata
     5881 cactaatggg gtcatttgct aatctatatt ttgatgattc tggtagagta aatgcaagta
     5941 aaattgttgg ggaattaata gaacgtatta tcaaaaaagg tggtactgtc tttaactcta
     6001 tggaagaatt gatgaatgta aatgattttt atcagattac aattccctat caaccagaag
     6061 tttatgaatc ggttttaact gatatgttga ttgagtctaa agt
//
LOCUS       DAVLZG010000082         6005 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLZG010000082 DAVLZG010000000
VERSION     DAVLZG010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.082"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            120..887
                     /locus_tag="VYO72_001893"
     CDS             120..887
                     /locus_tag="VYO72_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1708208.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLSVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            972..1379
                     /locus_tag="VYO72_001894"
     CDS             972..1379
                     /locus_tag="VYO72_001894"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708209.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNIIFAKLPSGRH
                     PESRWPWLKSRAEINGIIAVLAGILVYGGVLLV"
     gene            complement(1749..4301)
                     /locus_tag="VYO72_001895"
     CDS             complement(1749..4301)
                     /locus_tag="VYO72_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1708210.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQALKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISITSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTYKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(4363..5985)
                     /locus_tag="VYO72_001896"
     CDS             complement(4363..5985)
                     /locus_tag="VYO72_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1708211.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
BASE COUNT         2011 a          986 c         1108 g         1900 t
ORIGIN      
        1 atttagattt tttaatgtat aatctattat atcaaaattt tagacaatat gtttaaaaaa
       61 ggagaaacta tgtttaaaga atggaaagca atttaaaaaa aacaaccttt attattgtca
      121 tgatcgggat ttctcttatt ccagctctgt acaatatcat atttttgtca tcaatgtggg
      181 atccatatgg gcaattgtct gacttatctg tggcagttgt aaataatgat aaagaggctt
      241 cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta aaagaaaata
      301 aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg gaagatggcg
      361 attactatat ggtagtgact ttaccaagtg atttatctaa aaaaacaact acattatcca
      421 atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact gggataagtg
      481 attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt gtagctttag
      541 tacaaggttt acagggaagt ttagaaaact tacaaaatca atcttctaat ctttcgactt
      601 taaaaaatca agctaatcaa gtattaccta ttacttctac ttctttgata ggattgtcaa
      661 gtggattaac agagatacaa ggagctgtta ctagcaaatt agttcctgcc agtcagttga
      721 ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag ggcgcaagtc
      781 aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt tcaggctcaa
      841 acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta caatcaggat
      901 ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca ttagagaata
      961 gagctaataa attggcagat ggatctggga aactagcaga aggtggaaca aagttaactt
     1021 ctggattgga agatttacag acaggacttg cttctttagg acaaggacta ggtaatgcta
     1081 gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg tcaaatccac
     1141 tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca atagctcctt
     1201 atatgatatc agttgctctt tttgttgcag caatatcaac aaatataata tttgcgaaat
     1261 tgccttcagg acgtcatcca gagagccgtt ggccttggtt gaaatctcga gctgaaataa
     1321 atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcta ttggtttaac
     1381 tgctaatcat gagatgagaa tatttattct catcatccaa acaagtttag tattcatgtc
     1441 tatggtgacc actttagcaa cgtggaatag ccgtatagga gcttttttct cacttatttt
     1501 gcttttacta tagttagcat caagtgcagg tacttatcca cttgctttga caaatgattt
     1561 ctttagatct attaatccct gtttaccaat gagctattca gtttcgggat tacgacaaac
     1621 aatctctatc aacaagtcat tttcctagct gtcatactag ctctatttac tggtttaggt
     1681 atgctagcct atcaacataa gaaaatggaa gaagattaaa aaaatcgacc gattaactgg
     1741 tcgatttttt atgccttaga tgactttcgt ctgtgattat agattccaaa tagtaagaga
     1801 gaagtaaagg aacagattgc tccagtaata aaaccattgg gaatgaagga aagtgtaata
     1861 gttcctttcc ccttgggaat gtcaactttc ataaatccag tttgagcttg tttaatttct
     1921 attttcttac catcttggta ggcagaccaa cctttgtcat aaggaatggt gaagaaaata
     1981 gatgtatctt gttggacatc atatgtagca aaaaccttgt ttttataagt tgatactgtg
     2041 acaggttgtt ctttaatttt ttgaattgcc tcggtgaaag ttttggtatc taaacgatag
     2101 aaggtaggag attcaaatga tacttgtgaa tttccaggga aactaacatt gatattgaaa
     2161 gtttttttct ctttagtata tcctagatta aagaaggaga agacattatc agttgtaaaa
     2221 gtcttttttt caccatttac aaggatgtca accttctttt gtttatcgtt agaaaagtga
     2281 aggtttatga aagagagata aacttggctg ttttctggaa cttcaatttg atactggatt
     2341 gctgcatctt catttgaaga acttgtgata ctaatcaaat cattagtatt ttctattttt
     2401 tctgtttttt cataaggtat tggagaaaaa taatcaaaat tgacgttagc aagttgattt
     2461 aaaaatgagg cctgattatc caaggtatgt tcattgaact tgacatcatt gtaaacagat
     2521 tgactagcaa ctgcaatcgg aagagagtat tgattttcat atagggtaag attatctttt
     2581 tgatagatat ctttaaagcc atacttatca ataggactgt ctgagatatt gtactggata
     2641 ccaaataaac tatcagccaa aatactatta tttgcatatc ggagattgag attagtccca
     2701 gaggatttaa aaccaagttt atctaaagta gagcttgatg aacgatttcg aacagatgaa
     2761 aattgagaga ttccattgta gttgaatttc atactgtcat ttcctgtctg agtttgtagt
     2821 ttttcagtac gagtaaattg atttccaata tatgttgaga aagattccat agctgggata
     2881 tctcgactat aagcacttcg agaagcaaat ccccattcct tagcaattcc gtccatttga
     2941 gatgaagcat ttaaactcat ttcaaccagt ataaataaag agattagaat ggcaaataga
     3001 tttacagata taaacttttt gataactgca aggagtaaaa gagaatagac aaccaaaaat
     3061 tcaagagtaa gcagaatatt caaatctgtt aaaaaagaat aatgcgattt tagatagatg
     3121 gtagctaaaa atcctgctac tacaagaaaa agcgaaacta aaaaattcca gactttaagt
     3181 tctttcagac gctttaagac ttctgctgct gtgtaaatta acaaggtaga gaaaatccaa
     3241 gcatagcgat gtaaaaacat gtttggagta tgcatgcctt gccaaaataa gtcaagagct
     3301 tctatgtaaa agcttgcaat tagaaatgca aagaatatta catatatgag tttcacgtga
     3361 aacttaatag atttcagcgt aaaaaataaa atggtcaaaa taaagggaaa tagtccaaca
     3421 aaaatcattg ggatggcccc atactttgtt gtgtcaaagg aaccaatgaa ttgcttagca
     3481 aagagatcaa gataccagct actttcagtt tgaaactttg taacttcagt caatttttcc
     3541 ccatgtgtct gtaaatcaaa tagagtggga agagtcataa tcaaactagc cataccagct
     3601 aaaaaggaga taactatgaa atcaagaaca gatgattttc gagtcttaaa gtcccacgaa
     3661 atttgacaga gataccagaa aataagaaac aatactgtca tatatccaaa ataataattt
     3721 tgaataaata agattgacag acttgtaaag tacaatagga gtttcttttc agttatcagt
     3781 agatgtaaac cagttataat taaaggaatc aagataaaaa catctagcca ggtttttatc
     3841 tctaattgac tgacagtgaa actcatcaga gcataggaag tagataaggc tagttttaaa
     3901 gcctgaggga tagattgaaa caatttattc aaactaaaaa aggttgacag accaatcaat
     3961 ccaaatttta agagagttgt cagatagata gcatctggca tattcgttag atcaaaaaag
     4021 taaaccagag gcgcgagaaa actacccaag taataactag atagggcata gaagtttagc
     4081 cctagaccac ttgtaaaggt gtaaaacaga ctactatttc catgtaggat atttcgtaag
     4141 gctacatcaa aaataacgta ttgatgaaag ccatctccta atagaggaga gttgtcgcta
     4201 ttccagtaga taccttgaga tagatatact ccagacataa tcactacagg aatgatgaaa
     4261 gaaataaaat aggttcgata tgtttttaaa aatgatttca tgttacctcg tagaatgata
     4321 gaaaactcag ttggttaacc caactgagtt ttgaagtttt atttagtctt tccaaagttc
     4381 tttaactttt gcttgtactt ctgcattttc taggaattca tcgtaggttt catcgatacg
     4441 gtcaatgacg ccatttttag ataagacaat gatatggtta gccaaagttt gaataaattc
     4501 gtggtcatgg ctggcaaaga tgattgattc tttaaagttt ttcaatccat cattcaagct
     4561 tgagatagat tccaagtcca agtgatttgt tggatcatca agtacaagga catttgattt
     4621 taagagcatg agttttgaaa gcatgacacg aactttttct ccccctgaca agacatttac
     4681 aggtttgtta acttcatctc cagagaagag catacggccg aggaagccac gtaggaaagt
     4741 attgtcatct tcttctttac ttgcgaattg acgcaaccag tcaagaattg attctcctcc
     4801 tgcaaaatca gctgagttat cttttggtag gtaagattga ctagttgtaa ctccccactt
     4861 gacagttcct tcatagtcaa tatctcccat gattgcacga attaatgcag tcgtttgaat
     4921 atcattttgt ccaataagtg ctgtcttatc atctggacgc aagatgaaac taatattatc
     4981 caagatagtt tcaccatcaa tctttacagt tagattttct actgtcaaga gatcattacc
     5041 aatctcacgt tccgctttaa agttgataaa tggatattta cgactagatg gtacaatctc
     5101 ttctagctca atcttatcaa gcattttctt acgtgatgtt gcctgccttg acttagaagc
     5161 attggcagag aaacgagcaa cgaattcttg caattgttta attttttctt ctgctttagc
     5221 attacggtct gctagcaatt tagcagcaag ctcagaagat tccttccaga agtcgtagtt
     5281 tccgacatag agtttgattt ttccaaagtc aaggtcggcc atgtgagtac aaactttgtt
     5341 taagaagtga cggtcgtggg atactacgat aactgtgtta tcaaagtcaa tcaagaagtc
     5401 ttctaaccaa gtaatcgatt ggatatccaa accgttagta ggctcgtcca agagaagaac
     5461 atctggttta ccaaaaagtg ctttggcgag gagaaccttt actttttcac cgttggccaa
     5521 ttcgctcatg ttttggtagt gtaattcttc tggaatgttt aggttttgaa gtagttgaga
     5581 ggcttcactc tctgcttccc aacctccaag ttcggcaaac tctccttcga gttcggcagc
     5641 acgaaccccg tcctcgtctg agaaatcttc cttcatgtag atagcatctt tctctttcat
     5701 gatgctataa agtttttcat ttcccatgat aacgacatca atggcacgtt catcttcgta
     5761 gtcaaagtga ttttgacgaa gaacagagag acgttcatct ggaccaagag agatgtgacc
     5821 agtagtaggt tcgatatctc cagctaaaat ttttaaaaag gttgattttc cggcaccatt
     5881 agcaccgatt aatccgtaag tatttccttc tgtaaatttg atattgacat catcaaaaag
     5941 tttgcgatca ctaaaacgta gtgaaacatc agatactgta agcaatattt ttctcctata
     6001 tgtgt
//
LOCUS       DAVLZG010000083         5870 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLZG010000083 DAVLZG010000000
VERSION     DAVLZG010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.083"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            105..584
                     /locus_tag="VYO72_001897"
     CDS             105..584
                     /locus_tag="VYO72_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1708212.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VYO72_001898"
     tRNA            678..749
                     /locus_tag="VYO72_001898"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1003..2548
                     /locus_tag="VYO72_001899"
     rRNA            1003..2548
                     /locus_tag="VYO72_001899"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2600..2672
                     /locus_tag="VYO72_001900"
     tRNA            2600..2672
                     /locus_tag="VYO72_001900"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2633..2635,aa:Ala,seq:tgc)
     gene            2797..5698
                     /locus_tag="VYO72_001901"
     rRNA            2797..5698
                     /locus_tag="VYO72_001901"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5775..>5870
                     /gene="rrf"
                     /locus_tag="VYO72_001902"
     rRNA            5775..>5870
                     /gene="rrf"
                     /locus_tag="VYO72_001902"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1727 a         1138 c         1674 g         1331 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ttagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa aggctgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc ggttggaaca cttgatgaaa
      781 aaaagtttaa aaaaagctta aaaatcttca aaaaagtgtt gacaagtgaa agtggctgtg
      841 atatactaat atagttgtcg cttgagagaa gcaagtgaca aagacctttg aaaactgaac
      901 aagacgaacc aatgtgcagg gcgctacaac ataagttgta gtactgaaca atgaaaaaaa
      961 caataaatct gtcagtgaca gaaatgagta agaactcaaa cttttaatga gagtttgatc
     1021 ctggctcagg acgaacgctg gcggcgtgcc taatacatgc aagtagaacg ctgaaggagg
     1081 agcttgcttc tctggatgag ttgcgaacgg gtgagtaacg cgtaggtaac ctgcctggta
     1141 gcgggggata actattggaa acgatagcta ataccgcata agagtggatg ttgcatgaca
     1201 tttgcttaaa aggtgcactt gcatcactac cagatggacc tgcgttgtat tagctagttg
     1261 gtggggtaac ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
     1321 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
     1381 tggacggaag tctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
     1441 tctgttgtaa gagaagaacg agtgtgagag tggaaagttc acactgtgac ggtatcttac
     1501 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
     1561 tccggattta ttgggcgtaa agcgagcgca ggcggttaga taagtctgaa gttaaaggct
     1621 gtggcttaac catagtaggc tttggaaact gtttaacttg agtgcaagag gggagagtgg
     1681 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
     1741 ctctctggct tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
     1801 ccctggtagt ccacgctgta aacgatgagt gctaggtgtt agaccctttc cggggtttag
     1861 tgccgtagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1921 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1981 aagaacctta ccaggtcttg acatccctct gaccgctcta gagatagagt tttccttcgg
     2041 gacagaggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     2101 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttcagttggg cactctagcg
     2161 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     2221 gacctgggct acacacgtgc tacaatggct ggtacaacga gtcgcaagcc ggtgacggca
     2281 agctaatctc ttaaagccag tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     2341 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     2401 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taaccgtaag
     2461 gagccagccg cctaaggtgg gatagatgat tggggtgaag tcgtaacaag gtagccgtat
     2521 cggaaggtgc ggctggatca cctcctttct aaggataagg aactgcgcat tggtcttgtt
     2581 tagtcttgag aggtcttgtg gggccttagc tcagctggga gagcgcctgc tttgcacgca
     2641 ggaggtcagc ggttcgatcc cgctaggctc cattggtgag agatcaccaa gtaatgcaca
     2701 ttgaaaattg aatatctata tcaaatagta acaagaaaat aaaccgaaaa cgctgtagta
     2761 ttaataagag tttatgactg aaaggtcaga aaataaggtt aagttaataa gggcgcacgg
     2821 tggatgcctt ggcactagga gccgacgaag gacgtgacaa acgacgatat gccttgggta
     2881 gctgtaagta agcgatgatc cagggatttc cgaatggggg aacccaacag gtaatacctg
     2941 ttacccacat ctgttaagga tgtgaggagg aagacgcagt gaactgaaac atctaagtag
     3001 ctgcaggaag agaaagcaaa agcgattgcc ttagtagcgg cgagcgaaac ggcagaaggg
     3061 caaaccgaag agtttactct tcggggttgt aggactgcaa tgtggactca aagattatag
     3121 aagaatgatt tgggaagatc agccaaagag agtaatagcc tcgtatttaa aatagtcttt
     3181 gtacctagca gtatcctgag tacggcggga cacgtgaaat cccgtcggaa tctgggagga
     3241 ccatctccca accctaaata ctccctagtg accgatagtg aaccagtacc gtgagggaaa
     3301 ggtgaaaagc accccgggag gggagtgaaa tagaacctga aaccgtgtgc ctacaacaag
     3361 ttcgagcccg ttaatgggtg agagcgtgcc ttttgtagaa tgaaccggcg agttacgtta
     3421 tgatgcgagg ttaagttgaa gagacggagc cgtagggaaa ccgagtctga atagggcgcc
     3481 ttagtatcat gacgtagacc cgaaaccatg tgacctaccc atgagcaggt tgaaggtgcg
     3541 gtaagacgca ctggaggacc gaaccagggc acgttgaaaa gtgcttggat gacttgtggg
     3601 tagcggagaa attccaaacg aacttggaga tagctggttc tctccgaaat agctttaggg
     3661 ctagcgtcga cattagagat tcttggaggt agagcactgt ttgggtgagg ggtccatccc
     3721 ggattaccaa tctcagataa actccgaatg ccaatgaatt atggtcggca gtcagactgc
     3781 gagtgctaag atccgtagtc gaaagggaaa cagcccagac caccagctaa ggtcccaaaa
     3841 taattgttaa gtggaaaagg atgtggggtt gcacagacaa ctaggatgtt agcttagaag
     3901 cagctattca ttcaaagagt gcgtaatagc tcactagtcg agtgaccctg cgccgaaaat
     3961 gtaccggggc taaaacaatt taccgaagct gtggatacct ttataggtat ggtaggagag
     4021 cgttctatgt gtgatgaagg tataccgtga ggagtgctgg aacgcataga agtgagaatg
     4081 ccggtatgag tagcgaaaga caggtgagaa tcctgtccac cgtaagacta aggtttccag
     4141 gggaaggctc gtccgccctg ggttagtcgg gacctaagga gagaccgaaa ggtgtatccg
     4201 atggacaaca ggttgatatt cctgtactag agtatgtagt gatggaggga cgcagtaggc
     4261 taactaaagc agacgattgg aagagtctgt ctaagcagtg aggtgtgaat tgagtcaaat
     4321 gcttaattct ataacattga gctgtgatgg ggagcgaagt ttagtagcga agttagtgac
     4381 gtcacactgc caagaaaagc ttctagcgtt taaacatact ctacccgtac cgcaaaccga
     4441 cacaggtagt cgaggcgagt agcctcaggt gagcgagaga actctcgtta aggaactcgg
     4501 caaaatgacc ccgtaacttc gggagaaggg gtgctgactt taagtcagcc gcagtgaata
     4561 ggcccaagca actgtttatc aaaaacacag ctctctgcta aatcgtaaga tgatgtatag
     4621 ggggtgacgc ctgcccggtg ctggaaggtt aagaggagtg cttagcgtaa gcgaaggtat
     4681 gaattgaagc cccagtaaac ggcggccgta actataacgg tcctaaggta gcgaaattcc
     4741 ttgtcgggta agttccgacc cgcacgaaag gcgtaatgat ttgggcactg tctcaacgag
     4801 agactcggtg aaattttagt acctgtgaag atgcaggtta cccgcgacag gacggaaaga
     4861 ccccatggag ctttactgca gtttgatatt gagtgtctgt accacatgta caggataggt
     4921 aggagtctaa gagatcggga cgccagtttc gaaggagacg ctgttgggat actacccttg
     4981 tgttatggcc actctaaccc agataggtga tccctatcgg agacagtgtc tgacgggcag
     5041 tttgactggg gcggtcgcct cctaaaaggt aacggaggcg cccaaaggtt ccctcagaat
     5101 ggttggaaat cattcgcaga gtgtaaaggt ataagggagc ttgactgcga gagctacaac
     5161 tcgagcaggg acgaaagtcg ggcttagtga tccggtggtt ccgtatggaa gggccatcgc
     5221 tcaacggata aaagctaccc tggggataac aggcttatct cccccaagag ttcacatcga
     5281 cggggaggtt tggcacctcg atgtcggctc gtcgcatcct ggggctgtag tcggtcccaa
     5341 gggttgggct gttcgcccat taaagcggca cgcgagctgg gttcagaacg tcgtgagaca
     5401 gttcggtccc tatccgtcgc gggcgtagga aatttgagag gatctgctcc tagtacgaga
     5461 ggaccagagt ggacttaccg ctggtgtacc agttgtcttg ccaaaggcat cgctgggtag
     5521 ctatgtaggg aagggataaa cgctgaaagc atctaagtgt gaaacccacc tcaagatgag
     5581 atttcccatg attatatatc agtaagagcc ctgagagatg atcaggtaga taggttagaa
     5641 gtggaagtgt ggcgacacat gtagcggact aatactaata gctcgaggac ttatccaaag
     5701 taactgagaa tatgaaagcg aacggttttc ttaaattgaa tagatattca attttgagta
     5761 ggtattactc agagttaagt gacgatagcc taggagatac acctgtaccc atgccgaaca
     5821 cagaagttaa gccctagaac gccggaagta gttgggggtt gccccctgtg
//
LOCUS       DAVLZG010000084         5606 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLZG010000084 DAVLZG010000000
VERSION     DAVLZG010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.084"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..623
                     /locus_tag="VYO72_001903"
     CDS             <1..623
                     /locus_tag="VYO72_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1708213.1"
                     /translation="KKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKP
                     QPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQ
                     GRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTA
                     VKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            713..1909
                     /locus_tag="VYO72_001904"
     CDS             713..1909
                     /locus_tag="VYO72_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1708214.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            2045..2572
                     /locus_tag="VYO72_001905"
     CDS             2045..2572
                     /locus_tag="VYO72_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1708215.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            2649..3005
                     /gene="glnR"
                     /locus_tag="VYO72_001906"
     CDS             2649..3005
                     /gene="glnR"
                     /locus_tag="VYO72_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1708216.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            3042..4388
                     /gene="glnA"
                     /locus_tag="VYO72_001907"
     CDS             3042..4388
                     /gene="glnA"
                     /locus_tag="VYO72_001907"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1708217.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(4484..4603)
                     /locus_tag="VYO72_001908"
     CDS             complement(4484..4603)
                     /locus_tag="VYO72_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1708218.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            5091..5606
                     /locus_tag="VYO72_001909"
                     /pseudo
     CDS             5091..5606
                     /locus_tag="VYO72_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         1792 a         1006 c         1149 g         1659 t
ORIGIN      
        1 ttaagaaagt atttttctta cctgaaggca aagaggcagt agaattggct tttgaacaaa
       61 cggatagtca tgttatcttt acagcaccac actttactca ttatgccttt gtttatgaat
      121 ctgctgaaaa accacaacct gctaaaccag caccacaaaa caaagtcctt ccaaaaccta
      181 cttatcaacc ggcttctgat caacaaaagg ctcctaaatt ggaagttcaa gaggaaaagg
      241 ttgcctttca tcgtcaagag catgaaaata ctgagatgct agttggggaa caacgagtca
      301 tcatacaggg acgagatgga ctgttaagac atgtctttga agttgatgaa aacggtcagc
      361 gtcgtcttcg ttcaacagaa gtcatccaag aagcgattcc agaaattgtt gaaattggaa
      421 caaaagtaaa aacagtacca gcagtagtag ctacacagga aaaaccagct caaaatacag
      481 cagttaaatc agaagaagca agcaaacaat tgccaaatac aggaacagct gatgctaatg
      541 aagccctaat agcaggctta gccagccttg gtcttgctag tttagccttg accttgagac
      601 ggaaaagaga agataaagat taaatatcga aaaatcttgt gaaatctttc cttatatttc
      661 caaagtgtga tataatagtt tcgaataaaa taaataaagg agtttttgta acatggcaaa
      721 acttactgtt aaagacgttg acttgaaagg taaaaaagtc ctcgttcgtg ttgacttcaa
      781 cgtaccattg aaagatggcg taatcactaa cgataaccgt atcacagcag ctcttccaac
      841 tattaagtac atcatcgaac aaggtggacg tgcaattctt ttctctcacc ttggacgtgt
      901 gaaagaagaa gctgataaag ctggtaaatc acttgctcct gtagcagctg acttggcagc
      961 aaaacttggt caagatgttg ttttcccagg tgtcactcgt ggtgctgaat tggaagcggc
     1021 aatcaacgct cttgaagatg gacaagttct cttggttgaa aacactcgtt acgaagatgt
     1081 tgacggcaag aaagaatcta aaaacgatcc tgaacttggt aaatactggg catcacttgg
     1141 agatggtatc ttcgtaaacg atgcattcgg tacagctcac cgtgcacacg catctaacgt
     1201 tggtatctca gcaaacgttg aaaaagcagt tgctggtttc cttcttgaaa acgaaattgc
     1261 ctacatccaa gaagcagttg aaactccaga acgtccattc gtggctatcc ttggtggttc
     1321 aaaagtttca gacaagatcg gtgttatcga aaacttgctt gaaaaagctg ataaagtcct
     1381 tatcggtggt gggatgactt acacattcta caaagcacaa ggtatcgaaa tcggtaactc
     1441 acttgtagaa gaagacaaat tggatgttgc gaaagctctt cttgaaaaag caaatggtaa
     1501 attgatcttg ccagttgact caaaagaagc taacgcattt gctggttaca ctgaagtgcg
     1561 tgacactgaa ggtgaagcag tttctgaagg cttccttggt cttgacatcg gtccaaaatc
     1621 tatcgccaaa tttgacgaag ctttgactgg tgccaaaaca gttgtatgga acggacctat
     1681 gggtgtattt gaaaacccag atttccaagc tggtacaatc ggtgtgatgg acgctatcgt
     1741 gaaacaacca ggagttaaat caatcatcgg tggtggtgac tcagctgccg cagcgattaa
     1801 ccttggccgt gcagacaagt tctcatggat tagtacgggt ggtggagcat caatggaact
     1861 tcttgaaggt aaggttcttc caggacttgc agccttgaca gaaaaataag attttataaa
     1921 caaatcaaag aagagaggga tgaaagttcc tcttttcttt tgcttaaaat aaaaacgctt
     1981 cctctcaact attactcata aaaatcaccg atttatgata aaatggaaat agaaagttga
     2041 gattatgagt tattttaaaa aatataaatt cgataaatcc cagttcaaac ttggtatgcg
     2101 aacctttaaa acaggtattg ctgtttttct agttctcttg atttttggct tttttggctg
     2161 gaaaggtctt caaattggtg ctttgacagc cgtttttagc ctgagggaga gttttgatga
     2221 gagtgttcat tttgggactt cgcgtattct aggaaatagt atcggtggac tctatgcctt
     2281 ggtcttcttc ttattaaata cctttttcca cgaagccttt tgggtgacct tggtagttgt
     2341 tccaatctgc accatgttaa ccattatgac aaatgtagcc atgaataaca aagcaggggt
     2401 tattggtggt gtagcagcta tgttaatcat taccctatca attccaagtg gtgagacaat
     2461 ttcgtacgtg tttgtgcgtg tatcagaaac gtttatggga gtttttgtcg caattatcgt
     2521 aaattacgat attgatcgta ttcgtctctt tttagagaaa aaagaaaaat aatgttacat
     2581 tttataacat tatcaattga cgtttgtctt tttttagact ataatagaca gaaagaagga
     2641 aattgtaaat gaaggaaaaa gaatttcgcc gaaatatggc tgtttttcct atcggcagtg
     2701 ttatgaagtt gaccgatcta tcggcgcgtc agattcgtta ttatgaagat caagagttga
     2761 tcaagcccga tcgaaacgaa ggaaatcgtc gcatgtattc cttgaatgac atggatcgtc
     2821 tgcttgaaat caaagattat atctctgaag gttataatat cgctgccatt aagaaaaaat
     2881 atgctgaacg tgaagcgaaa tccaagaaag cggttagtca gactgaagta cgtcgtgcac
     2941 ttcacaatga actcctccaa caggggcgtt ttgcttcagt acagtcacct tttggtcgcg
     3001 gttaggcaac cgcaagtagt catagattaa ggagaaaact tatgccaatc acagctgcag
     3061 atattcgtcg tgaagtcaag gaaaaaaatg ttacctttat tcgtcttatg ttctcagata
     3121 ttttgggaac catgaaaaac gtcgaaattc ctgctacaga tgaacagtta gataaggtct
     3181 tgtcgaacaa ggttatgttt gatggatctt ctattgaagg ttttgtacgt atcaatgagt
     3241 cggatatgta cttgtacccg gacttggata catggacagt cttcccttgg ggagatgaaa
     3301 atggaagtgt tgcaggtctg atctgtgatg tttatacaac agaaggtgaa ccatttgcgg
     3361 gtgaccctcg tggtaatttg aaacgagctc ttcgtcacat ggaagaagtt ggattcaaat
     3421 ccttcaacct tggtccagag ccagaattct tcctatttaa gttggatgaa aatggggacc
     3481 caacacttga agtgaatgac aagggtggct actttgattt ggcacctact gaccttgcgg
     3541 acaacacacg tcgtgagatt gtgaatgtct tgaccaaaat gggatttgaa gtagaagcga
     3601 gtcaccacga ggttgcggtt ggacagcatg agattgactt taagtacgat gaagttctcc
     3661 gtgcttgtga taagattcaa atctttaaac ttgttgttaa aaccattgct cgcaaacacg
     3721 gactttacgc aacatttatg gcgaagccaa aatttggtat tgctggatca ggtatgcact
     3781 gtaatatgtc cttgtttgat gcagaaggaa ataacgcctt ctttgatcca aatgatccaa
     3841 aaggaatgca gttgtcagaa acagcttacc atttcctagg cggtttgatc aagcatgctt
     3901 acaactatac tgtcatcatg aacccaacag ttaactcata caaacgtttg gttccaggtt
     3961 atgaagcgcc tgtttacatt gcttgggctg gtcgtaaccg ttcgccactt gtgcgcgtac
     4021 ctgcttcacg tggtatggga actcgtcttg agttgcgttc agtggatcca atggcgaacc
     4081 cttacattgc tatggctgtt cttttggaag ttggtttgta tggtattgaa aataaaatcg
     4141 aagcaccagc tcctatcgaa gaaaatatct acatcatgac agcagaagag cgcaaggaag
     4201 ctggtattac agaccttcca tcaactcttc acaacgcttt gaaagctttg acagaagatg
     4261 aagtggttaa agctgctctc ggagatcaca tctacactag cttccttgaa gccaaacgaa
     4321 tcgaatgggc aagttatgca accttcgttt cacaatggga aattgataat tatttagacc
     4381 tttactaata ctaatataga agaaagattg cctgtgggta aacagtcaca cagcagtcta
     4441 agccatcaaa tacctataac ccttaaaata gcgatttcgg tcgctattta tttttcgaaa
     4501 aatcctcttg actcttttgc gaattagatt tatcatcaga cgtgtagaag aaaatcaagg
     4561 agtcactatg gaaaaattca atttcaaaaa caatatcggg caagaaaaca agttacttca
     4621 aatcgaaatc tacaagttta ctaacttttg caagcttcaa aattacacat ctgtaaatat
     4681 tttttcgaaa gatatatttg aagccatagt aaattgagac tagaatagta cactacatct
     4741 gctaaaaatt tctagaaatt aatttaactt tcctaatcga tttgtttaca tcttatttca
     4801 atctactata ttatctcaat aaatgatgat ggcgactgtt ttgtttgtgc ttgtcgattt
     4861 ttgaatcctg atcgagcgga agaatatttc tgccgaggtt gtcaagggga aaattctgaa
     4921 gatattgaat tttatgatga acaattacag gcagaaaagg tggaggcttt gaatattcga
     4981 ttggaagtaa aaaattgaat tatctacaat ctcatcaaca ataaacctat ttcaacccca
     5041 ttatctatag gcgtattttt acgccttttt atatacttga agcacataag aaacattatg
     5101 ggaagtttgc tgatggaagc actcaagaaa ttgatgttcc ttatgatatt cctgatactt
     5161 gggagtgggt gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat
     5221 cctttaggta tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa
     5281 atctacaata tctttcacct gaacaagcgc cttcccgtgc tagaaaatta gtttcgcaga
     5341 atagtgtctt attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac
     5401 ttaaagagta tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa
     5461 catatttgaa atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta
     5521 ctggaacaag ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc
     5581 ccccactatc cgaacaacaa cgaata
//
LOCUS       DAVLZG010000085         5499 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLZG010000085 DAVLZG010000000
VERSION     DAVLZG010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.085"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..875
                     /locus_tag="VYO72_001910"
     CDS             <1..875
                     /locus_tag="VYO72_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1708219.1"
                     /translation="NKAGFELLDLSLRQLNQDCLIALKLLSDPNREQFQHDNRQVDLK
                     ILARHIHRLKKKQSDWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEA
                     GFDKLIEIKRLTASKIQDILSVAPRSIGTTSPAREFEIIEIIKHYKRLIDKAETCVND
                     LMAEFNSVITTVTGIGGRLGAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLA
                     GRMIKRGSPHLRWALIQAAKACARFSPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTL
                     FYILKKSCHLTNKK"
     gene            complement(1074..2963)
                     /locus_tag="VYO72_001911"
     CDS             complement(1074..2963)
                     /locus_tag="VYO72_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1708220.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3101..4666
                     /locus_tag="VYO72_001912"
     CDS             3101..4666
                     /locus_tag="VYO72_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1708221.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4666..5430
                     /locus_tag="VYO72_001913"
     CDS             4666..5430
                     /locus_tag="VYO72_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1708222.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
BASE COUNT         1701 a         1251 c         1027 g         1520 t
ORIGIN      
        1 ataataaagc tggttttgaa ctcttagatc tgtctcttcg acagctcaac caagactgtc
       61 tcatcgctct taaacttctt tctgacccca atcgtgaaca atttcaacac gataatcggc
      121 aagtagacct aaaaatactg gctagacata ttcatcgtct caagaaaaaa cagtctgatt
      181 ggaaagtaca atacactcgt tgtcttgata tcatctttcc tgagttggat aaaatcgttg
      241 gaaagcattc agaatatacc taccaactct tgacgcgcta ccctaatcct cagaaaagga
      301 ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct aaaattcagg
      361 atatcctctc agtcgcacct cgttctatcg gaacaacatc tcctgctcgt gaattcgaaa
      421 tcatcgaaat catcaaacat tacaagaggc tcattgacaa ggcggaaaca tgtgtcaatg
      481 acttgatggc tgagttcaac tcagtcatca cgacggttac tgggattggg ggtcgtttag
      541 gggcggtcat tttagccgag attcgaaata ttcatgcctt tgataatcct gctcaattac
      601 aagctttcgc tggactggat tcttctattt atcagtcagg tcagattgat ttagctggaa
      661 gaatgatcaa acggggttcc cctcatctgc ggtgggcact catacaagct gccaaagcat
      721 gcgctcgctt ttcacctgct tttaaggcct atcttaagac taagttagaa caaggaaaac
      781 attacaatgt agccatcatc caccttgcaa aaaaacttat ccgaaccctg ttttatatcc
      841 taaaaaagag ctgccatttg acgaacaaaa agtgatgtaa tttctgaaat taacacagga
      901 ttacctttga aaaaatggac tttttcaagg gctttttgcc gtgctctaaa atcatcgcca
      961 aatcatcaaa ttgaaataag aaatagttta gataaaacta ttgacttttc ttatagtttg
     1021 tctttcttct atcttccatt atatcatact ttttcagtct atggtagctc tctttaaaag
     1081 gctccgatac tgccgccacc tccgcctcca gagaagccac cgccagaact tccacttcca
     1141 gaagatacgg agtaggtact tgctgtattt gcgacactag cataatggct catttgcgcg
     1201 cttgaatgat aaaacatact gtgccagcca taagctacat agagattgat atctggattt
     1261 tcaacttgaa tctgatgaac cttcatcaaa tgactaacct tgtccgcata gccaaataag
     1321 gttgcataga ccaagagacg attccaaaca acaatacttt ccaattcagc cttatccagt
     1381 cgtgcaatct cacgtaacat attttcaaaa ctggtccaga gatagtagac ctcagctccc
     1441 gcttcattta gaacaccatc acgattatct agtcgaagct tccaataata gaaaacagac
     1501 aaaactaacc ctagaaaacc aagtattggc aaagggaggt aaagatagcc atgaacgtct
     1561 aaactgtaca agaacaaacc aaatccgata aataggggca agatagtcaa gacacccata
     1621 cccacttgca aagtcttttc caaaccagtt aaaggacgat agtaatctgg gagcccccag
     1681 aaggaaactc gttttctcac tccttcttgc atctggttca atacctcttc aaaagaagat
     1741 ttgagttgaa gccctcttgc ttgaatccgt ttttcatcag aaactttggc tctacgataa
     1801 agactatcag ataccttgta atccgcaaac aaattggaaa gagtggcttc ttttttgcct
     1861 gaaaaggcta gatttagaca gtctctctca aatcttgaca aaccatcttc tttcaccaat
     1921 ctcaagccaa ctgcatctcc ttctgaaata atagagacat tcccacggtc tatcacatct
     1981 agcaaggtag cttgaataag ttgatcaaag gtgaattttc cagctccctt gaccaaggga
     2041 ctcacttcct ccaaggaggt cgagtagact gcttctgata aaaccatagg ctctaattcc
     2101 attggtggtt catagagacg atgatttttg gcatatttga ctgaaggagt ggtctttctt
     2161 ctataaataa aatagaagca gacactcaat aacaaggaga tggaaaggat cgaagggagg
     2221 acccaagtaa cgagttgttt actctgatct ttttctctaa caatcgagtc ttctatctta
     2281 ttaaactctt ctaaacgatt ccctttcaag ccctgatccc tagcgctagc aaaatcggtc
     2341 cgagaccaat aggcatgcaa ctcaactcca cgcttagccg gaagattgtc taaacggata
     2401 gtataatcaa ggttactctt ttcaatcgtt ccctctctaa aaagtttccc tgtatggaaa
     2461 aagagttttt cagccccctt gtctcccctt acatgaaatt caaacttttc aatagactct
     2521 gaactatctg tcagaggttg ccaatttaat tcagcgatat catcataaag gaaaagtaaa
     2581 ttttttaagt tccagacgag gtcaacttca actatgtcgc cctcctgacc tggattatag
     2641 actctcacag tataaccatc cgcttcttct gttacttcgc tagtcacatc tgctagttct
     2701 gcaccgtttt tcgcagcctg aacctttgga tgagggtcaa tgtcaaaccc gctaggcatc
     2761 ttaccagcac gtccaagtcc cacgatttgg cccttaaagt cctcctcaaa ctggtaaact
     2821 atcttctgtc taaactctgc cgtattatct gcatgaatat acaaatcccc ttgataagag
     2881 tttatcttga aatcaatggc aaaaacagag agtggaagaa ggcaaaacaa gcctaacacc
     2941 agtaagaaaa aagttttttt catcaactaa gccccctttt tatctttctt atcattatag
     3001 cattttttcg taagtaaagg cttacttatg ttgaaaaatt acgcattttt cgataaaata
     3061 ggagacagtt attttttaat agatcagaat aggagaaatc atgagaaaaa tatacttatc
     3121 tattttcaca agtctcttgc tgatgctagg acttgtcaat gttgctcaag ccgatgaata
     3181 tttacgcatc gggatggaag cagcatatgc tccctttaac tggacccagg atgatgatag
     3241 caacggagct gtcaaaatcg atgggaccaa tcagtatgcc aacggatacg atgttcaaat
     3301 cgccaagaaa atcgctaagg acttaggtaa agaacctttg gttgttaaaa ccaagtggga
     3361 aggtctagtc cctgccctta cttctggtaa gattgacatg attatcgcag gtatgagtcc
     3421 aactgcagaa cgcaaacaag aaattgcctt ttcgagcagt tactacacta gcgaaccagt
     3481 tttgcttgtc aaaaaagatt ctgcctacgc aagtgctaaa tctttggatg actttaacgg
     3541 tgcaaaaatc acttctcaac aaggggtcta cctctacgac ttgattgcac aaatcccagg
     3601 tgctaaaaaa gaaacagcca tgggagactt cgctcaaatg cgacaagctc ttgaggctgg
     3661 tgtcattgat gcttatgttt ctgaacgtcc agaagcactg actgctgaag ctgcgaactc
     3721 taagttcaag atgattcaag tagaacctgg tttcaaaact ggggaagaag atacagctat
     3781 cgctatcggg cttcgtaaaa atgacaatcg tattagccaa atcaatgcca gcattgaaac
     3841 catttcaaag gacgaccaag ttgccctgat ggatcgtatg atcaaggaac aacctgccga
     3901 agctacaaca actgaagaga ctagcagtag tttctttagc caagtcgcta aaattctttc
     3961 tgaaaactgg caacaactct tgcgtggtgc tggtatcact cttttaatct ctatcgtcgg
     4021 aaccatcata ggtctcatta ttggacttgc cattggtgtc ttccgtactg ctcctctctc
     4081 tgaaaacaaa gccatttatg gccttcaaaa actagtcggc tgggttctca atgtctacat
     4141 tgaaattttc cgtggtacgc caatgattgt tcaatcgatg gttatctact atggaactgc
     4201 ccaagctttc gggatcaacc ttgaccgtac actggctgct atcttcatcg tttcaatcaa
     4261 taccggtgcc tacatgactg aaatcgtccg tggtggtatc ctagcagttg acaagggaca
     4321 atttgaagct gcgactgctc ttggtatgac ccataaccag accatgcgta agattgtcct
     4381 acctcaggta gtccgtaaca tcctacctgc aactggtaat gaatttgtca tcaatatcaa
     4441 agatacatct gtattgaacg ttatctctgt tgtcgaactt tatttctcag gaaataccgt
     4501 ggcaacacaa acctatcaat acttccagac atttacaatc atcgccgtga tttactttgt
     4561 cctcaccttc accgtaacac gtatcctacg ctttatcgag cgcagaatgg acatggatac
     4621 ctacactaca ggtgctaacc aaatgcaaac ggaggatttg aaataatgac acaagcaatc
     4681 cttgaaatta aacacctcaa aaaatcctat ggacaaaacg aagtgctaaa agacatttct
     4741 ctcactgtcc acaagggaga agttatttct atcatcggaa gctctggaag tgggaaatca
     4801 accttcctac gctccattaa cctacttgaa acgccaactg atggacaaat cctttatcat
     4861 ggacaaaacg tcctcgaaaa aggctatgac ctcacgcaat accgtgaaaa gttagggatg
     4921 gttttccaat cctttaacct ctttgaaaat ctcaacgttc ttgaaaacac aatcgtcgct
     4981 cagacaactg tccttaaacg cgaacgcaca gaagctgaag aaattgccaa agaaaacctg
     5041 gaaaaggtcg gcatgggaga acgctactgg caagcgagac ccaaacaact ctcaggtggt
     5101 caaaaacaac gtgtggccat cgctcgtgcc ctttcaatga atcctgacgc cattctcttt
     5161 gatgaaccaa catcagctct cgatccagaa atggttggag aggtcctcaa aatcatgcaa
     5221 gatctggctc aggaaggctt gaccatgatt gtcgtaaccc atgaaatgga atttgcccgt
     5281 gatgtctctc accgtgttat ctttatggat aagggtgtga ttgctgaaga aggtaaacca
     5341 gaagacctct tcactaatcc taaagaagac cgtacaaaag aatttcttca acgttatctc
     5401 atactcaatg aaaatcaaag agcaaactag gcagctagcc gcaggttgct caaaacactg
     5461 ttttgaggtt gcagatagag ctgacgtggt ttgaagaga
//
LOCUS       DAVLZG010000086         5212 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLZG010000086 DAVLZG010000000
VERSION     DAVLZG010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.086"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(360..1088)
                     /locus_tag="VYO72_001914"
     CDS             complement(360..1088)
                     /locus_tag="VYO72_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1708223.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1246..2655
                     /locus_tag="VYO72_001915"
     CDS             1246..2655
                     /locus_tag="VYO72_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1708224.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2673..3968
                     /locus_tag="VYO72_001916"
     CDS             2673..3968
                     /locus_tag="VYO72_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1708225.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLALVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3973..4281
                     /locus_tag="VYO72_001917"
     CDS             3973..4281
                     /locus_tag="VYO72_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1708226.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4278..4586
                     /locus_tag="VYO72_001918"
     CDS             4278..4586
                     /locus_tag="VYO72_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1708227.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1755 a          879 c          948 g         1630 t
ORIGIN      
        1 tgggagattg aaattcattt ctagcaattt tttagaagtc acagtctact attctaacct
       61 cagtatacta tatgtgttac aagaaaagac tcaaaaactt ctcgtcagtg taagaatgtt
      121 tgaaacacta tttaaaacta aataactata agaagtagat caggtgaaca atttcagtac
      181 ctactctata agctatacga agatattttt caacatgatg gataaaacga tcactctttt
      241 aaagctatct tatttagaaa agagaaacca tttaagcata gatgggacct tcttgccctg
      301 ttttaaattt ttcttaaact agagtctgta aaagattggc ttcattttca cattttctcc
      361 taggaggaat gtcgtaatgc aaaagaatta aattcaaata aatcatagcg atgacgacta
      421 atcgagtact caaacggagt tccgttatcc aaataagcca cttgttctac ttcaaatacc
      481 ggttccgttg gaaggagctg caagtaatgt tgctcatttt ctgaactaga agaagctcgc
      541 aagatttttg tagcactggc aatatgcaat cctaactttc cttcaatgta attgtaaatc
      601 gatttttgta aaatatcttc agtaatacct ggaataacat cggtactcat ataagtttgt
      661 tccagaacat aaggtttacc gtcaataata cgcagacggt aaatattata aactggactc
      721 tgcaaagcga cctgtagttt ttctgctaaa aattcatttg caaattctaa tttgaagtga
      781 ataatcctcg agtcaattgt agaatgagca tcttcagata tttttgtcag tccccggata
      841 tctctttctg gaacgattaa ttttcttttt gagctgccac gagagagaac aaaggttccc
      901 tgcccacgtt ttctaaaaat taagccctca gaaactaaca agtctaaagc ttttttgatc
      961 gtcattcgac tacaggcaaa ctgtttagct aatgtcattt catcaggcaa ttgttcgttc
     1021 atggtatatt tattacaaag aatcttttca cgaatctcat tgtaaataaa taaatatttt
     1081 gtactcattt aatctggttc tctctataat attctaatag tagtataaca aagttcaaga
     1141 aatgaggcaa acacaagaca tgtatcaaca atttttaaaa atgtctagac aaattttaaa
     1201 attatgctat actttatgta tagaataata gaaaggaggt tgagcatgaa aaaaaagtta
     1261 gtatttccta atctgttttg gtggggagct gcttctagcg gacctcagac agaaggtcaa
     1321 tatggaaaag tacatgaaaa tgtgatggac tactggttca aaacgcatcc agaagatttt
     1381 ttcgataatg tcggacctct tgtagccagt aacttttttc atacttacac cgaagatttc
     1441 cacttgatga aggaaattgg agttaattct ttccgcactt ccatccaatg gagtcgactc
     1501 atcaagaatt tagagacagg tgagcctgat ccaaaaggta ttgctttcta caatgccatc
     1561 attgaagaag ctaaaaagaa ccagatggat cttgtgatga atttacatca ttttgattta
     1621 ccagtggaac ttcttcaaaa atacggtggt tgggaaagca aacatgtagt ggagttattc
     1681 gtgaagtttg ccaagactgc tttcacatgc tttggagata aggttcatta ctggacaact
     1741 ttcaatgagc caatggtcat tccagaagca ggatacttat atgctttcca ttatccaaat
     1801 ctaaaaggaa agggaaaaga ggccgtacaa gtcatctata atctaaacct tgctagtgca
     1861 aaagtgattc aactatatcg ctcattagga cttgatggaa agattgggat tattttaaac
     1921 ttgacacctg cttatccaag aagtaattct ccagaagact tagaagcaag tcgatttaca
     1981 gaagacttct ttaacaaagt cttcttgaat ccagctgtta aaggaacttt cccagaaaga
     2041 ttggtaaaac agctagagag agatggcgtg ttatggagtc ataccgaaaa agagcttcaa
     2101 ctgatgaaat caaatacggt tgattttctt ggagtaaact actaccatcc aaaacgtgtt
     2161 caagcacaag caaatcctga ggaatatcag acgccctgga tgccagacca atacttcaaa
     2221 gagtatgaat ggccggagcg tcgcatgaat ccatatcgtg gttgggaaat ttttccgaaa
     2281 gccatttatg atattgctat gattgtgaag gaagaatatg ataatattcc atggtttatc
     2341 agtgaaaacg gaatgggtgt tgaaaacgaa gcacggttta tcgatgaaaa tggagttatc
     2401 gatgacgtgt atcgtattga attttatgaa gaacatttaa gatggctaca taaagccatt
     2461 gaagagggaa gtcactgttt tggataccac gcttggaccg catttgattg ctggtcttgg
     2521 aataatgcat ataagaatcg ttacggattt atctccgttg atttagaaac gcaaaagaga
     2581 accatcaaga gctcaggaag atggtatcgc aaagtaagtg acaataacgg ttttgaagta
     2641 gaaattgagg agtaaagaga ggagatattc agatgaaaaa ctcaaaattt atagatcaat
     2701 ttgccacctt tgctggtaaa ctagggaacc aaattcattt aaaaacccta agagatgcat
     2761 tcgtaacagt aatgccatta tatattttgg caggtttaat cgttcttttg aacaacacgg
     2821 tatttaagtg gattttccaa ggggatacat taacaaaatt ccaatattgg ggaataacaa
     2881 ttgcaaacgg tactttaagt atttcaggta tgattattgc tgtaatggtt ggttatttct
     2941 tagctaaaaa cagagatttc gaaaacccgt tagcagcatc aatgctagca ttagtttctt
     3001 taattgtgat gatgccaaat acagtttctg tagttcctga cggagcaaaa gatgctgtaa
     3061 acatttcagg tgttctttca ttcaacaaca caggtacagg cgcaatgttc gccggggtta
     3121 tcgtagcgat tattgcaaca gaattattca ttgaattatc aaacgttaaa gctttacaaa
     3181 tgaaccttgg tgaaaatatt ccaccagctg ttagtagatc atttagcgta ttacttccag
     3241 tcatgaccgt catctcctta tttggggttg tttcagcatt attattcaat ataactggaa
     3301 tgaacttaat ctcaatcatt acaatcttta ttcaagaacc aattcgtcat attggtacaa
     3361 gcttaatcgg ggtcattatt atttactctt taggaaatat gttatggcta tttggtattc
     3421 accaagcagt tatttacagt gccatcctag aaccattact attaattaac attactgaaa
     3481 acatcactgc agcaaataat ggacaagcca ttccacacat catcaaccta tcacaaatac
     3541 aaacattcgc tttaatgggt ggtagtggat ctacattatg tttattaata gcaacattct
     3601 tagtgagtcg caatgctgtc tctaaaaacg tggctaaatt atcttttgga cctggtatct
     3661 tcaatatcaa tgaaccagta ttattcggtt acccaatcgt ttataacatt tcattagcta
     3721 ttccatttat cacagttcca gtccttggta ttttaatcag ctacttagca acagttacag
     3781 gattcatgag tcctgcattt atacaagttc cttggactac accagtattc ttaaatgcat
     3841 ggttagcaac agcaggggac gtgagagcag ttctagttca attcatcatc tttgcacttg
     3901 gagttcttct atacattcca tttatcaaag ttaatgacaa agttgttgaa caagaaatgg
     3961 aaggttaaga ttatgaaaca aattttatta gtatgtaatg cgggaatgtc gacaagtatg
     4021 cttgttaaaa aaatgcaaca aagtgcgact gaacgtggga ttgaaatctc tatccaagca
     4081 aaatcaatga cagaagctaa aaagaatatc catgaagcag atgtcattct aattgggcca
     4141 caaattcgtt atgagttact tgctgtgaaa gaaattgcag gaaatatccc tgtagatacc
     4201 attgatatgc gggattacgg aatgatgaat ggagcaaaag ttctggaaca agcacttgca
     4261 tggataggag aaataagatg acagaagaaa tggaatatat ctgttttcag ctcattgcca
     4321 atagtggagc agccaaatca tcctttattg aagccatcca actagctaag gcaggaaatt
     4381 taaaagaagc gaaaattaaa gttgaagaag cggaagactc cttagtagaa gcgcacaaga
     4441 ttcactctaa tctcatacaa aaagaagcta ctggagaaaa aataggattc tccttgctat
     4501 ttatgcatgc agaagaccaa atggcttcaa cagagattat tcagttgcta tctaaagaat
     4561 tcatcgatct ctatcaaaat aaataggaac actgtcattc ccatctgtct ttattaatga
     4621 cgactacatt gtaggaacct ccaaaagttg gacaaaatga ttgaaaggat tggatcctgc
     4681 attacacaag atccaatcct tttcttttac tctagttttt ataatatgtt gaatctagaa
     4741 tagtccactg tagtttctaa aaaattgctg gaaatggatg ttaagctcca atttatttgt
     4801 ttatatctta tttcagttta ctatactagc ttattattct agtgaaaaat tgaatgagcc
     4861 actatttatt taatatgtat gatgagggaa tgactcaaaa acttcttgtc gatataagaa
     4921 tatctgagat agtattttaa aacgaaagga ctataaaagc tcatttcctt cgcacttatt
     4981 ttatagagat ctatcattat actctttaga aatcaaaaag caacacacct tgtcatcgtt
     5041 ttatcgtaaa tctgttaatg agggggctag tcttatctgc aatctcaaat cagtgttttg
     5101 agctgaatgg cactcgtttt ctagtttgct ctttgatttt aattgggcct tagtaaatac
     5161 tactcttaaa ttaaactata gtgaattgaa ataagatgtg aacaactcta tc
//
LOCUS       DAVLZG010000087         4993 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLZG010000087 DAVLZG010000000
VERSION     DAVLZG010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.087"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(554..1546)
                     /locus_tag="VYO72_001919"
     CDS             complement(554..1546)
                     /locus_tag="VYO72_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1708228.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1706..3460
                     /locus_tag="VYO72_001920"
     CDS             1706..3460
                     /locus_tag="VYO72_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708229.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3444..>4993
                     /locus_tag="VYO72_001921"
     CDS             3444..>4993
                     /locus_tag="VYO72_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708230.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKT"
BASE COUNT         1793 a          711 c          835 g         1654 t
ORIGIN      
        1 atcgaaaaat ggttaagtaa aagtcaacag ttactatagt ttgcaaatta tttacagaaa
       61 gaacaaaaat gctctgaaac actgatttca aagcattttt ttgttagttt aaaattactc
      121 ccattcttct tttccaaacg tacaatatat ccaaaaccat tcaaaatact agattctatt
      181 ttttataata tcactaaatc cacctaatta taggacgttt tcagattttt agtcccgtcc
      241 cagtcccagt accggagaaa tattgtttta atataatatc tctttttgtc ttctaagctc
      301 ttaaaagcaa aagaacaagt aaagagtcaa gacaaggata aaaagtccat attagggcaa
      361 ataaaaagct ttaagacaga tgacaaatct aagtcaaata agaaagacca tagcaaaggt
      421 gcagagagat aaatattggc ggtcttcgga ctgcctttat ttttttatcc atttttcaaa
      481 tcaaatttat tcagactata tatgcacata tacacttaaa ttcatataaa aacatggctt
      541 gtaaaaaatt actttaatca caataatcgc atttaaaatt gtgatgtttg caagctaaat
      601 tacggacttc acttggaagt tttcccttgt atcttttata atagatagaa aatttgctgg
      661 cagatgaata tccaacagat tctgctatct cttttatagg tagttcagtg tttaaaagaa
      721 gagtttcagc tacattcatt ctttttcttt gagtgtactc tgtaatgctt tgacaatatt
      781 tttccttaaa taaatttttt aatttagtac cactcatttt agatattttt tcaagcgtgc
      841 cttgatttac attcgttgca aaatgatcat ctaagaatct tgctacatct tcaagtgctt
      901 tatcatcatc aatttcaatt ttatattttt ttctatttaa gtatgtgtca attactatac
      961 ttatccattc atttgccttt gctttaaaga aaaaatcagc ggcaggagcg tccatcttac
     1021 aatttaatat ttccattgcc actctttcta aggcctttgt aagtattatt tgattcggtt
     1081 gaagcaaggt tgaataaaaa gattctggat taatgttaat agatgctaaa tgtttttcta
     1141 ttagctcttt tttaaaacca atggaaacag caagataaca acaattctcg tgtaataaaa
     1201 aaacaaaatc atcttttata ttatcaaaat caaaagtaca tagagagttt gcggtaatag
     1261 tttgatacgg attaaacttt tctccgtttg cactgacaat gtaacttgaa taaattgaaa
     1321 catagtctga catactataa gtgctatttt gaactacttc ctctttgata taaaaatcat
     1381 gtatatcgat aatgaagctg cctccttcat aaaaccaata taggccttct gcataagttg
     1441 aattctcttt tttccaacaa aatgtatgac ctgcacttga atacttctca ttgtttttac
     1501 attcatctac tttcatataa tcttttacaa aatcataata tgacataaca cactatccct
     1561 tttagacaat attccaatta gccttattaa ttcaaaacta ttgtattagt aattataaca
     1621 gatgtataat agaaaagcaa tgatagatat tatcaattaa gcgaatttat atctaaaagg
     1681 gatattaaag aaaggagata tgcttatgaa gatttacaaa aaactatttg cttatgtcca
     1741 agataagaaa tatcttgggg ttttggccat aattttttct gctatatctg ctctacttac
     1801 agtatatgga tattatttaa tctacaaatt tctagataag ttaataatta attcaaattt
     1861 atccggtgca gagagtatag cattaaaatc tgttattaca ctaacaagtg gagcgatatt
     1921 ttattttgtc tcaggaatgt tttcacatat cttgggattc aggcttgaaa caaatttaag
     1981 aaaaagggga atcgatggtc tggaaaaagc aagttttagg ttctttgact taaatccatc
     2041 tggtcaaata agaaagatca tagatgataa tgcagcacaa actcatcagg tggtagcaca
     2101 catgattccc gatagttctc aggcaataat cacacccgta cttgtacttg cacttggctt
     2161 tatagtaagt ataagagttg gcataatttt gcttgctctt actataattg gtggcttaat
     2221 tttaggggcg atgatgggcg agcaagaatt tatgaagata taccaagaat ccctatctaa
     2281 actaagtgct gaaactgttg agtacgtgag aggaatgcaa gttgtaaaaa tatttaaagc
     2341 aaatgtagag tcatttaaaa gcttttacaa ggctataaaa gattactcaa agtatgctta
     2401 tgattattcc ctatcttgta aaaggcctta tgttttgtat caatggttat tttttggact
     2461 gattgcaatt ttaattattc ctatagttta ttttatgact agcttagcta gcgcaaaggt
     2521 gattttactt gagcttatca tgattttatt tttatcagga gttctctttg tttcattcat
     2581 gagaatgatg tggtactcca tgtatatttc tcaaggaaat tatgcagtag atactttaga
     2641 ggcgctttac gaagatatgc aaaaagacaa attagtgcat ggtaatgtca ataattttaa
     2701 aaactataat atagaatttg agaatgttag ctttgcttat aatgataaag ctgtcattga
     2761 aaatttatcc tttaatttag aagaaggaaa gtcctacgca cttgtcggtt catctggatc
     2821 aggcaaatca acagtagcaa aacttatatc aggtttttac aatgttaatg aaggaagcat
     2881 aaagataggc gggatagcaa taagtgaata ttctgacgaa gccttaatta aagccatttc
     2941 ctttgttttt caagattcaa aattattcaa gaagagcatt tatgataatg tagctttagc
     3001 taataaagat gcgacgaaag atgacgttat gagagcctta aaattagcag gatgcgattt
     3061 aatattagac aaattcccag aaagagaaaa tacaatcata ggctcaaaag gtgtttattt
     3121 atccggtgga gaaaaacaaa gaattgcaat tgctagagca attttaaagg attccaaaat
     3181 tattattatg gatgaagcat cagcatctat tgacccagat aacgagtttg aattgcaaaa
     3241 agcttttaaa aatcttatga aggataaaac agttatcatg attgcacaca ggctatctac
     3301 aattaaagac cttgatgaaa ttattgtcat ggatagtgga aaaattatag aaagagggtc
     3361 tgacaaagaa ttaatgtcaa aagatacaag gtataagagc ctgcaagaga tgtttaacag
     3421 tgcgaatgaa tggagggttt caaatgaaag agttttataa aaaaagattt gctcttacag
     3481 atggaggagc aagaaattta agtaaagcaa cactggcttc atttttcgtt tattgtataa
     3541 acatgcttcc tgccatatta cttatgattt ttgctcagga agttttggaa aatatgggca
     3601 aaagcaatgg cttttatata gtattctcag ttttgacttt gatagcaatg tatattttgc
     3661 tttctatcga atacgataaa ttatataaca caacctatca agaaagtgca gatttaagaa
     3721 taaggacagc ggagaattta tcaaaattac ctctatctta cttttctaaa catgacattt
     3781 ccgacatttc acaaacaatc atggctgata ttgaaggcat agagcatgca atgagccact
     3841 caataccaaa ggtgggcggc atggtactgt ttttcccatt aatatctgta atgatgctag
     3901 cgggcaatgt caagatgggt ttagctgtaa ttattccatc tattttaagc tttatattta
     3961 tacctttatc taaaaaatat caggttaatg gacagaatag atattatgat gtcttaagaa
     4021 aaaactcaga aagctttcaa gaaaatatcg aaatgcaaat ggagattaaa gcatataatt
     4081 tatcgaagga tattaaagat gacttatata aaaaaatgga agatagtgag agagtacact
     4141 taaaggcgga agtaactaca attttaactt tgtctatatc ttcaatattt agctttatat
     4201 ctcttgctgt tgtgatattt gtcggcgtaa atctaattat taataaagag ataaattctc
     4261 tctaccttat aggatattta ctagctgcta tgaagataaa agactcttta gatgcatcta
     4321 aagagggctt gatggaaata ttttatttat cgcccaaaat agaaagatta aaagaaattc
     4381 aaaatcaaga tttacaagaa ggcgatgact atagcttaaa aaaatttgat attgatctaa
     4441 aagatgttga gtttgcctac aataaagacg caaaagtttt aaatggtgta agttttaaag
     4501 ctaagcaggg agaggtcact gctttggtag gtgcaagtgg ctgcggtaaa acaactatct
     4561 tgaaacttat atcaagactt tatgattatg acaagggaca aatcttaatc gatggcaaag
     4621 atataaaaga aatatcaaca gaatctcttt ttgataaggt ctctatagtt ttccaagatg
     4681 tggttctctt taatcaaagc gttatggaaa atattagaat cggaaagcaa gatgcaagtg
     4741 acgaagaggt taaaagagca gcaaaacttg caaattgcac agattttata gaaaaaatgg
     4801 ataaaggttt cgatacagtt attggtgaga acggagctga gctatcagga ggagaaagac
     4861 aaagattatc aatagccaga gccttcttaa aagatgcgcc gatattgatc ttagatgaga
     4921 taacagcaag ccttgatgtt aacaacgaga aaaagattca agagtcttta aataatttag
     4981 ttaaagataa aac
//
LOCUS       DAVLZG010000088         4869 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLZG010000088 DAVLZG010000000
VERSION     DAVLZG010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.088"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(298..1521)
                     /locus_tag="VYO72_001922"
     CDS             complement(298..1521)
                     /locus_tag="VYO72_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1708231.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISEILPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQGLSVKSFCQHLLQS
                     SKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFELS
                     ALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGVL
                     SPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLLF
                     LLVAFVMLLNIRESI"
     gene            complement(1593..2258)
                     /locus_tag="VYO72_001923"
     CDS             complement(1593..2258)
                     /locus_tag="VYO72_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1708232.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2270..2947)
                     /locus_tag="VYO72_001924"
     CDS             complement(2270..2947)
                     /locus_tag="VYO72_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1708233.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            complement(2969..3202)
                     /locus_tag="VYO72_001925"
     CDS             complement(2969..3202)
                     /locus_tag="VYO72_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708234.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            complement(3488..4351)
                     /locus_tag="VYO72_001926"
     CDS             complement(3488..4351)
                     /locus_tag="VYO72_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1708235.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRFGRKVVDRFAHQDIVGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIVLFE
                     LRLQQYKKLID"
BASE COUNT         1716 a          947 c          839 g         1367 t
ORIGIN      
        1 aaccatacct acggcaaagt gaagctgacg tggtttgaag agagtttcga agagtataag
       61 tagactgaaa agaatccagc cacagcatgg actattatat agcagattga aataagatga
      121 gaacaaatcg attgggaaag taaaattaat ttctataaat tttttagcaa ttgtttcgta
      181 ctattttaga ttcagtctat tataacacat tcagaaaaga gaaaaaagtc tgttgatttt
      241 gaccatcata aaaagactgg caatccagtc tcaaacatat attatagaaa ttctccacta
      301 aatactttca cgaatattca gaagcataac aaaggcaact agaagaaata gcaataaaac
      361 aaagctaact gccagagttc caaagctagt agcaatggtt accaaagcta ttgtaaataa
      421 gctaggtaaa acaaccgtaa tggcaccgat agaggattga actgctccca ttgactcctc
      481 aggtatttgt ttaaaaacga gttcttgcaa tctaggagag agaacacctg cgaaaaaggc
      541 atccaaggta ctaaagatga gaatccagtc aaaacgaact gtggcaaatc ctactagaag
      601 aagcaactgg atgacaagtg aggcatagag agctgttttt atggaaatgg tatgttgcag
      661 atagccactt acaaggcttc cgacaatcag ggctgacagt tcaaaagtgg atagcaaggc
      721 aagagattga cctgtttgta aattcaaaaa gggttgattc ctcaaaaata gagtagagac
      781 aggaactgta acatttatca ctgcttgact agtagagata ataaacaaaa ccaagagcac
      841 cttattcata ttccatatca atttcgatga ttggagcaaa tgctggcaaa aggattttac
      901 agagagtcct tgatagttaa tcgttttttc tactttcaag aggtcagttt ttatgaaaag
      961 gatacctaaa aatgcgatta aaaaggtaag agcgttcagc aaggaaatga actggatgga
     1021 gagaatccct agcaagactc ctcctagaat attactgatt gttttcacta aactaacagt
     1081 tgactgttta aatccaatag cttctgccag atggtcttgc ccaataattc taatgaaaat
     1141 cggagtgagc atggctcctg aaaagtaact caatgtgtca gacaagaggt taatcagaca
     1201 aataaatgct actagcaaca aggagaaaga ctgccctgaa agtgataaag aaacgataga
     1261 gtaaagcaaa aattttgcaa aactaatgac tgtgtatttc aagacacgat gatgttgaaa
     1321 atctgccaaa actcccagaa agatttgtaa aatttgggga aggatttctg aaatcgtaat
     1381 gagtaaaatc gccaaaggtg caaaagacgc atctgccaca taattcagaa aggccagata
     1441 aaaaatcgta tccccaagcg ttgaaatcca ctggttgata gttaattgcc taaaatctct
     1501 attttgaaga aatactttca tcacaactcc ttcttaagtt caaatgggaa tctttcccca
     1561 gaaatagacc gcgatactac taacaaccaa aattacagta acatcaaaag ctgaccaatg
     1621 ccgttgtaga ctatatgcag cccaataggc caataaatgg actttgtcat tctaaataag
     1681 actgcaaata taagtccgcc acccatatag acgaaaaagt ctgtcaagac ccaaccgtga
     1741 ttactaatgt gcgagacccc aaataaaata gcagaaccaa gtacatctag cccccatttc
     1801 tttccttttt ccagagctgt catcaccaat ccccgatgga ttatctcttc aaaaatggga
     1861 cctgcaatca caggatagaa aaaatacatc aaaaatgctg tagcccctgt aaaagtcgga
     1921 gcagcatgtt gataagaaat ttcatttcga gtaggtggga aaagaaaaaa ggtaacgaaa
     1981 ttccaaacaa caaaagcaag cagagctagg aaggaataga aaagatagga tcctttaaac
     2041 tttctactat tgattttctg ccatttcccc gaccaaatca tagcaataag agcaaataaa
     2101 accacaagaa aattcaacat catatccgac agataatagg caaagtcaga tagcccagta
     2161 acaaggtcgc tgcgtaaaac tagaacactg aacttctggt cagcaataac tagtagaaaa
     2221 actataataa agtagcggtg tgagattatc tttttcatat atcacctttc taatatccaa
     2281 ataccaataa agtaacaatg agtaagaaac tattccatga agcatgcaga gctatagccc
     2341 aatagatgga tcgggtgtag cgaaacatca tacaaaatat caagcccatt ccaaaatact
     2401 ttatgaaatc tgtcgttatc caaccatact gcaaaacatg catagcgcca aatatggcag
     2461 cggaaacaag aacatcaaga tagtatctct taactttaga taaacttgtc atcaaaagac
     2521 cacgacaaac aacctcttct gatacaggtg cgataatact agtataaagt attcgcgtaa
     2581 caaaatagct aattcctgtt aaattggtgg ctacttctac gactgtactt ccattctggg
     2641 tacgaggaaa gatataggtt gttagatttg cccacacgaa caataagaaa aaagaaagaa
     2701 ggaaaacacc caggtaagac caacgaaact ggaaacgacc acactctttc caatgttcac
     2761 ttttgacaaa agcaattgta gctatagttc ccagaataag taccaataaa acttggaaca
     2821 catagtacat attatcagac aaagcaacca taaaatctaa gtctgatgtg acattaaaaa
     2881 tgaggtaata agtcaaaatc aacaagccag ttgctaggtg aaatttcact tctttcattt
     2941 tcttcatcct attatctcct ataagagcct atcttctacg gcggccaaac aatccatctg
     3001 ctaaatctat agtccaatca aaagctccac gattaggact catcccttga ttgccccaac
     3061 cagggtaaat tcctgggacg ccccaaccag atataccact tcttccacca cctcccatag
     3121 aatttacgag gttgcctcct ctaacatctt gcaactcagc ttctgtcaat tccattgttt
     3181 ctgcaaattg taaatttaac atcttttaca ctccttcaat tatcttcatt tgtaaaccac
     3241 ttctgcgacc taggatttgc ttcaagtgct ttacaagtac agtataacac gaaaattggc
     3301 ttattttaga aaatcgcata tttgatattt tttcttatag aaatttcaga tttgcgattt
     3361 tggtgaattt gattacttct ctggtataat aaagttacta ctaatgagga gtggagaaat
     3421 atgaagaaac aaattttaac attattgaaa atcgttgctg agattattat tattttgcca
     3481 tttctaacta atcgataagc tttttgtatt gctgcaaacg caattcaaaa aggactatta
     3541 attgtggatt ttctaatact tgcagagatt ggataaagtg ttcaatctct ttttggttgc
     3601 ttcccttggt ttgaagaaaa atactcattt tctttaaaaa ctgccacaac actttctcaa
     3661 aaacatcata cggacggagc atactctcca actcggcttc aaagattggg atgtaagaga
     3721 aaagtttgcg ctccatgagc tctgatataa tattcagaaa gccacttttc atatacagtc
     3781 tattatgtac caactcttta aattccttag atttttcaag caaagaggtt gataaaaaaa
     3841 tcaaatcttg gttgctcaag aagggcatgg tattgcaaaa gagatagagt tcaaaccagg
     3901 tccaagactc gatagcatag agataggtgg ttaaaaactc gctatcctcc tctgctagcg
     3961 gatagctttt atctaaggaa tggatggcat ctttaatcac gatggcattc aaacgacgat
     4021 aggtctctgc catctgttct tgctcgactt cctccaatag ttgttctaag ccaactatat
     4081 cttgatgggc aaagcgatcc acaacctttc taccaaatcg catatgtgga gattcttgat
     4141 agttgttgag cttgtgccca aactcatcaa aattcatatt gatcccttgg atggctaata
     4201 tgagcttatc tgcagacaac atagactgcc ctagttcaaa cttggacaac tgagaggctg
     4261 ttagaccagc acaagccaca tctgactgct tgagctttct agccaggcgc agttctttgt
     4321 aaaattctcc caattccatt ctctcgatca tctcaccacc tcctattttt tatatagtat
     4381 atcattgttt ttatagtttt gtcaaaacat tctgacactt tggtgattga aaaagccagc
     4441 cttaagctga ctctaaaagg accgagcctt gtacaataca gaactcaatc ctcgttctaa
     4501 atagaatgtc taactttttt gggcagtaca cgagcttggg gaacagccac tggaacgatg
     4561 aggtgtgagc tcaaaatatc ctccagttat gtttttccta atagtatacc ggaagagtga
     4621 aaggatttta taatggagcg gttacaaaga acctactttc tattaaacag tatactatga
     4681 aaatgtgaaa atttaacatt tttttgtaca aattttataa attattgcct ttttaatatc
     4741 aatagttaat ctcttatcca gatccccctt gtgtaaactt tatctttata agcttcaagg
     4801 cccctatccc atctatttgc aacaattaga tcactttgtt ttgtaaatag ttcaaaattc
     4861 ttttcaaaa
//
LOCUS       DAVLZG010000089         4560 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLZG010000089 DAVLZG010000000
VERSION     DAVLZG010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.089"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            8..187
                     /locus_tag="VYO72_001927"
     CDS             8..187
                     /locus_tag="VYO72_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708236.1"
                     /translation="MMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQYLVVITTII
                     LLYFFTLKKSKKYSF"
     gene            573..782
                     /locus_tag="VYO72_001928"
     CDS             573..782
                     /locus_tag="VYO72_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1708237.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            772..1260
                     /locus_tag="VYO72_001929"
     CDS             772..1260
                     /locus_tag="VYO72_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708238.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSCFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            1376..2836
                     /locus_tag="VYO72_001930"
     CDS             1376..2836
                     /locus_tag="VYO72_001930"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1708239.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            2833..3657
                     /gene="nadE"
                     /locus_tag="VYO72_001931"
     CDS             2833..3657
                     /gene="nadE"
                     /locus_tag="VYO72_001931"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1708240.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            3954..4505
                     /locus_tag="VYO72_001932"
     CDS             3954..4505
                     /locus_tag="VYO72_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1708241.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         1363 a          843 c         1036 g         1318 t
ORIGIN      
        1 aaatacgatg atgatgaata ctagtaatga tttgtttatc aaagcaattg aacttcttcc
       61 tttttattct ttacctgtat ttgtgacttc aaatacgatg tctattagtc agtatcttgt
      121 ggtaatcact acaatcattt tattgtactt tttcactctc aagaaaagca agaagtattc
      181 attttagttt catttagtat tattttgcat acctaaaata caataaaaaa atcagtcatc
      241 ttggtatgct cctgctttca ctattcaaca cgtttttgac ttatactagg ctcatttcca
      301 aaagcattat ataatagtga tatgaaacca actaaactaa acaagaaata taagcaataa
      361 aaactcgttt aaaagattct actaaagcta atactaaata aaaataaaag agtaaactag
      421 gaagtttatt tcaaacaacc taaaatactg attttcggct gaagataata ctggagtgca
      481 aattaatggg gttataataa atagctgata gcttgtgttg gttttggatt ttttaagagt
      541 agatgagtat taaaactata aggaggacga aggtggctaa aaatttaaaa ttaaaattag
      601 ctcgggtaga gcgtgattta acacaaggtc aactggcaga ggctgtcggg gtgacacgcc
      661 agactattgg tttgatagag gcgggaaaat acaatcccag tctctcgctc tgccagtcta
      721 tttgcagatg tttagggaaa accctagacc aactattttg ggaggaagaa gatgaaaaat
      781 agattttatt attatcaatt actagacgaa agagaagaac aactgttcaa taaagcgggc
      841 tctgaaagtt tctatatctg cattgctttg tcgctcctat cttatatcat ttcagtatta
      901 gcaccaagcc tttttaattc taatatgctg ctaatcgtta tcatcatagg gacattttac
      961 tttttcaatc gtgcccgtta tctgggagtg acctactata gttgttttca ttttacgatt
     1021 ttgggttgtt ttttcctaac cttggctatt acggctcttt tgatgttgca gaattatcaa
     1081 ttcaacatag aaatttatca gcacaatcct ttgaatttta aatacctgtc tgcttgggtc
     1141 attacttatg tcatttacct tccgtgggtc tttattggca atcttggtct taagagctat
     1201 ggcgaatggg ctcagaaaaa atttgaacaa gatatggatg aattggagag tggagaatag
     1261 cttgttactc ttttctcaat ccagctaaaa tgtgatataa tagtattaat ttattggaat
     1321 acatgaaagt tcttgaaaat tttcatgggt ttctagctaa ggaagtagga aaagtatgta
     1381 tccagatgat agtttgacat tgcacacgga cttgtaccag atcaacatga tgcaggttta
     1441 ctttgaccaa gggattcaca ataagaaggc ggtctttgag gtgtatttcc gccaacagcc
     1501 ttttaagaac ggctatgcgg tttttgcagg tttggaaaga attgtgaact atcttgaaga
     1561 cttgcgtttt tcagatagtg atatagccta tttggagtcg cttggttatc atggggcgtt
     1621 cttggattac cttcgcaatt tcaagttgga gttgaccgtt cgttctgccc aagaagggga
     1681 tttggttttt gctaatgaac cgattgtgca ggtggaagga cctctagccc aatgtcagtt
     1741 ggtcgaaacg gctcttttga acatcgtcaa ctaccagacc ttggtggcga cgaaggcagc
     1801 tcgtattcgt tcggttatcg aagatgaacc cttgatggag tttgggacac gtcgggctca
     1861 agaaatggat gcggccatct ggggaacacg cgcagctgtg attggtggcg ccaatggaac
     1921 cagcaacgtg cgtgcgggta agctctttga cattcctgtt ttgggaaccc atgcccatgc
     1981 cttggtacag gtttatggaa atgactatga agctttcaag gcttacgctg cgacccacaa
     2041 aaattgtgtc tttcttgtgg atacctatga cacccttcgc atcggtgtac cagctgccat
     2101 tcaggtggcg cgtgagctgg gtgatcagat taactttatg ggtgtgcgga ttgactctgg
     2161 ggatattgcc tacatttcta agaaagtccg tcagcaactg gacgaggctg gatttacaga
     2221 ggctaagatt tatgcttcta atgatttgga cgaaaatact atcctcaacc tcaagatgca
     2281 aaaggccaag attgatgtct ggggcgtggg taccaagctg attacagcat atgaccagcc
     2341 agctcttggg gcggtttaca agattgttgc aatcgaagat gaaactggtc agatgcgcaa
     2401 tacgattaag ctgtctaata atgctgaaaa agtctctacg ccaggtaaga agcaggtgtg
     2461 gcgcattacc agtcgtgaaa aaggtaagtc agaaggtgac tacatcactt atgatggtgt
     2521 ggatattagc tacatgacag aaatcaagat gttccatccg acctatacat acatcaagaa
     2581 gacggttcgt aattttgatg ccgttcctct cttggtggat atcttcaaag aaggaatatt
     2641 agtttacaac ttgcctagtt tgactgacat tcaggattat gcccgtaaag aatttgacaa
     2701 gttgtgggat gagtataagc gtgtgctcaa tccgcagcac tatccagtgg atttggcgcg
     2761 tgatgtatgg caagataaga tggacttgat tgataagatg cgcaaggaag cccttggtga
     2821 aggagaagaa gaatgagttt gcaagaaacg attatccaag agctgggtgt caaaccagtg
     2881 attgatgccc aggaagaaat ccgtcgttct attgatttct taaaaagata tctgaaaaaa
     2941 catcccttcc taaaaacctt tgtactaggg atttctgggg gacaagactc aaccttggca
     3001 gggcgtttgg cgcaattagc tatggaagaa ctgcgagctg aaacgggaga cgacagctac
     3061 aaatttatcg ctgtccgcct gccatacgga gtgcaagctg atgaagcaga tgctcaaaaa
     3121 gccctagcct tcatccagcc agatgtcagc ttggttgtga atatcaagga atcagctgat
     3181 gccatgacag ctgcagttga agcgacaggt agtcctgttt cagacttcaa caaggggaat
     3241 atcaaggcac gttgccgtat gattgctcag tatgcccttg ctggttccca tagcggagcg
     3301 gtcattggaa cagaccacgc cgcggaaaat atcacaggtt tctttaccaa gtttggtgac
     3361 ggcggtgcgg atattctccc tctttaccgc ctcaataaac gccaaggaaa acagctcttg
     3421 cagaaacttg gcgcagagcc agccctttat gaaaaaatcc caacggcaga cctagaagaa
     3481 gataaaccag gcctagctga cgaagtcgca cttggagtca cctatgcaga gattgacgat
     3541 tacctagaag gcaaaacaat cagcccagaa gctcaagcga ccattgaaaa ctggtggcac
     3601 aaaggccaac acaaacgcca cttacccatc accgtatttg atgacttttg ggagtaaaaa
     3661 cctccattgg aggtttttac cctgagccta gaaatgagaa agtgagagaa agtccggggg
     3721 atcttgaacc ccgagtttag aaataagaaa atgaggcaga ttcggtaact cgaagagttc
     3781 gatttcatcg tcttacccct gcaacgatga ctaggtttga aaaagcttgc tagatcgcat
     3841 ttcaaaccag gcagcgactg cgtcaagaaa ttagaagaca aactcgtttt ctagctgtta
     3901 ctgagttgag tctttttact acgagcatag aaataaggaa gtgaggtagc atcatgaaat
     3961 ctatcggtac gcaaatatta cagacagaac gtttgatttt aagaagattt gtggagagtg
     4021 atgcagaagc catgtttcaa aattgggctt catccgctga gaatttgacc tatgttacct
     4081 gggatcccca tcctgatgtc gaaatcactc gaaactcgat tcgcaattgg gttgcttcct
     4141 atactaatct caactattac aaatgggcca tttgtctaaa agaaaaccca gagcaagtga
     4201 taggagatat cagcatcgtt aagatagacg aggctgattt aagctgtgaa atcggctatg
     4261 tgctaggcaa ggcttactgg ggacatggta tgatgacaga ggccttgaaa gctgtcttgg
     4321 acttttgttt tactcaagca ggttttcaaa aggtcagagc acgttatgcc agtctcaacc
     4381 cagcttcagg tcgtgtcatg gaaaaggctg gaatgtccta tctacaaacc attgttaatg
     4441 gtgtagagag aaaaggctat cttgcggatc ttatttatta tggtataagt agggaagaat
     4501 gttgaattct attttctgtt tctatcgaag tcaactattt attgtaaata taataattag
//
LOCUS       DAVLZG010000090         4432 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLZG010000090 DAVLZG010000000
VERSION     DAVLZG010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.090"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            256..1659
                     /locus_tag="VYO72_001933"
     CDS             256..1659
                     /locus_tag="VYO72_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV1708242.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1848..2466
                     /locus_tag="VYO72_001934"
                     /pseudo
     CDS             1848..2466
                     /locus_tag="VYO72_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            2481..3221
                     /locus_tag="VYO72_001935"
     CDS             2481..3221
                     /locus_tag="VYO72_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708243.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3224..>4432
                     /locus_tag="VYO72_001936"
     CDS             3224..>4432
                     /locus_tag="VYO72_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708244.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLGDILIDDMN"
BASE COUNT         1544 a          559 c          831 g         1498 t
ORIGIN      
        1 agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata tggggggaat
       61 ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat attaagtttg
      121 atagaatttc ttggagattt tgttatggat tataatttca atttggagca tcctttcttt
      181 ttcactaata atgattatag tacagatact agcataaagt actaagtaag tctgcctttt
      241 aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat tggaaaattt
      301 gttgaaagac aagggtggaa aatacacatt agttcagagt ataatagttc acacgaattg
      361 ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca tcttagtaca
      421 gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc tggtaaattt
      481 attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt agaaagtgcc
      541 ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga agcaccaata
      601 tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt tgttattgat
      661 gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt taaaattcca
      721 aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga taaaaaacag
      781 ggagactttc cctttattat agataatgca attagatttt caaacagtgg tgggatatat
      841 aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag accgtataca
      901 ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg caaagcacta
      961 aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa gatctgggag
     1021 cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg ggttaccaat
     1081 aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag agtttcaaag
     1141 atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt atatcatcaa
     1201 gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat aatagactgg
     1261 gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc ccctggtttt
     1321 agagcatggc gagaaacact tcccagtgag atagattggt atggtattag acaaatagct
     1381 cattatttat acatgccact agtaactaca tcggatttga catacaacta tgtaagtcaa
     1441 accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga acatatagat
     1501 tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga gaatatttcc
     1561 aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga gcaagatata
     1621 caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc ttagcaaacg
     1681 ataaagtttt agggccgata caatcaattg cctattcatt aaataagata aatacaacca
     1741 aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt atagacgctg
     1801 aacatgataa taacggactg tatacttcat caatagatgt gatacacatg aaagatgttg
     1861 tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag tcaccattta
     1921 gggtattatt aacaggaact tctggtagtg ggaaaacaac gattttaaat ttaattaatg
     1981 gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa aagagttcag
     2041 attcaatacc aacagttgat cagacaccat atatttttga cactactatt cgtgagaacg
     2101 taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg ttaaaaaagg
     2161 taaatctata tgaagaatta gaaaagatag atatactaaa ttatcaatgt ggtgaaaatg
     2221 gtagtaattt gtctggaggt caaaaacaaa aaatagcttt agctagagct ctgattagaa
     2281 ataataaagt gtacttattt gacgaaatat cagctaattt agataatgat aattcaaatt
     2341 ccatacatga tattctgttc aatttaggta tttcatttat tgaagtttca catcattatg
     2401 acttaaatga caagagatac actgatatat aaattggaaa atggaacact tttcaaaatt
     2461 aagtgattgg aggcaagaat atggataaag attatatatt aaaagtgaaa gggctgtatc
     2521 atcaattttt actgggaaac aataaaacgt tgcaagtgct gaaaaatgtt tctctttctg
     2581 cttcgagagg agaatttata agtattctag gaattagtgg ttctggaaag tcaactttat
     2641 taaaatgtat ttctagtttg cttgaaccaa caagtgggga agtaatttta aatggaatca
     2701 acccctataa aatcagaaat gcaaaattgt caagtataag acgtaacgaa gtatctttta
     2761 tatttcaagc atacaattta ataccttccc tgccggtaat agaaaatata gcacttcctt
     2821 tgcgattatc acaaaaaaaa ttaactatta aaaatgtaga aaacttactc aaaagaatga
     2881 agtttaatgc tggcttaaac gattttgttg gaactctgtc tggtggagaa caacagaagg
     2941 ttgctatagc tagagcggtt attgctgata gtgatataat atttgctgat gagccaactg
     3001 gggctttaga cagcgtttct cgtgaagtaa tttttgaatt attgagagag ttagtagggg
     3061 cgggtaagtg tgtaattatg gtaacgcacg atatagaatt ggcctcgaaa actgatcgtg
     3121 cattaatatt gaaagatgga aaaattttca aagaacttca tagacctagc ggggaagagt
     3181 tgtataaaat cttagaggta caatcaacta cggaggaata gagatgctca gattagttta
     3241 ctatcaattt ttacataata agaaacaatg gttaggcgtt tcaccagtaa tttttgtttc
     3301 gagtttagtt atgggattgg ctgttaatgg ggtaattaat gttgagaata attcgcaagt
     3361 atttgtcgga cttccagatc ctaaaccaat ttttatgttt ccgatagtat tcggaggagt
     3421 aacattattc tttgtgctct ctaacataat aaatatgttg gttgaaattt ttagagatga
     3481 ttacgaactt ctggaggtgt tgggagcaag tctccttcaa ctatcatttc ttgtgggggg
     3541 acagattttt atcatttcct cgattattag ttttattgca tatctatgct ctatatttgt
     3601 tacgtcaaat tattattatt ttttacaata ctttttcggg gaaaatatat tacctgatat
     3661 ccaatttcaa acgagtgctg ttggatgtat cattacagta gtgttgattt catttttagc
     3721 ctttctaagt ggttgctttt atacgttcaa gaagattaga aataggaaga gttctaaaat
     3781 aaggcatgtt ctttcaatag taaaaagaat actgctattg gctggtttta gtgttatctg
     3841 gttgctttct ttgcaacaaa ttttccaaga tagcacaatt ttagcgaagg cccagataat
     3901 attcaatatt gtaatcttag atattgtgat tatttatcaa ttatctcctt ttatacagtc
     3961 atgttttatc aaactacttt ctataattat atttagaaat aattttatgt tcattgtttc
     4021 gaagtggaat ttactatatc gtaagcctta tataaaatct atcagtgctg caattacagg
     4081 agctatatta ctaatttcta gttttcaaat gatttctcag aatatactat ctcaatttca
     4141 agatgacagt gatttagagc taaaagtggc atttattgtc tatgtaggag caccaatttt
     4201 gatagtactt gcaaatatta tttcaattgc atttttgtca tcgcatcaag aaaggattga
     4261 gattcagcaa tttgaaattt taggaacttc taattaccag atggttaaga ttaaagttgg
     4321 tgaggctata tttttgacat ttgttacttc attaattgca tttttactta acattaaaat
     4381 tatggcttta atatactact ctttagggga tattttaata gatgatatga at
//
LOCUS       DAVLZG010000091         4431 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLZG010000091 DAVLZG010000000
VERSION     DAVLZG010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.091"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..224)
                     /locus_tag="VYO72_001937"
     CDS             complement(<1..224)
                     /locus_tag="VYO72_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1708245.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEE"
     gene            586..942
                     /locus_tag="VYO72_001938"
     CDS             586..942
                     /locus_tag="VYO72_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708246.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            947..1312
                     /locus_tag="VYO72_001939"
     CDS             947..1312
                     /locus_tag="VYO72_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1708247.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLIPGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            1299..3122
                     /locus_tag="VYO72_001940"
     CDS             1299..3122
                     /locus_tag="VYO72_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1708248.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            3236..4102
                     /locus_tag="VYO72_001941"
     CDS             3236..4102
                     /locus_tag="VYO72_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1708249.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
BASE COUNT         1576 a          667 c          880 g         1308 t
ORIGIN      
        1 tcttcttcat ttcttctatt atcatcattg tttacaccga ttatatctaa agtgatatta
       61 tcaattccaa agatgatata acaatcttcg tgatgtgatg tattgacaaa atttaagata
      121 tcacgcacca attcagtttt tgaatgatgc catttttgtt taaaatcatg aaactcatct
      181 tcgggtgtat tcaatagtaa gtgtatttga tctagactca gcatttttat ttctccaaat
      241 attagtttac agaaatttta tcatagaatc agagaaagtc aatcataact atattagctg
      301 tgataccttt ttcaaatctt ccctgttatc ctaatatcat tcatagaaaa tcaatttttg
      361 attttctatg ggggtttggg ggcgaagtca ccaagttatc ttatcgttgg ctgtcaaaac
      421 tagaaagttt tgataggctg gcgatatgat ttttgagata ttgtggacac aatatctgag
      481 ctcgcaaagc cttacaagaa tgaaaatcag ttgttggaaa agtgtactga cattgtatgg
      541 tagctcacat tgtcagtaca agtattttgg aaaggaagta gcagtatgaa acgagatgtg
      601 cgtgatattc ggaaacaatt tcgtttaaca gaagcagaag aaaagcaaat tctagctttg
      661 atgagagagc ggggagagac taatttctct gattttcttc gtaaaagttt actttcctct
      721 gatttacaaa aacagatgga gacatggttt gccctctggc aatcccaaaa actagaacaa
      781 atcagtcgtg acgttcatga agttttaatc ttggcacagt cagaacgtca agtcacccaa
      841 gagcatgtat ctattctctt aacgtgcgtg caggaattga ttcaagaggt tgcaaacacc
      901 atacccctca gtaaagaatt tcgtgagaag tacatgaggt aagcacatgg aacatcgtta
      961 ccgaaccaat ctcaagaaag tgtttttgtc tgatagtgag ttgaaccaac taaatataaa
     1021 tatcgatcaa agtggttgta aatccttttc tgaatatgcg agacgaactc tactcgatcc
     1081 tggtatgaat tttatcacga ttgacacaaa cggttaccaa gatttagtgt ttgagttaaa
     1141 gaggattggc aataatatca accagattgc tcgaagtgtt aatcaatctc agttaattcc
     1201 tggtgaagaa ttgcaggagt tgaaaaaagg aattggtgaa ttgataaaag aagttgataa
     1261 ggaatttaat ctgcaagcgc agaagctaaa ggagttccat ggtcatcact aaacactttg
     1321 ccattcacgg aaagagttac cgcagaaagc ttatcaagta cattctcaat cctgagaaaa
     1381 ccaataatct tgccttggtg tcggactatg gcatgaagaa ttttctggac tttcctagct
     1441 atgaggaaat ggtgcagatg tatcatgaaa atttcatcag caacgatacg ctttacgatt
     1501 ttcgccacga caggatggaa gaaaatcaac gaaaaataca cgctcaccac atcattcagt
     1561 ctttctcgcc agaggatcat ctcactcctg aacaaatcaa tcggataggt tatgagactg
     1621 tgaaggaatt aactggtggc aaatttcgtt ttatcgttgc gacccatgtt gataaagacc
     1681 acctgcacaa tcacatcatt atcaattcag tagatagcaa ttctgacaaa aagctcaagt
     1741 gggactacaa ggtggagcga aatcttcgca tgatttctga ccgtttttct aaaatcgcag
     1801 gtgctaaaat cattgagaac cgctattctc accagcggta tgaagtctat cgtaagacta
     1861 atcacaagta tgaactcaag cagcgactct attttttgat ggaacattct agggactttg
     1921 aggatttcaa aaagaatgct ccgctactac atgtggagat ggatttccgt cacaagcatg
     1981 ccaccttttt tattacggac tcaactatga aacaggtggt gcgtggcaag caactcaatc
     2041 gcaagcagcc ttacacagaa gaatttttta agaactactt tgccaaaaga gaaatagaaa
     2101 gtctcatgga atttttattg ctgaaagttg agaatatgga tgatttactt cagaaagcaa
     2161 aactttttgg actaactatc aatcctaaac aaaagcatgt ttcttttcaa tttgcaggag
     2221 tggaggtaaa ggagacagag ctagaccaga aaaatcttta tgatgtagag tttttccaag
     2281 attattttaa aaatagaaaa gattggcaag ctccagaaac tgaggatttc gttcaacttt
     2341 atcaagaaga aaagttatcc aaagaaaaag aacttccaag cgatgagaag ttctgggagt
     2401 cctatcaaga gttcaagagt aacagagatg ccgttcatga atttgaggtg gagttgtcac
     2461 tcaatcaaat tgaaaaagta gtggatgatg gaatttacgt caaggtcaag tttggtattc
     2521 gtcaggaggg acttatcttt gtgccgaaca tgcagcttga tatggaagag gataaggtga
     2581 aggttttcat cagggaaacc agctcctact atgtctacca caaagacgct gccgagaaaa
     2641 attgttatat gaaaggtcga accttaatta gacagttcag ctatgaaaat caaaccattc
     2701 cattacgcag aaaagcgaca gtcgatatga ttaaagagaa gattgcggaa gtggatgctt
     2761 tgattgaact ggaagtagaa aatcaatctt atgtcacgat taaagatgag ttagtgcatg
     2821 aactagcagc gtctgaatta agaatcaatg agttgcaaga acgaatgtca accttgaatc
     2881 aagtagcaga atatctactg gcttcagttg aaagtaagca agaaatgaaa ttaaatcttt
     2941 caaaactgaa tataactgag aatatcagtg ctaatattgt tgagaaaaaa ttgaagagcc
     3001 tggggaatca actggaattg gaaaggggca ggtatgaaaa gatggtagtc aggctagata
     3061 aatttataaa tcgcttaaat acaggacttt caaaaggaga tgggatagat tttcaaaaat
     3121 aggaatctag ccaataatta tatacaatgt gtatcttttg taaaatatat ttgaaattta
     3181 gatttaatca tgttacaatt aacattgaaa tcaaatagaa aaggaagatg caaacgtggg
     3241 tacactatta gcaacaagat taaaaaatag acgaaaagaa ttaaaaatgt ctcagcgaga
     3301 attagctgag ggtatctgta aacaggggca aattagtcga ttagagagtg gagagttcac
     3361 ccctggagcg gattttttac atgcccttgc taagaaatta aaagttagta tggactactt
     3421 ttttgatgag caggttgtag aggaagtcaa tgagttatca gagtttaaga agttagcaca
     3481 gacatttatc acaaatcgta attatgaatc tttaaaatat atatatgaat tggaaaatgt
     3541 aaaagcccat cgcttatctc tagcagataa attttacatg gaatggataa agtctcttat
     3601 agatttttat ttttatggac agaaagaaga ggcaattaca cgattagaga atatgctacc
     3661 tcagttaaat gtatctgatt tgaactacct tcaagtttca aacactctat tcaattttta
     3721 ttatgatatt gaagatttag aacgttttaa tgagattaga gacaagctag agcatcaagt
     3781 gaatcagctt aatttaaaca caattgaaga gttagaacta tcaattaagt tcaattataa
     3841 cgtttgtcga tacctatggt tacagaaaaa tattgaagaa gctattacga aaatcacagc
     3901 tacgataaag caatgtaagg agtacaggac aacttatcta ttagctgatt tgtatttatt
     3961 gatgggaagt gtaagtgaaa atttttcttc taaaagttca gtaaaagaat attttgagac
     4021 tgctcatttt ctctacaaac ttgaggaaaa catgtcaatg gctttgaaag tcgaacatta
     4081 ttttgcagat ataacagaat aaggaatacg gtgttctagt gagcatcgtt ttttaaatct
     4141 aatttgaata caaaaaagta ttaaataaaa aaaaataaaa aaagattata aaaatacttg
     4201 acaagctaat tttgaagtga taaaataaat gcaagaaaac gaaaggagag gtatatgaga
     4261 agtttgttta ggaaaattgt tgctttgtta gtcataggat taatcctatt agggactgct
     4321 ggaggaactc aagttcataa gatggctaga gggattgatc aaggtcctgc gaatggtatt
     4381 tatagatagg agattatagt cacttaaaaa tcaacaaatt ataaaatttt t
//
LOCUS       DAVLZG010000092         4179 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLZG010000092 DAVLZG010000000
VERSION     DAVLZG010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.092"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            229..2730
                     /locus_tag="VYO72_001942"
     CDS             229..2730
                     /locus_tag="VYO72_001942"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1708250.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            3030..3722
                     /locus_tag="VYO72_001943"
                     /pseudo
     CDS             3030..3722
                     /locus_tag="VYO72_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            3734..4150
                     /locus_tag="VYO72_001944"
                     /pseudo
     CDS             3734..4150
                     /locus_tag="VYO72_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1254 a          796 c          964 g         1165 t
ORIGIN      
        1 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcgtc
       61 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      121 catagtcatc aaaattaatg agatacagta tacagttttt tctttaaaca catttcaaat
      181 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttat
      241 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      301 acaggaacag atacatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      361 ggagttggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      421 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      481 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      541 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      601 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      661 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      721 gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg ctatccagtt
      781 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      841 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      901 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
      961 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtctt ggctcctgaa
     1021 catgaattag tagacgctat cacaagttca gagcaagcag aagctgtagc agactataaa
     1081 caccaagcca gccttaagtc tgacttggtt cgtacagacc ttgctaagga aaaaactggt
     1141 gtttggacag gtgcctatgc catcaaccct gtcaatggta aggaaatgcc aatctggatt
     1201 gcggactatg ttcttgctag ttatggaaca ggtgcggtta tggctgtgcc tgcccacgac
     1261 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1321 ggaaatgtcg aagaagctgc ctacacagag gatggcctgc atgtcaattc agacttccta
     1381 gatggattga ataaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1441 tgtggtcagg agaaggttac ctaccgcctc cgcgactggc tctttagccg tcaacgttac
     1501 tggggtgagc caattccaat cattcattgg gaagatggaa cttcaacagc tgttcctgaa
     1561 actgaattgc cgcttgtctt gcctgtaacc aaggatatcc gtccttcagg tactggtgaa
     1621 agtccactag ctaacttgac agattggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1681 cgtcgtgaaa ctaacaccat gccacaatgg gctggttcaa gctggtacta cctccgctat
     1741 attgacccgc acaatactga gaaattggct gatgaggacc tcctcaaaca atggttgcca
     1801 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta tgctcgtttc
     1861 tggcataaat tcctctatga cctcggtgtt gttccgacta aggaaccatt ccaaaaactc
     1921 tttaaccaag ggatgatttt gggaacaagc taccgtgacc accgtggtgc tcttgtggca
     1981 accgacaagg ttgaaaaacg tgatggttcc ttctttcatg tagaaacagg ggaagagttg
     2041 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgttaaccc agacgatgtg
     2101 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgtttatggg accactcgat
     2161 gcttcgattg cttggtcaga agaaggtttg gaaggaagcc gtaagttcct tgaccgagtt
     2221 taccgtttga ttacaagtaa agaaatcctt gcggaaaaca atggtgctct tgacaaggtt
     2281 tacaacgaaa cagtcaaagc tgttactgag caaattgagt ctctcaaatt caacacagct
     2341 attgcccaac ttatggtctt tgtcaatgct gctaacaagg aagataagct ttatgttgac
     2401 tatgccaaag gctttattca attgattgca ccatttgcac ctcacttggc agaagaactc
     2461 tggcaaacag tcgcagaaac aggtgagtca atctcttatg tagcttggcc aacttgggac
     2521 gaaagcaaat tggttgaaga tgaaattgaa attgttgtcc aaatcaaagg aaaagtccgt
     2581 gccaaactca tggttgctaa agatatatca cgtgaagaat tacaagaaat cgctttagct
     2641 gatgaaaaag tcaaagcaga aattgacggt aaggaaatcg tgaaagtaat tgcggtaccg
     2701 aataaactcg ttaatatcgt cgttaaataa cgagtttatt agctctatct gccaccttca
     2761 atagtccact ggactattga agccaactaa attagttaac attgttgtga aataagatag
     2821 gaatccttca gagtagaatc tggaggattt tttgaacctt cttatgaaag tatgatatat
     2881 agtagactga atctaaaata gtacgaaaca attgctaaaa catttataga aattaatttt
     2941 actttcccaa tcgatttgtt ctcatcttat ttcaatacgc tatactatgg gcaactataa
     3001 agtttgaaaa gcgaaacaag gagaaagtta taccagtaaa cgaatatggt cagatgattg
     3061 gtgagtcaat ggaaggttat acaccaggtg aactgacttt tattgatctc ttagaagggc
     3121 gttatgctag gatagaggct ctttcagtgg aaaagcatgc ggaggatttg ctagctgttt
     3181 atggtcctga tactcctcag gagatgtgga cctacctctt tcaggagcca gtagcagaca
     3241 ttgaggaact ggtcagcctt ttaaatcaga tgttggtcgt aaggaccgtt tttactatgc
     3301 aatcatagac aaggcaactg gtaaggcttt gggaactttt tctctcatgc gtattgacca
     3361 gtaacggagt aatagaagtg ggagctgtca ctttttctcc aaaactcagg gggacacgga
     3421 tagggacaga agcccagtat ctactggctc gctatgtctt tgaagagctt aactatcgtc
     3481 gttatgagtg gaaatgcgat gctcttaacc tgccatccag acgtgctgcg gagcgtttgg
     3541 gctttattta tgaaggaacc ttccgtcagg cagtggttta taaggggcgt acgagagata
     3601 tggattggtt gtctatgatt gataaggact ggcccaaagt caaagatcgt ttggaaacat
     3661 ggttgcgtcc tgaaaatttt gataaaaatg gacagcagta caagagcttg agagagtttt
     3721 aagaggtgtt gacatgatca ctattagaaa gcaagaaatc gtcaagttcg aggatgtttt
     3781 gcatctctat caggctgtcg gttggacaaa ttatacaaat caacctcaga tgctggagta
     3841 gaccttgtat cattcattaa taatttatct ggcacttgat ggtgatgctg ttgtgggctt
     3901 gattcgtttg gttggagatg gtttttcatc agtttttgta caggatttga ttgttttgtc
     3961 tagctatcag cgccaaggga ttggtagctc cttgatgaaa caggctttag gaaattttaa
     4021 agaggcctat caagtccagc tggcgacaga acagacagaa aaaaacgtgg gatttaatcg
     4081 ttctatgggc tttgaaatct tatccaccta taattggata gggatgactt ggatgaatcg
     4141 taaaaaataa caaaacttgt tttttcttaa gcaaaattt
//
LOCUS       DAVLZG010000093         4136 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLZG010000093 DAVLZG010000000
VERSION     DAVLZG010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.093"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(115..390)
                     /locus_tag="VYO72_001945"
     CDS             complement(115..390)
                     /locus_tag="VYO72_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1708251.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(496..1335)
                     /locus_tag="VYO72_001946"
     CDS             complement(496..1335)
                     /locus_tag="VYO72_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1708252.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1477..2325
                     /locus_tag="VYO72_001947"
     CDS             1477..2325
                     /locus_tag="VYO72_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1708253.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFIFGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2418..3335)
                     /locus_tag="VYO72_001948"
     CDS             complement(2418..3335)
                     /locus_tag="VYO72_001948"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1708254.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VYO72_001949"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VYO72_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT         1281 a          827 c          679 g         1349 t
ORIGIN      
        1 tacaatattt tcggaacatt caacttttta actctattta ttactagatt tcataattaa
       61 aaagcctact gaccaagcta gaaagcttga tacaataggc tttttaaaga ctgattattt
      121 aacagcgtct ttaagagctt taccagcttt gaatgctggt actttagaag ctgcaattgt
      181 catttcttta ccagtttgtg ggttgcgacc tttacgttct gcacgctcac gaacttcaaa
      241 gttaccaaaa ccgatcaatt gaactttttc accagctgca agatagtcag ctactgctgc
      301 aaatacagct tcaactgctg ctgctgagtc tttcttagtc aattctgtag cttctgctac
      361 tttagcgatc aaatcttgtt tgtttgccat gttaatgatt cctccagata atttctaatt
      421 aacaaatata atcatatcct aaaatccctt ttaggtcaag ttaaaaacgc tatttcttcc
      481 aattttattt attttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
      541 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
      601 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
      661 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
      721 agttccacga cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacaacacg
      781 gatattgaga agggagctca acaagccagt tacacggcca attcgtccac ctttgacaag
      841 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
      901 agataaaatt gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
      961 gaatttcagg gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag
     1021 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
     1081 aagaatctgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
     1141 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
     1201 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
     1261 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
     1321 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
     1381 ctaattatat caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa
     1441 tttgatataa tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt
     1501 tttaccattt tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc
     1561 catcatctct ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa
     1621 atccctgttt ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag
     1681 atctttggag ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg
     1741 ttagcttttt ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca
     1801 gcccttatag cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt
     1861 acaactggcg gaactgatat tctagctcgt attctcaaca aatacactca tatatccata
     1921 ggaaaactgc tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag
     1981 gatttgagat tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat
     2041 ttgattggtg aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac
     2101 caacttgcta aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttttggtcaa
     2161 ggctactata gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt
     2221 gtgaaaacga aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa
     2281 gcccatgaaa tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg
     2341 tgacctcaaa agttagacta aatcatctat cttttgggtt acagacaacc tcttttttgt
     2401 tttatttact caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga
     2461 tccactaatt ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa
     2521 accatgacgg tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt
     2581 gcttcttctc catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt
     2641 ctttgaatct caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa
     2701 agcactaaat tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc
     2761 atacctcttg atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct
     2821 aaaatagctt gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga
     2881 acaatgataa cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa
     2941 ccaaatgtat aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt
     3001 gcaaagaatt cttgtgcagt gagactagcg aattgactac taaaatcaag gagatataat
     3061 tcttctacac cttcgcgctt tagttttctt tcacgttcag cagggttcaa aatatgcaaa
     3121 aacaaatctg gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg
     3181 acgataggta ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc
     3241 cccttatgta tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata
     3301 tctttttggt tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc
     3361 tatttctgga acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca
     3421 aaaagcactt tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact
     3481 tgtaggacat cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg
     3541 tcatactatg cttatgtatg aaaaagcaat gcaactaact cctgagaact ttaaattact
     3601 aattggtgcc gaaaaggtag aatttagaat cgaggtacac ctatggctgt aaaatttaca
     3661 aaatgagaca acttgggcaa gatgtttgaa gaatttccta aactccctga tttgaagcaa
     3721 gtcactttcc ctgatgacaa aaaaagccaa agcagtaaag aaaaactaga tgactgcttt
     3781 ccaacaactt ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 gccattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcaaatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaag
//
LOCUS       DAVLZG010000094         3802 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLZG010000094 DAVLZG010000000
VERSION     DAVLZG010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.094"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            79..306
                     /locus_tag="VYO72_001950"
     CDS             79..306
                     /locus_tag="VYO72_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708255.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            594..3491
                     /gene="nanA"
                     /locus_tag="VYO72_001951"
     CDS             594..3491
                     /gene="nanA"
                     /locus_tag="VYO72_001951"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1708256.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWIKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1291 a          644 c          852 g         1015 t
ORIGIN      
        1 gattgctgta aaaatagtag tagctatgcg aaataacaga tagagagaag ggattgaagc
       61 ttagaaaagg ggaataatat gatatttaag gcattcaaga caaaaaagca gagaaaaaga
      121 caagttgaac tacttttgac agtttttttc gacagttttc tgattgattt atttcttcac
      181 ttatttggga ttgtcccctt taagctggat aagattctga ttgtgagctt gattatattt
      241 cccattattt ctacaagtat ttatgcttat gaaaagctat ttgaaaaagt gttcgataag
      301 gattgagcag gaagtatggt ataaatagca taagctgatg tccatcattt gcttataaag
      361 agatatttta gtttaattgc agcggtgtcc tggtagataa actagattgg caggagtctg
      421 attggagaaa ggagagggga aaattggcac caatttgaga tagtttgttt agttcatttt
      481 tgtcatttaa atgaactgta gtaaaagaaa gttaataaaa gacaaactaa gtgcattttc
      541 tggagtaaat gtcttatttc agaaatcggg atatagatat agagaggatc agtatgaatc
      601 ggagtgttca agaacgtaag tgtcgttata gcattaggaa actatcggta ggagcggttt
      661 ctatgattgt aggagcagtg gtatttggaa cgtctcctgt tttagctcaa gaaggggcaa
      721 gtgagcaacc tctggcaaat gaaactcaac tttcggggga gagctcaacc ctaactgata
      781 cagaaaagag ccagccttct tcagagactg aactttctgg caataagcaa gaacaagaaa
      841 ggaaagataa gcaagaagaa aaaattccaa gagattacta tgcacgagat ttggaaaatg
      901 tcgaaacagt gatagaaaaa gaagatgttg aaaccaatgc ttcaaatggt cagagagttg
      961 atttatcaag tgaactagat aaactaaaga aacttgaaaa cgcaacagtt cacatggagt
     1021 ttaagccaga tgccaaggct ccagcattct ataatctctt ttctgtgtca agtgctacta
     1081 aaaaagatga gtacttcact atggcagttt acaataatac tgctactcta gaggggcgtg
     1141 gttcggatgg gaaacagttt tacaataatt acaacgatgc acccttaaaa gttaaaccag
     1201 gtcagtggaa ttctgtgact ttcacagttg aaaaaccgac accagaacta cctaaaggcc
     1261 gagtgcgcct ctacgtaaac ggggtattat ctcgaacaag tctgaaatct ggcaatttca
     1321 ttaaagatat gccagatgta acgcatgtac aaatcggagc aaccaagcgt gccaacaata
     1381 cggtttgggg gtcaaatcta cagattcgga atctcactgt gtataatcgt gctttaacac
     1441 cagaagaggt acaaaaacgt agtcaacttt ttaaacgctc agatttagaa aaaaaactac
     1501 ctgaaggagc ggctttaaca gagaaaacgg acatattcga aagcgggcgt aacggtaaac
     1561 caaataaaga tggaatcaag agttatcgta ttccagcact tctcaagaca gataaaggaa
     1621 ctttgatcgc aggtgcagat gaacgccgtc tccattcgag tgactggggt gatatcggta
     1681 tggtcatcag acgtagtgaa gataatggta aaacttgggg tgaccgagta accattacca
     1741 acttacgtga caatccaaaa gcttctgacc catcgatcgg ttcaccagtg aatatcgata
     1801 tggtgttggt tcaagatcct gaaaccaaac gaatcttttc tatctatgac atgttcccag
     1861 aagggaaggg aatctttgga atgtcttcac aaaaagaaga agcctacaaa aaaatcgatg
     1921 gaaaaaccta tcaaatcctc tatcgtgaag gagaaaaggg agcttatacc attcgagaaa
     1981 atggtactgt ctatacacca gatggtaagg cgacagacta tcgcgttgtt gtagatcctg
     2041 ttaaaccagc ctatagcgac aagggtgatc tatacaaggg tgaccaatta ctaggcaata
     2101 tctacttcac aacaaacaaa acttctccat ttagaattgc caaggatagc tatctatgga
     2161 tgtcctacag tgatgacgac gggaagacat ggtcagcgcc tcaagatatt actccgatgg
     2221 tcaaagccga ttggatgaaa ttcttgggtg taggtcctgg aacaggaatt gtacttcgga
     2281 atgggcctca caagggacgg attttgatac cggtttatac gactaataat gtatctcact
     2341 tagatggctc gcaatcttct cgtgtcatct attcagatga tcatggaaaa acttggcatg
     2401 ctggagaagc ggtcaacgat aaccgtcagg tagacggtca aaagatccac tcttctacga
     2461 tgaacaatag acgtgcgcaa aatacagaat caacggtggt acaactaaac aatggagatg
     2521 ttaaactctt tatgcgtggt ttgactggag atcttcaggt tgctacaagt aaagacggag
     2581 gagtgacttg ggagaaggat atcaaacgtt atccacaggt taaagatgtc tatgttcaaa
     2641 tgtctgctat ccatacgatg cataatggaa aagaatacat tatcctcagc aatgcaggtg
     2701 gaccgaaacg tgaaaatggg atggtccact tggctcgtgt cgaagaaaat ggtgagttga
     2761 cttggatcaa acacaatcca attcaaaaag gagagtttgc ctataattcg ctccaagaat
     2821 taggaaatgg ggagtatggc atcttgtatg aacatactga aaaaggacaa aatgcctata
     2881 ccctatcatt tagaaaattt aattgggact ttttgagcaa agatctgatt tctcctaccg
     2941 aagcgaaagt gaagcgaact agagagatgg gcaaaggaga gatgggcaaa ggagttattg
     3001 gcttggagtt cgactcagaa gtattggtca acaaggctcc aacccttcaa ttggcaaatg
     3061 gtaaaacagc gactttccta acccagtatg atagcaagac cttgttattt gcagtagata
     3121 aggaagatat cggacaggaa attattggta tagctaaagg aagcatcgaa agtatgcata
     3181 atcttcctgt aaatctagca ggtgccagag ttcctggcgg agtaaatggt agcaaagcag
     3241 cggtgcatga agttccagaa tttacagggg gagttaatgg tacagagcca gctgttcatg
     3301 aaatcgcaga gtataaggga tctgattcgc ttgtaactct tactacaaaa gaagattata
     3361 cttacaaagc tcctcttgct cagcaggcac ttcctgaaac aggaaacaag gagagtgacc
     3421 tcctagcttc actaggacta acagctttct tccttggtct gtttacgcta gggaaaaaga
     3481 gagaacaata agagaagaat tctaaacatt tgattttgta aaaatagaag gagatagcag
     3541 gttttcaagc ctgctatctt tttttgatga cattcaggct gatacgaaat cataagaggt
     3601 ctgaaactac tttcagagta gtctgttcta taaaatatag tagattgaaa taagatgtga
     3661 acaactctat caggaaagtc aaattaattt atagaaaaat tttagcagtc aaggtgtact
     3721 gttatagatt caatatatta tgcgactatt aaccttgtct tctcctaaaa ttgactttct
     3781 tgttttctta tcttgtccac tc
//
LOCUS       DAVLZG010000095         3405 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLZG010000095 DAVLZG010000000
VERSION     DAVLZG010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.095"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VYO72_001952"
     CDS             complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VYO72_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1708257.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(995..2047)
                     /locus_tag="VYO72_001953"
     CDS             complement(995..2047)
                     /locus_tag="VYO72_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1708258.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2044..2742)
                     /locus_tag="VYO72_001954"
     CDS             complement(2044..2742)
                     /locus_tag="VYO72_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1708259.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2909..>3405)
                     /locus_tag="VYO72_001955"
     CDS             complement(2909..>3405)
                     /locus_tag="VYO72_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV1708260.1"
                     /translation="ALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDN
                     IVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTN
                     TMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNK
                     KEEN"
BASE COUNT          942 a          765 c          651 g         1047 t
ORIGIN      
        1 ccataaaaga ttataccaca ttgtgtacta tttttggttc attttactat atcactttgg
       61 actatatcgg tctagttatg tctaaacgat tatagctgga tactaagaga aatcaaaaaa
      121 gcactaaggg agaacgtccc aaagtgctta gtttcaaggc tttacagcct atcttattta
      181 ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg
      241 ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaatttttc agcgtcgaat
      301 gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc tggaactttc
      361 aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga tgggatatca
      421 acgcgtttcc cgtcaacaag gatgtgaccg tggtttacaa attgacgagc ttgacgacga
      481 gtagtcgcga gaccaagacg gtaaacaacg ttatccaaac gacgttccaa aagaagcata
      541 aagttgaaac ctaggattcc gcctttgatt tttgtagctt gtacaaacaa gttacggaat
      601 tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg
      661 tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt
      721 gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg tttccaagat
      781 ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt cggtggaaat
      841 agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt
      901 atcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac acaaaattca
      961 ttctaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca ctaccagaga
     1021 ggttgagaac gagagtaaag gtacttccta gaccgtactg gctgctgact gtgatttccc
     1081 cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct
     1141 tcatgttacg cgaagtttcg acacgataaa ggcgtttgaa aatattttcc aaatcctctg
     1201 gggcaatgcc ctgcccttca tcggtcacac tgattgaaag ctggcccttc tccagcttag
     1261 ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg accagattca
     1321 ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct gggattacct
     1381 gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc atgcactcaa
     1441 ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga tttctagctg
     1501 tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc gtctggcgtc
     1561 caatggttgc tagataatga gcttgctccg actccttgat aatcccatcc aaaatccctt
     1621 ctaccgtcgc ttggatcgaa gtgataggag tcttaatatc atgcgacaac tgagcaatca
     1681 tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc aaatcatggg
     1741 acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga acctccaaat
     1801 ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg cccaacgacg
     1861 taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg gcaacgatgg
     1921 tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga acagcccaaa
     1981 aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata taacttttta
     2041 gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa ctgtcttaat
     2101 agtgggcgtt tggtcactac tatattttgc cagctcctgt cgaagagcat ggatatgcac
     2161 attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat agaggtctgt
     2221 cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa atgatttaac
     2281 agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat tcatttttag
     2341 attgccaagg gaaatcagct ctgtttcgcc cccacgatga aggcggcgca aaatattgtg
     2401 gacacgcaaa actagctcac gtgggctaaa aggcttagca ataaaatcat ctgctcccaa
     2461 gctcaggccg taaatcttgt cctgctcact ggtcttagca gtaataaata ggaaaggctg
     2521 ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc gaggcatcat
     2581 gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg cttccagtcc
     2641 atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat gaatatctgt
     2701 gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct cctttgataa
     2761 aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga tgattttaat
     2821 ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct tagtcagccc
     2881 actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt ttcaaaccta
     2941 gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc attgatgttt
     3001 gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta tcagacatct
     3061 tgttagcaga agcagccata ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt
     3121 cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga gtcacgccag
     3181 aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct ttaacattta
     3241 tcttaatagt gactttttta gttgctacga tgttgtccaa gtctggttta ccgtctttgt
     3301 taccatagac attgactgta gcactgtaag tttgagtacc atttgctcgg aactggtcaa
     3361 tgagcgcttg tttttctttg ccagctacat ttccgtccaa ggcta
//
LOCUS       DAVLZG010000096         3275 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLZG010000096 DAVLZG010000000
VERSION     DAVLZG010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.096"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            41..3160
                     /gene="phtE"
                     /locus_tag="VYO72_001956"
     CDS             41..3160
                     /gene="phtE"
                     /locus_tag="VYO72_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1708261.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNLADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1215 a          539 c          637 g          884 t
ORIGIN      
        1 gttgagaaaa aacttcatca tttattgaaa tgagggattt atgaaattta gtaaaaaata
       61 tatagcagct ggatcagctg ttatcgtatc cttgagtcta tgtgcctatg cactaaacca
      121 gcatcgttcg caggaaaata aggacaataa tcgtgtctct tatgtggatg gcagccagtc
      181 aagtcagaaa agtgaaaact tgacaccaga ccaggttagc cagaaagaag gaattcaggc
      241 tgagcaaatt gtaatcaaaa ttacagatca gggctatgta acgtcacacg gtgaccacta
      301 tcattactat aatgggaaag ttccttatga tgccctcttt agtgaagaac tcttgatgaa
      361 ggatccaaac tatcaactta aagacgctga tattgtcaat gaagtcaagg gtggttatat
      421 catcaaggtc gatggaaaat attatgtcta cctgaaagat gcagctcatg ctgataatgt
      481 tcgaactaaa gatgaaatca atcgtcaaaa acaagaacat gtcaaagata atgagaaggt
      541 taactctaat gttgctgtag caaggtctca gggacgatat acgacaaatg atggttatgt
      601 ctttaatcta gctgatatta tcgaagatac gggtaatgct tatatcgttc ctcatggagg
      661 tcactatcac tacattccca aaagcgattt atctgctagt gaattagcag cagctaaagc
      721 acatctggct ggaaaaaata tgcaaccgag tcagttaagc tattcttcaa cagctagtga
      781 caataacacg caatctgtag caaaaggatc aactagcaag ccagcaaata aatctgaaaa
      841 tctccagagt cttttgaagg aactctatga ttcacctagc gcccaacgtt acagtgaatc
      901 agatggcctg gtctttgacc ctgctaagat tatcagtcgt acaccaaatg gagttgcgat
      961 tccgcatggc gaccattacc actttattcc ttacagcaag ctttctgcct tagaagaaaa
     1021 gattgccaga atggtgccta tcagtggaac tggttctaca gtttctacaa atgcaaaacc
     1081 taatgaagta gtgtctagtc taggcagtct ttcaagcaat ccttcttctt taacgacaag
     1141 taaggagctc tcttcagcat ctgatggtta tatttttaat ccaaaagata tcgttgaaga
     1201 aacggctaca gcttatattg taagacatgg tgatcatttc cattacattc caaaatcaaa
     1261 tcaaattggg caaccgactc ttccaaacaa tagtctagca acaccttctc catctcttcc
     1321 aatcaatcca ggaacttcac atgagaaaca tgaagaagat ggatacggat ttgatgctaa
     1381 tcgtattatc gctgaagatg aatcaggttt tgtcatgagt cacggagacc acaatcatta
     1441 tttcttcaag aaggacttga cagaagagca aattaaggct gcgcaaaaac atttagagga
     1501 agttaaaact agtcataatg gattagattc tttgtcatct catgaacagg attatccaag
     1561 taatgccaaa gaaatgaaag atttagataa aaaaatcgaa gaaaaaattg ctggcattat
     1621 gaaacaatat ggtgtcaaac gtgaaagtat tgtcgtgaat aaagaaaaaa atgcgattat
     1681 ttatccgcat ggagatcacc atcatgcaga tccgattgat gaacataaac cggttggaat
     1741 tggtcattct cacagtaact atgaactgtt taaacccgaa gaaggagttg ctaaaaaaga
     1801 agggaataaa gtttatactg gagaagaatt aacgaatgtt gttaatttgt taaaaaatag
     1861 tacgtttaat aatcaaaact ttactctagc caatggtcaa aaacgcgttt cttttagttt
     1921 tccgcctgaa ttggagaaaa aattaggtat caatatgcta gtaaaattaa taacaccaga
     1981 tggaaaagta ttggagaaag tatctggtaa agtatttgga gaaggagtag ggaatattgc
     2041 aaactttgaa ttagatcaac cttatttacc aggacaaaca tttaagtata ctatcgcttc
     2101 aaaagattat ccagaagtaa gttatgatgg tacatttaca gttccaacct ctttagctta
     2161 caaaatggcc agtcaaacga ttttctatcc tttccatgca ggggatactt atttaagagt
     2221 gaaccctcaa tttgcagtgc ctaaaggaac tgatgcttta gtcagagtgt ttgatgaatt
     2281 tcatggaaat gcttatttag aaaataacta taaagttggt gaaattaaat taccgattcc
     2341 gaaattaaac caaggaacaa ccagaacggc cggaaataaa attcctgtaa ccttcatggc
     2401 aaatgcttat ttggacaatc aatcgactta tattgtggaa gtacctatct tggaaaaaga
     2461 aaatcaaact gataaaccaa gtattctacc acaatttaaa aggaataaag cacaagaaaa
     2521 ctcaaaactt gatgaaaagg tagaagaacc aaagactagt gagaaggtag aaaaagaaaa
     2581 actttctgaa actgggaata gtactagtaa ttcaacgtta gaagaagttc ctacagtgga
     2641 tcctgtacaa gaaaaagtag caaaatttgc tgaaagttat gggatgaagc tagaaaatgt
     2701 cttgtttaat atggacggaa caattgaatt atatttacca tcgggagaag tcattaaaaa
     2761 gaatatggca gattttacag gagaagcacc tcaaggaaat ggtgaaaata aaccatctga
     2821 aaatggaaaa gtatctactg gaacagttga gaaccaacca acagaaaata aaccagcaga
     2881 ttctttacca gaggcaccaa acgaaaaacc tgtaaaacca gaaaactcaa cggataatgg
     2941 aatgttgaat ccagaaggga atgtggggag tgaccctatg ttagatccag cattagagga
     3001 agctccagca gtagatcctg tacaagaaaa attagaaaaa tttacagcta gttacggatt
     3061 aggtttagat agtgttatat tcaatatgga tggaacgatt gaattaagat tgccaagtgg
     3121 agaagtgata aaaaagaatt tatctgatct catagcgtaa ggaatagcag tagaaaaagt
     3181 ctgaatcaaa aatgaagttc tctcaaaagt tagaaataaa actctgactt tgggagaatt
     3241 tcattttatt attaatatat aaaatttctt gacat
//
LOCUS       DAVLZG010000097         3246 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLZG010000097 DAVLZG010000000
VERSION     DAVLZG010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.097"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            48..1535
                     /gene="tacF"
                     /locus_tag="VYO72_001957"
     CDS             48..1535
                     /gene="tacF"
                     /locus_tag="VYO72_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1708262.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            1545..2348
                     /locus_tag="VYO72_001958"
     CDS             1545..2348
                     /locus_tag="VYO72_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1708263.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            2350..3159
                     /locus_tag="VYO72_001959"
     CDS             2350..3159
                     /locus_tag="VYO72_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1708264.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         1000 a          612 c          542 g         1092 t
ORIGIN      
        1 ttcttattag ctaactttat gatataatga aaaacgaggt aaattgaatg aaaagtataa
       61 aattaaatgc tctatcttac atgggaattc gtgtcttgaa tattattttt cccatcctaa
      121 ctggaaccta tgtcgcgcgt gtcttggacc gaactgacta tggttacttc aactcagtcg
      181 acactatttt gtcatttttc ttgccctttg caacttatgg tgtctataac tacggtttaa
      241 gggctatcag taatgtcaag gataacaaaa aagatcttaa cagaaccttt tctagtcttt
      301 tttatttgtg catcgcttgt acgattttga ccactgctgt ctatatccta gcctatcctc
      361 tcttctttac tgataatcca atcgtcaaaa aggtctacct tgttatgggg attcaactca
      421 ttgcccagat tttttcaatc gaatgggtca atgaagctct ggaaaattac agttttctct
      481 tttacaaaac tgccttcatc cgtatcctga tgctggtctc tattttctta tttgttaaaa
      541 atgaacacga tattgttgtc tatacacttg tgatgagttt atcgacgctg attaactacc
      601 tgattagtta tttttggatt aaaagagaca tcaaacttgt taaaattcac ctaagtgatt
      661 ttaaaccact ctttctccct ctgacagcca tgttagtctt tgccaatgcc aatatgctct
      721 tcactttttt agatcgcctc ttcctcgtta aaacagggat tgatgtcaac gttagttact
      781 ataccatagc tcagcgaatt gtgaccgtta tagctggggt tgtaacaggt gcaattggag
      841 tgagtgtgcc tcgtctcagt tactatctgg ggaaaggaga caaagaagcc tatgtttctc
      901 tggttaatag aggtagtcga atctttaact tctttatcat tccactgagt tttggactca
      961 tggttttagg accaaatgcc atcctacttt acggtagtga aaaatatatc ggaggcggca
     1021 tcttgacctc tctcttcgct tttcgtacga ttatcctggc cttagatacc attcttggtt
     1081 cccaaattct ctttaccaat ggctatgaaa aacgtatcac agtctataca gtctttgctg
     1141 ggctactcaa tttgggcttg aatagtctcc tctttttcaa ccatatcgtg gctcctgaat
     1201 actacttact gacaactatg ttatcagaga cttctctact tgttttctat atcattttca
     1261 tccatagaaa acaactcatc cacttgggac atatctttag ctatactgtt cgatactctc
     1321 tcttttcact ttcctttgta gcaatttatt tcctgattaa tttcatgtat cctgtggata
     1381 tggtcattaa tttgccattt ttgattaata ctggtttgat tgtcttgcta tcagctatct
     1441 cttatattag tctacttgtc ttcacaaaag atagcatttt ctatgaattt ttaaaccatg
     1501 tcctagcctt aaaaaataaa tttaaaaaat cttaggagtt taaaatgaaa caactaaccg
     1561 ttgaagatgc caaacaaatt gaattagaaa ttttgaatta tattgatact ctctgtaaaa
     1621 agcacaatat caactatatt attaactacg gtactctgat tggggcggtt cgacatgagg
     1681 gctttatccc ttgggacgac gatattgatt tatccatgcc tagagaagac taccaacgat
     1741 ttattaacat ttttcaaaag gaaaaaagca agtataagct cctatcctta gaaactgata
     1801 agaactactt taacaacttt atcaagataa ccgacagtac aactaaaatt attgatactc
     1861 gaaatacaaa aacctatgag tctggtatct ttatcgatat tttccctata gatcgctttg
     1921 atgatcctaa ggtcattgat acttgttata aactggaaag cttcaaactg ctgtctttca
     1981 gtaaacataa aaatattgtc tataaggata gccttttaaa agattggata cgaacagcct
     2041 tttggttgct ccttcgaccg gtttctcctc gttattttgc aaataaaatc gagaaagaaa
     2101 ttcaaaaata tagtcgtgaa aatgggcagt atatggcttt tattccttca aaatttaagg
     2161 aaaaggaagt cttcccaagt ggtacctttg ataaaacaat cgatttaccc tttgagaatt
     2221 taagccttcc tgcacctgaa aaatttgata ctattttgac acaattttat ggagattata
     2281 tgaccctacc accagaagaa aaacgcttct acagtcatga atttcacgct tataaattgg
     2341 aggattagga tgcaatattt agaaaaaaaa gaaattaaag aaattcaact agccctgctg
     2401 gactatattg atgagacttg taagaaacat gatattcctt attttctcag ttatggaacc
     2461 atgcttggag ccatccgcca caaaggtatg attccttggg atgatgatat tgatatttcc
     2521 ctttatcgtg aggattatga gcgtttactg aagattattg aagaagaaaa tcaccctcgc
     2581 tacaaggttc tttcctacga tacatcttct tggtacttcc ataatttcgc atcgattttg
     2641 gacacttcta ctgttataga agaccatgtt aagtacaagc gtcatgatac cagccttttc
     2701 atcgatgtct tcccaattga tcgatttaca gacttgagca ttgtcgacaa gagctataag
     2761 tatgtggctc ttcgtcaact agcttatatc aaaaaatcac gagcagttca cggtgatagc
     2821 aaactaaaag attttcttag attatgtagc tggtacgctc tccgatttgt caatcctcgc
     2881 tacttttaca agaaaattga tcaactagtc aaaaatgctg taaccaacac tcctcaatat
     2941 gaaggaggag ttgggatcgg taaggaaggg atgaaagaaa tcttcccagt tgataccttt
     3001 aaagaactga ttttaactga gtttgagggc cgtatgttgc ctgttcccaa aaaatatgac
     3061 caatttttaa cccagatgta tggcgattat atgacaccac catcaaaaga aatgcaagag
     3121 tggtatagtc atagcattaa agcttatcgc aaaaactgat tgaggggtat tatacaaact
     3181 actaagatag aggttattca aaaacataat tttagtagaa aatgaaatac atattcccac
     3241 aataaa
//
LOCUS       DAVLZG010000098         3225 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLZG010000098 DAVLZG010000000
VERSION     DAVLZG010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3225
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.098"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            27..221
                     /locus_tag="VYO72_001960"
     CDS             27..221
                     /locus_tag="VYO72_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1708265.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(587..1897)
                     /locus_tag="VYO72_001961"
     CDS             complement(587..1897)
                     /locus_tag="VYO72_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1708266.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2134..3006
                     /locus_tag="VYO72_001962"
     CDS             2134..3006
                     /locus_tag="VYO72_001962"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1708267.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3137..>3225
                     /locus_tag="VYO72_001963"
     CDS             3137..>3225
                     /locus_tag="VYO72_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1708268.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQ"
BASE COUNT         1001 a          533 c          727 g          964 t
ORIGIN      
        1 tttatttttc attacgaata atatagatga aggggaaaga gtatgaaaac agaactgttt
       61 cttttgctat tagttcaaaa ggagaaaaaa tgaaagtaga aaatatttcg tatagggtgg
      121 atcatcgtat attgtttgat aatatttctt ttgatacttc gagttcaggc gtgacattaa
      181 ttactggtaa aaatggtaca ggaaagtcaa ctttactata gtagattgaa actagaatag
      241 tacacatcta cttctaaaat attgttagaa atcgatttga ctatcctgat ctatttgtcc
      301 tgttcttatt tcatttcact acatctcaaa ttgagtatga cgaagtgcgc tcccatgtcc
      361 tgggaacgca ctttcttcat atttttcata ttcttgaatc catcgataaa gactattggg
      421 atgaattttt aaagttgaac taatcatttt tacaggatga ggtttacagc agagagtttg
      481 aaggctttat caaaggtttt tcttggcata atgacttttc ctcgtttcca cttaattttg
      541 tgtctacttt attataccaa gtccaccctt aagttagata ataaatctaa cttaaggaag
      601 ctagaaggat gagaatccag gtggtcaaga gtcccaaact taagctgatg gggacaccca
      661 gaataatttg ctttttgaag gcaaggccac gttcctctat attgggaagt gagagttgaa
      721 tgagagaacc agctgatgaa aagggtgaga tattagtaga tagagcgcca ataacggtgg
      781 ctgttgtgag taagtgaata tcaatctggg gattttgagc actgatgata gcaatgatgg
      841 gaaagagggc tggagctaca acggataggg tggaactaaa gagtgacatc actccggcta
      901 tcacacaaaa gaacagaggt aaccagaaat gaggaatgga tgttgtcatg aggtgcccta
      961 tcagtgtgac taaacctgac ttgaccgcta gagacattag taagctcatg ccgcagagca
     1021 tgataattgt agcccaggga accttagcta aaatggcttc ttgcttccct aatttgagcc
     1081 ttaaggcgag gcagaccatg agtattgaga caaagccaat atcaaatgtt ttttgataag
     1141 tagctatcca ggcgatgttt gggaaaatga gatgcaacaa gggaaaaagc caaaccaaaa
     1201 ccatgctgct gatcatgagc aaggtggttt gtctttgaac cttgctgagg agtggtggtt
     1261 ggtcaatagt caaggatgag tttgtttttc ccttactata gtgactgtaa caggataata
     1321 aaagcaagac gatgagtggg tagataatgc tgacgataaa gatatgattg ccaagtgaaa
     1381 aagcttgctc ttcccatccc atttgcttaa acaggccttg aaagacaatg cctgagctac
     1441 tggttatcaa attagcccct cctgaagctc cccaattgac ggcttgagct ccaatcaaag
     1501 ggtgtttgtc cgctttttga cagagggtaa tcgctagagg acagcaaacg gccatagtag
     1561 tgaaaaatcc agcacctaaa gcagacaaaa gggttgccat caggtataaa atcatgtaga
     1621 gggcgttagg gtaggtgcgt gtgcggtaga gaatgtgttg agccaaaaca tcaagagtac
     1681 cgttagttat tgcaaagtta taaaagagag agacgctaaa aatggtaaaa aagagtgagg
     1741 ttggccaaaa atgaagaagt tctttggggc ttaatcccat gagagtggtt gcgatgaggt
     1801 aagaaaaagc aatagccagc aggccaatat tgattttggt gcggtaacca attccaatgg
     1861 ctagagcaat ggcgctaatc attattaaat gaatcattga attgtccttt cagttagaat
     1921 atggaaatag gttggcaatt ttggcgctca aaagaccacc tgtttcctat tggtacttga
     1981 ctattataca caaaaaaaat acaattgtct tgacaattgt attgacactt gttagaatta
     2041 aaaatgaggt attcaggctt gtgatttcct atggaagtta atagtgattg cctctaatgc
     2101 ttacaagtga tattaaaaat agaggactta gtgatgtcaa tcatttcaac tgatttaacc
     2161 ccttttcaaa tagatgatac attgaaagca gccttgcgag aagatgttca ttccgaagat
     2221 tacagtacca atgccatttt tgatcatcat ggccaagcca aggtgtcgct ttttgccaag
     2281 gaagctggtg ttttagcggg gctaaccgtt tttaaaaggg tttttaccct atttgatgcc
     2341 gaggtgacct tccagaatcc tcatcaattt aaggatgggg atcgtttgac tagtggcgat
     2401 ttggttttag aaatcatagg ctcggtgaga agtctcttaa catgtgaacg cgttgccttg
     2461 aattttttac aacatttatc agggattgct tcgatgacag ctgcttatgt agaagcctta
     2521 gacgatgatt gcattaaggt atttgatact cgaaaaacta ctcctaattt acgtcttttt
     2581 gagaaatatg ccgtgagagt tggcggtggc tataatcatc gctttaattt atcagatgct
     2641 atcatgctaa aagacaatca cattgcggca gtaggtagtg ttcaaaaggc aattgctcaa
     2701 gcgcgtgcct atgctccttt tgtgaaaatg gtcgaggtgg aagtggaaag ccttgctgct
     2761 gccgaagaag ctgcggcggc gggtgctgat attatcatgt tggataatat gtcattggaa
     2821 cagattgaac aggccattac cctaattgca ggacgttctc ggattgaatg ttctggaaat
     2881 attgatatga ccactattag ccgttttcgt ggtttagcga ttgattacgt ctccagtggt
     2941 agtttaaccc atagtgctaa gagtcttgat ttttccatga aggggttaac ctaccttgat
     3001 gtctaagttg taaaataaac taacttttta aaggatgtct ttcctctaga acgagtttta
     3061 tgtcagatag tttaaacgcc tcttcaaata tagtaaaatg aaccaaaaat agtacacaat
     3121 gtggtataat cttcttatgg catattcaat agattttcgt aaaaaagttc tctcttattg
     3181 tgagcgaaca ggtagtataa cagaagcatc acacgttttc caaat
//
LOCUS       DAVLZG010000099         3178 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLZG010000099 DAVLZG010000000
VERSION     DAVLZG010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.099"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            323..1609
                     /locus_tag="VYO72_001964"
     CDS             323..1609
                     /locus_tag="VYO72_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1708269.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     TLIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1624..1935
                     /locus_tag="VYO72_001965"
     CDS             1624..1935
                     /locus_tag="VYO72_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708270.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2170..2898
                     /locus_tag="VYO72_001966"
                     /pseudo
     CDS             2170..2898
                     /locus_tag="VYO72_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
BASE COUNT          996 a          547 c          682 g          953 t
ORIGIN      
        1 tatcagaata ataaataaaa aagcgatatt ctagactgta tcaatccttt tccattatag
       61 gagcaacaga gtgggagtag tcatctaagg actaatttat gtatttttac gagtcagtat
      121 ctttggatac tggtttttac ttttctagac tttttgacta cttgttaaaa ctgggataat
      181 tttcgactgt ttaacagtta ttatgcaaag tctaaaagat tagaattgtc aaaacaatcc
      241 gtctaggctt gattttatcc tttatttact ataaaatgag aaggaaaaat gtcaaacttt
      301 tatattgcaa ataggagaaa ttatgacaaa aacattaaaa cgtcctgagg ttttatcacc
      361 tgcagggact ttagagaagc taaaggtagc tgttcagtat ggagcagatg ctgtctttat
      421 cggtggtcag gcctatggtc ttcgtagccg tgcgggaaac tttactttcg aacagatgga
      481 agaaggcgtg cagtttgcgg ccaagtatgg tgccaaggtc tatgtagcgg ctaatatggt
      541 tatgcacgaa ggaaatgaag ctggtgctgg tgagtggttc cgtaaactgc gtgatatcgg
      601 gattgcagca gttatcgtat ctgacccaac cttgattatg attgcagcga ctgaagcacc
      661 aggccttgaa atccaccttt ctacccaagc cagtgccact aactatgaaa cccttgagtt
      721 ctggaaagag ctaggcttga ctcgtgtcgt tttagcgcgt gaggtttcaa tggaagaatt
      781 agctgaaatc cgcaaacgta cagatgttga aattgaagcc tttgtccatg gagctatgtg
      841 tatttcatac tctggacgtt gtactctttc aaaccacatg agtatgcgtg atgccaaccg
      901 tggtggatgt tctcagtcat gccgttggaa atacgacctt tacgacatgc catttgggaa
      961 agaacgtaag agtttgcagg gtgagattcc agaagaattt tcaatgtcag ccgttgacat
     1021 gtctatgatt gaccacattc cagatatgat tgaaaatggt gtggacagtc taaaaatcga
     1081 aggacgtatg aagtctattc actacgtatc aacagtaacc aactgctaca aggcggctgt
     1141 ggatgcctat cttgaaagtc ctgaaaagtt tgaagctatc aaacaagact tggtggacga
     1201 gatgtggaag gttgcccaac gtgaactggc tacaggattt tactatggta caccatctga
     1261 aaatgagcag ttgtttggtg ctcgccgtaa aattcctgag tacaagtttg tcgctgaagt
     1321 ggtttcttat gatgatgcgg cacaaacagc aacaattcgt caacgaaatg tcattaacga
     1381 aggggaccaa gttgagtttt atggtccagg tttccgtcat tttgaaacct atattgaaga
     1441 tttgcatgat gccaaaggca ataaaatcga ccgcgctcca aatccaatgg aactattgac
     1501 tattaaggtg cctcaacccg ttcaatcagg agacatggtt cgtgcattaa aagaaggact
     1561 catcaatctt tataaggaag atggaaccag cgtcacagtt cgagcttaag aaaggaaaag
     1621 gaaatgatag aggcacaggg tttcttagtg gataagcaaa caagatgcat tcattaccat
     1681 agcaagctgg atattattgc tttacaatgc tatgattgta aaaagtatta tgcttgttat
     1741 cggtgtcatg attcattaga aaatcaccct tttgagccgt atcccttatc tttgatacag
     1801 gataagccta ttttatgtgg tgtttgtcta aaactactaa catataagca atataaagaa
     1861 agcttaagtt gccccttttg tttttctcgc tttaatccag gttgccaaaa tcataaggaa
     1921 cgctatttta aatagcaaat catctagttt tgaagtagga gaaaactcaa ttccaagaga
     1981 aaatgaagta aatcttccca caataaaacg cataatatca agattgttca atacctgata
     2041 ctatgcgttt ttaagatttt aaagactttt ttcctttatc tggtattttg actacttgtt
     2101 aaaactgggt taattttcaa ctgtttaaca gttattatgc aaagtctaaa agattagaat
     2161 tgcgtctaga gtatgcgtga tgccaaccgt ggtggatgtt ctcagtcatg ccgttggaaa
     2221 tacgaccttt acgatatggc atttgggaaa gaacgtaaga gtttgcaggg tgagattcca
     2281 gaagaatttt caatgtcagc cgttgacatg tctatgattg accacattcc agatatgatt
     2341 gaaaatggtg tggacagtct aaaaatcgaa ggacgtatga agtctattca ctacgtatca
     2401 acagtaacca actgctacaa ggcggctgtg gatgcctatc ttgaaagtcc tgaaaagttt
     2461 gaagctatca aacaagactt ggtggacgag atgtggaagg ttgcccaacg tgaactggtt
     2521 acaggatttt actatggtac accatctgaa aatgagcagt tgtttggtgc tcgtcgtaaa
     2581 attcctgagt acaagtttgt cgctgaagtg gtttcttatg atgatgcgac acaaacagca
     2641 accattcgtc aacggaacgt cattaacgaa ggggaccaag ttgagtttta tggtccaggt
     2701 ttccgtcatt ttgaaaccta tattgaagat ttgcatgatg ccaaaggaaa taaaatcgac
     2761 cgcgctccaa atccaatgga actattgact attaaagtcc cacaacctgt tcaagctgga
     2821 gacatggttc gagctcttaa agaggggctt atcaatcttt ataaggaaga tggaaccagc
     2881 gtcacagttc gtgcttaatg tagttgttta gttttaaaaa attatgcaaa gctccatata
     2941 caacacttaa acgagattaa agaatggcga aatcccctga tgcgcaagag attagctgtc
     3001 ttttttattt tttaagtgat aaagtcggag cttaggtatc aaagcctatc aaattaaaca
     3061 aagaagcgat gtcttagata ttttgaaaaa aattaataag cagaaaactc tctattattt
     3121 tgttgtatag agttttttgt taataaaatt tcacaaaatg acatttatat attgcatt
//
LOCUS       DAVLZG010000100         3110 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLZG010000100 DAVLZG010000000
VERSION     DAVLZG010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3110
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.100"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(293..826)
                     /locus_tag="VYO72_001967"
     CDS             complement(293..826)
                     /locus_tag="VYO72_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1708271.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(915..1691)
                     /gene="recX"
                     /locus_tag="VYO72_001968"
     CDS             complement(915..1691)
                     /gene="recX"
                     /locus_tag="VYO72_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1708272.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1729..3084
                     /gene="rlmD"
                     /locus_tag="VYO72_001969"
     CDS             1729..3084
                     /gene="rlmD"
                     /locus_tag="VYO72_001969"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1708273.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          993 a          547 c          555 g         1015 t
ORIGIN      
        1 aatacaaaaa aatgtttttg atacgaagtt gacctgtatt ttttatacta atcattttcg
       61 tattttttgt attaaacgat ataagtttgt tgtaaactta ctaggaataa agacattaaa
      121 aaataatagt atatctattt gttttatata ttttacgaat tctgcataaa tctctttcta
      181 gtaatgtgtt gtaactctgc tataatggat ttattccttt ttgtgtttac acaatttatt
      241 ttatactacc aaaaaaacaa ggtcaggatt ttgttcctga cctttgacaa ctttaccgat
      301 tctttagttc tacatagcgc ttgtaccaaa tgtttacata ggcttctgag aaaggaccac
      361 gtccattgtt aatccaatca acaagaattt tgacatgttc ttttaaaata tagtccaagt
      421 catcagaata attcattttg cgtttgtgac gctcgtattc ttcaacgtcc aagagacgtt
      481 tttccccatc tgtaaaaatt ttaacatcca aatcgtaatc aatatacttc agtgcttctt
      541 catccagata gtaggggcta gccatattgc aatagtaaga agttccatta tcacgaatca
      601 tggcaatgat attaaaccaa tatttcttgt gaaagtaaac aatagccggt tctcgagtga
      661 cccaacgacg accatcactt tcggtaacaa gtgtatgatc gttgacacca ataatggcgt
      721 tttctgttgt ttttagtacc atggtgtccc gccaagttcg gtggagactc ccatcatgct
      781 tataactttg aattgtaata aagtcgcctt cttttggaag cttcataact aaccaacttt
      841 ctacaattta taagtttatc atttactatt gtaccataaa attacctaaa atctgtgaat
      901 ttcacttgga aatattaaag atattctcta agagcgcttg ctatatccga aaaatcgtag
      961 ccctttcgtg ctaaaacttg agttaaacgc tgcttcagtt cgtatccttc atactttcgg
     1021 gcatacttag tatattgctt atcaagttcc ttgaagatga gttcctgagt cgtttcttgg
     1081 tcaacttgac tatccaattc gtcaaaggca attttagcat caaaataaga gaagcccttg
     1141 ttagtcaagt tctggataat cttatcttgc agggcacgag ctggaagttt tccctcatat
     1201 tttttcaata gtttattggc tacacgttga gcaacttccg aaaaatcaaa atcattcaag
     1261 atttcttcta tagtagattt tgaaattcct ttttgtgcta atttctgagt cagtacataa
     1321 ggtcccttgt ctcctgaaac ttgattggca ttgatgatag cataagcgta ctgaccatca
     1381 ttaatccact tatcttcttt aagattagca ataacttgag aaacgatgtt tttatcaata
     1441 tcgtattttt tcagatattc tctgacttct ttttcagtgc gtgctttaaa ggataagtgg
     1501 tagagggcca gattcttacc ataagaaaat tgagcaaagt cttgaatctc tttcaattcc
     1561 tcttcgctta tcaccttatc tctcgataac ataaaacgaa caattgtatc ttcggtgata
     1621 tagcatttgt cgccattatc aagctccatc agatagagtc tttttttctt ttcaagtttt
     1681 gtgattttca tagctctatt ataactcaaa atgtgataag ataggggtat gaatctgaaa
     1741 gtgaaacaaa aaataccatt aaaaatcaag cgcatgggaa ttaacggtga gggaatcggc
     1801 ttttaccaaa aaacattagt ctttgtacct ggagctctca aaggcgaaga tatctattgt
     1861 cagattactt ctattagacg caactttgtt gaagcaaaat tactgaaggt caacaagaag
     1921 tctaaatttc gaattgtgcc atcttgtact atttataatg aatgcggagg ctgccaaatc
     1981 atgcacctgc attatgataa gcagctggag ttcaagacgg acttacttca tcaagcgctg
     2041 aaaaaatttg ctcctgcagg atatgaaaat tatgaaattc gtccaactat tggaatgcag
     2101 gaaccaaaat attacagagc taagttacaa tttcagactc gaaaatttaa aaatcaggtc
     2161 aaggcgggct tatatgcaca aaactctcac tatttagtag agttgaaaga ctgcctggta
     2221 caagataagg aaacccaagt gattgctaat cgcttagcag aattacttac ttatcaccag
     2281 attccaatca cggatgagag aaaagttcta ggtgtccgta ctattatggt ccgacgcgcg
     2341 agaaagaccg gacaggttca gattattatt gttacaaacc gccagcttaa tttaactcaa
     2401 ttggtaaaag agttggttaa agatttccca gaagttgtga cagtagctgt taatacaaat
     2461 acagctaaaa ccagtgagat atatggtgaa aagacagaga ttatctgggg gcaagagagt
     2521 attcaagaag gtgtactcaa ttatgaattt tcactatccc ctcgagcttt ttatcaacta
     2581 aatcctgagc aaacagaagt cctctatagc gaagcagtaa aagcgctgga tgttgataaa
     2641 gaagaccatt tgattgacgc ttattgtgga gttggaacga ttggatttgc ctttgcaaag
     2701 aaagtaaaaa cactcagagg tatggatatt attccagaag ctattgaaga tgccaagcga
     2761 aatgctaaaa gaatgggatt tgacaatact cattatgaag ctggaacggc agaagagatt
     2821 attcctcgtt ggtacaagga aggctaccga gcagatgctt tgattgttga cccaccacgt
     2881 acaggtctgg atgataagtt attagatact attcttactt atgtaccaga aaaaatggtt
     2941 tatatttctt gtaatgtttc gaccttggct cgtgatttgg tacgcttagt agaagtctat
     3001 gatcttcatt atatccagtc ggtcgatatg ttcccacata cagctcgaac tgaagctgtt
     3061 gtaaaattaa taaaaaaagt ttaaaaaagt agttgacaaa gtttgaaaag
//
LOCUS       DAVLZG010000101         3062 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLZG010000101 DAVLZG010000000
VERSION     DAVLZG010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.101"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..1022
                     /locus_tag="VYO72_001970"
     CDS             <1..1022
                     /locus_tag="VYO72_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1708274.1"
                     /translation="NKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAF
                     GQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKELN
                     GKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLW
                     RDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTS
                     KFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITYGD
                     DKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNA
                     CKNAK"
     gene            1012..2019
                     /locus_tag="VYO72_001971"
     CDS             1012..2019
                     /locus_tag="VYO72_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1708275.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2019..3026
                     /locus_tag="VYO72_001972"
     CDS             2019..3026
                     /locus_tag="VYO72_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1708276.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
BASE COUNT         1043 a          438 c          533 g         1048 t
ORIGIN      
        1 aaaacaaatt ttttctaata gctattttag ctatgtgtat agtttttagc gcttgttctt
       61 ctaattctgt taaaaatgaa gaaaatactt ctaaagagca tgcgcctgat aaaatagttt
      121 tagatcatgc tttcggtcaa actatattag ataaaaaacc tgaaagagtt gcaactattg
      181 cttggggaaa tcatgatgta gcattagctt taggaatagt tcctgttgga ttttcaaaag
      241 caaattacgg tgtaagtgct gataaaggag ttttaccatg gacagaagaa aaaatcaaag
      301 aactaaatgg taaagctaac ctatttgacg atttggatgg acttaacttt gaagcaatat
      361 caaattctaa accagatgtt atcttagcag gttattctgg tataactaaa gaagattatg
      421 acactctatc aaaaattgct cctgtagcag catacaaatc taaaccttgg caaactttat
      481 ggagagatat gattaaaatt gattcaaaag ccttaggtat ggaaaaagaa ggtgatgagt
      541 taatcaaaaa tactgaagct cgtatatcca aagaattaga aaaacatcca gaaatcaaag
      601 gaaaaatcaa aggaaaaaaa gtattattta ctatgattaa tgctgcagat acatcaaaat
      661 tctggattta tactagcaaa gatccaagag caaattattt aacagattta ggtctagttt
      721 tccctgaatc attaaaagaa tttgagagtg aagatagttt tgcaaaggaa atttctgcag
      781 aagaagcaaa taagataaat gatgctgatg taatcataac ttatggtgat gataaaactc
      841 ttgaagcttt acaaaaagat cctcttttag gtaaaataaa tgcaattaaa aatggtgccg
      901 ttgctgtaat tccagataat acaccgttag cagcctcatg cactccaaca ccactttcaa
      961 taaactatac tattgaagaa tatctaaatc ttttaggaaa tgcatgcaaa aatgcgaaat
     1021 aaaaaacaaa taaacctagg cataattttt gtaatctgcc taggtcttct tattacaata
     1081 tttttgtcat taaagcttgg aacaaaagaa attaatatca gagatttttt agcagctttt
     1141 ggaatgggta atacaaatga tgattttatt aaatcaatta tatataaaag aatacctaga
     1201 actatttttg caattttagc aggttctagt cttgccataa gcggtgtatt gatgcaatca
     1261 gttactagaa acccaatagc tgatccaggt atactcggta taaacacagg agcaagtctt
     1321 agtgtagtaa ttggtctttc ttttttagga atttcatcaa gcataagcca tataagtttt
     1381 gcaatcattg gtggcttagt aagtgcaatt tttgtatacg cgattgctgt aagcggaaaa
     1441 gcaggcctta cccctataaa acttgcctta tcaggaactt gtgttagtat ggctttaagc
     1501 agttttgtaa gttttttaat tttaccgaat aataacgtct tagacaaatt tagattttgg
     1561 caaataggta gccttggagc agctacatta tcttctatat ctacactact accttttata
     1621 attttaggtc acttgatagc tatatttatt tcatcagatt taaacgcttt agctatgggt
     1681 gatgaaatgg ctgttggtct tggagttaat gttaatagga taagatcact tgcaataatt
     1741 gcaagtgtgc ttttatgttc aagtattact gcaattggtg gacctattgg cttcgtaggt
     1801 cttatagttc ctcacttttg tggcttattt ataagcaaag atatacgcac aatgaccatt
     1861 tcttcatctt ttataggtgc agagctcttg cttatatgtg atataatcgg ccgtatgtta
     1921 ggtaaaccag gtgaaattga agtagggata attactgcaa taatcggggg tccagtactt
     1981 atttatgtaa ctatgaaaaa tagaggggtt aataactaat gcaaaattta attataggta
     2041 ttcaaaaaag aaaaaataga ataacactat tttcctcact atttttatta ataataatca
     2101 gtctatcatt tttcatttta cttatcggag atgaaagtta ttctttttca actttgatta
     2161 aagtcttaaa tagtgaaact gttcctggag ctagtttttc gattatggaa attagattac
     2221 caaaattatt agcaggaatt atagctggct ggtcttttgg attggcagga tttatctttc
     2281 aaactatgtt aagaaatcct cttgcaagtc ctgatataat cggtgtcaca agttcttcat
     2341 ctattgcagc ggtcttttgc atattggtat taaaaacaaa tagtttaact actggaatta
     2401 tttcaataac ttgtggacta acatcatctt taatattatt tttactagct aaaaaagatg
     2461 gtttttcagc agcaagactg ataatattag gtattggttt tcaagctgtc acaagagcag
     2521 gcacctcatt tttattgttg aaagtagcaa gatatgaatt acaagaagtt atgagatggc
     2581 tcagtggctc tttatctttt acaaagttag atgacatacc tcttgttcta atagtaagta
     2641 ttattgctac tatattagtt ttatttttta ataaaagact agaaattatt gaacttggtg
     2701 aagaaatagc aatcggactt ggagcaaatc ccgagctttc aaggcttgtt ttaatttttt
     2761 gcgctgtatc tttaactgct ttttctactt caattacagg accaatagct tgtatatctt
     2821 ttttagctgg tcccatagcc ttaaatattg gcaagaaaag aagcccaata ttagctggat
     2881 tggttggaat tttactagtt ttgttatcag acatattctc tcaaaatatt ttaccagcta
     2941 gatatccagt aggtgttgta actggcttgt taggttcacc atacttaata tacttactaa
     3001 taaaaatgaa caggaggaat atataatgaa aggtctgtgg tcaaataatc ttacctgcgg
     3061 tt
//
LOCUS       DAVLZG010000102         2929 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLZG010000102 DAVLZG010000000
VERSION     DAVLZG010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.102"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            362..838
                     /locus_tag="VYO72_001973"
     CDS             362..838
                     /locus_tag="VYO72_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1708277.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            838..1614
                     /locus_tag="VYO72_001974"
     CDS             838..1614
                     /locus_tag="VYO72_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1708278.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQSIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQENGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNPARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEERMRDMSKSNGKDA"
     gene            1598..2407
                     /locus_tag="VYO72_001975"
     CDS             1598..2407
                     /locus_tag="VYO72_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HEV1708279.1"
                     /translation="MEKMHSYIKYLTQEDPIITDEGKQIEILHLDIQDDPEIFEDWAK
                     QFRRNYCSDDELAEMIGFMNISPKEYLENFKLPSDSGIGLSTMSGDFGEILVSDYLQY
                     IEEYVVPRTRYDSKVNKNTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSKA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQANVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKNHRDFQKLRLLVIHSNELMKFIRELYSKASEV"
     gene            2404..>2929
                     /locus_tag="VYO72_001976"
     CDS             2404..>2929
                     /locus_tag="VYO72_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence associated protein"
                     /protein_id="HEV1708280.1"
                     /translation="MIEFGRRSLYFSKLVRSKAKMIEFDIPLESHLPISEDAQKSFLG
                     ALAIVADTARKYFEVYINRKSFNLQLKNQLHNAAEYFDALLVSGLGNSAEYQDYIAIL
                     GTTAYYLCDYNGSSRVMINYISDDIQLLEDCMTLIKVFIDVVTDELFLNHTPIEGKYS
                     SELNTLVESYRNYIL"
BASE COUNT         1056 a          390 c          565 g          918 t
ORIGIN      
        1 aaaaacaaca ctttattgag gtattggata cgctttgcta atagcctaat aatcacatgt
       61 ggagtgttgc tacaacgaaa aaggtgataa tccttgattt caagctattt tataagcatt
      121 ttgtctttgt agataaaggc aattttgaca ataaaaatcc taaaaggtga atcgttatag
      181 atgtatttgt agatatcgtt tgcgcatcga aaaaattaat acaagaataa atatttatgg
      241 ctctttaggt gacttttata gaagtaaagt ttaggataga aaaacagtca ataacgcacc
      301 atttttggtg cgttatgctt ttttatgcta taatggattt ataaaaataa aggagtttgc
      361 catgattgga aaaaacataa aatccttacg taaaacacat gacttaacac aacacgaatt
      421 tgcacgaatt ataggaattt ctcgaaatag cttgagtcgt tatgaaaatg gaactagttc
      481 agtctctacg gaattaattg acatcatttg tcagaagttt aatgtatctt atgtcgatat
      541 tgtaggagaa gataaaatgc tcaatcctgt tgaagattat gaattgactt tgaaaattga
      601 aattgtgaaa gaaagaggtg ctaatctatt atctcgactc tatcgttatc aagatagtca
      661 gggaattagc attgatgatg aatctaatcc ttggatttta atgagtgatg atctatctga
      721 cttgattcag acaaatatct atttagtaga aaattttgat gaaatagaga gatatagcgg
      781 ctatttggat ggaattgaac gtatgttaga gatatctgaa aagcggatgg tagcttaatg
      841 gaaatccaag attatactga tagtgaattc aaacatgctt tagcaaggaa tcttcgttca
      901 ctgacaagag gaaaaaagtc cagtaaacaa tctatagcga ttttgcttgg aggtcaaagt
      961 ggtgccggta agactacaat tcatcgtatt aaacagaaag aatttcaagg aaatattgtt
     1021 atcatagatg gtgatagttt tcgttctcag catccacact atttagaact gcagcaagaa
     1081 aatggcaaag atagcgttga atacaccaaa gattttgcag ggaaaatggt agagtcttta
     1141 gtaaccgaat tgagtcattt gggatacaat cttttgatag agggaacttt acgaactatt
     1201 gatgttccaa agaaaacagc acaactatta aaaaataagg ggtatgaggt acaattagcc
     1261 ttaattgcaa ccaagcccga attgtcctat ctgagcaccc ttatccgata cgaagaactg
     1321 tatgctatca atccaaatcc agcacgcgca actccaaaag aacatcatga tttcattgta
     1381 aatcatctag ttgataatac acgacaattg gaagaactag ctatttttga aagaattcaa
     1441 atttaccaac gagatagaag ttgtgtatat gattcaaaag aaaatacaac ttcagcagca
     1501 gaagtgctac aagaatacct cttcggaaaa tggagcaagg tagaggaaga gatgttgaag
     1561 gtgggagaag aacggatgag ggatatgagt aaaagtaatg gaaaagatgc atagttatat
     1621 aaagtatcta actcaagaag atcctattat tactgatgaa ggtaagcaga ttgagattct
     1681 tcacttagat attcaagatg acccagaaat ttttgaagat tgggcaaaac aattcagaag
     1741 aaattattgt tctgatgatg aacttgctga aatgataggt tttatgaata tctcccctaa
     1801 agagtatctt gaaaatttta aattaccctc ggatagtggt attggccttt caacgatgtc
     1861 aggagatttt ggagaaatat tagtatctga ttatcttcag tatattgaag aatatgtggt
     1921 tcctaggact cgttatgata gtaaagtcaa taaaaatact tcaactcaag gaagtgatgt
     1981 tctaggatat aagcaagatt cttcgaatgt gtcgaatgat gaggttgtag ttattgaagt
     2041 aaaatcatct gcatcagatt ctagtagctc taaagcgaaa aataagcttc aagaagctat
     2101 taatcattct gataaagatt ttgaacgatt ttcaacctca attgtagcca gctatttgag
     2161 gttaaagaaa tctaatagtg atcaagcaaa tgtagtagaa agatttttaa acataacgga
     2221 taaaccgttt aatgtaatct atggagctgt tgcagtctac tccaatcaat catatgatat
     2281 tgatgttatc aagacagtag tttcaaaaaa tcacagagat tttcagaaat tacgactatt
     2341 ggtcattcat tctaatgaat taatgaaatt tattagagaa ctctattcga aagcgagtga
     2401 ggtatgatag aatttgggag aaggtcatta tatttttcaa aattagtgcg ttcaaaggca
     2461 aagatgattg aatttgatat tcctttagaa agtcatttac caatttcaga ggatgctcaa
     2521 aaatcgtttc ttggggcact agcaattgtt gcagatactg ctaggaagta ttttgaagtt
     2581 tatatcaatc gtaagagttt taatttacaa ttaaaaaatc aattacacaa tgctgctgaa
     2641 tattttgatg cattgctggt gtcaggatta ggaaattcag ctgaatatca agactatatt
     2701 gcaatattgg gtaccacagc ttattatcta tgcgattata atggtagttc gagagttatg
     2761 attaactata tatcggatga tatccagtta ttagaagact gtatgactct tataaaagta
     2821 tttattgacg ttgtaacgga tgaactcttt ttgaatcata cgccaataga aggtaaatac
     2881 tctagtgagt taaatactct agttgaatca tatagaaatt atattttat
//
LOCUS       DAVLZG010000103         2802 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLZG010000103 DAVLZG010000000
VERSION     DAVLZG010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.103"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..422)
                     /locus_tag="VYO72_001977"
     CDS             complement(<1..422)
                     /locus_tag="VYO72_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708281.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSDDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYP"
     gene            complement(436..1149)
                     /locus_tag="VYO72_001978"
     CDS             complement(436..1149)
                     /locus_tag="VYO72_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1708282.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1608..1988)
                     /locus_tag="VYO72_001979"
     CDS             complement(1608..1988)
                     /locus_tag="VYO72_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1708283.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2410..>2802)
                     /locus_tag="VYO72_001980"
     CDS             complement(2410..>2802)
                     /locus_tag="VYO72_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1708284.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          856 a          543 c          444 g          959 t
ORIGIN      
        1 ggataatact ctttaatatt attaactttt tgttcgtagg catattttgc tacatgatct
       61 aggtatatat caaaaaagtc atgaggaaaa tctcccatac agccattacg attcatattg
      121 aggctatatt ttcgattagt aagataattc ggaaatatat ttcctattac tctaagatta
      181 tctacttgtg aatcccttct cccaatataa tccccttctt tgactaatga tggagatttc
      241 caagtaaaaa ttaaatcgtc agagaaattt ttcttatcaa aaaacttaaa aagagattga
      301 taaatactat ttgctaattg acaagtgtca gatgtaaatt cataattaac agcttcatta
      361 aaatcaactt cagacatttc aatgtactct tcaatagtaa tattagcttt ttttgtagtc
      421 attagctaat ctcctttaaa atgtgatctt ttcaagaata tttttatcta aacaatccag
      481 caagtcttgg taagaataga cttcgtaagt cggctgggct tgtgtgtgat tttcgaggtg
      541 atgaggatta taccagatag tgtcaatccc cgcattattg ccaccttgaa tgtcggcggt
      601 tagagaatct ccaatcatca gcgtcttttc tttactaaat ccagcaattt gctggccaat
      661 cttttcataa aagagagcat ccggcttttg agtttgcaac tgttctgaga taaagacttg
      721 attgaaataa ggtactagac cagattgagc caaacgtcct gtctgaatgg cagtaatgcc
      781 atttgtcgca gcatacaagt tataatcacg ctcaatgagg ctgtccaaga gatcatgagc
      841 gcccgatagt gtttgtccct gctgagcgag ataaaattgg taacgctggg caagaaaact
      901 accgtctttt tcctgtccaa aatgagaaaa taaacgagaa aagcgcgtgt taaccagctc
      961 ttgtttactg attttcttca gctccaagtc tttccagaga gccttgttca taggaacgta
     1021 ataatcttta taagcctgaa tatccgcaac tccttcttct tttagaagtt gggtcaaagc
     1081 cacatcctca gcagcatcaa aatcaagaag agtgtggtcg aggtcgaaga gtagaaattt
     1141 gtagaacaat ttgaggtttt cctttctgaa aattcattaa gaacattata tcataaagca
     1201 cctcatacaa ttaactaatt taatcactta aaaaaaattc gaacactttc tatacaactg
     1261 acagctcaaa tctttcagaa tagaacaata ctaactatcg agcaccctgt cttcataaat
     1321 atatgtgtaa ttctagacct agaattccta taaactaaat gctttcatac tcttccaagt
     1381 aattgattgc cttaaatttt aatttttgaa ggattctaaa gctagaatag tcccatcaca
     1441 atcagttttg attgattcac aatttagaaa cactatagtt tcactcctgt taaaataaaa
     1501 aggaactgca taaagcaatc cctttctgat tttgaaatca tttacttaac attttatagt
     1561 tgagataatc aatagcttac ctataaaaag agttatagta aaattcctta tttattgatt
     1621 tcaagctccg ctaactgtgt ttgaataact gacagttctg caccagcctg aagaagagca
     1681 gctgcattat aggcaccttc tacaattgga accctgttga tgatgatact tttatcactg
     1741 aaatcagtca ccatttttaa gttcatttta gcagaaccta ggtcaaaaaa ggcaagtaaa
     1801 gtatctgctg gattttcgga aacaacccta tctacttgat caaaactcgt tccaattcct
     1861 ccgccctcgg ttcctcctac ataagtaatc ggaacatctt tagctacttt actaatcagt
     1921 tcaacaacac cttctgcaat gtgtttggaa tgtgaaacga taacaagacc aataccaata
     1981 ctttccatca aaccacccca gtttctaaaa tagcagtaaa gagtaatcct gatgagaatg
     2041 atccaggatc aatatgtcca agaaaccaca tgctcctaag acaagagcta acagactggc
     2101 catcaataat agtattgttc tttttttcat cattactcct taactagtgt ttaactgatc
     2161 aattagccag taaatagttt atctttattt acactatctg ttaagatata gtaaaatgaa
     2221 ataagaacag gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtatactatt
     2281 ctagtttcaa tctactatat tttgcacatt ttcatgaaaa aaatgagaac tagaactcac
     2341 attctgctct catttttcgt tttcccgttc tcctatcctg tttttaggag ttagaaaatg
     2401 ctgctacctt tacttactct cctttaataa agccaatagt ttttcagctt ctgccataat
     2461 agtattgttg tcctgggtgc caaatagtaa attatttttt aatcctgtga gagtctcttt
     2521 ggcattggac ttgataattg gatcctggat ttttccaagt aaatcttcag cctctctcag
     2581 tttttcttca accttttcag tctcgacctg aggttcttct gattcctctg gtgattcttc
     2641 ttctggttcc tctgttggtt ttggagactc tggtttctcg ctttgcggtt tctcttctcg
     2701 aggggtttct tcctcaggtt tttctgtctg aggtttctcc tcgcttggtt tttccgtttg
     2761 attggtatca gcttgaccat ttttgtttct ttgaacatgg tc
//
LOCUS       DAVLZG010000104         2737 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLZG010000104 DAVLZG010000000
VERSION     DAVLZG010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.104"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            129..1475
                     /gene="gdhA"
                     /locus_tag="VYO72_001981"
     CDS             129..1475
                     /gene="gdhA"
                     /locus_tag="VYO72_001981"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1708285.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(1981..2151)
                     /locus_tag="VYO72_001982"
     CDS             complement(1981..2151)
                     /locus_tag="VYO72_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708286.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2164..>2737)
                     /locus_tag="VYO72_001983"
     CDS             complement(2164..>2737)
                     /locus_tag="VYO72_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1708287.1"
                     /translation="KIPSGLYKIDTGKVLFDGININQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQIIVAHRLSTIKDADIIFV
                     MKGGKIVESGNHKYLMELGGEYYSLYTKRK"
BASE COUNT          871 a          519 c          461 g          886 t
ORIGIN      
        1 tattttcaaa aaaaaccaaa aactgaattg aaagaatttt tagaaaattt ctgttttttc
       61 tttacagtga aaaaaaattc tgctataatg tcttatgtaa taaaatatga caataaaagg
      121 agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact gtaaaagctc
      181 gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac actttggaac
      241 ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt attactgagc
      301 ctgagcgcgt gatttctttc cgtgttcctt gggttgaccg tgatggaaaa gttcaagtaa
      361 accgcggcta ccgtgttcaa ttcaactcag ctgttggacc atataaaggc ggacttcgtt
      421 tccacccaac tgtaaaccaa gggattttga aattcctcgg atttgaacaa atctttaaaa
      481 acgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc gatcctaaag
      541 gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa ttgcaaaaac
      601 acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga cgtgaaattg
      661 gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc ttgactggta
      721 aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac ggtttggttt
      781 actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag aaagtcgtta
      841 tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa agcaactgaa ctcggtgcaa
      901 ctgttatttc tgtttctgac tcaaatggtt atgtcatcga tgaaaatggt atcgacttcg
      961 atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt gactgagtat gcagctgaaa
     1021 aagcaactgc aacctaccac gaaggtactg tatggactta cgctggaaac tatgacattg
     1081 ctcttccatg tgccactcaa aacgaaatca acggtgaagc agctaaacgt ttggttgctc
     1141 aaggcgttat ctgtgtatct gaaggtgcca acatgccgag cgaccttgat gccatcaaag
     1201 tttacaaaga aaatggtatc ttctacggac ctgcaaaagc tgccaacgct ggtggtgtag
     1261 ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct ctcatggact cgtgaagaag
     1321 ttgatggcca tctcaaagac atcatgacaa acatcttcaa cacagctaaa acgacttcag
     1381 aaacatacgg tcttgataaa gactaccttg caggagctaa cattgctgcc tttgaaaatg
     1441 tagcaaatgc catgattgca caaggtattg tttaagattt atttactcaa tcctcaatca
     1501 ctacgattgg ggatttttag cttgaattaa aaaattggaa aatctaatta aataaaatga
     1561 aatgaaataa aaactgaaca aattgattgc ggaattcaaa ccaatttcta acatacttct
     1621 agaaattaat ttgacttttc taatcgattt gttcatatct tatttcaatt tactatactt
     1681 acttaaccct ttttatactc aatgaaaatc aaagagcaaa ctaggaagcg agccgcaggc
     1741 tgtacttgag tacggcaagg caaagctgac gtggtttgaa gagattttca aagagtatta
     1801 aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta atcatgtttt taagctacta
     1861 ctgtagttgc tctattattt aagtgttatg aataacttca atatctttaa agctttttgt
     1921 tagatttata atttcaacta tagccatctc tactccttag tttacagcaa aaaattatgc
     1981 ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat tcaacaagcc
     2041 taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaacacta ttccaatcat
     2101 cacccctagt gaggctgttg ttaaaattac atattcattt tctttcttca ttttctttac
     2161 acctcatttc ctttttgtat ataagctgta gtactctcca ccaagctcca ttaagtactt
     2221 atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat ccgcatcctt
     2281 aatcgttgac aatctatgag ctacaattat ttgagtacag ccctgacttt ttatatactt
     2341 tgttattctt tcctcattaa tagtgtctaa agcactagtt gcttcatcta aaattacaat
     2401 actaggatta tttattaatg cacgtgccag tgctatccgt tgtctttgac cacctgaaat
     2461 atttgaaccc atctctgaga tgatagtatt aaatttcatc ggcatagcca tgatttcatc
     2521 atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt cgttctttaa
     2581 agttatatta tcaagaatac ttcggttcaa taaaaatgaa tcctgtggaa ctactcctaa
     2641 attttgactt aatatttttt tatctatttg attaatattt ataccatcaa ataaaacttt
     2701 tcctgtatca atcttatata atcctgatgg tattttt
//
LOCUS       DAVLZG010000105         2724 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLZG010000105 DAVLZG010000000
VERSION     DAVLZG010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.105"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            129..1622
                     /locus_tag="VYO72_001984"
     CDS             129..1622
                     /locus_tag="VYO72_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1708288.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..>2724
                     /locus_tag="VYO72_001985"
     CDS             1635..>2724
                     /locus_tag="VYO72_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1708289.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQFACEIAIKVWRNS"
BASE COUNT          976 a          412 c          524 g          812 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttctaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgttt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaaaggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     2221 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     2281 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     2341 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     2401 caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     2461 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcta aatcagaaat
     2521 ttattatcca tgttttaagg aataataatt atagtcgagt gatatcagga agtgctcagc
     2581 ctcagttacc aattacaaaa ttaaaaaaaa tacttctccc cctcccccca ctagccctcc
     2641 aaaatgagtt cgcagacttt gtagtccagg tcgacaaatc acaatttgct tgtgagatag
     2701 ctataaaagt gtggagaaat agct
//
LOCUS       DAVLZG010000106         2613 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLZG010000106 DAVLZG010000000
VERSION     DAVLZG010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.106"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            283..657
                     /locus_tag="VYO72_001986"
     CDS             283..657
                     /locus_tag="VYO72_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1708290.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            865..1767
                     /locus_tag="VYO72_001987"
     CDS             865..1767
                     /locus_tag="VYO72_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708291.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            1823..2155
                     /locus_tag="VYO72_001988"
     CDS             1823..2155
                     /locus_tag="VYO72_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1708292.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            2152..>2613
                     /locus_tag="VYO72_001989"
     CDS             2152..>2613
                     /locus_tag="VYO72_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708293.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDN"
BASE COUNT          859 a          333 c          482 g          939 t
ORIGIN      
        1 atacttttat ttatattagg tgtattgcta attggaattg cgttactaag tcaaaaaaaa
       61 taaattttga aatagtatta gtgagttcgc aatcatttat tgctagtggt ttagaactgt
      121 taagtttcaa acaataattg attttaaacc ttaggtaacc tataaaaaca aataaggtag
      181 agaaaggata tcttatctag gtagctaagt gataaaaaca cagtcgtcta tcacttgtta
      241 ggaaacgatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
      301 aataattatg ttgctcttga gcaagaagag atgatgtatc ttgatggggg attttctatt
      361 ctgagatggc ctgttgcaac agccattaat atagctttta atggtgtttt aggtggagga
      421 gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca
      481 attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt ggcaggattt
      541 gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcgatgc tattacaaca
      601 atctgggcca acaatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta
      661 gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata
      721 tcatccataa tttttttagc ctatgatttt gttagcgaag aaataaaaaa gttgattatt
      781 tggatgaatg tcgttttttt gattttaatc atagcaatga taatttatcc aaaattaaga
      841 aaatgataag gacactgtaa aattatgata cgtaaactaa tcattttttt attaatgctc
      901 cctctttttg tcttgtggct agagttgcat ttgttagtga gtaacttgca attgaatcta
      961 gaaattcccc ttgattttgt ggttagtacg agtcttgctt tctgtagttt gattttatca
     1021 aaaatagttt tagacatact atacgcattg aaagatttgt acaagaaaga agctcttatt
     1081 acgatttttc cttttatttt tataggcagg aagaaagtaa atgtgaggtt ctcgccctat
     1141 ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt
     1201 tttattcttg aaattgctat tattctagta tttattttaa aaattccttt tgcaatcatc
     1261 atgcttacta caatattttt ctggactata atggatatca atcatctcgt ttttaataag
     1321 acggaatttc tttttaatca aaataaatgg gaaaaagaag attcgtttga aagcgatttg
     1381 acgaaaacgt taaaggataa gatacaaaaa tcagagctaa gttattctga cttaatgtct
     1441 cttcagctgt atgatgcgat gaaccaatcc acctttttaa cggatagtga actttttgag
     1501 gatattttga aaaaaatcga agattctcat aacacccttc tgtgtacagg tcttgtcgag
     1561 ttactgctgt atgaaatgtc tattagtaac aataacaact ggtccaacaa ggttgataaa
     1621 attaggatac acctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta
     1681 aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta
     1741 ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt
     1801 tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga
     1861 tgaagaagaa atgatgtatc ttgatggggg agcttattta agcaagcgtg cttgtcaagg
     1921 aatttgcgta gctttagcta tgagttcagg aacttttata gcattagctg gagctgcagt
     1981 tttaaccaaa aaactaataa actatattaa ggttggaggt cttggaggct ggcttattgg
     2041 tgcagcagca ggaaaaatag cttactgtat tggatatggt gctcttaata gaggttgtga
     2101 tattagcggg aacccttatc cttgggatgg atttatatct gcgacagtaa gatgaataat
     2161 gtagataaga ttcgaaaaat acatattatc gtatgttggg tgtatatatt tttatcattc
     2221 agggcgatta taaatgacac ggagtatttt ttgcttattt ttttagcttt tatctactca
     2281 atagtatcac tacctctata ttctgtgaaa aataaaatag tatctatctg tctagccata
     2341 aattcgattc tgttaatgag tttccccatt ttaatcaata agtttttccc agaaagtttt
     2401 ttgacttata ccgtattaat aagtgttttt atcctagagt tagcaatctt tcatttaatt
     2461 ggggaagatt ttgctactaa attgactaac gaatataaga aaattagtca gtttagaagc
     2521 aaggtgtctc aatcttcttg gataaaatat ttagagattt ctagttttat attaactata
     2581 tttccatcta ttctttacgg tacagttgat aat
//
LOCUS       DAVLZG010000107         2459 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLZG010000107 DAVLZG010000000
VERSION     DAVLZG010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.107"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            109..273
                     /locus_tag="VYO72_001990"
     CDS             109..273
                     /locus_tag="VYO72_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1708294.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            357..923
                     /gene="amaP"
                     /locus_tag="VYO72_001991"
     CDS             357..923
                     /gene="amaP"
                     /locus_tag="VYO72_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1708295.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            935..1105
                     /locus_tag="VYO72_001992"
     CDS             935..1105
                     /locus_tag="VYO72_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1708296.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1136..1744
                     /locus_tag="VYO72_001993"
     CDS             1136..1744
                     /locus_tag="VYO72_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1708297.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1775..1978
                     /locus_tag="VYO72_001994"
     CDS             1775..1978
                     /locus_tag="VYO72_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1708298.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2088..2360)
                     /locus_tag="VYO72_001995"
                     /pseudo
     CDS             complement(2088..2360)
                     /locus_tag="VYO72_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          848 a          372 c          478 g          761 t
ORIGIN      
        1 gattttttga tattaaaata aaaaaggagg gtaggcagtg ttgtgatcaa ttattgctgg
       61 aggtcttatt ggtctcttgg caggtaaaat cactaaaaaa gtagttctat gggaatcatc
      121 gcaaatgtat tcgctggttt agtcggggca tatgcaggac aatctctttt aggtagttgg
      181 ggtccatcaa tcgctggaat ggctttgctc ccatctattg taggtgcagc gattgtgatt
      241 actgtagtgt cattctttac aggtagaaag taaacttttc gccagtaaag ttagcaaact
      301 atttttaaat caatgacggg aaaaatagtt taaatgttaa atcgaaagga ttgtatatgt
      361 caaaagcaaa gaaaatatgt ttcattattt tctgtatttt aatcttgaca attttccttc
      421 ctgttttgat agattatcat caagttagtg atctaggtat tcatctactt agctggagac
      481 agaactccgt agttgaattc tatcttgcta gatatgtctt ttgggggaca gtggttctat
      541 caactttagt tttattatcc attttagttg tgatgtttta tcctaaacgt tacttggaaa
      601 tccaacttga aactaaaaac gatacattaa aattaaagaa ttcggcaatc gaaggttttg
      661 ttagaagttt ggtgagtgat catagattga tcaagaaccc aactgttcat gtaaatttac
      721 gaaaaaataa atgtttcgtt catgtagaag gtaaaattct tccttcagac aacatcgctg
      781 acagatgcca aataattcaa aatgaaataa ctaatggatt gaagcagttt tttggtattg
      841 agcgtcaagt aaaacttgaa gttgcagtaa aaaattacca accaaaacct caaaacaaaa
      901 agactgttag tcgtgtgaag taaggaagta aaaaatggaa tggcttaaac aatatcgata
      961 tccaattatc gctggtctca taggcgtatt tctggcttgt ttgattgtct cctttggctt
     1021 cttcaaaaca atatttgtat tgattttagg agcactggga gttgcagctg gattatatat
     1081 cgaaaaaaac tatatagata aataaaaatt actaatttaa ttaaaggagt ttcatatgtc
     1141 aaacgaaaaa aacacaaata ctaacgtaga aaagaaagat gctactgttg tagctcacga
     1201 aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg gtctttcact
     1261 agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc ttaaagaaaa
     1321 aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta aaacacaagt
     1381 tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt tatattcaga
     1441 aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa ttgttgaaat
     1501 caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact cagtaagcct
     1561 tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag aacaattcga
     1621 aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag ttagcgaagg
     1681 tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca ctcgtgtaaa
     1741 ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa aattaaatca
     1801 agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa aaatggaaaa
     1861 agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gttgccgaag acgctaaaga
     1921 cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg agtggcgacg ataaataagg
     1981 ttaaaagtta ctttatcttt ttggtaacat tagtcaaaag agtctgagtc aagatgattc
     2041 tcagaaaaca aaaagctaga gattcccaat tgcggaactc tagcttttta attttgcctc
     2101 tttctcttat tatatttcag caggttgttg gccatgagta tgaatcccat gtcaattctc
     2161 acttgacgct tacctctcag atgacatctc ttataaccca aacaaacctt tatctgccca
     2221 aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt ggaagataaa
     2281 agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata cagtcccttt
     2341 tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct gtttgctttc
     2401 tatctcccct ttttcataat gtatagtaaa atgaaataat aacaggacga atcgatcgg
//
LOCUS       DAVLZG010000108         2385 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLZG010000108 DAVLZG010000000
VERSION     DAVLZG010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.108"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..423
                     /locus_tag="VYO72_001996"
     CDS             <1..423
                     /locus_tag="VYO72_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1708299.1"
                     /translation="NQEQLFDQVATLLEEREIVTPTYREALITREKSFPTGLDMEFLG
                     KDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQ
                     TNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            461..766
                     /locus_tag="VYO72_001997"
     CDS             461..766
                     /locus_tag="VYO72_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1708300.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            814..2289
                     /locus_tag="VYO72_001998"
     CDS             814..2289
                     /locus_tag="VYO72_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1708301.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          706 a          470 c          472 g          737 t
ORIGIN      
        1 aatcaagaac aactctttga tcaggttgca actttattgg aagaacgaga aattgtcact
       61 ccaacttatc gtgaagcctt gatcacgcgt gaaaagtcat ttccaactgg tttagatatg
      121 gaatttctag gaaaggactt gccaaatgta gcgattcctc atacagatat tgttcataat
      181 ctagctgaga aagtggtggt tgttcgatta gaaaaaccag taacttttca caatatgata
      241 gctcctgata aggaagtaga agtatccttg ctcttcttta tcatcaataa ctcaagttca
      301 agtcaaacaa atattctggc tcagttgatg gactttttca caggaaatgg acatcttgaa
      361 gacctatcaa aaatttccga accagaaaaa ctttatgctt acattgctga aacaaccgct
      421 taatcttgtc tattaaaaaa taaaatcgga ggaaatctaa atgattaaaa ttcttgctgc
      481 ctgcggtgca ggtgttaact caagtcacca aattaaaagt gctctagaag aagaactttc
      541 aaaccgtggt tatgatgttc actgtgatgc agtcatggtg aaagatgtaa acgaagacct
      601 tatgaaaggt tacgatatct ttacaccaat cgctgcaaca gaccttggtt ttgaaccagg
      661 tatcccagtt atcgaagctg gaccaatctt attccgtatc ccagcaatga gcgctccagt
      721 atttgacaat attgaagcag ctattaaaga acatggatta agctaattct aatttgttaa
      781 cattcatata acataaaaaa gggaggaact gttatggatg caatctttga cctaatcgga
      841 aaggttttca atcccatctt agaaatgggt ggacctgtca tcatgttgat cattttgaca
      901 gtattggctt tactttttgg agtgaaattc tccaaagcgc ttgaaggtgg tatcaaactt
      961 gccatcgctc ttacaggtat cggtgctatc atcggtatgc taaatggtgc tttctcagca
     1021 tcacttgcaa aattcgttga aaacactggt atccaattga gtattacaga cgttggttgg
     1081 gcaccactcg caacaatcac ttggggttct gcttggacac tatacttctt gctcatcatg
     1141 ttgattgtca acgtagtgat gcttgctatg aagaaaaccg atacacttga tgtcgatatc
     1201 tttgatatct ggcacttgtc tatcacaggt ctcttgatta aatggtatgc tgataacaat
     1261 ggtgtgagtc aaggggtttc actctttatt gctacagcag ctatcgtcct tgtcggtgtg
     1321 ttgaaaatta tcaactctga cttgatgaaa cctacatttg atgaccttct taacgcccca
     1381 agttcatcac caatgacatc aactcacatg aactacatga tgaacccagt tatcatggtt
     1441 ttggataaga tttttgaaaa attcttccca ggccttgata aatatgactt tgatgctgct
     1501 aaattgaaca agaaaatcgg tttctgggga tctaaattct tcatcggttt catccttggt
     1561 atcgttatcg gtattatggg aactccacat ccaattgcag gtgttgcaga tgcagataaa
     1621 tggcgtcttg ttatcaaagg atggttgtct cttggtttga ctgccggtgt atctttggaa
     1681 ctcttctcac ttatcggttc atggttcatc gcagccgtag aaccactatc acaaggtatt
     1741 acaaacgttg ctactaaacg tcttcaagga cgtaaattca atatcggtct tgactggcca
     1801 ttcatcgctg gtcgtgctga aatctgggct tgtgccaacg tacttgcacc aatcatgttg
     1861 attgaagcag tgcttctttc aaaagttgga aatggtatct tgccacttgc aggtatcatc
     1921 gctatgggtg ttactccagc tctcttggtt gtaactcgtg gtaaattgct ccgtatgatt
     1981 atcttcggaa cactcttgtt gccactcttc cttctttcag gtacacttat tgcaccattt
     2041 gcaacagaac ttgctaaagg tgtaggtgcc ttcccagaag gtgtgagcca aactcaattg
     2101 attactcact ctactcttga aggaccaatc gaaaaacttc ttggttggac aattggtaac
     2161 actacaactg gtgatatcaa agcaatcctt ggtgcagtag tcttccttgt attctatatc
     2221 ggtatctttg cttggtacag aaaacaaatg atcaaacgta acgaagagta cgcagcaaaa
     2281 gcaaaataat gcgctcctat aaaatataaa cttaatgaaa atcaaagagc aaactaggaa
     2341 gctagccgca ggttgctcaa aacacagttt tgaggttgta gataa
//
LOCUS       DAVLZG010000109         2140 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLZG010000109 DAVLZG010000000
VERSION     DAVLZG010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.109"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..721
                     /locus_tag="VYO72_001999"
     CDS             <1..721
                     /locus_tag="VYO72_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1708302.1"
                     /translation="KFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGS
                     GKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLT
                     FGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSK
                     PSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVE
                     IGTHRELLELGGIYKQLYSNN"
     gene            745..>2140
                     /locus_tag="VYO72_002000"
     CDS             745..>2140
                     /locus_tag="VYO72_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1708303.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDNNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKIL"
BASE COUNT          809 a          254 c          398 g          679 t
ORIGIN      
        1 aaaatttgat aaaaaaatag aattaaaaga tatttggtat aaatatggat tatttgatga
       61 ttatgttttg aaaggaataa atgttactat taaaaaagga gaaactgttg ctattgttgg
      121 agaatcaggt tcaggtaaga gtacattagc taaaatttta ttaggtttat tagaacctaa
      181 tattggttca atagaagttg atggagtaga aaaagaagaa attggtcaaa cattgtatag
      241 aaagattttt ggagcagtgt tacaaaattc aaccctaagt tatggtacct taagagagaa
      301 tttgacattt ggacactttg tttcagatga agaattaatg acaaatctaa attcaattgg
      361 tcttagcaat gtagttaaat ctttacctct tggattagag acaatcatcg ctgaagaagg
      421 taataacttt tctggagggc agcagcaaat gatactttta gctcgttgtc ttttgtcgaa
      481 accttcggta gttgttttgg acgaagcaac aagtagttta gataatttat ctcaacaaat
      541 tacaacttct tacttaagtg aaatcggtac cactaagatt ttaattgccc atcgactaga
      601 tactatcaag tctgcagata agatcttagt aatgcataat ggtgaaattg tagagattgg
      661 gacccataga gaacttcttg aactaggagg catttataag caattgtatt caaataatta
      721 gtttttgatt aaaagggtaa atttatgaag attatgaaaa aaaaatattg gactttagcg
      781 atattattct tttgtttgtt caataattct gttactgctc aagaaatacc taaaaatctt
      841 gatggcaata taactcacac tcagactagc gaaagttttt ctgaatctga tgaaaaacag
      901 gttgactatt ctaataaaaa tcaagaagaa gtagaccaaa ataaatttcg tattcaaatc
      961 gataagacag aattatttgt aacaacagat aaacatttag aaaaaaactg ttgtaaattg
     1021 gaacttgaac cacaaataaa taacgatatt gttaactctg aaagtaataa tttactaggc
     1081 gaagataatt tagataataa aattaaggaa aatgtttctc atctagataa tagaggagga
     1141 aatatagagc atgacaaaga taacttagaa tcgtcgattg taagaaaata tgaatgggat
     1201 atagataaag ttactggtgg aggcgaaagt tataaattat attctaaaag taattctaaa
     1261 gtttcaattg ctattttaga ttcaggagtc gatttacaaa atactggatt actgaaaaat
     1321 ctttcaaatc actcaaaaaa ctatgtcccc aataaaggat atttaggaaa agaggaggga
     1381 gaggaaggaa taatatcaga tattcaagat agattaggtc atggtacggc tgttgtagct
     1441 caaattgtag gggataacaa tattaatgga gtaaatcctc acgttaatat taacgtctat
     1501 agaatatttg gtaagtcgtc agctagtcca gattggattg taaaagcaat ttttgatgct
     1561 gtagatgatg gcaatgatat tatcaatctt agtactggac aatatttaat gattgatgga
     1621 gaatatgagg acggaacaaa tgattttgaa acatttttga agtataaaaa ggctattgat
     1681 tacgcgaatc aaaaaggagt aattatagta gctgcattag ggaatgactc cctaaatgta
     1741 tcaaatcagt cagatttatt gaaacttatt agttcacgca aaaaagtaag aaaaccagga
     1801 ttagtagttg atgttccaag ttatttctca tctacaattt cggtcggagg catagatcgc
     1861 ttaggtaatt tatcagattt tagcaataaa ggggattctg atgcaatata tgcgcctgca
     1921 ggctcaacat tatctctttc agaattagga cttaataact ttattaatgc agaaaaatat
     1981 aaagaagatt ggattttttc ggcaacacta ggaggatata cgtatcttta tggaaactca
     2041 tttgctgctc ctaaagtttc tggtgcgatt gcaatgatta ttgataaata caaattaaaa
     2101 gatcagccct ataattatat gtttgtaaaa aaaattctgg
//
LOCUS       DAVLZG010000110         2015 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLZG010000110 DAVLZG010000000
VERSION     DAVLZG010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2015
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.110"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            23..235
                     /locus_tag="VYO72_002001"
     CDS             23..235
                     /locus_tag="VYO72_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1708304.1"
                     /translation="MSIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKIEDMYDIKV
                     ADEAYKKWVECGKKATSHEEMMRRYG"
     gene            228..959
                     /locus_tag="VYO72_002002"
     CDS             228..959
                     /locus_tag="VYO72_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1708305.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1070..1153)
                     /locus_tag="VYO72_002003"
     tRNA            complement(1070..1153)
                     /locus_tag="VYO72_002003"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1117..1119),aa:Leu,seq:caa)
     gene            complement(1163..1234)
                     /locus_tag="VYO72_002004"
     tRNA            complement(1163..1234)
                     /locus_tag="VYO72_002004"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1200..1202),aa:Gln,seq:ttg)
     gene            complement(1245..1317)
                     /locus_tag="VYO72_002005"
     tRNA            complement(1245..1317)
                     /locus_tag="VYO72_002005"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1282..1284),aa:His,seq:gtg)
     gene            complement(1332..1402)
                     /locus_tag="VYO72_002006"
     tRNA            complement(1332..1402)
                     /locus_tag="VYO72_002006"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1368..1370),aa:Trp,seq:cca)
     gene            complement(1407..1487)
                     /locus_tag="VYO72_002007"
     tRNA            complement(1407..1487)
                     /locus_tag="VYO72_002007"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1451..1453),aa:Tyr,seq:gta)
     gene            complement(1500..1572)
                     /locus_tag="VYO72_002008"
     tRNA            complement(1500..1572)
                     /locus_tag="VYO72_002008"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1537..1539),aa:Phe,seq:gaa)
     gene            complement(1576..1649)
                     /locus_tag="VYO72_002009"
     tRNA            complement(1576..1649)
                     /locus_tag="VYO72_002009"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1613..1615),aa:Met,seq:cat)
     gene            complement(1660..1749)
                     /locus_tag="VYO72_002010"
     tRNA            complement(1660..1749)
                     /locus_tag="VYO72_002010"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1711..1713),aa:Ser,seq:tga)
     gene            complement(1833..1906)
                     /locus_tag="VYO72_002011"
     tRNA            complement(1833..1906)
                     /locus_tag="VYO72_002011"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1870..1872),aa:Ile,seq:gat)
     gene            complement(1941..2011)
                     /locus_tag="VYO72_002012"
     tRNA            complement(1941..2011)
                     /locus_tag="VYO72_002012"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1977..1979),aa:Gly,seq:tcc)
BASE COUNT          667 a          415 c          389 g          544 t
ORIGIN      
        1 gaataatgtt gttactacac aaatttctat tcaacttagt caagagttaa attctttatt
       61 aaatgctatt gttgaagaaa ataatacaac aaagactgac tttattagac aagctgttat
      121 agagaaaatt gaagatatgt atgatattaa ggtcgctgat gaagcttata aaaaatgggt
      181 tgaatgtggc aaaaaagcta cctcacatga agaaatgatg agacgctatg gctaaattat
      241 acgcaatatc tgatatacat ggatacttgg atgaattcag agacgctctc aataaagtaa
      301 atttaaacga taaagataat cgcctatttt tactaggaga ttatcttgat aatggacttc
      361 aatcttttca agtcatttcc aaaataatcg aacttgagga ggtttatcct aatcaaatta
      421 ttactcttct agggaatcat gaagaatggt tttatgattg gttgatttta gataaaccta
      481 ctgcttcagc atttccagaa acaataaaaa gcttcttctc tccagaggaa ttgaactata
      541 tttttaaatc gaatgctaac aactttgaaa caggtgttag aaatgaaatt aaaaataata
      601 tcaaattcaa cccatttata aactggttta aaaagcgata tagggataaa cgctattatg
      661 aaactgatac ccaaattttt gttcatgcag gcattgatga agaagcagga atgctttgga
      721 aagaactaac gagttcaaag atatttacaa acaaatttcc aattaccact ggtagatttc
      781 ataaagctat tatttcgggc catattgctt cttgggaagt agctaaagat agaagatacc
      841 taggtaagat ttactatgat agtaaaagtc attacttaat tgatggagat gtaacgaata
      901 gcaaaacaat acctgttctt tactatgata caattaccca aaaatatcac tttctataac
      961 ttttaatcat gtgcttttat atgaaattag taattattag taacaattcc aagaaatttc
     1021 ttatgacata acaaaaagac aaggtcctaa aaccttgtct ttaatactat accggcggcc
     1081 ggggtcgaac cggcacgtcc ttgcggacac tggattttga gtccagcgcg tctgccaatt
     1141 ccgccacgcc ggcaaatagt aactggggta gctggattcg aaccaacgca tgagggagtc
     1201 aaagtccctt gccttaccgc ttggctatac cccaatataa aataggcgag tgatggggat
     1261 cgaacccacg catgccagag ccacaatctg gtgtgttaac cacttcacca cacccgccat
     1321 aattctatta acacgggcag taggaattga acccacactg aaggttttgg agaccttagt
     1381 tctaccttta aactatgccc gtaaaatgga aggggaggga ttcgaacccc cgaacccgaa
     1441 ggagcggatt tacagtccgc cgcgtttagc ctcttcgcta cccttccaaa atatataaat
     1501 ggcgcgagac ggaatcgaac cgccgacaca tggagcttca atccattgct ctaccaactg
     1561 agctaccgag ccttattgcg ggagcaggat ttgaacctac gaccttcggg ttatgagccc
     1621 gacgagctac ctagctgctc catcccgcgt taatataaaa ggaggatgtg ggattcgaac
     1681 ccacgcacgc ttttacacgc ctgacggttt tcaagaccgt tcccttcagc cggacttggg
     1741 taatcctcca aaatagtttt atacgggaac aagcccgtgt cctcttagtg aacagataat
     1801 attccaatcc cctagtaatg gactaaacac tatgggcacg agtggactcg aaccaccgac
     1861 ctcacgctta tcaggcgtgc gctctaacca cctgagctac gcgcccaagt caaaaacttg
     1921 gtacaaagaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa cagcttggaa
     1981 ggctgtagtt ttaccactaa actacacccg ctaaa
//
LOCUS       DAVLZG010000111         1985 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLZG010000111 DAVLZG010000000
VERSION     DAVLZG010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.111"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            226..495
                     /gene="blpJ"
                     /locus_tag="VYO72_002013"
     CDS             226..495
                     /gene="blpJ"
                     /locus_tag="VYO72_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1708306.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGSGLTCLGGMVGDKLGLSW"
     gene            564..698
                     /locus_tag="VYO72_002014"
     CDS             564..698
                     /locus_tag="VYO72_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEV1708307.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWEILPKQVLEEQQQEVFN
                     "
     gene            635..793
                     /locus_tag="VYO72_002015"
     CDS             635..793
                     /locus_tag="VYO72_002015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708308.1"
                     /translation="MQLGDFAKAGVGGAAARGLQLGIKTGTWQGAATGAAGGAILGGV
                     AYAATCWW"
     gene            796..915
                     /locus_tag="VYO72_002016"
     CDS             796..915
                     /locus_tag="VYO72_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1708309.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1212..1376
                     /locus_tag="VYO72_002017"
     CDS             1212..1376
                     /locus_tag="VYO72_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708310.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            1373..1777
                     /locus_tag="VYO72_002018"
     CDS             1373..1777
                     /locus_tag="VYO72_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1708311.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          629 a          264 c          403 g          689 t
ORIGIN      
        1 atagtatagt aaaacttttt attgcaagga gaataacgaa attaagatat tttagatact
       61 caagattatt gaaatcttag actaaaaata ggtactgcta cctttaagaa gatagtagac
      121 gtatatactt ttttaagaaa atcaaaaaga tactataaaa aatctatttg tttattgaat
      181 ttaagacttt ggtaacaaat tgaaaataaa aaggaggtat tcatcatgaa tacaaaaatg
      241 ttgtcacagt tagaggttat ggatactgaa atgcttgcga aagttgaagg ggggtatagc
      301 tccactgatt gtcaaaatgc actgattaca ggagtcacta cgggaattat aactggtgga
      361 actggagcag gtttggccac tttaggagta gctggacttg ctggtgcatt tgttggagca
      421 cacattggtg caattgggag tggattaaca tgcttaggag gtatggttgg tgataaattg
      481 ggactaagtt ggtaagactt atagtaaaat tatgaggatt ctattctgat ttattttagt
      541 tttttaaaaa aggagtattt gtcatggata caaaaatgat gtcacaattt tctgttatgg
      601 atactgaaat gcttgcttgc gttgaaggtg gcggatgcaa ttgggagatt ttgccaaagc
      661 aggtgttgga ggagcagcag caagaggtct tcaactaggc attaaaacag gaacatggca
      721 aggtgcagca actggtgctg cgggtggagc tatacttgga ggtgtagcct atgcagcaac
      781 atgttggtgg taattatgga ttttaaaagt tttattattg gtttagtagt tggtatattt
      841 ggtccttata tggataattt aattagaaaa atattttcaa aatttcccaa aaaggataca
      901 gatagtaccc cctaaaaaat aaatttctcc cctgtatttg ctagcttaat ttacagggga
      961 gtttctttaa ttttgtttcg cctgtcaaaa tgatatgtga tagcaggatg aaaagtctac
     1021 aaacaagttg gtatcaatac aatataaaga ggaaagtatg tttttcatgc ttgctttttt
     1081 aatttttaca attcaagagg ttttgatgac catttatgat ttgagtgatc caaggtcaaa
     1141 ataagtgcta tactagcagt gtaaatgttc ttgctcaact aagataaatc gcacatttag
     1201 gaggaaatct tatgaagaaa aaaatactga ttattttcgt tctgtatcta atcatgtcca
     1261 tctttctata tccgcttagg gagagtgctt ggtatcagct attttatacc atagcctatg
     1321 tgattgcagt tatgatctat tttgctatca ataaaaagaa aggagaaaag aaatgaaaac
     1381 ttttcttgct aaaaaacgga acatcttcct tgcgagattg ttcttaggtc agttgccctt
     1441 gcttgtttct acttatctat ttctatctcg tcagttttta aatttttccg tagttttcca
     1501 atttctttta gtagttatta acttggcttc tattttggtt actgtttatc tcactaggga
     1561 aatgaggata agagagtttg aagatgatga tttggttagt cctagaacca atcaacttat
     1621 gttcatcggc ttgacaggtt ttatgtctat tatttgtttg tatagaggta tcacagcagg
     1681 agaatcctac caacaaataa tcgcttatat tggcgctgtt ctctgcttaa tcatcatgct
     1741 tctgctcatg tggggcttga agtattataa aaagtagagc ttaatgaagt ataaaagaaa
     1801 agggtaagtg tttttgcaat acttaccctt ttataataga ttccctgcga aacaaaatat
     1861 ggtatagtat agtagattga aactagaata gtacgcctct atttctaaaa cattgttaga
     1921 aatcgatttg actgtcctga tcgatttatc ctgttcttat ttcattttac tatagttcta
     1981 tgaat
//
LOCUS       DAVLZG010000112         1933 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLZG010000112 DAVLZG010000000
VERSION     DAVLZG010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.112"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            188..955
                     /locus_tag="VYO72_002019"
     CDS             188..955
                     /locus_tag="VYO72_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEV1708312.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            957..1589
                     /locus_tag="VYO72_002020"
     CDS             957..1589
                     /locus_tag="VYO72_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708313.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT          613 a          327 c          385 g          608 t
ORIGIN      
        1 cccgagaagg gtactctcaa aattatttac ctaacacttc agaaaataca tataattcat
       61 tacaagtcag tttagttgga gtattactac tttttataag tatggtaaat attttatggg
      121 ctaaaaaaag taaatgaaaa taaaatttgg agccctctga aaaagtaagt cctacagttc
      181 aactaaaatg agtcaaaaga tgaatcacct tgatgtaggg gagtttgtct tattgctgcc
      241 tgaacacctc cgttcagagg aagaacatta taaatctgtt tttgaagacg acttaaccag
      301 tcgcatatct agtcaagatg aacgacagca aatgactgct acggtaggtt atttagaatc
      361 aggtcaggat cgttttgtgt ataatacgac ccctatttct taccagcagt ttttgaaaga
      421 tccaatcatc attgttataa caccccaatc aactggtcca cagtccattt tgttttggat
      481 agacgcagta cagaactacg ttctctttaa tcaattgtct gatgcccagg agcttatcca
      541 gagacaaggc attgaaaatt gggtctcaga aatgcaaaca ggttaccaca actacatcac
      601 attattggat aatatccaga gggaacgttg ggtaatgcta gcaggagctg tgcttgggat
      661 tgcaacttca atcttgttgt ttaacactat gaataggctc tactttgaag aatttagacg
      721 tgccattttt atcaaacgca ttgcaggtct caggttctta gaaatccatc gcacttatct
      781 ctttgctcaa ctgggtgtgt ttttactggg atttgttgcg agtgtatttc ttcaggtaga
      841 gataggagtt gctttcttag tcttgttact ctttactggt ctatctcttt tacagttaca
      901 tgtccaaatg cagaaagaaa acaagatgtc cattcttgtt ttgaagggag gttaatatga
      961 ttgaacttaa acaggtgagt aaatcttttg gagaacgaga gttattttcg aatctttcaa
     1021 tgacatttga ggctggaaaa gtctatgcct taattggttc aagtggtagc ggaaaaacaa
     1081 ccttgatgaa catgattggg aaattagaac cttatgatgg gacgattttt taccgaggta
     1141 aagacttggc caattataaa tcgagtgatt ttttccgtca cgaattgggc tacctcttcc
     1201 agaactttgg cttaattgaa aaccaaagta ttgaagaaaa ccttaagcta ggtctcattg
     1261 gtcaaaagtt gagtcggtcg gaacagcggt tgaggcagaa gcaggcttta gaacaggtcg
     1321 gcctggctta tcttgaccta gataagcgca tctttgagtt atcgggcgga gaatcgcaac
     1381 gggttgcctt ggcaaaaatt atcttaaaga atccaccctt tattctggca gatgagccaa
     1441 cagcttcaat agacccagca acctctcagt tgattatgga gattttgcta tctcttcgag
     1501 atgataatag gctaatcatt atcgcaacac ataatccggc aatttgggag atggctgatg
     1561 aagtgttcac gatggatcat ctgaaataaa aatccttgtt tttaattgca cgatgagtta
     1621 ctgaaatatt atcatgaatc aagaattgga gttaatttag aattgtactt tattaatatt
     1681 gaggtaactt tttcttgata aaggaagaaa taatggagag gaagttagaa tgaaaaaatt
     1741 cgacaattat attattgaga agccttgcga ttctaattca gataaactgc aaaaaatctt
     1801 aataattgaa agtttggtag atgatatttt gcaattttct ctcagaatca ataatagtgt
     1861 aggagagatt ttcctcctac aaccgtttta aaagaaaact atctttatcc caaatcattc
     1921 atacctctct caa
//
LOCUS       DAVLZG010000113         1873 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLZG010000113 DAVLZG010000000
VERSION     DAVLZG010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.113"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(1..988)
                     /locus_tag="VYO72_002021"
                     /pseudo
     CDS             complement(1..988)
                     /locus_tag="VYO72_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(1001..1750)
                     /locus_tag="VYO72_002022"
     CDS             complement(1001..1750)
                     /locus_tag="VYO72_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1708314.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFQYVSDSSMVGYMGKTKELKMYQEELDEKNYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          647 a          342 c          210 g          674 t
ORIGIN      
        1 tcaatagttc attaattata cttaaaatag ctgactcttt gtaattatct gaattatatt
       61 tcatccccaa tttatatatt cctactatct ttggctttcg ttccaatatt tgtttaacta
      121 tgaactgttt tctatttgtg tttgaaatat caatcgcttc tatcactggg gcatttattt
      181 ctataaattc tttttttaat tgtttagtat ctttgggaag acaatatcct ccaaatccaa
      241 aagaaggatt attataaaaa tttccaattc ttggatctaa acaaacacct tttattacaa
      301 cttcagcatt taaacttctc ctctcagcaa aagaatctag ttcattaaaa aaagcaacac
      361 ggagagctaa gaatgtgtta gaaaaaagct taattgcttc tgcttcagta ggagaaacta
      421 acataacatt tttaatattg gcagtactat gagtactaat cgaaaggaac aactctgcaa
      481 tttttcttcc ttcaactgtc tcatctccaa caactatgcg acttggatat aaattatcat
      541 atatagaaca accttctctc aaaaattcag ggacaaaaat gatatttttt gtatcaaaca
      601 gcctttttaa tttgtttgaa aagccgatcg gaactgttga ctttcaaata atctttccat
      661 taggttttac cctcagaatc ttcgataccg tttgttcgat ttcatatgta ttaaaactac
      721 caattttctc atcataatct gtcggaagcg caataatata ataatcaata ttatttttaa
      781 tttcagaaaa tgtatcaaaa aaagtaatat ttaagttatt ctcgcaaaaa aacttcataa
      841 gctcttcatt tttagatgga agaatgccct tttttaaatt atttattttt acagaatcta
      901 tatcatatgc aacaacttta tatttagatg caaatagtaa cgcgtaggcc agcccaacat
      961 gccccaaacc aattactgct atattcataa aactacttcc ttatttctta atccaaaatc
     1021 taatagaata agctgcccca ttccttaaat acaactcttt aatattgttt aaaagttttt
     1081 caactgattt ccagattatc aaaatctgag atttatagca caatattgat gatattctat
     1141 caatataatt tttttcatca agttcctctt gatacatttt taattcttta gtttttccca
     1201 tataaccaac catactacta tcacttacat attggaagtc ctcataatat attactttat
     1261 aacgcataaa ttcaagcgcc cttccaatac tattcacaaa aacatgatca acatggtcac
     1321 caagtgaaag cggacaatat acgacacatt tgtcgtctaa atgcattaac agctctttta
     1381 tgatatcatt ctttaatgtg tcctcatttt ttaattcact atagatatga cggtatagaa
     1441 aattgccatt tctatctttc ctatagagac attcatagta cgataagtgt ctaaaatcac
     1501 attgtagacg ttcacaagct aacctgtctt ctttcttcct ttcttcaatc ggatatttcc
     1561 caaggttaca caacttatga aattgcttag cagagggctg tagctgttgg ctcaaagggt
     1621 aaccagaaaa tatagtaata acaagtacaa tttctccttc tgaagttaat tttgaaatat
     1681 aatcaccaca ggaaaaaatt gcgtcatcta aatgtggaga taaaaagata tacttagtat
     1741 tgttactcat aaccattccc tctacaattt atctaaaaac tcacttagtg tctgattaaa
     1801 ttccacatca tcaaaaaaat tcaccttatt cttaataatg aatatttcgt taaataaaca
     1861 tatatataaa tat
//
LOCUS       DAVLZG010000114         1798 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLZG010000114 DAVLZG010000000
VERSION     DAVLZG010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.114"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            20..1636
                     /locus_tag="VYO72_002023"
     CDS             20..1636
                     /locus_tag="VYO72_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708315.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          635 a          211 c          331 g          621 t
ORIGIN      
        1 tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa aatttagttt
       61 attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa ctattaatgc
      121 tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat tgtcaatcta
      181 ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa attatcaggt
      241 tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag acatctctaa
      301 ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt ggctaaataa
      361 tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa taaaaggaat
      421 ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat tgactgtagc
      481 caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat cgaaaatgcg
      541 agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta gtgagactat
      601 attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc ctaagaaaat
      661 taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg tagaaacgtt
      721 agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg tttttttaac
      781 aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa taggagcact
      841 aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct ctattattgg
      901 tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa ataaaatgaa
      961 tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa aaaatatttg
     1021 ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc aacgtaatga
     1081 aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa aattattgaa
     1141 tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata taaaaaaaac
     1201 ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt atttgtttga
     1261 aggtacgatt agagataata ttttattgga agaaaattat actgatgaag aaatactaca
     1321 gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt tagattatta
     1381 tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta ctttagctag
     1441 agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg ctatcgatag
     1501 gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga ctgtcattat
     1561 tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat atcaatttcc
     1621 aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt gaagcttatg
     1681 aggtaattac tgaagagaaa aaagtatcat ttttttatgt agatgagaaa cccttaaggt
     1741 atctgttatt tgactatata tttctactag ttctagctaa aaaaaaatat cccaatct
//
LOCUS       DAVLZG010000115         1689 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLZG010000115 DAVLZG010000000
VERSION     DAVLZG010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1689
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.115"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..>1689
                     /locus_tag="VYO72_002024"
     CDS             <1..>1689
                     /locus_tag="VYO72_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1708316.1"
                     /translation="EFSGLDFSLWQDYIQSTGSIKELWPSQIELGKQGIFSGKSGIVQ
                     MPTSSGKTASINLTLRSAFYSNRIDNALIVAPFRALCREIYRDINAHFVDENNVIVSE
                     VFDLPEIPQDFSIFNDGKKRVFILTPEKLLFLLRNHQSFIDEIGLCIFDEAHLFDDPS
                     RGTNFELLLSTVKQIFPKGIQKILISAVIPNSEAINRWFNEDGVIVSNNSIKTTEKRV
                     AFSDLNGSNEQLYFIDPITFEEEFFVPRTVSVSELEQLGKERKQKVFPELTNANDISI
                     YYGTKLINNGGVGIFCGRKDTVNVILRRFIDLNNRNYDLTDFLKNSDRSEVEKIGNLI
                     GQNLGYDSVEYTCSQLGVFSHHSGIPMGIRIAIEYAFSKSKINNVVCTSTLAQGINLP
                     IKYLIISSVYQAGDAIKVRDFQNLIGRAGRAGKYTEGTIILTEPNIYKSPKNKWKKQN
                     YKALLNPINTEGCQSNILSIIQFKSVVPTDYRFAPIKFDFWNLIKERFDSSVDYRTKI
                     NNILSKLKRKNSLYFKDFNSKIDQIDNTLIAIENYIASMYATELETDSLAENTF"
BASE COUNT          627 a          202 c          304 g          556 t
ORIGIN      
        1 ctgaattttc aggattagat ttttctttat ggcaggatta tatacaatca acaggaagca
       61 taaaggagct ttggccatct caaatcgaat tagggaagca aggaattttt tcaggtaaat
      121 ctggaatcgt tcagatgcca acaagttcgg gtaaaacagc ctcaatcaat ctaactttaa
      181 gatcagcatt ttattcaaat agaattgata atgcattgat tgttgcacct tttagagcat
      241 tatgtagaga aatatatcga gatattaatg cacatttcgt tgatgagaat aatgtgattg
      301 ttagtgaagt ttttgattta ccggagattc cacaggattt ctcaattttt aatgatggta
      361 aaaaaagagt ttttatactt actccagaga aattgttgtt tttattgaga aatcatcaaa
      421 gttttattga tgaaatagga ctttgtatat ttgatgaagc acatcttttt gatgatccaa
      481 gtcgtggaac caattttgaa ttactgttgt caacggttaa acaaattttc ccaaaaggaa
      541 tacagaagat tttaatatct gctgtaatac caaatagtga agctataaat cggtggttta
      601 acgaagatgg agtaattgtt tctaataatt cgattaaaac aacagagaaa agagttgcgt
      661 ttagtgattt aaacgggagt aatgagcaat tatatttcat agatcctatt acatttgaag
      721 aagaattttt tgttccacgt actgttagtg ttagtgaatt agagcagctt ggaaaagaac
      781 gcaaacaaaa agtttttcca gaactgacaa acgcaaatga tataagtatt tattatggga
      841 ctaagctaat taataatggt ggagtaggaa ttttttgtgg aagaaaagac acggtcaatg
      901 ttattttacg aagatttata gacttaaata atagaaatta tgatctaact gatttcttaa
      961 aaaactcaga taggtctgaa gttgaaaaaa taggaaattt aattggtcaa aatttaggat
     1021 atgatagtgt tgaatataca tgtagtcagc taggagtttt ttcacatcat tcaggtatac
     1081 ctatggggat acgcattgct atagagtatg ctttttcaaa aagtaaaata aataatgtag
     1141 tatgtacttc aaccttagca caaggtataa acttacctat taaatacttg attatctcaa
     1201 gtgtgtatca agcaggagat gcaataaaag ttcgtgattt tcagaatttg ataggtagag
     1261 caggaagggc tggaaaatat acagaaggaa caataatttt aacagagccc aatatttata
     1321 aatcaccaaa aaataagtgg aaaaaacaaa actataaagc attgttaaat cctattaata
     1381 cagagggttg tcaaagtaat attctcagta ttatacagtt taaatcagta gttccaactg
     1441 attatcgatt cgctcctata aaatttgatt tttggaattt gattaaagag agatttgaca
     1501 gttctgtaga ctacagaaca aaaataaata atattttatc aaaattaaaa agaaagaaca
     1561 gtctttattt taaggatttt aattctaaga tagaccagat tgataatacc ctaattgcaa
     1621 ttgaaaatta tattgcttct atgtatgcta ctgaattgga gactgatagt ttagctgaaa
     1681 atacatttg
//
LOCUS       DAVLZG010000116         1678 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLZG010000116 DAVLZG010000000
VERSION     DAVLZG010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.116"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            77..484
                     /locus_tag="VYO72_002025"
     CDS             77..484
                     /locus_tag="VYO72_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1708317.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQTDEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            649..948
                     /locus_tag="VYO72_002026"
     CDS             649..948
                     /locus_tag="VYO72_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1708318.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="VYO72_002027"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="VYO72_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1708319.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDDQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          566 a          330 c          299 g          483 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactctc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca aactgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcaac tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactaag cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaggt
     1201 attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtagcaaga
     1261 tagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
     1381 tttactggga tgatcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacacc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt
     1621 ttcattttac tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtct
//
LOCUS       DAVLZG010000117         1673 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLZG010000117 DAVLZG010000000
VERSION     DAVLZG010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.117"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            335..>1673
                     /locus_tag="VYO72_002028"
     CDS             join(335..776,776..>1673)
                     /locus_tag="VYO72_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1708320.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRT"
BASE COUNT          577 a          264 c          373 g          459 t
ORIGIN      
        1 tgcggtaact ggagtgcttt tagttgggaa aattgttaat tcatttaaat tgtaaacttt
       61 agggattctc tgaagttatg gatgtcgttc caatatgtgc acgttggaat gttagtgctt
      121 atatgggggg aacagaatcc tctcttgatt gaagacaagt tagccattag gctggtttgt
      181 ctctttgtca actgtagtgg gttgatataa tagtattagt gagtgggata aaagtttcat
      241 ttagtttatt cagtacaaat ttaacgggtc aagatttatt gaactgcacc ccaatagtta
      301 gacagaaaaa atctaacttt tggggtgttt tattatgaaa ttgagttatg aagataaagt
      361 tcagatctat gaactaagaa agcaaggaca aagcttcaaa cagctttcaa aaagatttgg
      421 tgtggatgtt tctggtctaa agtacatggt gaaattaatt gaccgttatg gcatagaaat
      481 cgttaaaaaa gggaagaatc gtcactattc ttctaaattg aaacaagaaa tgatggataa
      541 agccttactg gaaggttgtt cacaaagaag tattagtctt gattatgccc tcccaaacca
      601 aggaatgctt tcattttggc cggcacaata caagaaaaac gggtatacta ttgttgagaa
      661 aacaagaggg agaccagcta aaatgggacg taaacggaag aagacttggg aagaaatgac
      721 agaactagaa cgactccagg aggagaatga acgcttacgg actgaggtgg cctacctaaa
      781 aaagttaaaa gagttagagg aaagggacga agccctagag cgagaaaggc agagacagtt
      841 agagaaatgg tttcaggagg atttcgacta gattttcttc ttgaaacagc acgtttagct
      901 cgctcgactt actattatca gttgaaacaa ctggatgggg ttgataaaga taaagagatt
      961 aaaaccgaaa ttcagggcat tgataatgaa cataaaggca actatggcta tcgtcgaatc
     1021 catttagaac taaggaatcg tggttttgtg gtcaatcata agaaagttca acggttgatg
     1081 agaattcttg gtttaacggc tcgaattcgc cgtaaacgga agtattcttc ctaccaagga
     1141 gagattggca agaaagcaga gaatctcatt caacgccagt tcgaagcatc gaggccaatg
     1201 gaaaagtgct atacagatgt gacagagttt gccattccaa atagcacaca gaaactctat
     1261 ttatcaccag ttttagatgg ttttaacagt gaaatcattg cttatcatct ttctacttcg
     1321 ccaaacttag aacaagtgaa gagtatgtta gaacaggcct ttacagagaa atactatgag
     1381 aatacgattc tccatagtga ccaaggctgg caataccaac acgattctta tcatcggttc
     1441 ctagagagta aggaaattca agcatccatg tcacgcaagg gcaacagccc agacaacggc
     1501 atgatggaat ctttctttgg cattttaaaa tccgaaatgt tttatggcta tgagaagaac
     1561 tttagatctt tagaaaacct tgaacaagct attgtggact acattgatta ctacaacaac
     1621 aaacgaatta aggtaaaact aaaaggactt agttctgtgc agtacagaac taa
//
LOCUS       DAVLZG010000118         1617 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLZG010000118 DAVLZG010000000
VERSION     DAVLZG010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.118"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            51..122
                     /locus_tag="VYO72_002029"
     tRNA            51..122
                     /locus_tag="VYO72_002029"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:83..85,aa:Gln,seq:ttg)
     gene            284..1486
                     /gene="rpsA"
                     /locus_tag="VYO72_002030"
     CDS             284..1486
                     /gene="rpsA"
                     /locus_tag="VYO72_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1708321.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT          488 a          269 c          384 g          476 t
ORIGIN      
        1 ccgctccttc gggttcgggg gttcgaatcc ctctctctcc atttcattaa tggggtatag
       61 ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc cagctacccc
      121 agttcttagg taataatcaa gataaaaagc aaaatatctt agggtatttt atttttataa
      181 ttgaaagacg tgaatgatat gaacatgtcc ttgcgggtgc ttaggaaaaa aattataagt
      241 atgtcaagtt taagaaaaac ttgattgttg gaggattttt tagatgaatg aatttgaaga
      301 tttgctaaat agcgttagtc aagttgagac tggtgatgtt gttagtgctg aagtattgac
      361 agttgatgcg actcaagcta acgttgcaat ctctggaact ggtgttgaag gtgtcttgac
      421 tcttcgcgaa ttgacaaacg atcgtgatgc agatatcaat gactttgtta aagtaggaga
      481 agtattggat gttcttgtac ttcgtcaagt agttggtaaa gatactgata cagttacata
      541 ccttgtatct aaaaaacgcc ttgaagctcg caaagcatgg gacaaacttg ttggtcgcga
      601 agaagaagtt gttactgtta aaggaacgcg tgccgttaaa ggtggacttt cagtagaatt
      661 tgaaggtgtt cgtggattta tcccagcttc aatgttggat actcgtttcg tacgtaatgc
      721 tgagcgtttt gtaggtcaag aatttgatac taaaatcaaa gaagttaacg ctaaagaaaa
      781 ccgcttcatc ctttcacgtc gtgaagttgt tgaagcagct actgcagcag ctcgcgctga
      841 agtattcggt aaattggctg ttggtgatgt tgtaactggt aaagttgctc gtatcacaag
      901 cttcggcgct ttcgtcgacc ttggtggtgt tgacggattg gttcacttga ctgaattgtc
      961 acatgaacgt aacgtatcac caaaatcagt tgtaactgtt ggtgaagaaa ttgaagtgaa
     1021 aatccttgat cttaacgaag aagaaggacg tgtatcactt tcacttaaag caacagtacc
     1081 aggaccatgg gatggcgttg agcaaaaatt ggctaaaggt gatgtagtag aaggaacagt
     1141 taaacgtttg actgacttcg gtgcatttgt tgaagtattg ccaggtatcg atggacttgt
     1201 tcacgtatca caaatttcac acaaacggat tgaaaatcca aaagaagctc ttaaagttgg
     1261 tcaagaagtt caagttaaag ttcttgaagt taacgcagat gcagaacgcg tgtcactttc
     1321 tattaaagct cttgaagaac gtccagccca agaagaagga caaaaagaag aaaaacgtgc
     1381 tgctcgtcca cgtcgtccaa gacgtcaaga aaagcgtgat ttcgaacttc cagaaacaca
     1441 aacaggattt tcaatggctg atttgtttgg tgacatcgaa ctttaatcaa attgaaaatt
     1501 cacaaaatcc tttgtttact aaacaaggga tttttctggc tctttgtcaa ctgtagtggg
     1561 ttgaagaaaa gctaagctcg agaaaggggc tctttgtcaa ctgtagtggg ttgaagt
//
LOCUS       DAVLZG010000119         1570 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLZG010000119 DAVLZG010000000
VERSION     DAVLZG010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.119"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..724)
                     /locus_tag="VYO72_002031"
     CDS             complement(<1..724)
                     /locus_tag="VYO72_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708322.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYK"
     gene            complement(881..1126)
                     /locus_tag="VYO72_002032"
     CDS             complement(881..1126)
                     /locus_tag="VYO72_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708323.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
BASE COUNT          601 a          274 c          192 g          503 t
ORIGIN      
        1 ctttataaaa aatatctaag tcaacctcac tctgattctg aagcaagtag gagtcaagca
       61 aattttcaaa aatagctaac aatatgattg gtgtaaagtt tttgtattca catgtcaagt
      121 attctgagta tcgtgcagat gatatttctt ttatataact ttttgaaagc aagatttttt
      181 caaattcatc atctattatt aatcttctat ttccaatcca agcggtatta ccacccaaat
      241 aagattgtac aaatagcaat atataagaaa acatgaacgt aaatactgaa aaaggtagaa
      301 ttctatgcgt aaaaaaatag acgataatgg tagccaggag taaagatatc tctcgtgaca
      361 atcgaattct tttcagcatc ttttttaaca gtccgtaagg ttgtccttgg caatattctt
      421 gaactaaatt aatcggaatg acatctctca ccatttctgg aaagtagagt aagtttatag
      481 gttgaaatct ccagctccca tcataagtaa atggatatag aaccaaatac ttaaaagatt
      541 tttttcttat aaacttaatt atcacaatat gaatgactgt tgcaatgaag tatattaaat
      601 ataaaagtaa aaccgccatc aatatactta caaaaatccc cttggaatca atcaatggaa
      661 aataaaatat tgcaactaga agcgaataaa gtcccgctaa taaatatttc tgatcatctt
      721 tcattcaaaa caccatatta tttactaaga atgcatcaat acaatagagc aactctgtaa
      781 gtcaatattt gataaagcaa agctttaaac ccttccccag acgttagctt ttattcaacc
      841 cactacagtt gacaaggagc ccaaattatt gataaaaact ttagtcatca tcgtctctat
      901 aaaaatattt tctatacact cttgataata ccaaaattaa tgccaatatc ataccaagag
      961 ctataataat agaatttatt agatttattt tagtatatcc aatcactagt ccaataattg
     1021 gactagcaga catgcttaga tataataaaa ataacaaaaa atgaatttca ccaattcctg
     1081 caaaaaaatg tttcatagct atagttttac gcccataaat acccatcaaa tttaccgtct
     1141 acgatatcta aaccatatgc aatggctcct cctaatgaga agacttcagc aacagtagcc
     1201 gcaatattaa gagcattagt aatagttgcc atactaactc caccaatata tcttgttata
     1261 gcacttagtt acctagataa gatatccttt agcttgcttc caaaatttaa gtctacacct
     1321 ataatatgag ttcatattag tactgctaaa tcctatctat agtaatgtca aacacctaaa
     1381 taaagtcatc tctccaattc attcaagaaa tgaagaaagg caaaaaatct ttaaaataag
     1441 aaaaatgcat attatcaggt gttcaaaaat attgatgata tacgttatat agatagaaag
     1501 atttactcaa tctcattttc aaattgagtt ttttcccagc ctcattttta atttatatct
     1561 tcaatagaat
//
LOCUS       DAVLZG010000120         1439 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLZG010000120 DAVLZG010000000
VERSION     DAVLZG010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.120"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(291..1400)
                     /locus_tag="VYO72_002033"
     CDS             complement(291..1400)
                     /locus_tag="VYO72_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1708324.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT          539 a          261 c          213 g          426 t
ORIGIN      
        1 aataggacga atagatcagg acagtcaaat cgatttctaa caatgtttta gaattagagg
       61 tgtactattc tagtttcaat atactataaa taggtttcat tcgaacttta atagactatg
      121 aaaaccagtg gaacttaccc tgacacggaa ttccactggt tttttcgatt tttatcagat
      181 taacttctac tattcttagc tgtgaaaatt agtttaagac tttaacttat tttcagtctt
      241 ctaatctaaa ggccacttcc agtaaagaaa aatcagggtt ctcctgactt ttacttagct
      301 aattctcttt ctcgttcttt cattatttta tgattttcat acaaacggga taagaactta
      361 gaaatttctt tcaagataga ataggttggc actgcgacaa tcattccaac tacaccatag
      421 atattgcttg acaacaaaag taaaactaaa atcgtgattg gatgaacctt cataacactt
      481 cctacaattc gaggatataa gatattgcca tctacctgct gaacaacaag catataaatc
      541 actgcaatca gcagtctatg gggatcagtg aatatatttg cgatgatcat aggaatcaaa
      601 ccaatacttg gccccacata aggaattaaa ttggctacac cagaaaaaat ggcaaaaact
      661 aaagcatatt ttaaaccaat aatactatag ccaatataag ccaaacaacc tataatgatt
      721 gcgtcaatcg aaactccact aatatagcga gcaatcgtcg catttaaatt ctttaataag
      781 cctgcaatat gcaagcgatc cctctttaga atcgttcttt caagcatggg caagaattta
      841 tgtccatcta ataagaaata aaccaaaaaa actggagtca taatcaaaat caaaacagta
      901 ctgataagag ctgacaagac gctccccaca ctatttgata cgctatttag gatattttga
      961 agaatatcaa cataggataa gtttaactgc tgaattgtag cttctacatc caaattctgg
     1021 agcgcaggat aattagataa gtctatgatt aagtcttgta ctcgactata aatagtttga
     1081 ctagatataa tcaaactaga taactgatta atcaaaatag gtaagagata gacaacacct
     1141 atgaccattc cccagaccaa agtacacaag gtaattaaaa taccaagcaa acgattgagt
     1201 ttacagactt tatttaagaa agtaacaata gggtttgtca aataataaag aaagccccct
     1261 aataaaaatg gaatcataat tgtattaagc acgctaacaa aagggttaat caaagacccc
     1321 atctgtctcc ataggtaaaa gatgatggtt aagagtaaaa tttctgtggt ccaaaaaaat
     1381 aatttatttc tacgaaacat gagttacctc cctcacttta ttttaccata ttttcaaaa
//
LOCUS       DAVLZG010000121         1382 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLZG010000121 DAVLZG010000000
VERSION     DAVLZG010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1382
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.121"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            149..1159
                     /locus_tag="VYO72_002034"
     CDS             149..1159
                     /locus_tag="VYO72_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEV1708325.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
BASE COUNT          500 a          166 c          240 g          476 t
ORIGIN      
        1 aaagcaactt gatatcattg aaatttattt tccaagcttt gatcagcgaa aaaaaggata
       61 taaattaaac ttatctaata gaaaaaaact cccaaatgaa agtttagtta ctattctgca
      121 taatgaagta gaaaatattg cagactcttt ggttattaat aatatttatg acgaatatcc
      181 aatttggagt atacctgtta attttaaagg ttctaaatgg tgtcttgaac aaacgggtaa
      241 tgatatgtat aggggtagag ctggaatatt actgtttatg tactatgtaa aattattgaa
      301 agataaatca tcatatactc aactgtacaa taaaatgtta tctgcaattc cgccatctgt
      361 ttctttatct aagaccacat ttggtttaac tggggatata ggatatttca ttgttctatc
      421 cattatagag gattacgata caaatactct cgcatgctta aattatataa agagtgtttt
      481 aactgagctt gaaaagactg attttgcaag tgtttcaaac aagtctgact atattaatgg
      541 tcttctacct ttaattaata cactggtaag atattatagg agaggaatag agaaggaacg
      601 tgttctaagg ctagtattaa gtttaggtga tacgctatat aatgatgtaa gcgagagaga
      661 taatagtaat tttggatata gttttggcca tggactatca ggtgtaattt ttacattaaa
      721 aaatatttat aaagtgacaa gacttaaaaa atataaagaa ttaattttac aactagttcc
      781 tagggagaaa atcaaaattc attctttgaa gtggtgtagt ggagaatttg ggacattagt
      841 taatcatccc caaagtgttc cagagggaat tgtagctagt ttagataatg atacattttg
      901 ccatggaagt atggccataa taaattttta catcgactac atgaaagaaa tggatactag
      961 tatggaattg gagtctttat tgtgtagtgt tgtaatgaat aaatcaaaag aaggagagta
     1021 tcgtatcgtc caaacaagca atttcccaga tttttctttg tatacaggtg tgactggtat
     1081 tgcttatact tttttaaggt atatcgcact gaatcagaat gacaaaaaga tagttatccc
     1141 ctcattactt gaaatctagc ttaatttata gttttgtttc taaaatagag gtgtccactc
     1201 attaagcaat ataaaaatac caagattgac tagtttaata tgtaattcta taaaatattt
     1261 ttaatagtgt agcttttcgt tgagataata atataataaa gaaaggttct attctaattg
     1321 ctaaacggct tgaggtatat gctactgtta tagaaatgat tttaaactaa aatcaaaatt
     1381 ac
//
LOCUS       DAVLZG010000122         1347 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLZG010000122 DAVLZG010000000
VERSION     DAVLZG010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.122"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            48..1226
                     /locus_tag="VYO72_002035"
     CDS             48..1226
                     /locus_tag="VYO72_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1708326.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALFYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          495 a          242 c          200 g          410 t
ORIGIN      
        1 aaaaatcata ggattttaag aatctgacaa ctaggaagaa aactaatatg accttatcta
       61 agaaacaatt acaactaaga gctaaaatac tggaaacagt ttacacatta ggtcccattt
      121 cacgaattga aatcgctact aaaacaggaa taacacctgc aacaactagc agtatcacaa
      181 atgatctgat taaagaaaat attctcttag aacttggtga agacgaacac gatacaagcg
      241 tagggagaaa aaaaatcctg ctagacattc aagctaaacg attttactac attggttgtg
      301 aactatctga aaaacatttc acttttgctt taggagataa tctaggaaat atcttaaagg
      361 aagagaaaga aattgttact aaacagttaa tccaagaaaa gggaaatcaa ctcattaacc
      421 agacactaaa gcaattctta aataactgct ctgattatga aatagaagca attggaatcg
      481 cgctacctgg tcgctattta gatgattata aaataacaac aaacaatcct ttatggcaac
      541 atatcgactt agaaatgatt caatcccact ttgataagcc tttgtttttc tctaacaatg
      601 ttaactgtat ggctataggt aaacgcctat ttagtcgcca acagaatgac cctaattttg
      661 cttattttca ttttgctaga ggtatgcact gttcttatat ctacgacgga aacatttatg
      721 ggaaaggaaa tctaatgatt ggagaaatag ggcatacagt tgtttcatct gagggagaag
      781 aatgtagctg cgggcgcaag ggatgcttac aaacttttgc tggagaatct tggttaatca
      841 aaaaatcaaa aattctatat catcaatctc cctattctct acttcctagt ttagtcaaaa
      901 atgccgatga tattgatatc caagttattt taaccgctta tcaattaggt gacactggaa
      961 taatcacact tatccatcaa gccttattct atcttagtca aaccatttta aatatcagta
     1021 tgatgattga ctctcaaaaa atctacctac atagtccttt actaacaaat caacacatca
     1081 tccaaaaact atatagtgaa atgaactaca aacccaaact gctctataat cgcctacctg
     1141 aagtcattat tgaaccttac aatgatttta cagccgcaca ctcagctatt gcactttgtt
     1201 tgtatcatac aattctacat tcttaatttt ctattacatt taataaatag gctaaaaaga
     1261 gggagtatat cataaaaagc gaataaacct gttttctgaa aatcagaatt ctgttttgtt
     1321 cgctttcttt atatttggaa ttatact
//
LOCUS       DAVLZG010000123         1331 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLZG010000123 DAVLZG010000000
VERSION     DAVLZG010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.123"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            1..619
                     /locus_tag="VYO72_002036"
                     /pseudo
     CDS             1..619
                     /locus_tag="VYO72_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            769..1023
                     /gene="blpM"
                     /locus_tag="VYO72_002037"
     CDS             769..1023
                     /gene="blpM"
                     /locus_tag="VYO72_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1708327.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            1039..1242
                     /gene="blpN"
                     /locus_tag="VYO72_002038"
     CDS             1039..1242
                     /gene="blpN"
                     /locus_tag="VYO72_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1708328.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
BASE COUNT          438 a          199 c          308 g          386 t
ORIGIN      
        1 cgagaatacc gcacttatga agaaattgcg gctgattttg gtgttcacga aagcaactta
       61 ctccgtcgga gccaatgggt tgaagtaact cttgttcaaa gtggtgttac gatttcaaga
      121 actcctctca gttctgagga cacggtaatg attgatgcga cggaagtaaa aatcaatcgc
      181 cctaaaaaaa gaattagcga attattctgg taaaaagaaa tttcacgcta tgaagactca
      241 agcgattgtc acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca
      301 tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc
      361 tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactt cacgtaaatc
      421 cagcaaactc aaaccgctaa cagttgaaga taaagcctgt aaccatgcgc tatctaagga
      481 gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac
      541 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa
      601 tcatgaacta ggattctagt tttgcaggaa gtctaatgta atttttgcaa ttcaagacgt
      661 ttcgatgact attcaagatc tggatgaaaa attttaaaaa acgatgatat actaaacttg
      721 tcaaagttac aacaagacaa aaattaaaaa taaaaaagag tatttgtcat ggatacaaaa
      781 attatggaac aatttcatga aatggatata actatgttat ctagtattga aggaggcaag
      841 aataattggc aaactaatgt cttagaaggt ggtggtgctg cttttggtgg ctgggggcta
      901 gggacagcta tttgtgctgc gagtggtgtt ggagcaccat ttatgggagc atgtggatac
      961 ataggagcta aatttggtgt ggatctttgg gcaggagtaa caggggcaac gggtggattt
     1021 taataaaagg agacttgtat gaatacttat tgtaatataa atgaaacaat gctgagtgag
     1081 gtttatggag gtaattccgg aggagcagct gtagttgctg ctttaggttg tgcagcgggt
     1141 ggagtgaaat atgggagact tctaggacca tggggcgctg caataggagg aattggagga
     1201 gcagtggttt gtggatattt agcctatacc gctacatcat aaaaatgaaa gctaaatttt
     1261 atgaaggcta tattctttat tattctcttc gcttttcaaa cctatcttat ttatctatcc
     1321 ataagtatct c
//
LOCUS       DAVLZG010000124         1281 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLZG010000124 DAVLZG010000000
VERSION     DAVLZG010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.124"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..235
                     /locus_tag="VYO72_002039"
     CDS             <1..235
                     /locus_tag="VYO72_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708329.1"
                     /translation="DNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEF
                     IACLNSRCMPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            550..>1281
                     /locus_tag="VYO72_002040"
     CDS             550..>1281
                     /locus_tag="VYO72_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708330.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPI"
BASE COUNT          430 a          175 c          212 g          464 t
ORIGIN      
        1 cgataatgaa gcattaagag atttgtcaaa acaatattta aacaaaaata tttcggaatt
       61 acaagatggt tctttcgagg gcggtataca agatgctgtt gcctctaaac aaatagtagt
      121 tataaatgaa tttatagctt gtttaaattc cagatgcatg ccatcccaat atgatagatt
      181 tttttataaa gatagacctt atattttttc cagaaagagt cctattaagg ggtgaaaatt
      241 tgttacattt ggattaacaa gtgtcctagg gattagaaat aactctagta tagctagata
      301 tttttgagta actagaaata tcattagtct acccatatga ttgccagaaa agatggctga
      361 tgaatcttat ttatactgtt gcagtaggcg ttgtctagga taaataagct atcttgatgg
      421 gggagattgg aataatttta gtagaaacat taaaggatta tggacaagta gcgtaggatt
      481 aggtgatgca atgtgctaag ttggcttggt gttaacagta gtattattta acaatggaaa
      541 gtagactaaa tgaaaaataa gcgttatttt tttgacacaa ttttaataat tttactgctt
      601 ataagcacga tattttgtgt cagcccagta tttataaaat tggacatctt aggaactccc
      661 tctcatgcca tcttaacctt tgtattggcg ataccgttat tctatatttt gtctcaatgc
      721 ttacatactt tgctattact agtttcctca atcttttgta aattaagacc aatttatttt
      781 tattttatat ttgtgatcat tataggagct aggaaatact atcgaattct ctttcaccaa
      841 ctaatgggat ttagtccagg aatagcagtg ttttataagg agagtcaaac aactaagaat
      901 ctgtttaaat tttactactt cttgtacttt acaacactaa tttcatacta ttttttcttt
      961 acttttgtgt atgacaaacc gttgcttttg cctcttattt cattttctat tatcatagca
     1021 ttagtacaaa aactttatag aattgagaat caacaattat ttctgttaaa atcaaaggta
     1081 ctaacaatac tggaatctaa gaagaattgt gagtttaatc ttcaggatta tcatgaaatt
     1141 tggaaattgc aatcaaaatc tgagttgcca tgcgtggctt tatcttatat cagtttaatc
     1201 aagccatatc tttcagagag tgtgcgtgaa caaattgatt tattagaagt taagcgattt
     1261 aaaaaaataa ataatccaat a
//
LOCUS       DAVLZG010000125         1279 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLZG010000125 DAVLZG010000000
VERSION     DAVLZG010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.125"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            2..559
                     /locus_tag="VYO72_002041"
     CDS             2..559
                     /locus_tag="VYO72_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1708331.1"
                     /translation="MFGVGMMGLIPILFLIYPTVLAIVAGTVVMLFMAKVQKPWALFI
                     FGMISPLVMFAAGHTYIVVVLSLIVMIIAELIRKIGNYNSFKYNMLSYAIFSTWICSS
                     LMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYPHMALVALGAFLGGILGAYIGKALL
                     KKHFSNGLYCVGYFTPCLILWCYLN"
     gene            460..1017
                     /locus_tag="VYO72_002042"
     CDS             460..1017
                     /locus_tag="VYO72_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1708332.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            1005..>1279
                     /locus_tag="VYO72_002043"
     CDS             1005..>1279
                     /locus_tag="VYO72_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1708333.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKT"
BASE COUNT          427 a          172 c          248 g          432 t
ORIGIN      
        1 catgtttgga gttggtatga tgggcttgat tccaatattg ttcttaatat acccgacagt
       61 attagccata gttgcaggaa ctgttgttat gttatttatg gctaaggttc aaaagccatg
      121 ggcactattt atatttggta tgatatcacc acttgtgatg tttgcagctg gtcataccta
      181 catagttgtg gttttatcac ttatagtaat gataatagca gaattaatta gaaagattgg
      241 taattataat tcatttaaat acaatatgct ttcttatgca atcttcagca catggatatg
      301 tagctcttta atgcaaatgc ttttagcaaa agaaaaatat atggagtggt ctttgatgac
      361 gatgggaaaa gattatgttg atgtattaga aaagttaata acttatcctc acatggcttt
      421 agtagcctta ggtgctttct taggaggaat tcttggagca tatataggca aggctctatt
      481 gaaaaaacac ttttcaaatg gattatattg tgtgggatac tttactcctt gcctaatttt
      541 atggtgttat ctgaattaaa ccctatagtt aagatgtttt tgagtatacc tattgttatt
      601 agaatgttta ttttaccatt tatggcagca agctttatga taaagacctc ggatgtaggc
      661 gcaataattt catcgatgga taagcttaag atttcaaaga atgtatccat acctattgcg
      721 gttatgttta gattcttccc atcttttaag gaggagaaga aaaacatcaa aatggctatg
      781 agagtaagag ggataaattt taaaaaccca gtcaaatatc ttgaatatgt ttctgtgcca
      841 ctactcatta tatcatctaa tatatcagat gacattgcaa aagcggcaga aacaaaggca
      901 atagaaaatc caattgccaa gaccagatac attcgcgtaa agatacagct aattgatttt
      961 gtttatgttt tagcggttgc tggacttatt gtgggaggat taatatggtt gaaataaaaa
     1021 atttaagtct tgattatggt gaagagcata tattagatga tatatcacta tccatagccg
     1081 agggagagtg cgtgctattt acaggaaaaa gtggaaatgg taagtcatct ttaataaatt
     1141 caatcaatgg actagctgta aggtatgaca acgcaaagac aaagggcgaa ataattattg
     1201 atggtaagaa tataaaaaat ttggaacttt atcaaatctc aatgcttgtt tcaactgttt
     1261 ttcaaaatcc taagacata
//
LOCUS       DAVLZG010000126         1202 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLZG010000126 DAVLZG010000000
VERSION     DAVLZG010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.126"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..676
                     /locus_tag="VYO72_002044"
     CDS             <1..676
                     /locus_tag="VYO72_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708334.1"
                     /translation="GKSTLIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQ
                     SPIIPESITVADLVSRGRFPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSG
                     GQRQRVWIALALAQDTSILLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDI
                     NLTARYADYLFAIKEGKLVAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIG
                     KHHVNS"
BASE COUNT          492 a          191 c          189 g          330 t
ORIGIN      
        1 tgggaaatca acactcatta aaaccttgtc tcgacttata aagccattag agggagaagt
       61 attgcttgat aataaatcaa ttaattctta taaagaaaaa gatttagcaa aacacatagc
      121 tatattacct caatctccaa taatccctga atcaataaca gtagctgatc ttgtaagccg
      181 tggtcgtttc ccctacagaa agccttttaa gagtcttgga aaagatgacc ttgaaataat
      241 aaacagatca atggttaagg ccaatgttga agatctagca aataacctag ttgaagaact
      301 ttctgggggt caaaggcaaa gagtatggat agctctagcc ctagcccaag atacaagtat
      361 cctactttta gatgagccaa ctacttactt ggatatctca tatcaaatag aactattaga
      421 cctcttgact gatctaaacc aaaaatataa gacaaccatt tgcatgattt tgcacgatat
      481 aaatctaaca gcaagatacg ctgattacct atttgcaatt aaagaaggta aacttgttgc
      541 agagggaaag cctgaagata tactaaatga taaactagtt aaagatatct ttaatcttga
      601 agcaaaaatt atacgtgacc ctatttccaa ttcgcctcta atgattccta ttggcaagca
      661 ccatgttaac tcttaataat tgaatattgg aattcattta aaagtcgcaa attttgaact
      721 gaccctcaaa agttaggcca aaaaactaac taaaggaggt cagtttttta atggcaaata
      781 cagcacagaa tttaagataa aattagtaaa agaatatcat gaatgaaaaa taggatatag
      841 agaataacag caatattaaa aagatcagga ctgataataa acaaaaagaa agtacaacga
      901 ctagttcaaa agctaaaact tcaagtaaaa agttattcaa gaaaatctag aaaatactca
      961 tcctacaaag gacaggtagg aaaaatatca gacaacaaaa taaaaagaaa tatttattac
     1021 cgaaaaaaag gggaaatcga gttaagtacc aacaggctca tctattccaa aaagatattt
     1081 actcgatgga aaaactccta gaattagtgc tacaaatatt gacaatggta tcttaggtta
     1141 ctacgaagat atagatgata aaaattatag agtctttgaa aattttatat ctgtttcatt
     1201 tt
//
LOCUS       DAVLZG010000127         1053 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLZG010000127 DAVLZG010000000
VERSION     DAVLZG010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.127"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            8..>1053
                     /locus_tag="VYO72_002045"
     CDS             8..>1053
                     /locus_tag="VYO72_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1708335.1"
                     /translation="MENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILC
                     IAASYIAGTKIIVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVD
                     RVFLIDKGKLKKTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSY
                     KFTDDECLSLKDISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSK
                     KERLKNSSLVMQDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMS
                     LSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSH
                     DIEFLNEVADEIFE"
BASE COUNT          412 a          114 c          200 g          327 t
ORIGIN      
        1 attttatttg gaaaatatcg gtcttgcaag agaagagatg gacaggcgtt tgaaggatat
       61 gcttgagata ttcccgataa aaaatctttt aaacagaaat atatttaatc tatccggcgg
      121 tgaaaaacaa attctttgca ttgcagcttc ttatatagca ggtacaaaga ttatagttat
      181 ggatgagcct tcatcgaatt tagatattaa aagcataagt gttttggcaa agatgctaaa
      241 gatattaaaa gagaaaggca taagcataat tgttgcagag catagaattt attatttgat
      301 ggacatagtt gaccgtgtat ttttaataga taaaggaaag cttaaaaaaa cttatactag
      361 aagtgaattt ttaaagctag ataaaaatga attaaatgct ttaagtttaa gagataaaga
      421 attaagtaaa ttaaaagttc cttatttaaa agaaggtgga gagtatcaga taaaaaatct
      481 tagctacaaa tttactgatg atgagtgttt aagcttaaaa gatatttcgt tcaagcttgg
      541 gaaaatttat ggcataatag gatccaacgg acgaggaaaa tcaacgcttt taagatgttt
      601 aataggtctt gagaaaaaat caaaagaaga aatttatttt aagggagaga agctatctaa
      661 aaaagaaaga ctcaaaaact cttcacttgt tatgcaagat gtaaatcatc aattattcac
      721 agatgaagta ttcaacgagc ttagattagg agtaaagaat tttgatgaag aaaaggcgaa
      781 aatcatctta aaagatttag gcctggacga atttattgaa aggcatccga tgagtttatc
      841 aggagggcaa aagcaaaggc ttgcaatagc atctgttatg tgcaagaatt ctccatttgt
      901 cttttttgac gaaccttcaa gtggtatgga ttattccaat atgataaaaa tatctgaact
      961 gattaataag tataaaacca tggataaaat aatttttatt gtttcccatg atatagaatt
     1021 tttaaatgaa gtggcagatg aaatttttga att
//
LOCUS       DAVLZG010000128         1053 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLZG010000128 DAVLZG010000000
VERSION     DAVLZG010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.128"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..559
                     /locus_tag="VYO72_002046"
     CDS             <1..559
                     /locus_tag="VYO72_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1708336.1"
                     /translation="NKDETTSYPIYEIPKAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(507..1049)
                     /locus_tag="VYO72_002047"
     CDS             complement(507..1049)
                     /locus_tag="VYO72_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1708337.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINKGVRIIRGGNIKPLEF
                     SLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIFQ
                     LTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFEE
                     QELITQKVEKLFEKVNQLWK"
BASE COUNT          379 a          168 c          154 g          352 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccaaaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cctgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat ttccaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgcttagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtgtc aatgtagtaa
      901 tcattatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattaa tgcttaaatc gcccttcttg taagaaagac ctgtatttat tgaaaaaata
     1021 tcttttattt ttataacaac ccaattcata ggt
//
LOCUS       DAVLZG010000129          922 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLZG010000129 DAVLZG010000000
VERSION     DAVLZG010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.129"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            143..922
                     /locus_tag="VYO72_002048"
                     /pseudo
     CDS             143..922
                     /locus_tag="VYO72_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT          321 a          159 c          190 g          252 t
ORIGIN      
        1 tagaggccta tttaccgtgg actaaagttg tacaagaaaa gtgcaaataa gaaatctcca
       61 gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatagact tcctgcgaaa
      121 caaaatatgg tataatagtt ctatgaatta tgaagcaagt aaacaactaa ccgatgcacg
      181 atttaagcgt cttgttggtg ttcaacgcac gacttttgaa gagatgttag ctgtattaaa
      241 aacagcttat caacttaaac acgcaaaagg tgggcgaaaa cctaaattaa gcctagaaga
      301 ccttcttatg gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc
      361 tgatcttggt attcacgaaa gcaacttaat ccgtcggagc caatgggttg aagtaactct
      421 tgttcaaagg tggtgttgcg atttcaagaa ctcctctcag ttctgaggac acggtaatga
      481 ttgatgcgac ggaagtaaaa atcaatcgac ctaaaaaaag aattagcgaa ttattctggt
      541 aaaaagaaat ttcacgctat gaagactcaa gcgattgtca caagtcaagg gagaattatt
      601 tctttggata tcgctgtgaa ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga
      661 aatatcggac aagctggtaa aatcttggct gacagtgatt atcaagggct catgaagata
      721 tatcctcaag cacaaattcc acgtaaatcc agcaaactta agccgctaat agctgaagat
      781 aaagcctata actatgcgct atctaaggat agaagcaagg ttgagaacat ctttgccaaa
      841 gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg ctttggatta
      901 cgaatgaatt tgagtgctgg ta
//
LOCUS       DAVLZG010000130          910 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLZG010000130 DAVLZG010000000
VERSION     DAVLZG010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.130"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            1..823
                     /locus_tag="VYO72_002049"
                     /pseudo
     CDS             1..823
                     /locus_tag="VYO72_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            816..>910
                     /locus_tag="VYO72_002050"
     CDS             816..>910
                     /locus_tag="VYO72_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1708338.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCL"
BASE COUNT          334 a           79 c          193 g          304 t
ORIGIN      
        1 attttttata tatgttaaaa aaacttgaca agaatggatt tggaaaggtt aagacagtga
       61 taacatgcca tggatgggtt gaatataact taaaaaagaa attcttgact tattttgatt
      121 tttggacata ttctatggga gatgctttta tttgtgtatc tgaaactatg aaaaaaagat
      181 tggagagtat aataaaaaaa taagaagata gttgcaataa ataacggaat taatgtatca
      241 aatagcgatt tagatgtagt aggtgttcaa gactttaaaa aagaattttg tattccaaat
      301 aacaaaaaaa tcatttgtta tgttggaagg ttggatccag aaaaaaggcc ggatagattc
      361 cttgaatttg cagaaaaatt atttttagtc agagaagatg tgatttttat tatggctgga
      421 aatggtagta tgtgggctgc tttgaaagaa aaaatttgcc atttgaaatg tagagataat
      481 ttcaggttac ttggtgaaat ctatccagct actatagttt accaaatatc ggatttattg
      541 tatattcctt ctgatacaga aggaatacct atgtgtgttt tagagtcaat gtcacaagga
      601 actccggttt tagctagtaa tgttggcggg ttaagtgaaa ttattgaaca tagggttgat
      661 ggatttttat ttgagaagga agatgttgag ggagtgtgtg cttgtgctaa ttttttactc
      721 aatgattctg agtatttgaa atatataggt gagaatagta aatcaaaaat aagaaaacat
      781 gagagtatat gatgaattat tagagaagag tagtcatgga taggaatata gatcaagaat
      841 tagtaagtat tataatacca acacataata ggtatgaatc tctgattaga gctgtgaaaa
      901 gttgtttaca
//
LOCUS       DAVLZG010000131          729 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLZG010000131 DAVLZG010000000
VERSION     DAVLZG010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.131"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(323..622)
                     /locus_tag="VYO72_002051"
                     /pseudo
     CDS             complement(323..622)
                     /locus_tag="VYO72_002051"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          223 a          126 c          130 g          250 t
ORIGIN      
        1 ggggtgcata attggggttt atataattta tttcatattt tgtaaggtca gtgtgaaaat
       61 atttaaatag acttcctgta aaaactggat ttaacgccct ccatttgtca aattaagcta
      121 gacagtctta ccaactcaga aaatacctga tgaggtattt ggtatccaaa ggatttaggt
      181 gggatgtgat ttcttgaggc tgggaaaaag tctttaaaat taaaaaatgt ataatatcag
      241 gtgttggaaa aactttgata ctatgcgttt tattgtggga atatttattt cattttctcc
      301 tgaaattgag tttttaccca gcctaaaatt cttgactgac ttcgttgaaa tctgtctgct
      361 ttggcaagtc atgacacctt aaaagtctat ttgaatgttc gttgagacac cgctgtcttg
      421 gacatcctag attcgcaaaa aagctctcac tatcgtgatg attggaaata tctttccatt
      481 ttgaaaactc ttttccacag tcaaacgtaa tagatttaaa gaggttcact agaaattgtg
      541 ccagccaccc ttggatggat tctgccatat cctttgcctt acgactcttg gtcttcaaac
      601 tgacaatcaa ttgactatac ctgttcgctc acaaatagga gagaactttt tacgaaaatc
      661 taatgaatat gccacaagaa cattataccg caacgtgtac tatttttggt tcattttact
      721 atagaaact
//
LOCUS       DAVLZG010000132          546 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLZG010000132 DAVLZG010000000
VERSION     DAVLZG010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.132"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..>546
                     /locus_tag="VYO72_002052"
     CDS             <1..>546
                     /locus_tag="VYO72_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1708339.1"
                     /translation="RNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISF
                     LDDDDEYMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQ
                     MVHNIAGTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYA
                     HSKENGITGVTQKTINADEEY"
BASE COUNT          207 a           61 c          107 g          171 t
ORIGIN      
        1 aagaaataaa attatccatc aatttggcta taccaatcat agaattaagt taattttaag
       61 taatgaagat ttaggtgcaa ctaatgccag aaacataggt atcaaaaatt ctagaggtaa
      121 gtatatatca tttttagacg atgatgatga atatatgcca gatcgaattt taaagttgat
      181 ggcttgtttt aaaaagagta gaatgaagaa tttagcttta gtttatagtt atggaataat
      241 aatttatcca aatggtacac gagaagagga gaagaccgat tttgttggaa atcccttgtt
      301 tgttcaaatg gttcacaata tagcaggtac gtcattttgg ttgtgtaaaa aagaggtgct
      361 agaattaatt aatggttttg agaaaataga ttcacatcag gacggtgttg ttttattaaa
      421 actacttgct caaggatacc aaattgatat agtgcgagaa ttcttggtga attactacgc
      481 tcacagtaaa gaaaacggta tcactggagt gacacaaaaa acaattaatg cagatgaaga
      541 atatta
//
LOCUS       DAVLZG010000133          521 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLZG010000133 DAVLZG010000000
VERSION     DAVLZG010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.133"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..429
                     /locus_tag="VYO72_002053"
     CDS             <1..429
                     /locus_tag="VYO72_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1708340.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDETEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT          198 a           85 c          110 g          128 t
ORIGIN      
        1 gaccatgttc gtaaaaataa ggcagaccaa gacagtaaac ctgatgaaga taagggacat
       61 gatgaagtaa gtgagccaac tcaccctgaa tctgatgaaa aagagaatca cgctggttta
      121 aatccttcag cagataatct ttataaacca agcactgata cggaagagac agaggaagaa
      181 gctgaagata ctacagatga gactgaaatt cctcaagtag agcattctgt gattaacgct
      241 aagatagcag aggcggaggc cttgctagaa aaagtaacag attctagtat tagacaaaat
      301 gctatggaga cattgactgg tctaaaaagt agtcttcttc tcggaacgaa agataataac
      361 actatttcag cagaagtaga tagtctcttg gctttgttaa aaaaaagtca accggctccg
      421 atacagtagt aaaatgaatg gagcatattt tatggagaag taacctttcg tgttacttct
      481 cttttttaga aaaacgtaac agaaacttga caaaagtaat t
//
LOCUS       DAVLZG010000134          499 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLZG010000134 DAVLZG010000000
VERSION     DAVLZG010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.134"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..>499
                     /locus_tag="VYO72_002054"
     CDS             <1..>499
                     /locus_tag="VYO72_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1708341.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMP
                     YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPN
                     ERPHS"
BASE COUNT          161 a          104 c          113 g          121 t
ORIGIN      
        1 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
       61 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      121 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      181 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      241 caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg ccacttgatc
      301 gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta atcatacctc
      361 attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt tatgaggcac
      421 ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc gaacatccaa
      481 acgaacgtcc gcattcaga
//
LOCUS       DAVLZG010000135          498 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLZG010000135 DAVLZG010000000
VERSION     DAVLZG010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.135"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..>498)
                     /locus_tag="VYO72_002055"
     CDS             complement(<1..>498)
                     /locus_tag="VYO72_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1708342.1"
                     /translation="ILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQLASQPTLS
                     RFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHY
                     RAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFAT
                     PKLYD"
BASE COUNT          160 a           96 c          115 g          127 t
ORIGIN      
        1 aatcgtataa ttttggggtc gcaaagccac tatccattcg aaagagaagt tgattaaacc
       61 gttctaaaac aggtgtgata aagctgtctg cctcttcaga acaataacga ttaccaggac
      121 gaagctgggc attgaaacaa taacctgtct tcccctcgaa agcataaaga ggatgatagc
      181 catgagcacg atagtgggcg ttataagcaa caccttcttg cttgccataa gttgtgaaat
      241 gggtagaatc gatatctaca atgagttggt ttagctggtg aaactgtaaa aagaattcga
      301 ccaattcaag gttgaggcat cgcaaactat ggactgtttc ctcgtcagtt ctggaaagaa
      361 aacgggataa ggttggctgt gaagcaagct gccctccttc caacaatttt ggaaagtagg
      421 catcagctga caattcttta caagcatagt ccgttccata gcctgttaac agttgaaaga
      481 ggaactggac aaggatat
//
LOCUS       DAVLZG010000136          498 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLZG010000136 DAVLZG010000000
VERSION     DAVLZG010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.136"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(11..>498)
                     /locus_tag="VYO72_002056"
     CDS             complement(11..>498)
                     /locus_tag="VYO72_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV1708343.1"
                     /translation="NLGGGFMKLFMENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSA
                     ITSFSAYMITSPVNVSEVNEQQVITLDTSIYTNTLWFVPHIITTLNSSSKERYSTILY
                     GNTCYEHDKYKMKVSLPRLTQNSSIVFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLT
                     Y"
BASE COUNT          169 a           87 c           67 g          175 t
ORIGIN      
        1 ttaactttat ctaatatgtc aagttttttg tccacaaata tacctcccgc ataaaatcat
       61 tacgatgtaa atttgaatga ttgcttttta tataagctcc tacaggaaaa aacactatac
      121 tgctattttg agttaacctt ggaagcgaaa ctttcatttt atacttgtca tgttcataac
      181 aggtattacc atagagaata gtactataac gctctttact acttgaattt aacgttgtaa
      241 taatatgcgg aacaaaccat aatgtattgg tgtatattga tgtgtctaac gtgataacct
      301 gctgctcatt cacctcacta acattaactg ggctagtaat catataggca gaaaatgaag
      361 taattgcact acctggttct attattgtag tcacagtact atcaatatcg tactttttat
      421 agatttccat aagtgataga aaaaattctt tcaaacgatt ttccataaat aatttcataa
      481 aaccgcctcc aagattta
//
LOCUS       DAVLZG010000137          459 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLZG010000137 DAVLZG010000000
VERSION     DAVLZG010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.137"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            8..226
                     /locus_tag="VYO72_002057"
     CDS             8..226
                     /locus_tag="VYO72_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1708344.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          193 a           53 c           88 g          125 t
ORIGIN      
        1 ggatattatg gcacttaact ataaaccatt atggatacag ttagcaaaaa aaggactaaa
       61 gaaaacagat gtaatagcta tggcaggact tacaacaaat gttatggcac aaatgggaaa
      121 ggataaacca attacattta agaatttaga aagaatatgt aaggctttat cttgcactcc
      181 taatgatatt attagttttg aagataattt tagtgacgag gaatagaaaa tgactttaag
      241 gacagaagat caagttaggg attatgcaag agaagtatag gctttaatga agttgaagaa
      301 aacatcaatc aaggtactgg tcaaataact acttttaatc aattaggctt caagggatat
      361 tcagataagc cagatggttg gtatttacct aaaaatatga atgatgtagc aataatcctt
      421 gaaacaaaat cagaagaaag agatattagc aaacaaatt
//
LOCUS       DAVLZG010000138          426 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLZG010000138 DAVLZG010000000
VERSION     DAVLZG010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.138"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            <1..>426
                     /locus_tag="VYO72_002058"
     CDS             <1..>426
                     /locus_tag="VYO72_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1708345.1"
                     /translation="LLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCPECGSQMKKY
                     DFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIA
                     QKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLP"
BASE COUNT          144 a          101 c           61 g          120 t
ORIGIN      
        1 ttactagaca ttaaagaccc taatatccag attttagaca tcatcaataa agatacacac
       61 aaggaaatca tcgccaaact ggactacgac gccccatctt gccctgagtg cggaagtcaa
      121 atgaagaaat atgactttca aaaaccttct aaaattcctt atcttgaaac aactggtatg
      181 ccttctagaa ttctccttag aaaacgccgt ttcaagtgct atcactgttc aaaaatgatg
      241 gttgctgaga ctcccctggt aaagaaaaat caccaaatcc ctcgtatcat caaccaaaaa
      301 attgctcaaa agttaattga aaaaatttct atgactgata ttgcccatca gctggccatt
      361 tcaacttcaa ctgtcattcg caagctcaat gactttcact ttgagcatga tttttctcgg
      421 cttcca
//
LOCUS       DAVLZG010000139          420 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLZG010000139 DAVLZG010000000
VERSION     DAVLZG010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.139"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            complement(<1..286)
                     /locus_tag="VYO72_002059"
     CDS             complement(<1..286)
                     /locus_tag="VYO72_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1708346.1"
                     /translation="MAVIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLYAISVS
                     IIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYL"
BASE COUNT          175 a           66 c           66 g          113 t
ORIGIN      
        1 ataaatagaa aatgtaagat aatagaaaat aaaacaggac taacaaaatt gtattgacta
       61 caatagctac tataaaatct aatcctaaat cacctggaat acccaattta cttactatga
      121 ctagtaacac aatgccattc aaagcataaa taatggaaac tgagatggca tatagaaaat
      181 tagacaagag gtaaatcatc cgatttttct gttgattata aaataaactg atcgtattgt
      241 gggaaaaatc cctgctaata attcggttag catgtataac agccattaac ataccgagca
      301 tagcataaaa gtttgaaata tgcttaatac caagcgatgt cccttgagtc tttagaataa
      361 agaatgtaag caatatcggc ggtataaacg agataatcaa accgagatat attacgcctg
//
LOCUS       DAVLZG010000140          398 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00020589
            SAMN33607282-rid17938873.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLZG010000140 DAVLZG010000000
VERSION     DAVLZG010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607282
            Sequence Read Archive: SRR23725493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721370.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721370.1
            Genome Coverage       :: 111x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:20:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,061
            CDSs (total)                      :: 2,015
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 61 of 124
            Pseudo Genes (internal stop)      :: 38 of 124
            Pseudo Genes (multiple problems)  :: 26 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607282-rid17938873.denovo.140"
                     /strain="AUSMDU00020589"
                     /serotype="22F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST433"
     gene            23..172
                     /gene="blpO"
                     /locus_tag="VYO72_002060"
     CDS             23..172
                     /gene="blpO"
                     /locus_tag="VYO72_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1708347.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            276..395
                     /locus_tag="VYO72_002061"
     CDS             276..395
                     /locus_tag="VYO72_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1708348.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
BASE COUNT          122 a           43 c          103 g          130 t
ORIGIN      
        1 taactgaaaa gtgatatact atatggatac aaaaatgatg tcacaatttg cagttatgga
       61 taatgaaatg cttgcttgcg ttgaaggtgg agatattgat tggggaagaa aaattagttg
      121 tgcagcaggg gttgcatatg gcgcaattga tgggtgtgca acaacggttt gacatttcta
      181 ttgggaccat ttgctatagg aataggtgta actggtgctg cgggaggagc tatacttgga
      241 ggtgtggcct atgcagcgac atgttggtgg taattatgga ttttaaaagt tttattattg
      301 gtttagtagt tggtatattt ggtccttata tggatgactt aattagaaaa atattttcaa
      361 aatcttccaa aaaggatacg gatagtactc tctaaaaa
//
